Microchemical Journal最新文献

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Photocatalytic degradation of crystal violet dye using phytofabricated zinc oxide nanoparticles from anthocyanin extract

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal

Pub Date : 2025-04-17 DOI: 10.1016/j.microc.2025.113681

Sarla Yadav, Pooja Singh, Gunjan Varshney, Saurabh, Poonam Singh, Raminder Kaur

This study investigates a coprecipitation method for the production of zinc oxide nanoparticles (ZnO NPs) using anthocyanin (ATH) extract derived from red cabbage (RC) that acts as a reducing, capping and stabilising agent. The efficacy of these NPs in the photocatalytic degradation of crystal violet (CV) dye is assessed thoroughly considering all the relevant influencing parameters such as pH levels, catalytic dosage, and dye concentration, among others. The structural, morphological, surface charge and presence of different functional groups of the synthesized NPs were then analysed using XRD, SEM-EDX, BET, and FTIR. The average particle size of the synthesized ZnO NPs and ZnATH-(O) NPs was 31.12 nm and 27.91 nm, respectively. The BET analysis determined that the surface area of ZnO NPs was 15.685 m²/ g, and that of ZnATH-(O) NPs was 25.187 m²/ g. In contrast to ZnO NPs, ZnATH-(O) NPs exhibit efficient photocatalytic degradation of CV dye. This is due to their improved stability, reduced size, increased surface area and optimized structure. The influence of various parameters like initial dye concentration, catalyst dosage, pH and ionic strength was also assessed under 90 min visible light irradiation. It was observed that ZnATH-(O) NPs show maximum photocatalytic degradation of CV dye in 90 min of visible light irradiation with a degradation efficiency of 96.12 %. This green synthesis method mitigates the environmental consequences associated with conventional chemical synthesis and utilizes the plentiful and renewable resources present in RC, thereby offering a sustainable alternative to a deteriorating environment.

{"title":"Photocatalytic degradation of crystal violet dye using phytofabricated zinc oxide nanoparticles from anthocyanin extract","authors":"Sarla Yadav, Pooja Singh, Gunjan Varshney, Saurabh, Poonam Singh, Raminder Kaur","doi":"10.1016/j.microc.2025.113681","DOIUrl":"10.1016/j.microc.2025.113681","url":null,"abstract":"<div><div>This study investigates a coprecipitation method for the production of zinc oxidenanoparticles (ZnO NPs) usinganthocyanin (ATH)extract derived from red cabbage (RC) that acts as a reducing, capping and stabilising agent. The efficacy of these NPs in thephotocatalytic degradation of crystal violet (CV)dye is assessed thoroughly considering all the relevant influencing parameters such as pHlevels,catalyticdosage,anddyeconcentration, among others. The structural, morphological, surface charge and presence of different functional groups of the synthesized NPswere then analysed using XRD, SEM-EDX, BET, and FTIR. The average particle size of the synthesized ZnO NPs and ZnATH-(O) NPs was 31.12 nm and 27.91 nm, respectively. The BET analysis determined that the surface area of ZnO NPs was 15.685 m<sup>2</sup>/ g, and that of ZnATH-(O) NPs was 25.187 m<sup>2</sup>/ g. In contrast to ZnO NPs, ZnATH-(O) NPs exhibit efficient photocatalytic degradation of CV dye. This is due to their improved stability, reduced size, increased surface area and optimized structure. The influence of various parameters like initial dye concentration, catalyst dosage, pH and ionic strength was also assessed under 90 min visible light irradiation. It was observed that ZnATH-(O) NPs show maximum photocatalytic degradation of CV dye in 90 min of visible light irradiation with a degradation efficiency of 96.12 %. This green synthesis method mitigates the environmental consequences associated with conventional chemical synthesis andutilizes the plentiful and renewable resources present in RC, thereby offering a sustainable alternative to adeterioratingenvironment.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"213 ","pages":"Article 113681"},"PeriodicalIF":4.9,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143850283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep learning-based identification of drying methods and quality prediction of Dendrobium officinale

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal

Pub Date : 2025-04-17 DOI: 10.1016/j.microc.2025.113691

Guangyao Li , Zhili Duan , Yuanzhong Wang

Dendrobium officinale (D. officinale) possesses numerous active compounds with significant medicinal and nutritional potential. This work evaluates the potential of Fourier transform infrared (FTIR) and near infrared (NIR) spectroscopy combined with partial least squares discriminant analysis (PLS-DA), back-propagation neural network (BPNN), support vector machine (SVM), and residual convolutional neural network (ResNet) in identifying and classifying D. officinale from different drying methods. Furthermore, the Long Short-Term Memory Net (LSTM) and dry matter content (DMC) were employed to quantify the D. officinale DMC across various drying modalities. The deep learning model showed superior classification performance compared to the conventional machine learning model. Both the training and test datasets showed 100% accuracy for the ResNet model built using FTIR and NIR spectra. The Ratio of Performance Deviations (RPD) values of the LSTM regression models developed from raw FTIR and NIR spectra exceed 2. This work holds considerable practical importance for assessing the quality of D. officinale, optimizing processing, and ensuring the quality of market supply.

{"title":"Deep learning-based identification of drying methods and quality prediction of Dendrobium officinale","authors":"Guangyao Li , Zhili Duan , Yuanzhong Wang","doi":"10.1016/j.microc.2025.113691","DOIUrl":"10.1016/j.microc.2025.113691","url":null,"abstract":"<div><div><em>Dendrobium officinale</em> (<em>D. officinale</em>) possesses numerous active compounds with significant medicinal and nutritional potential. This work evaluates the potential of Fourier transform infrared (FTIR) and near infrared (NIR) spectroscopy combined with partial least squares discriminant analysis (PLS-DA), back-propagation neural network (BPNN), support vector machine (SVM), and residual convolutional neural network (ResNet) in identifying and classifying <em>D. officinale</em> from different drying methods. Furthermore, the Long Short-Term Memory Net (LSTM) and dry matter content (DMC) were employed to quantify the <em>D. officinale</em> DMC across various drying modalities. The deep learning model showed superior classification performance compared to the conventional machine learning model. Both the training and test datasets showed 100% accuracy for the ResNet model built using FTIR and NIR spectra. The Ratio of Performance Deviations (RPD) values of the LSTM regression models developed from raw FTIR and NIR spectra exceed 2. This work holds considerable practical importance for assessing the quality of <em>D. officinale</em>, optimizing processing, and ensuring the quality of market supply.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"213 ","pages":"Article 113691"},"PeriodicalIF":4.9,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143851623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in cyclodextrin-based materials: Anticancer and antimicrobial applications–A review (2021–2024)

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal

Pub Date : 2025-04-16 DOI: 10.1016/j.microc.2025.113672

Alaa Shafie , Amal Adnan Ashour

Cyclodextrins (CDs) have garnered significant interest in medicinal chemistry due to their ability to enhance the solubility, stability, and bioavailability of therapeutic agents. Their unique structural properties allow for the formation of inclusion complexes, which improve drug delivery efficiency and therapeutic outcomes. Recent advancements have demonstrated the dual potential of CDs in anticancer and antimicrobial applications, where they contribute to controlled drug release, reduced toxicity, and enhanced efficacy. By optimizing drug formulations, CDs play a crucial role in overcoming challenges associated with solubility-limited drugs, thereby supporting modern therapeutic approaches. This review explores the latest innovations in CD-based drug delivery, emphasizing their impact on both cancer treatment and antimicrobial strategies. With increasing research efforts dedicated to developing CD-based formulations, their role in healthcare continues to expand, offering new opportunities for improved drug design and patient outcomes.

引用次数: 0

Self-polymerization-driven high-purity hydrophobic carbon dots incorporated monolithic columns for high-selectivity reversed-phase capillary liquid chromatography

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal

Pub Date : 2025-04-16 DOI: 10.1016/j.microc.2025.113665

Dan Wang , Yuanmin Gong , Meiting Yan , Jiaqi Chen , Xueping Tao , Yang Zhou , Yan Ma , Li Rao , Panpan Chen , Qifeng Fu

Carbon dots (CDs) hold great potential for chromatographic separations. However, their application in chromatographic stationary phases has been limited by two major synthetic challenges: (1) insufficient control over surface chemoselectivity caused by impurity co-adsorption, and (2) structural heterogeneity arising from uncontrolled solvothermal byproducts. To address these limitations, we developed a self-polymerization-driven strategy to synthesize high-purity hydrophobic CDs from 8-amino-2-naphthol (8N2OH) and 2,3-dihydroxynaphthalene (DHN). These CDs were incorporated into organic polymer monoliths via in situ copolymerization, yielding novel 8N2OH-CDs and DHN-CDs hybrid monolithic stationary phases for reversed-phase capillary liquid chromatography. The synthesized CDs were thoroughly characterized, with high purity confirmed by proton nuclear magnetic resonance. The resulting monolithic columns exhibited high permeability and uniformity, as demonstrated by field emission scanning electron microscopy, attributed to the excellent dispersion of the CDs. The chromatographic performance was evaluated using nine types of neutral, alkaline, and acidic compounds, as well as Tanaka standard test mixtures. Compared to unmodified columns, the CD-modified monoliths showed significantly enhanced retention strength and selectivity, supported by Tanaka tests revealing multifactorial retention mechanisms. This work demonstrates the potential of high-purity hydrophobic CDs as versatile modifiers for high-performance chromatographic stationary phases.

{"title":"Self-polymerization-driven high-purity hydrophobic carbon dots incorporated monolithic columns for high-selectivity reversed-phase capillary liquid chromatography","authors":"Dan Wang , Yuanmin Gong , Meiting Yan , Jiaqi Chen , Xueping Tao , Yang Zhou , Yan Ma , Li Rao , Panpan Chen , Qifeng Fu","doi":"10.1016/j.microc.2025.113665","DOIUrl":"10.1016/j.microc.2025.113665","url":null,"abstract":"<div><div>Carbon dots (CDs) hold great potential for chromatographic separations. However, their application in chromatographic stationary phases has been limited by two major synthetic challenges: (1) insufficient control over surface chemoselectivity caused by impurity co-adsorption, and (2) structural heterogeneity arising from uncontrolled solvothermal byproducts. To address these limitations, we developed a self-polymerization-driven strategy to synthesize high-purity hydrophobic CDs from 8-amino-2-naphthol (8N2OH) and 2,3-dihydroxynaphthalene (DHN). These CDs were incorporated into organic polymer monoliths via in situ copolymerization, yielding novel 8N2OH-CDs and DHN-CDs hybrid monolithic stationary phases for reversed-phase capillary liquid chromatography. The synthesized CDs were thoroughly characterized, with high purity confirmed by proton nuclear magnetic resonance. The resulting monolithic columns exhibited high permeability and uniformity, as demonstrated by field emission scanning electron microscopy, attributed to the excellent dispersion of the CDs. The chromatographic performance was evaluated using nine types of neutral, alkaline, and acidic compounds, as well as Tanaka standard test mixtures. Compared to unmodified columns, the CD-modified monoliths showed significantly enhanced retention strength and selectivity, supported by Tanaka tests revealing multifactorial retention mechanisms. This work demonstrates the potential of high-purity hydrophobic CDs as versatile modifiers for high-performance chromatographic stationary phases.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"213 ","pages":"Article 113665"},"PeriodicalIF":4.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143839387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An anti-fouling photoelectrochemical immunosensor based on zwitterionic peptide and Z-scheme PEDOT/ZnIn2S4 heterojunction for highly sensitive detection of Aβ40

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal

Pub Date : 2025-04-16 DOI: 10.1016/j.microc.2025.113677

Ximei Hu , Xiaoqi Chen , Jinlan Li , Jiawei Zhou , Xiaohua Zhu , Meiling Liu , Ying Liu , Youyu Zhang , Yang Liu

Amyloid-beta peptide (Aβ) is considered a promising biomarker for the diagnosis of Alzheimer’s disease (AD). Herein, we developed an anti-fouling photoelectrochemical (PEC) immunosensor for sensitive Aβ40 detection based on Z-scheme heterojunction poly (3,4-ethylenedioxythiophene) (PEDOT)/ZnIn₂S₄ and zwitterionic peptide. Due to the excellent electrical conductivity of PEDOT, the Z-scheme PEDOT/ZnIn₂S₄ heterojunction exhibited a high photocurrent response, which can promote the separation and transfer of photogenerated electron/hole pairs. The zwitterionic peptide with hydrophilicity and electrical neutrality was used as a blocking agent to reduce nonspecific adsorption. The proposed PEC immunosensor showed outstanding performance for Aβ40 with high selectivity, stability, wide liner range (from 10 pg mL⁻¹ to 5 ng mL⁻¹), and a low detection limit (4.7 pg mL⁻¹). Moreover, the integration strategy of heterojunction with zwitterionic peptide provides a promising way for protein detection in practical applications.

{"title":"An anti-fouling photoelectrochemical immunosensor based on zwitterionic peptide and Z-scheme PEDOT/ZnIn2S4 heterojunction for highly sensitive detection of Aβ40","authors":"Ximei Hu , Xiaoqi Chen , Jinlan Li , Jiawei Zhou , Xiaohua Zhu , Meiling Liu , Ying Liu , Youyu Zhang , Yang Liu","doi":"10.1016/j.microc.2025.113677","DOIUrl":"10.1016/j.microc.2025.113677","url":null,"abstract":"<div><div>Amyloid-beta peptide (Aβ) is considered a promising biomarker for the diagnosis of Alzheimer’s disease (AD). Herein, we developed an anti-fouling photoelectrochemical (PEC) immunosensor for sensitive Aβ40 detection based on Z-scheme heterojunction poly (3,4-ethylenedioxythiophene) (PEDOT)/ZnIn<sub>2</sub>S<sub>4</sub> and zwitterionic peptide. Due to the excellent electrical conductivity of PEDOT, the Z-scheme PEDOT/ZnIn<sub>2</sub>S<sub>4</sub> heterojunction exhibited a high photocurrent response, which can promote the separation and transfer of photogenerated electron/hole pairs. The zwitterionic peptide with hydrophilicity and electrical neutrality was used as a blocking agent to reduce nonspecific adsorption. The proposed PEC immunosensor showed outstanding performance for Aβ40 with high selectivity, stability, wide liner range (from 10 pg mL<sup>−1</sup> to 5 ng mL<sup>−1</sup>), and a low detection limit (4.7 pg mL<sup>−1</sup>). Moreover, the integration strategy of heterojunction with zwitterionic peptide provides a promising way for protein detection in practical applications.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"213 ","pages":"Article 113677"},"PeriodicalIF":4.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143847772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving room-temperature ammonia sensing properties of CH3NH3PbI3-based gas sensors via coordination interaction using monoethanolamine ligand

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal

Pub Date : 2025-04-16 DOI: 10.1016/j.microc.2025.113649

Bowen Zhang , Fei Cheng , Zeyu Sun , Kunpeng Xing , Bo Zhang , Saisai Zhang , Hari Bala , Yan Wang

Organic-inorganic hybrid perovskite materials have garnered significant research interest owing to their exceptional crystallographic characteristics and remarkable optoelectronic properties. This study presents a breakthrough in room-temperature ammonia sensing through the rational design of CH₃NH₃PbI₃ (MAPbI₃)-based chemiresistive sensors modified with monoethanolamine (MEA) ligands. By integrating MEA as a coordination agent into the perovskite precursor solution, we achieved controlled crystallization dynamics, yielding compact MAPbI₃ films with unique maple-leaf grain morphology and enhanced humidity resistance. The optimized TiO₂/MEA-MAPbI₃ sensor exhibited a nearly 2.1-fold improvement in response amplitude toward 100 ppm NH₃ compared to unmodified counterparts, alongside exceptional selectivity to NH₃ against interfering gases. Crucially, MEA-derived (PbI₂)-MEA-(MAI) molecular shielding layers at grain boundaries suppressed moisture-induced degradation, enabling stable operation in air environment (∼30 %RH) with less than 22 % response degradation over 29 days. Mechanistic analyses revealed that the sensing behavior originates from reversible cation exchange between methylammonium (MA⁺) and ammonium (NH₄⁺) species at the perovskite surface, corroborated by density functional theory (DFT) calculations showing preferential NH₃ adsorption over other analyte gases.

有机-无机杂化包晶材料因其特殊的晶体学特征和显著的光电特性而备受研究关注。本研究通过合理设计用单乙醇胺（MEA）配体修饰的基于 CH3NH3PbI3（MAPbI3）的化学电阻传感器，在室温氨传感领域取得了突破性进展。通过在过氧化物前驱体溶液中加入 MEA 作为配位剂，我们实现了可控的结晶动力学，制备出具有独特枫叶晶粒形态的紧凑型 MAPbI3 薄膜，并增强了耐湿性。优化后的 TiO2/MEA-MAPbI3 传感器对 100 ppm NH3 的响应幅度比未改性的同类产品提高了近 2.1 倍，同时对 NH3 的选择性也优于干扰气体。最重要的是，晶界上的 MEA 衍生 (PbI2)-MEA-(MAI) 分子屏蔽层抑制了湿气引起的降解，使其能够在空气环境（30%RH）中稳定工作，29 天的响应降解率低于 22%。机理分析表明，这种传感行为源于过氧化物表面的甲基铵（MA+）和铵（NH4+）物种之间的可逆阳离子交换，密度泛函理论（DFT）计算也证实了这一点，计算显示 NH3 比其他分析气体具有优先吸附性。

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引用次数: 0

Comprehensive evaluation of peptides quality using a “quantity-activity integration” approach with a portable NIR spectrometer and entropy weighted TOPSIS method: A case study in sea cucumber peptides

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal

Pub Date : 2025-04-16 DOI: 10.1016/j.microc.2025.113673

Huisha Huang , Ziwei Zou , Ying Yang , Liuyan Wei , Xin Mao , Yiwen Shou , Qinpei Lu , Chao Feng , Yu Ye , Ziyan Huang , Hongwei Guo , Zhiheng Su , Zhaoquan Huang

Peptides are highly valued for their nutritional benefits, yet most current evaluation methods focus solely on peptide content or specific bioactivities. In this study, we introduce a novel “quantity-activity integration” approach that combines a portable near-infrared (NIR) spectrometer with the entropy weight TOPSIS method for a comprehensive assessment of peptide quality. Using sea cucumber peptides (SCP) as a model, we integrated chemometric techniques with NIR spectroscopy to successfully predict both peptide content and antioxidant activity. The top-performing prediction models demonstrated strong predictive power, with a residual prediction deviation above 2.2 and a correlation coefficient exceeding 0.9. The entropy weight TOPSIS method was then used to rank SCP quality based on these predicted values. For the highest-ranked SCP, amino acid nutritional evaluation was also performed. This integrated approach provides a valuable tool for the comprehensive evaluation of peptide quality.

{"title":"Comprehensive evaluation of peptides quality using a “quantity-activity integration” approach with a portable NIR spectrometer and entropy weighted TOPSIS method: A case study in sea cucumber peptides","authors":"Huisha Huang , Ziwei Zou , Ying Yang , Liuyan Wei , Xin Mao , Yiwen Shou , Qinpei Lu , Chao Feng , Yu Ye , Ziyan Huang , Hongwei Guo , Zhiheng Su , Zhaoquan Huang","doi":"10.1016/j.microc.2025.113673","DOIUrl":"10.1016/j.microc.2025.113673","url":null,"abstract":"<div><div>Peptides are highly valued for their nutritional benefits, yet most current evaluation methods focus solely on peptide content or specific bioactivities. In this study, we introduce a novel “quantity-activity integration” approach that combines a portable near-infrared (NIR) spectrometer with the entropy weight TOPSIS method for a comprehensive assessment of peptide quality. Using sea cucumber peptides (SCP) as a model, we integrated chemometric techniques with NIR spectroscopy to successfully predict both peptide content and antioxidant activity. The top-performing prediction models demonstrated strong predictive power, with a residual prediction deviation above 2.2 and a correlation coefficient exceeding 0.9. The entropy weight TOPSIS method was then used to rank SCP quality based on these predicted values. For the highest-ranked SCP, amino acid nutritional evaluation was also performed. This integrated approach provides a valuable tool for the comprehensive evaluation of peptide quality.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"213 ","pages":"Article 113673"},"PeriodicalIF":4.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143851622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A highly sensitive electrochemical detection of multiple heavy metal ions in water using PAni–RYFG/GCE modified electrode: Experimental and DFT studies

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal

Pub Date : 2025-04-16 DOI: 10.1016/j.microc.2025.113654

Muniyasamy Maheshwaran, Konda Kannan Satheesh Kumar

Here, we report the individual and simultaneous detection of Hg²⁺ and Pb²⁺ ions sensor constructed by a novel polyaniline-yellow 42 dye (PAni-RYFG) composite with the combination of reactive yellow 42 dye (RYFG) moiety and dedoped polyaniline (DD PAni) using chemical oxidative polymerization method. The developed sensor’s morphology and chemical composition were analyzed using various spectroscopic techniques. Further, to serve as an electrochemical interface for sensing Hg²⁺ and Pb²⁺ ions, the PAni-RYFG composite was drop cast on the surface of the glassy carbon electrode (GCE). The electrochemical behavior of the electrode modifiers was studied using the CV and EIS studies. The electrode modifiers’ sensing ability and electrochemical catalytic activity were analyzed using the differential pulse voltammetry (DPV) technique in an acetate buffer solution with varied pH levels, individually and concurrently. PAni-RYFG/GCE electrode was shown to have a strong electrochemical response and outstanding electrocatalytic activity for the distinctive identification of Hg²⁺ and Pb²⁺ ions from other heavy metal ions in concentrations ranging from 1 to 21 μM, the detection limits (S/N = 3) were 2 and 6.2 nM, respectively. The selectivity of PAni-RYFG/GCE was examined based on the influence of interfering agents on the signals of the targeted metal ions. Likewise, the applicability of the DPV was checked in real water samples. Interestingly, the recovery percentages above 100 % for all water samples evidenced the authenticity of PAni-RYFG/GCE for Hg²⁺ and Pb²⁺ ions determination in real water samples. Density Functional Theory (DFT) determined the proposed sensors’ adsorption process.

{"title":"A highly sensitive electrochemical detection of multiple heavy metal ions in water using PAni–RYFG/GCE modified electrode: Experimental and DFT studies","authors":"Muniyasamy Maheshwaran, Konda Kannan Satheesh Kumar","doi":"10.1016/j.microc.2025.113654","DOIUrl":"10.1016/j.microc.2025.113654","url":null,"abstract":"<div><div>Here, we report the individual and simultaneous detection of Hg<sup>2+</sup> and Pb<sup>2+</sup> ions sensor constructed by a novel polyaniline-yellow 42 dye (PAni-RYFG) composite with the combination of reactive yellow 42 dye (RYFG) moiety and dedoped polyaniline (DD PAni) using chemical oxidative polymerization method. The developed sensor’s morphology and chemical compositionwere analyzed using various spectroscopic techniques. Further, to serve as an electrochemical interface for sensing Hg<sup>2+</sup> and Pb<sup>2+</sup> ions, the PAni-RYFG composite was drop cast on the surface of the glassy carbon electrode (GCE). The electrochemical behavior of the electrode modifiers was studied using the CVand EIS studies. The electrode modifiers’ sensing ability and electrochemical catalytic activity were analyzed using the differential pulse voltammetry (DPV) technique in an acetate buffer solution with varied pH levels, individually and concurrently. PAni-RYFG/GCE electrode was shown to have a strong electrochemical response and outstanding electrocatalytic activity for the distinctive identification of Hg<sup>2+</sup> and Pb<sup>2+</sup> ions from other heavy metal ions in concentrations ranging from 1 to 21 μM, the detection limits (S/N = 3) were 2 and 6.2 nM, respectively. The selectivity of PAni-RYFG/GCE was examined based on the influence of interfering agents on the signals of the targeted metal ions. Likewise, the applicability of the DPV was checked in real water samples. Interestingly, the recovery percentages above 100 % for all water samples evidenced the authenticity of PAni-RYFG/GCE for Hg<sup>2+</sup> and Pb<sup>2+</sup> ions determination in real water samples. Density Functional Theory (DFT) determined the proposed sensors’ adsorption process.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"213 ","pages":"Article 113654"},"PeriodicalIF":4.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143850279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ppt level gas sensing by resistive gas Sensors: A review

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal

Pub Date : 2025-04-16 DOI: 10.1016/j.microc.2025.113670

M. Hjiri , N. Benmansour , N.H. Alonizan , G. Neri

Resistive sensors are highly popular sensors for the detection of toxic gases. This is mainly related to their high response, stability, compactness, low price and swift dynamics. In particular, most of them are able to detect toxic gases in ppm and ppb range. However, there are some reports about ppt level detection of gases by resistive gas sensors, a very low level close to capability of a trained dog. This feature is very important for increase of safety of our life and higher standards of life. In this review paper, for the first time we have discussed various sensing materials with ppt detection of gases. Mechanisms of gas detection are explained in detail. We believe that present review paper provides plenty of useful information for the researchers work in this interdisciplinary field.

引用次数: 0

Optimized essential oil extraction method based on salt solution-enhanced homogenization pretreatment and microwave extraction for Kaempferia galanga L

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal

Pub Date : 2025-04-16 DOI: 10.1016/j.microc.2025.113661

Qingfen Zhang , Chenglin Li , Shengcheng Mi , Xiaojie Xu , Zhiqiang He , Lin Wang , Zhonghua Tang , Qi Lu

The primary purpose of this study is to develop a highly efficient extraction method to meet the growing demand for Kaempferia galanga essential oil (KGEO) in various industries. In this study, an innovative approach for extracting essential oil from fresh K. galanga rhizomes using salt solution-enhanced homogenization pretreatment and microwave extraction (HP-SOME) was proposed. A kinetic study was conducted on the extraction process of essential oil. The key factors were screened using the Plackett–Burman Design and optimized using the Box-Behnken Design. Under the optimization parameters: sodium chloride concentration of 1.5 %, microwave power of 475 W, and microwave time of 23 min, the actual yield was 5.26 ± 0.10 %. The HP-SOME method exhibited a significant increase of 58.91 % in essential oil yield compared to that of the hydrodistillation method (3.31 ± 0.10 %). In addition, the composition of the KGEO was determined using Fourier transform infrared spectroscopy, Raman spectroscopy, and gas chromatography-mass spectrometry. The KGEO obtained by HP-SOME had a 6.26 % increase in the main component ethyl p-methoxycinnamate and a 4.13 % increase in ethyl cinnamate compared to that obtained by the HD method. Investigations into antimicrobial activity revealed that KGEO extracted by the HP-SOME method exhibited superior and more comprehensive antimicrobial characteristics. In conclusion, the HP-SOME method demonstrated remarkable capabilities in obtaining KGEO with notable efficiency, yield, and quality. This method holds great promise in the field of essential oil extraction.

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