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Informal caregivers' feeding experiences for children with cancer: a systematic review of qualitative evidence. 非正式照顾者对癌症儿童的喂养经验:对定性证据的系统回顾。
IF 4.5 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-28 DOI: 10.11124/JBIES-25-00221
Donruedee Kamkhoad, Tippawan Srichalerm, Porawan Witwaranukool
<p><strong>Objective: </strong>This review synthesizes informal caregivers' experiences of feeding children with cancer.</p><p><strong>Introduction: </strong>Alterations in eating behaviors among children with cancer affect their nutritional status, resulting in various adverse consequences. Besides interventions provided by health care professionals, the role of informal caregivers, often parents, family members, or relatives, in supporting and maintaining adequate nutrition is equally important. Exploring informal caregivers' experiences in feeding their children can offer valuable insights for enhancing nutritional care.</p><p><strong>Eligibility criteria: </strong>This review included qualitative studies, as well as the qualitative components of mixed method studies, examining the experiences of informal caregivers in feeding children with cancer aged 2 to 18 years. Caregivers of any gender or age were included. Studies published in English or Thai up to August 18, 2025, were considered.</p><p><strong>Methods: </strong>This review followed the JBI approach for qualitative systematic reviews. Published and gray literature were searched in PubMed, Embase (Ovid), CINAHL (EBSCOhost), Scopus, LILACS (BVS), ThaiJO (TCI), and ProQuest Dissertations and Theses (ProQuest). No language restrictions were applied and no date limit was set. Reference lists of the included studies were searched for additional relevant studies. Two independent reviewers separately screened for eligible studies and performed the critical appraisal. Two reviewers extracted the data, and 3 reviewers conducted the synthesis using meta-aggregation, and summarized the findings. The final synthesized findings were graded using the ConQual approach.</p><p><strong>Results: </strong>A total of 28 studies across 13 countries, spanning 6 continents were included, with 137 extracted findings (unequivocal=135, credible=2) and narrative illustrations. These findings were combined to form 19 categories based on similarity in meaning and 4 synthesized findings: i) Informal caregivers of children with cancer adapted their meal preparation strategies, at times prioritizing a child's intake over nutritional value when appetite is poor; ii) Informal caregivers of children with cancer used a spectrum of strategies during mealtimes to support nutritional intake, from positive encouragement and incentivization to more coercive tactics; iii) Informal caregivers of children with cancer perceived their children's altered eating behaviors as significantly affecting caregivers' well-being and family dynamics; and iv) Informal caregivers of children with cancer face feeding-related difficulties shaped by both personal understanding and external support systems.</p><p><strong>Conclusions: </strong>This review highlights the diverse feeding strategies used by caregivers during meal preparation and mealtimes. Caregivers reported difficulties in managing their children's altered eating behaviors, such as em
目的:综述非正式护理人员喂养癌症患儿的经验。导读:癌症儿童饮食行为的改变会影响其营养状况,导致各种不良后果。除了卫生保健专业人员提供的干预措施外,非正式照料者,通常是父母、家庭成员或亲属,在支持和维持适当营养方面的作用也同样重要。探索非正规照料者喂养儿童的经验,可以为加强营养护理提供宝贵的见解。资格标准:本综述包括定性研究,以及混合方法研究的定性部分,检查非正式照顾者喂养2至18岁癌症儿童的经验。包括任何性别和年龄的照顾者。在2025年8月18日之前以英语或泰语发表的研究被纳入考虑范围。方法:本综述采用JBI方法进行定性系统评价。在PubMed、Embase (Ovid)、CINAHL (EBSCOhost)、Scopus、LILACS (BVS)、ThaiJO (TCI)和ProQuest Dissertations and Theses (ProQuest)中检索已发表的和灰色的文献。没有使用语言限制,也没有设定日期限制。检索纳入研究的参考文献,寻找其他相关研究。两名独立的审稿人分别筛选符合条件的研究并进行批判性评估。2名审稿人提取资料,3名审稿人采用meta-aggregation进行综合,并对结果进行总结。使用征服方法对最终的综合结果进行评分。结果:共纳入了横跨6大洲的13个国家的28项研究,其中有137项提取结果(明确=135,可信=2)和叙述性插图。这些发现根据意义上的相似性和4个综合发现合并成19个类别:i)癌症儿童的非正式照顾者调整了他们的膳食准备策略,有时在食欲不佳时优先考虑儿童的摄入量而不是营养价值;ii)癌症儿童的非正式照顾者在用餐时间使用一系列策略来支持营养摄入,从积极的鼓励和激励到更强制的策略;iii)癌症儿童的非正式照护者认为,儿童饮食行为的改变显著影响了照护者的幸福感和家庭动态;癌症儿童的非正式照顾者面临着由个人理解和外部支持系统形成的与喂养有关的困难。结论:本综述强调了护理人员在膳食准备和用餐时间使用的不同喂养策略。照顾者报告说,在管理孩子改变的饮食行为方面存在困难,比如个人层面的情绪困扰,以及家庭层面的共享膳食中断。还确定了多层次的促进因素和未满足的需求,包括难以理解孩子的经历和亲戚的支持,但获得量身定制的饮食指导的机会有限。因此,卫生保健提供者应提供实用的饮食建议和支持,以减轻照顾者的负担,同时促进儿童的营养健康。未来的研究应该探索儿童癌症诊断前后的喂养经历,以提供更全面的了解。评审注册号:PROSPERO CRD42024501382。
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引用次数: 0
Medical inpatient experiences and perceptions of discharge education provided by health care professionals: a qualitative systematic review protocol. 由卫生保健专业人员提供的医疗住院病人经验和出院教育的看法:一个定性的系统评价方案。
IF 4.5 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-28 DOI: 10.11124/JBIES-25-00169
Ariane Sabina Stieven, Sonia Hines, Romy Jia, Cindy Stern, Maria do Carmo Fernandez Lourenço Haddad

Objective: The objective of this review will be to synthesize the experiences and perceptions of adult medical inpatients regarding discharge education provided by health care professionals during their hospital stay, when patients are discharged from hospital to home.

Introduction: Discharge education is an essential part of patient care, helping individuals prepare to manage their health once they leave the hospital. Many patients face significant challenges in adjusting to life outside the hospital following discharge, and these challenges can provide valuable insights into their needs in terms of the discharge process.

Eligibility criteria: This review will consider qualitative studies exploring the perceptions and experiences of adult medical inpatients who received discharge education from health care professionals and were discharged from hospital to home. Studies published in English and Portuguese, regardless of publication date or geographic origin, will be eligible.

Methods: This review will follow the JBI methodology for systematic reviews of qualitative evidence. A comprehensive literature search will be conducted across the following databases: PubMed, CINAHL (EBSCOhost), Scopus, Embase (Ovid), Emcare (Ovid), LILACS (BVS), and ERIC (EBSCOhost). ProQuest Dissertations & Theses Global will be searched for gray literature. Two reviewers will independently screen and appraise studies and then extract data. For data synthesis, a meta-aggregative approach will be used. The ConQual approach will be employed for assessing the confidence in the evidence. The results of the search and the study inclusion process will be reported in full in the final systematic review and presented in a Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram.

Systematic review registration number: PROSPERO CRD420250641761 https://www.crd.york.ac.uk/prospero/.

目的:本综述的目的是综合成人住院患者在出院回家时,对医疗保健专业人员在其住院期间提供的出院教育的经验和看法。出院教育是病人护理的重要组成部分,帮助个人准备管理他们的健康,一旦他们离开医院。许多患者在出院后适应医院外的生活时面临着重大挑战,这些挑战可以为他们在出院过程中的需求提供有价值的见解。资格标准:本综述将考虑定性研究,探讨接受卫生保健专业人员出院教育并出院回家的成年住院患者的看法和经历。以英语和葡萄牙语发表的研究,无论出版日期或地理来源如何,都将符合条件。方法:本综述将遵循JBI方法对定性证据进行系统评价。全面的文献检索将在以下数据库进行:PubMed, CINAHL (EBSCOhost), Scopus, Embase (Ovid), Emcare (Ovid), LILACS (BVS)和ERIC (EBSCOhost)。ProQuest dissertation & Theses Global将搜索灰色文献。两名审稿人将独立筛选和评估研究,然后提取数据。对于数据综合,将使用元聚合方法。将采用征服方法来评估证据的可信度。搜索结果和研究纳入过程将在最终的系统综述中完整报告,并在系统综述和荟萃分析的首选报告项目流程图中展示。系统评价注册号:PROSPERO CRD420250641761 https://www.crd.york.ac.uk/prospero/。
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引用次数: 0
Economic evaluations of interventions for acute ischemic stroke: a systematic review protocol. 急性缺血性卒中干预措施的经济评价:一项系统评价方案。
IF 4.5 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-28 DOI: 10.11124/JBIES-25-00134
Madhusudan Prasad Singh, Ekta Krishna, Meenalotchini Prakash Gurunthalingam, Denny John

Objective: This systematic review will provide an overview of economic evaluation studies of interventions for acute ischemic stroke, including intravenous thrombolysis, endovascular thrombectomy, antiplatelet therapy, and emerging strategies such as mobile stroke units and remote robotic thrombectomy, across different health care settings and patient populations.

Introduction: Acute ischemic stroke is a leading cause of disability and mortality, imposing significant economic burdens on health care systems. While various interventions improve clinical outcomes, their economic evidence remains uncertain.

Eligibility criteria: Studies will be eligible if they include adult patients receiving any intervention for acute ischemic stroke . Eligible studies will report economic evaluations (full or partial) of the treatment of acute ischemic stroke.

Methods: A systematic search of academic, non-academic, and gray literature databases will be conducted. Two reviewers will independently screen studies and full texts against criteria. Methodological quality will be assessed using the JBI checklist for economic evaluations. Data will be extracted using a modified JBI data extraction form. For standardization across studies, cost data will be converted to a uniform base year and a single currency using the CCEMG-EPPI Centre Cost Converter. The JBI dominance ranking matrix will be used to summarize and compare the results of the different types of economic evaluations. Based on the incremental costs and effectiveness extracted from the studies, net monetary benefits will be calculated and, if feasible, explored in a meta-analysis. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach will be used to assess the certainty of economic evidence.

Review registration: PROSPERO CRD420250651215.

目的:本系统综述将概述急性缺血性卒中干预措施的经济评估研究,包括静脉溶栓、血管内取栓、抗血小板治疗和新兴策略,如移动卒中单元和远程机器人取栓,在不同的医疗机构和患者群体中。急性缺血性中风是致残和死亡的主要原因,给卫生保健系统带来了重大的经济负担。虽然各种干预措施改善了临床结果,但其经济证据仍不确定。入选标准:纳入接受任何急性缺血性卒中干预的成年患者的研究均符合入选标准。符合条件的研究将报告急性缺血性卒中治疗的经济评估(全部或部分)。方法:系统检索学术、非学术和灰色文献数据库。两名审稿人将根据标准独立筛选研究和全文。方法学质量将使用JBI经济评价检查表进行评估。将使用修改后的JBI数据提取表单提取数据。为了使研究标准化,成本数据将使用ccemg - epi中心成本转换器转换为统一的基准年和单一货币。JBI优势排序矩阵将用于总结和比较不同类型经济评价的结果。根据从研究中提取的增量成本和有效性,将计算净货币效益,如果可行,将在荟萃分析中进行探讨。建议、评估、发展和评价的分级(GRADE)方法将用于评估经济证据的确定性。评审注册号:PROSPERO CRD420250651215。
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引用次数: 0
Association of nomophobia and health consequences among university students: a systematic review protocol. 大学生无手机恐惧症与健康后果的关联:一项系统评价方案。
IF 4.5 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-28 DOI: 10.11124/JBIES-25-00252
Shwetha Ashok, Bhargavi Gongati, Denny John

Objective: The review will examine the association between nomophobia and health outcomes among university students.

Introduction: Nomophobia is characterized by the fear of losing access or connectivity to one's mobile phone, due to issues such as technical problems, battery depletion, or involuntary separation. As nomophobia is a relatively recent problem, data quantifying the adverse effects are crucial, and its relationship with physical, psychological, and psychosocial health consequences among university students remains unclear.

Eligibility criteria: This review will include cross-sectional, case-control, and cohort studies focusing on university students, regardless of their sex and geographic location, who were assessed to be nomophobic (based on the Nomophobia Questionnaire [NMP-Q] developed in 2015), that report their physical, psychological, and psychosocial health consequences due to nomophobia.

Methods: This review will follow the JBI methodology for systematic reviews of etiology and risk. Academic and non-academic databases and gray literature will be searched, including MEDLINE (Ovid), Embase (Ovid), CINAHL (EBSCOhost), Cochrane CENTRAL, Web of Science Core Collection, ProQuest, Health and Medical Collection (ProQuest), PsycINFO (Ovid), and Google Scholar (up to 20 pages). Titles, abstracts, and full texts of included studies will be screened by 2 independent reviewers, with any disagreements resolved by a third reviewer. Critical appraisal will be conducted using JBI checklists. Where possible, the studies will be pooled using random effects meta-analysis. If statistical pooling is not possible, the findings will be presented in narrative format, including tables and figures. Certainty of the evidence will be assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.

Review registration: PROSPERO CRD420251002138.

目的:探讨大学生无手机恐惧症与健康状况的关系。导读:无手机恐惧症的特点是担心由于技术问题、电池耗尽或非自愿分离等问题而失去与手机的连接。由于恐无症是一个相对较新的问题,量化其不良影响的数据至关重要,其与大学生身体、心理和社会心理健康后果的关系尚不清楚。入选标准:本综述将包括针对大学生的横断面、病例对照和队列研究,无论其性别和地理位置,均被评估为无手机恐惧症(基于2015年开发的无手机恐惧症问卷[NMP-Q]),报告他们因无手机恐惧症而导致的身体、心理和社会心理健康后果。方法:本综述将遵循JBI方法对病因和风险进行系统评价。学术和非学术数据库和灰色文献将被检索,包括MEDLINE (Ovid), Embase (Ovid), CINAHL (EBSCOhost), Cochrane CENTRAL, Web of Science Core Collection, ProQuest, Health and Medical Collection (ProQuest), PsycINFO (Ovid)和谷歌Scholar(最多20页)。纳入研究的标题、摘要和全文将由2名独立审稿人筛选,任何异议由第三名审稿人解决。关键评估将使用JBI检查清单进行。在可能的情况下,这些研究将使用随机效应荟萃分析进行汇总。如果统计汇集不可能,调查结果将以叙述形式提出,包括表格和数字。证据的确定性将采用建议、评估、发展和评价分级(GRADE)方法进行评估。评审注册号:PROSPERO CRD420251002138。
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引用次数: 0
Structure and implementation of school-based nursing programs for children with special health care needs: a scoping review protocol. 有特殊卫生保健需要的儿童的校本护理方案的结构和实施:范围审查方案。
IF 4.5 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-27 DOI: 10.11124/JBIES-25-00156
Sarah Keeping, Simonne Collins, Leah Boulos, Audrey Steenbeek, Janet Curran

Objective: The objective of this scoping review is to identify how school-based nursing programs that support children with special health care needs (CSHCN) are structured and implemented globally.

Introduction: The number of CSHCN living and participating in the community is increasing due to medical and technological advances. To participate fully in school, CSHCN may require support for a wide range of health conditions. There is minimal research that synthesizes the development and implementation of school-based nursing programs and interventions, particularly in Canada.

Eligibility criteria: Academic and gray literature will be considered for inclusion. Included sources must refer to school-aged children (pre-primary through 12) and discuss a school-based nursing program or intervention that targets medical or health needs. Literature reviews will be excluded from this review; however, their reference lists will be scanned for relevant studies. There are no restrictions on geographical location or date of publication, but only studies published in English will be considered for inclusion.

Methods: This scoping review will be conducted using the JBI methodology for scoping reviews. A search strategy has been developed using the Population, Concept, Context (PCC) mnemonic. The search has been developed in MEDLINE (Ovid) and will be translated to Embase, CINAHL, and Scopus, and reported in a Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). The Reach, Effectiveness, Adoption, Implementation, and Maintenance Framework (RE-AIM) will be used to categorize the range of implementation strategies across included studies. Findings related to determinants (facilitators and barriers) will be organized according to the Consolidated Framework for Implementation Research.

Review registration: OSF.

目的:本范围综述的目的是确定如何在全球范围内组织和实施以学校为基础的支持有特殊卫生保健需求的儿童的护理计划。由于医疗和技术的进步,生活和参与社区的CSHCN人数正在增加。为了充分参与学校活动,CSHCN可能需要对各种健康状况提供支持。综合学校护理计划和干预措施的发展和实施的研究很少,特别是在加拿大。资格标准:学术和灰色文献将被考虑纳入。纳入的资料必须涉及学龄儿童(从学龄前到12岁),并讨论以学校为基础的护理计划或针对医疗或健康需求的干预措施。文献综述将被排除在本综述之外;但是,他们的参考文献列表将被扫描以查找相关研究。没有地理位置或出版日期的限制,但只有用英语发表的研究才会被考虑纳入。方法:本次范围审查将使用JBI方法进行范围审查。使用人口、概念、上下文(PCC)助记符开发了一种搜索策略。该搜索已在MEDLINE (Ovid)中开发,并将被翻译为Embase, CINAHL和Scopus,并在scope - Reviews的首选报告项目和meta -分析扩展(PRISMA-ScR)中报告。Reach、有效性、采用、实施和维护框架(RE-AIM)将用于对纳入研究的实施策略范围进行分类。与决定因素(促进因素和障碍)有关的调查结果将根据实施研究综合框架进行整理。审核注册:OSF。
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引用次数: 0
Barriers and facilitators for the adoption of digital technologies for tuberculosis medication adherence: a qualitative systematic review protocol. 结核病药物依从性采用数字技术的障碍和促进因素:一项定性系统审查方案。
IF 4.5 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-27 DOI: 10.11124/JBIES-25-00054
Zipporah Dery, Celso Pagatpatan, Margel Bonifacio

Objective: This qualitative systematic review will aim to explore the barriers and facilitators of the use of digital adherence technologies for tuberculosis treatment. The review will focus on the human factors that support the use of these technologies in tuberculosis treatment.

Introduction: More than 10 million people are infected with tuberculosis every year. Failure to adhere to the treatment regimen is the key reason for the disease's continuing burden worldwide. Numerous efforts have been made to address non-adherence to treatment, including the use of digital adherence technologies. However, recent studies on such technologies show conflicting findings about their effectiveness.

Eligibility criteria: This review will consider studies reporting on patients and health care workers and the use of digital tools for tuberculosis treatment adherence. The review will include studies that focus on drug-sensitive tuberculosis, drug-resistant tuberculosis, and latent tuberculosis infection, as well as studies on patients with tuberculosis and common comorbidities, such as diabetes or human immunodeficiency virus.

Methods: This review will follow the JBI methodology for qualitative systematic reviews. PubMed, Embase (Ovid), Scopus, and Emcare (Ovid) will be searched for published studies. Searches will also be conducted for gray literature. Two reviewers will independently conduct study selection, critical appraisal, data extraction, and data synthesis. The ConQual approach will be used to assess confidence in the findings of the meta-aggregated data. There will be no date or language limitations.

Review registration: PROSPERO CRD42025645171.

目的:本定性系统综述旨在探讨在结核病治疗中使用数字依从性技术的障碍和促进因素。审查将侧重于支持在结核病治疗中使用这些技术的人为因素。导言:每年有1000多万人感染结核病。未能坚持治疗方案是该疾病在世界范围内继续造成负担的关键原因。已经做出了许多努力来解决不坚持治疗的问题,包括使用数字坚持治疗技术。然而,最近对这些技术的研究表明,它们的有效性存在矛盾。资格标准:本综述将考虑报告患者和卫生保健工作者以及使用数字工具促进结核病治疗依从性的研究。该审查将包括侧重于药物敏感结核病、耐药结核病和潜伏性结核病感染的研究,以及对结核病和常见合并症(如糖尿病或人类免疫缺陷病毒)患者的研究。方法:本综述将遵循JBI方法进行定性系统评价。PubMed, Embase (Ovid), Scopus和Emcare (Ovid)将搜索已发表的研究。灰色文献也将进行搜索。两名审稿人将独立进行研究选择、批判性评估、数据提取和数据合成。将使用征服方法来评估对元汇总数据结果的信心。没有日期和语言限制。审核注册:PROSPERO CRD42025645171。
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引用次数: 0
Evaluating the proper use of weighted mean difference in evidence synthesis: a meta-epidemiology study. 评价证据合成中加权平均差的正确使用:一项荟萃流行病学研究。
IF 4.5 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-27 DOI: 10.11124/JBIES-25-00520
Xing Xing, Yining Wang, Jiayi Tong, Lifeng Lin

Introduction: The weighted mean difference (WMD) has long been used in evidence syntheses involving continuous outcomes. However, it is sometimes applied interchangeably with the mean difference (MD) despite their conceptual distinction: the WMD is intended solely for pooled estimates across studies, not for individual study results. Misuse of WMD can lead to ambiguity in reporting and interpretation, yet empirical evidence on their prevalence and patterns in published systematic reviews and meta-analyses (SRMAs) remains limited.

Methods: We conducted a meta-epidemiological study of SRMAs reporting continuous outcomes, published in The BMJ during 2 periods: 2002-2007 and 2020-2025. Each article was evaluated to determine whether the WMD was reported, whether its use was appropriate, and the rationale for each assessment. Two authors independently performed the evaluations, and any disagreements were resolved through discussion.

Results: In the earlier study period, misuse of the term WMD was widespread, with many SRMAs employing it interchangeably with the MD without clear justification. Over time, the frequency of such misuse decreased, coinciding with the broader adoption of reporting guidelines and increased methodological rigor. Nonetheless, inappropriate applications of WMD persist in more recent publications.

Conclusions: Persistent inconsistencies in WMD use reveal gaps in methodological understanding and reporting practice. Ongoing efforts to refine guidance and promote evidence synthesis literacy are essential to improve the rigor and transparency of SRMAs.

长期以来,加权平均差(WMD)一直被用于涉及连续结果的证据合成。然而,尽管它们在概念上有所区别,但有时它与平均差值(MD)互换使用:平均差值仅用于跨研究的汇总估计,而不是用于单个研究结果。滥用大规模杀伤性武器可能导致报告和解释的模糊性,但在已发表的系统评价和荟萃分析(srma)中,关于其流行程度和模式的经验证据仍然有限。方法:我们对报告连续结果的srma进行了荟萃流行病学研究,并在2002-2007年和2020-2025年两个时期发表在《英国医学杂志》上。对每篇文章进行了评估,以确定是否报告了大规模杀伤性武器,其使用是否适当,以及每次评估的理由。两位作者独立进行评估,任何分歧都通过讨论解决。结果:在早期研究阶段,大规模杀伤性武器一词的误用很普遍,许多srma在没有明确理由的情况下将其与大规模杀伤性武器交替使用。随着时间的推移,这种滥用的频率减少了,这与广泛采用报告准则和提高方法的严谨性相一致。尽管如此,在最近的出版物中,大规模杀伤性武器的不当应用仍然存在。结论:大规模杀伤性武器使用的持续不一致揭示了方法学理解和报告实践方面的差距。不断完善指南和促进证据综合素养的努力对于提高srma的严谨性和透明度至关重要。
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引用次数: 0
Prognostic significance of the dysplastic margin for predicting recurrence and survival in patients with primary oral squamous cell carcinoma resected with curative intent: a systematic review protocol. 以治疗为目的切除的原发性口腔鳞状细胞癌患者的增生异常边缘预测复发和生存的预后意义:一项系统回顾方案。
IF 4.5 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-21 DOI: 10.11124/JBIES-24-00510
Belinda Liu, Gary Brierly, Omar Breik, Matthew Stephenson

Objective: The objective of this review is to evaluate whether the presence and severity of the dysplastic margin predicts recurrence or survival outcomes in patients with primary oral squamous cell carcinoma (OSCC) resected with curative intent.

Introduction: There is variable evidence whether a dysplastic OSCC margin predicts worse recurrence or survival outcomes and, therefore, no consensus on whether a dysplastic margin should be regarded as an involved margin. Ambiguity of the prognostic significance of dysplasia in the resection margin means that management is institutionally dependent.

Inclusion criteria: This systematic review will include studies of patients with primary OSCC who have undergone surgery with curative intent, with or without adjuvant treatment. Studies will be included if they compare the recurrence and survival outcomes of dysplastic margins compared with clear, close, or involved margins.

Methods: PubMed, Embase (Ovid), Web of Science Core Collection, Scopus, and gray literature will be searched. Two reviewers will independently undertake title/abstract and full-text screening. Included studies will be critically appraised using the QUIPS tool. Data extraction will use the CHARMS-PF checklist. Odds ratio, risk ratios, and hazard ratios along with standard errors, variances, or CIs will be extracted. Where possible, hazard ratios will be computed if not directly reported. Separate meta-analyses will be done for odds ratios, univariate hazard ratios, and multivariate hazard ratios. If meta-analysis is not possible, data will be synthesized narratively. The certainty of evidence will be assessed using the GRADE approach, and a Summary of Findings will be presented.

Review registration: PROSPERO CRD42024604073.

目的:本综述的目的是评估增生异常边缘的存在和严重程度是否可以预测原发口腔鳞状细胞癌(OSCC)患者的复发或生存结果。有不同的证据表明,异常增生的OSCC切缘是否预示着更糟糕的复发或生存结果,因此,对于是否应将异常增生的切缘视为相关切缘,尚无共识。不明确的预后意义的不典型增生在切除边缘意味着管理是制度上的依赖。纳入标准:本系统综述将包括接受手术治疗的原发性OSCC患者,不论是否进行辅助治疗。如果研究将发育不良边缘与清晰、闭合或累及边缘的复发和生存结果进行比较,则将纳入研究。方法:检索PubMed、Embase (Ovid)、Web of Science Core Collection、Scopus和灰色文献。两名审稿人将独立进行标题/摘要和全文筛选。纳入的研究将使用QUIPS工具进行严格评估。数据提取将使用CHARMS-PF检查表。将提取优势比、风险比、风险比以及标准误差、方差或ci。在可能的情况下,如果没有直接报告,将计算风险比。将分别对优势比、单因素风险比和多因素风险比进行meta分析。如果荟萃分析不可能,数据将以叙述的方式合成。将使用GRADE方法评估证据的确定性,并提交一份结论摘要。评审注册号:PROSPERO CRD42024604073。
{"title":"Prognostic significance of the dysplastic margin for predicting recurrence and survival in patients with primary oral squamous cell carcinoma resected with curative intent: a systematic review protocol.","authors":"Belinda Liu, Gary Brierly, Omar Breik, Matthew Stephenson","doi":"10.11124/JBIES-24-00510","DOIUrl":"https://doi.org/10.11124/JBIES-24-00510","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this review is to evaluate whether the presence and severity of the dysplastic margin predicts recurrence or survival outcomes in patients with primary oral squamous cell carcinoma (OSCC) resected with curative intent.</p><p><strong>Introduction: </strong>There is variable evidence whether a dysplastic OSCC margin predicts worse recurrence or survival outcomes and, therefore, no consensus on whether a dysplastic margin should be regarded as an involved margin. Ambiguity of the prognostic significance of dysplasia in the resection margin means that management is institutionally dependent.</p><p><strong>Inclusion criteria: </strong>This systematic review will include studies of patients with primary OSCC who have undergone surgery with curative intent, with or without adjuvant treatment. Studies will be included if they compare the recurrence and survival outcomes of dysplastic margins compared with clear, close, or involved margins.</p><p><strong>Methods: </strong>PubMed, Embase (Ovid), Web of Science Core Collection, Scopus, and gray literature will be searched. Two reviewers will independently undertake title/abstract and full-text screening. Included studies will be critically appraised using the QUIPS tool. Data extraction will use the CHARMS-PF checklist. Odds ratio, risk ratios, and hazard ratios along with standard errors, variances, or CIs will be extracted. Where possible, hazard ratios will be computed if not directly reported. Separate meta-analyses will be done for odds ratios, univariate hazard ratios, and multivariate hazard ratios. If meta-analysis is not possible, data will be synthesized narratively. The certainty of evidence will be assessed using the GRADE approach, and a Summary of Findings will be presented.</p><p><strong>Review registration: </strong>PROSPERO CRD42024604073.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146012529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of available datasets for public mental health surveillance in Australia and evaluation of the National Mental Health and Suicide Prevention Agreement: scoping review protocol. 澳大利亚公共精神卫生监测现有数据集的特点和对《国家精神卫生和预防自杀协定:范围审查议定书》的评价。
IF 4.5 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-21 DOI: 10.11124/JBIES-25-00122
Hiroko Fujimoto, Narendar Manohar, Samuel B Harvey, Peter A Baldwin

Objective: This scoping review will identify and describe available datasets collected nationally to measure public mental health in Australia. The review will also identify gaps in current data collection by mapping the identified datasets to the priorities of the National Mental Health and Suicide Prevention Agreement (2022).

Introduction: Australia's public mental health data collection has been fragmented by multiple initiatives and jurisdictional inconsistency. Data largely focus on service input and activity, ignoring other factors such as social determinants, prevention, and early intervention. To effectively assess and monitor Australia's mental health, researchers and policymakers need data that are consistent, inclusive, appropriate, and holistic.

Eligibility criteria: This scoping review focuses on Australian national data for public mental health surveillance, encompassing mental health promotion, symptoms, disorders, services, workforce, and prevention. Mental health conditions outside DSM-5 or ICD-11 will be excluded.

Methods: The review will be conducted in accordance with the JBI methodology for scoping reviews and Godin's gray literature search methods. The search strategy will involve hand-searching target websites. Language and region will be limited to English and Australia. Publication date will not be restricted. Search results, dataset selection, and data extraction will be recorded in an Excel spreadsheet. Two rounds of screening will be conducted to finalize selection. Data will be extracted using an extraction table developed by the reviewers based on JBI methodology. Extracted data will be categorized into meaningful groups to answer the review questions. Data will be presented in tables and/or diagrams, accompanied by narrative summary.

Review registration: OSF https://osf.io/sa756.

目的:本范围审查将确定和描述在全国范围内收集的可用数据集,以衡量澳大利亚的公共心理健康。审查还将通过将已确定的数据集与《国家精神卫生和预防自杀协定》(2022年)的优先事项相对应,确定当前数据收集方面的差距。导言:澳大利亚的公共心理健康数据收集因多种举措和管辖权不一致而支离破碎。数据主要集中在服务投入和活动上,而忽略了其他因素,如社会决定因素、预防和早期干预。为了有效地评估和监测澳大利亚的心理健康,研究人员和政策制定者需要一致、包容、适当和全面的数据。资格标准:本次范围审查的重点是澳大利亚公共心理健康监测的国家数据,包括心理健康促进、症状、障碍、服务、劳动力和预防。DSM-5或ICD-11之外的精神健康状况将被排除在外。方法:按照JBI范围综述方法和Godin灰色文献检索方法进行综述。搜索策略包括手动搜索目标网站。语言和地区将仅限于英语和澳大利亚。出版日期不受限制。搜索结果、数据集选择和数据提取将记录在Excel电子表格中。将进行两轮筛选以最终确定。数据将使用由审稿人基于JBI方法开发的提取表进行提取。提取的数据将被分类为有意义的组来回答复习问题。数据将以表格和/或图表的形式呈现,并附有叙述性摘要。评审注册:OSF https://osf.io/sa756。
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引用次数: 0
Effectiveness of support interventions for improving well-being outcomes in parents of preterm infants: an umbrella review protocol. 改善早产儿父母福祉结果的支持干预措施的有效性:一项总括性审查方案。
IF 4.5 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-21 DOI: 10.11124/JBIES-25-00324
Tippawan Srichalerm, Ratchanok Phonyiam, Donruedee Kamkhoad

Objective: This umbrella review will aim to assess the effectiveness of support interventions for improving well-being outcomes in parents of preterm infants.

Introduction: Preterm birth presents significant emotional, psychological, and social challenges for parents, often adversely affecting their well-being. Numerous systematic reviews have examined support interventions aimed at improving parental outcomes. An umbrella review is warranted to synthesize and critically appraise this diverse evidence. Such a review could guide health care professionals in implementing effective, evidence-based strategies to support parents throughout the parenthood journey of preterm infants.

Eligibility criteria: This umbrella review will include systematic reviews that examine the effectiveness of support interventions designed to enhance the well-being of parents of preterm infants. All types of support interventions will be considered, regardless of the parents' gender or age, the infants' gestational age, or the contextual setting.

Methods: This review will follow the JBI methodology for umbrella reviews. A comprehensive search will be conducted across PubMed, the Cochrane Database of Systematic Reviews, CINAHL (EBSCOhost), Embase (Embase.com), Scopus, Open Access Theses and Dissertations (OATD), and the Mahidol Library Catalog (OPAC) to identify relevant reviews. There will be no date or language limitations. Two reviewers will independently screen titles, abstracts, and full texts using predefined eligibility criteria. The methodological quality of the included reviews will be assessed using the JBI checklist for systematic reviews and research syntheses. Data will be extracted using a piloted, adapted JBI tool. Findings will be presented in tables with narrative summaries, visual aids, and a citation matrix to assess study overlap.

Review registration: PROSPERO CRD420251071668.

目的:本综述旨在评估支持干预对改善早产儿父母幸福感结果的有效性。前言:早产给父母带来了重大的情感、心理和社会挑战,往往对他们的健康产生不利影响。许多系统的回顾研究了旨在改善父母结果的支持干预措施。有必要对这些不同的证据进行综合和批判性评价。这样的审查可以指导卫生保健专业人员实施有效的、以证据为基础的战略,在早产儿的整个为人父母过程中为父母提供支持。资格标准:这项总括性审查将包括系统审查旨在提高早产儿父母福祉的支持干预措施的有效性。所有类型的支持干预将被考虑,无论父母的性别或年龄,婴儿的胎龄,或背景设置。方法:本综述将遵循JBI方法进行总括性综述。将在PubMed、Cochrane系统综述数据库、CINAHL (EBSCOhost)、Embase (Embase.com)、Scopus、开放获取论文(OATD)和Mahidol图书馆目录(OPAC)上进行全面搜索,以确定相关综述。没有日期和语言限制。两名审稿人将使用预定义的资格标准独立筛选标题、摘要和全文。纳入综述的方法学质量将使用JBI检查表进行系统综述和研究综合评估。数据将使用试点的、经过调整的JBI工具提取。研究结果将以表格形式呈现,并附有叙述性摘要、视觉辅助工具和引文矩阵,以评估研究重叠。审核注册号:PROSPERO CRD420251071668。
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引用次数: 0
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JBI evidence synthesis
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