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2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems最新文献

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Nanostructured Silicon Carbide Molds for Glass Press Molding 玻璃压制成型用纳米碳化硅模具
Jihyum Shin, S. Tanaka, M. Esashi
This paper reports the first result of press molding of Pyrex glass using a silicon carbide (SiC) mold with nanopatterns. First, the nanopatterns were formed on a silicon substrate by electron beam lithography and fast atom beam (FAB) etching. To transfer these patterns to SiC, SiC was deposited on the patterned silicon substrate, and the SiC surface was polished to mirror finish. Subsequently, a SiC ceramic plate was bonded to the polished SiC surface using sputter deposited nickel as an interlayer. Finally, the silicon substrate was etched to release the SiC mold. Using the fabricated SiC molds without an anti-sticking layer, we succeeded in press-molding Pyrex glass (Corning 7740) at 800 degC. In this process, we found surface roughening problem, which occurs in SiC atmospheric vapor deposition on FAB-etched areas. This is due to damage in silicon by FAB, and enhanced under the existence of surface natural oxide.
本文报道了用纳米图案碳化硅(SiC)模具压制成型耐热玻璃的第一个结果。首先,通过电子束光刻和快速原子束(FAB)蚀刻在硅衬底上形成纳米图案。为了将这些图案转移到SiC上,将SiC沉积在图案化的硅衬底上,并将SiC表面抛光至镜面光洁度。随后,用溅射沉积的镍作为中间层将SiC陶瓷板粘结在抛光后的SiC表面上。最后,蚀刻硅衬底以释放SiC模具。使用没有防粘层的SiC模具,我们成功地在800℃下压制成型Pyrex玻璃(康宁7740)。在此过程中,我们发现了在fab蚀刻区域的SiC大气气相沉积中出现的表面粗糙问题。这是由于在硅中被FAB破坏,并且在表面天然氧化物的存在下增强。
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引用次数: 8
Workshop Speech: Commercialization of MEMS/NEMS in Tohoku University Open Collaboration 研讨会演讲:东北大学开放合作中MEMS/NEMS的商业化
M. Esashi
MEMS (Micro Electro Mechanical Systems) have been fabricated using advanced micromachining based on an extended semiconductor microfabrication. Sophisticated MEMS device used as a high performance rotating gyroscope for navigation control systems was developed. A 1.5 mm diameter silicon ring rotor is electrostatically levitated and rotated at 75,000rpm using high speed digital signal control. Two-axes rotation and three-axes acceleration are detected simultaneously with high precision. Small size packaged MEMS devices such as integrated capacitive pressure sensor, diaphragm vacuum sensor and MEMS relay for LSI tester have been fabricated using a wafer level packaging using a glass with electrical feedthroughs. The MEMS relay performs high frequency response up to 20 GHz and high reliability owing to the hermetic sealing. Active catheters, fine blood pressure sensors used in a blood vessel and endoscope with laser therapy function have been developed for minimal invasive medicine using MEMS based assembly. As NEMS (Nano Electro Mechanical Systems) which include nano structure, arrayed systems as multiprobe data storage and massively parallel electron beam lithography system have been developed using a glass with high density electrical feedthroughs. Monolithic XYZ-stage has been also developed for the arrayed systems. Highly sensitive cantilever resonator and micro probes have been also developed as the NEMS.
MEMS(微电子机械系统)是基于半导体微加工技术的先进微加工技术。研制了一种用于导航控制系统的高性能旋转陀螺仪的精密MEMS器件。一个1.5毫米直径的硅环转子是静电悬浮和旋转75000 rpm使用高速数字信号控制。两轴旋转和三轴加速度同时检测,精度高。小型封装MEMS器件,如集成电容压力传感器、膜片真空传感器和用于LSI测试仪的MEMS继电器,已经使用带电馈线的玻璃晶圆级封装制造。MEMS继电器具有高达20 GHz的高频响应和高可靠性,因为它是密封的。主动导管、用于血管的精细血压传感器和具有激光治疗功能的内窥镜已被开发用于基于MEMS的微创医学。随着纳米机电系统(NEMS)的发展,包括纳米结构,阵列系统作为多探头数据存储和大规模并行电子束光刻系统已被开发利用高密度电馈线的玻璃。单片xyz级也为阵列系统开发。高灵敏度的悬臂谐振器和微探针也被发展为NEMS。
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引用次数: 0
A wearable humidity sensor with hydrophilic membrane by Soft-MEMS techniques 基于软mems技术的可穿戴式亲水膜湿度传感器
Y. Miyoshi, T. Tkeuchi, T. Saito, H. Saito, H. Kudo, K. Otsuka, K. Mitsubayashi
An electric conductimetric sensor (thickness: 80 mum) constructed in a sandwich configuration with a hydrophilic poly-tetrafluoroethylene membrane placed between two gold deposited layers was evaluated for use as a moisture sensor. The humidity level was measured by electrical conductivity of the device using the multifrequency LCR-meter at frequencies ranging from 100 Hz to 100 k Hz, the device was calibrated at 100 Hz against the moisture air over the range of 30 - 85 % RH, which includes normal humidity level in the atmosphere and physiologic air such as breath and sweating. The response sensitivity of the conductimetric device was extremely high (i.e. less than 1 sec. for conductivity shift between humid air of 80 % RH and dried air of -60 degC dew point) even for recovery to dried air. The sensor performance was reproducible over multiple measurements, showing the highly reproducibility with a coefficient of variation of 1.77 % (n = 5).
在两个金沉积层之间放置亲水聚四氟乙烯膜的夹层结构中构建了一种导电传感器(厚度:80微米),评估了其作为湿度传感器的用途。湿度水平使用多频LCR-meter在100 Hz至100 k Hz的频率范围内通过设备的电导率来测量,该设备在100 Hz下针对30 - 85% RH范围内的潮湿空气进行校准,其中包括大气中的正常湿度水平和生理空气(如呼吸和出汗)。电导装置的响应灵敏度非常高(即,在80% RH的潮湿空气和-60℃露点的干燥空气之间的电导率变化小于1秒),即使恢复到干燥空气。该传感器的性能可重复多次测量,重复性高,变异系数为1.77% (n = 5)。
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引用次数: 3
A Molecular Dynamics on the Thermally Developing Flow of Alanine in Nano-Channel 纳米通道中丙氨酸热发展流动的分子动力学研究
D.T.W. Lin
The flow of the body fluid in the bio-chip and local metabolism require general solutions for the thermally developing flow model in bio-tissue. An algorithm based on the molecular dynamics (MD) and the GROMACS protein data bank is developed to solve the thermally developing bio-flow problem. The flow of the Alanine in the nano-channel driven by a constant external force and applied the thermal boundary are studied. Both global effect (effective channel width) and local effect (thermal boundary) are examined to demonstrate the features of the distributions of velocity in the system. This algorithm can be applied in the design of bio-chip's channel and the building of fundamental phenomena of the burn or frostbite.
生物芯片中体液的流动和局部代谢需要生物组织中热发展流动模型的通用解决方案。提出了一种基于分子动力学(MD)和GROMACS蛋白质数据库的算法来解决热发展的生物流动问题。研究了恒定外力驱动下丙氨酸在纳米通道内的流动。考察了整体效应(有效通道宽度)和局部效应(热边界),以说明系统中速度分布的特征。该算法可用于生物芯片通道的设计和烧伤、冻伤基本现象的构建。
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引用次数: 1
Characteristics of the PPy Material as pH Sensitive Membrane PPy材料作为pH敏感膜的特性研究
Zumin Wang, Z. Ren, Jinghong Han, C. Bian, S. Xia
A monolithic pH sensor system has been studied and developed, based on standard CMOS technology. The micro system includes an on-chip integration of differential ISFET/REFET sensing devices, metal constructed pseudo reference electrode (PRE) and their relative signal processing circuits. We mainly present the development of PPy(polypyrrole) membrane by the way of electrochemical polymerization, which was grown on the gate of ISFET, as pH sensitive material. With a series of experiments, a high sensitivity of 56mV/pH was achieved within the pH range from 1 to 12. In the end, we discussed the influence of reagents and polymerization parameters on the pH sensor system.
研究开发了一种基于标准CMOS技术的单片pH传感器系统。该微系统包括片上集成的差分ISFET/REFET传感器件、金属构造的伪参比电极(PRE)及其相关的信号处理电路。本文主要介绍了电化学聚合法制备聚吡咯(PPy)膜,并将其作为pH敏感材料生长在ISFET栅极上。通过一系列实验,在1 ~ 12的pH范围内获得了56mV/pH的高灵敏度。最后讨论了试剂和聚合参数对pH传感器系统的影响。
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引用次数: 4
Prediction of secondary and tertiary structures of hemoglobin Constant Spring 血红蛋白二级和三级结构的预测
V. Wiwanitkit
Hemoglobin (Hb) constant spring (CS) disorder is an important hemoglobinopathy with the highest endemicity in Southeast Asia. The role of Hb CS instability in altered red cell morphology relative to the thalassemia-like deficit of alpha globin mRNA has not been entirely resolved and needs additional structural study for clarification. Here, amino acid sequence of human alpha globin was extracted using ExPASY and used for further mutated to Hb CS disorder. The derived sequences, alpha globin chains in both normal and Hb CS disorder, were used for further investigation for secondary structures. Modeling of these proteins for secondary structure was done using the NNPREDICT server. Of interest, the secondary structure of human alpha globin chains of normal and Hb CS disorder are calculated and presented. Based on this information, the main difference between the globin chains of normal and Hb CS disorder is the elongation in the structure. Alpha globin chain of hemoglobin disorder contains more helical residues in elongated part than normal. In addition, the tertiary structure of Hb CS was also modeled using Pepstr server.
血红蛋白(Hb)恒春症(CS)是东南亚地区最常见的一种重要的血红蛋白病。血红蛋白CS不稳定性在与地中海贫血样α -珠蛋白mRNA缺陷相关的红细胞形态改变中的作用尚未完全解决,需要进一步的结构研究来澄清。使用ExPASY提取人α -珠蛋白的氨基酸序列,用于进一步突变为Hb CS疾病。衍生的序列,正常和Hb CS疾病的α珠蛋白链,被用于进一步研究二级结构。利用NNPREDICT服务器对这些蛋白质的二级结构进行建模。有趣的是,计算并呈现了正常和Hb CS紊乱的人α -珠蛋白链的二级结构。基于这些信息,正常和Hb CS紊乱的珠蛋白链之间的主要区别是结构的伸长。血红蛋白紊乱的α -球蛋白链在细长部分含有比正常更多的螺旋残基。此外,还利用Pepstr服务器对Hb CS的三级结构进行了建模。
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引用次数: 0
Carbon Nanotube-based Nanoprobe Electrode 碳纳米管基纳米探针电极
Takeshi Kawano, C. Y. Cho, Liwei Lin
This paper reports a 10-nm in diameter nanoprobe electrode made of carbon nanotube (CNT) for possible electrophysiological measurements for biomedical applications. The nanoprobe is based on an individual carbon nanotube fabricated by a controlled local growth process and subsequently encapsulated with an insulating layer of Parylene-C. It is integrated with a silicon microstructure with a total length of 5mum and its tip at the distal end is locally heated to expose about 100nm-long CNT as the sensing port. We believe this nano scale CNT probe, with its high strength and Young's modulus, may act as a low-invasive intracellular electrode for measurements inside cells or neurons.
本文报道了一种直径为10nm的碳纳米管(CNT)纳米探针电极,可用于生物医学领域的电生理测量。该纳米探针基于单个碳纳米管,通过可控的局部生长过程制备,随后包裹有聚苯乙烯- c绝缘层。它集成了一个总长度为5nm的硅微结构,其远端尖端局部加热,暴露出约100nm长的碳纳米管作为传感端口。我们相信,这种具有高强度和杨氏模量的纳米尺度碳纳米管探针可以作为一种低侵入性的细胞内电极,用于细胞或神经元内部的测量。
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引用次数: 9
Elastic Field of a Nano Disk Shape Defect in an fcc Thin Film fcc薄膜中纳米圆盘状缺陷的弹性场
H. Shodja, L. Pahlevani, E. Hamed
In this paper, we develop a theory to study the nano defects of various geometries within thin films. The considered thin films have faced centered cubic (fcc) structure. The eigenstrain method is combined with the long-range Sutton-Chen (SC) inter-atomic potential function which is appropriate for fcc crystals. The disturbance caused by a defect in a thin film is determined from the equilibrium equation using the discrete Fourier transformation. The disturbed field is also determined using three dimensional (3D) molecular dynamics (MD) simulations in which the constant NVT ensemble is applied to the atomic system. For illustration, the problem of nano disk shape defect in thin film is studied by both the proposed theory and MD simulation. To compare the result of the present theory with that of continuum theory of elasticity, the problem of prismatic dislocation loop in an infinite domain is also considered.
在本文中,我们发展了一种理论来研究薄膜中不同几何形状的纳米缺陷。所研究的薄膜具有中心立方(fcc)结构。本征应变法与适用于fcc晶体的长程Sutton-Chen (SC)原子间势函数相结合。利用离散傅里叶变换从平衡方程出发,确定了薄膜中缺陷引起的扰动。扰动场也通过三维(3D)分子动力学(MD)模拟来确定,其中恒定NVT系综应用于原子系统。为说明这一问题,本文采用所提出的理论和MD模拟方法对薄膜中的纳米圆盘状缺陷进行了研究。为了与弹性连续介质理论的结果进行比较,还考虑了无限域中的棱柱位错环问题。
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引用次数: 0
DNA-Directed Self-Assembly of Microscopic 1-D Carbon Nanotube Wire 微观一维碳纳米管线的dna定向自组装
Jin-Woo Kim, N. Kotagiri, R. Deaton, S. Tung
Molecular wire construction using DNA-directed self-assembly of multi-walled carbon nanotubes (MWNTs) has been attempted. MWNTs were selected owing to their exceptional electrical and structural properties. DNA, which possesses specific molecular recognition properties, served as the engine for the assembly. Non-crosshybridizing (NCH) sequences were designed to impart specificity and high throughput reaction. Stepwise manufacturing of the wire was accomplished by first functionalizing the NCH 20 base pair single-stranded sequences to the tips of MWNT using amide linkage. The adducts were then utilized to self-assemble 1D nanotube wire through DNA hybridization reactions between two complementary ssDNAs functionalized to the MWNT tips. TEM, epi-fluorescent microscopy and AFM analyses showed successful assemblies of micrometer-scale 1D MWNT-DNA wires, ranging from 2.7-20 mum. The results demonstrate great potentials of the DNA-guided self-assembly process, which would provide an uncomplicated, versatile and inexpensive way to manufacture micrometer-scale molecular wires.
利用dna定向自组装的多壁碳纳米管(MWNTs)构建分子线已被尝试。MWNTs因其特殊的电学和结构特性而被选中。具有特定分子识别特性的DNA充当了组装的引擎。非交叉杂交(NCH)序列设计具有特异性和高通量反应。通过首先使用酰胺连接将nch20碱基对单链序列功能化到MWNT的尖端,逐步制造金属丝。然后利用加合物通过两个互补的被功能化为MWNT尖端的ssdna之间的DNA杂交反应自组装1D纳米管丝。透射电镜、荧光显微镜和原子力显微镜分析显示,成功组装了微米尺度的1D MWNT-DNA线,长度从2.7-20 μ m不等。结果表明,dna引导的自组装工艺具有巨大的潜力,它将为制造微米级分子线提供一种简单、通用和廉价的方法。
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引用次数: 0
Electrohydrodynamic (EHD) Micro-Boat 电流体动力(EHD)微型船
Jiun-Min Wang, Tzu-Yuan Lin, Lung-Jieh Yang
This paper describes about the fabrication and testing of a novel electrohydrodynamic (EHD) micro-boat using parylene MEMS technology. The driven force of micro-boat utilizes the reaction force of the EHD, with planar electrodes, to pump nonpolar liquid. As a result, by applying a DC voltage of 30-40 V the instantaneous moving velocity of the EHD micro-boat is about 6.5 mm/min.
本文介绍了利用聚对二甲苯微机电系统技术制造一种新型电流体动力(EHD)微船并进行了测试。微船的驱动力利用EHD的反作用力,采用平面电极泵送非极性液体。因此,通过施加30-40 V的直流电压,EHD微型船的瞬时移动速度约为6.5 mm/min。
{"title":"Electrohydrodynamic (EHD) Micro-Boat","authors":"Jiun-Min Wang, Tzu-Yuan Lin, Lung-Jieh Yang","doi":"10.1109/NEMS.2007.352087","DOIUrl":"https://doi.org/10.1109/NEMS.2007.352087","url":null,"abstract":"This paper describes about the fabrication and testing of a novel electrohydrodynamic (EHD) micro-boat using parylene MEMS technology. The driven force of micro-boat utilizes the reaction force of the EHD, with planar electrodes, to pump nonpolar liquid. As a result, by applying a DC voltage of 30-40 V the instantaneous moving velocity of the EHD micro-boat is about 6.5 mm/min.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"688 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116169179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
期刊
2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems
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