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Japanese Journal of Head and Neck Cancer最新文献

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A case of severe delayed hemorrhage after salvage transoral surgery for recurrent oropharyngeal cancer 复发口咽癌抢救经口手术后严重迟发性出血1例
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.5981/jjhnc.46.401
Y. Harada, S. Miyamoto, Y. Seino, T. Matsuki, K. Kano, Shohei Tsutsumi, Ayako Furuki, Kaho Momiyama, T. Yamashita
Transoral videolaryngoscopic surgery (TOVS) for pharyngeal and laryngeal cancer is a function-preserving surgery with low invasion and risk. However, it remains unclear whether TOVS is suitable as salvage surgery. We report a case that suffered severe postoperative hemorrhage after TOVS for recurrent tumor after chemo-radiotherapy despite the intention of minimally invasive salvage surgery. A 68-year-old man underwent TOVS due to T1 recurrent oropharyngeal cancer of the anterior wall after 8 years of initial treatment by chemoradiotherapy. However, the patient suffocated from severe hemorrhage on the 16th postoperative day, requiring emergency tracheotomy in a hospital ward and hemostasis in an operat-ing room. He has been followed for 18 months after surgery with functional preservation and no disease. TOVS might be applicable for salvage treatment as well as initial treatment as a function-preserving surgery. However, because it can lead to life-threatening postoperative bleeding especially in cases after radiotherapy, careful case selection and surgical planning are necessary.
经口视频喉镜手术治疗咽喉癌是一种低侵袭、低风险的功能保留手术。然而,TOVS是否适合作为挽救性手术仍不清楚。我们报告一个病例,在化疗后复发肿瘤进行TOVS后,尽管打算进行微创抢救手术,但仍发生严重的术后出血。一名68岁男性患者在接受放化疗8年后,因T1复发口咽癌前壁而行TOVS。然而,患者术后第16天因严重出血而窒息,需要在医院病房紧急切开气管并在手术室止血。术后随访18个月,功能完好,无疾病。TOVS既可用于保留功能的手术,也可用于挽救性治疗。然而,由于它可能导致危及生命的术后出血,特别是在放疗后的病例中,仔细的病例选择和手术计划是必要的。
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引用次数: 0
Lateral retropharyngeal lymph node metastasis in oral squamous cell carcinomas: a review of the Japanese literature 口腔鳞状细胞癌的侧咽后淋巴结转移:日本文献综述
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.5981/jjhnc.46.31
Y. Kimura, K. Araki
Metastasis of the lateral retropharyngeal lymph nodes (LRPNs) from oral squamous cell carcinoma is very rare, and there are few case reports in the literature. In this study, we researched reported cases in the Japanese literature, including our own cases, to confirm the clinical characteristics of oral cancer patients with LRPN metastases. We analyzed: age and gender of the patients, primary tumor locations, T-stage, histological differentiation, N-stage, number and size of LRPN metastases, LRPN metastasis side (ipsilateral or contralateral to the primary site, neck metastasis), duration from treatment of the primary site and neck or neck metastasis to LRPN metastasis, relationship between late LRPN metastasis and treatment methods of the primary site and / or neck, treatment methods of LRPN metastases, treatment results, survival time from detecting LRPN, and prognosis. As a result, only 22 cases could be analyzed. LRPN metastasis develops less frequently in oral squamous cell carcinoma, may develop contralaterally (23%), and is correlated with low survival rate (18%). Surgical treatment is suggested as a better method because of its high control rate of LRPN metastasis (80%). However, in order to improve prognosis, earlier detection by imaging diagnosis should be performed.
口腔鳞状细胞癌发生咽后外侧淋巴结转移是非常罕见的,文献中很少有病例报道。在本研究中,我们研究了日本文献中报道的病例,包括我们自己的病例,以确认口腔癌患者LRPN转移的临床特征。我们进行了分析:患者的年龄、性别、原发部位、t分期、组织学分化、n分期、LRPN转移的数量和大小、LRPN转移侧(原发部位同侧或对侧、颈部转移)、从原发部位和颈部转移到LRPN转移的持续时间、LRPN晚期转移与原发部位和/或颈部治疗方法的关系、LRPN转移的治疗方法、治疗结果、检测到LRPN后的生存时间及预后。因此,只能分析22例。LRPN转移在口腔鳞状细胞癌中较少发生,可能发生对侧(23%),并且与低生存率(18%)相关。由于LRPN转移控制率高(80%),建议手术治疗是较好的方法。然而,为了改善预后,应及早通过影像学诊断发现。
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引用次数: 0
Mediastinal tracheostomy 纵隔气管造口术
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.5981/jjhnc.46.371
K. Kuba, Yuichiro Enoki, H. Inoue, Takahiro Hayashi, Satoko Matsumura, Yasunao Kogashiwa, Yasuhiro Ebihara, M. Nakahira, M. Sugasawa, Hideki Yokogawa, S. Sarukawa
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引用次数: 0
Head and Neck Cancer: Psychological and Psychosocial Effects 头颈癌:心理和社会心理影响
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.1007/978-3-030-27881-6
C. Fundakowski
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引用次数: 0
Mucosal malignant melanoma of the head and neck: Clinical analysis of 12 cases 头颈部黏膜恶性黑色素瘤12例临床分析
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.5981/jjhnc.46.365
Kazuhiro Mitsumura, M. Ōsaki, M. Hara, S. Kinoshita, Keitaro Nagano, Akio Hatanaka, M. Shimoda, T. Hashimoto, Yusuke Yamamoto, Hideki Fujihara, W. Nishijima, Eikichi Tokunaga
The present report describes the treatment of 12 patients with primary mucosal malignant melanoma of the head and neck who visited our department between 2011 and 2017. There were 6 men and 6 women, aged 61-90 years (median, 76.5 years), and the observation period was 7-165 months (median, 37 months). Further, 11 patients (92%) presented with primary lesions located in the nasal/paranasal cavities and 1 patient (8%) with the primary lesion located in the oral cavity. The 3-year overall survival rate, as assessed using the Kaplan-Mei-er method, was 56%. Among 8 patients with primary malignant melanoma of the nasal/paranasal cavities who underwent carbon-ion radiotherapy or surgery as a radical treatment, the 3-year local control and 3-year recur-rence-free survival rates were 56% and 38%, respectively. The local control rate was higher in the carbon-ion radiotherapy group. In 12 patients, the 5-year incidence of distant metastasis was as high as 75, and
本报告描述了2011年至2017年12例头颈部原发性黏膜恶性黑色素瘤患者的治疗情况。男6例,女6例,年龄61 ~ 90岁(中位76.5岁),观察期7 ~ 165个月(中位37个月)。此外,11名患者(92%)的原发病变位于鼻腔/副鼻腔,1名患者(8%)的原发病变位于口腔。使用Kaplan-Mei-er法评估的3年总生存率为56%。8例原发性鼻/鼻副腔恶性黑色素瘤患者行碳离子放疗或手术根治,3年局部控制生存率为56%,3年无复发生存率为38%。碳离子放疗组局部控制率较高。12例患者5年远端转移发生率高达75%
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引用次数: 0
Pre/Post-operative instruction for patients using ProvoxⓇ voice prosthesis 使用ProvoxⓇ语音假体患者的术前/术后指导
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.5981/jjhnc.46.322
Kiyofumi Sano, H. Fukushima, R. Kamiyama, H. Mitani
cancer, and conducted pre / post-operative instructions for those patients. During the pre-operative period, we observe and assess the patientʼs adherence to our instructions as well as their self-manage-ment capability for daily maintenance after TEP. During the post-operative instruction, it is important to teach the patient how to use a voice prosthesis cleaning brush to make sure they do not break the one-way valve of the Provox, which can easily happen. A clear and thorough explanation is also considered very important.
癌症,并为这些患者进行术前/术后指导。在术前,我们观察和评估患者对我们的指导的依从性以及TEP后日常维护的自我管理能力。在术后指导中,重要的是教患者如何使用假声清洁刷,以确保他们不会破坏声带的单向阀,这很容易发生。一个清晰彻底的解释也被认为是非常重要的。
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引用次数: 1
Clinical analysis of locally advanced squamous cell carcinoma of the tongue along with the transition of neoadjuvant therapy 舌局部晚期鳞状细胞癌伴新辅助治疗过渡的临床分析
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.5981/jjhnc.46.340
Kiminobu Sato, T. Ono, Buichiro Shin, S. Chitose, H. Umeno
We reviewed patients with locally advanced squamous cell carcinoma of the tongue (LASCCT) treated by standard treatment modalities including irradiation followed by surgery (① RT + surgery group), surgery with-out neoadjuvant therapy (② surgery group), and neoadjuvant chemotherapy followed by surgery (③ NAC + surgery group). No significant differences in 5-year locoregional control (LRC), disease-free survival (DFS), or overall survival (OS) rates were shown among the three groups. Furthermore, subgroup analysis by T, N, and clinical stage showed no significant differences of LRC, DFS, or OS among the three groups. The NAC + surgery group tended to have much locoregional recurrence compared to the other groups, although no significant difference of rates of locoregional or distant recurrence was shown among the three groups. Furthermore, the NAC + surgery group, including a higher proportion of advanced T or N stage, tended to have a lower proportion of distant recurrence and a favorable OS compared to the other groups. However, overall survival of the NAC + surgery group was better even though the group included advanced T and N cases. There were some limita-tions of this study; further analysis is required for neoadjuvant therapy.
我们回顾了局部晚期舌鳞状细胞癌(LASCCT)的标准治疗方式,包括放疗后手术(①RT +手术组)、手术不加新辅助治疗(②手术组)和新辅助化疗后手术(③NAC +手术组)。在5年局部区域控制率(LRC)、无病生存率(DFS)或总生存率(OS)方面,三组间无显著差异。此外,根据T、N和临床分期进行亚组分析,三组间LRC、DFS和OS无显著差异。与其他组相比,NAC +手术组的局部复发率更高,但三组之间的局部复发率和远处复发率无显著差异。此外,NAC +手术组,包括更高比例的晚期T期或N期,与其他组相比,往往具有较低的远处复发比例和良好的OS。然而,即使NAC +手术组包括晚期T和N病例,NAC +手术组的总生存率也更好。本研究存在一些局限性;新辅助治疗需要进一步分析。
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引用次数: 0
Proposal for classification of surgery of parotid cancer 腮腺癌手术分类的建议
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.5981/jjhnc.46.270
R. Kawata, M. Higashino, S. Nishikawa, T. Terada
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引用次数: 0
Treatment outcome of hypopharyngeal cancer: A single institutional experience 下咽癌的治疗结果:单一机构经验
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.5981/jjhnc.46.328
Masanobu Mizuta, K. Iwanaga, A. Yoshizawa, Shinichi Sato, H. Tamaki
This retrospective study investigated the treatment outcomes of patients with hypopharyngeal cancer. The study included 100 patients who were treated at our institution from August 2008 to July 2015. The three-year overall survival (OS) rates for Stage 0, Ⅰ, Ⅱ, Ⅲ, and Ⅳ were 100%, 68.6%, 100%, 56.3%, and 42.3%, respectively. An analysis of 82 patients who were treated curatively (median follow-up period: 37 months) revealed that T status was a significant factor for OS and disease-specific survival (DSS); and N status was significant for DSS and distant metastasis-free survival. The sub-group analysis of the patients with Stage Ⅲ and Ⅳ disease showed that surgery and radiotherapy had comparable oncologic outcomes for T1 and T2 disease, whereas, for T3 and T4 disease, surgery had significantly improved outcome in OS and local control as compared to radiotherapy. Although some previous studies have reported that radiotherapy with concurrent chemotherapy had a comparable outcome to surgery even for advanced hypopharyngeal cancer, especially for T3 disease, the current results were inconsistent with those reports. The discrepancy might be caused by differences in the selection of patients for radiotherapy and in the amount of cumulative cisplatin dose in concurrent chemoradiotherapy.
本回顾性研究探讨下咽癌患者的治疗结果。本研究纳入了2008年8月至2015年7月在我院治疗的100例患者。0期、Ⅰ、Ⅱ、Ⅲ和Ⅳ的3年总生存率分别为100%、68.6%、100%、56.3%和42.3%。一项对82例接受治愈治疗的患者(中位随访期:37个月)的分析显示,T状态是OS和疾病特异性生存(DSS)的重要因素;N状态对DSS和无远处转移生存具有重要意义。对Ⅲ和Ⅳ期疾病患者的亚组分析显示,手术和放疗对T1和T2期疾病的肿瘤预后相当,而对T3和T4期疾病,手术与放疗相比,在OS和局部控制方面的预后显著改善。虽然先前的一些研究报道,即使对于晚期下咽癌,特别是对于T3疾病,放疗合并化疗的结果也与手术相当,但目前的结果与这些报道不一致。这种差异可能是由于放疗患者的选择和同步放化疗中顺铂累积剂量的差异造成的。
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引用次数: 0
Investigation of 71 cases of laryngeal preservation surgery of hypopharyngeal cancer 下咽癌保喉手术71例分析
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.5981/jjhnc.46.354
Katsuji Asano, Yousuke Nagai, Y. Somekawa, M. Myoujin, Hikaru Ikeda, Masamichi Nisio, K. Takano
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引用次数: 0
期刊
Japanese Journal of Head and Neck Cancer
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