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Prescribed burn related increases of population exposure to PM2.5 and O3 pollution in the southeastern US over 2013–2020 2013-2020 年间美国东南部地区与烧荒相关的 PM2.5 和 O3 污染人口暴露增加情况
IF 10.3 1区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-01 DOI: 10.1016/j.envint.2024.109101
Kamal J. Maji , Zongrun Li , Yongtao Hu , Ambarish Vaidyanathan , Jennifer D. Stowell , Chad Milando , Gregory Wellenius , Patrick L. Kinney , Armistead G. Russell , M. Talat Odman
Ambient air quality across the southeastern US has improved substantially in recent decades. However, emissions from prescribed burns remain high, which may pose a substantial health threat. We employed a multistage modeling framework to estimate year-round, long-term effects of prescribed burns on air quality and premature deaths. The framework integrates a chemical transport model with a data-fusion approach to estimate 24-h average PM2.5 and maximum daily 8-h averaged O3 (MDA8-O3) concentrations attributable to prescribed burns for the period 2013–2020. The Global Exposure Mortality Model and a log-linear exposure–response function were used to estimate the premature deaths ascribed to long-term prescribed burn PM2.5 and MDA8-O3 exposure in ten southeastern states. Our results indicate that prescribed burns contributed on annual average 0.59 ± 0.20 µg/m3 of PM2.5 (∼10 % of ambient PM2.5) over the ten southeastern states during the study period. On average around 15 % of the state-level ambient PM2.5 concentrations were contributed by prescribed burns in Alabama (0.90 ± 0.15 µg/m3), Florida (0.65 ± 0.19 µg/m3), Georgia (0.91 ± 0.19 µg/m3), Mississippi (0.65 ± 0.10 µg/m3) and South Carolina (0.65 ± 0.09 µg/m3). In the extensive burning season (January–April), daily average contributions to ambient PM2.5 increased up to 22 % in those states. A large part of Alabama and Georgia experiences ≥3.5 µg/m3 prescribed burn PM2.5 over 30 days/year. Additionally, prescribed burns are responsible for an average increase of 0.32 ± 0.12 ppb of MDA8-O3 (0.8 % of ambient MDA8-O3) over the ten southeastern states. The combined effect of prescribed burn PM2.5 exposure, population growth, and increase of baseline mortality over time resulted in a total of 20,416 (95 % confidence interval (CI): 16,562–24,174) excess non-accidental premature deaths in the ten southeastern states, with 25 % of these deaths in Georgia. Prescribed burn MDA8-O3 was responsible for an additional 1,332 (95 % CI: 858–1,803) premature deaths in the ten southeastern states. These findings indicate significant impacts from prescribed burns, suggesting potential benefits of enhanced forest management strategies.
近几十年来,美国东南部的环境空气质量有了很大改善。然而,规定焚烧的排放量仍然很高,这可能会对健康造成严重威胁。我们采用了一个多阶段建模框架来估算全年、长期的规定焚烧对空气质量和过早死亡的影响。该框架将化学传输模型与数据融合方法相结合,以估算 2013-2020 年期间可归因于规定燃烧的 24 小时平均 PM2.5 和最大日 8 小时平均臭氧(MDA8-O3)浓度。我们使用全球暴露死亡率模型和对数线性暴露-响应函数来估算东南部十个州因长期暴露于规定燃烧的 PM2.5 和 MDA8-O3 而导致的过早死亡人数。研究结果表明,在研究期间,东南部十个州的PM2.5年均浓度为0.59 ± 0.20 µg/m3(占环境PM2.5的10%)。阿拉巴马州(0.90 ± 0.15 µg/m3)、佛罗里达州(0.65 ± 0.19 µg/m3)、佐治亚州(0.91 ± 0.19 µg/m3)、密西西比州(0.65 ± 0.10 µg/m3)和南卡罗来纳州(0.65 ± 0.09 µg/m3)的州级环境 PM2.5 浓度平均约有 15% 来自于规定燃烧。在大面积燃烧的季节(1 月至 4 月),这些州的环境 PM2.5 日均浓度最高增加了 22%。阿拉巴马州和佐治亚州的大部分地区每年有 30 天的规定焚烧 PM2.5 ≥3.5 µg/m3。此外,在东南部十个州中,规定燃烧导致 MDA8-O3 平均增加了 0.32 ± 0.12 ppb(占环境 MDA8-O3 的 0.8%)。随着时间的推移,PM2.5 暴露、人口增长和基线死亡率增加的综合效应导致东南部十个州总共有 20,416 人(95% 置信区间 (CI):16,562-24,174)非意外过早死亡,其中 25% 的死亡发生在佐治亚州。在东南部的十个州中,MDA8-O3 规定燃烧造成了额外的 1,332 例过早死亡(95 % CI:858-1,803 例)。这些研究结果表明,规定燃烧会产生重大影响,这表明加强森林管理策略具有潜在的益处。
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引用次数: 0
Environmental endocrine disrupting chemical-DEHP exposure-provoked biotoxicity about microbiota-gut-mammary axis in lactating mice via multi-omics technologies 通过多组学技术研究环境内分泌干扰化学物质--DEHP暴露引起的哺乳小鼠微生物群-肠道-乳腺轴的生物毒性
IF 10.3 1区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-01 DOI: 10.1016/j.envint.2024.109130
Xiaolong Xu, Yonglong He, Zefang Cheng, Haoyuan Zhang, Yijian Chu, Zhewei Wang, Xiaopeng An
Plastics, pervasive in humans and nature, often contain Di (2-ethylhexyl) phthalate (DEHP) that enhance plastic’s elasticity. However, DEHP is an environmental endocrine disruptor, affecting organisms upon exposure. Understanding mammary gland development in lactating females is crucial for offspring nourishment and dairy production. Employing multi-omics technology, this study aimed to uncover DEHP’s impact on the microbial–gut–mammary axis. Forty mice were exposed to varying DEHP doses for 18 d. We performed 16S sequencing, metabolomics, mammary tissue observation, and gene expression profiling. Results revealed DEHP’s influence on microbial diversity, with increased Lactobacillus abundance and reduced Proteobacteria, alongside colonic inflammation. Elevated GMP and adenosine 5′-monophosphate levels in the bloodstream were noted, while ascorbic acid, glycitein, and others decreased. MEHP, a DEHP metabolite, damaged mammary tissues, inhibiting ERK1/2 phosphorylation, triggering apoptosis and ferroptosis. These findings unveil potential therapeutic targets for DEHP-induced chronic toxicity in humans and animals, aiding dairy livestock health and human well-being. This study underscores the importance of understanding the adverse effects of DEHP exposure on mammalian systems.
塑料在人类和自然界中普遍存在,通常含有邻苯二甲酸二(2-乙基己酯)(DEHP),可增强塑料的弹性。然而,DEHP 是一种环境内分泌干扰物,生物一旦接触就会受到影响。了解哺乳期雌性动物乳腺的发育对后代的营养和乳制品生产至关重要。本研究采用多组学技术,旨在揭示DEHP对微生物-肠道-乳腺轴的影响。我们进行了 16S 测序、代谢组学、乳腺组织观察和基因表达谱分析。结果表明,DEHP 会影响微生物多样性,增加乳酸杆菌的数量,减少变形杆菌,同时引发结肠炎症。血液中的 GMP 和腺苷-5′-单磷酸水平升高,而抗坏血酸、甘氨酸和其他物质则下降。DEHP的代谢物MEHP会破坏乳腺组织,抑制ERK1/2磷酸化,引发细胞凋亡和铁变态反应。这些发现揭示了DEHP诱导的人类和动物慢性毒性的潜在治疗靶点,有助于奶畜健康和人类福祉。这项研究强调了了解 DEHP 暴露对哺乳动物系统不良影响的重要性。
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引用次数: 0
Strategic carbon emission assessment in sludge treatment: A dynamic tool for low-carbon transformation 污泥处理中的战略性碳排放评估:低碳转型的动态工具
IF 10.3 1区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-01 DOI: 10.1016/j.envint.2024.109124
Xin-Lei Yu , Jie Ding , Shan-Shan Yang , Ji-Wei Pang , Mei-Yun Lu , Xian Zhao , Shan-Shan He , Lu-Yan Zhang , Nan-Qi Ren
The carbon–neutral target presents a significant challenge for the sewage sludge treatment and disposal (SSTD) industry, necessitating strategic planning for a low-carbon transition. However, flexible and comprehensive carbon emission analysis tools to support this goal remain lacking. This study presents a carbon emission analysis tool to evaluate the carbon emission characteristics and future mitigation potentials of SSTD. The tool integrates life cycle inventory (LCI) modeling-based analysis, sensitivity analysis, regression analysis, and scenario analysis. Carbon emissions are dynamically calculated based on sludge properties, technological level, and industry external parameters, providing a foundation for adaptable evaluation tailored to local conditions. The framework considers the potential effects of multi-parameter and multi-aspect changes in scene design, both within and outside the industry, to achieve dynamic and comprehensive simulations. A case study conducted in Wuhan, China, demonstrated the usability and application processes of the framework. The results indicated that carbon emissions from SSTD are projected to more than double from 2021 to 2060 without interventions. Among the mitigation measures, energy and chemical savings would yield the largest reduction potential, followed by the technical layout adjustment and the promotion of energy efficiency. Operational optimization in the sludge industry and outside the industry would contribute the least. With all mitigation measures applied, emissions could decrease to –82.91 kt CO2-eq in 2060, equivalent to 13.03% compensation for emissions from the sewage treatment line. Among all the processes, incineration routes are recommended due to their current and future low carbon emissions. The cooperative resource route of anaerobic digestion and land use also shows promise as it progressively demonstrates superior performance with increasing organic matter and nutrient content of sludge. Critical factors, sub-processes, and emission types for different routes were identified and can be optimized accordingly. The developed method demonstrates sufficient flexibility to be applied to other cities and larger-scale regions, thereby offering technical and strategic support for SSTD towards carbon–neutral operation.
碳中和目标对污水污泥处理和处置(SSTD)行业提出了重大挑战,需要制定低碳转型的战略规划。然而,支持这一目标的灵活而全面的碳排放分析工具仍然缺乏。本研究提出了一种碳排放分析工具,用于评估 SSTD 的碳排放特征和未来减排潜力。该工具整合了基于生命周期清单(LCI)建模的分析、敏感性分析、回归分析和情景分析。碳排放量根据污泥特性、技术水平和行业外部参数进行动态计算,为因地制宜地进行评估奠定了基础。该框架考虑了行业内外多参数、多角度场景设计变化的潜在影响,实现了动态、全面的模拟。在中国武汉进行的一项案例研究展示了该框架的可用性和应用流程。研究结果表明,如果不采取干预措施,预计从 2021 年到 2060 年,SSTD 的碳排放量将增加一倍以上。在减排措施中,能源和化学品节约将产生最大的减排潜力,其次是技术布局调整和提高能效。污泥行业内外的运营优化贡献最小。采用所有减排措施后,2060 年的排放量可降至-82.91 kt CO2-eq,相当于对污水处理线排放量 13.03% 的补偿。在所有工艺中,焚烧工艺因其当前和未来的低碳排放量而受到推荐。厌氧消化和土地利用的合作资源路线也很有前景,因为随着污泥中有机物和营养物含量的增加,该路线也逐渐显示出优越性能。不同路线的关键因素、子过程和排放类型均已确定,并可进行相应优化。所开发的方法具有足够的灵活性,可应用于其他城市和更大规模的地区,从而为 SSTD 实现碳中和运行提供技术和战略支持。
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引用次数: 0
Reflection on the landscape of education in the area of exposure modelling 对暴露模型领域教育前景的思考
IF 10.3 1区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-01 DOI: 10.1016/j.envint.2024.109103
K.S. Galea , A. Paini , G. Bachler , C. Alejandre-Colomo , P. Fantke , W. Fransman , C. Jung , A. Van Nieuwenhuyse , N. von Goetz , A. Connolly
Exposure models are essential for a range of contexts involving exposure science. The Exposure Models Working Group, established under ISES Europe, identified that to improve model use, suitable training and education is required. However, there is currently no formal educational training programme for exposure modelling in Europe. We present results from an online survey disseminated to the European exposure science community to identify modelling training needs. The questionnaire had three sections: background information about the respondents and interests in exposure science, previous attendance of exposure modelling courses, interest in future training and education in exposure modelling and their coverage and format.
A total of 88 survey recipients completed the survey. Most respondents were from governmental organizations (36 %), with 50 % of all respondents having less than 10 years of experience. About two-thirds of the respondents stated that they had previously attended exposure modelling courses. These were mostly focused on specific models, up to one day in duration and took place in-person. Two thirds of respondents expressed interest in attending future exposure modelling training modules, with the most important topics being interpretation of model results and use of models to meet regulatory standards/requirements. Preferred attendance of training courses was virtual or blended. Costs and certificates of attendance seemed less influential when selecting a training course. Our survey suggests that there is a demand for training in exposure modelling and provides insight to inform the development of training modules that are suitable to fulfil the training needs of exposure scientists and practitioners.
暴露模型对于涉及暴露科学的各种情况至关重要。隶属于 ISES 欧洲分会的暴露模型工作组认为,要提高模型的使用率,需要进行适当的培训和教育。然而,欧洲目前还没有针对暴露模型的正式教育培训计划。为了确定建模培训需求,我们向欧洲暴露科学界发放了一份在线调查问卷,并公布了调查结果。调查问卷包括三个部分:受访者的背景信息和对暴露科学的兴趣、以前参加过的暴露建模课程、对未来暴露建模培训和教育的兴趣及其覆盖范围和形式。大多数受访者来自政府机构(36%),50%的受访者工作经验不足 10 年。约三分之二的受访者表示,他们以前参加过暴露模型课程。这些课程大多以特定模型为重点,持续时间不超过一天,并且是面对面授课。三分之二的受访者表示有兴趣参加今后的暴露模型培训模块,其中最重要的主题是模型结果的解释和使用模型满足监管标准/要求。参加培训课程的首选方式是虚拟培训或混合培训。在选择培训课程时,费用和出席证书似乎影响较小。我们的调查表明,人们对暴露模型培训有需求,并为开发适合满足暴露科学家和从业人员培训需求的培训模块提供了参考。
{"title":"Reflection on the landscape of education in the area of exposure modelling","authors":"K.S. Galea ,&nbsp;A. Paini ,&nbsp;G. Bachler ,&nbsp;C. Alejandre-Colomo ,&nbsp;P. Fantke ,&nbsp;W. Fransman ,&nbsp;C. Jung ,&nbsp;A. Van Nieuwenhuyse ,&nbsp;N. von Goetz ,&nbsp;A. Connolly","doi":"10.1016/j.envint.2024.109103","DOIUrl":"10.1016/j.envint.2024.109103","url":null,"abstract":"<div><div>Exposure models are essential for a range of contexts involving exposure science. The Exposure Models Working Group, established under ISES Europe, identified that to improve model use, suitable training and education is required. However, there is currently no formal educational training programme for exposure modelling in Europe. We present results from an online survey disseminated to the European exposure science community to identify modelling training needs. The questionnaire had three sections: background information about the respondents and interests in exposure science, previous attendance of exposure modelling courses, interest in future training and education in exposure modelling and their coverage and format.</div><div>A total of 88 survey recipients completed the survey. Most respondents were from governmental organizations (36 %), with 50 % of all respondents having less than 10 years of experience. About two-thirds of the respondents stated that they had previously attended exposure modelling courses. These were mostly focused on specific models, up to one day in duration and took place in-person. Two thirds of respondents expressed interest in attending future exposure modelling training modules, with the most important topics being interpretation of model results and use of models to meet regulatory standards/requirements. Preferred attendance of training courses was virtual or blended. Costs and certificates of attendance seemed less influential when selecting a training course. Our survey suggests that there is a demand for training in exposure modelling and provides insight to inform the development of training modules that are suitable to fulfil the training needs of exposure scientists and practitioners.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"193 ","pages":"Article 109103"},"PeriodicalIF":10.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142519946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative study for organophosphate triesters and diesters in mice via oral gavage exposure: Tissue distribution, excreta elimination, metabolites and toxicity 小鼠口服有机磷三酯和二酯的比较研究:组织分布、排泄物消除、代谢物和毒性
IF 10.3 1区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-01 DOI: 10.1016/j.envint.2024.109114
Wenyu Xu , Wei Zhang , Zechen Yu , Xiaoyu Gai , Jie Fu , Ligang Hu , Jianjie Fu , Haiyan Zhang , Guibin Jiang
Organophosphate triesters (tri-OPEs) and diesters (di-OPEs) may threaten human health through dietary intake, whereas little information is available about their fate in mammals. Herein, mice exposure experiments were carried out through gavage with six tri-OPEs and six di-OPEs, respectively. The residual levels of di-OPEs in mice were generally higher than those of tri-OPEs. The residual di-OPEs mainly distributed in the liver and blood while the most tri-OPEs remained in stomach, indicating easier transfer and lower metabolism levels of di-OPEs. The accumulation of tri- and di-OPEs with large octanol–water partition coefficients and long carbon chain were observed in tissues and feces, implying that the elimination of these OPEs through fecal excretion is an important elimination pathway. A total of 86 OPE metabolites were found in murine urine and feces, 57 of which were identified for the first time. For tri-OPEs, carboxylated OPEs had higher peak intensities and fewer interference factors among the metabolites, which could serve as ideal biomarkers. The predicted oral median lethal doses of OPEs and corresponding metabolites showed an increased toxicity of some hydroxylated OPEs and di-OPEs, needing further attention. These results provided new insights and evidence on the fates and biomarkers of OPEs exposure for mammals.
有机磷酸酯三酯类(三-OPEs)和二酯类(二-OPEs)可能会通过饮食摄入威胁人类健康,但有关它们在哺乳动物体内转归的信息却很少。在此,我们分别通过灌胃的方式进行了小鼠接触六种三OPE和六种二OPE的实验。小鼠体内二OPE的残留水平普遍高于三OPE。残留的二-OPEs 主要分布在肝脏和血液中,而大部分三-OPEs 残留在胃中,这表明二-OPEs 更容易转移,代谢水平较低。在组织和粪便中观察到辛醇-水分配系数大、碳链长的三-OPE 和二-OPE 累积,这表明通过粪便排泄是消除这些 OPE 的重要途径。在小鼠的尿液和粪便中总共发现了 86 种 OPE 代谢物,其中 57 种是首次发现。就三OPE而言,羧化OPE的峰强度较高,代谢物之间的干扰因素较少,可作为理想的生物标记物。OPE和相应代谢物的预测口服中位致死剂量显示,一些羟基化OPE和二OPE的毒性增加,需要进一步关注。这些结果为哺乳动物接触 OPEs 的命运和生物标志物提供了新的见解和证据。
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引用次数: 0
Evaluation of the immobilized enzymes function in soil remediation following polycyclic aromatic hydrocarbon contamination 评估固定化酶在多环芳烃污染后土壤修复中的功能
IF 11.8 1区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-29 DOI: 10.1016/j.envint.2024.109106
Babar Hussain, Hongqing Zhu, Chunyu Xiang, Luo Meng Fei, Bowei Zhu, Shibin Liu, Ma Hui, Shengyan Pu
The bioremediation of polycyclic aromatic hydrocarbon (PAHs) from soil utilizing microorganisms, enzymes, microbial consortiums, strains, etc. has attracted a lot of interest due to the environmentally friendly, and cost-effective features. Enzymes can efficiently break down PAHs in soil by hydroxylating the benzene ring, breaking the C–C bond, and catalyze the hydroxylation of a variety of benzene ring compounds via single-electron transfer oxidation. However, the practical application is limited by its instability and ease to loss function under harsh environmental conditions such as pH, temperature, and edaphic stress etc. Therefore, this paper focused on the techniques used to immobilize enzymes and remediate PAHs in soil. Moreover, previous research has not adequately covered this topic, despite the employment of several immobilized enzymes in aqueous solution cultures to remediate other types of organic pollutants. Bibliometric analysis further highlighted the research trends from 2000 to 2023 on this field of growing interest and identified important challenges regarding enzyme stability and interaction with soil matrices. The findings indicated that immobilized enzymes may catalyzed PAHs via oxidation of OH groups in benzene rings, and generate benzyl radicals (i.e., OH and O2) that undergo further reaction and release water. As a result, the intermediate products of PAHs further catalyze by enzyme and enzyme induced microbes producing carbon dioxide and water. Meanwhile efficiency, activity, lifetime, resilience, and sustainability of immobilized enzyme need to be further improved for the large-scale and field-scale clean-up of PAHs polluted soils. This could be possible by integrating enzyme-based with microbial and plant-based remediation strategies. It can be coupled with another line of research focused on using a new set of support materials that can be derived from natural resources.
利用微生物、酶、微生物联合体、菌株等对土壤中的多环芳烃(PAHs)进行生物修复因其环境友好和成本效益高的特点而备受关注。酶可以通过羟化苯环、断裂 C-C 键来有效分解土壤中的多环芳烃,并通过单电子转移氧化催化多种苯环化合物的羟化。然而,由于其不稳定性以及在 pH 值、温度和土壤胁迫等恶劣环境条件下容易丧失功能,其实际应用受到了限制。因此,本文重点关注用于固定酶和修复土壤中多环芳烃的技术。此外,尽管在水溶液培养物中使用了几种固定化酶来修复其他类型的有机污染物,但以往的研究并未充分涵盖这一主题。文献计量学分析进一步强调了从 2000 年到 2023 年这一人们日益关注的领域的研究趋势,并确定了有关酶稳定性和与土壤基质相互作用的重要挑战。研究结果表明,固定化酶可通过氧化苯环中的羟基催化多环芳烃,并生成苄基自由基(即-OH 和-O2),这些自由基会发生进一步反应并释放出水分。因此,多环芳烃的中间产物在酶和酶诱导微生物的催化下进一步产生二氧化碳和水。同时,固定化酶的效率、活性、寿命、复原力和可持续性也需要进一步提高,以便大规模和实地净化多环芳烃污染的土壤。这可以通过将基于酶的方法与基于微生物和植物的修复策略相结合来实现。同时,还可以开展另一项研究,重点是使用一套可从自然资源中提取的新辅助材料。
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引用次数: 0
Activation of persulfate by a layered double oxide supported sulfidated nano zero-valent iron for efficient degradation of 2,2′,4,4′-tetrabromodiphenyl ether in soil 层状双氧化物支撑的硫化纳米零价铁活化过硫酸盐,高效降解土壤中的 2,2′,4,4′-四溴二苯醚
IF 11.8 1区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-28 DOI: 10.1016/j.envint.2024.109098
Yibing Li, Lixun Zhang, Zhengfang Zhang, Yuntao Guan
The nano zero-valent iron (nZVI) activated persulfate (PS) is recognized as a promising approach to degrade 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47), which is ubiquitous in the soil at electronic waste sites. However, all the reported studies were performed in liquids, gaps in the real behaviour and microbial contribution to the degradation of BDE-47 in soil media need to be urgently filled. The removal efficiency of BDE-47 is low using traditional nZVI as activator because of its aggregation and corrosion. Herein, we designed a novel layered double oxide supported sulfidated nano zero-valent iron (S-nZVI@LDO) composite and explored the performance of S-nZVI@LDO/PS to remediate BDE-47 contaminated soil. The results showed that S-nZVI@LDO has excellent stability and superior reduction capability. It could couple PS to achieve a rapid and efficient degradation of BDE-47, and the removal efficiency reached 92.31 % (5 mg/kg) within 6 h, which was much higher than that of n-ZVI/PS (53.38 %) or S-nZVI/PS (75.69 %). The kinetic constant of BDE-47 degradation by S-nZVI@LDO/PS was 23.6 and 3.7 times higher than that by single S-nZVI@LDO and nZVI/PS, respectively. It is attributable to the efficient production of SO4•-, •OH, O2•-, and 1O2 in the system, in which SO4•- and •OH dominated. The bioinformatic analysis demonstrate that soil remediation by S-nZVI@LDO/PS significantly enriched aromatic compounds-degrading bacteria and increased the abundance of hydrocarbon degradation functions. Microbial degradation may play important roles in the BDE-47 degradation and soil quality recovery. The identification of degradation pathways suggests that BDE-47 was degraded to very low-toxic products based on GHS toxicity prediction through a series process of debromination, hydroxylation, cleavage central oxygen, and ring opening, or even completely mineralized. The findings may provide significant implications for the in-situ clean-up of brominated flame retardants in contaminated soil using S-nZVI@LDO/PS Fenton-like system.
纳米零价铁(nZVI)活化过硫酸盐(PS)被认为是降解 2,2′,4,4′-四溴二苯醚(BDE-47)的有效方法。然而,所有已报道的研究都是在液体中进行的,在土壤介质中降解 BDE-47 的真实行为和微生物贡献方面的空白亟待填补。由于 BDE-47 的聚集和腐蚀,使用传统的 nZVI 作为活化剂去除 BDE-47 的效率很低。在此,我们设计了一种新型层状双氧化物支撑硫酸化纳米零价铁(S-nZVI@LDO)复合材料,并探索了 S-nZVI@LDO/PS 修复 BDE-47 污染土壤的性能。结果表明,S-nZVI@LDO 具有优异的稳定性和还原能力。结果表明,S-nZVI@LDO具有良好的稳定性和优异的还原能力,可与PS偶联实现对BDE-47的快速高效降解,6 h内的去除率达到92.31%(5 mg/kg),远高于n-ZVI/PS(53.38%)和S-nZVI/PS(75.69%)。S-nZVI@LDO/PS 降解 BDE-47 的动力学常数分别是单一 S-nZVI@LDO 和 nZVI/PS 的 23.6 倍和 3.7 倍。这归因于系统中 SO4--、-OH、O2--和 1O2 的高效产生,其中 SO4--和 -OH 占主导地位。生物信息学分析表明,S-nZVI@LDO/PS 对土壤的修复显著富集了芳香族化合物降解菌,并增加了碳氢化合物降解功能的丰度。微生物降解可能在 BDE-47 降解和土壤质量恢复中发挥重要作用。降解途径的鉴定表明,根据 GHS 毒性预测,BDE-47 通过脱溴、羟基化、中心氧裂解和开环等一系列过程降解为毒性极低的产物,甚至完全矿化。这些发现可能对利用 S-nZVI@LDO/PS Fenton-like 系统原位净化受污染土壤中的溴化阻燃剂具有重要意义。
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引用次数: 0
Associations of heat with diseases and specific symptoms in Flanders, Belgium: An 8-year retrospective study of general practitioner registration data 比利时佛兰德斯地区高温与疾病和特殊症状的关系:一项为期 8 年的全科医生登记数据回顾性研究
IF 10.3 1区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-24 DOI: 10.1016/j.envint.2024.109097
Endale Alemayehu Ali , Bianca Cox , Karen Van de Vel , Els Verachtert , Bert Vaes , Simon Gabriel Beerten , Elisa Duarte , Charlotte Scheerens , Raf Aerts , Gijs Van Pottelbergh

Introduction

Global temperature rise has become a major health concern. Most previous studies on the impact of heat on morbidity have used hospital data.

Objective

This study aimed to quantify the association between ambient temperature and a variety of potentially heat-related medical conditions and symptoms using general practitioner (GP) data, in Flanders, Belgium.

Methods

We used eight years (2012–2019) of aggregated data of daily GP visits during the Belgian summer period (May-September). A distributed lag nonlinear model (DLNM) with time-stratified conditional quasi-Poisson regression was used to account for the non-linear and delayed effect of temperature indicators (minimum, mean and maximum). We controlled for potential confounders such as particulate matter, humidity, and ozone.

Results

The overall (lag0-14) association between heat and most of the outcomes was J-shaped, with an increased risk of disease observed at higher temperatures. The associations were more pronounced using the minimum temperatures indicator. Comparing the 99th (20 °C) to the minimum morbidity temperature (MMT) of the minimum temperature distribution during summer, the relative risk (RR) was significantly higher for heat-related general symptoms (RR = 1.30 [95 % CI: 1.07, 1.57]), otitis externa (RR = 4.87 [95 % CI:2.98, 7.98]), general heart problems (RR = 2.43 [95 % CI: 1.33, 4.42]), venous problems (RR = 2.48 [95 % CI:1.55, 3.96]), respiratory complaints (RR = 1.97 [95 % CI: 1.25, 3.09]), skin problems (RR = 3.26 [95 % CI: 2.51, 4.25]), and urinary infections (RR = 1.37 [95 % CI: 1.11, 1.69]). However, we did not find evidence for heat-related increases in gastrointestinal problems, cerebrovascular events, cardiovascular events, arrhythmia, mental health problems, upper respiratory problems and lower respiratory problems. An increased risk of allergy was observed when the minimum temperature reached 17.8 °C (RR = 1.50 [95 % CI: 1.23, 1.83]). Acute effects of heat were observed (largest effects at the first few lags).

Summary

Our findings indicated that the occurrence of certain symptoms and illnesses during summer season is associated to high temperature or environmental exposures that are augmented by elevated temperatures. Overall, unlike hospitalization data, GP visits data provide broader population coverage, revealing a more accurate representation of heat-health association.
导言全球气温升高已成为一个主要的健康问题。本研究旨在利用比利时佛兰德斯地区全科医生(GP)的数据,量化环境温度与各种可能与高温有关的病症和症状之间的关联。方法我们使用了比利时夏季(5 月至 9 月)八年(2012 年至 2019 年)全科医生每日就诊的汇总数据。我们采用了分布式滞后非线性模型(DLNM)和时间分层条件准泊松回归,以考虑温度指标(最低气温、平均气温和最高气温)的非线性和延迟效应。我们对颗粒物、湿度和臭氧等潜在混杂因素进行了控制。结果高温与大多数结果之间的总体关联(滞后 0-14 年)呈 "J "形,温度越高,患病风险越高。最低气温指标的相关性更为明显。将夏季最低气温分布的第 99 位(20 °C)与最低发病温度(MMT)进行比较,与高温有关的一般症状(RR = 1.30 [95 % CI: 1.07, 1.57])、外耳道炎(RR = 4.87 [95 % CI:2.98, 7.98])、一般心脏问题(RR = 2.43 [95 % CI:1.33,4.42])、静脉问题(RR = 2.48 [95 % CI:1.55,3.96])、呼吸道不适(RR = 1.97 [95 % CI:1.25,3.09])、皮肤问题(RR = 3.26 [95 % CI:2.51,4.25])和泌尿系统感染(RR = 1.37 [95 % CI:1.11,1.69])。但是,我们没有发现与高温有关的胃肠道问题、脑血管事件、心血管事件、心律失常、精神健康问题、上呼吸道问题和下呼吸道问题增加的证据。当最低气温达到 17.8 °C时,过敏风险增加(RR = 1.50 [95 % CI: 1.23, 1.83])。小结我们的研究结果表明,夏季某些症状和疾病的发生与高温或环境暴露有关,而气温升高会加剧这些症状和疾病。总体而言,与住院数据不同,全科医生就诊数据可提供更广泛的人口覆盖,从而更准确地反映高温与健康的关联。
{"title":"Associations of heat with diseases and specific symptoms in Flanders, Belgium: An 8-year retrospective study of general practitioner registration data","authors":"Endale Alemayehu Ali ,&nbsp;Bianca Cox ,&nbsp;Karen Van de Vel ,&nbsp;Els Verachtert ,&nbsp;Bert Vaes ,&nbsp;Simon Gabriel Beerten ,&nbsp;Elisa Duarte ,&nbsp;Charlotte Scheerens ,&nbsp;Raf Aerts ,&nbsp;Gijs Van Pottelbergh","doi":"10.1016/j.envint.2024.109097","DOIUrl":"10.1016/j.envint.2024.109097","url":null,"abstract":"<div><h3>Introduction</h3><div>Global temperature rise has become a major health concern. Most previous studies on the impact of heat on morbidity have used hospital data.</div></div><div><h3>Objective</h3><div>This study aimed to quantify the association between ambient temperature and a variety of potentially heat-related medical conditions and symptoms using general practitioner (GP) data, in Flanders, Belgium.</div></div><div><h3>Methods</h3><div>We used eight years (2012–2019) of aggregated data of daily GP visits during the Belgian summer period (May-September). A distributed lag nonlinear model (DLNM) with time-stratified conditional quasi-Poisson regression was used to account for the non-linear and delayed effect of temperature indicators (minimum, mean and maximum). We controlled for potential confounders such as particulate matter, humidity, and ozone.</div></div><div><h3>Results</h3><div>The overall (lag0-14) association between heat and most of the outcomes was J-shaped, with an increased risk of disease observed at higher temperatures. The associations were more pronounced using the minimum temperatures indicator. Comparing the 99th (20 °C) to the minimum morbidity temperature (MMT) of the minimum temperature distribution during summer, the relative risk (RR) was significantly higher for heat-related general symptoms (RR = 1.30 [95 % CI: 1.07, 1.57]), otitis externa (RR = 4.87 [95 % CI:2.98, 7.98]), general heart problems (RR = 2.43 [95 % CI: 1.33, 4.42]), venous problems (RR = 2.48 [95 % CI:1.55, 3.96]), respiratory complaints (RR = 1.97 [95 % CI: 1.25, 3.09]), skin problems (RR = 3.26 [95 % CI: 2.51, 4.25]), and urinary infections (RR = 1.37 [95 % CI: 1.11, 1.69]). However, we did not find evidence for heat-related increases in gastrointestinal problems, cerebrovascular events, cardiovascular events, arrhythmia, mental health problems, upper respiratory problems and lower respiratory problems. An increased risk of allergy was observed when the minimum temperature reached 17.8 °C (RR = 1.50 [95 % CI: 1.23, 1.83]). Acute effects of heat were observed (largest effects at the first few lags).</div></div><div><h3>Summary</h3><div>Our findings indicated that the occurrence of certain symptoms and illnesses during summer season is associated to high temperature or environmental exposures that are augmented by elevated temperatures. Overall, unlike hospitalization data, GP visits data provide broader population coverage, revealing a more accurate representation of heat-health association.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"193 ","pages":"Article 109097"},"PeriodicalIF":10.3,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142489202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations of ambient particulate matter and household fuel use with chronic liver disease in China: A nationwide analysis 中国环境颗粒物和家庭燃料使用与慢性肝病的关系:全国性分析
IF 10.3 1区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-23 DOI: 10.1016/j.envint.2024.109083
Yongyue Chen, Chenyu Zhao, Yi Zhang, Yan Lin, Guibin Shen, Nana Wang, Xiaocan Jia, Yongli Yang

Background

Long-term effects of outdoor and indoor air pollution on chronic liver disease (CLD) remain unclear. Thus, the study was conducted to investigate the relationship between prolonged exposure to ambient particulate matter (PM1, PM2.5 and PM10) and household fuel usage with CLD.

Methods

Data from the China Health and Retirement Longitudinal Study (CHARLS) covering the years 2011 to 2020 were employed. In the cross-sectional analysis, 16,680 participants were included, while 12,969 participants were enrolled in the longitudinal study. The associations between various sizes of particulate matter and CLD were elucidated using logistic regression model and generalized linear-mixed models. Additionally, the additive effects of ambient particulate matter (PM) levels and the utilization of solid fuels for cooking were investigated, with a comparison of effect sizes between converted and non-converted fuel types.

Results

Over a 10-year follow-up period, 746 (5.75 %) individuals developed CLD. For a 1-year average concentrations, PM1, PM2.5 and PM10 were each linked to a 1.549 (95 %CI:1.522–1.576), 1.296 (95 %CI:1.276–1.317) and 1.134 (95 %CI:1.118–1.150) fold risk of incident CLD per 10 μg/m3 increase, respectively. A similar effect of PM concentrations over a 2-year period on CLD was observed. Moreover, simultaneous exposure to ambient PM and solid fuels is associated with an increased risk of CLD. Those who continue using solid fuels may face a higher risk of CLD compared to individuals who switch to cleaner cooking fuels. Female participants, smokers, and individuals with shorter sleep duration and multiple chronic diseases exhibited slightly stronger effects.

Conclusion

Long-term exposure to various sizes of PM (PM1, PM2.5, PM10) has been linked to an elevated risk of CLD incidence. Co-exposure to ambient PM and solid fuels is associated with higher health risks.
背景室外和室内空气污染对慢性肝病(CLD)的长期影响尚不清楚。因此,本研究对长期暴露于环境颗粒物(PM1、PM2.5 和 PM10)和家庭燃料使用与慢性肝病之间的关系进行了调查。方法采用中国健康与退休纵向研究(CHARLS)2011 年至 2020 年的数据。在横断面分析中,纳入了 16,680 名参与者,而在纵向研究中纳入了 12,969 名参与者。研究采用逻辑回归模型和广义线性混合模型阐明了各种粒径的颗粒物与慢性阻塞性肺病之间的关系。此外,研究还调查了环境颗粒物(PM)水平和使用固体燃料做饭的叠加效应,并比较了转换燃料和未转换燃料类型之间的效应大小。就 1 年的平均浓度而言,PM1、PM2.5 和 PM10 每增加 10 μg/m3 分别与 1.549(95 %CI:1.522-1.576)、1.296(95 %CI:1.276-1.317)和 1.134(95 %CI:1.118-1.150)倍的 CLD 发病风险有关。在为期两年的时间里,可吸入颗粒物浓度对慢性肺部疾病也有类似的影响。此外,同时接触环境中的可吸入颗粒物和固体燃料会增加慢性肺部疾病的风险。与改用清洁烹饪燃料的人相比,继续使用固体燃料的人可能面临更高的慢性慢性阻塞性肺病风险。女性参与者、吸烟者以及睡眠时间较短和患有多种慢性疾病的人受到的影响略大。同时暴露于环境可吸入颗粒物和固体燃料与更高的健康风险有关。
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引用次数: 0
Effects of microplastics on the rheological properties of sediment slurries in aquatic environments 微塑料对水生环境中沉积泥浆流变特性的影响
IF 10.3 1区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-23 DOI: 10.1016/j.envint.2024.109095
Jiaqi Zhang, Clarence Edward Choi, Feihong Gao
Sediment slurries, characterized by their high concentrations of fine-grained cohesive sediment, are prevalent in various aquatic environments, including fluid mud, sediment gravity flows, and dredging slurries. Abundant microplastics have been detected in sediment slurries, which indicates that these slurries function as carriers for the transport of microplastics. However, there is a dearth of understanding on how sediment slurries transport microplastics. To ascertain the transport mechanisms, elucidating the effects of microplastics on the rheological properties of sediment slurries is a prerequisite because these properties govern the flow dynamics and mobility of such slurries. This study conducts experimental and theoretical investigations to examine, interpret, and quantify the effects of microplastics on the rheological properties of sediment slurries. Microplastics are shown to increase the yield stress and viscosity of sediment slurries via enhancing sediment aggregation. A new descriptor, specifically, the effective volume fraction, is proposed to characterize the effects of microplastics on sediment aggregation. Based on the newly-proposed descriptor, a new analytical model is proposed to predict the yield stress and viscosity of sediment slurries with microplastics. This study lays a foundation for further interpretating the flow dynamics and thus the transport processes of sediment slurries laden with microplastics.
沉积泥浆的特点是含有大量细粒粘性沉积物,普遍存在于各种水生环境中,包括流体泥浆、沉积物重力流和疏浚泥浆。在沉积泥浆中检测到了大量微塑料,这表明这些泥浆具有运输微塑料的载体功能。然而,人们对沉积泥浆如何迁移微塑料还缺乏了解。要确定其迁移机制,就必须阐明微塑料对沉积物泥浆流变特性的影响,因为这些特性会影响此类泥浆的流动动力学和流动性。本研究通过实验和理论研究来检查、解释和量化微塑料对沉积泥浆流变特性的影响。研究表明,微塑料可通过增强沉积物的聚集来提高沉积泥浆的屈服应力和粘度。为描述微塑料对沉积物聚集的影响,提出了一种新的描述指标,特别是有效体积分数。根据新提出的描述因子,提出了一个新的分析模型来预测含有微塑料的沉积泥浆的屈服应力和粘度。这项研究为进一步解释含有微塑料的沉积泥浆的流动动力学进而解释其迁移过程奠定了基础。
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引用次数: 0
期刊
Environment International
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