Objective: The objective of this review will be to synthesize the experiences and perceptions of adult medical inpatients regarding discharge education provided by health care professionals during their hospital stay, when patients are discharged from hospital to home.
Introduction: Discharge education is an essential part of patient care, helping individuals prepare to manage their health once they leave the hospital. Many patients face significant challenges in adjusting to life outside the hospital following discharge, and these challenges can provide valuable insights into their needs in terms of the discharge process.
Eligibility criteria: This review will consider qualitative studies exploring the perceptions and experiences of adult medical inpatients who received discharge education from health care professionals and were discharged from hospital to home. Studies published in English and Portuguese, regardless of publication date or geographic origin, will be eligible.
Methods: This review will follow the JBI methodology for systematic reviews of qualitative evidence. A comprehensive literature search will be conducted across the following databases: PubMed, CINAHL (EBSCOhost), Scopus, Embase (Ovid), Emcare (Ovid), LILACS (BVS), and ERIC (EBSCOhost). ProQuest Dissertations & Theses Global will be searched for gray literature. Two reviewers will independently screen and appraise studies and then extract data. For data synthesis, a meta-aggregative approach will be used. The ConQual approach will be employed for assessing the confidence in the evidence. The results of the search and the study inclusion process will be reported in full in the final systematic review and presented in a Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram.
Systematic review registration number: PROSPERO CRD420250641761 https://www.crd.york.ac.uk/prospero/.
Objective: This systematic review will provide an overview of economic evaluation studies of interventions for acute ischemic stroke, including intravenous thrombolysis, endovascular thrombectomy, antiplatelet therapy, and emerging strategies such as mobile stroke units and remote robotic thrombectomy, across different health care settings and patient populations.
Introduction: Acute ischemic stroke is a leading cause of disability and mortality, imposing significant economic burdens on health care systems. While various interventions improve clinical outcomes, their economic evidence remains uncertain.
Eligibility criteria: Studies will be eligible if they include adult patients receiving any intervention for acute ischemic stroke . Eligible studies will report economic evaluations (full or partial) of the treatment of acute ischemic stroke.
Methods: A systematic search of academic, non-academic, and gray literature databases will be conducted. Two reviewers will independently screen studies and full texts against criteria. Methodological quality will be assessed using the JBI checklist for economic evaluations. Data will be extracted using a modified JBI data extraction form. For standardization across studies, cost data will be converted to a uniform base year and a single currency using the CCEMG-EPPI Centre Cost Converter. The JBI dominance ranking matrix will be used to summarize and compare the results of the different types of economic evaluations. Based on the incremental costs and effectiveness extracted from the studies, net monetary benefits will be calculated and, if feasible, explored in a meta-analysis. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach will be used to assess the certainty of economic evidence.
Review registration: PROSPERO CRD420250651215.
Objective: The review will examine the association between nomophobia and health outcomes among university students.
Introduction: Nomophobia is characterized by the fear of losing access or connectivity to one's mobile phone, due to issues such as technical problems, battery depletion, or involuntary separation. As nomophobia is a relatively recent problem, data quantifying the adverse effects are crucial, and its relationship with physical, psychological, and psychosocial health consequences among university students remains unclear.
Eligibility criteria: This review will include cross-sectional, case-control, and cohort studies focusing on university students, regardless of their sex and geographic location, who were assessed to be nomophobic (based on the Nomophobia Questionnaire [NMP-Q] developed in 2015), that report their physical, psychological, and psychosocial health consequences due to nomophobia.
Methods: This review will follow the JBI methodology for systematic reviews of etiology and risk. Academic and non-academic databases and gray literature will be searched, including MEDLINE (Ovid), Embase (Ovid), CINAHL (EBSCOhost), Cochrane CENTRAL, Web of Science Core Collection, ProQuest, Health and Medical Collection (ProQuest), PsycINFO (Ovid), and Google Scholar (up to 20 pages). Titles, abstracts, and full texts of included studies will be screened by 2 independent reviewers, with any disagreements resolved by a third reviewer. Critical appraisal will be conducted using JBI checklists. Where possible, the studies will be pooled using random effects meta-analysis. If statistical pooling is not possible, the findings will be presented in narrative format, including tables and figures. Certainty of the evidence will be assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.
Review registration: PROSPERO CRD420251002138.
Objective: The objective of this scoping review is to identify how school-based nursing programs that support children with special health care needs (CSHCN) are structured and implemented globally.
Introduction: The number of CSHCN living and participating in the community is increasing due to medical and technological advances. To participate fully in school, CSHCN may require support for a wide range of health conditions. There is minimal research that synthesizes the development and implementation of school-based nursing programs and interventions, particularly in Canada.
Eligibility criteria: Academic and gray literature will be considered for inclusion. Included sources must refer to school-aged children (pre-primary through 12) and discuss a school-based nursing program or intervention that targets medical or health needs. Literature reviews will be excluded from this review; however, their reference lists will be scanned for relevant studies. There are no restrictions on geographical location or date of publication, but only studies published in English will be considered for inclusion.
Methods: This scoping review will be conducted using the JBI methodology for scoping reviews. A search strategy has been developed using the Population, Concept, Context (PCC) mnemonic. The search has been developed in MEDLINE (Ovid) and will be translated to Embase, CINAHL, and Scopus, and reported in a Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). The Reach, Effectiveness, Adoption, Implementation, and Maintenance Framework (RE-AIM) will be used to categorize the range of implementation strategies across included studies. Findings related to determinants (facilitators and barriers) will be organized according to the Consolidated Framework for Implementation Research.
Review registration: OSF.
Objective: This qualitative systematic review will aim to explore the barriers and facilitators of the use of digital adherence technologies for tuberculosis treatment. The review will focus on the human factors that support the use of these technologies in tuberculosis treatment.
Introduction: More than 10 million people are infected with tuberculosis every year. Failure to adhere to the treatment regimen is the key reason for the disease's continuing burden worldwide. Numerous efforts have been made to address non-adherence to treatment, including the use of digital adherence technologies. However, recent studies on such technologies show conflicting findings about their effectiveness.
Eligibility criteria: This review will consider studies reporting on patients and health care workers and the use of digital tools for tuberculosis treatment adherence. The review will include studies that focus on drug-sensitive tuberculosis, drug-resistant tuberculosis, and latent tuberculosis infection, as well as studies on patients with tuberculosis and common comorbidities, such as diabetes or human immunodeficiency virus.
Methods: This review will follow the JBI methodology for qualitative systematic reviews. PubMed, Embase (Ovid), Scopus, and Emcare (Ovid) will be searched for published studies. Searches will also be conducted for gray literature. Two reviewers will independently conduct study selection, critical appraisal, data extraction, and data synthesis. The ConQual approach will be used to assess confidence in the findings of the meta-aggregated data. There will be no date or language limitations.
Review registration: PROSPERO CRD42025645171.
Introduction: The weighted mean difference (WMD) has long been used in evidence syntheses involving continuous outcomes. However, it is sometimes applied interchangeably with the mean difference (MD) despite their conceptual distinction: the WMD is intended solely for pooled estimates across studies, not for individual study results. Misuse of WMD can lead to ambiguity in reporting and interpretation, yet empirical evidence on their prevalence and patterns in published systematic reviews and meta-analyses (SRMAs) remains limited.
Methods: We conducted a meta-epidemiological study of SRMAs reporting continuous outcomes, published in The BMJ during 2 periods: 2002-2007 and 2020-2025. Each article was evaluated to determine whether the WMD was reported, whether its use was appropriate, and the rationale for each assessment. Two authors independently performed the evaluations, and any disagreements were resolved through discussion.
Results: In the earlier study period, misuse of the term WMD was widespread, with many SRMAs employing it interchangeably with the MD without clear justification. Over time, the frequency of such misuse decreased, coinciding with the broader adoption of reporting guidelines and increased methodological rigor. Nonetheless, inappropriate applications of WMD persist in more recent publications.
Conclusions: Persistent inconsistencies in WMD use reveal gaps in methodological understanding and reporting practice. Ongoing efforts to refine guidance and promote evidence synthesis literacy are essential to improve the rigor and transparency of SRMAs.
Objective: The objective of this review is to evaluate whether the presence and severity of the dysplastic margin predicts recurrence or survival outcomes in patients with primary oral squamous cell carcinoma (OSCC) resected with curative intent.
Introduction: There is variable evidence whether a dysplastic OSCC margin predicts worse recurrence or survival outcomes and, therefore, no consensus on whether a dysplastic margin should be regarded as an involved margin. Ambiguity of the prognostic significance of dysplasia in the resection margin means that management is institutionally dependent.
Inclusion criteria: This systematic review will include studies of patients with primary OSCC who have undergone surgery with curative intent, with or without adjuvant treatment. Studies will be included if they compare the recurrence and survival outcomes of dysplastic margins compared with clear, close, or involved margins.
Methods: PubMed, Embase (Ovid), Web of Science Core Collection, Scopus, and gray literature will be searched. Two reviewers will independently undertake title/abstract and full-text screening. Included studies will be critically appraised using the QUIPS tool. Data extraction will use the CHARMS-PF checklist. Odds ratio, risk ratios, and hazard ratios along with standard errors, variances, or CIs will be extracted. Where possible, hazard ratios will be computed if not directly reported. Separate meta-analyses will be done for odds ratios, univariate hazard ratios, and multivariate hazard ratios. If meta-analysis is not possible, data will be synthesized narratively. The certainty of evidence will be assessed using the GRADE approach, and a Summary of Findings will be presented.
Review registration: PROSPERO CRD42024604073.
Objective: This scoping review will identify and describe available datasets collected nationally to measure public mental health in Australia. The review will also identify gaps in current data collection by mapping the identified datasets to the priorities of the National Mental Health and Suicide Prevention Agreement (2022).
Introduction: Australia's public mental health data collection has been fragmented by multiple initiatives and jurisdictional inconsistency. Data largely focus on service input and activity, ignoring other factors such as social determinants, prevention, and early intervention. To effectively assess and monitor Australia's mental health, researchers and policymakers need data that are consistent, inclusive, appropriate, and holistic.
Eligibility criteria: This scoping review focuses on Australian national data for public mental health surveillance, encompassing mental health promotion, symptoms, disorders, services, workforce, and prevention. Mental health conditions outside DSM-5 or ICD-11 will be excluded.
Methods: The review will be conducted in accordance with the JBI methodology for scoping reviews and Godin's gray literature search methods. The search strategy will involve hand-searching target websites. Language and region will be limited to English and Australia. Publication date will not be restricted. Search results, dataset selection, and data extraction will be recorded in an Excel spreadsheet. Two rounds of screening will be conducted to finalize selection. Data will be extracted using an extraction table developed by the reviewers based on JBI methodology. Extracted data will be categorized into meaningful groups to answer the review questions. Data will be presented in tables and/or diagrams, accompanied by narrative summary.
Review registration: OSF https://osf.io/sa756.
Objective: This umbrella review will aim to assess the effectiveness of support interventions for improving well-being outcomes in parents of preterm infants.
Introduction: Preterm birth presents significant emotional, psychological, and social challenges for parents, often adversely affecting their well-being. Numerous systematic reviews have examined support interventions aimed at improving parental outcomes. An umbrella review is warranted to synthesize and critically appraise this diverse evidence. Such a review could guide health care professionals in implementing effective, evidence-based strategies to support parents throughout the parenthood journey of preterm infants.
Eligibility criteria: This umbrella review will include systematic reviews that examine the effectiveness of support interventions designed to enhance the well-being of parents of preterm infants. All types of support interventions will be considered, regardless of the parents' gender or age, the infants' gestational age, or the contextual setting.
Methods: This review will follow the JBI methodology for umbrella reviews. A comprehensive search will be conducted across PubMed, the Cochrane Database of Systematic Reviews, CINAHL (EBSCOhost), Embase (Embase.com), Scopus, Open Access Theses and Dissertations (OATD), and the Mahidol Library Catalog (OPAC) to identify relevant reviews. There will be no date or language limitations. Two reviewers will independently screen titles, abstracts, and full texts using predefined eligibility criteria. The methodological quality of the included reviews will be assessed using the JBI checklist for systematic reviews and research syntheses. Data will be extracted using a piloted, adapted JBI tool. Findings will be presented in tables with narrative summaries, visual aids, and a citation matrix to assess study overlap.
Review registration: PROSPERO CRD420251071668.

