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DENGUE: WHO IS DYING IN THE STATE OF PARÁ? 登革热:谁在parÁ州死亡?
Q4 Medicine Pub Date : 2018-12-27 DOI: 10.28951/RBB.V36I4.320
Jose Lisboa, C. Souza, E. M. Ramos, Silvia dos Santos de Almeida
In the last 50 years, the incidence of dengue grew over 30 times, with the development of the geographical expansion for new countries and currently, reaching small towns and rural areas. It is estimated about over than 50 million of infection by dengue occur annually and approximately 2.5 billion people die in countries where the disease is endemic. In the state of Pará, 4042 cases of dengue were confirmed until October 1st, 2015. At the same period in the year of 2014, 2704 occurrences were registered, which represents an increase of almost 50%. Thus, this work’s objective is to trace the patient’s with dengue profiles in the state of Pará and to verify the relationship between those patients stage of life  and the type of dengue with evolution case. For this end, the descriptive analysis technique was utilized, aiming to trace the patient’s profiles confirmed with dengue. The correspondence analysis technique was utilized to verify what was (exclude) the relationship between the patients’s stage of life and the type of dengue fever with evolution case. As the main results, it was noticed that the majority of the patients are female, residing in urban zones and are adults. It was still perceived that elders, children and individuals that had dengue with complications, shock syndrome and hemorrhagic fever had the highest probabilities  of dying. Therefore, it is due noticed that is important to give this disease greater attention,  above all to the children and elderly stages of life, because, from the results it was evidenced that the individuals on these stages of life are the most prone to die from the disease. 
在过去50年里,登革热的发病率增长了30多倍,随着新国家的地理扩展发展,目前已到达小城镇和农村地区。据估计,在登革热流行的国家,每年约有5 000多万人感染登革热,约有25亿人死亡。截至2015年10月1日,帕尔州共确诊登革热病例4042例。2014年同期,共发生2704起,增长了近50%。因此,这项工作的目的是追踪病人的登革热概况在par状态,并验证这些病人的生命阶段和登革热类型与进化病例之间的关系。为此,利用描述性分析技术,旨在追踪确诊为登革热的患者资料。利用对应分析技术验证(排除)进化病例患者的生命阶段与登革热类型之间的关系。主要结果是,大多数患者是女性,居住在城市地区,是成年人。人们仍然认为,老年人、儿童和患有登革热并伴有并发症、休克综合征和出血热的个人死亡的可能性最高。因此,应当注意到,必须对这种疾病给予更多的关注,首先是儿童和老年阶段,因为从结果来看,处于这些生命阶段的人最容易死于这种疾病。
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引用次数: 0
THE PERFORMANCE OF AFFIRMATIVE ACTION STUDENTS AND ANALYSIS OF SUBJECTS GRADES USING LATENT CLASS AND LATENT BUDGET MODELS 平权行动学生的表现及使用潜在阶级和潜在预算模型的学科成绩分析
Q4 Medicine Pub Date : 2018-12-27 DOI: 10.28951/RBB.V36I4.309
E. Jelihovschi
Latent class analysis (LCA) is used to analyse data about performance of students. The original performance variables in the data set are course grade and approval status. However, those variables were not used directly, instead four new variables were calculated from those previous two, variables which are much more informative about the student performance. Coupled with another variable, say afirmative action, the results give light to an understanding about the performance of the divided by afirmative action, yes or no. Besides of showing the results it is also shown how the changing of the original variables by some suitable transformation of the original ones gives more reliable results. The main result is that armative action students have a lower performance than those coming from private schools. The paper also analyses the subjects grades using latent budget analysis (LBA), and it is found that the variables cited above have a real effect in characterizing the subjects. It is also shown that those results can be used in a process of evaluation on how the subject is being taught.
潜类分析(LCA)用于分析学生的表现数据。数据集中的原始绩效变量为课程成绩和审批状态。然而,这些变量并不是直接使用的,而是从之前的两个变量中计算出四个新的变量,这些变量对学生的表现有更多的信息。再加上另一个变量,比如平权行动,结果让我们了解了平权行动对学生表现的影响,是或否。除了给出结果外,还说明了如何通过对原始变量进行适当的变换来改变原始变量,从而得到更可靠的结果。主要结果是,私立学校的学生比私立学校的学生表现更差。本文还利用潜在预算分析(latent budget analysis, LBA)对被试的成绩进行了分析,发现上述变量对被试的特征具有真实的影响。研究还表明,这些结果可以用于评估该学科的教学情况。
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引用次数: 0
THE BETA EXPONENTIATED WEIBULL GEOMETRIC DISTRIBUTION: MODELING, STRUCTURAL PROPERTIES, ESTIMATION AND AN APPLICATION TO A CERVICAL INTRAEPITHELIAL NEOPLASIA DATASET β指数威布尔几何分布:建模,结构特性,估计和应用于宫颈上皮内瘤变数据集
Q4 Medicine Pub Date : 2018-12-27 DOI: 10.28951/RBB.V36I4.329
F. Louzada, I. Elbatal, D. Granzotto
A new distribution, the so called beta exponentiated Weibull geometric (BEWG) distribution is proposed. The new distribution is generated from the logit of a beta random variable and includes the exponentiated Weibull geometric distribution as particular case. Various structural properties including explicit expressions for the moments, moment generating function, mean deviation of the new distribution are derived. The estimation of the model parameters is performed by maximum likelihood method. The usefulness of the model was showed by using a real dataset. In order to validate the results a simulation bootstrap is presented in this paper.
提出了一种新的分布,即指数威布尔几何分布。该新分布由随机变量的logit生成,并将指数威布尔几何分布作为特殊情况。推导了各种结构性质,包括矩的显式表达式、矩生成函数、新分布的平均偏差。采用极大似然法对模型参数进行估计。通过实际数据集验证了该模型的有效性。为了验证结果,本文给出了一个仿真自举。
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引用次数: 1
GOMPERTZ REGRESSION MODEL WITH GAMMA FRAILTY: A STUDY ON THE APPLICATION IN LUNG CANCER 具有γ脆弱的Gompertz回归模型在肺癌中的应用研究
Q4 Medicine Pub Date : 2018-12-27 DOI: 10.28951/RBB.V36I4.312
V. Tomazella, E. Milani, Teresa C. M. Dias
Survival models with frailty are used when some variables are non-available to explain the occurrence time of an event of interest. This non-availability may be considered as a random effect related to unobserved covariates, or that cannot be measured, such as environmental or genetic factors. This paper focuses on the Gamma-Gompertz (denoted by G-G) model that is one of a class of models that investigate the effects of unobservable heterogeneity. We assume that the baseline mortality rate in the G-G model is the Gompertz model, in which mortality increases exponentially with age and the frailty is a fixed property of the individual, and the distribution of frailty is a gamma distribution. The proposed methodology uses the Laplace transform to find the unconditional survival function in the individual frailty. Estimation is based on maximum likelihood methods and this distribution is compared with its particular case. A simulation study examines the bias, the mean squared errors and the coverage probabilities considering various samples sizes and censored data. A real example with lung cancer data illustrates the applicability of the methodology, where we compared the G-G and without frailty models via criteria which select thebest fitted model to the data. 
当某些变量无法解释感兴趣的事件的发生时间时,使用带有脆弱性的生存模型。这种不可获得性可能被认为是与未观察到的协变量相关的随机效应,或者是无法测量的随机效应,例如环境或遗传因素。本文关注的是Gamma-Gompertz(用G-G表示)模型,它是一类研究不可观测异质性影响的模型之一。我们假设G-G模型中的基线死亡率为Gompertz模型,其中死亡率随年龄呈指数增长,脆弱性是个体的固定属性,脆弱性的分布为gamma分布。该方法利用拉普拉斯变换求个体脆弱状态下的无条件生存函数。估计是基于极大似然方法,并将这种分布与它的特殊情况进行比较。模拟研究考察了考虑不同样本量和截尾数据的偏差、均方误差和覆盖概率。肺癌数据的一个真实例子说明了该方法的适用性,我们通过选择最适合数据的模型的标准来比较G-G和无脆弱性模型。
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引用次数: 1
THE THEORY OF THE INTERNALLY STUDENTIZED RANGE DISTRIBUTION REVISITED 重新审视了内部研究的范围分布理论
Q4 Medicine Pub Date : 2018-12-27 DOI: 10.28951/RBB.V36I4.308
D. F. Ferreira, L. Chaves, Devanil Jaques de Souza
The present paper intends to revisit the distribution of the ratio of the range to the sample standard deviation, known as the distribution of the internally studentized range, in the normal case. This distribution has its importance recognized in several areas, as quality control and inference, for testing the lack of homogeneity of the data or kurtosis. An alternative distribution to the one presented by David et al. (1954), based on the distribution of the maximum, is proposed. We exhibit a detailed proof for the distribution of the internally studentized range in the normal case and sample size 3. We also provide a new result: the distribution for the uniform case with sample of size 3.
本文打算重新审视在正常情况下,范围与样本标准差之比的分布,即内部研究范围的分布。这种分布的重要性在几个领域得到了认可,如质量控制和推理,用于测试数据的缺乏同质性或峰度。David et al.(1954)提出了一种基于最大值分布的替代分布。我们展示了在正常情况和样本容量3下内部研究范围分布的详细证明。我们还提供了一个新的结果:样本大小为3的均匀情况下的分布。
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引用次数: 0
LONGITUDINAL DATA ANALYSIS OF STEVIA REBAUDIANA EVAPOTRANSPIRATION ACCORDING TO WATER LEVELS 甜叶菊随水位变化蒸散量的纵向数据分析
Q4 Medicine Pub Date : 2018-12-27 DOI: 10.28951/RBB.V36I4.306
O. C. N. Pereira, P. V. C. Pereira, Altair Bertonha, I. Previdelli
The purpose of this work was to evaluate the accumulated evapotranspiration of stevia, planted in 40 pots, over a period of 27 days according to four irrigation levels through a nonlinear mixed eects model and, with this model, to verify if we can maximize the stevia's evapotranspiration with a lower than usual water level. When the humidity of the substrate reached 50% of its maximum capacity retention, we added water to raise the humidity according to the four treatments: W1 = 62:5%; W2 = 75:0%; W3 = 87:5%; W4 = 100:0%. Although the crop production depends on the availability of water in the soil, there is a limit for the total yield. The water levels, W3 and W4, resulted in similar total accumulated evapotranspiration, while all the last three water levels, W2, W3 and W4 had close shoot dry matter masses at the end of the experiment. We showed that is possible to nd an optimal level of crop production with a rational use of the available water resources. 
本研究的目的是通过非线性混合效应模型,评估40盆甜叶菊在27天内根据4种灌溉水平的累积蒸散量,并利用该模型验证是否可以在低于正常水位的情况下最大化甜叶菊的蒸散量。当基质湿度达到其最大容量保留量的50%时,按W1 = 62:5%四种处理方式加水提高湿度;W2 = 75:0%;W3 = 87:5%;W4 = 100%:0%。虽然作物产量取决于土壤中水分的可用性,但总产量是有限制的。W3、W4三个水位的总累积蒸散量相近,W2、W3、W4三个水位在试验结束时的地上部干物质质量接近。我们表明,通过合理利用现有水资源,可以找到最佳的作物生产水平。
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引用次数: 2
ARTIFICIAL NEURAL NETWORKS FOR MODELING HYPSOMETRIC RELATIONSHIPS OF Pinus caribaea Morelet var. caribaea Barr. & Golf. 基于人工神经网络的东北松林拟合关系建模。和高尔夫球。
Q4 Medicine Pub Date : 2018-12-27 DOI: 10.28951/RBB.V36I4.315
O. G. M. Guera, José Antônio Aleixo da Silva, R. Ferreira, H. B. Medel, D. Lazo
The present study was carried out to compare the performances of regression models and Artificial Neural  Networks (ANNs) in hypsometric relationships modeling and to analyze the influence of ANN type  and sample size on ANN performance. The database was consisted by 65 circular plots of 500 m² in which  Diameter at Breast Height - DBH (cm) and Total Height - Ht (m) of 2538 trees were measured in plantations of Pinus caribaea var. caribaea in Macurije forest company, Cuba. The study was carried out in three  stages: i) Fit of traditional hypsometric models and sigmoidal growth models; ii) ANNs training and comparison of the selected ANN with the regression model selected; iii) Analysis of sample size and ANN type influences on the estimates precision by means of a completely random experimental design with 5x2 factorial arrangement, with the factors sample size (N) and ANN type (R). The results indicated that the best equation to estimate trees heights was that of Gompertz. The ANNs MLP 1-4-1 and MLP 8-4-1 were superior to the selected equation (Gompertz). Multi-Layer Perceptron ANNs generated more accurate estimates and their performances were less influenced by the sample size.
本研究比较了回归模型和人工神经网络(ANN)在拟合关系建模中的性能,并分析了ANN类型和样本量对ANN性能的影响。该数据库由65个500 m²的圆形样地组成,其中测量了古巴Macurije森林公司加勒比松(Pinus caribaea var. caribaea)人工林2538棵树的胸径- DBH (cm)和总高度- Ht (m)。研究分三个阶段进行:i)传统的拟合模型与s型增长模型的拟合;ii)对人工神经网络进行训练,并将所选人工神经网络与所选回归模型进行比较;iii)采用5 × 2全随机试验设计,以样本量(N)和人工神经网络类型(R)为因子,分析样本量和人工神经网络类型对树高估计精度的影响。结果表明,估算树高的最佳方程为Gompertz方程。人工神经网络MLP 1-4-1和MLP 8- 1- 1优于所选方程(Gompertz)。多层感知器人工神经网络产生了更准确的估计,其性能受样本量的影响较小。
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引用次数: 1
THE USE OF CONTRASTS IN MULTIVARIATE NONLINEAR MIXED MODELS TO COMPARE TREATMENTS IN LONGITUDINAL FACTORIAL EXPERIMENTS 在多变量非线性混合模型中使用对比来比较纵向因子实验中的处理
Q4 Medicine Pub Date : 2018-12-27 DOI: 10.28951/RBB.V36I4.314
L. Carvalho, M. Mischan, J. R. S. Passos, S. Z. D. Pinho
The purpose of this study was to establish contrasts in multivariate nonlinear mixed models to verify the effects of treatments in experiments with longitudinal data and multiple responses. The evaluated nonlinear functions were the three parameters curves logistic, Gompertz and von Bertalanffy. The random variables were added to the fixed parameters, asymptote α , abscissa of the inflection point  β, and parameter γ. The best fitted model was expanded with covariates, which establish orthogonal contrasts, in order to verify main effects and interactions in factorial experiments. The methodology was applied to analyse data of an experiment with citrus, in which case the logistic bivariate mixed effects model was the best fit. The chosen model allowed comparisons between treatments in a global context of more than one dependent variable and throughout the measurement period. 
本研究的目的是建立多元非线性混合模型的对比,在纵向数据和多响应的实验中验证处理的效果。评估的非线性函数为logistic、Gompertz和von Bertalanffy三参数曲线。将随机变量加入固定参数、渐近线α、拐点横坐标β和参数γ中。用协变量对拟合最佳的模型进行扩展,建立正交对比,以验证析因实验中的主效应和相互作用。将该方法应用于柑橘试验数据分析,logistic双变量混合效应模型最适合。所选择的模型允许在多个因变量的全球背景下和整个测量期间对治疗进行比较。
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引用次数: 0
Aplicação da metodologia Peaks Over Threshold ao Salto em Comprimento do Atletismo “峰值超过阈值”方法在田径跳远中的应用
Q4 Medicine Pub Date : 2018-12-01 DOI: 10.28951/RBB.V36I4
D. Silva, F. Caeiro, M. M. Oliveira
 RESUMO: O método Peaks Over Threshold (POT) consiste no ajuste da distribuição generalizada de Pareto aos excessos aleatórios independentes e identicamente distribuídos acima de um limiar elevado. Neste estudo, usamos a metodologia POT para estimar os parâmetros da distribuição dos excessos na aplicação ao salto em comprimento do atletismo, no período de 1935 a 2016 nos homens e de 1964 a 2016 nas mulheres. Determinado o limiar u, adequado, são apresentadas as estimativas de alguns parâmetros de interesse, como a probabilidade de excedência, os quantis extremais, o limite superior do suporte e os níveis e períodos de retorno. Nos homens, os resultados apontam para u=8,45m com 0 ˆ   e nas mulheres u = 7,06m com 0 ˆ   . Prevê-se que o recorde mundial seja batido, em média, acima de 585 recordes individuais nos homens, e acima de 427 recordes individuais nas mulheres.
简介:高峰超过阈值(派)的方法是广义帕累托分布调整过度独立同分布随机above a高阈值。在本研究中,我们使用POT方法估计了1935 - 2016年男性和1964 - 2016年女性在跳远运动中的过量分布参数。确定了合适的阈值u,给出了一些感兴趣的参数的估计,如超过概率、极值分位数、支持上限、水平和回报周期。男人,45米,结果都指向u = 8 0ˆ女性和u = 7, 06码0ˆ。据预测,平均而言,男性将打破585项个人纪录,女性将打破427项个人纪录。
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引用次数: 0
BAYESIAN AND FREQUENTIST APPROACHES FOR FITTING THE GAMMA-TIME-DEPENDENT MODEL TO DESCRIBE NEUTRAL DETERGENT FIBER DEGRADATION 贝叶斯和频率方法拟合伽马时间依赖模型来描述中性洗涤剂纤维降解
Q4 Medicine Pub Date : 2018-09-26 DOI: 10.28951/RBB.V36I3.260
H. Bonfá, E. Detmann, F. F. Silva, J. Figueiras
The aim of the study was evaluate and compare the efficiency of Bayesian and frequentist approach to describe the rumen degradation of NDF. Simulated data was composed by four scenarios: regular restriction in the number of incubation times, random loss of incubation times, loss of specific parts of degradation curves, variation in the precision of the incubations procedures. Two real datasets was used, these real data encompassed the evaluation of NDF degradation of a tropical grass (Brachiaria decumbes).  The model was fitted according their characteristics approach and compared by plots and assessors. The Bayesian and frequentist approach presented reliable estimates of degradation parameters for the majority of the data tested. Therefore, in specific cases with short random records number, the Bayesian approach showed greater bias of the estimates of incubation residue and estimates  of degradation rate without a biological coherence of the parameters, compared to frequentist  inference. In another words, the Bayesian approach fitted with prior diffuse, presented less flexible. Nevertheless, it is emphasized the importance of the background information before the modeling, mainly  for the Bayesian approach, in order to define proper prior distributions. Future thorough studies about the influence of non-informative prior for the parameters are necessary.
本研究的目的是评估和比较贝叶斯方法和频率方法描述NDF瘤胃降解的效率。模拟数据由四种情况组成:孵育次数有规则限制、孵育时间随机丢失、降解曲线特定部分丢失、孵育过程精度变化。使用了两个真实数据集,这些真实数据包括对热带草(Brachiaria decumbes) NDF退化的评估。根据它们的特征方法拟合模型,并通过图和评估器进行比较。贝叶斯和频率方法为大多数测试数据提供了可靠的退化参数估计。因此,在随机记录数量较短的特定情况下,与频率推断相比,贝叶斯方法在没有参数的生物一致性的情况下,对孵育残留物和降解率的估计显示出更大的偏差。换句话说,贝叶斯方法与先验扩散相适应,表现出较低的灵活性。然而,强调背景信息在建模之前的重要性,主要是为了贝叶斯方法,以定义适当的先验分布。未来有必要深入研究非信息先验对参数的影响。
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引用次数: 0
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Revista Brasileira de Biometria
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