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2019 IEEE 32nd International Symposium on Computer-Based Medical Systems (CBMS)最新文献

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Sequence Time Expression Recognition in the Spanish Clinical Narrative 西班牙临床叙事中的序列时间表达识别
Pub Date : 2019-06-01 DOI: 10.1109/CBMS.2019.00074
Alejandro Ruiz-de-laCuadra, J. L. L. Cuadrado, I. González-Carrasco, B. Ruíz-Mezcua
Time expression recognition is one of the open issues in Natural Language Processing. These expressions are relevant to determine temporal aspects of the text as well as to establish relationships among facts described in said text. In the clinical domain, the temporal aspects are relevant to determine, for example, a sequence of facts in a clinical history. This paper presents research on the recognition of time expressions in Spanish according to the TIMEX3 standard. First, we establish HeidelTime, a well-known state of the art rule-based system, as a reference. Next, a hybrid model (a combination of bidirectional LSTM, CNN and CRF) is introduced to try to improve the results for the Spanish language. Both architectures have been tested with a Timex3 annotated Spanish corpus (TIMEBANK 1.0) to compare them. First, the results obtained show that the neural architecture obtains better results in Spanish. Finally, the neural architecture has been tested on a corpus of Clinical Notes (English and Spanish) in order to determine the results on this domain.
时间表达式识别是自然语言处理领域的一个开放性问题。这些表达与确定文本的时间方面以及在所述文本中描述的事实之间建立关系有关。在临床领域,时间方面与确定有关,例如,临床病史中的一系列事实。本文根据TIMEX3标准对西班牙语中时间表达式的识别进行了研究。首先,我们建立了一个著名的基于规则的系统HeidelTime作为参考。接下来,引入一个混合模型(双向LSTM, CNN和CRF的组合)来尝试改善西班牙语的结果。这两种体系结构都用一个Timex3注释的西班牙语语料库(TIMEBANK 1.0)进行了测试,以比较它们。首先,实验结果表明,该神经结构在西班牙语学习中取得了较好的效果。最后,在临床笔记语料库(英语和西班牙语)上对神经结构进行了测试,以确定该领域的结果。
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引用次数: 1
Radiomics Textural Features Extracted from Subcortical Structures of Grey Matter Probability for Alzheimers Disease Detection. 从灰质皮层下结构提取辐射组学纹理特征用于阿尔茨海默病的检测。
Pub Date : 2019-06-01 DOI: 10.1109/CBMS.2019.00084
César Antonio Ortiz Toro, Nuria Gutiérrez Sánchez, C. Gonzalo-Martín, Roberto Garrido García, A. R. González, Ernestina Menasalvas Ruiz
Alzheimer's disease (AD) is characterized by a progressive deterioration of cognitive and behavioral functions as a result of the atrophy of specific regions of the brain. It is estimated that by 2050 there will be 131.5 million people affected. Thus, there is an urgent need to find biological markers for its early detection and monitoring. In this work, it is present an analysis of textural radiomics features extracted from a gray matter probability volume, in a set of individual subcortical regions, from a number of different atlases, to identify subject with AD in a MRI. Also, significant subcortical regions for AD detection have been identified using a ReliefF relevance test. Experimental results using the ADNI1 database have proven the potential of some of the tested radiomic features as possible biomarkers for AD/CN differentiation.
阿尔茨海默病(AD)的特征是由于大脑特定区域的萎缩导致认知和行为功能的进行性恶化。据估计,到2050年将有1.315亿人受到影响。因此,迫切需要寻找早期发现和监测的生物标志物。在这项工作中,它提出了从灰质概率体积中提取的纹理放射组学特征的分析,在一组单独的皮层下区域,从许多不同的地图集,在MRI中识别AD受试者。此外,使用ReliefF相关测试确定了AD检测的重要皮层下区域。使用ADNI1数据库的实验结果证明了一些测试的放射学特征可能作为AD/CN分化的生物标志物。
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引用次数: 2
Software Architecture for Health Care Supportive Home Systems to Assist Patients with Diabetes Mellitus 帮助糖尿病患者的健康护理支持家庭系统的软件架构
Pub Date : 2019-06-01 DOI: 10.1109/CBMS.2019.00060
Lina Garcés, I. Vicente, E. Nakagawa
Diabetes Mellitus is a life-long health condition that causes a high concentration of glucose in the blood. The foundation of the treatment and prevention of diabetes lays on reeducation and medication to prevent complications caused by high levels of glucose in the blood. New methods, products, and services, like those provided by the Ambient Assisted Living (AAL) domain, for supporting activities of the daily life of people with chronic diseases are effective to assist the management of diabetes disease. Particularly, Health Care Supportive Home (HSH) systems can provide an autonomous life in their residence to patients and supply them with autonomy through the use of different types of technologies. We present the software architecture of DiaManT@Home, a service-oriented HSH system that assists patients diagnosed with diabetes mellitus, and that enhances the self-management of their condition at home. DiaManT@Home was constructing following a well-established process based on the instantiation of a reference architecture for HSH systems. The software architecture of DiaManT@Home was assessed regarding the completeness of its software elements to achieve functional and non-functional requirements using prototypes. Results showed that DiaManT@Home can be considered as a complete solution to an HSH system for assisting patients at home. As future works, DiaManT@Home will be coded following the architecture presented in this work.
糖尿病是一种导致血液中葡萄糖浓度过高的终生健康状况。糖尿病的治疗和预防的基础是再教育和药物治疗,以防止高血糖引起的并发症。新的方法、产品和服务,如由环境辅助生活(AAL)领域提供的,用于支持慢性病患者日常生活的活动,对协助糖尿病疾病的管理是有效的。特别是,卫生保健支持家庭(HSH)系统可以通过使用不同类型的技术为患者提供自主生活。我们提出了DiaManT@Home的软件架构,这是一个面向服务的HSH系统,可以帮助糖尿病患者诊断,并增强他们在家中对病情的自我管理。DiaManT@Home是根据HSH系统参考体系结构实例化的完善过程构建的。DiaManT@Home的软件架构是根据其软件元素的完整性来评估的,以使用原型实现功能和非功能需求。结果表明,DiaManT@Home可以被认为是一个完整的解决方案,以协助病人在家里的HSH系统。在未来的工作中,DiaManT@Home将按照本工作中提供的架构进行编码。
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引用次数: 3
Predicting Diabetes in Healthy Population through Machine Learning 通过机器学习预测健康人群的糖尿病
Pub Date : 2019-06-01 DOI: 10.1109/CBMS.2019.00117
H. Abbas, L. Alic, M. Rios, M. Abdul-Ghani, K. Qaraqe
In this paper, we revisit the data of the San Antonio Heart Study, and employ machine learning to predict the future development of type-2 diabetes. To build the prediction model, we use the support vector machines and ten features that are wellknown in the literature as strong predictors of future diabetes. Due to the unbalanced nature of the dataset in terms of the class labels, we use 10-fold cross-validation to train the model and a hold-out set to validate it. The results of this study show a validation accuracy of 84.1% with a recall rate of 81.1% averaged over 100 iterations. The outcomes of this study can help in identifying the population that is at high risk of developing type-2 diabetes in the future.
在本文中,我们回顾了圣安东尼奥心脏研究的数据,并利用机器学习来预测2型糖尿病的未来发展。为了建立预测模型,我们使用了文献中众所周知的支持向量机和十个特征作为未来糖尿病的强预测因子。由于数据集在类标签方面的不平衡性质,我们使用10倍交叉验证来训练模型,并使用一个保留集来验证它。研究结果表明,100次迭代的平均召回率为81.1%,验证准确率为84.1%。这项研究的结果可以帮助确定未来患2型糖尿病的高风险人群。
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引用次数: 26
Infection Diagnosis using Biomedical Signals in Small Data Scenarios 小数据环境下生物医学信号的感染诊断
Pub Date : 2019-06-01 DOI: 10.1109/CBMS.2019.00018
Alejandro Baldominos Gómez, H. Oğul, Ricardo Colomo Palacios
Being able to detect an infection at an early stage is a clinical problem of the utmost importance. An infection not diagnosed on time might not only severely affect the infected patient's health, but also to spread and start a focus of contagion to other people. In this paper, we propose a clinical decision support system to automatically diagnose infections using physiological signals from the patients. The focus of the system is put on being able to deal with very small amounts of data (one aggregated record per patient and day), which eases the potential of the system in environments with low resources. Data has been acquired between April 2018 and January 2019 in two nursing homes in Spain, where nurses had also tested patients for infections. Machine learning models have then been created by aggregating measurements from days prior to the infection (lead) and after the infection started (lag) in order to generate features. The best model attained reports an AUROC of 0.722, using data from up to two days after the infection started. Interestingly, an AUROC of up to 0.692 is achieved when infection prognosis is considered; i.e., using only measurements prior to the manual recording of the infection to compose the dataset.
能够在早期阶段发现感染是一个至关重要的临床问题。如果不及时诊断,不仅会严重影响患者的健康,还可能传播并成为他人的传染源。在本文中,我们提出了一个临床决策支持系统来自动诊断感染从患者的生理信号。该系统的重点是能够处理非常少量的数据(每个患者每天一个汇总记录),这降低了系统在资源不足环境中的潜力。2018年4月至2019年1月期间,在西班牙的两家养老院获得了数据,那里的护士也对患者进行了感染检测。然后,通过汇总感染前几天(lead)和感染开始后(lag)的测量数据来创建机器学习模型,以生成特征。使用感染开始后两天的数据,最佳模型获得的AUROC报告为0.722。有趣的是,当考虑感染预后时,AUROC高达0.692;即,仅使用人工记录感染之前的测量值来组成数据集。
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引用次数: 4
Usability and Cognitive Benefits of a Serious Game to Combat Aedes Aegypti Mosquito 一款对抗埃及伊蚊的严肃游戏的可用性和认知益处
Pub Date : 2019-06-01 DOI: 10.1109/CBMS.2019.00145
Igor W. S. Falcão, D. Souza, Fabiola Araujo, J. Fernandes, Y. Pires, D. Cardoso, Marcos C. R. Seruffo
The development of systems that aim to spread public information, for example, public awareness campaigns for spotting the signs and symptoms of infectious diseases and how to prevent them, should be addressed by human-computer interaction, or more specifically, by devising interfaces that have a high degree of usability or user-friendliness. This paper examines a serious game that aims at providing people with the means of preventing diseases transmitted by the Aedes aegypti mosquito. An empirical test with groups of users was carried out to validate and observe the benefits of the game. The first group answered some questions about the diseases and how to combat the Aedes aegypti proliferation without playing the game and the second group answered the same questions after having played the game. The results showed a significant increase in the knowledge of Aedes aegypti and the diseases transmitted by it. As well as seeking to play the game to spread information about this disease, the purpose of this study is to understand the user's experience by interacting with a serious game and assisting in the evaluation of the usability and the cognitive benefits of serious games.
发展旨在传播公共信息的系统,例如,关于发现传染病的迹象和症状以及如何预防传染病的公众认识运动,应通过人机交互,或更具体地说,通过设计高度可用性或用户友好的界面来解决。本文研究了一个严肃的游戏,旨在为人们提供预防由埃及伊蚊传播的疾病的手段。我们对用户群体进行了实证测试,以验证和观察游戏的好处。第一组在不玩游戏的情况下回答了一些关于疾病和如何对抗埃及伊蚊扩散的问题,第二组在玩了游戏后回答了同样的问题。调查结果显示,人们对埃及伊蚊及其传播疾病的认识有了显著提高。除了试图通过玩游戏来传播有关这种疾病的信息外,本研究的目的是通过与严肃游戏互动来了解用户的体验,并协助评估严肃游戏的可用性和认知益处。
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引用次数: 1
Exploring Machine Learning Algorithms to Identify Heart Failure Patients: the Tuscany Region Case Study 探索机器学习算法识别心力衰竭患者:托斯卡纳地区案例研究
Pub Date : 2019-06-01 DOI: 10.1109/CBMS.2019.00088
Silvia Panicacci, M. Donati, L. Fanucci, I. Bellini, F. Profili, P. Francesconi
Heart failure patients have become an important challenge for the healthcare system, since they represent a medical, social and economic problem. Early heart failure diagnoses can be very useful to improve patients' quality of life and to reduce the resources consumption, but they can be complex for the general practitioners. Data mining and machine learning techniques can really help in this field. The aim of this study is to validate some machine learning models to identify heart failure patients, starting from administrative data, and to make them transparent and interpretable. Despite the lack of clinical data, not available in Italy, but the most employed for the identification of heart failure patients, the results are comparable with the state-of-the-art ones and the models outperform the performances already obtained in Tuscany.
心力衰竭患者已经成为医疗保健系统的一个重要挑战,因为他们代表了一个医疗、社会和经济问题。早期心力衰竭诊断对提高患者的生活质量和减少资源消耗非常有用,但对全科医生来说可能很复杂。数据挖掘和机器学习技术确实可以在这个领域提供帮助。本研究的目的是验证一些机器学习模型来识别心力衰竭患者,从管理数据开始,并使其透明和可解释。尽管缺乏临床数据,无法在意大利获得,但大多数用于心力衰竭患者的识别,结果可与最先进的模型相媲美,并且模型的性能优于托斯卡纳已经获得的性能。
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引用次数: 1
Wikipedia Disease Articles: An Analysis of their Content and Evolution 维基百科疾病文章:其内容和演变分析
Pub Date : 2019-06-01 DOI: 10.1109/CBMS.2019.00136
Gerardo Lagunes García, Lucía Prieto Santamaría, Eduardo P. García del Valle, M. Zanin, Ernestina Menasalvas Ruiz, A. R. González
Nowadays there is a huge amount of medical information that can be retrieved from different sources, both structured and unstructured. Internet has plenty of textual sources with medical knowledge (books, scientific papers, specialized web pages, etc.), but not all of them are publicly available. Wikipedia is a free, open and worldwide accessible source of knowledge. It contains more than 150,000 articles of medical content in the form of texts (non-structured information) that can be mined. The aim of this work is to study whether the evolution of information contained in Wikipedia medical articles can be used in a research context. The study has been focused on extracting the elements, from Wikipedia disease articles, that can be used to guide a diagnosis process, support the creation of diagnostic systems, or analyze the similarities between diseases, among others.
现在有大量的医学信息可以从不同的来源检索,包括结构化和非结构化。互联网上有大量医学知识的文本来源(书籍、科学论文、专业网页等),但并非所有这些都是公开的。维基百科是一个免费的、开放的、全世界都可以访问的知识来源。它包含超过15万篇可以挖掘的文本形式的医学内容(非结构化信息)。这项工作的目的是研究维基百科医学文章中包含的信息的演变是否可以用于研究背景。这项研究的重点是从维基百科疾病文章中提取可用于指导诊断过程、支持创建诊断系统或分析疾病之间的相似性等的元素。
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引用次数: 2
An Objective Measure of Carotid Disease Based on a Multiparameter Approach 基于多参数方法的颈动脉疾病客观测量
Pub Date : 2019-06-01 DOI: 10.1109/CBMS.2019.00121
Laura Verde, G. Pietro
Atherosclerosis is a multifactorial disease that affects a significant number of people during their lifetime. It is a pathology clinically silent for years that develops with a gradual thickening of the vessel walls and a consecutive formation of plaque. This is the cause of several dangerous conditions such as ischemic stroke, the most common cause of stroke in middle-aged people. To avoid and reduce these events a continuos and meticulous monitoring of patients with any carotid diseases is necessary. This paper presents an objective measure of the progression of a carotid patology. An index capable of distinguishing between the initial state of thickening of the carotid arterial walls and the successive presence of more serious plaque has been defined. The presence of thickening or plaque is estimated by evaluating Heart Rate Variability. This is a non-invasive approach, able to estimate characteristic parameters in an easy and efficient way, constituting an accurate and optimum instrument for a real-time continuous monitoring. Locally Weighted Learning has been used to automatically find a relationship between these parameters and the presence of a disorder, tested on an available dataset.
动脉粥样硬化是一种影响许多人一生的多因素疾病。它是一种多年的病理临床沉默,随着血管壁逐渐增厚和斑块的连续形成而发展。这是导致缺血性中风等几种危险情况的原因,缺血性中风是中年人中风的最常见原因。为了避免和减少这些事件,有必要对任何颈动脉疾病患者进行持续细致的监测。本文提出了一种客观的测量颈动脉病理进展的方法。已经定义了一个能够区分颈动脉壁增厚的初始状态和更严重斑块的连续存在的指标。通过评估心率变异性来估计增厚或斑块的存在。这是一种无创的方法,能够以简单有效的方式估计特征参数,构成实时连续监测的准确和最佳仪器。局部加权学习已被用于自动找到这些参数与无序存在之间的关系,并在可用的数据集上进行了测试。
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引用次数: 0
PULSE: Participatory Urban Living for Sustainable Environment PULSE:可持续环境的参与式城市生活
Pub Date : 2019-06-01 DOI: 10.1109/CBMS.2019.00022
M. Ottaviano, M. Cabrera-Umpiérrez, M. Arredondo
The paper presents the Pulse project, a European project founded under the Horizon 2020 program.
这篇论文介绍了Pulse项目,这是一个在“地平线2020”计划下成立的欧洲项目。
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引用次数: 2
期刊
2019 IEEE 32nd International Symposium on Computer-Based Medical Systems (CBMS)
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