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Materialy VIII Vserossijskoj konferencii s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka»最新文献

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External respiration and gas exchange in conditions of maximum load at different levels of the body's aerobic capacity 体外呼吸和气体交换在最大负荷条件下不同水平的身体有氧能力
S. Vinogradov
The study of the characteristics of the reactions of the links of external respiration and gas exchange at various stages of performing a step-increasing load and at maximum load with various aerobic capabilities of the body was carried out. The data obtained indicate that the level of aerobic capabilities of the body determines the characteristics of the reactions of the links of external respiration and gas exchange at various stages of performing a step-increasing load and at maximum load. Key words: functional reserves of organism, gas transportation system, maximum oxygen consumption, aerobic capacity of organism, gas exchange.
研究了体外呼吸和气体交换环节在执行增步负荷的不同阶段和在最大负荷下与身体各种有氧能力的反应特征。所获得的数据表明,身体的有氧能力水平决定了在执行增步负荷和最大负荷的各个阶段外呼吸和气体交换环节的反应特征。关键词:机体功能储备,气体输送系统,最大耗氧量,机体有氧能力,气体交换。
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引用次数: 0
Synthesis of chelated compounds of amino acids with metals 氨基酸与金属螯合化合物的合成
A. A. Yamskikh, L. A. Ivanova
The article describes the reactions of glycine synthesis with alkaline, alkaline-earth and divalent 3-d metals, which were carried out during the experiment. Hydroxides or sulfates of lithium, magnesium, calcium, manganese, iron, copper, zinc, cobalt and sodium were used as reagents for the synthesis. The physicochemical properties of the obtained compounds were studied. Keywords: chelates, glycinates of alkaline and alkaline earth metals, glycinates of divalent 3-d metals.
本文介绍了实验中甘氨酸与碱性、碱土和二价三维金属的合成反应。锂、镁、钙、锰、铁、铜、锌、钴和钠的氢氧化物或硫酸盐被用作合成试剂。对所得化合物的理化性质进行了研究。关键词:螯合物,碱土金属甘氨酸盐,二价三维金属甘氨酸盐。
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引用次数: 0
The research of neuroplasticity by the Visual Continuous Performance Tasks in teaching by the method of complex music and vocal education 视觉连续表演任务在复杂音乐声乐教学中的神经可塑性研究
D.M. Ogorodnov, S. A. Evdokimov, Y. Kropotov
The Methodology of Comprehensive Music and Vocal Education (CMVE) is a powerful pedagogical instrument which helps a person's to improve its voice and musicality. Because several zones, such is auditory, somatosensory, motor (mainly due to the inclusion of hands and speech motor apparatus) and visual are actively involved, which is active contributes to a change in the picture of the dominant centers of the cortex, stimulates and develops such cognitive functions as attention, speech, memory, praxis. Neuroplasticity is closely related to music education, as indicated, for example, by such work as G. Schlaug, which explains some of the sensorimotor and cognitive improvements associated with music education. This allows us to assume and test the effects of neuroplasticity when working according to the CMVE method, which also uses different modalities. To investigate event-related potentials, the authors use a two-stimulus selective attention test (VCPT Go / NoGo test). Key words: EEG, ERP, VCPT-task, musical-vocal education by D.E. Ogorodnov.
综合音乐声乐教育方法是一种有效的教学手段,它可以帮助人们提高声音和音乐性。由于听觉、体感、运动(主要包括手和语言运动器官)和视觉等几个区域都积极参与,这种活跃有助于改变大脑皮层主要中心的图像,刺激和发展诸如注意力、语言、记忆、实践等认知功能。神经可塑性与音乐教育密切相关,例如,G. Schlaug的研究解释了一些与音乐教育相关的感觉运动和认知改善。这使我们能够假设并测试根据CMVE方法工作时神经可塑性的影响,CMVE方法也使用不同的模式。为了研究事件相关电位,作者使用了双刺激选择性注意测试(VCPT Go / NoGo测试)。关键词:脑电图,ERP, vcpt任务,奥格罗诺夫的声乐教育
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引用次数: 0
The role of disorders in the functional activity of platelets in the pathogenesis of microcirculatory disorders in patients with catarrhal gingivitis 血小板功能活动紊乱在卡他性牙龈炎患者微循环紊乱发病机制中的作用
V. Kitaeva, A. Smolkina
A comprehensive examination of patients with chronic catarrhal gingivitis and with exacerbation of chronic catarrhal gingivitis with the inclusion of indicators of the microcirculatory link of the hemostasis system was carried out. In patients with exacerbation of chronic catarrhal gingivitis, platelet aggregation activity is increased compared to that in healthy individuals. This is accompanied by a statistically significant increase in the maximum degree of aggregation, a change in the time to reach the maximum degree of platelet aggregation Key words: platelet aggregation, catarrhal gingivitis, exacerbation of chronic catarrhal gingivitis.
对慢性卡他性牙龈炎及慢性卡他性牙龈炎加重患者进行综合检查,包括止血系统微循环环节指标。慢性卡他性牙龈炎加重患者的血小板聚集活性比健康人增加。同时伴有最大聚集度增高,血小板达到最大聚集度的时间发生变化。关键词:血小板聚集,卡他性牙龈炎,慢性卡他性牙龈炎加重。
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引用次数: 0
Adaptive chemoreceptor plasticity and reactivity of the cardio-respiratory system in athletes under hypoxic loads 低氧负荷下运动员心肺系统的适应性化学受体可塑性和反应性
N. Balioz, S.G. Krivoshshekov
An exploration of 110 healthy men (not involved in sports and athletes) with the use of hypoxic loads was carried out. It is established that the specifics of the regulation of gas exchange depend on the nature of training loads (aerobic or mixed), which are manifested in the parameters of chemoreflector reactivity, the pattern of external respiration, gas exchange and activity of the autonomic nervous system under hypoxic load. As sports qualifications grow, the mechanisms of intersystem integration of the functions of the cardio-respiratory system are improved, which is manifested in an increase in cardiorespiratory coherence. Key words: athletes, hypoxia, cardiorespiratory system, gas exchange of the body, chemoreceptor reactivity.
对110名健康男性(不参与体育运动和运动员)进行了低氧负荷的研究。研究表明,气体交换调节的具体方式取决于训练负荷的性质(有氧或混合),表现在低氧负荷下的化学反射反应性、外呼吸模式、气体交换和自主神经系统活性等参数。随着体育素质的提高,心肺系统功能的系统间整合机制得到完善,表现为心肺相干性的增强。关键词:运动员,缺氧,心肺系统,身体气体交换,化学受体反应性。
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引用次数: 0
Morphofunctional features of proliferating cells exposed to PSMA peptide PSMA肽作用下增殖细胞的形态功能特征
N. Mikheeva, E.P. Drozhdina, N. A. Kurnosova
The effect of the synthetic PSMA peptide on dividing cells of laboratory animals was studied. The experiment was carried out on male white laboratory mice of the BALB/c-line. The toxic effect of PSMA peptidi was evaluated at therapeutic (1.4 μg / kg of animal weight or 0.04 μg / animal) and subtoxic (140 μg / kg of animal weight or 4.0 μg / animal) doses. The cytotoxic effect of PSMA peptide on red bone marrow cells and cambial intestinal cells of the of laboratory mice was determined. A decrease in the proliferative activity of the colon crypt cells was revealed upon administration of a subtoxic dose of the PSMA peptide and there were no signs of toxic damage to the red bone marrow cells of animals. Key words: toxicity, proliferation, synthetic peptides, mitotic index, micronucleus test.
研究了合成的PSMA肽对实验动物分裂细胞的影响。实验对象为BALB/c系雄性实验白鼠。在治疗剂量(1.4 μg / kg动物体重或0.04 μg /动物)和亚毒性剂量(140 μg / kg动物体重或4.0 μg /动物)下评估PSMA肽的毒性作用。测定了PSMA肽对实验小鼠红骨髓细胞和形成层肠细胞的细胞毒作用。在给予亚毒性剂量的PSMA肽后,结肠隐窝细胞的增殖活性下降,动物的红骨髓细胞没有毒性损伤的迹象。关键词:毒性,增殖,合成肽,有丝分裂指数,微核试验。
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引用次数: 0
Forecasting the radiation background in the territories of Kazakhstan located near the uranium mining industries 预测哈萨克斯坦铀矿工业附近地区的辐射本底
A. Ismailova, N.A. Nurbaeva
A significant part of the territory of Kazakhstan is characterized by a high natural background radiation of soils and rocks, the spread of natural ground and underground waters with high concentrations of radionuclides in the regions of uranium, thorium and rare metal ore provinces and regions. Therefore, conducting high-quality radio monitoring of the state of the environment using modern information systems will make it possible to predict the background radiation in a timely manner and outline measures to reduce environmental risks to the health of the nation as a whole. Key words: radioecology, monitoring, life safety, radionuclides, national health.
哈萨克斯坦领土的很大一部分地区的特点是土壤和岩石的天然本底辐射高,在铀、钍和稀有金属矿省和地区的天然地表水和地下水的放射性核素浓度很高。因此,利用现代信息系统对环境状况进行高质量的无线电监测,将有可能及时预测本底辐射,并概述减少对整个国家健康的环境风险的措施。关键词:放射生态学监测生命安全放射性核素国民健康
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引用次数: 0
Personalized approach in optimizing the treatment of acute pancreatitis 个性化方法优化急性胰腺炎的治疗
A. P. Vlasov, V. A. Trofimov, S. Al'-Kubaysi, N. Myshkina, T. A. Muratova, L. N. Umnov, M. Khachaturov
In order to determine the effectiveness of the use of remaxol based on a personalized approach in patients with acute pancreatitis, based on the establishment of gene polymorphism of integrin beta-3 (T1565C, ITGB3), integrin alpha-2 (C807T, ITGA2), fibrinogen (G(-455)A, FGB) and plasminogen activator inhibitor (5G(-675)4G, SERPINE1), a study of 84 patients with acute pancreatitis of varying severity was conducted. As a result of the study, it was proved that in order to increase the effectiveness of treatment of patients with severe acute pancreatitis upon admission, in addition to clinical, laboratory and instrumental studies, it is necessary to conduct genetic testing of the genotypes of the polymorphism of the GPIIa gene (T1565C), ITGA2 (C807T), FGB (G(-455)A) and SERPINE1 (5G(-675)4G) to develop a personalized approach in the treatment of this severe category of patients. Key words: acute pancreatitis, genotype, DNA diagnostics, genetic testing of genotypes, personalized medicine.
为了确定基于个体化方法的瑞美索在急性胰腺炎患者中的应用效果,在建立整合素β -3 (T1565C、ITGB3)、整合素α -2 (C807T、ITGA2)、纤维蛋白原(G(-455) a、FGB)和纤溶酶原激活物抑制剂(5G(-675)4G、SERPINE1)基因多态性的基础上,对84例不同严重程度的急性胰腺炎患者进行了研究。本研究结果证明,为了提高重症急性胰腺炎患者入院时的治疗效果,除临床、实验室和仪器研究外,还需要对GPIIa基因(T1565C)、ITGA2 (C807T)、FGB (G(-455) a)和SERPINE1 (5G(-675)4G)的多态性基因型进行基因检测,以制定治疗这类重症患者的个性化方法。关键词:急性胰腺炎,基因型,DNA诊断,基因型基因检测,个体化治疗
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引用次数: 0
Effect of combined action of arsenic and antimony compounds on renal function in the subchronic test 亚慢性试验中砷锑化合物联合作用对肾功能的影响
N. Shestakov, R. Aizman, A. S. Ogudov, N. F. Chuenko
The study was conducted on male Wistar rats. We used 4 mathematically related series of doses prepared by sequential dilution of water from a man-made lake according to the scheme: arsenic: 0.15 - 0.05 - 0.016 - 0.0055, antimony: 0.68 - 0.227 - 0.075 - 0.025 mg/l. The animals were examined before inoculation (background), on days 40 and 90 of the experiment, taking into account the processes of cumulation of chemical elements in the kidneys. New data on the nature of nephrotoxic effects of arsenic and antimony in the long-term combined intake into the body of laboratory animals have been obtained. Key words: water from a man-made lake, arsenic and antimony compounds, Wistar rats, nephrotoxicity.
本研究以雄性Wistar大鼠为实验对象。我们使用了4个数学上相关的系列剂量,这些剂量是由一个人工湖的水按顺序稀释得到的:砷:0.15 - 0.05 - 0.016 - 0.0055,锑:0.68 - 0.227 - 0.075 - 0.025 mg/l。在接种前(背景),在实验的第40天和第90天对动物进行检查,考虑到化学元素在肾脏中的积累过程。获得了实验动物长期联合摄入砷和锑对肾毒性作用性质的新数据。关键词:人工湖水体;砷锑化合物;Wistar大鼠;
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引用次数: 0
Еffects of percutaneous electrical stimulation of the spinal cord in combination with mechanotherapy on changes in systemic and regional hemodynamics Еffects经皮脊髓电刺激联合机械治疗对全身和局部血流动力学的影响
V. Golodnova, S. Ananyev, Y.Y. Bikbaeva, M. Balykin, I. Antipov
Objective: to evaluate changes in systemic and cerebral hemodynamics during percutaneous electrical stimulation of the spinal cord and in combination of electrical stimulation with mechanotherapy. Methodology. The subjects underwent percutaneous electrical stimulation of the spinal cord, the duration of the session was 5 minutes. Mechanotherapy was performed using a treadmill. The subjects performed walking at a power of 25W. for 5 minutes. Hemodynamics was evaluated before and after the electrical stimulation session, as well as before and after the mechanical therapy session on the track in combination with percutaneous electrical stimulation of the spinal cord. To study systemic and regional hemodynamics, a rheograph-polyanalyzer "REAN-POLY" was used. Results. Electrical stimulation of the spinal cord does not lead to significant changes in systemic and cerebral hemodynamics. Percutaneous electrical stimulation of the spinal cord in combination with physical exertion leads to reactive changes in systemic hemodynamics, increased blood filling and venous outflow, against the background of a decrease in peripheral resistance of cerebral vessels. Key words: electrostimulation, percutaneous electrostimulation, mechanotherapy, systemic hemodynamics, regional hemodynamics.
目的:探讨经皮脊髓电刺激及电刺激联合机械治疗对全身及脑血流动力学的影响。方法。受试者接受经皮脊髓电刺激,持续时间5分钟。机械治疗采用跑步机进行。受试者在25瓦的功率下行走。5分钟。在电刺激前后,以及机械治疗联合经皮脊髓电刺激前后,评估血流动力学。为了研究全身和局部血流动力学,使用了流变分析仪“REAN-POLY”。结果。脊髓电刺激不会导致全身和脑血流动力学的显著变化。经皮脊髓电刺激与体力消耗相结合可导致全身血流动力学的反应性改变,血液充血和静脉流出增加,背景是脑血管外周阻力降低。关键词:电刺激,经皮电刺激,机械治疗,全身血流动力学,局部血流动力学。
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引用次数: 0
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Materialy VIII Vserossijskoj konferencii s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka»
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