C. Jiménez-Pérez, S. Alatorre-Santamaría, S. Tello-Solís, L. Gómez‐Ruiz, G. Rodríguez-Serrano, M. García‐Garibay, A. Cruz-Guerrero
Due to the carcinogenic character of aflatoxins when present in foods, these compounds are considered a risk to human health. This systematic review aimed at compiling the available research data on detection and quantification of aflatoxin M1 (AFM1) in milk and common types of cheese produced in Mexico in the past two decades. A limited number of studies were found that matched the purpose of our review. Only ten research works focused on the evaluation of AFM1 content in milk while three studies analysed the occurrence of this mycotoxin in oaxaca and panela cheeses. HPLC-FD and ELISA were the methods of choice utilised to detect AFM1. Concentrations higher than 0.5 μg AFM1/kg, a maximum limit set in current food regulation in Mexico, were found in major dairy brands consumed in Mexico. Analysis of raw milk produced during the rainy season in the states of Jalisco (2007) and Chiapas (2013) showed mycotoxin levels within the regulation limits while milk samples obtained during the dry season in the Mexico City and the State of Mexico (2008) exceeded that threshold. For cheeses, 33% of the artisanal produced oaxaca type samples from Veracruz (2016) and 55% of those acquired in Mexico City (2019) were found above the limit set for milk. In contrast, the panela cheese samples obtained in Baja California and Guanajuato (2009) complied with the AFM1 regulation. Additionally, the presence of AFB1 and its hydroxylated metabolites other than AFM1 were determined in the major milk brands at concentrations that could be of high risk for human health. Similar results were reported for both artisan and industrially produced oaxaca cheese. Finally, mycotoxins enter human food chain through animals fed with contaminated fodder. Our systematic review demonstrated the urgent need to amend the existing food regulation in Mexico to include mycotoxins as potent contaminants in cheese.
{"title":"Analysis of aflatoxin M1 contamination in milk and cheese produced in Mexico: a review","authors":"C. Jiménez-Pérez, S. Alatorre-Santamaría, S. Tello-Solís, L. Gómez‐Ruiz, G. Rodríguez-Serrano, M. García‐Garibay, A. Cruz-Guerrero","doi":"10.3920/wmj2020.2668","DOIUrl":"https://doi.org/10.3920/wmj2020.2668","url":null,"abstract":"Due to the carcinogenic character of aflatoxins when present in foods, these compounds are considered a risk to human health. This systematic review aimed at compiling the available research data on detection and quantification of aflatoxin M1 (AFM1) in milk and common types of cheese produced in Mexico in the past two decades. A limited number of studies were found that matched the purpose of our review. Only ten research works focused on the evaluation of AFM1 content in milk while three studies analysed the occurrence of this mycotoxin in oaxaca and panela cheeses. HPLC-FD and ELISA were the methods of choice utilised to detect AFM1. Concentrations higher than 0.5 μg AFM1/kg, a maximum limit set in current food regulation in Mexico, were found in major dairy brands consumed in Mexico. Analysis of raw milk produced during the rainy season in the states of Jalisco (2007) and Chiapas (2013) showed mycotoxin levels within the regulation limits while milk samples obtained during the dry season in the Mexico City and the State of Mexico (2008) exceeded that threshold. For cheeses, 33% of the artisanal produced oaxaca type samples from Veracruz (2016) and 55% of those acquired in Mexico City (2019) were found above the limit set for milk. In contrast, the panela cheese samples obtained in Baja California and Guanajuato (2009) complied with the AFM1 regulation. Additionally, the presence of AFB1 and its hydroxylated metabolites other than AFM1 were determined in the major milk brands at concentrations that could be of high risk for human health. Similar results were reported for both artisan and industrially produced oaxaca cheese. Finally, mycotoxins enter human food chain through animals fed with contaminated fodder. Our systematic review demonstrated the urgent need to amend the existing food regulation in Mexico to include mycotoxins as potent contaminants in cheese.","PeriodicalId":23844,"journal":{"name":"World Mycotoxin Journal","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41730241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Higashioka, A. Kluczkovski, E. S. Lima, A. Lucas
The present study was a pilot study that aimed to evaluate the occurrence of aflatoxins (AF) in the human diets and its presence in human urine as a metabolite (aflatoxin M1; AFM1). Volunteers from...
{"title":"Biomonitoring aflatoxin B1 exposure of residents from the Amazon region: a pilot study","authors":"K. Higashioka, A. Kluczkovski, E. S. Lima, A. Lucas","doi":"10.3920/WMJ2020.2627","DOIUrl":"https://doi.org/10.3920/WMJ2020.2627","url":null,"abstract":"The present study was a pilot study that aimed to evaluate the occurrence of aflatoxins (AF) in the human diets and its presence in human urine as a metabolite (aflatoxin M1; AFM1). Volunteers from...","PeriodicalId":23844,"journal":{"name":"World Mycotoxin Journal","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46272101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Verheecke-vaessen, A. Lopez-Pietro, E. García-Cela, Á. Medina, N. Magan
The objective of this study was to evaluate the potential intra-species variability of 3 Fusarium langsethiae strains in response to extreme climate change (CC) conditions on an oat-based matrix. The impact of elevated temperature (25 vs 30-34 °C) coupled with increasing drought stress (0.98 vs 0.95 aw) and elevated CO2 (400 vs 1000 ppm) were examined on lag phases prior to growth, growth rate, and production of the mycotoxins T-2 and HT-2 and their ratio. In comparison to the control conditions (25 °C; 0.98; 400 ppm), exposure to increased temperature (30-34 °C), showed similar reductions in the lag phase and fungal growth rates of all 3 strains. However, with elevated CO2 a reduction in both lag phases prior to growth and growth rate occurred regardless of the aw examined. For T-2 and HT-2 mycotoxin production, T-2 showed the most intra-species variability in response to the interacting abiotic stress factors, with the 3 strains having different environmental conditions for triggering increases in T-2 production: Strain 1 produced higher T-2 toxin at 25 °C, while Strain 2 and the type strain (Fl201059) produced most at 0.98 aw/30 °C. Only Strain 2 showed a reduction in toxin production when exposed to elevated CO2. HT-2 production was higher at 25 °C for the type strain and higher at 30-34 °C for the other two strains, regardless of the aw or CO2 level examined. The HT-2/T-2 ratio showed no significant differences due to the imposed interacting CC abiotic conditions.
{"title":"Intra-species variability in Fusarium langsethiae strains in growth and T-2/HT-2 mycotoxin production in response to climate change abiotic factors","authors":"C. Verheecke-vaessen, A. Lopez-Pietro, E. García-Cela, Á. Medina, N. Magan","doi":"10.3920/wmj2020.2584","DOIUrl":"https://doi.org/10.3920/wmj2020.2584","url":null,"abstract":"The objective of this study was to evaluate the potential intra-species variability of 3 Fusarium langsethiae strains in response to extreme climate change (CC) conditions on an oat-based matrix. The impact of elevated temperature (25 vs 30-34 °C) coupled with increasing drought stress (0.98 vs 0.95 aw) and elevated CO2 (400 vs 1000 ppm) were examined on lag phases prior to growth, growth rate, and production of the mycotoxins T-2 and HT-2 and their ratio. In comparison to the control conditions (25 °C; 0.98; 400 ppm), exposure to increased temperature (30-34 °C), showed similar reductions in the lag phase and fungal growth rates of all 3 strains. However, with elevated CO2 a reduction in both lag phases prior to growth and growth rate occurred regardless of the aw examined. For T-2 and HT-2 mycotoxin production, T-2 showed the most intra-species variability in response to the interacting abiotic stress factors, with the 3 strains having different environmental conditions for triggering increases in T-2 production: Strain 1 produced higher T-2 toxin at 25 °C, while Strain 2 and the type strain (Fl201059) produced most at 0.98 aw/30 °C. Only Strain 2 showed a reduction in toxin production when exposed to elevated CO2. HT-2 production was higher at 25 °C for the type strain and higher at 30-34 °C for the other two strains, regardless of the aw or CO2 level examined. The HT-2/T-2 ratio showed no significant differences due to the imposed interacting CC abiotic conditions.","PeriodicalId":23844,"journal":{"name":"World Mycotoxin Journal","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44555745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
X. Li, H. Li, Wen Zhang, Qi Zhang, Z. Guo, S. Song, G. Zhao
The certified reference materials (CRMs) are necessary for accurate quantification and insurance of comparability and traceability of results. Patulin is a typical mycotoxin in a variety of food commodities. Here, patulin CRM GBW(E)100673 was characterised and its purity was assessed by two independent orthogonal approaches including mass balance (MB) and quantitative nuclear magnetic resonance spectroscopy (qNMR) methods. From MB equation, the calculated purity was 996.9 mg/g with subtraction of water, volatile solvent, inorganic and structurally related impurities. In the other qNMR method, the calculated purity was 996.7 mg/g. This CRM was homogeneous and stable for at least 9 months under -20 °C in dark. Finally, a purity of 997 mg/g with an expanded uncertainty of 3 mg/g (k=2) was finally assigned to patulin CRM in this study. High-purity patulin CRM was fully characterised and assessed for the first time. The new CRM can be applicable to routine monitoring and risk assessment for assurance of accuracy results in food safety.
{"title":"Development of patulin certified reference material using mass balance and quantitative NMR","authors":"X. Li, H. Li, Wen Zhang, Qi Zhang, Z. Guo, S. Song, G. Zhao","doi":"10.3920/wmj2021.2691","DOIUrl":"https://doi.org/10.3920/wmj2021.2691","url":null,"abstract":"The certified reference materials (CRMs) are necessary for accurate quantification and insurance of comparability and traceability of results. Patulin is a typical mycotoxin in a variety of food commodities. Here, patulin CRM GBW(E)100673 was characterised and its purity was assessed by two independent orthogonal approaches including mass balance (MB) and quantitative nuclear magnetic resonance spectroscopy (qNMR) methods. From MB equation, the calculated purity was 996.9 mg/g with subtraction of water, volatile solvent, inorganic and structurally related impurities. In the other qNMR method, the calculated purity was 996.7 mg/g. This CRM was homogeneous and stable for at least 9 months under -20 °C in dark. Finally, a purity of 997 mg/g with an expanded uncertainty of 3 mg/g (k=2) was finally assigned to patulin CRM in this study. High-purity patulin CRM was fully characterised and assessed for the first time. The new CRM can be applicable to routine monitoring and risk assessment for assurance of accuracy results in food safety.","PeriodicalId":23844,"journal":{"name":"World Mycotoxin Journal","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46213380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Pustjens, J. Castenmiller, J. D. Biesebeek, T. C. Rijk, Ruud C. J. Dam, P. Boon
In 2017, a Total Diet Study was conducted in the Netherlands in which mycotoxins were analysed in foods and beverages consumed by 1- and 2-year-old children. These mycotoxins were aflatoxins, Alternaria toxins, citrinin, ergot alkaloids, fumonisins, ochratoxin A, patulin, sterigmatocystin, trichothecenes, and zearalenone. Long-term exposure was calculated by combining concentrations in foods and beverages with consumed amounts of these products. Analysed foods and beverages with a concentration below the detection limit that could contain the mycotoxin, were assigned a concentration equal to half this limit value. To assess if the exposure could result in a possible health risk, the high long-term exposure (95th percentile) was compared with a health-based guidance value (HBGV) or a margin of exposure (MOE) was calculated. Exposure to aflatoxins, Alternaria toxins, ochratoxin A and T-2/HT-2 sum may pose a health concern. Foods that contributed most to the exposure of these mycotoxins were bread, biscuits, breakfast cereals, chocolates, dried fruit, follow-on formula and fruit juices.
{"title":"Dietary exposure to mycotoxins of 1- and 2-year-old children from a Dutch Total Diet Study","authors":"A. Pustjens, J. Castenmiller, J. D. Biesebeek, T. C. Rijk, Ruud C. J. Dam, P. Boon","doi":"10.3920/wmj2020.2676","DOIUrl":"https://doi.org/10.3920/wmj2020.2676","url":null,"abstract":"In 2017, a Total Diet Study was conducted in the Netherlands in which mycotoxins were analysed in foods and beverages consumed by 1- and 2-year-old children. These mycotoxins were aflatoxins, Alternaria toxins, citrinin, ergot alkaloids, fumonisins, ochratoxin A, patulin, sterigmatocystin, trichothecenes, and zearalenone. Long-term exposure was calculated by combining concentrations in foods and beverages with consumed amounts of these products. Analysed foods and beverages with a concentration below the detection limit that could contain the mycotoxin, were assigned a concentration equal to half this limit value. To assess if the exposure could result in a possible health risk, the high long-term exposure (95th percentile) was compared with a health-based guidance value (HBGV) or a margin of exposure (MOE) was calculated. Exposure to aflatoxins, Alternaria toxins, ochratoxin A and T-2/HT-2 sum may pose a health concern. Foods that contributed most to the exposure of these mycotoxins were bread, biscuits, breakfast cereals, chocolates, dried fruit, follow-on formula and fruit juices.","PeriodicalId":23844,"journal":{"name":"World Mycotoxin Journal","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45154099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. León-Martínez, C. M. López-Mendoza, Y. Terán-Figueroa, R. Flores-Ramírez, F. Díaz-Barriga, L. E. Alcántara-Quintana
Cervical cancer (CC) is one of the most serious threats to the lives of women; co-factors in addition to oncogenic human papillomavirus (HPV) infection may be important in causing CC. Women in Mexi...
{"title":"Detection of aflatoxin B1 adducts in Mexican women with cervical lesions","authors":"L. León-Martínez, C. M. López-Mendoza, Y. Terán-Figueroa, R. Flores-Ramírez, F. Díaz-Barriga, L. E. Alcántara-Quintana","doi":"10.3920/WMJ2020.2602","DOIUrl":"https://doi.org/10.3920/WMJ2020.2602","url":null,"abstract":"Cervical cancer (CC) is one of the most serious threats to the lives of women; co-factors in addition to oncogenic human papillomavirus (HPV) infection may be important in causing CC. Women in Mexi...","PeriodicalId":23844,"journal":{"name":"World Mycotoxin Journal","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46212481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandra Debevere, K. Demeyere, N. Reisinger, J. Faas, G. Haesaert, V. Fievez, S. Croubels, E. Meyer
In a temperate climate, the mycotoxins deoxynivalenol (DON), nivalenol (NIV), enniatin B (ENN B), mycophenolic acid (MPA), roquefortine C (ROC) and zearalenone (ZEN) are often found in maize silage. Although rumen microbiota are able to degrade some mycotoxins (e.g. DON), others are known to stay mainly intact (e.g. ROC). In addition, mycotoxin degradation can be hampered by a low ruminal pH or decrease in rumen microbial activity. Hence, these mycotoxins can reach the small intestine and exert a cytotoxic effect on intestinal epithelial cells. In this study, a real-time kinetic analysis of the cytotoxicity of these six mycotoxins and some of their metabolites (α- and β-zearalenol, α- and β-ZOL) was performed in a calf small intestinal epithelial cell line (CIEB). Confluency as well as the cell death parameters apoptosis and necrosis were determined to evaluate the mycotoxin-induced cytotoxicity. A combination of Annexin-V green and Cytotox red staining was used to determine early and late apoptosis as well as necrosis. Six different concentrations were tested ranging from 0.78 to 12.5 μM. Compared to cells not exposed to mycotoxins, DON and NIV exert a fast toxic effect with DON being more toxic than NIV within the first hours of incubation, whereas the inverse was observed at 16 h of incubation. On the other hand, MPA and ZEN induced increased Annexin V green positive cells within several hours of incubation with higher toxicity over time. Increased Annexin V green and Cytotox red positive cells were seen for ROC only at the highest concentration tested. For ENN B, increased Annexin V green positive cells were observed only after 12 h and α- and β-ZOL did not show cytotoxic effects. Hence, mycotoxin exposure causes either severe (DON and NIV) or more limited (ZEN, ROC, MPA, and ENN B) risk of bovine intestinal epithelial damage.
{"title":"Exploratory real-time kinetic analysis of the cytotoxicity induced by maize silage mycotoxins in a calf intestinal epithelial cell line","authors":"Sandra Debevere, K. Demeyere, N. Reisinger, J. Faas, G. Haesaert, V. Fievez, S. Croubels, E. Meyer","doi":"10.3920/WMJ2020.2651","DOIUrl":"https://doi.org/10.3920/WMJ2020.2651","url":null,"abstract":"In a temperate climate, the mycotoxins deoxynivalenol (DON), nivalenol (NIV), enniatin B (ENN B), mycophenolic acid (MPA), roquefortine C (ROC) and zearalenone (ZEN) are often found in maize silage. Although rumen microbiota are able to degrade some mycotoxins (e.g. DON), others are known to stay mainly intact (e.g. ROC). In addition, mycotoxin degradation can be hampered by a low ruminal pH or decrease in rumen microbial activity. Hence, these mycotoxins can reach the small intestine and exert a cytotoxic effect on intestinal epithelial cells. In this study, a real-time kinetic analysis of the cytotoxicity of these six mycotoxins and some of their metabolites (α- and β-zearalenol, α- and β-ZOL) was performed in a calf small intestinal epithelial cell line (CIEB). Confluency as well as the cell death parameters apoptosis and necrosis were determined to evaluate the mycotoxin-induced cytotoxicity. A combination of Annexin-V green and Cytotox red staining was used to determine early and late apoptosis as well as necrosis. Six different concentrations were tested ranging from 0.78 to 12.5 μM. Compared to cells not exposed to mycotoxins, DON and NIV exert a fast toxic effect with DON being more toxic than NIV within the first hours of incubation, whereas the inverse was observed at 16 h of incubation. On the other hand, MPA and ZEN induced increased Annexin V green positive cells within several hours of incubation with higher toxicity over time. Increased Annexin V green and Cytotox red positive cells were seen for ROC only at the highest concentration tested. For ENN B, increased Annexin V green positive cells were observed only after 12 h and α- and β-ZOL did not show cytotoxic effects. Hence, mycotoxin exposure causes either severe (DON and NIV) or more limited (ZEN, ROC, MPA, and ENN B) risk of bovine intestinal epithelial damage.","PeriodicalId":23844,"journal":{"name":"World Mycotoxin Journal","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47863924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Mesfin, K. Tesfamariam, T. Belachew, S. D. Saeger, C. Lachat, M. Boevre
Multi-mycotoxin exposure data are missing to guide risk assessment and legislation in Ethiopia. This study therefore aimed to determine mycotoxin contamination levels in maize samples from 176 rand...
{"title":"Multi-mycotoxin profiling in maize reveals prevalence of Fusarium mycotoxins in South and West Ethiopia","authors":"A. Mesfin, K. Tesfamariam, T. Belachew, S. D. Saeger, C. Lachat, M. Boevre","doi":"10.3920/WMJ2020.2645","DOIUrl":"https://doi.org/10.3920/WMJ2020.2645","url":null,"abstract":"Multi-mycotoxin exposure data are missing to guide risk assessment and legislation in Ethiopia. This study therefore aimed to determine mycotoxin contamination levels in maize samples from 176 rand...","PeriodicalId":23844,"journal":{"name":"World Mycotoxin Journal","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47483126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Pinto, A. Santos, E. Vargas, F. Madureira, A. Faria, R. Augusti
Plant-based beverages (popularly known as vegetable milk) have become increasingly important in recent years. However, the nonexistence of information on mycotoxin contamination is noticeable. We h...
{"title":"Validation of an analytical method based on QuEChERS and LC-MS/MS to quantify nine mycotoxins in plant-based milk","authors":"L. Pinto, A. Santos, E. Vargas, F. Madureira, A. Faria, R. Augusti","doi":"10.3920/WMJ2020.2656","DOIUrl":"https://doi.org/10.3920/WMJ2020.2656","url":null,"abstract":"Plant-based beverages (popularly known as vegetable milk) have become increasingly important in recent years. However, the nonexistence of information on mycotoxin contamination is noticeable. We h...","PeriodicalId":23844,"journal":{"name":"World Mycotoxin Journal","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47208500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R.E.E. Pinheiro, A. Rodrigues, E. Batista, A. Monte, M. N. Ribeiro, R. Calvet, C. Pereyra, A. Torres, M. Araripe, M. Muratori
The objective of this study was to evaluate the effects of the addition of Saccharomyces cerevisiae to feed contaminated with aflatoxin B1 (AFB1) on the performance and health of tambaqui fingerlin...
{"title":"Effect of Saccharomyces cerevisiae addition to feed contaminated with aflatoxin B1 on the health and performance indices of tambaqui (Colossoma macropomum) fingerlings","authors":"R.E.E. Pinheiro, A. Rodrigues, E. Batista, A. Monte, M. N. Ribeiro, R. Calvet, C. Pereyra, A. Torres, M. Araripe, M. Muratori","doi":"10.3920/WMJ2020.2625","DOIUrl":"https://doi.org/10.3920/WMJ2020.2625","url":null,"abstract":"The objective of this study was to evaluate the effects of the addition of Saccharomyces cerevisiae to feed contaminated with aflatoxin B1 (AFB1) on the performance and health of tambaqui fingerlin...","PeriodicalId":23844,"journal":{"name":"World Mycotoxin Journal","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47209374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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