Waode Rustiah, Andi Fatmawati, Dewi Arisanti, Muawanah Muawanah, Nuraedah Hasima
Camellia sinensis L. atau yang lebih dikenal daun teh hijau sudah lama digunakan sebagai obat herbal dan juga bisa dijadikan olahan produk makanan maupun minuman. Kandungan polifenol, katekin, dan tanin yang memiliki aktivitas antibakteri. Penelitian ini bertujuan untuk mengetahui perasan teh celup (Camellia sinensis L.) dalam menghambat pertumbuhan bakteri Staphylococcus aureus. Penelitian ini dilaksanakan secara eksperimen laboratorik dengan variasi konsentrasi, yaitu 25%, 50%, dan 75% serta larutan pembanding kontrol positif (antibiotic tetracycline) dan larutan pembanding kontrol negatif (aquabides), dengan masa inkubasi selama 24 jam pada suhu 370C. Sampel dalam penilitian ini adalah perasan teh hijau celup (Camellia sinensis L.) menggunakan metode difusi agar berlapis. Berdasarkan hasil penelitian pada konsentrasi 25%, 50% dan 75% tidak memiliki zona hambat. Pada kontrol negatif memiliki zona hambat 0 mm sedangkan kontrol positif memiliki zona hambat 20,2 mm. Hasil penelitian ini menunjukkan bahwa perasan teh celup tidak efektif menghambat pertumbuhan bakteri Staphylococcus aureus
{"title":"UJI EFEKTIVITAS PERASAN TEH (Camellia sinensis L.) CELUP TERHADAP Staphylococcusaureus","authors":"Waode Rustiah, Andi Fatmawati, Dewi Arisanti, Muawanah Muawanah, Nuraedah Hasima","doi":"10.53861/jmed.v7i2.293","DOIUrl":"https://doi.org/10.53861/jmed.v7i2.293","url":null,"abstract":"Camellia sinensis L. atau yang lebih dikenal daun teh hijau sudah lama digunakan sebagai obat herbal dan juga bisa dijadikan olahan produk makanan maupun minuman. Kandungan polifenol, katekin, dan tanin yang memiliki aktivitas antibakteri. Penelitian ini bertujuan untuk mengetahui perasan teh celup (Camellia sinensis L.) dalam menghambat pertumbuhan bakteri Staphylococcus aureus. Penelitian ini dilaksanakan secara eksperimen laboratorik dengan variasi konsentrasi, yaitu 25%, 50%, dan 75% serta larutan pembanding kontrol positif (antibiotic tetracycline) dan larutan pembanding kontrol negatif (aquabides), dengan masa inkubasi selama 24 jam pada suhu 370C. Sampel dalam penilitian ini adalah perasan teh hijau celup (Camellia sinensis L.) menggunakan metode difusi agar berlapis. Berdasarkan hasil penelitian pada konsentrasi 25%, 50% dan 75% tidak memiliki zona hambat. Pada kontrol negatif memiliki zona hambat 0 mm sedangkan kontrol positif memiliki zona hambat 20,2 mm. Hasil penelitian ini menunjukkan bahwa perasan teh celup tidak efektif menghambat pertumbuhan bakteri Staphylococcus aureus","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84300804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Rasyid, M. Muawanah, Hasnah Hasnah, Septiana Septiana
Sakarin dan siklamat merupakan pemanis yang sering digunakan oleh industri rumahan, karena harganya relatif murah dan dapat memberikan rasa manis yang lebih tinggi dibandingkan pemanis alami. Air tahu merupakan salah satu industri rumahan yang terbuat dari hasil ekstraksi kedelai yang memiliki rasa tidak manis sehingga pemanis buatan ditambahkan untuk meningkatkan cita rasa. Namun, pemakaian pemanis secara berlebih dapat menyebabkan efek samping yakni mengganggu sistem pencernaan, sakit kepala, migrain, tremor, diare, kehilangan daya ingat, kanker kandung kemih, pengecilan testicular dan kerusakan kromosom. Penelitian ini bertujuan untuk mengidentifikasi sakarin dan siklamat pada air tahu. Jenis penelitian observasi laboratorik sebanyak 5 sampel menggunakan metode uji warna untuk sakarin dan metode pengendapan untuk siklamat. Dari hasil penelitian yang dilakukan terhadap 5 sampel diperoleh sampel positif mengandung siklamat ditandai adanya endapan putih seperti pada kontrol positif dan negatif mengandung sakarin yang ditandai dengan tidak terjadinya perubahan warna hijau flouresens. Hasil penelitian yang telah dilakukan menunjukkan bahwa dari 5 sampel air tahu yang digunakan diperoleh 5 sampel yang mengandung siklamat dan 5 sampel tidak mengandung sakarin.
{"title":"ANALISIS KUALITATIF PEMANIS BUATAN SAKARIN DAN SIKLAMAT PADA AIR TAHU","authors":"N. Rasyid, M. Muawanah, Hasnah Hasnah, Septiana Septiana","doi":"10.53861/jmed.v7i2.344","DOIUrl":"https://doi.org/10.53861/jmed.v7i2.344","url":null,"abstract":"Sakarin dan siklamat merupakan pemanis yang sering digunakan oleh industri rumahan, karena harganya relatif murah dan dapat memberikan rasa manis yang lebih tinggi dibandingkan pemanis alami. Air tahu merupakan salah satu industri rumahan yang terbuat dari hasil ekstraksi kedelai yang memiliki rasa tidak manis sehingga pemanis buatan ditambahkan untuk meningkatkan cita rasa. Namun, pemakaian pemanis secara berlebih dapat menyebabkan efek samping yakni mengganggu sistem pencernaan, sakit kepala, migrain, tremor, diare, kehilangan daya ingat, kanker kandung kemih, pengecilan testicular dan kerusakan kromosom. Penelitian ini bertujuan untuk mengidentifikasi sakarin dan siklamat pada air tahu. Jenis penelitian observasi laboratorik sebanyak 5 sampel menggunakan metode uji warna untuk sakarin dan metode pengendapan untuk siklamat. Dari hasil penelitian yang dilakukan terhadap 5 sampel diperoleh sampel positif mengandung siklamat ditandai adanya endapan putih seperti pada kontrol positif dan negatif mengandung sakarin yang ditandai dengan tidak terjadinya perubahan warna hijau flouresens. Hasil penelitian yang telah dilakukan menunjukkan bahwa dari 5 sampel air tahu yang digunakan diperoleh 5 sampel yang mengandung siklamat dan 5 sampel tidak mengandung sakarin.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84219825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-27DOI: 10.30659/sainsmed.v13i2.29137
Yulice Soraya Nur Intan, Hanif Reza, Robby Gunawan
Polycystic ovary syndrome (PCOS) is a hormonal disorder that affects women of reproductive age. It is characterised by several clinical signs and symptoms, including hyperandrogenism, ovarian dysfunction, and chronic anovulation. Obesity and hormonal imbalances can be reduced in PCOS by modifying lifestyle habits. The effects of lifestyle changes on PCOS were investigated, and it was found that consuming less fat and engaging in physical activity reduced metabolic disturbances. The purpose of this study was to examine the effects of lifestyle modifications on metabolic parameters, anthropometric parameters, and the hirsutism score as they relate to the pathogenesis of PCOS. This study involved a total of 10 patients diagnosed with PCOS at the Sultan Agung Semarang Islamic Hospital. Blood glucose, triglycerides, HDL (high density lipoprotein), blood pressure, waist circumference, hirsutism score, and vital sign data related to PCOS were measured before and after a 4-month treatment. PCOS patients' fasting blood sugar levels, triglycerides (TG), high density lipoprotein (HDL), hirsutism scores, blood pressure (systolic and diastolic), and waist circumference averaged 92, 60; 48.10; 96.90; 10.5; 121.5/77; 86.80, respectively, at baseline (pretreatment). After four months of treatment, the average levels of fasting blood sugar, triglycerides, high-density lipoproteins, blood pressure (systolic and diastolic), hirsutism scores, and waist circumference were 108.7, 50, 99.8, 7, 122.3, 82.7, and 87.50, respectively. Changes in lifestyle led to significant variations in fasting blood sugar levels as a metabolic parameter and hirsutism scores, but not in triglycerides, high-density lipoprotein, waist circumference, or blood pressure.
{"title":"The effect of lifestyle modification on metabolic, anthropometric parameters and hirsutism score in polycystic ovary syndrome","authors":"Yulice Soraya Nur Intan, Hanif Reza, Robby Gunawan","doi":"10.30659/sainsmed.v13i2.29137","DOIUrl":"https://doi.org/10.30659/sainsmed.v13i2.29137","url":null,"abstract":"Polycystic ovary syndrome (PCOS) is a hormonal disorder that affects women of reproductive age. It is characterised by several clinical signs and symptoms, including hyperandrogenism, ovarian dysfunction, and chronic anovulation. Obesity and hormonal imbalances can be reduced in PCOS by modifying lifestyle habits. The effects of lifestyle changes on PCOS were investigated, and it was found that consuming less fat and engaging in physical activity reduced metabolic disturbances. The purpose of this study was to examine the effects of lifestyle modifications on metabolic parameters, anthropometric parameters, and the hirsutism score as they relate to the pathogenesis of PCOS. This study involved a total of 10 patients diagnosed with PCOS at the Sultan Agung Semarang Islamic Hospital. Blood glucose, triglycerides, HDL (high density lipoprotein), blood pressure, waist circumference, hirsutism score, and vital sign data related to PCOS were measured before and after a 4-month treatment. PCOS patients' fasting blood sugar levels, triglycerides (TG), high density lipoprotein (HDL), hirsutism scores, blood pressure (systolic and diastolic), and waist circumference averaged 92, 60; 48.10; 96.90; 10.5; 121.5/77; 86.80, respectively, at baseline (pretreatment). After four months of treatment, the average levels of fasting blood sugar, triglycerides, high-density lipoproteins, blood pressure (systolic and diastolic), hirsutism scores, and waist circumference were 108.7, 50, 99.8, 7, 122.3, 82.7, and 87.50, respectively. Changes in lifestyle led to significant variations in fasting blood sugar levels as a metabolic parameter and hirsutism scores, but not in triglycerides, high-density lipoprotein, waist circumference, or blood pressure.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79726906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hemoglobin (Hb) level is a biochemical indicator of the nutritional status of pregnant women, and a low Hb level reduces blood supply to the placenta, which influences the incidence of placenta previa. A placenta previa develops in the lower portion of the uterus, completely or partially expanding to cover the entire birth canal and the internal uterine ostium. The APGAR score is commonly used as a predictor of infant mortality and long-term disability and as an indicator of infant health at birth. The risk of maternal and infant mortality and morbidity increases in placenta previa patients with inadequate vascularization, which can be caused by low Hb levels. This study aimed to determine the relationship between Hb levels and APGAR scores in patients with placenta previa at Sultan Agung Islamic Hospital in Semarang. This analytic observation study is a cross-sectional analysis with purposive sampling method. From January 2017 to January 2018, all placenta previa patients hospitalized at Sultan Agung Hospital in Semarang were included in this study. In this study, we used subject data that met the criteria for inclusion. The p-value derived from the chi-square analysis is 0.041 (p< 0.05). A test of association was conducted. This test revealed that the OR was 11.5 (OR > 1). Low Hb levels (11 g/dl) could significantly increase the risk of a lower APGAR score at 5 min in patients with placenta previa who have a low Hb level.
{"title":"The association between Hb levels in placenta previa patients with apgar scores","authors":"Herlin Ajeng Nurrahma, Yulice Soraya Nur Intan, Andreanita Meliala, Paramita Narwidina","doi":"10.30659/sainsmed.v13i2.26623","DOIUrl":"https://doi.org/10.30659/sainsmed.v13i2.26623","url":null,"abstract":"Hemoglobin (Hb) level is a biochemical indicator of the nutritional status of pregnant women, and a low Hb level reduces blood supply to the placenta, which influences the incidence of placenta previa. A placenta previa develops in the lower portion of the uterus, completely or partially expanding to cover the entire birth canal and the internal uterine ostium. The APGAR score is commonly used as a predictor of infant mortality and long-term disability and as an indicator of infant health at birth. The risk of maternal and infant mortality and morbidity increases in placenta previa patients with inadequate vascularization, which can be caused by low Hb levels. This study aimed to determine the relationship between Hb levels and APGAR scores in patients with placenta previa at Sultan Agung Islamic Hospital in Semarang. This analytic observation study is a cross-sectional analysis with purposive sampling method. From January 2017 to January 2018, all placenta previa patients hospitalized at Sultan Agung Hospital in Semarang were included in this study. In this study, we used subject data that met the criteria for inclusion. The p-value derived from the chi-square analysis is 0.041 (p< 0.05). A test of association was conducted. This test revealed that the OR was 11.5 (OR > 1). Low Hb levels (11 g/dl) could significantly increase the risk of a lower APGAR score at 5 min in patients with placenta previa who have a low Hb level.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"60 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90119565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-26DOI: 10.30659/sainsmed.v13i2.27906
M. Soffan, S. Trisnadi
From 2011 to 2014, there were six cases of suspected medical malpractice in the Central Java Region; four clinical cases were resolved by an ethics board and two by a public court, so that it serves as a reference for clinical decision-making for physicians, as many ethical problems in addition to legal problems exist in medicine. Doctors, as Indonesian citizens, are obligated to implement the norms and laws that apply in Indonesia. However, as professionals, they are also obligated to implement the norms that apply in medical professional organisations (Indonesian Doctors Association/IDI), including the Indonesian Doctors Association (IDI), the Code of Medical Ethics (KODEKI), and interprofessional ethics. So that the actions of physicians can be accounted for from both a legal and an ethical standpoint of the medical profession. Every clinical case a physician encounters has inextricable ethical and medical dimensions, necessitating a prudent method for making clinical decisions. The challenge is to comprehend the value hierarchy, beginning with norms, morals, principles, standards, and rules. Therefore, when making clinical decisions, physicians are truly guided by the order of applicable values, one of which is Jonsen-4-box Siegler’s method. The culture of the Indonesian people includes a 4-box method as an alternative. Schematics can be made for the order of values and ways of making clinical decisions based on wise ethical decisions in resolving ethical dilemmas and medical disputes.
{"title":"Hierarchy of clinical decision-making by physicians based on medical and ethical decision making","authors":"M. Soffan, S. Trisnadi","doi":"10.30659/sainsmed.v13i2.27906","DOIUrl":"https://doi.org/10.30659/sainsmed.v13i2.27906","url":null,"abstract":"From 2011 to 2014, there were six cases of suspected medical malpractice in the Central Java Region; four clinical cases were resolved by an ethics board and two by a public court, so that it serves as a reference for clinical decision-making for physicians, as many ethical problems in addition to legal problems exist in medicine. Doctors, as Indonesian citizens, are obligated to implement the norms and laws that apply in Indonesia. However, as professionals, they are also obligated to implement the norms that apply in medical professional organisations (Indonesian Doctors Association/IDI), including the Indonesian Doctors Association (IDI), the Code of Medical Ethics (KODEKI), and interprofessional ethics. So that the actions of physicians can be accounted for from both a legal and an ethical standpoint of the medical profession. Every clinical case a physician encounters has inextricable ethical and medical dimensions, necessitating a prudent method for making clinical decisions. The challenge is to comprehend the value hierarchy, beginning with norms, morals, principles, standards, and rules. Therefore, when making clinical decisions, physicians are truly guided by the order of applicable values, one of which is Jonsen-4-box Siegler’s method. The culture of the Indonesian people includes a 4-box method as an alternative. Schematics can be made for the order of values and ways of making clinical decisions based on wise ethical decisions in resolving ethical dilemmas and medical disputes.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74571698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-23DOI: 10.30659/sainsmed.v13i2.20235
Wisnu Riyan Pratama Putra, Putu Oky Ari Tania, I. Njoto, Sianny Suryawati
Chronic kidney disease (CKD) is a pathological stage with multiple causes that is characterised by a very high level of urea in the body because the kidneys are unable to balance the metabolism of fluids and electrolytes. Previous research has demonstrated that high blood pressure is one of the causes of chronic kidney disease. This study was conducted to determine the relationship between blood pressure and the initial stage of chronic kidney disease. observational study of Ninety patients with chronic kidney disease (CKD) at the RSUD Dr. Soeroto, Ngawi participated in this cross-sectional. Subjects were required to have CKD stages I-IV, high blood pressure, to be hospitalised for the first time at RSUD dr Soeroto, Ngawi, and to have never been treated for hypertension. This study employed the Spearman rank test, which was analysed by SPSS (p<0.05). 64.5% of patients with chronic kidney disease have reached stage V. In contrast, 47.8% of patients with chronic kidney disease have stage 2 hypertension. The Spearman Rank test revealed a p-value of 0.000 (<0.05) between blood pressure and the stage of chronic kidney disease at the time of initial diagnosis in patients with chronic kidney disease. The correlation coefficient has a value of 0.638, making it a strong correlation. There is a strong correlation between blood pressure and the stage of chronic kidney disease at the initial diagnosis of chronic kidney disease patients at the RSUD Dr. Soeroto, Ngawi.
慢性肾脏疾病(CKD)是一种由多种原因引起的病理阶段，其特征是由于肾脏无法平衡液体和电解质的代谢，体内尿素水平非常高。先前的研究表明，高血压是导致慢性肾脏疾病的原因之一。这项研究是为了确定血压与慢性肾脏疾病初期的关系。在RSUD的90例慢性肾脏疾病(CKD)患者的观察性研究Soeroto, Ngawi博士参加了这个横断面研究。受试者被要求患有CKD I-IV期，高血压，首次在RSUD dr Soeroto, Ngawi住院，并且从未接受过高血压治疗。本研究采用Spearman秩次检验，采用SPSS统计分析(p<0.05)。64.5%的慢性肾病患者达到v期，而47.8%的慢性肾病患者有2期高血压。Spearman Rank检验显示，慢性肾病患者初诊时血压与慢性肾病分期之间的p值为0.000(<0.05)。相关系数为0.638，为强相关。在RSUD对慢性肾病患者进行初步诊断时，血压与慢性肾病的阶段有很强的相关性。
{"title":"Intense relationship of blood pressure and stadium of chronic kidney disease at early diagnosis","authors":"Wisnu Riyan Pratama Putra, Putu Oky Ari Tania, I. Njoto, Sianny Suryawati","doi":"10.30659/sainsmed.v13i2.20235","DOIUrl":"https://doi.org/10.30659/sainsmed.v13i2.20235","url":null,"abstract":"Chronic kidney disease (CKD) is a pathological stage with multiple causes that is characterised by a very high level of urea in the body because the kidneys are unable to balance the metabolism of fluids and electrolytes. Previous research has demonstrated that high blood pressure is one of the causes of chronic kidney disease. This study was conducted to determine the relationship between blood pressure and the initial stage of chronic kidney disease. observational study of Ninety patients with chronic kidney disease (CKD) at the RSUD Dr. Soeroto, Ngawi participated in this cross-sectional. Subjects were required to have CKD stages I-IV, high blood pressure, to be hospitalised for the first time at RSUD dr Soeroto, Ngawi, and to have never been treated for hypertension. This study employed the Spearman rank test, which was analysed by SPSS (p<0.05). 64.5% of patients with chronic kidney disease have reached stage V. In contrast, 47.8% of patients with chronic kidney disease have stage 2 hypertension. The Spearman Rank test revealed a p-value of 0.000 (<0.05) between blood pressure and the stage of chronic kidney disease at the time of initial diagnosis in patients with chronic kidney disease. The correlation coefficient has a value of 0.638, making it a strong correlation. There is a strong correlation between blood pressure and the stage of chronic kidney disease at the initial diagnosis of chronic kidney disease patients at the RSUD Dr. Soeroto, Ngawi.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87378971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Batara Sirait, Nining Handayani, Ayu Mulia Sundari, T. Wulandari, I. Sini, A. Polim, M. Rizal, A. Boediono
Our study aims to assess the utilization of oocyte cryopreservation (OC) in Indonesian women. Data from 122 women who had undergone OC was retrospectively analyzed from medical records. The baseline profile, clinical characteristics, and main outcomes comprising intentions for oocyte vitrification and outcomes following oocyte warming were examined. Out of 122 women who underwent OC, 49 patients returned and use their cryopreserved oocytes with a median duration of storage was two months. Arranged from the greatest to the least, participants had undergone the cycle of OC due to sperm factor [51 (41.80%)], increased embryo availability [6 (12.1%)], postponement of marriage [6 (12.1%)], social reasons [10 (8.19%)], and other reasons [8 (6.55%)]. Meanwhile, treatment due to advanced maternal age [6 (4.91%)], poor ovarian reserve [6 (4.91%)], cancer [5 (4.09%)], PCOS [2 (1.63%)], and endometriosis [2 (1.63%)] was reported among remaining subjects. Clinical pregnancy was reported in 12 (40.0%) patients constituting of each 6 (50.0%) subjects of day-3 and day-5 embryo transfer, respectively. Our study demonstrated that sperm factor, increased embryo availability, and postponement of marriage is the main reason for women undergoing OC in Indonesia.
{"title":"The Utilization of Oocyte Cryopreservation Among Indonesia Women","authors":"Batara Sirait, Nining Handayani, Ayu Mulia Sundari, T. Wulandari, I. Sini, A. Polim, M. Rizal, A. Boediono","doi":"10.33533/jpm.v16i2.5115","DOIUrl":"https://doi.org/10.33533/jpm.v16i2.5115","url":null,"abstract":"Our study aims to assess the utilization of oocyte cryopreservation (OC) in Indonesian women. Data from 122 women who had undergone OC was retrospectively analyzed from medical records. The baseline profile, clinical characteristics, and main outcomes comprising intentions for oocyte vitrification and outcomes following oocyte warming were examined. Out of 122 women who underwent OC, 49 patients returned and use their cryopreserved oocytes with a median duration of storage was two months. Arranged from the greatest to the least, participants had undergone the cycle of OC due to sperm factor [51 (41.80%)], increased embryo availability [6 (12.1%)], postponement of marriage [6 (12.1%)], social reasons [10 (8.19%)], and other reasons [8 (6.55%)]. Meanwhile, treatment due to advanced maternal age [6 (4.91%)], poor ovarian reserve [6 (4.91%)], cancer [5 (4.09%)], PCOS [2 (1.63%)], and endometriosis [2 (1.63%)] was reported among remaining subjects. Clinical pregnancy was reported in 12 (40.0%) patients constituting of each 6 (50.0%) subjects of day-3 and day-5 embryo transfer, respectively. Our study demonstrated that sperm factor, increased embryo availability, and postponement of marriage is the main reason for women undergoing OC in Indonesia. ","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48407961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dian Fahmi Utami, I. Idris, Arsyadi Arsyad, I. Yustisia, A. Aryandi, H. Cangara
Obesity is a health problem that often occurs in late adolescents and early adults. Endothelial damage that occurs in obese people can cause increased production of endothelin-1. This study compares urinary endothelin-1 levels in the obese and normal groups. It used analytical research methods with a quantitative approach to collect and measure data in numbers. The study design was cross-sectional by comparing endothelin-1 levels in normal and obese adolescent groups. This research was conducted in Makassar City from April to June 2022. The study population was obese and non-obese people in their late teens and early adulthood. The sample collection technique used in this study is a purposive sampling technique, which is a non-random sampling technique. The number of samples in the study for the Obese group was 26, while in the Normal group was 26. The analysis used the Independent Sample T Test statistical test. The results showed that the average urinary endothelin I level in the obese group was 40,930 ng/l, and in the normal group, 55,547 ng/l. Which shows a significant difference in average endothelin I levels (p<0.05) between the obese and normal groups.
{"title":"Analysis of Urinary Endothelin-I Levels in Obese Late Adolescents","authors":"Dian Fahmi Utami, I. Idris, Arsyadi Arsyad, I. Yustisia, A. Aryandi, H. Cangara","doi":"10.33533/jpm.v16i2.5192","DOIUrl":"https://doi.org/10.33533/jpm.v16i2.5192","url":null,"abstract":"Obesity is a health problem that often occurs in late adolescents and early adults. Endothelial damage that occurs in obese people can cause increased production of endothelin-1. This study compares urinary endothelin-1 levels in the obese and normal groups. It used analytical research methods with a quantitative approach to collect and measure data in numbers. The study design was cross-sectional by comparing endothelin-1 levels in normal and obese adolescent groups. This research was conducted in Makassar City from April to June 2022. The study population was obese and non-obese people in their late teens and early adulthood. The sample collection technique used in this study is a purposive sampling technique, which is a non-random sampling technique. The number of samples in the study for the Obese group was 26, while in the Normal group was 26. The analysis used the Independent Sample T Test statistical test. The results showed that the average urinary endothelin I level in the obese group was 40,930 ng/l, and in the normal group, 55,547 ng/l. Which shows a significant difference in average endothelin I levels (p<0.05) between the obese and normal groups.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45054665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-15DOI: 10.30659/sainsmed.v13i1.21022
Rakhmawati Agustina, Endang Puji Ati
Parental eating habits have a positive effect on children's nutritional health. Numerous studies have examined children's eating patterns; however, few studies have examined the association between parental eating patterns based on the dimensions of demandingness and responsiveness in children and the nutritional status of 6- to 24-month-old children. This study aimed to examine the relationship between parental dietary habits and the nutritional status of children aged 6–24 months in Manado City. The research employed a quantitative approach with a cross-sectional design in the working area of the Ranomut Health Center, which included six neighborhoods from three villages: Paal 2, Ranomut, and Perkamil. This village was chosen because it has the highest concentration of children under the age of five in the Ranomut Health Center's service area. In this study, 96 samples were selected using the method of purposive sampling based on the criteria established by the researcher. The instrument used was the validated and reliable Feeding Practices and Structure Questionnaire for Infants, followed by data analysis using the Spearman rank test. The respondents' parental eating styles were authoritarian (31.3%), permissive (27.1%), democratic (20%), and negligent (20%). The nutritional status of children under the age of five was 26% malnourished and 74% well-nourished. The Spearman rank test resulted in a p-value of 0.674. This can be attributed to other factors, such as family composition and age-inappropriate food portions.
{"title":"The influence of parental eating patterns on the nutritional status of Manado city children aged 6-24 months","authors":"Rakhmawati Agustina, Endang Puji Ati","doi":"10.30659/sainsmed.v13i1.21022","DOIUrl":"https://doi.org/10.30659/sainsmed.v13i1.21022","url":null,"abstract":"Parental eating habits have a positive effect on children's nutritional health. Numerous studies have examined children's eating patterns; however, few studies have examined the association between parental eating patterns based on the dimensions of demandingness and responsiveness in children and the nutritional status of 6- to 24-month-old children. This study aimed to examine the relationship between parental dietary habits and the nutritional status of children aged 6–24 months in Manado City. The research employed a quantitative approach with a cross-sectional design in the working area of the Ranomut Health Center, which included six neighborhoods from three villages: Paal 2, Ranomut, and Perkamil. This village was chosen because it has the highest concentration of children under the age of five in the Ranomut Health Center's service area. In this study, 96 samples were selected using the method of purposive sampling based on the criteria established by the researcher. The instrument used was the validated and reliable Feeding Practices and Structure Questionnaire for Infants, followed by data analysis using the Spearman rank test. The respondents' parental eating styles were authoritarian (31.3%), permissive (27.1%), democratic (20%), and negligent (20%). The nutritional status of children under the age of five was 26% malnourished and 74% well-nourished. The Spearman rank test resulted in a p-value of 0.674. This can be attributed to other factors, such as family composition and age-inappropriate food portions.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"99 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73372407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kartika Sari, D. P. O. Lestari, Novitasari Novitasari, Yudhi Nugraha, V. Prasasty, Septi Panca Sakti
Cervical cancer is the one of leading cause of death for women worldwide. It occurs due to infection with the human papilloma virus (HPV) which attacks the cervix in the female reproductive organs. The detecting cervical cancer method is by using pap smears and liquid based cytology (LBC) and vaccinations. However, both methods are limited in detecting cervical cancer quickly and accurately. This study aims to find potential biomarkers that will be used to quickly detect the development of cervical cancer. Large-scale studies have shown that microRNA-205 (miRNA) regulation has a very important role in various types of cancer including cervical cancer. The extraction and synthesis of cDNA from 26 preparations of cervical cancer paraffin blocks were measured by quantitative real time PCR to evaluate the expression of miRNA-205 as a biomarker of cervical cancer in cervical cancer samples. Statistical results showed that there was a significant difference in the expression of miRNA-205 which was relatively higher in cervical cancer patients (p<0.05) miRNA-205. In addition, the increased expression of miRNA-205 is associated with an increase in the severity of cervical cancer. We conclude that miRNA-205 is a potential candidate for cervical cancer molecular biomarker.
{"title":"The Relationship Between Cervical Cancer Severity and miRNA-205 Expression in Bali","authors":"Kartika Sari, D. P. O. Lestari, Novitasari Novitasari, Yudhi Nugraha, V. Prasasty, Septi Panca Sakti","doi":"10.33533/jpm.v16i2.4106","DOIUrl":"https://doi.org/10.33533/jpm.v16i2.4106","url":null,"abstract":"Cervical cancer is the one of leading cause of death for women worldwide. It occurs due to infection with the human papilloma virus (HPV) which attacks the cervix in the female reproductive organs. The detecting cervical cancer method is by using pap smears and liquid based cytology (LBC) and vaccinations. However, both methods are limited in detecting cervical cancer quickly and accurately. This study aims to find potential biomarkers that will be used to quickly detect the development of cervical cancer. Large-scale studies have shown that microRNA-205 (miRNA) regulation has a very important role in various types of cancer including cervical cancer. The extraction and synthesis of cDNA from 26 preparations of cervical cancer paraffin blocks were measured by quantitative real time PCR to evaluate the expression of miRNA-205 as a biomarker of cervical cancer in cervical cancer samples. Statistical results showed that there was a significant difference in the expression of miRNA-205 which was relatively higher in cervical cancer patients (p<0.05) miRNA-205. In addition, the increased expression of miRNA-205 is associated with an increase in the severity of cervical cancer. We conclude that miRNA-205 is a potential candidate for cervical cancer molecular biomarker.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48352035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：