Cell-cultured meat (CM), a meat alternative derived from animal cells grown in a lab using tissue-engineering techniques, is often presented as equivalent to conventional meat but produced more sustainably. Consumer acceptance of CM has been widely investigated and promoted through optimistic framing. Very few, if any, studies present potential, realistic downsides of CM or let consumers express their thoughts through open-ended questions. The current study examines the effect of information framing on consumers' closed and open-ended responses to CM. Through an online survey, adults (N = 1003, U.S.) were presented with either an ‘optimistic’ or ‘pessimistic’ information framing for CM, and responded to a series of closed- and open-ended questions. Natural Language Processing was applied to open-ended responses (sentiment analysis, topic modeling), and closed-ended responses were compared via and Mann-Whitney U tests. As expected, optimistic framing increased openness to CM: those in the ‘optimistic’ group were more likely to try and buy CM (p < 0.05), with open-ended responses showing curiosity to compare CM to conventional meat and/or try something new, interest in sustainability, and concern for animal welfare. Conversely, a ‘pessimistic’ information framing reduced consumer interest to try and buy CM (p < 0.05), with open-ended responses indicating unfamiliarity, concerns over ‘altered’ or ‘risky’ foods, and a perception of ‘fake’ meat explaining these responses. By comparing multiple framings and response types, this study helps CM researchers to better understand consumer responses and identify potential barriers and supports to product adoption.
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