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Курский научно-практический вестник «Человек и его здоровье»最新文献

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EVALUATION OF THE STATE OF THE OPERATIONAL EFFICIENCY OF TIMBER TRUCKS WITH RELEASE TRAILERS 带释放挂车的木材运输车作业效率状态评价
V. Posmetev, V. Nikonov
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引用次数: 0
Physiological mechanisms of action of vitamin D in oral tissues and organs and the possibility of its use in preventive dentistry (literature review) 维生素D在口腔组织器官中的生理作用机制及其在预防性牙科中的应用前景(文献综述)
N. G. Sarkisyan, E. Gaisina, M. Dobrinskaya, Arina D. Pototskaya
Vitamin D has a variety of effects on oral tissues and organs. Cholecalciferol is involved in the processes of formation of enamel and dentin, metabolism of jaw bone tissue, local immunity and antitumor reactions. The functional features of the vitamin D effects reveal the possibility of dental pathology prevention. Objective. To study the literature data on the effect of vitamin D on oral tissues and organs and the possibility of using vitamin D as a drug in the prevention of dental diseases. Materials and methods. The review and analysis of literary sources was carried out by keywords on the electronic resources of the Scopus, Web of Science, MedLine, The Cochrane Library, RSCI databases. Russian and foreign sources were used. The literature review was conducted between August 2021 and March 2022. Results. Randomized studies prove that receptors for vitamin D (colecalciferol) are found on the surface of almost all cells, which explains the pleiotropic effect of vitamin D on the human body. Colecalciferol is involved in the formation of substitutive dentin in the foci of demineralization. The active metabolite of vitamin D has an antitumor effect on the oral tissues, anti-inflammatory and antimicrobial action in periodontal disease. Colecalciferol influences osseointegration during implantation, the processes of osteogenesis and osteolysis during orthodontic treatment. Conclusion. Vitamin D has effects on various tissues and organs of the oral cavity, which gives the possibility to include cholecalciferol in clinical guidelines for dental diseases prophylaxis.
维生素D对口腔组织和器官有多种作用。胆骨化醇参与牙釉质和牙本质的形成、颌骨组织的代谢、局部免疫和抗肿瘤反应等过程。维生素D作用的功能特点揭示了预防口腔病理的可能性。目标。研究维生素D对口腔组织器官影响的文献资料,探讨维生素D作为药物预防口腔疾病的可能性。材料和方法。文献来源通过Scopus、Web of Science、MedLine、The Cochrane Library、RSCI等电子资源的关键词进行综述和分析。使用了俄罗斯和国外的资料。文献综述是在2021年8月至2022年3月期间进行的。结果。随机研究证明,几乎所有细胞的表面都存在维生素D(集骨化醇)受体,这就解释了维生素D对人体的多效性。骨化醇参与脱矿灶中替代牙本质的形成。维生素D的活性代谢物对口腔组织有抗肿瘤作用,对牙周病有抗炎、抗菌作用。骨化醇影响种植期间的骨整合,正畸治疗期间的成骨和骨溶解过程。结论。维生素D对口腔的各种组织和器官都有影响,这就有可能将胆钙化醇纳入牙科疾病预防的临床指南。
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引用次数: 0
Психолого-педагогические условия приобщения к здоровому образу жизни детей школьного возраста в рамках проекта «Укрепление и сохранение здоровья детей, вовлечение учащихся в систематические занятия физической культурой во вне-урочное время» 在“加强和保护儿童健康、让学生在课外活动中参与系统的体育活动”的框架内,为学龄儿童提供健康的教育条件
N. Maksimova
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引用次数: 0
SUBSTANTIATION OF THE TECHNOLOGY OF DIAGNOSTICS OF VEHICLE TRANSMISSION 车辆传动系统诊断技术的验证
V. I. Vergun
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引用次数: 0
Работа социального педагога по профилактике агрессивного поведения подростков в условиях общеобразовательной школы 社会教师的工作是在公立学校中预防青少年的攻击性行为。
Aiiina Ivanova, R. Gerasimova
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引用次数: 1
METHOD OF TESTING FOR WEAR DURING PLANE-PARALLEL MOVEMENT 平面平行运动磨损试验方法
V. Bukhtoyarov, V. Ivannikov, A. Golev, I.O. Kashirin
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引用次数: 0
Morphoscopic and morphometric characteristics of the LV-SI intervertebral disc in young and middle-aged individuals 中青年中LV-SI椎间盘的形态学和形态计量学特征
Maksim A. Priymak, Aleksey I. Gaivoronsky, I. V. Gaivoronsky, G. I. Nichiporuk, I. A. Goryacheva, M. G. Gaivoronskaya
Objective: to study the morphoscopic and morphometric characteristics of the LV-SI intervertebral disc according to magnetic resonance imaging. Materials and methods. The analysis of magnetic resonance imaging of 90 patients (66 men, 24 women) who did not have diseases of the lumbar spine was performed. Various morphometric parameters of the intervertebral disc (IVD) and nucleus pulposus (NP) at the LV-SI level were measured using software for processing images created on an MRI machine. The obtained data were compared between men and women, asthenics, normosthenics, hypersthenics and young (from 18 to 44 years old) and middle-aged (from 45 to 60 years old) people. In addition, morphoscopic characteristics were studied: the shape of the IVD and NP in the axial plane. Results. It was found that in normal IVD LV-SI is most often represented by elliptical (54,5%) less often kidney-shaped (45,5%) forms. Normally, the NP has an oval (57,8%) and kidney-shaped (42,2%) shape. It was shown that in men, the dorsal height of the IVD, its width, anteroposterior size, square as well as the longitudinal-transverse index of the NP were significantly higher. It has been proven that there are no significant differences in the shape of the IVD between asthenics, normo- and hypersthenics, while the height of the IVD in the center, its ventral, dorsal heights and most lateral IVD height are significantly greater in hypersthenics. It has been proved that the kidney-shaped form of NP was significantly more common in asthenics, and the oval form - in hypersthenics, while the morphometric parameters of NP did not significantly differ between extreme body types. A tendency to a decrease in IVD height in middle-aged people compared to young people was shown. Conclusion. The results obtained are necessary when planning the operation, as well as for the manufacture of rigid implants and artificial discs for arthroplasty and interbody fusion.
目的:利用磁共振成像技术研究LV-SI椎间盘的形态学和形态计量学特征。材料和方法。对90例无腰椎疾病的患者(男66例,女24例)进行磁共振成像分析。椎间盘(IVD)和髓核(NP)在LV-SI水平上的各种形态测量参数使用软件进行测量,该软件用于处理在MRI机器上生成的图像。所获得的数据在男性和女性、健美操者、健美操者、健美操者以及年轻人(18岁至44岁)和中年人(45岁至60岁)之间进行了比较。此外,还研究了形态学特征:IVD和NP在轴向面的形状。结果。我们发现,在正常的IVD中,LV-SI最常表现为椭圆形(54,5%),较少表现为肾形(45,5%)。正常情况下,NP呈椭圆形(57.8%)和肾形(42.2%)。结果表明,男性IVD的背高、宽度、前后大小、方度以及NP的纵横指数均显著高于男性。研究证明,在虚弱、正常和高压下,IVD的形状没有显著差异,而高压下,IVD的中心高度、腹侧高度、背侧高度和大部分侧侧高度明显更大。已经证明,NP的肾形形态在衰弱中更为常见,而椭圆形形态在高压中更为常见,而NP的形态计量参数在极端体型之间没有显著差异。研究显示,与年轻人相比,中年人的IVD高度有下降的趋势。结论。所获得的结果对于计划手术,以及制造用于关节置换术和椎间融合的刚性植入物和人工椎间盘是必要的。
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引用次数: 0
Use of complex medications to treat patients with back pain 使用复杂的药物来治疗背痛患者
Shuteeva Elena Yu., Krapiva Anna B., Shuteeva Tatiana V.
Purpose of the study: to assess the dynamics of pain indicators and various characteristics of the quality of life in patients with back pain when using a one-course treatment complex with the use of Clodifen Neuro. Materials and methods. The study included men and women aged 44 to 52 years with complaints of lower back pain caused by exacerbation of chronic dorsalgia. The main group included 30 patients (14 men and 16 women). The control group consisted of 24 patients (12 men and 12 women). The groups were comparable in terms of the severity of symptoms and the length of the disease. All patients received muscle relaxants and gastroprotectors of the corresponding pharmacological groups, patients in the main group received Clodifen Neuro 1 capsule twice a day for 2 weeks, patients in the control group received diclofenac tablets (enteric form) 50 mg twice a day. The effectiveness of therapy was assessed using the VAS scale and the Oswestry questionnaire. Assessment of the condition of patients in both groups was carried out before the start of the study, after the end of treatment (after 14 days) and 2 months after the end of therapy. Results. The study of the effectiveness of the use of Clodifen Neuro showed that in patients with chronic back pain, the drug favored a decrease in pain syndrome, an increase in the mobility of the spine, and the functional potential of patients. Conclusion. Treatment with Clodifen Neuro for 14 days (1 capsule orally 2 times a day) as a part of complex therapy contributed to a steady reduction in pain in the study group of patients with chronic back pain. The analgesic effect persisted for 2 months after the end of therapy. Clodifen Neuro can be recommended as a polytropic agent in the complex therapy of chronic back pain.
本研究的目的:评估腰痛患者在使用Clodifen neuroo单疗程复合治疗时疼痛指标的动态变化和生活质量的各种特征。材料和方法。研究对象包括年龄在44岁至52岁之间的男性和女性,他们的主诉是由慢性背痛加剧引起的下背部疼痛。主组30例,男14例,女16例。对照组24例,男12例,女12例。两组在症状的严重程度和疾病的持续时间方面具有可比性。所有患者均给予相应药理学组的肌肉松弛剂和胃保护剂,主组患者给予氯地芬神经1胶囊,每日2次,连用2周,对照组患者给予双氯芬酸片(肠剂型)50 mg,每日2次。采用VAS评分和Oswestry问卷评估治疗效果。两组患者的病情评估分别在研究开始前、治疗结束后(14天后)和治疗结束后2个月进行。结果。对使用Clodifen Neuro的有效性的研究表明,在慢性背痛患者中,该药物有利于减轻疼痛综合征,增加脊柱的活动能力和患者的功能潜力。结论。用Clodifen Neuro治疗14天(1粒口服,每天2次)作为综合治疗的一部分,有助于慢性背痛患者研究组疼痛的稳定减少。治疗结束后镇痛效果持续2个月。Clodifen Neuro可作为一种多效剂推荐用于慢性背痛的复杂治疗。
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引用次数: 1
BALANCE EQUATIONS FOR ROLLING WHEELS IN DRIVEN AND BRAKING MODES BASED ON LINEAR AND ANGULAR DISPLACEMENTS OF TIRE AND WHEEL POINTS 基于轮胎和车轮点线位移和角位移的驱动和制动模式下滚动车轮的平衡方程
M. Romanchenko
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引用次数: 0
Endothelial dysfunction, vascular stiffness and their correction with perindopril, losartan in patients with ischemic heart disease, arterial hypertension and chronic kidney disease after coronary stenting 缺血性心脏病、动脉性高血压和慢性肾病患者冠状动脉支架植入术后内皮功能障碍、血管僵硬及其培哚普利、氯沙坦的矫正
Nadezda N. Pribylova, Margarita V. Yakovleva, S. A. Pribylov, G. Mal, V. S. Pribylov, T. A. Barbashina
Objective. To study the state of arterial stiffness and endothelial function in patients with coronary heart disease (CHD), arterial hypertension (AH) in combination with chronic kidney disease (CKD) and to determine the effect of Perindopril and Losartan therapy on these indices including after coronary stenting. Materials and Methods. The study involved 73 patients with coronary heart disease (CHD), AH and CHD stage 2-3a. The comparison group consisted of 30 patients with CHD and AH without renal pathology. Patients with CKD were divided into 3 subgroups: the 1st - on conservative therapy with Perindopril 10 mg; the 2nd - with Losartan 100 mg daily; the 3rd - those who underwent coronary stenting and were treated with Perindopril 10 mg daily. Arterial stiffness, plasma levels of endothelin-1 (ET-1), metabolites of nitric oxide were assessed initially and after 12 weeks of therapy. Results. The patients with CHD and hypertension had a more severe endothelial dysfunction (ED) and more significant arterial stiffness. There was a correlation between GFR and PWV levels (r = -0.75; p = 0.001), nitric oxide levels (r = 0.58; p<0.01), ET-1 (r = -0.72; p < 0.01). After 12 weeks of therapy, all three subgroups showed a statistically significant decrease in ET-1 and vascular wall stiffness. Conclusion. Patients with CHD and AH, CKD had more profound ED and the severity of arterial stiffness. The use of Perindopril and Losartan in complex therapy resulted in a glomerular filtration rate increase, was accompanied by a corrective effect on ED and decreased arterial stiffness, especially in patients undergoing coronary stenting.
目标。研究冠心病(CHD)、动脉性高血压(AH)合并慢性肾脏疾病(CKD)患者的动脉硬度和内皮功能状况,并探讨培哚普利和氯沙坦治疗对冠状动脉支架植入术后这些指标的影响。材料与方法。该研究涉及73例冠心病(CHD)、AH和CHD 2-3a期患者。对照组为30例无肾脏病理的冠心病合并AH患者。将CKD患者分为3个亚组:第1组采用培哚普利10 mg保守治疗;第二组:每日100mg氯沙坦;第三组是接受冠状动脉支架植入术并每日服用培哚普利10mg的患者。在最初和治疗12周后评估动脉僵硬度、血浆内皮素-1 (ET-1)水平、一氧化氮代谢物。结果。冠心病合并高血压患者内皮功能障碍(ED)更严重,动脉僵硬更明显。GFR与PWV水平存在相关性(r = -0.75;P = 0.001),一氧化氮水平(r = 0.58;p<0.01), ET-1 (r = -0.72;P < 0.01)。治疗12周后,三个亚组均显示ET-1和血管壁硬度有统计学意义的降低。结论。冠心病合并AH、CKD患者有更严重的ED和动脉僵硬程度。在复合治疗中使用培哚普利和氯沙坦导致肾小球滤过率增加,并伴有ED的矫正作用和动脉僵硬度降低,特别是在接受冠状动脉支架植入术的患者中。
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Курский научно-практический вестник «Человек и его здоровье»
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