JBI evidence synthesis最新文献

Objective: The objective of this review is to explore the experiences of rehabilitation professionals in the provision of palliative care.

Introduction: Despite the growing recognition of the importance of rehabilitation in palliative care, the integration of rehabilitation professionals into palliative care teams is not widespread.

Eligibility criteria: This review will explore the lived experiences of rehabilitation professionals in palliative care, particularly their perceptions, challenges, rewards, and role impact. It will include qualitative and mixed methods studies conducted across diverse palliative care settings.

Methods: This review will follow the JBI methodology for qualitative synthesis. The search strategy will include PubMed, CINAHL (EBSCOhost), Embase (Ovid), Web of Science, PEDro, as well as gray literature sources and citation searching. The search results and study selection process will be presented using a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram. Critical appraisal, data extraction, and meta-aggregation will be conducted by 2 reviewers independently. The synthesized findings and their ConQual scores will be used to inform the review's recommendations.

Review registration: PROSPERO CRD42025639926.

Objective: This review will assess and synthesize the available qualitative evidence on the experiences of parents of children with cleft lip, cleft palate, or cleft lip and palate.

Introduction: Parents of children with cleft lip and/or palate often experience emotional concerns such as shock or denial upon learning of their child's condition. The parents may also experience challenges related to physical issues such as feeding difficulties, surgical procedures, and speech articulation disorders. By understanding these experiences, we aim to suggest potential resources or enhancements of care for these parents.

Eligibility criteria: We will consider all primary studies reporting on the experiences of biological parents of children under 18 years with cleft lip and/or palate. We will focus on qualitative research as well as mixed methods studies that incorporate qualitative data. Experiences in any context will be included, regardless of the parents' age, sex/gender, or type of cleft lip and/or palate.

Methods: We will search for published and unpublished studies across 5 databases and 1 website: MEDLINE (Ovid), CINAHL (EBSCOhost), PsycINFO (EBSCOhost), DANS-Easy, and ProQuest Dissertations and Theses Global, and the American Cleft Palate Craniofacial Association. The reference lists of studies selected for critical appraisal will also be examined for additional relevant studies. There will be no restrictions on language or publication date. Two independent reviewers will screen studies for inclusion, assess methodological quality using the JBI critical appraisal checklist, extract data, and perform meta-aggregation. Confidence in the synthesized findings will be assessed according to the ConQual approach.

Review registration: PROSPERO CRD42024584995.

Objective: The objective of this systematic review is to explore the experiences of help-seeking among adolescents with depression, with a specific focus on understanding the experiences and exploring the facilitators and barriers to seeking help for depression.

Introduction: Depression is recognized as a serious mental health problem among adolescents, characterized by its high prevalence and significant burden. Help-seeking plays a crucial role in managing depression, yet little is known about the experiences of adolescents seeking help for depression.

Eligibility criteria: This review will include studies on adolescents aged 10 to 19 years, as well as studies with a mean participant age within this range, who are experiencing or have experienced depression. Studies that include experiences of help-seeking for depression, including barriers and facilitators, will be considered. Studies may be conducted in diverse settings, including hospitals, health care centers, schools, and participants' homes.

Methods: PubMed, Embase (Ovid), CINAHL (EBSCOhost), Cochrane Library (CENTRAL), PsycINFO, Web of Science, Scopus, CNKI (a Chinese medical literature database), Wanfang, and WEIPU databases will be systematically searched for relevant articles. Two reviewers will independently select studies, extract data, and critically assess the methodological quality. Meta-aggregation will be conducted to synthesize the data, and the ConQual approach will be applied to establish confidence in the synthesized findings.

Review registration: PROSPERO CRD42024573138.

Objective: The objective of this scoping review is to understand the nature of the published evidence on housing suitability, affordability, insecurity, and homelessness in relation to physical and mental health, domestic violence, and health service use among Indigenous people in high-income countries.

Introduction: The historical injustices of colonization, dispossession, and racism have created unique housing challenges influencing the health gap for Indigenous people in high-income countries. Understanding the breadth and nature of research in the area of housing and Indigenous health is key for establishing a research agenda that fills knowledge gaps and informs culturally appropriate housing initiatives.

Eligibility criteria: This review will consider quantitative studies, or the quantitative components of mixed methods studies, set in high-income countries investigating housing suitability, affordability, insecurity, and/or homelessness for Indigenous people in relation to physical and mental health, domestic violence, and health service use. Studies employing qualitative methodologies will not be considered.

Methods: Informed by Indigenous perspectives, the review will follow the JBI methodology for scoping reviews, along with enhancements for Indigenous research outlined by Brodie et al. Databases to be searched include MEDLINE (Ovid), Embase (Ovid), Emcare (Ovid), Scopus, CINAHL (EBSCOhost), PsycINFO (Ovid), and Informit Indigenous Collection. Studies will be limited to those published in English since the year 2000. Two or more reviewers will screen studies and extract data. Information on study characteristics, populations, settings, methods, concepts, outcome measures, and alignment with Indigenous research principles will be synthesized and presented in tabular and graphical formats, with an accompanying narrative summary.

Review registration: OSF https://osf.io/8d92m.

Objective: This systematic review will assess the cost-effectiveness of clopidogrel in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI).

Introduction: Antiplatelet drugs, including clopidogrel, ticagrelor, prasugrel, and aspirin, are crucial in managing ACS, preventing ischemia, and, ultimately, death in PCI patients. Clopidogrel is the main treatment for those who have undergone PCI, used either alone or with aspirin. The incidence of ACS is rising globally, and is a major cause of premature death for millions. ACS management involves continuous medical therapy and costly procedures such as PCI, significantly straining health care resources.

Eligibility criteria: Studies will be eligible for inclusion if they report on the cost-effectiveness of clopidogrel in patients with ACS compared with other antiplatelet drugs.

Methods: This systematic review will adhere to the JBI methodology for systematic reviews of economic evaluation evidence. A preliminary search was conducted of MEDLINE (PubMed) using MeSH terms. Two independent reviewers will screen records at the title/abstract level, followed by full-text screening. Two reviewers will then assess methodological quality and extract data as per JBI guidelines. The JBI Dominance Ranking Matrix for economic evaluations will be used to summarize and compare the included studies. The cost-effectiveness measures will be incremental cost, incremental cost per quality-adjusted life year gained, or incremental cost per disability-adjusted life year averted. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach will be used to appraise the certainty of economic evidence, such as using resources and expenditure, for incorporating the results into the decision-making process.

Review registration: PROSPERO CRD42024504614.

Objective: The objective of this review is to synthesize qualitative evidence on the parenting experiences of informal caregivers of preterm infants during their corrected age of 2 years.

Introduction: Preterm infants, born before 37 weeks' gestation, are at high risk of growth and neurodevelopmental delays. The parenting journey for these infants presents unique challenges from birth to the transition home, particularly during the infants' corrected age of 2 years. Understanding informal caregivers' experiences during this critical time enables health care providers to deliver timely and appropriate interventions for both caregivers and infants; however, qualitative evidence synthesizing this area of research remains limited.

Eligibility criteria: This review will examine qualitative data on the parenting experiences (ie, challenges) of informal caregivers of preterm infants from birth to a corrected age of 2 years. Informal caregivers may include parents, grandparents, and other relatives (biological or non-biological) who have a personal relationship with the infant. All informal caregivers will be included, regardless of age, gender, or social or marital status. Caregivers of infants with congenital anomalies or chromosomal abnormalities will be excluded from the review.

Methods: This review will adhere to the JBI approach for qualitative systematic reviews. The search strategy aims to identify both published and unpublished studies, with no restrictions on publication year. Studies published in English or Thai will be sourced from PubMed, CINAHL (EBSCOhost), and Embase (EBSCOhost). Additionally, sources of unpublished studies and gray literature will be explored, including the Mahidol University Library Catalog (OPAC), Open Access Theses and Dissertations (OATD), and ThaiJo (Thai Journals Online). Two reviewers will independently assess the methodological validity of the selected qualitative papers prior to their inclusion in the review. Data synthesis will employ the meta-aggregation approach, and the synthesized findings will be evaluated using the ConQual approach.

Review registration: PROSPERO CRD42024606504.

Objective: The objective of the review is to estimate the global incidence of congenital syphilis, adverse events, and death in children under 2 years of age born to mothers with syphilis.

Introduction: Untreated or inadequately treated maternal syphilis leads to adverse birth outcomes that are often severe, including stillbirth, neonatal death, prematurity, low birth weight, congenital malformations, and congenital syphilis in infants.

Eligibility criteria: This review includes studies involving fetuses and children under 2 years of age diagnosed with Treponema pallidum (syphilis) infection via microscopy or serology and whose mothers were diagnosed with syphilis, irrespective of maternal treatment status.

Methods: This systematic review will follow the methodology outlined by the Prevalence Estimates Reviews - Systematic Review Methodology Group (PERSyst). The search strategy will be conducted across databases including PubMed, CINAHL (EBSCOhost), Web of Science, ScienceDirect, Embase, Scopus, Latin American and Caribbean Health Sciences Literature (BVS), CUIDEN (Fundación Index), Networked Digital Library of Theses and Dissertations, Brazilian Digital Library of Theses and Dissertations, CAPES Theses and Dissertations, and ProQuest Dissertations and Theses. The studies will be critically appraised by 2 reviewers independently. If sufficient data are available, a meta-analysis will be performed; otherwise, findings will be presented narratively, including tables and figures to support data presentation, where appropriate.

Review registration: PROSPERO CRD42024581281.