Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.08
Fahad Aljarboa, Saleh Almanea, Abdullah Aljarboa, Tala Almanea, Bader Aldebasi
Objective was assess the knowledge of the adult women with regards to the benefits of breastfeeding at Prince Bader Housing. This study was a cross-sectional survey targeting mothers visiting primary health care clinics. Nearly 200 single-page questionnaires with 20 questions were distributed to visiting mothers at the well-baby clinics. Sampling was convenient and randomness was assumed by visit sequence, on a "first-come-first-serve" basis, and those who agreed to participate. Mothers visiting the O.B clinic or visiting the Pediatrician and Well-Baby Clinic within the PHC centers for immunization of their children (under 2 years of age) SPSS was used for data analysis. The total subjects in this study were 188, the average age of the participants was 32.6 years with a standard deviation of 32, the youngest age of the participant was 22 years and oldest age was 46 years and the average family size was 1.5 (roughly 2 children). A substantial majority of mothers agreed that breast milk is better than any formula milk. More than three-fourths of the mothers responded that Exclusive breastfeeding should be given. The majority of mothers can identify the colostrum in breast milk, majority of mothers believed that breastfeeding will protect their baby from specific diseases.In this study, more than two-thirds of the mothers answered questions in a manner that indicates they are well educated about the benefit of breastfeeding. This points towards the implementation of a good educational program for mothers by healthcare providers.
{"title":"Assessment on Knowledge of Adult Women with Regards to Benefits of Breastfeeding at Prince Bader Housing","authors":"Fahad Aljarboa, Saleh Almanea, Abdullah Aljarboa, Tala Almanea, Bader Aldebasi","doi":"10.5455/jcmr.2023.14.01.08","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.08","url":null,"abstract":"Objective was assess the knowledge of the adult women with regards to the benefits of breastfeeding at Prince Bader Housing. This study was a cross-sectional survey targeting mothers visiting primary health care clinics. Nearly 200 single-page questionnaires with 20 questions were distributed to visiting mothers at the well-baby clinics. Sampling was convenient and randomness was assumed by visit sequence, on a \"first-come-first-serve\" basis, and those who agreed to participate. Mothers visiting the O.B clinic or visiting the Pediatrician and Well-Baby Clinic within the PHC centers for immunization of their children (under 2 years of age) SPSS was used for data analysis. The total subjects in this study were 188, the average age of the participants was 32.6 years with a standard deviation of 32, the youngest age of the participant was 22 years and oldest age was 46 years and the average family size was 1.5 (roughly 2 children). A substantial majority of mothers agreed that breast milk is better than any formula milk. More than three-fourths of the mothers responded that Exclusive breastfeeding should be given. The majority of mothers can identify the colostrum in breast milk, majority of mothers believed that breastfeeding will protect their baby from specific diseases.In this study, more than two-thirds of the mothers answered questions in a manner that indicates they are well educated about the benefit of breastfeeding. This points towards the implementation of a good educational program for mothers by healthcare providers.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"33 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76231669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.11
Andronik Karapetov, I. Lysenko, Aglaya Kazumova, Ilmira Zakirova, K. Kuzmina, Anastasia Islivanova
This article examines the role of physical activity and sports in the prevention and treatment of chronic diseases based on modern scientific data and practical recommendations. The paper describes the mechanisms of the impact of physical activity on the body, including the improvement of metabolism and functions of the cardiovascular system, as well as the prevention and treatment of diseases such as obesity, diabetes, hypertension, heart and vascular diseases, depression and others.The study provides an overview of the results of many studies demonstrating that physical activity and sport have significant therapeutic potential for patients with chronic diseases. The article also provides practical recommendations on the choice of optimal types of physical activity and sports, the frequency and duration of classes, depending on the state of health, age and other factors.It is also noted that physical exercises should be individualized and aimed at achieving specific goals for each patient. At the same time, it is important to take into account the peculiarities of health and age, as well as to observe safety measures and monitor loads.One of the main conclusions of the article is the fact that physical activity and sport not only prevent the development of many chronic diseases, but also can improve the quality of life of patients, as well as reduce the risk of mortality from cardiovascular diseases.Thus, the study highlights the importance of regular physical exercise for the prevention and treatment of chronic diseases, and also recommends that doctors integrate this approach into their practice.
{"title":"The Role Of Physical Activity And Sports In The Prevention And Treatment Of Chronic Diseases: Modern Scientific Data And Practical\u0000Recommendations","authors":"Andronik Karapetov, I. Lysenko, Aglaya Kazumova, Ilmira Zakirova, K. Kuzmina, Anastasia Islivanova","doi":"10.5455/jcmr.2023.14.03.11","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.11","url":null,"abstract":"This article examines the role of physical activity and sports in the prevention and treatment of chronic diseases based on modern scientific data and practical recommendations. The paper describes the mechanisms of the impact of physical activity on the body, including the improvement of metabolism and functions of the cardiovascular system, as well as the prevention and treatment of diseases such as obesity, diabetes, hypertension, heart and vascular diseases, depression and others.The study provides an overview of the results of many studies demonstrating that physical activity and sport have significant therapeutic potential for patients with chronic diseases. The article also provides practical recommendations on the choice of optimal types of physical activity and sports, the frequency and duration of classes, depending on the state of health, age and other factors.It is also noted that physical exercises should be individualized and aimed at achieving specific goals for each patient. At the same time, it is important to take into account the peculiarities of health and age, as well as to observe safety measures and monitor loads.One of the main conclusions of the article is the fact that physical activity and sport not only prevent the development of many chronic diseases, but also can improve the quality of life of patients, as well as reduce the risk of mortality from cardiovascular diseases.Thus, the study highlights the importance of regular physical exercise for the prevention and treatment of chronic diseases, and also recommends that doctors integrate this approach into their practice.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"31 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91198028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.23
Bhavana Garapati, S. Varghese, V. J, Karthikeyan Murthykumar
Background: Cytokine IL18, also known as IFN-inducing factor, is an important regulator of innate and acquired immune responses and plays a number of roles in chronic inflammation and dysfunction autoimmune disorder. Several polymorphisms in the IL18 promoter region have been identified. As there is little evidence for IL18 polymorphisms and periodontitis, this study aimed to evaluate the genetic association of polymorphisms of the IL18 gene (rs1946518). Materials and Methods: A total of 100 subjects were recruited for this study, including 50 patients with periodontitis (stage II, III and grade B) and 50 patients with healthy gingiva clinically intact periodontium. Genomic DNA was extracted from the blood obtained from the subjects. DNA was amplified using primers specific to the MseI region of the IL18 receptor gene. Amplicon was further genotyped using the restriction fragment length using the BtgI enzyme. Genotyping obtained on the basis of the RFLP model was recorded and used for statistical analysis. The distributions of genotypes and allele frequencies in the periodontal disease group and the control group were compared using the Chi Square test. Risks associated with individual alleles or genotypes were calculated using odds ratios (ORs) with 95% confidence intervals. Statistical significance in all trials was determined at p <0.05. Result: The frequencies of genotypes and the distribution of IL18 receptor MseI polymorphisms were not significantly different at ꭕ2df (P = .818). The results of our study showed that there was no significant difference between homozygous and heterozygous genotypes (GG vs TG TT) between periodontitis patients and control group with a P value of 0.8316. The detection frequencies of the TG (20% vs 22%) and TT (14% vs 10%) genotypes showed a significant difference (P value = 0.8316) between the control and experimental groups. experience. There were no significant differences for the G allele (76% vs 79%) and the T allele (24% vs 21%) between the experimental and control groups. Conclusions: The present study indicated that the polymorphism of the IL18 gene was not associated with CP in the analyzed study group.
背景:细胞因子IL18，又称ifn诱导因子，是先天和获得性免疫反应的重要调节因子，在慢性炎症和自身免疫性疾病中发挥多种作用。已经确定了IL18启动子区域的几个多态性。由于IL18基因多态性与牙周炎之间的关联证据较少，本研究旨在评估IL18基因(rs1946518)多态性与牙周炎之间的遗传关联。材料与方法:本研究共招募100名受试者，包括50名牙周炎患者(II期、III期和B级)和50名健康牙龈临床完整牙周组织的患者。从受试者的血液中提取基因组DNA。利用il - 18受体基因MseI区特异性引物扩增DNA。利用BtgI酶进一步利用限制性片段长度对扩增子进行基因分型。记录基于RFLP模型得到的基因分型并进行统计分析。采用卡方检验比较牙周病组与对照组基因型及等位基因频率的分布。使用比值比(ORs)计算与单个等位基因或基因型相关的风险，置信区间为95%。所有试验均以p <0.05为差异有统计学意义。结果:在ꭕ2df上，基因型频率和IL18受体MseI多态性分布无显著性差异(P = .818)。本研究结果显示，牙周炎患者与对照组纯合子与杂合子基因型(GG vs TG TT)差异无统计学意义，P值为0.8316。TG (20% vs 22%)和TT (14% vs 10%)基因型检出率在对照组和试验组之间差异有统计学意义(P值= 0.8316)。体验。G等位基因(76% vs 79%)和T等位基因(24% vs 21%)在实验组和对照组之间无显著差异。结论:本研究表明，在分析的研究组中，il - 18基因多态性与CP无关。
{"title":"Association Of Il18 Gene Polymorphism with Susceptibility to Periodontitis - A Case Control Study","authors":"Bhavana Garapati, S. Varghese, V. J, Karthikeyan Murthykumar","doi":"10.5455/jcmr.2023.14.03.23","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.23","url":null,"abstract":"Background: Cytokine IL18, also known as IFN-inducing factor, is an important regulator of innate and acquired immune responses and plays a number of roles in chronic inflammation and dysfunction autoimmune disorder. Several polymorphisms in the IL18 promoter region have been identified. As there is little evidence for IL18 polymorphisms and periodontitis, this study aimed to evaluate the genetic association of polymorphisms of the IL18 gene (rs1946518). Materials and Methods: A total of 100 subjects were recruited for this study, including 50 patients with periodontitis (stage II, III and grade B) and 50 patients with healthy gingiva clinically intact periodontium. Genomic DNA was extracted from the blood obtained from the subjects. DNA was amplified using primers specific to the MseI region of the IL18 receptor gene. Amplicon was further genotyped using the restriction fragment length using the BtgI enzyme. Genotyping obtained on the basis of the RFLP model was recorded and used for statistical analysis. The distributions of genotypes and allele frequencies in the periodontal disease group and the control group were compared using the Chi Square test. Risks associated with individual alleles or genotypes were calculated using odds ratios (ORs) with 95% confidence intervals. Statistical significance in all trials was determined at p <0.05. Result: The frequencies of genotypes and the distribution of IL18 receptor MseI polymorphisms were not significantly different at ꭕ2df (P = .818). The results of our study showed that there was no significant difference between homozygous and heterozygous genotypes (GG vs TG TT) between periodontitis patients and control group with a P value of 0.8316. The detection frequencies of the TG (20% vs 22%) and TT (14% vs 10%) genotypes showed a significant difference (P value = 0.8316) between the control and experimental groups. experience. There were no significant differences for the G allele (76% vs 79%) and the T allele (24% vs 21%) between the experimental and control groups. Conclusions: The present study indicated that the polymorphism of the IL18 gene was not associated with CP in the analyzed study group.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"43 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73705643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.20
Harshitha Nagothu, Koushik Yetukuri, R. Nadendla
A system of pharmacovigilance is a field of pharmacological sciences that deals with the Adverse Events Reaction reporting produced by medical devices and or drugs. One of the possible public health problems is an adverse event, which needs ongoing recording, assessment, and surveillance. Drug regulations have improved and got stronger since the 1937 sulphanilamide tragedy and the1960 thalidomide disaster. As such response, a Pharmacovigilance System was developed, which is capable of receiving, diagnosing, evaluating, monitoring, and mitigating harmful effects of medical products. The Central Drug Standard Control Organization-CDSCO regulates India's pharmacovigilance system, whereas the United States Food and Drug Administration-USFDA regulates the US pharmacovigilance system. In India, the pharmacovigilance programme monitors adverse drug responses. India has a Pharmacovigilance Program in place to track adverse drug reactions. The United States likewise has strict laws in place to strengthen Food & Drug Administration (FDA) pharmacovigilance requirements. (WHO) -World Health Organization established an International Monitoring System in collaboration with (UMC) Uppsala Monitoring Centre.
{"title":"Comparitive Study of Pharmacovigilance System in India and USA","authors":"Harshitha Nagothu, Koushik Yetukuri, R. Nadendla","doi":"10.5455/jcmr.2023.14.02.20","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.20","url":null,"abstract":"A system of pharmacovigilance is a field of pharmacological sciences that deals with the Adverse Events Reaction reporting produced by medical devices and or drugs. One of the possible public health problems is an adverse event, which needs ongoing recording, assessment, and surveillance. Drug regulations have improved and got stronger since the 1937 sulphanilamide tragedy and the1960 thalidomide disaster. As such response, a Pharmacovigilance System was developed, which is capable of receiving, diagnosing, evaluating, monitoring, and mitigating harmful effects of medical products. The Central Drug Standard Control Organization-CDSCO regulates India's pharmacovigilance system, whereas the United States Food and Drug Administration-USFDA regulates the US pharmacovigilance system. In India, the pharmacovigilance programme monitors adverse drug responses. India has a Pharmacovigilance Program in place to track adverse drug reactions. The United States likewise has strict laws in place to strengthen Food & Drug Administration (FDA) pharmacovigilance requirements. (WHO) -World Health Organization established an International Monitoring System in collaboration with (UMC) Uppsala Monitoring Centre.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76428441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.34
Ahmed Almansour
Background & Aims: Injuries to the anterior cruciate ligament (ACL) are among the most common types of injuries that occur during sport activities. Some studies reported that the dominance leg is significant predictor for ACL injuries. However, it is unclear whether the dominant or non-dominant leg impacts functional status and psychological readiness to return to sport after ACL. The purpose of this study was to determine if there are difference in functional performance and psychological readiness to return to sport between individuals who injured their dominant leg and non-dominant leg after 1-10 years following ACL reconstruction. Methods: A cross-sectional study of 50 participants between 20 and 38 years was conducted, to investigate individuals who injured their dominant leg (n=25) and non-dominant leg (n=25) after 1-10 years following ACL reconstruction. All participants complete Anterior Cruciate Ligament Return to Sport after Injury (ACL-RSI), the Lower Extremity Functional Scale (LEFS) questionnaires and Fear Avoidance Belief Questionnaire physical activity (FABQ-PA). Results: No significant difference was found between the dominant leg and non-dominant leg groups in ACL-RSI, LEFS and FABQ-PA (U = 256, p = 0.27; U = 314.5, p = 0.96, and U=279.5 p=0.52) respectively. Conclusions: While it is essential to investigate the functional performance and patient's psychological state, dominance vs non- dominance leg does not influence these outcomes 1-10 years following ACL reconstruction. Therefore, injuries either dominance or non-dominance leg demonstrate equal long-term improvement. To enhance rehabilitation and optimize long-term functional outcomes for individual undergoing ACL reconstruction, future research should investigate other factors that impact recovery and return-to-sport outcomes.
{"title":"Functional performance and psychological readiness after 1–10 years ACL reconstruction: A comparison between dominant and nondominant legs","authors":"Ahmed Almansour","doi":"10.5455/jcmr.2023.14.03.34","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.34","url":null,"abstract":"Background & Aims: Injuries to the anterior cruciate ligament (ACL) are among the most common types of injuries that occur during sport activities. Some studies reported that the dominance leg is significant predictor for ACL injuries. However, it is unclear whether the dominant or non-dominant leg impacts functional status and psychological readiness to return to sport after ACL. The purpose of this study was to determine if there are difference in functional performance and psychological readiness to return to sport between individuals who injured their dominant leg and non-dominant leg after 1-10 years following ACL reconstruction. Methods: A cross-sectional study of 50 participants between 20 and 38 years was conducted, to investigate individuals who injured their dominant leg (n=25) and non-dominant leg (n=25) after 1-10 years following ACL reconstruction. All participants complete Anterior Cruciate Ligament Return to Sport after Injury (ACL-RSI), the Lower Extremity Functional Scale (LEFS) questionnaires and Fear Avoidance Belief Questionnaire physical activity (FABQ-PA). Results: No significant difference was found between the dominant leg and non-dominant leg groups in ACL-RSI, LEFS and FABQ-PA (U = 256, p = 0.27; U = 314.5, p = 0.96, and U=279.5 p=0.52) respectively. Conclusions: While it is essential to investigate the functional performance and patient's psychological state, dominance vs non- dominance leg does not influence these outcomes 1-10 years following ACL reconstruction. Therefore, injuries either dominance or non-dominance leg demonstrate equal long-term improvement. To enhance rehabilitation and optimize long-term functional outcomes for individual undergoing ACL reconstruction, future research should investigate other factors that impact recovery and return-to-sport outcomes.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"348 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75945053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.27
Shaza Waggass
Objective: The objective of this study is to review the outcomes of gestational trophoblastic disease in our center, and to compare it with international figures. We will calculate the rates of remission, recurrence, and mortality. Also, we will determine the mean duration taken for normalization of β-hCG level after initiation of treatment, and the distribution of the disease by age and parity. Methods: Retrospective chart review of the patients diagnosed with gestational trophoblastic disease (GTD) and treated in King Khalid National Guard Hospital in the period between January 2000 and December 2005. Results: During the study period, there were 29 cases of gestational trophoblastic disease. The majority of the cases were non-metastatic GTD (55.2%) followed by, in decreasing order of frequency, molar pregnancy (24.1%), metastatic high-risk GTD (10.3%), metastatic low-risk GTD (6.9%) and placental-site trophoblastic tumor (3.4%). Patient's age ranged from sixteen to fifty-three years old, with the majority in the fourth decade of life (37.9%). The parity as well was highly variable from zero to fifteen, with the majority between five and ten (37.9%). Remission rate in the malignant GTD was 85.7%. There were no cases of recurrence during the follow-up period. The overall mortality rate was 3.4%. The mean duration required for normalization of β-hCG level was 10.3 weeks for molar pregnancy and 11.6 weeks for malignant GTD. Conclusion: The chemotherapy success rate, remission rate & mortality rate were similar to that reported in earlier studies. There is a need for patient education regarding strict follow-up for early detection and intervention of malignant sequelae.
{"title":"Outcomes of Gestational Trophoblastic Disease in King Khalid National Guard Hospital","authors":"Shaza Waggass","doi":"10.5455/jcmr.2023.14.03.27","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.27","url":null,"abstract":"Objective: The objective of this study is to review the outcomes of gestational trophoblastic disease in our center, and to compare it with international figures. We will calculate the rates of remission, recurrence, and mortality. Also, we will determine the mean duration taken for normalization of β-hCG level after initiation of treatment, and the distribution of the disease by age and parity. Methods: Retrospective chart review of the patients diagnosed with gestational trophoblastic disease (GTD) and treated in King Khalid National Guard Hospital in the period between January 2000 and December 2005. Results: During the study period, there were 29 cases of gestational trophoblastic disease. The majority of the cases were non-metastatic GTD (55.2%) followed by, in decreasing order of frequency, molar pregnancy (24.1%), metastatic high-risk GTD (10.3%), metastatic low-risk GTD (6.9%) and placental-site trophoblastic tumor (3.4%). Patient's age ranged from sixteen to fifty-three years old, with the majority in the fourth decade of life (37.9%). The parity as well was highly variable from zero to fifteen, with the majority between five and ten (37.9%). Remission rate in the malignant GTD was 85.7%. There were no cases of recurrence during the follow-up period. The overall mortality rate was 3.4%. The mean duration required for normalization of β-hCG level was 10.3 weeks for molar pregnancy and 11.6 weeks for malignant GTD. Conclusion: The chemotherapy success rate, remission rate & mortality rate were similar to that reported in earlier studies. There is a need for patient education regarding strict follow-up for early detection and intervention of malignant sequelae.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"72 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77282362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.27
Kaviya Selvaraj, A. Arthanari, S. Rajeshkumar
Introduction: Rose (rosa canina) is one of the flowers that are much in demand by the community because besides being an ornamental flower it can also be used as a cosmetic. Traditional medicinal herbs have seen a rebound in recent years, and as a result, pharmaceutical companies are investing heavily in developing natural medications derived from plants. Aim: To study the Anti-diabetic activity of Rose Jasmine formulation mediated silver nanoparticles. Materials and methods: The anti-diabetic activity was tested by the following inhibition of α-glucosidase at different concentrations of the prepared extract mediated with silver nanoparticles. Result: Using rosa and jasminum extract in the manufacture of silver nanoparticles, the nanoparticles showed remarkable anti-diabetic activity. It was discovered that the herbal effect was less harmful. Rosa jasminum extract of AgNps showed good anti-diabetic efficacy in the BSA assays. Conclusion: Result of this study suggest that biosynthesis of silver nano particle using rose and Jasmine showed its anti diabetic activity
{"title":"Biosynthesis Of Silver Nanoparticles Using Rose and Jasmine and Its Anti Diabetic Potential","authors":"Kaviya Selvaraj, A. Arthanari, S. Rajeshkumar","doi":"10.5455/jcmr.2023.14.01.27","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.27","url":null,"abstract":"Introduction: Rose (rosa canina) is one of the flowers that are much in demand by the community because besides being an ornamental flower it can also be used as a cosmetic. Traditional medicinal herbs have seen a rebound in recent years, and as a result, pharmaceutical companies are investing heavily in developing natural medications derived from plants. Aim: To study the Anti-diabetic activity of Rose Jasmine formulation mediated silver nanoparticles. Materials and methods: The anti-diabetic activity was tested by the following inhibition of α-glucosidase at different concentrations of the prepared extract mediated with silver nanoparticles. Result: Using rosa and jasminum extract in the manufacture of silver nanoparticles, the nanoparticles showed remarkable anti-diabetic activity. It was discovered that the herbal effect was less harmful. Rosa jasminum extract of AgNps showed good anti-diabetic efficacy in the BSA assays. Conclusion: Result of this study suggest that biosynthesis of silver nano particle using rose and Jasmine showed its anti diabetic activity","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"32 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86900652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.28
Medjid Nesturov, V. Pavalaki, Diana Ovsyannikova, A. Romanenko, Yu. S. Trusov
The article examines the possibilities of modern medicine in the field of early diagnosis of Parkinson’s disease. As the author points out, the pathogenesis of Parkinson’s disease is a complex mechanism that includes many different processes and mechanisms. Understanding these processes and mechanisms can help in the development of new methods of treatment and prevention of PD. Despite the fact that all aspects of the pathogenesis of PD have not been fully studied, there are a number of drugs and technologies that can slow down or reduce the manifestation of PD symptoms.
{"title":"Possibilities of Modern Medicine in the Field of Early Diagnosis of Parkinson’s Disease","authors":"Medjid Nesturov, V. Pavalaki, Diana Ovsyannikova, A. Romanenko, Yu. S. Trusov","doi":"10.5455/jcmr.2023.14.02.28","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.28","url":null,"abstract":"The article examines the possibilities of modern medicine in the field of early diagnosis of Parkinson’s disease. As the author points out, the pathogenesis of Parkinson’s disease is a complex mechanism that includes many different processes and mechanisms. Understanding these processes and mechanisms can help in the development of new methods of treatment and prevention of PD. Despite the fact that all aspects of the pathogenesis of PD have not been fully studied, there are a number of drugs and technologies that can slow down or reduce the manifestation of PD symptoms.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"173 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79567972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.03
S. Rajalakshmi, R. Subhasree, Rajalakshmanan Easwaramoorthy, Thiyaneswaran Nesappan
Aim: To assess the characterization, antimicrobial activity of green synthesised magnesium oxide nanoparticles using Psydium guajava leaves. Materials And Methods: Psydium guajava leaves were dried and ground, of which 2 g of the powder was used for the study.the powder was then dissolved in 100ml of distilled water. 1 mg of magnesium chloride salt was dissolved in 20 ml of distilled water. Both the solutions were mixed and subjected to centrifuge. After the preparation of the nanoparticle, it was subjected for further investigation like SEM analysis, EDAX, UV-VIs, cytotoxicity and anti microbial tests. The cytotoxicity was investigated using a brine shrimps bioassay.The number of surviving naupli cells were manually counted under dissection microscope. The antibacterial activity was examined against four bacterial strains- E.coli, E.fecalis,S.aureus,P.aurogenosa by agar well diffusion method .The inoculated plates were incubated overnight (for about 24 hours at 37 degree celsius) and the inhibition zone around the nanoparticle solution was calculated. The antimicrobial tests were carried against standard antibiotic and the results were tabulated. Results: SEM analysis showed a particle size of 70 nm and the UV -Visible spectroscopy showed a peak at 320nm confirming the presence of magnesium oxide nanoparticles that is prepared using Psydium guajava. Cytotoxicty tests revealed that 83% of the brine shrimp cells survived .The anti microbial tests revealed that the nanoparticle was effective against two micro-organisms -S.aureus and E.fecalis and their zone of inhibition was nearly equal to that of standard antibiotic against which the organisms were incubated. Conclusion: Psydium guajava synthesized magnesium nanoparticles were found to have good cytotoxicity and acceptable anti-microbial activity especially against two most commonly harbouring micro-organism(S.aureus and E.faecalis) .Hence they can be extended for use in soft tissue healing.
{"title":"Assessment of the characterization antimicrobial and green synthesis of magnesium oxide nanoparticles using Psydium guajava - in-vitro analysi","authors":"S. Rajalakshmi, R. Subhasree, Rajalakshmanan Easwaramoorthy, Thiyaneswaran Nesappan","doi":"10.5455/jcmr.2023.14.02.03","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.03","url":null,"abstract":"Aim: To assess the characterization, antimicrobial activity of green synthesised magnesium oxide nanoparticles using Psydium guajava leaves. Materials And Methods: Psydium guajava leaves were dried and ground, of which 2 g of the powder was used for the study.the powder was then dissolved in 100ml of distilled water. 1 mg of magnesium chloride salt was dissolved in 20 ml of distilled water. Both the solutions were mixed and subjected to centrifuge. After the preparation of the nanoparticle, it was subjected for further investigation like SEM analysis, EDAX, UV-VIs, cytotoxicity and anti microbial tests. The cytotoxicity was investigated using a brine shrimps bioassay.The number of surviving naupli cells were manually counted under dissection microscope. The antibacterial activity was examined against four bacterial strains- E.coli, E.fecalis,S.aureus,P.aurogenosa by agar well diffusion method .The inoculated plates were incubated overnight (for about 24 hours at 37 degree celsius) and the inhibition zone around the nanoparticle solution was calculated. The antimicrobial tests were carried against standard antibiotic and the results were tabulated. Results: SEM analysis showed a particle size of 70 nm and the UV -Visible spectroscopy showed a peak at 320nm confirming the presence of magnesium oxide nanoparticles that is prepared using Psydium guajava. Cytotoxicty tests revealed that 83% of the brine shrimp cells survived .The anti microbial tests revealed that the nanoparticle was effective against two micro-organisms -S.aureus and E.fecalis and their zone of inhibition was nearly equal to that of standard antibiotic against which the organisms were incubated. Conclusion: Psydium guajava synthesized magnesium nanoparticles were found to have good cytotoxicity and acceptable anti-microbial activity especially against two most commonly harbouring micro-organism(S.aureus and E.faecalis) .Hence they can be extended for use in soft tissue healing.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"2 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87456680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.05
M. Aksenova, Tamila Adamova, Nasur K. Ramazanov, Svetlana Skorubskaya, Elena Perepechko, D. Komarenko
This article discusses the possibility of acute kidney failure (AKF) as a result of various diagnostic and therapeutic procedures. In particular, the possibility of developing contrast nephropathy with the use of X-ray contrast agents and the possibility of developing AKF as a result of the use of nonsteroidal anti-inflammatory drugs is being studied. The authors investigate the main causes of acute kidney failure associated with diagnostic and therapeutic procedures, and give recommendations for the prevention of these complications. In particular, precautions are discussed when using contrast agents and the use of nonsteroidal anti-inflammatory drugs. The article also discusses various methods of diagnosis of acute kidney failure and methods of treatment of this condition. The authors emphasize that early detection and treatment of AKF can significantly reduce the risk of complications and improve the prognosis for patients. In addition, the article also emphasizes the importance of preventing acute kidney failure, especially in patients at increased risk of developing this condition, such as the elderly, patients with diabetic nephropathy and patients with concomitant diseases. The paper also discusses the need for further research to better understand the causes and mechanisms of the development of acute kidney failure during various diagnostic and therapeutic procedures. In general, the article provides an overview of the problem of acute kidney failure as a complication of diagnostic and therapeutic procedures, and also offers practical recommendations to reduce the risk of this complication.
{"title":"Acute Kidney Failure as A Complication of Individual Diagnostic and Therapeutic Procedures","authors":"M. Aksenova, Tamila Adamova, Nasur K. Ramazanov, Svetlana Skorubskaya, Elena Perepechko, D. Komarenko","doi":"10.5455/jcmr.2023.14.03.05","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.05","url":null,"abstract":"This article discusses the possibility of acute kidney failure (AKF) as a result of various diagnostic and therapeutic procedures. In particular, the possibility of developing contrast nephropathy with the use of X-ray contrast agents and the possibility of developing AKF as a result of the use of nonsteroidal anti-inflammatory drugs is being studied. The authors investigate the main causes of acute kidney failure associated with diagnostic and therapeutic procedures, and give recommendations for the prevention of these complications. In particular, precautions are discussed when using contrast agents and the use of nonsteroidal anti-inflammatory drugs. The article also discusses various methods of diagnosis of acute kidney failure and methods of treatment of this condition. The authors emphasize that early detection and treatment of AKF can significantly reduce the risk of complications and improve the prognosis for patients. In addition, the article also emphasizes the importance of preventing acute kidney failure, especially in patients at increased risk of developing this condition, such as the elderly, patients with diabetic nephropathy and patients with concomitant diseases. The paper also discusses the need for further research to better understand the causes and mechanisms of the development of acute kidney failure during various diagnostic and therapeutic procedures. In general, the article provides an overview of the problem of acute kidney failure as a complication of diagnostic and therapeutic procedures, and also offers practical recommendations to reduce the risk of this complication.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":"8 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82482332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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