To research how long-term positive airway pressure (PAP) therapy affects the severity of restless legs syndrome in patients with obstructive sleep apnea syndrome (OSASThe study included 320 individuals that were diagnosed with moderate and severe OSAS using polysomnography (PSG) and under PAP treatment. Among these patients, the demographic data of 72 patients who met the diagnostic criteria of restless legs syndrome (RLS) were analyzed. The patients were evaluated with the International RLS Study Group rating scale (IRLS) before and at the 12th month after PAP in the treatment of OSAS. The mean body mass index of the 72 patients with OSAS and RLS was 31.2 (±5.8), and their mean apnea-hypopnea index was 44.9±27.7. The prevalence of RLS in moderate and severe OSAS was 24%. There was a negative correlation between the IRLS score and mean oxygen saturation all night (r: -0.075), minimum oxygen saturation all night (r: -0.125), time spent below <90% saturation (r: -0.172), and sleep efficiency (r: 0.087) on PSG performed before PAP treatment, as well as a negative correlation between the IRLS score and weekly PAP use hours at the 12th month after PAP treatment (r: -0.316; p<0.001). The data obtained from this study suggest that the coexistence of OSAS and RLS is common and should not be overlooked in the diagnosis of comorbid diseases. Long-term PAP treatment is effective in reducing RLS symptoms. Further studies are needed on this subject.
{"title":"Long-Term Effects of Positive Airway Pressure Treatment on Restless Legs Syndrome Severity in Obstructive Sleep Apnea Syndrome","authors":"Gülşah YAŞA ÖZTÜRK, S. Berik Safçi","doi":"10.20515/otd.1233819","DOIUrl":"https://doi.org/10.20515/otd.1233819","url":null,"abstract":"To research how long-term positive airway pressure (PAP) therapy affects the severity of restless legs syndrome in patients with obstructive sleep apnea syndrome (OSASThe study included 320 individuals that were diagnosed with moderate and severe OSAS using polysomnography (PSG) and under PAP treatment. Among these patients, the demographic data of 72 patients who met the diagnostic criteria of restless legs syndrome (RLS) were analyzed. The patients were evaluated with the International RLS Study Group rating scale (IRLS) before and at the 12th month after PAP in the treatment of OSAS. The mean body mass index of the 72 patients with OSAS and RLS was 31.2 (±5.8), and their mean apnea-hypopnea index was 44.9±27.7. The prevalence of RLS in moderate and severe OSAS was 24%. There was a negative correlation between the IRLS score and mean oxygen saturation all night (r: -0.075), minimum oxygen saturation all night (r: -0.125), time spent below <90% saturation (r: -0.172), and sleep efficiency (r: 0.087) on PSG performed before PAP treatment, as well as a negative correlation between the IRLS score and weekly PAP use hours at the 12th month after PAP treatment (r: -0.316; p<0.001). The data obtained from this study suggest that the coexistence of OSAS and RLS is common and should not be overlooked in the diagnosis of comorbid diseases. Long-term PAP treatment is effective in reducing RLS symptoms. Further studies are needed on this subject.","PeriodicalId":409662,"journal":{"name":"OSMANGAZİ JOURNAL OF MEDICINE","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127868685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hereditary angioedema (HAE) is a rare autosomal dominant disease that is derived from the deficiency or dysfunction of C1 esterase inhibitor (C1-INH). In studies about the diseases that can accompany hereditary angioedema, allergic diseases occur more frequently compared to the healthy population but no studies on this issue have been carried out. This study was conducted in order to determine the frequency of the comorbidity of atopic sensitivity and allergic diseases in patients with hereditary angioedema. 32 patients who were diagnosed with hereditary angioedema in the Paediatric Allergy Polyclinic of Mersin City Hospital between 2019 and 2021 were included in the study. In these patients, the information about the existence of atopic diseases was obtained from their files and recorded. While asthma was observed in 6 (18.8%), allergic rhinitis in 18 (46.9%), and urticaria in 2 (6.2%) patients, dermatitis was not observed in any of the patients. While Fx5 test was positive in 5 (15.6%) patients, inhalant allergen mix sps IgE was positive in 7 (25.9%) patients. The IgE value was above 100 in 12 (52.2%) patients, and the eosinophil level was above 4% in 16 (50%) patients. In conclusion, we speculate in this study that the association of atopic disease and atopic sensitivity is observed more frequently in patients with angioedema than in the healthy population. However, a study with a larger sample is necessary to confirm this finding.
{"title":"Analysis of the Association of Allergic Disease in Pediatric Patients with Hereditary Angioedema","authors":"A. Aydoğdu, A. Aydoğdu","doi":"10.20515/otd.1186392","DOIUrl":"https://doi.org/10.20515/otd.1186392","url":null,"abstract":"Hereditary angioedema (HAE) is a rare autosomal dominant disease that is derived from the deficiency or dysfunction of C1 esterase inhibitor (C1-INH). In studies about the diseases that can accompany hereditary angioedema, allergic diseases occur more frequently compared to the healthy population but no studies on this issue have been carried out. This study was conducted in order to determine the frequency of the comorbidity of atopic sensitivity and allergic diseases in patients with hereditary angioedema. 32 patients who were diagnosed with hereditary angioedema in the Paediatric Allergy Polyclinic of Mersin City Hospital between 2019 and 2021 were included in the study. In these patients, the information about the existence of atopic diseases was obtained from their files and recorded. While asthma was observed in 6 (18.8%), allergic rhinitis in 18 (46.9%), and urticaria in 2 (6.2%) patients, dermatitis was not observed in any of the patients. While Fx5 test was positive in 5 (15.6%) patients, inhalant allergen mix sps IgE was positive in 7 (25.9%) patients. The IgE value was above 100 in 12 (52.2%) patients, and the eosinophil level was above 4% in 16 (50%) patients. In conclusion, we speculate in this study that the association of atopic disease and atopic sensitivity is observed more frequently in patients with angioedema than in the healthy population. However, a study with a larger sample is necessary to confirm this finding. ","PeriodicalId":409662,"journal":{"name":"OSMANGAZİ JOURNAL OF MEDICINE","volume":"62 35","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134499699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Attitudinal barriers can be more frequent than structural barriers in depression treatment. Understanding attitudinal barriers are the first step to overcome. We aimed to investigate the relationship between the beliefs about depression, antidepressants with attachment styles, and personality characteristics. A total of 207 participants completed an online survey which consisted of the sociodemographic data form, beliefs about antidepressants and depression questionnaire, Experiences in Close Relationships-Revised, and Ten Item Personality Inventory. False beliefs about depression were related to younger age, lower education level, and male gender (p<0.05 each). False beliefs about antidepressants were related to openness to experience personality dimension and anxious attachment style in addition to the male gender and, lower educational level (p<0.05 each). Interventions addressing wrong beliefs about depression should provide basic information about the disease. Clinicians aiming to provide proper knowledge about antidepressants should prioritize a trusting relationship.
{"title":"Beliefs About Depression and Antidepressants: Is There A Relationship with Attachment Style or Personality Characteristics?","authors":"İmran Gökçen Yılmaz Karaman, Melike Ezerbolat Özateş","doi":"10.20515/otd.1236903","DOIUrl":"https://doi.org/10.20515/otd.1236903","url":null,"abstract":"Attitudinal barriers can be more frequent than structural barriers in depression treatment. Understanding attitudinal barriers are the first step to overcome. We aimed to investigate the relationship between the beliefs about depression, antidepressants with attachment styles, and personality characteristics. A total of 207 participants completed an online survey which consisted of the sociodemographic data form, beliefs about antidepressants and depression questionnaire, Experiences in Close Relationships-Revised, and Ten Item Personality Inventory. False beliefs about depression were related to younger age, lower education level, and male gender (p<0.05 each). False beliefs about antidepressants were related to openness to experience personality dimension and anxious attachment style in addition to the male gender and, lower educational level (p<0.05 each). Interventions addressing wrong beliefs about depression should provide basic information about the disease. Clinicians aiming to provide proper knowledge about antidepressants should prioritize a trusting relationship.","PeriodicalId":409662,"journal":{"name":"OSMANGAZİ JOURNAL OF MEDICINE","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122256273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Yaman, Cihan Aksoy, M. Akdeniz Leblebicier, Emre Sahin
This study aimed to investigate the relationship between pain severity and depression level and quality of life in elderly patients with chronic non-specific low back pain (CNLBP) and determine the effect of age group on the quality of life, pain severity and depression symptom levels of patients. Evaluation parameters were obtained using scales specific to geriatric patients. Pain severity, depression, and quality of life were evaluated using the Geriatric Pain Measure (GPM), Geriatric Depression Scale (GDS), and World Health Organization Quality of Life Questionnaire-Older Adults Module (WHOQOL-OLD), respectively. The study included a total of 231 patients with CNLBP (age ≥65 years), of whom 62.3% (n=144) were female and 37.7% were male (n=87). There was a moderate correlation between the patients’ GDS and GPM scores (r=0.53; p<0.05). GDS also had a moderate correlation with the ‘past-present-and-future activities’ (r=-0.52) and ‘social participation’ (r=-0.48) subdomains of WHOQOL-OLD (p<0.05). According to age groups, the only statistically significant difference was observed in ‘sensory abilities’ (p<0.05). Quality of life is negatively affected by the level of depression and pain intensity in elderly individuals with CNLBP. Evaluation of pain severity and depressive symptom levels in elderly patients with CNLBP may contribute to the establishment of an elderly population with improved quality of life and treatment approach. There is a need for further studies to reveal the reasons for poorer quality of life and increased depression and pain.
{"title":"Pain and Depression Levels Related to the Quality of Life in Elderly People with Chronic Non-Specific Low Back Pain?","authors":"F. Yaman, Cihan Aksoy, M. Akdeniz Leblebicier, Emre Sahin","doi":"10.20515/otd.1231484","DOIUrl":"https://doi.org/10.20515/otd.1231484","url":null,"abstract":"This study aimed to investigate the relationship between pain severity and depression level and quality of life in elderly patients with chronic non-specific low back pain (CNLBP) and determine the effect of age group on the quality of life, pain severity and depression symptom levels of patients. Evaluation parameters were obtained using scales specific to geriatric patients. Pain severity, depression, and quality of life were evaluated using the Geriatric Pain Measure (GPM), Geriatric Depression Scale (GDS), and World Health Organization Quality of Life Questionnaire-Older Adults Module (WHOQOL-OLD), respectively. The study included a total of 231 patients with CNLBP (age ≥65 years), of whom 62.3% (n=144) were female and 37.7% were male (n=87). There was a moderate correlation between the patients’ GDS and GPM scores (r=0.53; p<0.05). GDS also had a moderate correlation with the ‘past-present-and-future activities’ (r=-0.52) and ‘social participation’ (r=-0.48) subdomains of WHOQOL-OLD (p<0.05). According to age groups, the only statistically significant difference was observed in ‘sensory abilities’ (p<0.05). Quality of life is negatively affected by the level of depression and pain intensity in elderly individuals with CNLBP. Evaluation of pain severity and depressive symptom levels in elderly patients with CNLBP may contribute to the establishment of an elderly population with improved quality of life and treatment approach. There is a need for further studies to reveal the reasons for poorer quality of life and increased depression and pain.","PeriodicalId":409662,"journal":{"name":"OSMANGAZİ JOURNAL OF MEDICINE","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130531540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Canaz, Damla Oflas, E. Yılmaz, D. Arık, Y. Aydemir, Z. Barış, Hülya Özen
Gastric (foveolar) metaplasia (GM) in the duodenum occurs in many cases where duodenitis develops histologically. However, few studies have investigated the presence of GM in celiac patients. This study aimed to determine the prevalence of GM and its relationship with clinicopathological parameters in untreated pediatric celiac patients. Duodenal biopsy specimens of 153 pediatric cases were analyzed. MUC5AC immunohistochemical staining was applied to all cases to detect GM. The patient group was evaluated in terms of the disease activity score (DAS), neutrophilic activity score (NAS), eosinophilic infiltration, and presence of intramucosal Brunner glands. The rate of GM was 53.4% in the control group and 98.8% in the patient group. GM was observed as diffuse morphology at a rate of 4.1% (n:3) in the control group and 55% (n:44) in the patient group (p<0.001). Diffuse type of GM was more frequent in girls in the patient group (p=0.03). When GM (focal/diffuse) age, DAS, NAS, and all histopathological parameters were compared, a statistically significant difference was found between diffuse GM and DAS, and NAS. (p=0.023 and p=0.039, respectively). The present study considered that duodenal neutrophilia and increased disease activity might play a role in the development of GM in celiac patients. We think that it would be appropriate to include a diffuse type of GM, which can be easily detected by immunohistochemical or histochemical methods, in pathology reports as a finding of histologically active celiac disease.
{"title":"Investigation of the frequency and significance of gastric metaplasia in duodenal biopsy materials of untreated pediatric celiac patients","authors":"F. Canaz, Damla Oflas, E. Yılmaz, D. Arık, Y. Aydemir, Z. Barış, Hülya Özen","doi":"10.20515/otd.1161843","DOIUrl":"https://doi.org/10.20515/otd.1161843","url":null,"abstract":"Gastric (foveolar) metaplasia (GM) in the duodenum occurs in many cases where duodenitis develops histologically. However, few studies have investigated the presence of GM in celiac patients. This study aimed to determine the prevalence of GM and its relationship with clinicopathological parameters in untreated pediatric celiac patients. Duodenal biopsy specimens of 153 pediatric cases were analyzed. MUC5AC immunohistochemical staining was applied to all cases to detect GM. The patient group was evaluated in terms of the disease activity score (DAS), neutrophilic activity score (NAS), eosinophilic infiltration, and presence of intramucosal Brunner glands. The rate of GM was 53.4% in the control group and 98.8% in the patient group. GM was observed as diffuse morphology at a rate of 4.1% (n:3) in the control group and 55% (n:44) in the patient group (p<0.001). Diffuse type of GM was more frequent in girls in the patient group (p=0.03). When GM (focal/diffuse) age, DAS, NAS, and all histopathological parameters were compared, a statistically significant difference was found between diffuse GM and DAS, and NAS. (p=0.023 and p=0.039, respectively). The present study considered that duodenal neutrophilia and increased disease activity might play a role in the development of GM in celiac patients. We think that it would be appropriate to include a diffuse type of GM, which can be easily detected by immunohistochemical or histochemical methods, in pathology reports as a finding of histologically active celiac disease.","PeriodicalId":409662,"journal":{"name":"OSMANGAZİ JOURNAL OF MEDICINE","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116610913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Premature ovarian failure (POF) is a clinical syndrome known to affect approximately 1% of women of reproductive age. A number of genetic, autoimmune, metabolic, infectious and environmental causes have been identified in the etiology of POF. Cadmium is a toxic metal which can accumulate in ovaries and causes a significant decrease in the binding of gonadotropins that regulate steroidogenic enzyme activity in granulosa cells. We aimed to investigate the role of cadmium in the etiology of POF. Thirty-five patients with POF were enrolled in group 1 which was the study group. Two control groups were formed from healthy participants. Thirty-fiveparticipants who were age-matched young women with regular menstruation were included in group 2.Thirty-fivehealthy postmenopausal women were included in group 3. Patients' demographic data were recorded. Serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), thyroid-stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4) and cadmium levels were measured. There was a statistically significant difference between the groups for gravida, parity and living children (p<0.001), but no difference was found for abortion (p=0.430). While there was a statistically significant difference between the groups for serum FSH, LH and E2 levels (p<0.001), no statistically significant difference was found for T3, T4 and TSH. Serum cadmium levels were found to be statistically significantly decreased in group 1 compared to g roups 2 and 3 (p<0.001). This study revealed that cadmium had no direct effect on the development of POF, but it should be kept in mind that the synergistic and antagonistic effects of metals may affect this result.
{"title":"The Role of Serum Cadmium Levels in the Etiology of Premature Ovarian Failure: A Case-Control Study","authors":"Sevil Cicek, P. Kırıcı, A. Karaer","doi":"10.20515/otd.1190726","DOIUrl":"https://doi.org/10.20515/otd.1190726","url":null,"abstract":"Premature ovarian failure (POF) is a clinical syndrome known to affect approximately 1% of women of reproductive age. A number of genetic, autoimmune, metabolic, infectious and environmental causes have been identified in the etiology of POF. Cadmium is a toxic metal which can accumulate in ovaries and causes a significant decrease in the binding of gonadotropins that regulate steroidogenic enzyme activity in granulosa cells. We aimed to investigate the role of cadmium in the etiology of POF. Thirty-five patients with POF were enrolled in group 1 which was the study group. Two control groups were formed from healthy participants. Thirty-fiveparticipants who were age-matched young women with regular menstruation were included in group 2.Thirty-fivehealthy postmenopausal women were included in group 3. Patients' demographic data were recorded. Serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), thyroid-stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4) and cadmium levels were measured. There was a statistically significant difference between the groups for gravida, parity and living children (p<0.001), but no difference was found for abortion (p=0.430). While there was a statistically significant difference between the groups for serum FSH, LH and E2 levels (p<0.001), no statistically significant difference was found for T3, T4 and TSH. Serum cadmium levels were found to be statistically significantly decreased in group 1 compared to g roups 2 and 3 (p<0.001). This study revealed that cadmium had no direct effect on the development of POF, but it should be kept in mind that the synergistic and antagonistic effects of metals may affect this result.","PeriodicalId":409662,"journal":{"name":"OSMANGAZİ JOURNAL OF MEDICINE","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131998838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nosocomial bloodstream infections are common in intensive care units, and a significant portion results in mortality. Procalcitonin is a biomarker used in the early diagnosis of bloodstream infections. Since different pathways release it, its level in the blood may differ in bloodstream infections caused by different agents. The present study was designed to demonstrate whether procalcitonin was an accurate marker in nosocomial bloodstream infections caused by Acinetobacter spp. The present study evaluated 214 bacteremia episodes of 145 patients diagnosed with nosocomial bloodstream infection. Nosocomial bloodstream infection agents were divided into four groups gram-positive bacteria, gram-negative bacteria, Acinetobacter spp., and Candida spp. At the time of diagnosis, procalcitonin, C-reactive protein, neutrophil/lymphocyte ratio, and leukocyte values were measured on the 3rd and 7th days. The mean procalcitonin value measured at the time of diagnosis was 11.7±21.8 ng/ml, the highest in the gram-negative bacteria group. The mean procalcitonin value in the gram-positive bacteria group was 2.8±6.44 ng/ml, 2.5±3.35 ng/ml in the Candida spp. group, and 3.5±12.1 ng/ml in the Acinetobacter spp. group. A significant difference was determined between the four groups regarding procalcitonin values. It was determined that the blood procalcitonin level at the time of diagnosis did not increase as expected in Acinetobacter spp.-induced nosocomial bloodstream infections. In this respect, caution should be exercised in the early diagnosis of nosocomial bloodstream infections.
{"title":"IS PROCALCITONIN AN ACCURATE MARKER IN THE DIAGNOSIS OF ACINETOBACTER-INDUCED BACTEREMIA?","authors":"Ayşegül Şeremet Keskin, Elif SARIÖNDER GENCER, Gülsüm İNCE TOPRAK, Kübra DEMİR ÖNDER","doi":"10.20515/otd.1201806","DOIUrl":"https://doi.org/10.20515/otd.1201806","url":null,"abstract":"Nosocomial bloodstream infections are common in intensive care units, and a significant portion results in mortality. Procalcitonin is a biomarker used in the early diagnosis of bloodstream infections. Since different pathways release it, its level in the blood may differ in bloodstream infections caused by different agents. The present study was designed to demonstrate whether procalcitonin was an accurate marker in nosocomial bloodstream infections caused by Acinetobacter spp. The present study evaluated 214 bacteremia episodes of 145 patients diagnosed with nosocomial bloodstream infection. Nosocomial bloodstream infection agents were divided into four groups gram-positive bacteria, gram-negative bacteria, Acinetobacter spp., and Candida spp. At the time of diagnosis, procalcitonin, C-reactive protein, neutrophil/lymphocyte ratio, and leukocyte values were measured on the 3rd and 7th days. The mean procalcitonin value measured at the time of diagnosis was 11.7±21.8 ng/ml, the highest in the gram-negative bacteria group. The mean procalcitonin value in the gram-positive bacteria group was 2.8±6.44 ng/ml, 2.5±3.35 ng/ml in the Candida spp. group, and 3.5±12.1 ng/ml in the Acinetobacter spp. group. A significant difference was determined between the four groups regarding procalcitonin values. It was determined that the blood procalcitonin level at the time of diagnosis did not increase as expected in Acinetobacter spp.-induced nosocomial bloodstream infections. In this respect, caution should be exercised in the early diagnosis of nosocomial bloodstream infections.","PeriodicalId":409662,"journal":{"name":"OSMANGAZİ JOURNAL OF MEDICINE","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116975875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hamit Celme, Tugrul Kiliboz, B. Dogan, Tuğçen Demi̇rcan, Arif Garbi̇oğlu, Ü. Şi̇mşek, K. Karbeyaz
In the forensic report, whether the injury includes "vascular injury" or not, the life-threatening situation is important for the investigation. In this study, it was aimed to evaluate the vascular injury status and share the data with the literature in cases related to forensic traumatology, which were reflected in the Forensic Medicine Department of Eskişehir Osmangazi University Faculty of Medicine. In the 5-year period between 2015 and 2019, the cases with vascular injury, who applied to the Eskişehir Osmangazi University Faculty of Medicine, Department of Forensic Medicine, were retrospectively analyzed. Report contents and demographic data of the cases were evaluated. It was determined that 52 (1.2%) of 4378 forensic cases evaluated within the scope of the study had vascular injury. 90.3% of the patients with vascular injury were male, they were most frequently in the 19-29 age group, 69.3% of the cases were stab wounds, and the most commonly injured vessel was a.femoralis and its branches (n=11, %21.2). The data obtained in the study were found to be compatible with the literature. It was thought that in-service trainings on this subject were important, especially for emergency room doctors to be more attentive in issuing forensic reports, to take necessary measures to prevent them from being held responsible in cases of vascular injury and other forensic cases, to protect the legal rights of victims.
{"title":"Evaluation of Non-fatal Forensic Vascular Injuries","authors":"Hamit Celme, Tugrul Kiliboz, B. Dogan, Tuğçen Demi̇rcan, Arif Garbi̇oğlu, Ü. Şi̇mşek, K. Karbeyaz","doi":"10.20515/otd.1210902","DOIUrl":"https://doi.org/10.20515/otd.1210902","url":null,"abstract":"In the forensic report, whether the injury includes \"vascular injury\" or not, the life-threatening situation is important for the investigation. In this study, it was aimed to evaluate the vascular injury status and share the data with the literature in cases related to forensic traumatology, which were reflected in the Forensic Medicine Department of Eskişehir Osmangazi University Faculty of Medicine. In the 5-year period between 2015 and 2019, the cases with vascular injury, who applied to the Eskişehir Osmangazi University Faculty of Medicine, Department of Forensic Medicine, were retrospectively analyzed. Report contents and demographic data of the cases were evaluated. It was determined that 52 (1.2%) of 4378 forensic cases evaluated within the scope of the study had vascular injury. 90.3% of the patients with vascular injury were male, they were most frequently in the 19-29 age group, 69.3% of the cases were stab wounds, and the most commonly injured vessel was a.femoralis and its branches (n=11, %21.2). The data obtained in the study were found to be compatible with the literature. It was thought that in-service trainings on this subject were important, especially for emergency room doctors to be more attentive in issuing forensic reports, to take necessary measures to prevent them from being held responsible in cases of vascular injury and other forensic cases, to protect the legal rights of victims.","PeriodicalId":409662,"journal":{"name":"OSMANGAZİ JOURNAL OF MEDICINE","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123597539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Spiral groove entrapment neuropathy is a compression neuropathy that can occur for various reasons due to the superficial course of the radial nerve at the level of the spiral groove. Since repetitive movements play a role in the development mechanism of compression neuropathy, compelling and repetitive movements of the triceps muscle may predispose to spiral groove entrapment neuropathy. In this case, a 61-year-old male patient who developed a low hand after long-term use of a lawnmower is presented. The patient was diagnosed with spiral groove entrapment neuropathy as a result of the physical examination findings performed in our clinic and the requested electroneurophysiological test, magnetic resonance imaging. The patient's motor and sensory deficit completely recovered after 6 weeks as a result of physical therapy and acupuncture treatment.
{"title":"Spiral Groove Entrapment Neuropathy Due to Overuse of The Triceps: A Case Report","authors":"O. Armağan, Burcu Ortanca","doi":"10.20515/otd.1225213","DOIUrl":"https://doi.org/10.20515/otd.1225213","url":null,"abstract":"Spiral groove entrapment neuropathy is a compression neuropathy that can occur for various reasons due to the superficial course of the radial nerve at the level of the spiral groove. Since repetitive movements play a role in the development mechanism of compression neuropathy, compelling and repetitive movements of the triceps muscle may predispose to spiral groove entrapment neuropathy. In this case, a 61-year-old male patient who developed a low hand after long-term use of a lawnmower is presented. The patient was diagnosed with spiral groove entrapment neuropathy as a result of the physical examination findings performed in our clinic and the requested electroneurophysiological test, magnetic resonance imaging. The patient's motor and sensory deficit completely recovered after 6 weeks as a result of physical therapy and acupuncture treatment.","PeriodicalId":409662,"journal":{"name":"OSMANGAZİ JOURNAL OF MEDICINE","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132202191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Kocatürk, E. Gunduz, H. Kayadibi, H. Üsküdar Teke, İ. Ö. Alatas
The time of initiating stem cell collection is very important for successful transplantation and is determined according to peripheral blood CD34+ cell count analysed by flow cytometry. In this study, we aimed to find the role of new complete blood count parameters to determine the optimal time of stem cell collection. Eighty-six patients who underwent stem cell mobilization were included in the study. Peripheral blood CD34+ cells and complete blood count were analysed on the same day. Patients with peripheral blood CD 34+ cell counts ≤ 20/μL and > 20/μL were determined as Group 1 and Group 2, respectively. The difference of CBC parameters between 2 groups and the relationship of these parameters with peripheral blood CD34+ cell counts were evaluated. It was found that immature granulocytes ratio, nucleated red blood cells ratio and count were positively correlated with peripheral blood CD34+ cell count and these parameters were significantly different between two groups (P< 0.001, P= 0.011 and P= 0.012, respectively). The new index formulated by using immature granulocytes and nucleated red blood cells ratios was significantly different between two groups (P<0.001), and had the highest diagnostic accuracy to determine the time of stem cell collection (AUC= 0.766). Immature granulocytes and nucleated red blood cells can be used to determine the time of peripheral blood stem cell collection faster and cheaper compared to flow cytometry.
{"title":"The Optimal Time of Peripheral Blood Hematopoietic Stem Cell Collection for Autologous Transplantation May Be Predicted By Immature Granulocytes and Nucleated Red Blood Cells","authors":"E. Kocatürk, E. Gunduz, H. Kayadibi, H. Üsküdar Teke, İ. Ö. Alatas","doi":"10.20515/otd.1210794","DOIUrl":"https://doi.org/10.20515/otd.1210794","url":null,"abstract":"The time of initiating stem cell collection is very important for successful transplantation and is determined according to peripheral blood CD34+ cell count analysed by flow cytometry. In this study, we aimed to find the role of new complete blood count parameters to determine the optimal time of stem cell collection. Eighty-six patients who underwent stem cell mobilization were included in the study. Peripheral blood CD34+ cells and complete blood count were analysed on the same day. Patients with peripheral blood CD 34+ cell counts ≤ 20/μL and > 20/μL were determined as Group 1 and Group 2, respectively. The difference of CBC parameters between 2 groups and the relationship of these parameters with peripheral blood CD34+ cell counts were evaluated. It was found that immature granulocytes ratio, nucleated red blood cells ratio and count were positively correlated with peripheral blood CD34+ cell count and these parameters were significantly different between two groups (P< 0.001, P= 0.011 and P= 0.012, respectively). The new index formulated by using immature granulocytes and nucleated red blood cells ratios was significantly different between two groups (P<0.001), and had the highest diagnostic accuracy to determine the time of stem cell collection (AUC= 0.766). Immature granulocytes and nucleated red blood cells can be used to determine the time of peripheral blood stem cell collection faster and cheaper compared to flow cytometry.","PeriodicalId":409662,"journal":{"name":"OSMANGAZİ JOURNAL OF MEDICINE","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128986033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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