Pub Date : 1995-04-07DOI: 10.1109/SBEC.1995.514445
N. Thompson, A. Puckett, S. Phillips, G. Reeves
Summary form only received as follows: Light sources used to cure dental restorative materials have improved greatly with many of them having intensities approaching 800 mW/cm/sup 2/. Because of the increased light intensity, the potential for exposing pulpal tissues to elevated temperatures is greater. The objective of this study was to measure the temperature rise associated with curing a dentin adhesive ProBond (Caulk Dentsply, Milford, DE) and a composite Z-100 (3M, St. Paul, MN) using an Optilux Model 401 light curing unit (Demetron Research Corp., Danbury, CT). The experimental set up consisted of a stainless steel mold having a diameter of 6 mm x 3 mm depth placed over a mylar strip and a type J thermocouple. The assembly was held at 37/spl deg/C. Three sets of measurements were taken in triplicate for the conditions: A) no material; B) bonding agent; C) bonding agent + 2 mm composite. Temperatures were recorded after exposure to the light for 10, 20, 30 and 40 seconds and are given in a table. The temperature increase was significant for each group. The largest temperature increase was 42.5/spl deg/C when no material was present. Placement of the bonding agent gave a maximum temperature increase of 31.6/spl deg/C while curing of the composite gave only a 9.5/spl deg/C increase due to its ability to act as an insulator. These results suggest that curing of bonding agents in deep restorations may expose the dentin surface to significant temperature increases even though the light source may be 3 mm from the exposed surface.
仅收到的摘要如下:用于修复牙齿修复材料的光源有了很大的改进，其中许多光源的强度接近800 mW/cm/sup /。由于光照强度的增加，使牙髓组织暴露在高温下的可能性更大。本研究的目的是测量牙本质粘合剂ProBond (Caulk Dentsply, Milford, DE)和复合材料Z-100 (3M, St. Paul, MN)使用Optilux Model 401光固化装置(Demetron Research Corp.， Danbury, CT)固化时的温升。实验装置由一个直径为6毫米x 3毫米的不锈钢模具和一个J型热电偶组成。大会在摄氏37度的温度下举行。在以下条件下进行三组测量:A)无材料;B)粘结剂;C)粘结剂+ 2mm复合材料。在光下暴露10、20、30和40秒后记录温度，并以表格形式给出。各组体温升高均显著。无材料存在时，升温幅度最大，为42.5℃/spl℃。结合剂的放置使复合材料的温度最高升高了31.6/spl℃，而由于其作为绝缘体的能力，固化后的复合材料的温度仅升高了9.5/spl℃。这些结果表明，在深度修复体中，即使光源可能距离暴露表面3mm，固结剂的固化也会使牙本质表面暴露于显著的温度升高。
{"title":"Potential hazards associated with photocuring dentin bonding agents","authors":"N. Thompson, A. Puckett, S. Phillips, G. Reeves","doi":"10.1109/SBEC.1995.514445","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514445","url":null,"abstract":"Summary form only received as follows: Light sources used to cure dental restorative materials have improved greatly with many of them having intensities approaching 800 mW/cm/sup 2/. Because of the increased light intensity, the potential for exposing pulpal tissues to elevated temperatures is greater. The objective of this study was to measure the temperature rise associated with curing a dentin adhesive ProBond (Caulk Dentsply, Milford, DE) and a composite Z-100 (3M, St. Paul, MN) using an Optilux Model 401 light curing unit (Demetron Research Corp., Danbury, CT). The experimental set up consisted of a stainless steel mold having a diameter of 6 mm x 3 mm depth placed over a mylar strip and a type J thermocouple. The assembly was held at 37/spl deg/C. Three sets of measurements were taken in triplicate for the conditions: A) no material; B) bonding agent; C) bonding agent + 2 mm composite. Temperatures were recorded after exposure to the light for 10, 20, 30 and 40 seconds and are given in a table. The temperature increase was significant for each group. The largest temperature increase was 42.5/spl deg/C when no material was present. Placement of the bonding agent gave a maximum temperature increase of 31.6/spl deg/C while curing of the composite gave only a 9.5/spl deg/C increase due to its ability to act as an insulator. These results suggest that curing of bonding agents in deep restorations may expose the dentin surface to significant temperature increases even though the light source may be 3 mm from the exposed surface.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124247701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-04-07DOI: 10.1109/SBEC.1995.514434
D. Kilpadi, G. N. Raikar, R. Connatser, J. Liu, J. Lemons, J. Gregory, Y. Vohra
The effects of surface treatment procedures as recommended by the American Society for Testing and Materials on the surface of unalloyed titanium implants were examined. Solid surface tension assessment suggested that the two-liquid Zisman plots were not sensitive to polar components and resulted in trends different from the two-liquid Kaelble plots. Raman studies did not show any crystalline order and X-ray photoelectron spectroscopy results indicated that the surface layers were composed primarily of a TiO/sub 2/ type stoichiometry along with 3 hydrocarbon overlayer. The surfaces also contained varying, although minute, amounts of surface contamination.
{"title":"Evaluation of unalloyed titanium implant surfaces","authors":"D. Kilpadi, G. N. Raikar, R. Connatser, J. Liu, J. Lemons, J. Gregory, Y. Vohra","doi":"10.1109/SBEC.1995.514434","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514434","url":null,"abstract":"The effects of surface treatment procedures as recommended by the American Society for Testing and Materials on the surface of unalloyed titanium implants were examined. Solid surface tension assessment suggested that the two-liquid Zisman plots were not sensitive to polar components and resulted in trends different from the two-liquid Kaelble plots. Raman studies did not show any crystalline order and X-ray photoelectron spectroscopy results indicated that the surface layers were composed primarily of a TiO/sub 2/ type stoichiometry along with 3 hydrocarbon overlayer. The surfaces also contained varying, although minute, amounts of surface contamination.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"539 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124530304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-04-07DOI: 10.1109/SBEC.1995.514474
Bai-lian Li, Hsin-i Wu
Wavelet analysis is a recently developed mathematical theory and computational method for decomposing a nonstationary signal into components that have good localization properties both in time and frequency and hierarchical structures. Wavelet transform provides local information and multiresolution decomposition on a signal that cannot be obtained using traditional methods such as Fourier transforms and statistical estimation theory. Hence the change in complex biological signals can be detected. We use wavelet analysis as an innovative method for identifying and characterizing chaotic biological signals in this paper. We usually do not know the underlying mechanism that determine the behavior of a biosystem. We are instead presented with nothing more than a phenomenological time series signal of the behavior, and must infer the mechanism from simple measurements of that time series. Data we used are simulated chaotic signals from the logistic equation. Using wavelet transformation we extract instantaneous frequencies of the signal varying in time across scales. The results under different parameters and initial conditions show that the phase maps of their wavelet transforms are different between period doubling bifurcation and chaos. This information could be used as a diagnostic for detecting different nonlinear dynamic responses. This may lead to a better understanding of the system, that may allow us to predict the onset of lethal arrhythmias and to intervene prior to the development of catastrophic clinical events.
{"title":"Wavelet transformation of chaotic biological signals","authors":"Bai-lian Li, Hsin-i Wu","doi":"10.1109/SBEC.1995.514474","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514474","url":null,"abstract":"Wavelet analysis is a recently developed mathematical theory and computational method for decomposing a nonstationary signal into components that have good localization properties both in time and frequency and hierarchical structures. Wavelet transform provides local information and multiresolution decomposition on a signal that cannot be obtained using traditional methods such as Fourier transforms and statistical estimation theory. Hence the change in complex biological signals can be detected. We use wavelet analysis as an innovative method for identifying and characterizing chaotic biological signals in this paper. We usually do not know the underlying mechanism that determine the behavior of a biosystem. We are instead presented with nothing more than a phenomenological time series signal of the behavior, and must infer the mechanism from simple measurements of that time series. Data we used are simulated chaotic signals from the logistic equation. Using wavelet transformation we extract instantaneous frequencies of the signal varying in time across scales. The results under different parameters and initial conditions show that the phase maps of their wavelet transforms are different between period doubling bifurcation and chaos. This information could be used as a diagnostic for detecting different nonlinear dynamic responses. This may lead to a better understanding of the system, that may allow us to predict the onset of lethal arrhythmias and to intervene prior to the development of catastrophic clinical events.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124938736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-04-07DOI: 10.1109/SBEC.1995.514475
C. Yin, R. Woledge
Traditionally, muscle efficiency studies were performed on frog muscles. Muscles of other animal species are assumed to have efficiency values similar to that in frog muscles. This assumption has not been vigorously tested. Our goal was to test this assumption by determining efficiencies of mouse and frog muscles and comparing them. Mouse soleus and frog semitendinosus muscles were isolated and stimulated electrically to produce shortening against external load. The force, muscle length and temperature change associated with these contractions were recorded simultaneously. Efficiency values were worked out from these signals. Our results showed that mouse soleus muscle had a significantly lower efficiency than frog semitendinosus.
{"title":"Efficiency of muscular contractions in mouse is different from that in frog","authors":"C. Yin, R. Woledge","doi":"10.1109/SBEC.1995.514475","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514475","url":null,"abstract":"Traditionally, muscle efficiency studies were performed on frog muscles. Muscles of other animal species are assumed to have efficiency values similar to that in frog muscles. This assumption has not been vigorously tested. Our goal was to test this assumption by determining efficiencies of mouse and frog muscles and comparing them. Mouse soleus and frog semitendinosus muscles were isolated and stimulated electrically to produce shortening against external load. The force, muscle length and temperature change associated with these contractions were recorded simultaneously. Efficiency values were worked out from these signals. Our results showed that mouse soleus muscle had a significantly lower efficiency than frog semitendinosus.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123713620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-04-07DOI: 10.1109/SBEC.1995.514463
R. Misra
Scleral buckling or indentation over a retinal tear or detachment was popularized by Ernst Custodis in 1953. Since then it has become one of the most popular and effective retinal reattachment surgical procedures. Although a few biologic materials such as fascia lata, lyophilized sclera and gelatin are used sometimes as scleral buckles, the most common material for buckles currently used is derivatives of medical grade silicone rubber or MAI. When the scleral buckling material is of foreign origin, the body reacts with acute and chronic inflammation, extrusion, and intrusion. The author has studied five eneucleated globes, with scleral buckles in place for periods of 3 to 48 months. The globes were removed for "painful blind eyes". The author's studies consisted of histomorphological analyses. The author observed foreign body granulomatous reaction and extensive fibrosis of Tenon's capsule and the sclera. The precise mechanism by which scleral buckling works remain uncertain at this time.
{"title":"Pathologic processes associated with the use of scleral buckling in humans","authors":"R. Misra","doi":"10.1109/SBEC.1995.514463","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514463","url":null,"abstract":"Scleral buckling or indentation over a retinal tear or detachment was popularized by Ernst Custodis in 1953. Since then it has become one of the most popular and effective retinal reattachment surgical procedures. Although a few biologic materials such as fascia lata, lyophilized sclera and gelatin are used sometimes as scleral buckles, the most common material for buckles currently used is derivatives of medical grade silicone rubber or MAI. When the scleral buckling material is of foreign origin, the body reacts with acute and chronic inflammation, extrusion, and intrusion. The author has studied five eneucleated globes, with scleral buckles in place for periods of 3 to 48 months. The globes were removed for \"painful blind eyes\". The author's studies consisted of histomorphological analyses. The author observed foreign body granulomatous reaction and extensive fibrosis of Tenon's capsule and the sclera. The precise mechanism by which scleral buckling works remain uncertain at this time.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125424546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-04-07DOI: 10.1109/SBEC.1995.514439
B. Bennett, A. Puckett, J. Fitchie
Summary form only given. The objective of this study was to evaluate the change in Barcol hardness of five different hybrid glass ionomers (GI) after storage in distilled H/sub 2/O at 37/spl deg/C. The materials were (A) Encapsulated and (B) Handmixed Variglass (Caulk Dentsply, Milford, DE), (C) Vitremer (3M, St. Paul, MN), (D) Fuji II (GC Corp., Tokyo, Japan) and (E) Photacfil (ESPE Premier, Norristown, PA). Barcol hardness measurements were taken on all the samples after twenty-four hours, 1 week and 1 month of aging. Comparison of the initial hardness using ANOVA (p<0.05) revealed no significant differences. However, materials A and B showed a decrease in hardness after 1 week of storage. In contrast, materials C, D and E showed a significant increase (p<0.05) in hardness after storage. Based upon these results, it may be concluded that materials C, D and E continue to react during aging resulting in a harder material. In contrast, the materials A and B do not continue to react but actually become softer due to plasticization by absorbed water. The additional reaction of materials C, D and E is most probably the result of further ionic crosslinking which may be facilitated by water absorption.
只提供摘要形式。本研究的目的是评价5种不同的杂化玻璃离子(GI)在37℃/spl℃的蒸馏H/sub /O中保存后的硬度变化。材料为(A)封装和(B)手工混合varigglass (Caulk Dentsply, Milford, DE)， (C) Vitremer (3M, St. Paul, MN)， (D) Fuji II (GC Corp, Tokyo, Japan)和(E) Photacfil (ESPE Premier, Norristown, PA)。分别在时效24小时、1周和1个月后对样品进行巴氏硬度测定。采用方差分析比较初始硬度(p<0.05)，差异无统计学意义。然而，材料A和材料B在储存1周后硬度下降。C、D、E材料贮藏后硬度显著升高(p<0.05)。根据这些结果，可以得出结论，材料C、D和E在时效过程中继续发生反应，导致材料变硬。相反，材料A和材料B不会继续反应，而是由于吸收的水的塑化而变得更软。材料C、D和E的附加反应很可能是进一步离子交联的结果，而离子交联可以通过吸水来促进。
{"title":"Aging characteristics of four hybrid glass ionomers","authors":"B. Bennett, A. Puckett, J. Fitchie","doi":"10.1109/SBEC.1995.514439","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514439","url":null,"abstract":"Summary form only given. The objective of this study was to evaluate the change in Barcol hardness of five different hybrid glass ionomers (GI) after storage in distilled H/sub 2/O at 37/spl deg/C. The materials were (A) Encapsulated and (B) Handmixed Variglass (Caulk Dentsply, Milford, DE), (C) Vitremer (3M, St. Paul, MN), (D) Fuji II (GC Corp., Tokyo, Japan) and (E) Photacfil (ESPE Premier, Norristown, PA). Barcol hardness measurements were taken on all the samples after twenty-four hours, 1 week and 1 month of aging. Comparison of the initial hardness using ANOVA (p<0.05) revealed no significant differences. However, materials A and B showed a decrease in hardness after 1 week of storage. In contrast, materials C, D and E showed a significant increase (p<0.05) in hardness after storage. Based upon these results, it may be concluded that materials C, D and E continue to react during aging resulting in a harder material. In contrast, the materials A and B do not continue to react but actually become softer due to plasticization by absorbed water. The additional reaction of materials C, D and E is most probably the result of further ionic crosslinking which may be facilitated by water absorption.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129400461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-04-07DOI: 10.1109/SBEC.1995.514491
S. Panteliou, H. Abbasi-Jahromi, A. Dimarogonas
A non-invasive method to measure bone integrity has been developed which has potential for monitoring osteoporosis. It is based on a patented process of obtaining the dynamic characteristics of the bone using dynamic excitation in the range of acoustic frequencies (a sound source). The Modal Damping Factor has been used as an indicator of the tendency of the bone to fracture. Results of numerous animal studies have supported this hypothesis.
{"title":"The acoustic sweep method for monitoring osteoporosis","authors":"S. Panteliou, H. Abbasi-Jahromi, A. Dimarogonas","doi":"10.1109/SBEC.1995.514491","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514491","url":null,"abstract":"A non-invasive method to measure bone integrity has been developed which has potential for monitoring osteoporosis. It is based on a patented process of obtaining the dynamic characteristics of the bone using dynamic excitation in the range of acoustic frequencies (a sound source). The Modal Damping Factor has been used as an indicator of the tendency of the bone to fracture. Results of numerous animal studies have supported this hypothesis.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117057341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-04-07DOI: 10.1109/SBEC.1995.514417
Qian Tan, S. Napper
Summary form only given. The progressive withdrawal of mechanical ventilation is called weaning. A computerized decision support system (off-line or on-line) would help the medical staff to wean patients more efficiently and can potentially reduce treatment duration and mortality rates. The aim of this research is to design a model-based reasoning system to provide on-line guidance in respiratory weaning process management. In this approach, the semi-quantitative reasoning method is applied to regulate and control the weaning process by adjusting the ventilator settings. A semi-quantitative method provides a level of description that is intermediate between abstract qualitative models and precise numerical models. It combines both qualitative and quantitative knowledge within a single semi-quantitative qualitative differential equation (SQDE) representation. It is a set of qualitative constraints which are augmented with envelopes for all monotonic functions and numeric ranges for all model variables and initial conditions. The model is then simulated to compute the variables in ventilator setting. The control system is tested under different physiological conditions, using a detailed simulation model of the human respiratory system.
{"title":"A model-based reasoning system for the management of respiratory weaning process","authors":"Qian Tan, S. Napper","doi":"10.1109/SBEC.1995.514417","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514417","url":null,"abstract":"Summary form only given. The progressive withdrawal of mechanical ventilation is called weaning. A computerized decision support system (off-line or on-line) would help the medical staff to wean patients more efficiently and can potentially reduce treatment duration and mortality rates. The aim of this research is to design a model-based reasoning system to provide on-line guidance in respiratory weaning process management. In this approach, the semi-quantitative reasoning method is applied to regulate and control the weaning process by adjusting the ventilator settings. A semi-quantitative method provides a level of description that is intermediate between abstract qualitative models and precise numerical models. It combines both qualitative and quantitative knowledge within a single semi-quantitative qualitative differential equation (SQDE) representation. It is a set of qualitative constraints which are augmented with envelopes for all monotonic functions and numeric ranges for all model variables and initial conditions. The model is then simulated to compute the variables in ventilator setting. The control system is tested under different physiological conditions, using a detailed simulation model of the human respiratory system.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123866973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-04-07DOI: 10.1109/SBEC.1995.514501
T. Tateishi, T. Ushida
The aim of this study is to measure adhesion strength of cultured cells to bioceramics such as alumina, and to adapt a mathematical model of defect growth kinetics to the cell adhesion phenomena. Fibroblasts from mouse (L-929) were cultured on alumina plates and fibronectin-coated alumina plates. The adhesion strength was measured by loading adhered cells with centrifugal force vertical to the material's surface. At the same time, we measured adhered areas and morphology of cells on the 2 types of surfaces by using an image analyzing method. The results show that the cells adhered more tightly to fibronectin coated alumina than to alumina. (50% of the cells were peeled off from the fibronectin-coated alumina under the load of 500 G, while 50% of the cells were peeled off from the alumina under the load of 100 G.) The image processed data show that the average of adhered areas of cells to fibronectin coated alumina was 3 times as large as to alumina 6 hours after seeding. The results show influence of fibronectin-receptor bonds on the cell's adhesion strength and the cell's adhesion phenomena. Considering the influence of fibronectin-receptor bonds, a mathematical model of defect growth kinetics was adapted to the cells adhesion phenomena, where we assumed that the rate of condensation of vacancies or the rate of rupture of fibronectin-receptor bonds at the tip of the crack was proportional to the radius of the crack.
{"title":"Cell adhesion strength to bioceramics and morphology","authors":"T. Tateishi, T. Ushida","doi":"10.1109/SBEC.1995.514501","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514501","url":null,"abstract":"The aim of this study is to measure adhesion strength of cultured cells to bioceramics such as alumina, and to adapt a mathematical model of defect growth kinetics to the cell adhesion phenomena. Fibroblasts from mouse (L-929) were cultured on alumina plates and fibronectin-coated alumina plates. The adhesion strength was measured by loading adhered cells with centrifugal force vertical to the material's surface. At the same time, we measured adhered areas and morphology of cells on the 2 types of surfaces by using an image analyzing method. The results show that the cells adhered more tightly to fibronectin coated alumina than to alumina. (50% of the cells were peeled off from the fibronectin-coated alumina under the load of 500 G, while 50% of the cells were peeled off from the alumina under the load of 100 G.) The image processed data show that the average of adhered areas of cells to fibronectin coated alumina was 3 times as large as to alumina 6 hours after seeding. The results show influence of fibronectin-receptor bonds on the cell's adhesion strength and the cell's adhesion phenomena. Considering the influence of fibronectin-receptor bonds, a mathematical model of defect growth kinetics was adapted to the cells adhesion phenomena, where we assumed that the rate of condensation of vacancies or the rate of rupture of fibronectin-receptor bonds at the tip of the crack was proportional to the radius of the crack.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126280255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-04-07DOI: 10.1109/SBEC.1995.514459
S. Saha
Health care management costs rise yearly, especially in the areas of personnel and the expenses of generating and maintaining the patients' records. A substantial informational burden is incurred with each patient visit to a health professional, and patients' needs are often lost in the shuffle of medical records, insurance information, and red tape. However during the last few years significant progress has been made in the development of clinically useful medical decision support system to assist the health care provider. Earlier efforts to implement computer-based patient records mainly used keyboard entry, but with the latest technology, voice activated clinical reporting systems could be a central component of such a computer-based system in the future. Several groups are in the process of developing portable data management device. This will allow the clinicians to have on-line readily transferable patient records, decision making support and searching of remote databases to better analyze complex health care delivery problems. When the medical transcriptions are forwarded to an off-site location, this unique device will reduce the time and the cost of re-recording and transmission. This device will help the user to maintain and update the data remotely and instantly. It will also provide immediate information updates and database manipulations for all aspects of medical data management, provide portable multiple and simultaneous access to complete database information. These will significantly reduce paperwork and personnel costs.
{"title":"The new age electronic patient record system","authors":"S. Saha","doi":"10.1109/SBEC.1995.514459","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514459","url":null,"abstract":"Health care management costs rise yearly, especially in the areas of personnel and the expenses of generating and maintaining the patients' records. A substantial informational burden is incurred with each patient visit to a health professional, and patients' needs are often lost in the shuffle of medical records, insurance information, and red tape. However during the last few years significant progress has been made in the development of clinically useful medical decision support system to assist the health care provider. Earlier efforts to implement computer-based patient records mainly used keyboard entry, but with the latest technology, voice activated clinical reporting systems could be a central component of such a computer-based system in the future. Several groups are in the process of developing portable data management device. This will allow the clinicians to have on-line readily transferable patient records, decision making support and searching of remote databases to better analyze complex health care delivery problems. When the medical transcriptions are forwarded to an off-site location, this unique device will reduce the time and the cost of re-recording and transmission. This device will help the user to maintain and update the data remotely and instantly. It will also provide immediate information updates and database manipulations for all aspects of medical data management, provide portable multiple and simultaneous access to complete database information. These will significantly reduce paperwork and personnel costs.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131240396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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