Pub Date : 2007-04-23DOI: 10.1109/NEMS.2007.352097
T. Thiwawong, B. Tunhoo, J. Nukeaw
Zinc selenide (ZnSe)/copper-phthalocyanine (CuPc) hybrid thin films were prepared by electron beam evaporator on glass substrate from %weight mixed of ZnSe:CuPc powders. The film thickness was 500 nm. The substrate temperatures were varied at room temperature to 150degC. X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM) were used to characterize the crystalline structure and morphology of deposited hybrid thin films. XRD patterns show two peaks of the orientation of (200) plane monoclinic structure in CuPc material and (111) plane cubic structure in ZnSe material. The FE-SEM image of hybrid thin film deposited with substrate temperature at 150degC seems to have the nanocrystalline-ZnSe formed on nanorod-like CuPc.
{"title":"Crystalline Structure and Morphology of ZnSe/CuPc Hybrid Thin Film prepared by Electron Beam Evaporator","authors":"T. Thiwawong, B. Tunhoo, J. Nukeaw","doi":"10.1109/NEMS.2007.352097","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352097","url":null,"abstract":"Zinc selenide (ZnSe)/copper-phthalocyanine (CuPc) hybrid thin films were prepared by electron beam evaporator on glass substrate from %weight mixed of ZnSe:CuPc powders. The film thickness was 500 nm. The substrate temperatures were varied at room temperature to 150degC. X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM) were used to characterize the crystalline structure and morphology of deposited hybrid thin films. XRD patterns show two peaks of the orientation of (200) plane monoclinic structure in CuPc material and (111) plane cubic structure in ZnSe material. The FE-SEM image of hybrid thin film deposited with substrate temperature at 150degC seems to have the nanocrystalline-ZnSe formed on nanorod-like CuPc.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"150 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123216394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-23DOI: 10.1109/NEMS.2007.352094
S. Yu, T. T. Anh, Y. Ihm, Dojin Kim, Hyojin Kim, Soon-Ku Hong, Chang Soo Kim, H. Ryu
Amorphous Ge1-x Mnx thin films grown by low temperature vapor deposition were annealed and their electrical and magnetic properties have been studied. Amorphous Ge1-xMnx thin films were annealed at 300°C, 400°C, 500°C, 600°C and 700°C for 3 minutes in high vacuum chamber. X-ray diffraction and TEM analyses reveal that as-grown Ge1-xMnx thin films are amorphous, and fine crystalline phases are precipitated when annealed. The fine crystalline precipitates appear at the lower temperature as the Mn concentration of amorphous Ge1-x Mnx thin films increases. As-grown amorphous Ge1-x Mnx thin films have p-type majority carriers and the type of majority carriers is not changed after annealing, but the electrical resistivity increases with annealing temperature. Magnetization characteristics show that the as-grown amorphous Ge1-x Mnx thin films are ferromagnetic and the Curie temperatures are around 130K. Curie temperature and saturation magnetization of annealed Ge1-x Mnx thin films increase with annealing temperature. There are different mechanisms to understand increasing of Curie temperature that is related with annealing temperature. Firstly, interaction between Mn spins might be changed by annealing effect. Secondly, magnetization behavior and X-ray analysis imply that the formation of ferromagnetic Ge3Mn5 phase causes the change of magnetic and electrical properties of annealed Ge1-x Mnx thin films.
{"title":"Magnetic and Magnetotransport Properties of Annealed Amorphous Ge1-xMnx Semiconductor Thin Films","authors":"S. Yu, T. T. Anh, Y. Ihm, Dojin Kim, Hyojin Kim, Soon-Ku Hong, Chang Soo Kim, H. Ryu","doi":"10.1109/NEMS.2007.352094","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352094","url":null,"abstract":"Amorphous Ge<sub>1-x </sub>Mn<sub>x</sub> thin films grown by low temperature vapor deposition were annealed and their electrical and magnetic properties have been studied. Amorphous Ge<sub>1-x</sub>Mn<sub>x</sub> thin films were annealed at 300°C, 400°C, 500°C, 600°C and 700°C for 3 minutes in high vacuum chamber. X-ray diffraction and TEM analyses reveal that as-grown Ge<sub>1-x</sub>Mn<sub>x</sub> thin films are amorphous, and fine crystalline phases are precipitated when annealed. The fine crystalline precipitates appear at the lower temperature as the Mn concentration of amorphous Ge<sub>1-x </sub>Mn<sub>x</sub> thin films increases. As-grown amorphous Ge<sub>1-x </sub>Mn<sub>x</sub> thin films have p-type majority carriers and the type of majority carriers is not changed after annealing, but the electrical resistivity increases with annealing temperature. Magnetization characteristics show that the as-grown amorphous Ge<sub>1-x </sub>Mn<sub>x</sub> thin films are ferromagnetic and the Curie temperatures are around 130K. Curie temperature and saturation magnetization of annealed Ge<sub>1-x </sub>Mn<sub>x</sub> thin films increase with annealing temperature. There are different mechanisms to understand increasing of Curie temperature that is related with annealing temperature. Firstly, interaction between Mn spins might be changed by annealing effect. Secondly, magnetization behavior and X-ray analysis imply that the formation of ferromagnetic Ge<sub>3</sub>Mn<sub>5</sub> phase causes the change of magnetic and electrical properties of annealed Ge<sub>1-x </sub>Mn<sub>x</sub> thin films.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121684555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-23DOI: 10.1109/NEMS.2007.352086
Chili-Ming Sun, Chuanwei Wang, W. Fang
This study presents a novel dual-axis CMOS MEMS scanning stage driven using the Lorentz force. The device has been successfully implemented using the TSMC 2P4M process. The current routing achieved by three metal layers enables the independent driving for each axis. The measurement results show that the device has resonant frequencies of 1.36KHz and 2.26KHz respectively for each axis.
{"title":"CMOS MEMS Lorentz Force Dual-axis Scanning-Stage","authors":"Chili-Ming Sun, Chuanwei Wang, W. Fang","doi":"10.1109/NEMS.2007.352086","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352086","url":null,"abstract":"This study presents a novel dual-axis CMOS MEMS scanning stage driven using the Lorentz force. The device has been successfully implemented using the TSMC 2P4M process. The current routing achieved by three metal layers enables the independent driving for each axis. The measurement results show that the device has resonant frequencies of 1.36KHz and 2.26KHz respectively for each axis.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128042385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-23DOI: 10.1109/NEMS.2007.352111
K. Ha, I. Yi, G. Nisola, W. Chung, Jaewan Kim, Y.J. Choi, C. Kang, Yong-Sang Kim
A capillary electrophoresis (CE) microchip with an amperometric, electrochemical detector (ECD) was developed to detect notorious environmental hormones, bisphenol A (BPA) and butyl-phenol. We developed a CE/ECD microchip which separates and detects the target analytes. Prussian blue (PB), an electrocatalyst that assists in detecting the analytes effectively, was used to modify the working electrode indium tin oxide (ITO) by the electrodeposition process. Each compound is transported by CE to the working electrode at different flow rates according to their charges and masses. Compared to the bare ITO electrode, the PB/ITO electrode is beneficial in terms of improved analytical performance, that is, enhanced sensitivity, low cost requirement, and simple construction scheme. The CE/ECD microchip with PB/ITO electrode is a promising technology for the easy detection of certain environmental hormones.
{"title":"Development of a Capillary Electrophoresis Microchip Format Electrochemical Detector for the Sensing of Endocrine Disruptors","authors":"K. Ha, I. Yi, G. Nisola, W. Chung, Jaewan Kim, Y.J. Choi, C. Kang, Yong-Sang Kim","doi":"10.1109/NEMS.2007.352111","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352111","url":null,"abstract":"A capillary electrophoresis (CE) microchip with an amperometric, electrochemical detector (ECD) was developed to detect notorious environmental hormones, bisphenol A (BPA) and butyl-phenol. We developed a CE/ECD microchip which separates and detects the target analytes. Prussian blue (PB), an electrocatalyst that assists in detecting the analytes effectively, was used to modify the working electrode indium tin oxide (ITO) by the electrodeposition process. Each compound is transported by CE to the working electrode at different flow rates according to their charges and masses. Compared to the bare ITO electrode, the PB/ITO electrode is beneficial in terms of improved analytical performance, that is, enhanced sensitivity, low cost requirement, and simple construction scheme. The CE/ECD microchip with PB/ITO electrode is a promising technology for the easy detection of certain environmental hormones.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115960216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-23DOI: 10.1109/NEMS.2007.352092
T. Leu, Hung‐Ying Chen, F. Hsiao
Dielectrophoretic (DEP) flow sorters for continuously selecting particles (cells) of interest from a mixture of many samples were designed and studied. DEP forces created by non-uniform electric fields are used as confining forces to three-dimensionally focus bio-particles into a single particle stream, as well as deflection forces to continuously sort the bio-particles in the micro sorter. The key mechanism of the flow sorters that can focus and sort particles against fluid flows is demonstrated numerically and experimentally.
{"title":"Micro Sorters with 3D Focusing and Continuous Sorting","authors":"T. Leu, Hung‐Ying Chen, F. Hsiao","doi":"10.1109/NEMS.2007.352092","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352092","url":null,"abstract":"Dielectrophoretic (DEP) flow sorters for continuously selecting particles (cells) of interest from a mixture of many samples were designed and studied. DEP forces created by non-uniform electric fields are used as confining forces to three-dimensionally focus bio-particles into a single particle stream, as well as deflection forces to continuously sort the bio-particles in the micro sorter. The key mechanism of the flow sorters that can focus and sort particles against fluid flows is demonstrated numerically and experimentally.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"129 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132079291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-23DOI: 10.1109/NEMS.2007.352182
Jen-Hung Wei, W. Hsu, S. Fan
Droplet heating and pumping were performed on a versatile microelectrode by selectively applying appropriate electric signals. The designed electrode is in a meander-line shape and covered by an insulator. On the one hand, when a potential difference is applied along the electrode, power dissipated by the resistance of the electrode causes droplet heating. On the other hand, when an electric field exists across the insulator above the electrode, the charges stored in the capacitor alter the surface wettability and pump droplet. Manipulated droplets were placed between parallel plates with passivated versatile microelectrodes on the bottom plate and a Teflon-coated blank ITO on the top plate. We successfully applied a DC voltage at the two terminals of the meander-line electrode to heat up the electrode as well as the droplet above. Besides, pumping droplets by EWOD was demonstrated by applying a proper AC voltage between the electrode on the bottom plate and the ITO on the top plate. With the proposed versatile microelectrode design and actuation scheme, heating and EWOD were obtained on an identical electrode. A digital microfluidic chip capable of droplet manipulation by EWOD and droplet heating was presented.
{"title":"Realizing Temperature-Controlled Digital Microfluidic Chips with Versatile Microelectrodes","authors":"Jen-Hung Wei, W. Hsu, S. Fan","doi":"10.1109/NEMS.2007.352182","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352182","url":null,"abstract":"Droplet heating and pumping were performed on a versatile microelectrode by selectively applying appropriate electric signals. The designed electrode is in a meander-line shape and covered by an insulator. On the one hand, when a potential difference is applied along the electrode, power dissipated by the resistance of the electrode causes droplet heating. On the other hand, when an electric field exists across the insulator above the electrode, the charges stored in the capacitor alter the surface wettability and pump droplet. Manipulated droplets were placed between parallel plates with passivated versatile microelectrodes on the bottom plate and a Teflon-coated blank ITO on the top plate. We successfully applied a DC voltage at the two terminals of the meander-line electrode to heat up the electrode as well as the droplet above. Besides, pumping droplets by EWOD was demonstrated by applying a proper AC voltage between the electrode on the bottom plate and the ITO on the top plate. With the proposed versatile microelectrode design and actuation scheme, heating and EWOD were obtained on an identical electrode. A digital microfluidic chip capable of droplet manipulation by EWOD and droplet heating was presented.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131749014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-23DOI: 10.1109/NEMS.2007.352102
Li-jun Dai, Yujun Zhang, H. Zhou, Lei Li, Hongwei Duan
The ionomer of sulfonated ethylene vinyl alcohol copolymers (EVOH-SO3K) crosslinked by toluene-2,4-diisocyanate (EVOH-SO3K) was synthesized and ionic polymer-metal composites (IPMC) based on EVOH-SO3K was produced through electroless deposition of argentum onto the surfaces of EVOH-SO3K membrane. FTIR spectroscopy confirmed sulfonic modification by introduction of two characteristic peaks at 1264cm-1 (asymmetric stretching vibration) and 1022cm-1 (symmetric stretching vibration) of the S=O stretch vibration in the SO3-group respectively; and the crosslinking modification through introduction of the bands at 1190cm-1 which is attributed to the C-O-C stretching vibration of amidation between -OH and toluene-2,4-diisocyanate(TDI); scanning electron microscopy (SEM) showed the electrode based on argentum is deposited uniformly on the surface of ionomer. Performance tests showed IPMC with the surface resistance of 0.8Omega/mm2 could be deformed under 3V applied voltage through three time chemical deposition, and the deformation angle could reach to 36deg.
{"title":"Preparation of a New Ionic Polymer-metal Composite","authors":"Li-jun Dai, Yujun Zhang, H. Zhou, Lei Li, Hongwei Duan","doi":"10.1109/NEMS.2007.352102","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352102","url":null,"abstract":"The ionomer of sulfonated ethylene vinyl alcohol copolymers (EVOH-SO3K) crosslinked by toluene-2,4-diisocyanate (EVOH-SO3K) was synthesized and ionic polymer-metal composites (IPMC) based on EVOH-SO3K was produced through electroless deposition of argentum onto the surfaces of EVOH-SO3K membrane. FTIR spectroscopy confirmed sulfonic modification by introduction of two characteristic peaks at 1264cm-1 (asymmetric stretching vibration) and 1022cm-1 (symmetric stretching vibration) of the S=O stretch vibration in the SO3-group respectively; and the crosslinking modification through introduction of the bands at 1190cm-1 which is attributed to the C-O-C stretching vibration of amidation between -OH and toluene-2,4-diisocyanate(TDI); scanning electron microscopy (SEM) showed the electrode based on argentum is deposited uniformly on the surface of ionomer. Performance tests showed IPMC with the surface resistance of 0.8Omega/mm2 could be deformed under 3V applied voltage through three time chemical deposition, and the deformation angle could reach to 36deg.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132601521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-23DOI: 10.1109/NEMS.2007.352085
K. W. Chae, K. Koh, Soonil Lee
Cold cathodes which can emit high currents were fabricated using carbon nanofiber (CNF) films synthesized via hot-filament chemical vapor deposition (HFCVD) method. The synthesis of CNF films with good electron-emitting characteristics relied on the judicial choice of metal catalysts. As it turned out electroplated nickel catalysts on gold buffer layers was suitable for the synthesis of CNFs with many protrusions which contributed to the good electron emission. Thickness and uniformity of nickel layers decided emission properties of CNF films. The substrate temperatures during the HFCVD process also were key factors determining the emission characteristics of CNF films. We took advantage of the simplicity and large-area compatibility of electroplating to fabricate large area patterned cathodes which can generate emission currents of sufficient magnitude for various applications.
{"title":"Fabrication of High Current Emitting Cold Cathodes Based on Carbon Nanofiber Films Synthesized Using Electroplated Nickel Catalyst","authors":"K. W. Chae, K. Koh, Soonil Lee","doi":"10.1109/NEMS.2007.352085","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352085","url":null,"abstract":"Cold cathodes which can emit high currents were fabricated using carbon nanofiber (CNF) films synthesized via hot-filament chemical vapor deposition (HFCVD) method. The synthesis of CNF films with good electron-emitting characteristics relied on the judicial choice of metal catalysts. As it turned out electroplated nickel catalysts on gold buffer layers was suitable for the synthesis of CNFs with many protrusions which contributed to the good electron emission. Thickness and uniformity of nickel layers decided emission properties of CNF films. The substrate temperatures during the HFCVD process also were key factors determining the emission characteristics of CNF films. We took advantage of the simplicity and large-area compatibility of electroplating to fabricate large area patterned cathodes which can generate emission currents of sufficient magnitude for various applications.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132953031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-23DOI: 10.1109/NEMS.2007.352153
J. Yim, Jong Taek Kim, Soonil Lee, F. Rotermund, K. Koh
HiPco and Arc-made single-walled carbon nanotubes (SWCNTs) were incorporated into silica matrices via a conventional sol-gel method to form SWCNTs/silica composites. Optical absorption and FT-Raman spectroscopy revealed that purification process using acid treatment resulted in preferential removal of metallic SWCNTs and severe damage and/or side-wall functionalization of HiPco SWCNTs. Z-scan measurements of SWCNTs/silica composites showed self-defocusing and bleached absorption phenomena which indicated that both the real and imaginary parts of X3, the third-order nonlinear optical susceptibility, of these composites had negative sign.
{"title":"Nonlinear Optical Properties of SWCNTs Incorporated Silica Composites","authors":"J. Yim, Jong Taek Kim, Soonil Lee, F. Rotermund, K. Koh","doi":"10.1109/NEMS.2007.352153","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352153","url":null,"abstract":"HiPco and Arc-made single-walled carbon nanotubes (SWCNTs) were incorporated into silica matrices via a conventional sol-gel method to form SWCNTs/silica composites. Optical absorption and FT-Raman spectroscopy revealed that purification process using acid treatment resulted in preferential removal of metallic SWCNTs and severe damage and/or side-wall functionalization of HiPco SWCNTs. Z-scan measurements of SWCNTs/silica composites showed self-defocusing and bleached absorption phenomena which indicated that both the real and imaginary parts of X3, the third-order nonlinear optical susceptibility, of these composites had negative sign.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132453010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-23DOI: 10.1109/NEMS.2007.352191
U. Sakulkhu, S. Jarupaiboon, A. Trithong, S. Prathontep, V. Janyaprasert, S. Puttipipatkhachorn, U. Ruktanonchai
Solid lipid nanoparticles (SLNs) recently gain attention as colloidal drug carriers, for both intravenous and dermal delivery. The present study focused on the preparation and some characterization of SLN associated with gamma-oryzanol of the specialized delivery systems. The nanoparticles, containing Dynasan 114 as lipid and Pluronicreg F68 as emulsifying agent were prepared by hot homogenization method. Particle sizes of SLNs were in suitable range and homogenous. Moreover, SLNs containing gamma-oryzanol are stable for investigated time as suggested by size, pH, % entrapment efficiency and DSC. Moreover, HPLC chromatograms indicated that no degradation was observed within the investigated period. Therefore chosen composition and method of preparation benefit the stability of the nanoparticles, which is suitable for transdermal skin penetration.
{"title":"Production and Characterization of Rice bran extract encapsulated in Solid Lipid Nanoparticles for Dermal Delivery","authors":"U. Sakulkhu, S. Jarupaiboon, A. Trithong, S. Prathontep, V. Janyaprasert, S. Puttipipatkhachorn, U. Ruktanonchai","doi":"10.1109/NEMS.2007.352191","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352191","url":null,"abstract":"Solid lipid nanoparticles (SLNs) recently gain attention as colloidal drug carriers, for both intravenous and dermal delivery. The present study focused on the preparation and some characterization of SLN associated with gamma-oryzanol of the specialized delivery systems. The nanoparticles, containing Dynasan 114 as lipid and Pluronicreg F68 as emulsifying agent were prepared by hot homogenization method. Particle sizes of SLNs were in suitable range and homogenous. Moreover, SLNs containing gamma-oryzanol are stable for investigated time as suggested by size, pH, % entrapment efficiency and DSC. Moreover, HPLC chromatograms indicated that no degradation was observed within the investigated period. Therefore chosen composition and method of preparation benefit the stability of the nanoparticles, which is suitable for transdermal skin penetration.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131439774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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