Dental Materials最新文献

{"title":"Changes in the composition and mechanical properties of dentin in mouse models of diabetes","authors":"K. Tang ,&nbsp;S. Ceteznik ,&nbsp;M. Kim ,&nbsp;K.E. Bornfeldt ,&nbsp;J.E. Kanter ,&nbsp;H. Zhang ,&nbsp;D.D. Arola","doi":"10.1016/j.dental.2024.09.010","DOIUrl":"10.1016/j.dental.2024.09.010","url":null,"abstract":"<div><h3>Objectives</h3><div>This study employed mouse models of type 1 (T1D) and type 2 (T2D) diabetes to characterize the changes in tooth dentin composition and its mechanical properties.</div></div><div><h3>Methods</h3><div>Thirty-two mice were used in this study and divided into T1D, T2D and corresponding control groups. Mandibles were extracted 12 weeks after the onset of diabetes, and dentin from the first molars was evaluated in varying regions of the root. The composition was assessed using Raman Spectroscopy. Nanoindentation and Vickers indentation were employed to study the mechanical properties of the tissue. Statistical significance was evaluated by two-way analysis of variance with respect to the diabetic group and region of the tooth (p ≤ 0.05).</div></div><div><h3>Results</h3><div>In the T2D model, the mineral-to-collagen ratio, hardness, and storage modulus of the intertubular dentin were significantly reduced compared to tissue from the controls, especially in the cervical regions of the tooth. The reduction in the mineral-to-collagen ratio was also observed in the T1D model, but changes in nanomechanical properties were not evident. However, the bulk hardness of the teeth in the T1D model was lower than in the littermate controls. Optical microscopy revealed significant wear of the tooth crowns in both models of diabetes, which appear to result from parafunctional activities.</div></div><div><h3>Conclusion</h3><div>This study suggests that both type 1 and type 2 models of diabetes are associated with detrimental changes in dentin.</div></div><div><h3>Clinical significance</h3><div>Better understanding of how diabetes affects dentin and the contributing mechanisms will be key to improving treatments for people with diabetes.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"40 11","pages":"Pages 2017-2024"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142338148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of optimized microstructured surfaces on bond strength and durability of NPJ-printed zirconia","authors":"Yuhan Ma ,&nbsp;Huihua Wang ,&nbsp;Yang Xiang ,&nbsp;Mingxing Li ,&nbsp;Dongni Shen ,&nbsp;Sisi Zhang ,&nbsp;Xiaojian Zhou ,&nbsp;Jun An ,&nbsp;Ying Shi ,&nbsp;Baiping Fu","doi":"10.1016/j.dental.2024.09.016","DOIUrl":"10.1016/j.dental.2024.09.016","url":null,"abstract":"<div><h3>Objectives</h3><div>This study was to investigate the effects of optimized microstructured surfaces on bond strength and bond durability of the latest nanoparticle jetting (NPJ)-printed zirconia.</div></div><div><h3>Methods</h3><div>Zirconia microstructured surfaces with different geometries and void volume were analyzed through three-dimensional finite element analysis for surface micromorphology optimization. Zirconia disks and cylinders were additively manufactured by an NPJ 3D printer (N = 128). They were randomly divided into four groups based on surface micromorphology optimization and airborne-particle abrasion (APA) treatment before they were bonded using 10-methacryloloxydecyl dihydrogen phosphate (MDP) containing resin cement (Clearfil SA luting cement). The shear bond strengths (SBSs) were tested before and after 10,000 thermocycles and were analyzed by one-way ANOVA analysis. Failure modes were determined by optical microscopy. Zirconia surfaces were analyzed with X-ray diffraction, scanning electron microscopy, and three-dimensional interference microscopy.</div></div><div><h3>Results</h3><div>The optimized microstructured surface was characterized by circular microstructures with 60 % void volume, about 20 µm of depths, about 10 µm of undercuts, and consistent beam widths. The optimized microstructured surface combined with APA treatment and MDP-containing resin cement possessed the highest SBSs both before and after thermocycling aging (P＜0.05). The greater reductions of zirconia bond strengths occurred when the zirconia were not treated with APA (P＜0.05).</div></div><div><h3>Significance</h3><div>The optimized microstructured zirconia surface with circular microstructures and 60 % void volume fabricated by the latest NPJ printing technology could greatly enhance the zirconia bond strength and durability in combination with APA treatment and application of MDP-containing resin cement, which might be promising for adhesively bonded indirect restorations of NPJ-printed zirconia.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"40 11","pages":"Pages 1991-1999"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142338154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colloidal platinum nanoparticles enhance resin-dentin bonding durability","authors":"Yuan Yuan ,&nbsp;Papichaya Intajak ,&nbsp;Norihito Sakaguchi ,&nbsp;Shihchun Ting ,&nbsp;Hongbo Zhang ,&nbsp;Takatsumi Ikeda ,&nbsp;Shuhei Hoshika ,&nbsp;Hidehiko Sano ,&nbsp;Atsushi Tomokiyo","doi":"10.1016/j.dental.2024.09.015","DOIUrl":"10.1016/j.dental.2024.09.015","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aims to investigate the effect of colloidal platinum nanoparticles (CPN) on the durability of resin-dentin bonding performance with contemporary adhesives.</div></div><div><h3>Methods</h3><div>Sixty non-carious human maxillary premolars were subjected to microtensile bond strength (µTBS) testing and divided into two main groups: CPN-treated and untreated. Within each group, specimens were randomly allocated to Clearfil Megabond 2 (MB2), Scotchbond Universal Plus Adhesive with self-etch mode (SE-SUP), and etch-and-rinse mode (ER-SUP) subgroups (n = 10/group). CPN was applied to dentin in the MB2 and SE-SUP groups for 20 s, followed by rinsing before adhesive application. In the ER-SUP group, CPN was applied after etch-and-rinse. The µTBS was tested after 24 h, 6 months, and 1 year, and the fracture modes were observed using SEM. The µTBS data were analyzed using a two-way ANOVA and post-hoc Tukey HSD test (α = 0.05). An additional twelve premolars underwent TEM/STEM/EDX for ultra-morphological observations.</div></div><div><h3>Results</h3><div>The application of CPN significantly prevented a decline in the µTBS of both the MB2 and SE-SUP groups. No significant decrease was observed in the ER-SUP group, either with aging or CPN application. Ultra-morphological images revealed platinum nanoparticles attaching to the collagen fibrils of the hybrid layer regardless of aging. It was highlighted that the nanoparticles attached to the banded collagen in the aging groups were observed.</div></div><div><h3>Significance</h3><div>CPN exhibits the potential in enhancing the longevity of resin-dentin bonding in SE mode.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"40 11","pages":"Pages 2034-2042"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142363690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of experimental resin composites with cholesteryl methacrylate organic matrix – Part 2","authors":"Julyana Dumas Santos Silva ,&nbsp;Letícia Nunes de Almeida ,&nbsp;Antônio Silva Machado ,&nbsp;Amanda Alves de Oliveira ,&nbsp;Luiza Santos Cardoso ,&nbsp;Cristhiane Gonçalves ,&nbsp;Isaac Yves Lopes de Macêdo ,&nbsp;Eric de Souza Gil ,&nbsp;Crisnicaw Veríssimo ,&nbsp;Karla de Aleluia Batista ,&nbsp;Luciano Morais Lião ,&nbsp;Carlos Estrela ,&nbsp;Ricardo Menegatti ,&nbsp;Lawrence Gonzaga Lopes","doi":"10.1016/j.dental.2024.07.037","DOIUrl":"10.1016/j.dental.2024.07.037","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to evaluate the degree of conversion (%), flexural strength (MPa), elastic modulus (GPa), compressive strength (MPa), Knoop microhardness (KHN), post-gel shrinkage (%) and prediction of ideal concentration of cholesteryl methacrylate (CM) in experimental resins.</div></div><div><h3>Methods</h3><div>Four formulations were manipulated (F): F1, control group, (0 % CM); F2 (15 % CM); F3 (19.8 % CM) and F4 (30 % CM). Bis-GMA and CM percentages were determined using Statistica™ software. For the degree of conversion test, Raman spectroscopy was used. To testing flexural strength, elastic modulus and compressive strength, a universal testing machine was used. For the Knoop microhardness test five indentations were made in each sample. Post-gel shrinkage was determined using the strain gauge method. Statistica™ software processed all data obtained in this study. Results were submitted to one-way ANOVA and Tukey's post hoc tests (α = 0.05).</div></div><div><h3>Results</h3><div>Better performance was observed for F2 (15 % CM) and F3 (19,8 % CM) for degree of conversion, elastic modulus and post-gel shrinkage. For Knoop microhardness F2 (15 % CM), F3 (19,8 % CM) and F4 (30 % CM) showed higher values than F1 (0 % CM). For flexural strength F1 (0 % CM) and F3 (19,8 %) were similar and F4 showed the lowest values and for compressive strength F1 (0 % CM) showed the highest values. For mixture designs analysis data, concentrations ≤ 25 % of CM would provide better results.</div></div><div><h3>Significance</h3><div>Addition of CM at concentrations lower than 30 % contributed to a significant increase in the degree of conversion, microhardness values, elastic modulus and reduction of post-gel shrinkage.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"40 11","pages":"Pages e63-e71"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141900328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving accuracy and efficiency of the machined PEEK denture based on NSGA-II integrated GABP neural network","authors":"Hao Jia ,&nbsp;Shuting Liang ,&nbsp;Ji Zhao ,&nbsp;Jingjin Li ,&nbsp;Handa Dai ,&nbsp;Shijun Ji","doi":"10.1016/j.dental.2024.07.011","DOIUrl":"10.1016/j.dental.2024.07.011","url":null,"abstract":"<div><h3>Objectives</h3><div>The polymer polyetheretherketone (PEEK) is gradually being used in dental restorations because of its excellent mechanical properties, chemical resistance, fatigue resistance, thermal stability, radiation translucency and good biocompatibility. To process PEEK dentures with lower surface roughness as quickly as possible, the non-dominated sorting genetic algorithm-II (NSGA-II) integrated genetic algorithm back propagation (GABP) neural network was proposed, which can adjust the combination of process parameters for milling PEEK dentures.</div></div><div><h3>Methods</h3><div>The PEEK machining was conducted using a four-axis dental milling machine at different process parameters. The surface roughness of PEEK dentures was characterized using surface roughness profiler and scanning electron microscopy (SEM). The optimum machining performance of milling PEEK dentures was investigated using a multi-objective optimization model named as NSGA-II integrated GABP neural network algorithm. The surface roughness (Ra) and material removal rate (MRR) were used as optimization objectives.</div></div><div><h3>Results</h3><div>The multi-objective optimization model effectively improved surface roughness and machining efficiency for milling PEEK dentures. The validation experiments showed that the surface roughness of all PEEK dentures was less than 0.2<span><math><mrow><mi>μ</mi><mi>m</mi></mrow></math></span>, which was within the range of surface roughness set in this paper. The GABP surface roughness prediction model had an average error of 6 %. For the same surface roughness value, the optimized milling parameters all had a greater material removal rate.</div></div><div><h3>Significance</h3><div>The research results can improve current PEEK denture CAD/CAM technology by providing appropriate milling parameters using NSGA-II integrated GABP algorithm.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"40 11","pages":"Pages e82-e94"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141911015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging technologies for the evaluation of spatio-temporal polymerisation changes in flowable vs. sculptable dental resin-based composites","authors":"Danijela Marovic ,&nbsp;Håvard J. Haugen ,&nbsp;Matej Par ,&nbsp;Stefanie Linskens ,&nbsp;Emile Mensikova ,&nbsp;Visnja Negovetic Mandic ,&nbsp;Sander Leeuwenburgh ,&nbsp;Liebert P. Nogueira ,&nbsp;Pekka K. Vallittu ,&nbsp;Qianli Ma","doi":"10.1016/j.dental.2024.09.002","DOIUrl":"10.1016/j.dental.2024.09.002","url":null,"abstract":"<div><h3>Background</h3><div>This study presents a novel multi-technique approach that integrates micro-CT and optical photothermal infrared spectroscopy (O-PTIR) to evaluate polymerisation differences, so-called spatio-temporal polymerisation properties, between flowable and sculptable dental resin-based composites.</div></div><div><h3>Methods</h3><div>Ten commercially available dental composites were investigated, including flowable and sculptable counterparts from the same manufacturer. Eight parameters were evaluated: short-term polymerisation characteristics (degree of conversion after 5 min, maximum polymerisation rate, time to reach maximum polymerisation rate) was measured using ATR-FTIR with real-time monitoring; changes in the degree of conversion with depth were evaluated with O-PTIR, 3D visualisation of shrinkage patterns, overall volumetric shrinkage, depth-specific shrinkage, and porosity were measured using micro-CT; surface morphology with detailed measurements of elemental composition was characterised using SEM/EDX; light transmittance was analysed with a NIST-referenced spectrometer.</div></div><div><h3>Results</h3><div>The study found that the increase in filler weight and volume ratio reduced the degree of conversion and polymerisation shrinkage, while moderately influencing the maximum polymerisation rates. The time to reach maximum polymerisation rates and light transmittance were not dependent on the filler amount. O-PTIR assessed a depth-dependent decrease in the degree of conversion for both composite types, with flowable composites generally showing a greater decrease in the degree of conversion than sculptable composites, except for bulk-fill composites. Micro-CT scans showed significantly higher flowable shrinkage values than their sculptable counterparts, highlighting the performance differences between the two types of composites.</div></div><div><h3>Conclusions</h3><div>The findings of this study have practical implications for the selection and use of dental composites. Flowable composites, despite their higher degrees of conversion and polymerisation rates, also exhibit higher volumetric shrinkage, which can be detrimental for clinical applications. The new measurement methods used in this study provide a comprehensive overview of the polymerisation behaviour of commercially available dental composites, offering valuable insights for material optimisation.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"40 11","pages":"Pages 1895-1908"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142277761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct ink writing with dental composites: A paradigm shift toward sustainable chair-side production","authors":"Po-Chun Tseng ,&nbsp;Dar-Bin Shieh ,&nbsp;Andreas Kessler ,&nbsp;Dalia Kaisarly ,&nbsp;Peter Rösch ,&nbsp;Karl-Heinz Kunzelmann","doi":"10.1016/j.dental.2024.08.002","DOIUrl":"10.1016/j.dental.2024.08.002","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the dimensional accuracy of occlusal veneers printed using a novel direct ink writing (DIW) system and a clinically approved dental composite.</div></div><div><h3>Methods</h3><div>A novel three-dimensional printer was developed based on the extrusion-based DIW principle. The printer, constructed primarily with open-source hardware, was calibrated to print with a flowable resin composite (Beautifil Flow Plus). The feasibility of this technology was assessed through an evaluation of the dimensional accuracy of 20 printed occlusal veneers using a laboratory confocal scanner. The precision was determined by pairwise superimposition of the 20 prints, resulting in a set of 190 deviation maps used to evaluate between-sample variations.</div></div><div><h3>Results</h3><div>Without material waste or residuals, the DIW system can print a solid occlusal veneer of a maxillary molar within a 20-minute timeframe. Across all the sampled surface points, the overall unsigned dimensional deviation was 30.1 ± 20.2 µm (mean ± standard deviation), with a median of 24.4 µm (interquartile range of 22.5 µm) and a root mean square value of 36.3 µm. The pairwise superimposition procedure revealed a mean between-sample dimensional deviation of 26.7 ± 4.5 µm (mean ± standard deviation; n = 190 pairs), indicating adequate precision. Visualization of the deviation together with the nonextrusion movements highlights the correlation between high-deviation regions and material stringing.</div></div><div><h3>Significance</h3><div>This study underscores the potential of using the proposed DIW system to create indirect restorations utilizing clinically approved flowable resin composites. Future optimization holds promise for enhancing the printing accuracy and increasing the printing speed.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"40 11","pages":"Pages 1753-1761"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141900329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel matrix formulation for resin composite: Chemical and biomechanical characterization – Part 1","authors":"Julyana Dumas Santos Silva ,&nbsp;Letícia Nunes de Almeida ,&nbsp;Antônio Silva Machado ,&nbsp;Érica Miranda de Torres ,&nbsp;Eric de Souza Gil ,&nbsp;Cristhiane Gonçalves ,&nbsp;Luciano Morais Lião ,&nbsp;Germán Sanz Lobón ,&nbsp;Boniek Gontijo Vaz ,&nbsp;Lawrence Gonzaga Lopes ,&nbsp;Ricardo Menegatti","doi":"10.1016/j.dental.2024.07.032","DOIUrl":"10.1016/j.dental.2024.07.032","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the effects of adding cholesteryl methacrylate (CM) monomer to experimental composite resins and evaluate its impact on polymerization shrinkage force (PSF), Knoop microhardness (KHN), sorption and solubility (SS), vulnerability to spontaneous oxidation (VOE), porosity (BES), viscosity (V), and cross-link density (CLD). CM was synthesized, mixed with varying proportions of Bis-GMA, 70 wt% filler particles, and 40 % TEGDMA. The groups tested were: CM0 (60 % Bis-GMA), CM6 (54 % Bis-GMA/6 % CM), CM12 (48 % Bis-GMA/12 % CM), CM18 (42 % Bis-GMA/18 % CM) and CM24 (36 % Bis-GMA/24 % CM). The PSF was evaluated using a universal testing machine. KHN was measured with a 50 g load for 30 s. SS was determined according to ISO 4049:2009. VOE was measured with a three-electrode system in an electrochemical cell. BES images were obtained using an electron microscope to assess porosity. Viscosity was measured through rheological analysis. CLD was estimated from hardness readings before and after ethanol storage.</div></div><div><h3>Results</h3><div>CM6 (0.34 N) and CM12 (0.34 N) exhibited the lowest PSF values compared to CM0 (0.91 N). For KHN, CM6 (32.03) and CM12 (31.03) had higher values than CM0 (25.83) and were similar to CM18 (29.39) and CM24 (28.64). SS showed no significant differences among the groups. VOE indicated low vulnerability across all groups. CM12 had greater porosity compared to CM0 in BES images. CM0 had the lowest viscosity among the groups. No differences in CLD were observed among CM0, CM12, CM18, and CM24 regarding softening effects.</div></div><div><h3>Significance</h3><div>Adding CM to Bis-GMA/TEGDMA composite resins can reduce polymerization shrinkage force and increase the initial Knoop microhardness without affecting the other properties studied.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"40 11","pages":"Pages e53-e62"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141905236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physicochemical and biological properties of dental materials and formulations with silica nanoparticles: A narrative review","authors":"Larissa Pavanello ,&nbsp;Iago Torres Cortês ,&nbsp;Rafaela Durrer Parolina de Carvalho ,&nbsp;Mayara Zaghi Dal Picolo ,&nbsp;Vanessa Cavalli ,&nbsp;Larissa Tavares Sampaio Silva ,&nbsp;Letícia Cristina Cidreira Boaro ,&nbsp;Polina Prokopovich ,&nbsp;Karina Cogo-Müller","doi":"10.1016/j.dental.2024.07.028","DOIUrl":"10.1016/j.dental.2024.07.028","url":null,"abstract":"<div><h3>Objective</h3><div>Silica nanoparticles (SNPs) have been extensively studied and used in different dental applications to promote improved physicochemical properties, high substance loading efficiency, in addition to sustained delivery of substances for therapeutic or preventive purposes. Therefore, this study aimed to review the SNPs applications in nanomaterials and nanoformulations in dentistry, discussing their effect on physicochemical properties, biocompatibility and ability to nanocarry bioactive substances.</div></div><div><h3>Data resources</h3><div>Literature searches were conducted on PubMed, Web of Science, and Scopus databases to identify studies examining the physicochemical and biological properties of dental materials and formulations containing SNPs. Data extraction was performed by one reviewer and verified by another</div></div><div><h3>Study selection</h3><div>A total of 50 were reviewed. <em>In vitro</em> studies reveal that SNPs improved the general properties of dental materials and formulations, such as microhardness, fracture toughness, flexural strength, elastic modulus and surface roughness, in addition to acting as efficient nanocarriers of substances, such as antimicrobial, osteogenic and remineralizing substances, and showed biocompatibility</div></div><div><h3>Conclusions</h3><div>SNPs are biocompatible, improve properties of dental materials and serve as effective carriers for bioactive substances</div></div><div><h3>Clinical significance</h3><div>Overall, SNPs are a promising drug delivery system that can improve dental materials biological and physicochemical and aesthetic properties, increasing their longevity and clinical performance. However, more studies are needed to elucidate SNPs short- and long-term effects in the oral cavity, mainly on in vivo and clinical studies, to prove their effectiveness and safety.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"40 11","pages":"Pages 1729-1741"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141905237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applications of smart materials in minimally invasive dentistry – some research and clinical perspectives","authors":"M. Par ,&nbsp;L. Cheng ,&nbsp;J. Camilleri ,&nbsp;P. Lingström","doi":"10.1016/j.dental.2024.09.017","DOIUrl":"10.1016/j.dental.2024.09.017","url":null,"abstract":"<div><h3>Objectives</h3><div>Dental caries is one of the most prevalent bacteria-induced non-communicable diseases globally. It is known to be the top oral health burden in both developing and developed nations. There is substantial literature on the disease process and there is still debate on the extent of caries removal needed and the adequacy of the materials available to restore the lost tooth structure. The current review discusses the disease process together with the contemporary management of the carious lesion and also presents substantial evidence on novel materials and techniques that make minimally invasive dentistry predictable.</div></div><div><h3>Methods</h3><div>The written work presented shows the most relevant literature for the management of dental caries focusing on novel materials used in minimally invasive dentistry.</div></div><div><h3>Results</h3><div>There is still much to learn about specific antimicrobial and caries prevention mechanisms of novel materials. Materials that respond to a single or a few stimuli remain \"weakly intelligent\" in the face of the complex microenvironment in the oral cavity. Engineered systems that combine artificial intelligence and chemical engineering, are expected to possess higher intelligence, self-healing capabilities as well as environmental adaptability, and may be future promising research directions.</div></div><div><h3>Significance</h3><div>The targeted approach in managing dental caries will hopefully have a better clinical outcome. The strategies discussed are alternatives to the contemporary approach and will improve the clinical management.</div></div>","PeriodicalId":298,"journal":{"name":"Dental Materials","volume":"40 11","pages":"Pages 2008-2016"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142338147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}