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2007 Computers in Cardiology最新文献

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3D heart segmentation and volumetry using deformable shape models 使用可变形形状模型的3D心脏分割和体积测量
Pub Date : 2007-09-01 DOI: 10.1109/CIC.2007.4745592
T. Schwarz, T. Heimann, I. Wolf, H. Meinzer
Segmentation using deformable model-based approaches has become a common application in 3D medical image analysis, as it provides a fast and robust method to detect structures, e.g. organs, fully-automated after initialization. However, some earlier approaches in some cases did not converge in the segmentation process even on rather good datasets or showed major variations in the segmentation results. This work presents the application of a shape model enhanced with the possibility of free deformation with respect to local grey value distributions, used to automatically detect the end-diastolic and end-systolic left heart ventricle (LV) in 3D MRI images after a short user interaction, thus to calculate the heart stroke volume.
使用基于可变形模型的方法进行分割已成为3D医学图像分析中的一种常见应用,因为它提供了一种快速且鲁棒的方法来检测结构,例如器官,在初始化后完全自动化。然而,在某些情况下,一些早期的方法在分割过程中甚至在相当好的数据集上也没有收敛,或者在分割结果中显示出很大的差异。这项工作提出了一种形状模型的应用,增强了相对于局部灰色值分布的自由变形的可能性,用于在短暂的用户交互后自动检测3D MRI图像中的舒张末期和收缩末期左心室(LV),从而计算心脏搏量。
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引用次数: 16
Measurements standards and test signals in QRS boundary determination QRS边界确定中的测量标准和测试信号
Pub Date : 2007-09-01 DOI: 10.1109/CIC.2007.4745518
S. Hargittai
The most important step of quantitative ECG analysis is to determine the wave boundaries. The main objectives of this paper are to consider the scope and the limitations of using CSE databases and standard test signals for evaluation and improvement of ECG wave recognition programs. Three databases were used for evaluating the ECG measurement programs. The databases were not only used for automatic assessment but all records and channels were checked individually and deviations from the references were analyzed. The CSE databases and the standard analytical ECG curves can be used for automatic evaluation of an ECG measurement program, but reference data should be used with care. Design engineers have to have appropriate knowledge in both the signal-processing field and electrocardiography.
心电定量分析最重要的一步是确定波边界。本文的主要目的是考虑使用CSE数据库和标准测试信号来评估和改进心电波识别程序的范围和局限性。三个数据库用于评估心电图测量程序。数据库不仅用于自动评估,而且对所有记录和渠道进行单独检查,并分析与参考文献的偏差。CSE数据库和标准分析心电曲线可用于心电测量程序的自动评估,但参考数据应谨慎使用。设计工程师必须在信号处理领域和心电图学方面都有适当的知识。
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引用次数: 2
Wavefront detection from intra-atrial recordings 心房内记录的波前检测
Pub Date : 2007-09-01 DOI: 10.1109/CIC.2007.4745430
U. Richter, M. Stridh, D. Husser, D. Cannom, A. Bhandari, A. Bollmann, L. Sornmo
The present study deals with detection of intra-atrial wavefronts from atrial activation times in adjacent bipolar electrograms. A statistic of the delays within each wave-front was calculated and served as a basis for quantifying the wavefront consistency as well as the propagation of the electrical activity along the catheter. The database consisted of 19 patients for which five electrograms were recorded simultaneously during 10 s. The analysis resulted in 38plusmn2 complete wavefronts per patient, i.e., wavefronts consisting of one activation from each recording site. Two parameters were evaluated for quantifying wavefront consistency, which together with the propagation profile well reflect the overall wavefront timing. In most cases, electrical activity was observed first in the high septal right atrium, and then spread along the catheter.
本研究涉及检测心房内波阵面从心房激活时间相邻双极电图。计算每个波前的延迟统计,并作为量化波前一致性以及沿导管传播的电活动的基础。数据库包括19例患者,在10 s内同时记录5个心电图。分析结果显示,每个患者有38plusmn2个完整的波前,即每个记录位点都有一个激活的波前。两个参数用于量化波前一致性,它们与传播剖面一起很好地反映了整体波前时序。在大多数病例中,电活动首先在高间隔右心房观察到,然后沿着导管扩散。
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引用次数: 2
Comparison of P wave durations as assessed with the bipolar and unipolar atrial intracardiac electrograms: Applicability to QuickOpt™ 与双极和单极心房心内电图评估的P波持续时间的比较:适用于QuickOpt™
Pub Date : 2007-09-01 DOI: 10.1109/CIC.2007.4745600
X. Min, P. Demers, D. Muller, J. Snell, P. Levine, E. Ostrow
Studies have shown that inter-atrial conduction time (IACT) can be used to estimate optimal PV delays. QuickOpt utilizes the atrial EGM (AEGM) and measures P-wave duration (PW) to estimate the IACT. This study compares PW between bipolar (Bi) and unipolar (Uni) AEGMs in patients with either a pacemaker (PP) or a CRT-D pulse generator. Bipolar (Bi) and Unipolar (Uni) AEGMs were obtained from 42 PP and 18 CRT-D pts. In the PP, PWs associated with Bi and Uni AEGMs were close (114plusmn19 ms vs. 110plusmn20 ms). Intra-patient difference was 3.9plusmn8.7 ms, and the 95% confidence interval for the difference was (1.2, 6.6). With CRT-D, PWs were 79plusmn18.4 ms and 81plusmn14 ms for Bi and Uni sensing and the intra-patient difference was -1.2plusmn14.9 ms. In 18 PP, the difference between ECG and either bipolar or unipolar PW was 4.8plusmn17.8 ms and 0.9 ms plusmn 15.5 ms respectively. PWs were similar between unipolar AEGMs, bipolar AEGMs, and surface ECG.
研究表明,房间传导时间(IACT)可用于估计最佳PV延迟。QuickOpt利用心房EGM (AEGM)和测量p波持续时间(PW)来估计IACT。本研究比较了使用起搏器(PP)或CRT-D脉冲发生器的患者双极(Bi)和单极(Uni) egms的PW。从42名PP和18名CRT-D患者中获得双极(Bi)和单极(Uni) egms。在PP中,与Bi和Uni AEGMs相关的PWs接近(114plusmn19 ms vs. 110plusmn20 ms)。患者内差异为3.9±8.7 ms,差异的95%置信区间为(1.2,6.6)。ct - d检测Bi和Uni的PWs分别为79plusmn18.4 ms和81plusmn14 ms,患者内差异为-1.2plusmn14.9 ms。在18pp时,心电图与双极或单极PW的差异分别为4.8 ms + 17.8 ms和0.9 ms + 15.5 ms。单极心电图、双极心电图和体表心电图的PWs相似。
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引用次数: 0
An efficient technique for determining the steady-state membrane potential profile in tissues with multiple cell types 一种测定多种细胞类型组织中稳态膜电位分布的有效技术
Pub Date : 2007-09-01 DOI: 10.1109/CIC.2007.4745434
V. Jacquemet, C. Henriquez
Most simulations of cardiac electrophysiology use the steady state as initial condition. Spatial variations in steady-state membrane potential may arise due to ischemia, coupling with fibroblasts, or local changes in intrinsic resting potential. In large scale models, simulating free evolution until the steady-state is reached may be computationally expensive when long time constants or slow concentration drifts are involved in the cell models. This paper describes a dedicated Newton-based root-finding solver to determine the steady state of a tissue in which two or more cell types coexist in the monodomain framework. This approach was applied to a 2D microstructural tissue model in which myocytes were coupled to fibroblasts, leading to an inhomogeneous elevation of the myocyte resting potential.
大多数心脏电生理模拟使用稳态作为初始条件。稳态膜电位的空间变化可能是由于缺血、与成纤维细胞耦合或内在静息电位的局部变化引起的。在大尺度模型中,当细胞模型中涉及长时间常数或缓慢浓度漂移时,模拟自由进化直到达到稳态可能会造成计算上的昂贵。本文描述了一个专用的基于牛顿的寻根求解器,用于确定在单域框架中两种或两种以上细胞类型共存的组织的稳态。该方法应用于二维微结构组织模型,其中肌细胞与成纤维细胞偶联,导致肌细胞静息电位不均匀升高。
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引用次数: 4
Body surface potential mapping for detection of myocardial infarct sites 体表电位映射检测心肌梗死部位
Pub Date : 2007-09-01 DOI: 10.1109/CIC.2007.4745451
Piotr Zarychta, Fiona E. Smith, S. King, A. J. Haigh, A. Klinge, Dingchang Zheng, S. Stevens, John F. Allen, A. Okelarin, Philip Langley, Alan Murray
Using the additional information from multi-lead body surface potential recordings we aimed to study ECG features to predict the extent of infarcted myocardium as part of the 2007 PhysioNet/Computers in Cardiology Challenge. We studied potential and QT maps through key stages of the ventricular cycle assessing the 2 training and 2 test cases. Clinical assessment of the ECGs was provided by three cardiologists. QRS axis was abnormal in training case 1. ST was elevated in training case 1 and test case 2. T wave axis was abnormal in training case 2 and test case 1. T wave axis was different to QRS axis in training case 1. Cardiologists agreed that training cases 1 and 2 were anterior and inferior infarctions respectively, while they considered both test cases to be normal variations. The maps, however, showed significant abnormalities in the test cases.
利用多导联体表电位记录的附加信息,我们旨在研究心电图特征,以预测梗死心肌的范围,这是2007年生理学网络/心脏病学计算机挑战赛的一部分。我们通过心室周期的关键阶段研究了电位和QT图,评估了2个训练病例和2个测试病例。心电图的临床评估由三位心脏病专家提供。训练病例1 QRS轴异常。ST在训练用例1和测试用例2中升高。训练用例2和测试用例1 T波轴异常。训练病例1的T波轴与QRS轴不同。心脏病专家一致认为,训练病例1和2分别是前梗死和下梗死,而他们认为两个测试病例都是正常变异。然而,地图在测试用例中显示了显著的异常。
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引用次数: 28
Changes in RR and QT intervals after spontaneous and respiratory arousal in patients with obstructive sleep apnea 阻塞性睡眠呼吸暂停患者自发觉醒和呼吸觉醒后RR和QT间期的变化
Pub Date : 2007-09-01 DOI: 10.1109/CIC.2007.4745576
M. Baumert, J. Smith, P. Catcheside, D. McEvoy, D. Abbott, E. Nalivaiko
Obstructive sleep apnea (OSA) is a common disorder that has been associated with hypertension and ventricular arrhythmias. The aim of this study was to investigate changes in RR and QT intervals after respiratory and spontaneous arousals in patients with OSA. We conducted overnight sleep studies in 20 patients. The mean and range of respiratory disturbance index were 49 plusmn 28 and respectively. During stage 2 sleep, ECGs were analyzed over a period of 30 seconds. From the 187 arousals investigated (120 respiratory vs. 67 spontaneous) a significant number were associated with a RR interval shortening (64%). Eighteen percent of the RR intervals were prolonged, with a significantly higher number during spontaneous arousals (13% vs. 27%). Similarly, QT intervals shortened after arousal (65%). But there were no significant differences between spontaneous and respiratory arousals. In conclusion, spontaneous and respiratory arousals lead to changes in heart rate and ventricular repolarization.
阻塞性睡眠呼吸暂停(OSA)是一种常见的疾病,与高血压和室性心律失常有关。本研究的目的是探讨OSA患者呼吸和自发觉醒后RR和QT间期的变化。我们对20个病人进行了夜间睡眠研究。呼吸障碍指数的平均值为49,范围为28。在第二阶段睡眠中,在30秒的时间内分析心电图。在调查的187次唤醒中(120次呼吸性对67次自发性),大量唤醒与RR间期缩短相关(64%)。18%的RR间隔时间延长,自发觉醒期间的RR间隔时间明显增加(13%对27%)。同样,觉醒后QT间期缩短(65%)。自发觉醒和呼吸觉醒之间无显著差异。综上所述,自发性和呼吸性觉醒导致心率和心室复极的变化。
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引用次数: 8
Assessment of factors affecting accuracy and repeatability in semi-automated echocardiographic measurement of chamber volume using a physical phantom 利用物理假体半自动化超声心动图测量心室容积影响准确性和可重复性的因素评估
Pub Date : 2007-09-01 DOI: 10.1109/CIC.2007.4745424
J. Wild, A. Sims, J. Pemberton, A. Kenny, A. Murray
Three dimensional echocardiography offers the benefit of non-invasive measurement of chamber volume at the cost of increased effort of data handling. Automated or semi-automated image analysis may help to reduce manual effort but can embody assumptions and limitations which have a significant effect on results.
三维超声心动图以增加数据处理的工作量为代价,提供了无创测量腔容量的好处。自动化或半自动化图像分析可能有助于减少人工工作,但可能包含对结果有重大影响的假设和限制。
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引用次数: 0
Study of the dynamic relationship between T wave morphology and heart rate during ischemia 缺血时T波形态与心率动态关系的研究
Pub Date : 2007-09-01 DOI: 10.1109/CIC.2007.4745480
F. Simon, P. Laguna, E. Pueyo
In this work the relationship between heart rate and several repolarization indices, including the QT interval and T wave morphology descriptors, has been investigated. A time-variant model has been proposed to describe the Ir to RR relationship, with Ir generically denoting one of the repolarization indices under study, and RR the running mean RR interval. The proposed methodology is applied to the analysis of stress test recordings. Three different groups of individuals are considered: ischemic patients, low-risk patients and healthy subjects. It is shown that the slope of the line fitting the Ir to RR beat series evaluated at stress peak is significantly lower in ischemic patients as compared to low-risk patients and healthy subjects, and that result is valid for any of the Ir indices. It can be concluded that loss of the T wave adaptation capability (lower slope) to heart rate changes, measured at stress test peak, is related of the presence of ischemia.
本文研究了心率与若干复极指数(包括QT间期和T波形态描述符)之间的关系。提出了一个时变模型来描述Ir - RR关系,Ir一般表示研究的复极化指标之一,RR表示运行平均RR区间。所提出的方法应用于压力测试记录的分析。考虑了三种不同的个体群体:缺血性患者、低风险患者和健康受试者。结果表明,与低危患者和健康受试者相比,缺血患者在应激峰值时评估的Ir - RR心率序列拟合线的斜率明显较低,并且该结果对任何Ir指标都有效。由此可见,在应激测试峰值测量心率变化时T波适应能力(下斜率)的丧失与缺血的存在有关。
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引用次数: 4
Cellular phone based online ECG processing for ambulatory and continuous detection 基于手机的在线心电处理,实现动态连续检测
Pub Date : 2007-09-01 DOI: 10.1109/CIC.2007.4745570
X. Chen, C.T. Ho, E. Lim, T.Z. Kyaw
A cellular phone based online ECG processing system for ambulatory and continuous detection has been developed. It aids cardiovascular disease (CVD) patients to monitor their heart status and detect abnormalities in their normal daily life. This system is a solution to supplement the limitations in conventional clinic examination such as the difficulty in capturing rare events, off-hospital monitoring of patientspsila heart status and the immediate dissemination of physicianpsilas instruction to the patients.
开发了一种基于手机的动态连续检测在线心电处理系统。它帮助心血管疾病(CVD)患者监测他们的心脏状况,并在日常生活中发现异常情况。该系统解决了常规临床检查难以捕捉罕见事件、院外监测患者心脏状态、及时向患者传达医生指导等局限性。
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引用次数: 57
期刊
2007 Computers in Cardiology
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