Y. Harada, S. Miyamoto, Y. Seino, T. Matsuki, K. Kano, Shohei Tsutsumi, Ayako Furuki, Kaho Momiyama, T. Yamashita
Transoral videolaryngoscopic surgery （TOVS） for pharyngeal and laryngeal cancer is a function-preserving surgery with low invasion and risk. However, it remains unclear whether TOVS is suitable as salvage surgery. We report a case that suffered severe postoperative hemorrhage after TOVS for recurrent tumor after chemo-radiotherapy despite the intention of minimally invasive salvage surgery. A 68-year-old man underwent TOVS due to T1 recurrent oropharyngeal cancer of the anterior wall after 8 years of initial treatment by chemoradiotherapy. However, the patient suffocated from severe hemorrhage on the 16th postoperative day, requiring emergency tracheotomy in a hospital ward and hemostasis in an operat-ing room. He has been followed for 18 months after surgery with functional preservation and no disease. TOVS might be applicable for salvage treatment as well as initial treatment as a function-preserving surgery. However, because it can lead to life-threatening postoperative bleeding especially in cases after radiotherapy, careful case selection and surgical planning are necessary.
{"title":"A case of severe delayed hemorrhage after salvage transoral surgery for recurrent oropharyngeal cancer","authors":"Y. Harada, S. Miyamoto, Y. Seino, T. Matsuki, K. Kano, Shohei Tsutsumi, Ayako Furuki, Kaho Momiyama, T. Yamashita","doi":"10.5981/jjhnc.46.401","DOIUrl":"https://doi.org/10.5981/jjhnc.46.401","url":null,"abstract":"Transoral videolaryngoscopic surgery （TOVS） for pharyngeal and laryngeal cancer is a function-preserving surgery with low invasion and risk. However, it remains unclear whether TOVS is suitable as salvage surgery. We report a case that suffered severe postoperative hemorrhage after TOVS for recurrent tumor after chemo-radiotherapy despite the intention of minimally invasive salvage surgery. A 68-year-old man underwent TOVS due to T1 recurrent oropharyngeal cancer of the anterior wall after 8 years of initial treatment by chemoradiotherapy. However, the patient suffocated from severe hemorrhage on the 16th postoperative day, requiring emergency tracheotomy in a hospital ward and hemostasis in an operat-ing room. He has been followed for 18 months after surgery with functional preservation and no disease. TOVS might be applicable for salvage treatment as well as initial treatment as a function-preserving surgery. However, because it can lead to life-threatening postoperative bleeding especially in cases after radiotherapy, careful case selection and surgical planning are necessary.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71242842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Metastasis of the lateral retropharyngeal lymph nodes （LRPNs） from oral squamous cell carcinoma is very rare, and there are few case reports in the literature. In this study, we researched reported cases in the Japanese literature, including our own cases, to confirm the clinical characteristics of oral cancer patients with LRPN metastases. We analyzed: age and gender of the patients, primary tumor locations, T-stage, histological differentiation, N-stage, number and size of LRPN metastases, LRPN metastasis side （ipsilateral or contralateral to the primary site, neck metastasis）, duration from treatment of the primary site and neck or neck metastasis to LRPN metastasis, relationship between late LRPN metastasis and treatment methods of the primary site and / or neck, treatment methods of LRPN metastases, treatment results, survival time from detecting LRPN, and prognosis. As a result, only 22 cases could be analyzed. LRPN metastasis develops less frequently in oral squamous cell carcinoma, may develop contralaterally （23％）, and is correlated with low survival rate （18％）. Surgical treatment is suggested as a better method because of its high control rate of LRPN metastasis （80％）. However, in order to improve prognosis, earlier detection by imaging diagnosis should be performed.
{"title":"Lateral retropharyngeal lymph node metastasis in oral squamous cell carcinomas: a review of the Japanese literature","authors":"Y. Kimura, K. Araki","doi":"10.5981/jjhnc.46.31","DOIUrl":"https://doi.org/10.5981/jjhnc.46.31","url":null,"abstract":"Metastasis of the lateral retropharyngeal lymph nodes （LRPNs） from oral squamous cell carcinoma is very rare, and there are few case reports in the literature. In this study, we researched reported cases in the Japanese literature, including our own cases, to confirm the clinical characteristics of oral cancer patients with LRPN metastases. We analyzed: age and gender of the patients, primary tumor locations, T-stage, histological differentiation, N-stage, number and size of LRPN metastases, LRPN metastasis side （ipsilateral or contralateral to the primary site, neck metastasis）, duration from treatment of the primary site and neck or neck metastasis to LRPN metastasis, relationship between late LRPN metastasis and treatment methods of the primary site and / or neck, treatment methods of LRPN metastases, treatment results, survival time from detecting LRPN, and prognosis. As a result, only 22 cases could be analyzed. LRPN metastasis develops less frequently in oral squamous cell carcinoma, may develop contralaterally （23％）, and is correlated with low survival rate （18％）. Surgical treatment is suggested as a better method because of its high control rate of LRPN metastasis （80％）. However, in order to improve prognosis, earlier detection by imaging diagnosis should be performed.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Kuba, Yuichiro Enoki, H. Inoue, Takahiro Hayashi, Satoko Matsumura, Yasunao Kogashiwa, Yasuhiro Ebihara, M. Nakahira, M. Sugasawa, Hideki Yokogawa, S. Sarukawa
{"title":"Mediastinal tracheostomy","authors":"K. Kuba, Yuichiro Enoki, H. Inoue, Takahiro Hayashi, Satoko Matsumura, Yasunao Kogashiwa, Yasuhiro Ebihara, M. Nakahira, M. Sugasawa, Hideki Yokogawa, S. Sarukawa","doi":"10.5981/jjhnc.46.371","DOIUrl":"https://doi.org/10.5981/jjhnc.46.371","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71242774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.1007/978-3-030-27881-6
C. Fundakowski
{"title":"Head and Neck Cancer: Psychological and Psychosocial Effects","authors":"C. Fundakowski","doi":"10.1007/978-3-030-27881-6","DOIUrl":"https://doi.org/10.1007/978-3-030-27881-6","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90989818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kazuhiro Mitsumura, M. Ōsaki, M. Hara, S. Kinoshita, Keitaro Nagano, Akio Hatanaka, M. Shimoda, T. Hashimoto, Yusuke Yamamoto, Hideki Fujihara, W. Nishijima, Eikichi Tokunaga
The present report describes the treatment of 12 patients with primary mucosal malignant melanoma of the head and neck who visited our department between 2011 and 2017. There were 6 men and 6 women, aged 61-90 years （median, 76.5 years）, and the observation period was 7-165 months （median, 37 months）. Further, 11 patients （92％） presented with primary lesions located in the nasal/paranasal cavities and 1 patient （8％） with the primary lesion located in the oral cavity. The 3-year overall survival rate, as assessed using the Kaplan-Mei-er method, was 56％. Among 8 patients with primary malignant melanoma of the nasal/paranasal cavities who underwent carbon-ion radiotherapy or surgery as a radical treatment, the 3-year local control and 3-year recur-rence-free survival rates were 56％ and 38％, respectively. The local control rate was higher in the carbon-ion radiotherapy group. In 12 patients, the 5-year incidence of distant metastasis was as high as 75, and
{"title":"Mucosal malignant melanoma of the head and neck: Clinical analysis of 12 cases","authors":"Kazuhiro Mitsumura, M. Ōsaki, M. Hara, S. Kinoshita, Keitaro Nagano, Akio Hatanaka, M. Shimoda, T. Hashimoto, Yusuke Yamamoto, Hideki Fujihara, W. Nishijima, Eikichi Tokunaga","doi":"10.5981/jjhnc.46.365","DOIUrl":"https://doi.org/10.5981/jjhnc.46.365","url":null,"abstract":"The present report describes the treatment of 12 patients with primary mucosal malignant melanoma of the head and neck who visited our department between 2011 and 2017. There were 6 men and 6 women, aged 61-90 years （median, 76.5 years）, and the observation period was 7-165 months （median, 37 months）. Further, 11 patients （92％） presented with primary lesions located in the nasal/paranasal cavities and 1 patient （8％） with the primary lesion located in the oral cavity. The 3-year overall survival rate, as assessed using the Kaplan-Mei-er method, was 56％. Among 8 patients with primary malignant melanoma of the nasal/paranasal cavities who underwent carbon-ion radiotherapy or surgery as a radical treatment, the 3-year local control and 3-year recur-rence-free survival rates were 56％ and 38％, respectively. The local control rate was higher in the carbon-ion radiotherapy group. In 12 patients, the 5-year incidence of distant metastasis was as high as 75, and","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71242764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kiyofumi Sano, H. Fukushima, R. Kamiyama, H. Mitani
cancer, and conducted pre / post-operative instructions for those patients. During the pre-operative period, we observe and assess the patientʼs adherence to our instructions as well as their self-manage-ment capability for daily maintenance after TEP. During the post-operative instruction, it is important to teach the patient how to use a voice prosthesis cleaning brush to make sure they do not break the one-way valve of the Provox, which can easily happen. A clear and thorough explanation is also considered very important.
{"title":"Pre/Post-operative instruction for patients using ProvoxⓇ voice prosthesis","authors":"Kiyofumi Sano, H. Fukushima, R. Kamiyama, H. Mitani","doi":"10.5981/jjhnc.46.322","DOIUrl":"https://doi.org/10.5981/jjhnc.46.322","url":null,"abstract":"cancer, and conducted pre / post-operative instructions for those patients. During the pre-operative period, we observe and assess the patientʼs adherence to our instructions as well as their self-manage-ment capability for daily maintenance after TEP. During the post-operative instruction, it is important to teach the patient how to use a voice prosthesis cleaning brush to make sure they do not break the one-way valve of the Provox, which can easily happen. A clear and thorough explanation is also considered very important.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kiminobu Sato, T. Ono, Buichiro Shin, S. Chitose, H. Umeno
We reviewed patients with locally advanced squamous cell carcinoma of the tongue （LASCCT） treated by standard treatment modalities including irradiation followed by surgery （① RT ＋ surgery group）, surgery with-out neoadjuvant therapy （② surgery group）, and neoadjuvant chemotherapy followed by surgery （③ NAC ＋ surgery group）. No significant differences in 5-year locoregional control （LRC）, disease-free survival （DFS）, or overall survival （OS） rates were shown among the three groups. Furthermore, subgroup analysis by T, N, and clinical stage showed no significant differences of LRC, DFS, or OS among the three groups. The NAC ＋ surgery group tended to have much locoregional recurrence compared to the other groups, although no significant difference of rates of locoregional or distant recurrence was shown among the three groups. Furthermore, the NAC ＋ surgery group, including a higher proportion of advanced T or N stage, tended to have a lower proportion of distant recurrence and a favorable OS compared to the other groups. However, overall survival of the NAC ＋ surgery group was better even though the group included advanced T and N cases. There were some limita-tions of this study; further analysis is required for neoadjuvant therapy.
{"title":"Clinical analysis of locally advanced squamous cell carcinoma of the tongue along with the transition of neoadjuvant therapy","authors":"Kiminobu Sato, T. Ono, Buichiro Shin, S. Chitose, H. Umeno","doi":"10.5981/jjhnc.46.340","DOIUrl":"https://doi.org/10.5981/jjhnc.46.340","url":null,"abstract":"We reviewed patients with locally advanced squamous cell carcinoma of the tongue （LASCCT） treated by standard treatment modalities including irradiation followed by surgery （① RT ＋ surgery group）, surgery with-out neoadjuvant therapy （② surgery group）, and neoadjuvant chemotherapy followed by surgery （③ NAC ＋ surgery group）. No significant differences in 5-year locoregional control （LRC）, disease-free survival （DFS）, or overall survival （OS） rates were shown among the three groups. Furthermore, subgroup analysis by T, N, and clinical stage showed no significant differences of LRC, DFS, or OS among the three groups. The NAC ＋ surgery group tended to have much locoregional recurrence compared to the other groups, although no significant difference of rates of locoregional or distant recurrence was shown among the three groups. Furthermore, the NAC ＋ surgery group, including a higher proportion of advanced T or N stage, tended to have a lower proportion of distant recurrence and a favorable OS compared to the other groups. However, overall survival of the NAC ＋ surgery group was better even though the group included advanced T and N cases. There were some limita-tions of this study; further analysis is required for neoadjuvant therapy.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proposal for classification of surgery of parotid cancer","authors":"R. Kawata, M. Higashino, S. Nishikawa, T. Terada","doi":"10.5981/jjhnc.46.270","DOIUrl":"https://doi.org/10.5981/jjhnc.46.270","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masanobu Mizuta, K. Iwanaga, A. Yoshizawa, Shinichi Sato, H. Tamaki
This retrospective study investigated the treatment outcomes of patients with hypopharyngeal cancer. The study included 100 patients who were treated at our institution from August 2008 to July 2015. The three-year overall survival （OS） rates for Stage 0, Ⅰ, Ⅱ, Ⅲ, and Ⅳ were 100％, 68.6％, 100％, 56.3％, and 42.3％, respectively. An analysis of 82 patients who were treated curatively （median follow-up period: 37 months） revealed that T status was a significant factor for OS and disease-specific survival （DSS）; and N status was significant for DSS and distant metastasis-free survival. The sub-group analysis of the patients with Stage Ⅲ and Ⅳ disease showed that surgery and radiotherapy had comparable oncologic outcomes for T1 and T2 disease, whereas, for T3 and T4 disease, surgery had significantly improved outcome in OS and local control as compared to radiotherapy. Although some previous studies have reported that radiotherapy with concurrent chemotherapy had a comparable outcome to surgery even for advanced hypopharyngeal cancer, especially for T3 disease, the current results were inconsistent with those reports. The discrepancy might be caused by differences in the selection of patients for radiotherapy and in the amount of cumulative cisplatin dose in concurrent chemoradiotherapy.
{"title":"Treatment outcome of hypopharyngeal cancer: A single institutional experience","authors":"Masanobu Mizuta, K. Iwanaga, A. Yoshizawa, Shinichi Sato, H. Tamaki","doi":"10.5981/jjhnc.46.328","DOIUrl":"https://doi.org/10.5981/jjhnc.46.328","url":null,"abstract":"This retrospective study investigated the treatment outcomes of patients with hypopharyngeal cancer. The study included 100 patients who were treated at our institution from August 2008 to July 2015. The three-year overall survival （OS） rates for Stage 0, Ⅰ, Ⅱ, Ⅲ, and Ⅳ were 100％, 68.6％, 100％, 56.3％, and 42.3％, respectively. An analysis of 82 patients who were treated curatively （median follow-up period: 37 months） revealed that T status was a significant factor for OS and disease-specific survival （DSS）; and N status was significant for DSS and distant metastasis-free survival. The sub-group analysis of the patients with Stage Ⅲ and Ⅳ disease showed that surgery and radiotherapy had comparable oncologic outcomes for T1 and T2 disease, whereas, for T3 and T4 disease, surgery had significantly improved outcome in OS and local control as compared to radiotherapy. Although some previous studies have reported that radiotherapy with concurrent chemotherapy had a comparable outcome to surgery even for advanced hypopharyngeal cancer, especially for T3 disease, the current results were inconsistent with those reports. The discrepancy might be caused by differences in the selection of patients for radiotherapy and in the amount of cumulative cisplatin dose in concurrent chemoradiotherapy.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katsuji Asano, Yousuke Nagai, Y. Somekawa, M. Myoujin, Hikaru Ikeda, Masamichi Nisio, K. Takano
{"title":"Investigation of 71 cases of laryngeal preservation surgery of hypopharyngeal cancer","authors":"Katsuji Asano, Yousuke Nagai, Y. Somekawa, M. Myoujin, Hikaru Ikeda, Masamichi Nisio, K. Takano","doi":"10.5981/jjhnc.46.354","DOIUrl":"https://doi.org/10.5981/jjhnc.46.354","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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