Bioelectrochemistry最新文献_第3页

From data to diagnosis: A comprehensive review of machine learning-driven wearable sensors in healthcare 从数据到诊断：医疗保健中机器学习驱动的可穿戴传感器的全面回顾

IF 4.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry

Pub Date : 2026-01-12 DOI: 10.1016/j.bioelechem.2026.109228

Meiting Zhao , Rui Liu , Shuang Jin , Binqiao Ren , Qiang Zhang

The integration of machine learning (ML) with advanced wearable sensor technologies is revolutionizing healthcare by enabling real-time, intelligent monitoring of physiological parameters such as electrocardiogram (ECG), blood glucose, and respiratory patterns. This review systematically examines the transformative potential of ML-driven biosensors across three core domains: health monitoring, early disease detection, and precision medicine. Key technological advancements—including self-optimizing sensor networks, explainable AI (XAI) architectures, and edge-computing-enabled miniaturized devices—are critically evaluated. Despite rapid progress, the translation of these technologies into clinical practice faces significant challenges, such as data standardization, algorithmic interpretability, privacy concerns, and regulatory hurdles. This paper also discusses emerging trends, including federated learning, quantum machine learning, and neural interfaces, which hold promise for overcoming these barriers. By addressing these challenges and leveraging ongoing interdisciplinary collaborations, ML-enhanced wearable systems are poised to redefine personalized medicine and proactive healthcare delivery on a global scale.

机器学习（ML）与先进的可穿戴传感器技术的集成，通过实现对心电图（ECG）、血糖和呼吸模式等生理参数的实时智能监测，正在彻底改变医疗保健。这篇综述系统地考察了机器学习驱动的生物传感器在三个核心领域的变革潜力：健康监测、早期疾病检测和精准医学。关键的技术进步——包括自优化传感器网络、可解释的人工智能（XAI）架构和支持边缘计算的小型化设备——得到了严格的评估。尽管进展迅速，但将这些技术转化为临床实践面临着重大挑战，如数据标准化、算法可解释性、隐私问题和监管障碍。本文还讨论了新兴趋势，包括联邦学习、量子机器学习和神经接口，它们有望克服这些障碍。通过应对这些挑战并利用正在进行的跨学科合作，机器学习增强的可穿戴系统准备在全球范围内重新定义个性化医疗和主动医疗保健服务。

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引用次数: 0

Cariogenic Streptococcus mutans accelerates the crevice corrosion of 316L stainless steel in simulated oral environment 龋齿变形链球菌在模拟口腔环境中加速316L不锈钢的缝隙腐蚀

IF 4.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry

Pub Date : 2026-01-12 DOI: 10.1016/j.bioelechem.2026.109227

Chunxiu Jiang , Meng Zhao , Anqing Li , Yahan Li , Pan Liu , Zhong Li , Fuhui Wang , Dake Xu

Metallic materials used in oral applications are simultaneously exposed to microbial colonization and crevices. Understanding the synergistic effects of microbiologically influenced corrosion (MIC) and crevice corrosion is essential to ensure the long-term performance and safety of dental alloys. Herein, we systematically investigated the corrosion behavior of 316L stainless steel (SS) under conditions with and without Streptococcus mutans and simulated crevices. S. mutans formed a dense biofilm on open surfaces, while looser biofilm was detected inside the crevice. Electrochemical tests, along with corrosion morphology and product analyses, demonstrated that both S. mutans and crevices independently increased the corrosion rate of 316L SS. Notably, their coexistence induced a pronounced synergistic effect, elevating the corrosion current density from 0.10 ± 0.03 μA cm⁻² (sterile, no crevice) to 4.35 ± 0.20 μA cm⁻². The most severe corrosion occurred inside the crevice, with a maximum pit depth of 3.7 μm after 14 days. Mott–Schottky analysis further confirmed that the combined effect of biofilm and crevice impaired the integrity of passive film. Based on these results and classical theory, we proposed an accelerated corrosion mechanism whereby the synergistic effect between biofilms and crevice critically accelerated the corrosion of 316L SS in the oral environment.

用于口腔应用的金属材料同时暴露于微生物定植和缝隙中。了解微生物影响腐蚀（MIC）和缝隙腐蚀的协同作用对于确保牙科合金的长期性能和安全性至关重要。在此，我们系统地研究了316L不锈钢（SS）在有和没有变形链球菌和模拟裂缝的条件下的腐蚀行为。变形链球菌在开放表面形成致密的生物膜，而在裂缝内检测到较松散的生物膜。电化学测试、腐蚀形貌和产物分析表明，变形链球菌和裂缝各自增加了316L SS的腐蚀速率，它们的共存产生了显著的协同效应，使腐蚀电流密度从0.10±0.03 μA cm−2（无菌，无裂缝）提高到4.35±0.20 μA cm−2。裂缝内部腐蚀最为严重，14天后最大腐蚀深度为3.7 μm。Mott-Schottky分析进一步证实了生物膜与缝隙的联合作用破坏了被动膜的完整性。基于这些结果和经典理论，我们提出了一种加速腐蚀机制，即生物膜和缝隙之间的协同作用临界加速了316L SS在口腔环境中的腐蚀。

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引用次数: 0

Enhanced microalgae-based microbial fuel cell performance using single-chamber photocatalyst air-cathode modification 利用单室光触媒空气阴极改性提高微藻微生物燃料电池性能

IF 4.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry

Pub Date : 2026-01-02 DOI: 10.1016/j.bioelechem.2026.109215

Hnin Thandar Myint , Yuka Yokoi , Lulu'atul Hamidatu Ulya , Chairat Treesubsuntorn , Yordkhuan Tachapermpon

To address the global challenges of fossil fuel depletion and climate change, attention has turned to alternative energy sources. Photosynthetic microalgae-based microbial fuel cells (AMFC) have emerged as a promising solution, utilizing bacteria to convert organic matter into energy. This study explores the improvement of electricity generation using single-chamber microalgae-based microbial fuel cells with a modified graphite-photocatalyst air cathode. Modified graphite air cathode using graphite-photocatalyst (TiO₂ and MnO₂) was observed to enhance greater power production. The electricity produced by the AMFC system using a 25% TiO₂-graphite mixture was the best potential air cathode, generating up to 5.56 ± 0.32 mW/m². The higher power density is also obtained using the fabrication of a photocatalyst air cathode. The fabricated air cathode electrocatalyst can play a reasonable cost material for the enriched energy recovery in the AMFC and/or other such electrochemical devices. This study also investigates the power generation performance of algal microbial fuel cells under three electrical configurations: series, parallel, and mixed connection. Parallel connection showed the greatest power density of 23.82 ± 3.72 mW/m² among them. However, mixed configuration provided balanced performance, with moderate voltage, current, and power density. From these results, connection type plays an important role in optimizing AMFC performance for specific applications.

为了应对化石燃料枯竭和气候变化带来的全球挑战，人们的注意力转向了替代能源。基于光合微藻的微生物燃料电池（AMFC）已经成为一种很有前途的解决方案，利用细菌将有机物转化为能量。本研究探索了利用单室微藻为基础的微生物燃料电池与改性石墨光触媒空气阴极的发电改进。采用石墨光催化剂（TiO2和MnO2）对石墨空气阴极进行了改性，提高了发电效率。使用25% tio2 -石墨混合物的AMFC系统产生的电能是最佳的潜在空气阴极，发电量高达5.56±0.32 mW/m2。利用光触媒空气阴极的制造也获得了更高的功率密度。所制备的空气阴极电催化剂可以作为AMFC和/或其他此类电化学装置中富集能量回收的合理成本材料。本研究还考察了藻类微生物燃料电池在串联、并联和混合三种电态下的发电性能。并联的功率密度最高，为23.82±3.72 mW/m2。然而，混合配置提供了平衡的性能，具有适中的电压，电流和功率密度。从这些结果来看，连接类型在优化特定应用程序的AMFC性能方面起着重要作用。

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引用次数: 0

Time-resolved, label-free electrochemical monitoring of neurotoxicity via differential pulse voltammetry 通过差分脉冲伏安法进行时间分辨、无标记的神经毒性电化学监测

IF 4.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry

Pub Date : 2026-01-02 DOI: 10.1016/j.bioelechem.2025.109214

Hasret Turkmen , Mustafa Şen

Neurotoxicity assessment is crucial for ensuring the safety of pharmaceuticals and chemicals while protecting public health by identifying hazardous substances. Here, a simple and innovative electrochemical neurotoxicity assay was presented using a screen-printed carbon electrode (SPCE) integrated petri dish platform. This system serves as a rapid, quantitative, and time-resolved alternative to standard neurotoxicity assays such as the MTT assay (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) test and is particularly suited for drug development studies. Briefly, the surface of SPCEs were modified with poly-l-lysine (PLL) to enhance both the electrochemical signal and the adherence of human neuroblastoma (SH-SY5Y) cells. Electrochemical measurements were taken in 0.5 mM [Fe(CN)₆]^3−/4− whose non-toxic effect was confirmed, and a good relationship was observed between electrochemical signal and cell viability. The electrochemical platform was then successfully tested to assess the toxic effects of H₂O₂ and doxorubicin. These findings demonstrate the platform's potential for routine electrochemical neurotoxicity evaluation and emphasize the feasibility of using a cell-based analytical system for toxicity screening applications.

神经毒性评估对于确保药品和化学品的安全，同时通过识别有害物质保护公众健康至关重要。本文采用丝网印刷碳电极（SPCE）集成培养皿平台，提出了一种简单而创新的电化学神经毒性检测方法。该系统可作为标准神经毒性测定(如MTT测定（3-（4,5-二甲基噻唑-2-基）-2,5-二苯基溴化四唑）试验的快速、定量和时间分辨替代方法，特别适用于药物开发研究。简单地说，用聚赖氨酸（PLL）修饰SPCEs表面，增强了人神经母细胞瘤（SH-SY5Y）细胞的电化学信号和粘附性。在0.5 mM [Fe(CN)6]3−/4−中进行了电化学测量，证实了其无毒作用，并观察到电化学信号与细胞活力之间存在良好的关系。然后成功地测试了电化学平台，以评估H2O2和阿霉素的毒性作用。这些发现证明了该平台在常规电化学神经毒性评估方面的潜力，并强调了使用基于细胞的分析系统进行毒性筛选应用的可行性。

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引用次数: 0

Phage-based dual-mode sensor using ECL and EIS for sensitive detection of Pseudomonas Aeruginosa 基于噬菌体的ECL和EIS双模传感器对铜绿假单胞菌的灵敏检测

IF 4.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry

Pub Date : 2025-12-31 DOI: 10.1016/j.bioelechem.2025.109212

Maryam Allahyari , Emre Dokuzparmak , Arzum Erdem , Alper AKKAYA , Bahattin Tanyolac

Pseudomonas aeruginosa is a major pathogen responsible for severe infections, particularly in immunocompromised patients and those with chronic conditions. Its increasing resistance to antibiotics underscores the urgent need for effective detection systems. This study introduces a novel biosensor based on bacteriophage (M-PAP1) in combination with MWCNT-COOH modified SPE and its application for the sensitive identification of Pseudomonas aeruginosa. The phage provides high specificity and strong target binding, while the combined ECL and EIS modes offer complementary signal outputs, enhancing analytical reliability and reducing false responses. The ECL sensor achieved LoD of 0.755 CFU ml⁻¹and demonstrated a broad linear working range of 2.28 to 10¹⁰ CFU ml⁻¹ (R²: 0.9981). In artificial urine samples, the sensor demonstrated a recovery rate of 92% to 97%, indicating its effectiveness in real biological matrices. The dual functionality for both ECL and EIS measurements highlights the system's versatility and potential for real-time clinical applications. The system also exhibited exceptional selectivity and minimal interference from non-specific bacteria such as Escherichia coli and Pseudomonas putida and Pseudomonas fluorescens. Overall, the dual-mode strategy significantly strengthens diagnostic accuracy by enabling cross-validated detection signals, offering a robust platform for rapid monitoring of P. aeruginosa in the context of rising antimicrobial resistance.

铜绿假单胞菌是造成严重感染的主要病原体，特别是在免疫功能低下患者和慢性病患者中。它对抗生素的耐药性日益增加，这突出表明迫切需要有效的检测系统。本研究介绍了一种基于噬菌体（M-PAP1）结合MWCNT-COOH修饰的SPE的新型生物传感器及其在铜绿假单胞菌敏感鉴定中的应用。噬菌体具有高特异性和强靶标结合性，而ECL和EIS结合模式提供互补的信号输出，提高了分析可靠性，减少了错误反应。ECL传感器的LoD为0.755 CFU ml - 1，线性工作范围为2.28至1010 CFU ml - 1 （R2: 0.9981）。在人工尿液样本中，该传感器的回收率为92%至97%，表明其在真实生物基质中的有效性。ECL和EIS测量的双重功能突出了系统的多功能性和实时临床应用的潜力。该系统还表现出卓越的选择性和最小的干扰非特异性细菌，如大肠杆菌、恶臭假单胞菌和荧光假单胞菌。总体而言，双模式策略通过启用交叉验证的检测信号显着增强了诊断准确性，为在抗菌素耐药性上升的背景下快速监测铜绿假单胞菌提供了一个强大的平台。

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引用次数: 0

Examination of influence of microfluidic flow and antibody orientation on biosensor performance: A case study with CA125 electrochemical biosensor 微流体流动和抗体取向对生物传感器性能影响的研究——以CA125电化学生物传感器为例

IF 4.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry

Pub Date : 2025-12-31 DOI: 10.1016/j.bioelechem.2025.109213

Neelam Vishwakarma , Shubham Kumar Patial , Mayank Garg , Suman Singh

Ovarian cancer has always posed a challenge to the healthcare industry due to a lack of early diagnosis methods, attributed to the absence of identifiable symptoms, thereby earning it the name “silent killer”. Even though the traditional diagnostic methods provide some diagnostic capabilities, they still face several bottlenecks, highlighting the need to develop a robust, sensitive and accurate biosensor, specific to ovarian cancer biomarkers. In this study, an electrochemical platform with the microfluidic method of sample introduction was analyzed to detect cancer antigen 125 (CA125), a prominent biomarker in ovarian cancer patients. The platform was decorated with alkylamine-functionalized graphene sheets (A_fGSs) and antibody aligner to act as bio-conjugation and signal-enhancing agents. Thorough structural and functionalization characterizations of the nanomaterial and sensing platform were performed. The study presents a detailed comparison of the performance of both static (drop-cast) and microfluidic sensing platforms for CA125 biomarker concentrations in the 0.0001–1000 U/mL range, with a Limit of Detection (LoD) of 6.17 μU/mL for microfluidic systems and 2.67 μU/mL for static systems.

由于缺乏可识别的症状，缺乏早期诊断方法，卵巢癌一直对医疗保健行业构成挑战，因此获得了“沉默杀手”的称号。尽管传统的诊断方法提供了一些诊断能力，但它们仍然面临着一些瓶颈，这突出了开发一种强大、敏感和准确的生物传感器，专门针对卵巢癌生物标志物的需求。本研究采用微流控进样的电化学平台检测卵巢癌患者的重要生物标志物癌抗原125 （CA125）。该平台采用烷基胺功能化石墨烯片（afgs）和抗体对准剂作为生物偶联剂和信号增强剂。对纳米材料和传感平台进行了全面的结构和功能化表征。本研究详细比较了静态（滴投）和微流控检测平台在0.0001 ~ 1000 U/mL范围内检测CA125生物标志物的性能，微流控系统的检测限为6.17 μU/mL，静态系统的检测限为2.67 μU/mL。

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引用次数: 0

Critical perspectives on thermally-drawn multimaterial and multifunctional fiber-based neural interface for neurochemical sensing and modulation 热拉多材料和多功能纤维神经接口在神经化学传感和调制中的关键观点

IF 4.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry

Pub Date : 2025-12-29 DOI: 10.1016/j.bioelechem.2025.109208

Adrijana Savevska , Yuanyuan Guo

Advanced healthcare and biomedical research require innovative approaches in the design and integration of materials for next-generation implantable biomedical devices. Recently, thermally drawn multimaterial and multifunctional fibers have been developed, which have significantly advanced biomedical implants with multifunctionality, miniaturization, and mechanical compliance with biological tissue. However, advances in their capabilities, particularly in vivo electrochemical sensing and modulation, remain limited. This review aims to bridge the gap between electrochemical sensing, thermally drawn fiber technology, and neurochemical monitoring and modulation. Recent advances in fiber-based electrochemical sensors are highlighted, with a focus on material selection, surface modification methods, and detection techniques. Despite significant progress in this interdisciplinary field, challenges persist in ensuring the long-term stability, biocompatibility, and scalability of these sensors within complex physiological environments such as the brain. In addition to mentioning the current limitations, we emphasize the potential of fiber probes to elevate fundamental life-science research and clinical diagnostics to a new level.

先进的医疗保健和生物医学研究需要创新的方法来设计和集成下一代植入式生物医学设备的材料。近年来，热拉伸多材料和多功能纤维的发展，极大地推动了生物医学植入物的多功能性、小型化和与生物组织的机械顺应性。然而，它们的能力，特别是在体内电化学传感和调制方面的进步仍然有限。本文旨在弥合电化学传感、热拉伸纤维技术和神经化学监测与调制之间的差距。重点介绍了纤维基电化学传感器的最新进展，重点介绍了材料选择、表面改性方法和检测技术。尽管这一跨学科领域取得了重大进展，但在确保这些传感器在复杂生理环境（如大脑）中的长期稳定性、生物相容性和可扩展性方面仍然存在挑战。除了提到目前的局限性外，我们还强调了纤维探针将基础生命科学研究和临床诊断提升到一个新水平的潜力。

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引用次数: 0

A dual-signal electrochemical aptasensor based on rGO@MoS2-Fc nanozyme for sensitive detection of low-density lipoprotein 基于rGO@MoS2-Fc纳米酶的双信号电化学感应传感器用于低密度脂蛋白的灵敏检测

IF 4.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry

Pub Date : 2025-12-24 DOI: 10.1016/j.bioelechem.2025.109206

Zhide Zhou , Haimei Li , Xiaohua Deng , Yuxuan Shi , Jiahang Huang , Yu Zhou , Xiaohong Tan , Jintao Liang , Guiyin Li

Cardiovascular disease (CVD) is the leading cause of death worldwide, particularly in the developing countries. Low-density lipoprotein (LDL), a critical biomarker for the early detection and intervention of CVD, provides valuable diagnostic and prognostic information for CVD. Herein, we developed a dual-signal electrochemical aptasensor for LDL detection based on a peroxidase-like nanozyme composed of reduced graphene oxide@molybdenum disulfide-ferrocenecarboxylic acid (rGO@MoS₂-Fc). In the process of electrochemical testing, rGO@MoS₂-Fc achieved the synergistic amplification of electrochemical signals both an enhanced Fc oxidation current detected by differential pulse voltammetry (DPV), and an increased hydrogen peroxide (H₂O₂) decomposition current via amperometric current-time (i-t) analysis. The DPV signal, corresponding to Fc oxidation, exhibited a logarithmic linear response over a broad LDL concentration ranged from 0.001 to 100.0 μg/mL, with a limit of detection (LOD) as low as 0.91 ng/mL. Meanwhile, the i-t signal, arising from H₂O₂ decomposition, displayed a linear range of 1.0 to 80.0 μg/mL and an LOD of 0.80 μg/mL. This dual-signal strategy exhibited good selectivity, reproducibility, stability and self-calibration capability. Analysis of human serum samples showed that the proposed strategy is expected to be a powerful method for early-stage CVD diagnosis and clinical management.

心血管疾病（CVD）是全世界，特别是发展中国家的主要死亡原因。低密度脂蛋白（LDL）是CVD早期检测和干预的重要生物标志物，为CVD的诊断和预后提供了有价值的信息。在此，我们基于还原石墨烯oxide@molybdenum二硫化二茂铁羧酸（rGO@MoS2-Fc）组成的过氧化物酶类纳米酶开发了一种用于LDL检测的双信号电化学感应传感器。在电化学测试过程中，rGO@MoS2-Fc实现了电化学信号的协同放大，通过差分脉冲伏安法（DPV）检测Fc氧化电流增强，通过电流-时间（i-t）分析实现过氧化氢（H2O2）分解电流增加。与Fc氧化反应相对应的DPV信号在0.001 ~ 100.0 μg/mL范围内呈对数线性响应，检出限低至0.91 ng/mL。H2O2分解产生的i-t信号线性范围为1.0 ~ 80.0 μg/mL， LOD为0.80 μg/mL。该双信号策略具有良好的选择性、重复性、稳定性和自校准能力。对人血清样本的分析表明，该策略有望成为早期CVD诊断和临床管理的有力方法。

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引用次数: 0

MFC-based biosensors for real-time monitoring BOD and Toxicity in paraquat and pesticide-contaminated wastewater 基于mfc的生物传感器用于实时监测百草枯和农药污染废水中的BOD和毒性

IF 4.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry

Pub Date : 2025-12-24 DOI: 10.1016/j.bioelechem.2025.109210

Raqba Raqba , Azka Azfreen , Warda Imran , Muhammad Usman , Naeem Ali

Monitoring water quality is crucial for ecosystem preservation and public health in Pakistan, where agricultural/chemical contamination is diminishing clean water resources. This research aimed to develop long-term, reusable, and cost-effective MFC-based biosensors for monitoring BOD and toxicity in paraquat, pesticide-contaminated wastewater. Two double-chamber MFCs were fabricated with a 250 mL working volume, a Nafion membrane, and carbon felt electrodes, inoculated with pesticide-contaminated soil (PMFC) and pesticide-contaminated soil plus anaerobic sludge (PSMFC). Both biosensors reached a voltage of 400 ± 10 mV after 48 h, which was enhanced to 600 ± 25 mV with a 200 mV solar input during the enrichment phase. During stable power generation, PMFC and PSMFC achieved current outputs of 0.024 mA and 0.014 mA, respectively, and power densities of 225.49 mWm⁻² and 50.06 mWm⁻². PMFC (R² 0.9343) showed a stronger linear correlation between BOD levels (10–70 mgL⁻¹) and voltage than PSMFC (R² 0.7673). Voltage initially increased at paraquat concentrations of 1–10 mgL⁻¹ but decreased at 50–100 mgL⁻¹ due to biofilm inhibition. BOD measurements by PMFC closely matched conventional BOD₅ results, with a mean relative error of 7.03 %, highlighting its superior sensing performance with a 40-min response time during real-time monitoring.

监测水质对巴基斯坦的生态系统保护和公共卫生至关重要，因为巴基斯坦的农业/化学污染正在减少清洁水资源。本研究旨在开发长期、可重复使用、具有成本效益的基于mfc的生物传感器，用于监测百草枯和农药污染废水中的BOD和毒性。以250 mL工作体积、Nafion膜和碳毡电极制备了两个双室mfc，分别接种了农药污染土壤（PMFC）和农药污染土壤加厌氧污泥（PSMFC）。48 h后，两个生物传感器的电压均达到400±10 mV，在富集阶段，在200 mV的太阳能输入下，电压增强到600±25 mV。在稳定发电时，PMFC和PSMFC的输出电流分别为0.024 mA和0.014 mA，功率密度分别为225.49 mWm−2和50.06 mWm−2。PMFC （R2 0.9343）比PSMFC （R2 0.7673）显示出更强的线性相关性（10-70 mgL−1）。在百草枯浓度为1 - 10 mgL−1时，电压开始升高，但在50-100 mgL−1时，由于生物膜的抑制作用，电压下降。PMFC的BOD测量与传统的BOD₅结果密切匹配，平均相对误差为7.03%，突出了其在实时监测期间具有40分钟响应时间的优越传感性能。

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引用次数: 0

Smart nanostructured electrodes integrated with microbial fuel cells for wastewater-to-energy conversion and on-site detection of antibiotic in real wastewater 集成了微生物燃料电池的智能纳米结构电极，用于废水-能源转换和实际废水中抗生素的现场检测

IF 4.5 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry

Pub Date : 2025-12-23 DOI: 10.1016/j.bioelechem.2025.109211

Tukendra Kumar, Satya Eswari Jujjavarapu

Detection of ciprofloxacin (CIP) is crucial due to its persistence and frequent occurrence in water bodies. An algal microbial fuel cell (MFC) integrated with an electrospun carbon nanotube–polyaniline–zinc oxide (CNT–PANI–ZnO) nanofiber electrode was developed for simultaneous renewable energy generation and CIP detection. The electrode enhanced electron transfer efficiency, enabling sensitive monitoring of voltage changes during CIP analysis. The electrode properties were characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), ultraviolet–visible (UV–Vis) spectroscopy, zeta potential, and contact angle analyses. Bio-electrochemical performance was assessed using linear sweep voltammetry (LSV), cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS). The algal MFC achieved a maximum power density of 27.57 ± 0.95 mW m⁻³ at a current density of 46.73 ± 0.57 mA m⁻² with an internal resistance of 22 Ω. CIP was detected with a minimum limit of 0.5 μg L⁻¹ and a sensitivity of 0.1568 mV (μg L⁻¹)⁻¹ under stable voltage conditions. The system exhibited reusability over three operational cycles. These findings demonstrate the potential of CNT–PANI–ZnO-based algal MFCs as eco-friendly platforms for sustainable energy conversion and real-time contaminant sensing.

环丙沙星（CIP）在水体中具有持久性和高发性，对其检测具有重要意义。采用电纺丝碳纳米管-聚苯胺-氧化锌（CNT-PANI-ZnO）纳米纤维电极，研制了一种藻类微生物燃料电池（MFC），用于同步可再生能源发电和CIP检测。该电极提高了电子传递效率，能够在CIP分析过程中灵敏地监测电压变化。采用扫描电镜（SEM）、透射电镜（TEM）、x射线光电子能谱（XPS）、x射线衍射（XRD）、傅里叶变换红外光谱（FTIR）、紫外-可见（UV-Vis）光谱、zeta电位和接触角分析对电极性能进行了表征。采用线性扫描伏安法（LSV）、循环伏安法（CV）和电化学阻抗谱法（EIS）评价生物电化学性能。在电流密度为46.73±0.57 mA m−2，内阻为22 Ω的条件下，藻MFC的最大功率密度为27.57±0.95 mW m−3。在稳定电压条件下，CIP的检测下限为0.5 μg L−1，灵敏度为0.1568 mV (μg L−1)−1。该系统在三个操作周期内表现出可重用性。这些发现证明了基于cnt - pani - zno的藻类mfc作为可持续能源转换和实时污染物传感的环保平台的潜力。

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引用次数: 0