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SEQUELAS DENTAIS APÓS TRAUMATISMO NA DENTIÇÃO DECÍDUA: RELATO DE CASO 初级牙列创伤后的牙齿后遗症:病例报告
Pub Date : 2017-12-05 DOI: 10.17765/1518-1243.2017v19n2p127-133
Priscila Thurler de Melo, I. Reis, Gabriela Gomes Guimarães, A. F. Rey, Adílis Kalina Alexandria, Thais Rodrigues Campos Soares
Trauma in primary teeth is routine in dentistry, requiring great ability and common sense in dealing with the patient or kin. Teeth trauma may bring about sequences in primary teeth and in developing permanent ones, due to a close anatomic relationship between the primary teeth apexes and the germs of permanent teeth. Current assay forwards teeth sequelae after trauma in primary teeth in a patient without any dental treatment. A ten-year old male made a visit to the UNIVERSO dentistry clinic, without any complaints. Clinical exam revealed color change and prolonged retention of element 51 which caused an eruption deviation in the permanent successor and, consequently, previous crossed bite. Tutors confirmed trauma history at element 51 when five years old, but did not remember the manner and place of accident. They did not mention any dental treatment after the trauma. After radiographic evaluation and exam, exodonty of the deciduous element was performed and the patient was forwarded to orthodental treatment. A fixed inclined plane was executed to relocate the permanent successor. Results show that trauma causes sequelae in the primary tooth and in the permanent successor. Further, lack of treatment and follow-up may have contributed towards an eruption deviation in permanent teeth. Correction of the anterior crossed bite was successful after adequate treatment.
乳牙外伤在牙科中是常见的,在处理患者或亲属时需要很强的能力和常识。由于乳牙牙尖与恒牙的胚芽有密切的解剖关系,牙齿外伤可导致乳牙和恒牙发育中的序列。目前的分析表明,在没有任何牙科治疗的病人的乳牙创伤后的牙齿后遗症。一名10岁的男性到universso牙科诊所就诊,没有任何抱怨。临床检查发现51号元素的颜色改变和长时间的保留导致永久继位者的出牙偏差,从而导致先前的交叉咬合。导师确认了他五岁时在51号小队的创伤史,但不记得事故发生的方式和地点。他们没有提到创伤后的任何牙科治疗。经影像学评估和检查后,对乳牙进行外拔,并将患者转至正畸治疗。一个固定的斜面被用来重新安置永久的继承者。结果表明,创伤可引起原牙和恒牙的后遗症。此外,缺乏治疗和随访可能是导致恒牙萌出偏差的原因。经过适当的治疗,前交叉咬合矫正成功。
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引用次数: 0
DIFERENTES ÁREAS ADESIVAS AFETAM A RESISTÊNCIA DE UNIÃO AO MICROCISALHAMENTO 不同的粘接区域影响微剪切粘结强度
Pub Date : 2017-12-05 DOI: 10.17765/1518-1243.2017V19N2P179-185
Kevelin Poliana Palma Rigo Thiesen, Mariana Macedo Ribas, Guilherme Schmitt de Andrade, Flávia Pardo Salata Nahsan, Vera Lúcia Schmitt, Fabiana Scarparo Naufel
Quanto menor a superficie da area, maior a resistencia de uniao, pois, especimes com pequena area de superficie apresentam melhor distribuicao de estresse, bem como reduzido numero de defeitos internos. O objetivo deste estudo foi verificar a resistencia de uniao ao microcisalhamento de especimes com dois diferentes diâmetros, 0.55 mm e 0.76 mm. 40 fatias de cerâmica Suprinity, com 1,3 mm de espessura, polidas em lixa #600, foram divididas aleatoriamente em dois grupos (n=20). Em cada fatia, quatro areas adesivas foram delimitadas por fita adesiva, sendo entao fixadas as matrizes circulares. Os especimes foram condicionados com acido fluoridrico a 5% (FGM) por 20 s, lavados e secos; entao silanizados (RelyX Ceramic Primer - 3M ESPE) e secos com jato de ar. As matrizes foram preenchidas com cimento resinoso RelyX U200 3M ESPE e fotopolimerizadas por 100 s. Apos 24 h em agua deionizada a 37o C, os especimes foram submetidos ao teste de microcisalhamento sob velocidade de 0,5 mm/min. Os dados normais e homogeneos foram submetidos a ANOVA para o experimento inteiramente casualizado, nao exibindo diferenca significativa (p =0,62) entre as duas areas avaliadas – 23,74±4,49 e 24,85±4,41, respectivamente para as areas 0,55 e 0,76 mm. Concluimos que, nao ha diferenca na resistencia de uniao ao microcisalhamento quando se utilizam as diferentes areas adesivas estudadas.
表面面积越小,粘结强度越高,因为表面面积小的标本表现出更好的应力分布,减少了内部缺陷的数量。本研究的目的是验证0.55 mm和0.76 mm两种不同直径的样品的微剪切粘结强度。40片1.3 mm厚的供应陶瓷片,用600号砂纸抛光,随机分为两组(n=20)。在每个切片中,用胶带划分四个粘接区域,然后固定圆形矩阵。用5%氟酸(FGM)蚀刻20 s,清洗干燥;然后硅烷化(RelyX陶瓷底漆- 3M ESPE),用空气喷射干燥,用RelyX U200 3M ESPE树脂水泥填充基体,光固化100 s。在37℃去离子水中浸泡24小时后,在0.5 mm/min的速度下进行微剪切试验。在完全随机试验中,正态和均质数据进行方差分析,两个评估区域之间的差异无显著性(p = 0.62),分别为0.55和0.76 mm区域的23.74±4.49和24.85±4.41。我们的结论是,当使用不同的粘结区域时,微剪切粘结强度没有差异。
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引用次数: 0
INFLUENCE OF POST-BLEACHING TIME INTERVALS USING 37% CARBAMIDE PEROXIDE ON DENTAL SUBSTRATE ADHESION 37%过氧化脲漂白后时间间隔对牙基质粘附的影响
Pub Date : 2017-12-05 DOI: 10.17765/1518-1243.2017V19N2P187-194
S. Yamakami, J. Faraoni, Daniela Pires Caslini, M. Chinelatti, R. Palma-Dibb
The aim of this study was to evaluate the influence of post-bleaching time intervals using 37% carbamide peroxide on dental substrate adhesion. Fifty bovine incisors were sectioned in two groups of 4X4 mm standard blocks to obtain 50 specimens in each group (n=50). In fifty blocks, the dentin (D) was analyzed and in the other 50 the enamel (E). Blocks were subjected to bleaching treatment and restored with Single Bond/z250 according to post-bleaching time intervals (0, 7, 14 and 21 days). Twenty-four hours after adhesive/resin cylinders on substrate confection, shear bond strength test (SBS) was performed in an universal test machine. Means in MPa and their respective standard deviations were: E – control: 31.89 (2.39); T0: 19.07 (2.00); T7: 24.97 (4.89); T14: 29.71 (4.89); T21: 40.91 (4.75) and D – control: 18.90 (3.64); T0: 2.22 (0.41); T7: 3.79 (0.75); T14: 5.95 (0.79); T21: 8.40 (0.87). Data were submitted to ANOVA and Tukey (p< 0.05) tests. The bond strength value for the enamel was statistically higher than the dentin, and both were lower than the control group that had similar results after 21 days post-bleaching. In dentin group, the control showed superior bond strength and was statistically different in relation to other times. It was concluded that bleaching had negative influence on adhesion. Therefore it is necessary to wait, at least, 21 days after bleaching to restore the enamel. AVALIACAO IN VITRO DA INFLUENCIA DE DIFERENTES INTERVALOS DE TEMPO POS-CLAREAMENTO COM PEROXIDO DE CARBAMIDA 37% NA ADESAO AO SUBSTRATO DENTAL RESUMO: O objetivo deste estudo foi avaliar a influencia do peroxido de carbamida a 37% sobre a adesao dos substratos dentarios em diferentes intervalos de tempo pos-clareamento. Cinquenta incisivos bovinos foram divididos em dois grupos de blocos padrao 4 x 4 mm para obter 50 especimes de cada grupo (n = 50). Em cinquenta blocos, a dentina (D) foi analisada e nos outros 50 o esmalte (E). Os blocos foram submetidos ao tratamento de clareamento e restaurados com Single Bond/z250 de acordo com os intervalos de tempo pos-clareamento (0, 7, 14 e 21 dias). Apos vinte e quatro horas os corpos de prova preparados com adesivo/resina foram submetidos ao teste de resistencia ao cisalhamento (SBS) em uma maquina universal de ensaio. As medias (Mpa) e seus respectivos desvios padrao foram: E - controle: 31,89 (2,39); T0: 19,07 (2,00); T7: 24,97 (4,89); T14: 29,71 (4,89); T21: 40,91 (4,75) e D - controle: 18,90 (3,64); T0: 2,22 (0,41); T7: 3,79 (0,75); T14: 5,95 (0,79); T21: 8,40 (0,87). Os dados foram submetidos a ANOVA e ao teste de Turkey (p <0,05). O valor da resistencia de uniao para o esmalte foi estatisticamente superior a dentina e ambos foram inferiores ao grupo controle que apresentou resultados semelhantes apos 21 dias pos-branqueamento. O grupo controle (D) apresentou valores de resistencia de uniao superior e estatisticamente diferente em relacao aos outros tempos. Concluiu-se que o clareamento teve influencia
本研究的目的是评估使用37%过氧化脲漂白后时间间隔对牙基质粘附的影响。50只牛切牙分两组4X4 mm标准块切片,每组50只(n=50)。在50个牙块中,对牙本质(D)进行分析,对另外50个牙釉质(E)进行分析。牙块进行漂白处理,并根据漂白后的时间间隔(0、7、14和21天)使用Single Bond/z250进行修复。胶粘剂/树脂圆柱体在基材上配制24小时后,在通用试验机上进行剪切粘结强度试验(SBS)。MPa均值及标准差分别为:E - control: 31.89 (2.39);成绩:19.07 (2.00);T7: 24.97 (4.89);T14: 29.71 (4.89);T21: 40.91 (4.75), D - control: 18.90 (3.64);T0: 2.22 (0.41);T7: 3.79 (0.75);T14: 5.95 (0.79);T21: 8.40(0.87)。数据采用ANOVA和Tukey检验(p< 0.05)。牙釉质与牙本质的结合强度值有统计学意义上高于牙本质,但在漂白21天后,两者均低于结果相似的对照组。在牙本质组中,对照组表现出更强的粘结强度,且与其他时间相比有统计学差异。结果表明,漂白对附着力有不利影响。因此,漂白后至少需要等待21天才能恢复牙釉质。目的:研究不同时间间隔的体外数据影响、不同时间间隔的体外数据影响、不同时间间隔的体外数据影响、不同时间间隔的体外数据影响、不同时间间隔的体外数据影响、不同时间间隔的体外数据影响。牛有孔虫组为5 × 4 mm,对照组为50例(n = 50)。Em cinquenta blocos, a dentina (D), a dentina (e), a dentina (D), a dentina (e), a dentina (D), a dentina (e)。o blocos foram submetidos of treatment of clemenment, e restaurados com Single Bond/z250 de acordo com Os intervalos de tempo - clemenment(0,7,14 - 21)。本研究的目的是研究复合材料的制备方法、粘合剂/树脂复合材料的制备方法、抗化学腐蚀(SBS)的方法和应用。作为媒介(Mpa),我们有各自的研究方向:e - control: 31,89 (2,39);[00:19,07] (2000);T7: 24,97 (4,89);T14: 29,71 (4,89);T21: 40,91 (4,75) e D -控制:18,90 (3,64);T0: 2,22 (0,41);T7: 3,79 (0,75);T14: 5,95 (0,79);T21: 8,40(0,87)。在土耳其,两组间的差异有统计学意义(p < 0.05)。研究结果表明,采用统计学方法改良的上颌牙体、上颌牙体、下颌牙体和对照组的抗牙周炎患者的抗牙周炎能力均优于对照组。对照组(D组)的抗药能力明显优于对照组(p < 0.05),与对照组的抗药能力有统计学差异。结论:采用明确的方法对患者的负面影响进行治疗。Portanto, tornar-s -a necessary guarardar, pelo menos, 21个diapos,用于澄清餐厅或小型餐厅。PALAVRAS-CHAVE: Clareadores;Peroxidos;Dentina;Esmalte Dentario。
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引用次数: 0
AUTOPERCEPÇÃO DAS CONDIÇÕES DE SAÚDE BUCAL EM ADULTOS DO SUL DO BRASIL 巴西南部成人口腔健康状况的自我认知
Pub Date : 2017-12-05 DOI: 10.17765/1518-1243.2017v19n2p119-125
Roberta Vedana Erckmann, Mirian Kuhnen, Everley Rosane Goetz, A. Masiero
Oral health is still an important issue in public health. Population-based studies are relevant to identify priority groups and the investigation of people´s self-perception within the context complement objective analysis, with other meanings for planned health activities. Self-perception of oral health and associated factors in adults of a Basic Health Unit coupled to Family Health Strategy in south Brazil are investigated. Further, 207 subjects participated and data were collected by a subjective interview (Oral Health Impact Profile questionnaire – a concise version and clinical exam). Results identified that 43.0% of the population under analysis evaluated their mouth health as positive. There was an association between age (p=0.036), color (p=0.030) and schooling (p=0.022), with positive self-perception. When asked about the need for treatment, 71.5% answered that they required dental intervention. Most failed to perceive the relationship when questioned on the impact of mouth conditions on their life quality. Clinical examination revealed that 48.2% had teeth caries and 81.7% required prosthesis. Health education should be underscored so that the population perceives the relationship between mouth health and general health and life quality.
口腔健康仍然是公共卫生中的一个重要问题。以人口为基础的研究与确定优先群体有关,在背景下对人们自我认知的调查补充了客观分析,对有计划的卫生活动具有其他意义。在巴西南部的一个基本卫生单位与家庭卫生战略相结合的成年人的口腔健康自我认知和相关因素进行了调查。此外,207名受试者参与并通过主观访谈(口腔健康影响概况问卷-简明版本和临床检查)收集数据。结果表明,43.0%的被分析人群对口腔健康的评价为阳性。年龄(p=0.036)、肤色(p=0.030)和学校教育(p=0.022)与积极的自我知觉存在相关性。当被问及是否需要治疗时,71.5%的人回答需要牙科干预。当被问及口腔状况对生活质量的影响时,大多数人都没有意识到这种关系。临床检查显示48.2%的患者有龋齿,81.7%的患者需要种植义齿。应强调健康教育,使人们认识到口腔健康与一般健康和生活质量之间的关系。
{"title":"AUTOPERCEPÇÃO DAS CONDIÇÕES DE SAÚDE BUCAL EM ADULTOS DO SUL DO BRASIL","authors":"Roberta Vedana Erckmann, Mirian Kuhnen, Everley Rosane Goetz, A. Masiero","doi":"10.17765/1518-1243.2017v19n2p119-125","DOIUrl":"https://doi.org/10.17765/1518-1243.2017v19n2p119-125","url":null,"abstract":"Oral health is still an important issue in public health. Population-based studies are relevant to identify priority groups and the investigation of people´s self-perception within the context complement objective analysis, with other meanings for planned health activities. Self-perception of oral health and associated factors in adults of a Basic Health Unit coupled to Family Health Strategy in south Brazil are investigated. Further, 207 subjects participated and data were collected by a subjective interview (Oral Health Impact Profile questionnaire – a concise version and clinical exam). Results identified that 43.0% of the population under analysis evaluated their mouth health as positive. There was an association between age (p=0.036), color (p=0.030) and schooling (p=0.022), with positive self-perception. When asked about the need for treatment, 71.5% answered that they required dental intervention. Most failed to perceive the relationship when questioned on the impact of mouth conditions on their life quality. Clinical examination revealed that 48.2% had teeth caries and 81.7% required prosthesis. Health education should be underscored so that the population perceives the relationship between mouth health and general health and life quality.","PeriodicalId":30388,"journal":{"name":"Iniciacao Cientifica Cesumar","volume":"19 1","pages":"119-125"},"PeriodicalIF":0.0,"publicationDate":"2017-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67826992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A importância da calibragem para avaliação radiográfica de anomalias dentárias de pacientes com câncer 校准对癌症患者牙齿异常影像学评估的重要性
Pub Date : 2017-12-05 DOI: 10.17765/1518-1243.2017V19N2P171-177
A. Rodrigues, R. A. Quispe, Ana Lúcia Alvares Capelozza, Cassia Maria Fischer Rubira, Ana Maria Greff Buaes, P. S. Santos
Anomaly is a variation or deviation of an anatomic characteristic or structure from normality. Due to anti-cancer treatments, survival children with cancer are prone to have dental anomalies as a delayed effect revealed by full-mouth radiography. However, examiners should have previous training, assessed by concordance tests (Kappa test) for reliable and reproducible results. Calibration is important for examiners to evaluate dental anomalies in patients with cancer so that highly reliable data may be obtained. Forty full-mouth radiographies, twenty of control group and 20 of the experimental group, were randomly selected. Examiners proved to be calibrated when Kappa test rates were between 0.61and 1.0. Intra-examiner calibration featured between least (0.61-0.80) and maximum concordance (0.81 – 1.0) for the two examiners. In the case of inter-examiner calibration, minimum Kappa featured moderate concordance (0.41 – 0.60) during the first stage; whilst a substantial concordance was reached (0.61-0.80) in the second stage, proving standardization of examiners. A careful and detailed calibration is required to evaluate dental anomalies in full-mouth radiographies, enhancing reliable and reproducible information for scientific evidence.
异常是解剖特征或结构与正常的变异或偏差。由于抗癌治疗,幸存的癌症儿童很容易出现牙齿异常,这是全口x线摄影显示的延迟效应。然而,审查员应该有先前的培训,通过一致性测试(卡帕测试)评估可靠和可重复的结果。校准对于检查人员评估癌症患者的牙齿异常非常重要,因此可以获得高度可靠的数据。随机抽取全口x线片40张,对照组20张,试验组20张。当Kappa测试率介于0.61至1.0之间时,审查员被证明是校准的。两名审查员的内部校准一致性在最小(0.61-0.80)和最大(0.81 - 1.0)之间。在审查员间校准的情况下,最小Kappa在第一阶段具有中等一致性(0.41 - 0.60);而在第二阶段达到了实质性的一致性(0.61-0.80),证明了审查员的标准化。需要仔细和详细的校准来评估全口x光片中的牙齿异常,以增强科学证据的可靠性和可重复性信息。
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引用次数: 0
MOTIVAÇÃO DE HIGIENE BUCAL POR MEIO DE ATIVIDADES LÚDICAS 通过娱乐活动激励口腔卫生
Pub Date : 2017-12-05 DOI: 10.17765/1518-1243.2017v19n2p111-117
Silvana Marchiori de Araújo, Maria Eugênia Schulz, Cintia Regina de Sena, E. Silveira
O objetivo deste estudo foi verificar a eficacia de intervencoes ludicas na motivacao da higiene bucal em criancas de sete a oito anos de idade, de uma escola publica do municipio de Itajai/SC. Participaram do estudo 14 criancas, que foram aleatoriamente divididas em dois grupos; um grupo teve orientacao de higiene e o outro grupo com orientacao de higiene conjunto a motivacao por meio de atividades ludicas. A afericao da condicao de higiene bucal foi por meio do Indice de Higiene Oral - Simplificado (IHO-S), realizado em todas as criancas no primeiro encontro antes de qualquer orientacao, e novamente em intervalos de sete, 14, 21 dias. Resultados mostraram que houve melhora na media do indice de placa no grupo experimental de 0,16, e piora no grupo controle de 0,27. Alem disso, foi verificada diferenca estatistica significativa dos indices medios do IHO-S do grupo experimental quando comparado ao grupo controle. Foi concluido que as atividades ludicas foram eficazes no indice de placa bacteriana no grupo estudado
本研究的目的是验证游戏干预对Itajai/SC市一所公立学校7至8岁儿童口腔卫生动机的有效性。14名儿童被随机分为两组;一组以卫生为导向,另一组以卫生为导向,以娱乐活动为动机。采用简化口腔卫生指数(IHO- s)对所有儿童进行口腔卫生状况评估,并在任何咨询前的第一次会议上进行评估,每隔7、14、21天再次进行评估。结果表明,实验组钢板指数平均改善0.16,对照组钢板指数平均恶化0.27。此外,与对照组相比,实验组的平均IHO-S指数有显著差异。结果表明,游戏活动对研究组的菌斑指数有效
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引用次数: 0
ANÁLISE DO PADRÃO DE FRATURAS EM PINOS ANATOMIZADOS CIMENTADOS COM DIFERENTES AGENTES CIMENTANTES 不同胶凝剂胶结解剖桩的骨折模式分析
Pub Date : 2017-12-05 DOI: 10.17765/1518-1243.2017V19N2P145-151
Raísa Cristina Madeira Barbosa, N. Souza, A. Pereira, V. Rodrigues, I. Santana
The breaking pattern in teeth with glass fiber pins (GFP), anatomized and fixed with different cementing agents, is analyzed in vitro. Thirty bovine mandibular uni-radicular teeth were used. Roots were treated endodontically and randomly divided into two groups according to the cementing agent employed, or rather, G1: auto-adhesive resinous cement (RelyX U200-3M ESPE), and G2: conventional resinous cement (Allcem-FGM). After the anatomization and cementation of pins, the specimens were stored in a buffer at 37oC for 7 days. Roots were then cut under flowing water and six 1mm-thick slices were cut, totaling 180 specimens. The push-out test was performed for all specimens and then placed under a light microscope to assess the type of fracture. The most frequent type of fracture for the two groups comprised coesine in dentin (G1 = 32.2%; G2 = 30%). There was a statistically greater frequency in adhesive failures between dentin and cement in G2 (p=0.007), with a statistically higher frequency (p=0.027) of cohesive fracture in dentin in the third cervical (38.3%) when compared to the third apical (20.0%). Results suggest that auto-adhesive cement (RelyX U200-3M ESPE) had more positive results in the analysis of fracture patterns.
对玻璃纤维销(GFP)牙体解剖和不同固接剂固定后的断裂模式进行了体外分析。选用30颗牛下颌骨单根牙。对牙根进行根管治疗,根据使用的胶结剂随机分为两组,G1:自粘树脂水泥(RelyX U200-3M ESPE), G2:常规树脂水泥(allem - fgm)。解剖钉固接后,标本在37℃的缓冲液中保存7天。然后在流水下切开根,切下6片1mm厚的薄片,共180个标本。对所有标本进行推出试验,然后置于光镜下评估骨折类型。两组最常见的骨折类型为牙本质内骨折(G1 = 32.2%;G2 = 30%)。G2组牙本质与骨水泥粘连失败的发生率有统计学意义(p=0.007),其中第三颈椎牙本质粘连骨折发生率(38.3%)高于第三根尖牙本质粘连骨折发生率(20.0%)(p=0.027)。结果表明,自动粘接水泥(RelyX U200-3M ESPE)在分析骨折模式方面具有更积极的效果。
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引用次数: 0
INIBIDORES DA GSK-3: UMA NOVA ESTRATÉGIA PARA A REGENERAÇÃO DENTAL GSK-3抑制剂:牙科再生的新策略
Pub Date : 2017-12-05 DOI: 10.17765/1518-1243.2017V19N2P195-204
Caroline Orejana Ghizzi Bentos, Airton Vicente Pereira
The enzyme glycogen synthase kinase 3 (GSK-3) regulates several stages in cell biochemistry and the alterations in its activity involve many diseases. Since the 1990s, GSK-3 became a target site for the development of new drugs and several inhibitors were evaluated for the treatment of pathologies, such as diabetes and Alzheimer disease. Tideglusib is a GSK-3 inhibitor for the treatment of Alzheimer disease. It has been recently demonstrated that the drug may induce the natural repair of the dental pulp through the activation of stamina cells by regenerating dental material of the damaged area. The natural regeneration process is an innovation among dental restoration techniques since it stimulates the multiplication of dental pulp cells and blocks small cavities. The role of GSK-3, its inhibitors and the effects of tideglusib in dental regeneration are investigated.
糖原合成酶激酶3 (GSK-3)调节着细胞生化的多个阶段,其活性的改变涉及多种疾病。自20世纪90年代以来,GSK-3成为新药开发的靶点,几种抑制剂被评估用于治疗糖尿病和阿尔茨海默病等疾病。Tideglusib是一种用于治疗阿尔茨海默病的GSK-3抑制剂。最近有研究表明,该药可以通过再生受损部位的牙材料,激活耐力细胞,从而诱导牙髓的自然修复。自然再生是牙体修复技术中的一项创新,因为它可以刺激牙髓细胞的增殖并阻断小腔。本文研究了GSK-3及其抑制剂在牙再生中的作用和tideglusib在牙再生中的作用。
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引用次数: 0
ALTERAÇÃO DA MICRODUREZA SUPERFICIAL DO ESMALTE DENTÁRIO EXPOSTOS A CHÁS INDUSTRIALIZADOS 工业化茶暴露牙釉质表面显微硬度的变化
Pub Date : 2017-12-05 DOI: 10.17765/1518-1243.2017V19N2P135-143
Nayanna Lana Soares Fernandes, Ingrid Andrade Meira, J. Lavôr, Andressa Bezerra de Oliveira, F. C. Sampaio
The erosion capacity of industrialized teas on the dental enamel is evaluated according to the percentage of dental surface hardness loss (%DHL), pH, acid titration and buffer capacity. Six types of industrialized teas, featuring different brands and tastes, were analyzed. Mineral water-Crystal® and Coca-Cola® were respectively the negative and positive controls. Measurements of pH and titration were prepared in triplicate, in a 50ml beverage. Buffer capacity was calculated on pH rates and acid titration for pH 7.0. Micro-hardness of enamel surface was evaluated prior to and after the erosive test. ANOVA and Pearson´s correlation tests at p<0.05 were employed to analyze data which, in turn, provided normal distribution. There was significant difference between the teas and controls in all variables (ANOVA, p<0.05). The pH of teas ranged between 2.25 (Black tea with lemon) and 3.39 (Matte with lemon). Highest rates for acid titration (2.05) and buffer capacity (8.30) occurred in Black tea with lemon. Highest %DHL rate occurred in Peach tea, whilst the lowest in Natural Matte tea. There was a statistically significant difference in %DHL for all teas when compared to negative control and %PMD of all types of tea was higher than that of positive control. There were significant co-relationships (p<0.05) between initial pH initial with acid titration and buffer capacity, and between %PMD and initial pH, acid titration and buffer capacity. Results showed that all teas had an erosive trait on the dental enamel, with intensity variation according to taste and composition.
根据牙表面硬度损失百分比(%DHL)、pH值、酸滴定和缓冲能力来评价工业化茶叶对牙釉质的侵蚀能力。对六种不同品牌和口味的工业化茶叶进行了分析。矿泉水-水晶®和可口可乐®分别为阴性对照和阳性对照。在50ml的饮料中测量pH值和滴定,一式三份。根据pH值和pH 7.0的酸滴定计算缓冲容量。在腐蚀试验前后对牙釉质表面进行显微硬度评价。采用方差分析(ANOVA)和Pearson相关检验(p<0.05)对数据进行分析,结果为正态分布。茶组与对照组在各变量上差异均有统计学意义(方差分析,p<0.05)。茶的pH值在2.25(柠檬红茶)和3.39(柠檬哑光茶)之间。柠檬红茶的酸滴定率最高(2.05),缓冲能力最高(8.30)。桃茶的DHL率最高,而天然哑光茶的DHL率最低。与阴性对照相比,所有茶的百分比DHL都有统计学上的显著差异,所有茶的百分比PMD都高于阳性对照。初始酸滴定pH值与缓冲容量、%PMD值与初始pH值、酸滴定值和缓冲容量呈显著相关(p<0.05)。结果表明,所有茶叶对牙釉质均有侵蚀作用,且侵蚀程度随口味和成分的不同而不同。
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引用次数: 0
SAÚDE BUCAL E QUALIDADE DE VIDA NO PACIENTE PÓS-RADIOTERAPIA DE CÂNCER DE CABEÇA E PESCOÇO 头颈部癌症放疗后患者的口腔健康和生活质量
Pub Date : 2017-12-05 DOI: 10.17765/1518-1243.2017V19N2P163-169
L. C. Oliveira, D. F. Teixeira, Cassia Maria Fischer Rubira, P. S. Santos
Radiotherapy in a patient with head and neck cancer may produce several negative consequences, such as hypo-salivation. Due to lack of protection by saliva, increase in the number of caries and other periodontal diseases is a risky problem which may cause teeth loss and may impact life quality through mouth health. The impact of mouth health on life quality of post-radiotherapy patients with head and neck cancer is evaluated by evaluating saliva flow and toothlessness. Sample comprised 19 individuals, over 18 years, diagnosed with head and neck cancer. Modulated Intensity Radiotherapy featured in 16 (68.4%) patients, of whom nine (47.4%) ended treatment one year before. Fifteen patients (79.9%) experienced mouth health impacting their life quality. Seven patients (36.8%) did not wear any prosthesis and nine (47.4%) required a combination of rehabilitations. Fifteen (78.9%) patients had low saliva flow and four (21.1%) had better saliva flow after five years of radiotherapy. Pearson´s Coefficient of Co-relation revealed co-relationship between the need for prosthesis and age (p=0.006; r=0.4734) and the need of prosthesis and saliva flow (p=0.03; r=0.3672). Radiotherapy complications on head and neck bring several physical and psychological issues. In some cases, the post-radiotherapy period improves saliva flow, but there is no impact of mouth therapy on life quality in a less-than-one-year treatment. Longitudinal studies with such populations are required to investigate deeply the effect of radiotherapy throughout the years.
头部和颈部癌症患者的放射治疗可能会产生一些负面后果,如低生存率。由于缺乏唾液的保护,龋齿和其他牙周疾病的数量增加是一个危险的问题,可能会导致牙齿脱落,并可能通过口腔健康影响生活质量。通过评估唾液流量和牙齿缺失,评估口腔健康对癌症头颈部放疗后患者生活质量的影响。样本包括19名年龄超过18岁的患者,他们被诊断患有癌症。16名(68.4%)患者接受了调强放射治疗,其中9名(47.4%)患者在一年前结束了治疗。15名患者(79.9%)的口腔健康影响了他们的生活质量。7名患者(36.8%)没有佩戴任何假体,9名患者(47.4%)需要联合康复。15名(78.9%)患者在放疗五年后唾液流量较低,4名(21.1%)患者唾液流量较好。Pearson相关系数揭示了假体需求与年龄(p=0.006;r=0.4734)、假体需求与唾液流量(p=0.03;r=0.3672)之间的相关性。头颈部放射治疗并发症带来了一些生理和心理问题。在某些情况下,放疗后可以改善唾液流量,但在不到一年的治疗中,口腔治疗对生活质量没有影响。需要对这些人群进行纵向研究,以深入研究多年来放射治疗的效果。
{"title":"SAÚDE BUCAL E QUALIDADE DE VIDA NO PACIENTE PÓS-RADIOTERAPIA DE CÂNCER DE CABEÇA E PESCOÇO","authors":"L. C. Oliveira, D. F. Teixeira, Cassia Maria Fischer Rubira, P. S. Santos","doi":"10.17765/1518-1243.2017V19N2P163-169","DOIUrl":"https://doi.org/10.17765/1518-1243.2017V19N2P163-169","url":null,"abstract":"Radiotherapy in a patient with head and neck cancer may produce several negative consequences, such as hypo-salivation. Due to lack of protection by saliva, increase in the number of caries and other periodontal diseases is a risky problem which may cause teeth loss and may impact life quality through mouth health. The impact of mouth health on life quality of post-radiotherapy patients with head and neck cancer is evaluated by evaluating saliva flow and toothlessness. Sample comprised 19 individuals, over 18 years, diagnosed with head and neck cancer. Modulated Intensity Radiotherapy featured in 16 (68.4%) patients, of whom nine (47.4%) ended treatment one year before. Fifteen patients (79.9%) experienced mouth health impacting their life quality. Seven patients (36.8%) did not wear any prosthesis and nine (47.4%) required a combination of rehabilitations. Fifteen (78.9%) patients had low saliva flow and four (21.1%) had better saliva flow after five years of radiotherapy. Pearson´s Coefficient of Co-relation revealed co-relationship between the need for prosthesis and age (p=0.006; r=0.4734) and the need of prosthesis and saliva flow (p=0.03; r=0.3672). Radiotherapy complications on head and neck bring several physical and psychological issues. In some cases, the post-radiotherapy period improves saliva flow, but there is no impact of mouth therapy on life quality in a less-than-one-year treatment. Longitudinal studies with such populations are required to investigate deeply the effect of radiotherapy throughout the years.","PeriodicalId":30388,"journal":{"name":"Iniciacao Cientifica Cesumar","volume":"19 1","pages":"163-169"},"PeriodicalIF":0.0,"publicationDate":"2017-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48656922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Iniciacao Cientifica Cesumar
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