Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.25
R. Bharath, A. Arthanari, S. Rajeshkumar
Introduction: In recent years, there has been a resurgence in the use of traditional medicinal herbs, and as a result, pharmaceutical companies are investing heavily in developing natural medications derived from plants. Nanoparticles act in a number of potential ways and fields. Chemical synthesis of nanoparticles is no longer advantageous compared to plant-based synthesis. The current study uses a green method to create silver nanoparticles (AgNPs) utilizing flower extract. Materials and methods: The anti-inflammatory activity for gel was tested by the following convention proposed by Muzushima and Kabayashi with specific alterations. 0.05 mL of Rosa and jasminum jel of various fixations. Result: Using rosa and jasminum extract in the manufacture of silver nanoparticles, the nanoparticles showed remarkable antioxidant and anti-inflammatory activity. It was discovered that the cytotoxic effect was less harmful, demonstrating biocompatibility. Rosa jasminum extract of AgNps showed good anti-inflammatory efficacy in the EA and BSA assays. Conclusion: From our study we concluded that Silver nanoparticles were created using rosa and jasminum extract, and the nanoparticles displayed impressive anti-inflammatory.
{"title":"Anti Inflammatory activity of AgNps synthesized using flower formulation (Rosa andJasminum","authors":"R. Bharath, A. Arthanari, S. Rajeshkumar","doi":"10.5455/jcmr.2023.14.01.25","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.25","url":null,"abstract":"Introduction: In recent years, there has been a resurgence in the use of traditional medicinal herbs, and as a result, pharmaceutical companies are investing heavily in developing natural medications derived from plants. Nanoparticles act in a number of potential ways and fields. Chemical synthesis of nanoparticles is no longer advantageous compared to plant-based synthesis. The current study uses a green method to create silver nanoparticles (AgNPs) utilizing flower extract. Materials and methods: The anti-inflammatory activity for gel was tested by the following convention proposed by Muzushima and Kabayashi with specific alterations. 0.05 mL of Rosa and jasminum jel of various fixations. Result: Using rosa and jasminum extract in the manufacture of silver nanoparticles, the nanoparticles showed remarkable antioxidant and anti-inflammatory activity. It was discovered that the cytotoxic effect was less harmful, demonstrating biocompatibility. Rosa jasminum extract of AgNps showed good anti-inflammatory efficacy in the EA and BSA assays. Conclusion: From our study we concluded that Silver nanoparticles were created using rosa and jasminum extract, and the nanoparticles displayed impressive anti-inflammatory.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74465172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.12
Samera F. AlBasri
Case Summary: A 25-year-old woman who was referred to our hospital at 38 week’s gestation from another hospital as a case of placenta previa with possible accreta. She underwent cesarean hysterectomy and encountered sever postpartum hemorrhage that required massive transfusion of blood products and arterial embolization which was done and saved her life without further morbidity. Conclusion: With increased prevalence of placenta accreta spectrum, arterial embolization facility should be an integral part of treatment protocol to save maternal life.
{"title":"Arterial Embolization; A Lifesaving Solution in Placenta Accreta spectrum Post Hysterectomy: A Case Report","authors":"Samera F. AlBasri","doi":"10.5455/jcmr.2023.14.01.12","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.12","url":null,"abstract":"Case Summary: A 25-year-old woman who was referred to our hospital at 38 week’s gestation from another hospital as a case of placenta previa with possible accreta. She underwent cesarean hysterectomy and encountered sever postpartum hemorrhage that required massive transfusion of blood products and arterial embolization which was done and saved her life without further morbidity. Conclusion: With increased prevalence of placenta accreta spectrum, arterial embolization facility should be an integral part of treatment protocol to save maternal life.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84615427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.29
Sadhana Karunakaran, P. Sinduja, R. Priyadharshini, P. Ganesh
Background: Dental caries still remain a highly prevalent disease among all age groups especially children. It is caused due to repetitive and/or prolonged demineralization of tooth enamel caused by exposure to low pH from organic acids produced by acidogenic oral bacteria during fermentation of dietary carbohydrates. Streptococcus mutans is a facultative anaerobic , gram positive cocci commonly found in the human oral cavity which plays an important role in causing dental caries. Moringa oleifera Lam. (drumstick tree) is a Moringaceae family member which possesses a variety of advantageous biological properties, such as immunomodulatory, anticancer, antiulcer and antimicrobial properties. Thymus vulgaris is a pleasant smelling perennial shrub which has a direct influence on many bacteria species. The use of combinations of these two EOs and their components are thus a new approach to increase the antimicrobial efficacy of EOs , taking advantage of their synergistic and additive effects. Materials and methods: The broth microdilution method was used to determine the minimum inhibitory concentration(MIC) of the essential oils. The MIC of Moringa, Thyme and combination of the both essential oils against S.mutans which were used in the assay were assessed at a different concentration level. Results: The antimicrobial activity of M.oleifera, T.vulgaris and combination of both the essential oils was proven with the MIC value of 2.5%v/v, 0.03906% and 0.03906% respectively. Conclusion: The combination of Moringa oleifera and Thymus vulgaris essential oil can be used as a good antimicrobial agent to treat various Streptococci borne oral infections. Further incorporation of this oil into the drug formulations is also recommended to treat S.mutans borne oral as well as systemic infections.
{"title":"Synergistic Activity of Moringa Oleifera and Thyme Vulgaris Essential Oil Against Streptococcus Mutans: An Observational Study","authors":"Sadhana Karunakaran, P. Sinduja, R. Priyadharshini, P. Ganesh","doi":"10.5455/jcmr.2023.14.01.29","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.29","url":null,"abstract":"Background: Dental caries still remain a highly prevalent disease among all age groups especially children. It is caused due to repetitive and/or prolonged demineralization of tooth enamel caused by exposure to low pH from organic acids produced by acidogenic oral bacteria during fermentation of dietary carbohydrates. Streptococcus mutans is a facultative anaerobic , gram positive cocci commonly found in the human oral cavity which plays an important role in causing dental caries. Moringa oleifera Lam. (drumstick tree) is a Moringaceae family member which possesses a variety of advantageous biological properties, such as immunomodulatory, anticancer, antiulcer and antimicrobial properties. Thymus vulgaris is a pleasant smelling perennial shrub which has a direct influence on many bacteria species. The use of combinations of these two EOs and their components are thus a new approach to increase the antimicrobial efficacy of EOs , taking advantage of their synergistic and additive effects. Materials and methods: The broth microdilution method was used to determine the minimum inhibitory concentration(MIC) of the essential oils. The MIC of Moringa, Thyme and combination of the both essential oils against S.mutans which were used in the assay were assessed at a different concentration level. Results: The antimicrobial activity of M.oleifera, T.vulgaris and combination of both the essential oils was proven with the MIC value of 2.5%v/v, 0.03906% and 0.03906% respectively. Conclusion: The combination of Moringa oleifera and Thymus vulgaris essential oil can be used as a good antimicrobial agent to treat various Streptococci borne oral infections. Further incorporation of this oil into the drug formulations is also recommended to treat S.mutans borne oral as well as systemic infections.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84664221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.34
Ahmed Almansour
Background & Aims: Injuries to the anterior cruciate ligament (ACL) are among the most common types of injuries that occur during sport activities. Some studies reported that the dominance leg is significant predictor for ACL injuries. However, it is unclear whether the dominant or non-dominant leg impacts functional status and psychological readiness to return to sport after ACL. The purpose of this study was to determine if there are difference in functional performance and psychological readiness to return to sport between individuals who injured their dominant leg and non-dominant leg after 1-10 years following ACL reconstruction. Methods: A cross-sectional study of 50 participants between 20 and 38 years was conducted, to investigate individuals who injured their dominant leg (n=25) and non-dominant leg (n=25) after 1-10 years following ACL reconstruction. All participants complete Anterior Cruciate Ligament Return to Sport after Injury (ACL-RSI), the Lower Extremity Functional Scale (LEFS) questionnaires and Fear Avoidance Belief Questionnaire physical activity (FABQ-PA). Results: No significant difference was found between the dominant leg and non-dominant leg groups in ACL-RSI, LEFS and FABQ-PA (U = 256, p = 0.27; U = 314.5, p = 0.96, and U=279.5 p=0.52) respectively. Conclusions: While it is essential to investigate the functional performance and patient's psychological state, dominance vs non- dominance leg does not influence these outcomes 1-10 years following ACL reconstruction. Therefore, injuries either dominance or non-dominance leg demonstrate equal long-term improvement. To enhance rehabilitation and optimize long-term functional outcomes for individual undergoing ACL reconstruction, future research should investigate other factors that impact recovery and return-to-sport outcomes.
{"title":"Functional performance and psychological readiness after 1–10 years ACL reconstruction: A comparison between dominant and nondominant legs","authors":"Ahmed Almansour","doi":"10.5455/jcmr.2023.14.03.34","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.34","url":null,"abstract":"Background & Aims: Injuries to the anterior cruciate ligament (ACL) are among the most common types of injuries that occur during sport activities. Some studies reported that the dominance leg is significant predictor for ACL injuries. However, it is unclear whether the dominant or non-dominant leg impacts functional status and psychological readiness to return to sport after ACL. The purpose of this study was to determine if there are difference in functional performance and psychological readiness to return to sport between individuals who injured their dominant leg and non-dominant leg after 1-10 years following ACL reconstruction. Methods: A cross-sectional study of 50 participants between 20 and 38 years was conducted, to investigate individuals who injured their dominant leg (n=25) and non-dominant leg (n=25) after 1-10 years following ACL reconstruction. All participants complete Anterior Cruciate Ligament Return to Sport after Injury (ACL-RSI), the Lower Extremity Functional Scale (LEFS) questionnaires and Fear Avoidance Belief Questionnaire physical activity (FABQ-PA). Results: No significant difference was found between the dominant leg and non-dominant leg groups in ACL-RSI, LEFS and FABQ-PA (U = 256, p = 0.27; U = 314.5, p = 0.96, and U=279.5 p=0.52) respectively. Conclusions: While it is essential to investigate the functional performance and patient's psychological state, dominance vs non- dominance leg does not influence these outcomes 1-10 years following ACL reconstruction. Therefore, injuries either dominance or non-dominance leg demonstrate equal long-term improvement. To enhance rehabilitation and optimize long-term functional outcomes for individual undergoing ACL reconstruction, future research should investigate other factors that impact recovery and return-to-sport outcomes.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75945053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.20
Harshitha Nagothu, Koushik Yetukuri, R. Nadendla
A system of pharmacovigilance is a field of pharmacological sciences that deals with the Adverse Events Reaction reporting produced by medical devices and or drugs. One of the possible public health problems is an adverse event, which needs ongoing recording, assessment, and surveillance. Drug regulations have improved and got stronger since the 1937 sulphanilamide tragedy and the1960 thalidomide disaster. As such response, a Pharmacovigilance System was developed, which is capable of receiving, diagnosing, evaluating, monitoring, and mitigating harmful effects of medical products. The Central Drug Standard Control Organization-CDSCO regulates India's pharmacovigilance system, whereas the United States Food and Drug Administration-USFDA regulates the US pharmacovigilance system. In India, the pharmacovigilance programme monitors adverse drug responses. India has a Pharmacovigilance Program in place to track adverse drug reactions. The United States likewise has strict laws in place to strengthen Food & Drug Administration (FDA) pharmacovigilance requirements. (WHO) -World Health Organization established an International Monitoring System in collaboration with (UMC) Uppsala Monitoring Centre.
{"title":"Comparitive Study of Pharmacovigilance System in India and USA","authors":"Harshitha Nagothu, Koushik Yetukuri, R. Nadendla","doi":"10.5455/jcmr.2023.14.02.20","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.20","url":null,"abstract":"A system of pharmacovigilance is a field of pharmacological sciences that deals with the Adverse Events Reaction reporting produced by medical devices and or drugs. One of the possible public health problems is an adverse event, which needs ongoing recording, assessment, and surveillance. Drug regulations have improved and got stronger since the 1937 sulphanilamide tragedy and the1960 thalidomide disaster. As such response, a Pharmacovigilance System was developed, which is capable of receiving, diagnosing, evaluating, monitoring, and mitigating harmful effects of medical products. The Central Drug Standard Control Organization-CDSCO regulates India's pharmacovigilance system, whereas the United States Food and Drug Administration-USFDA regulates the US pharmacovigilance system. In India, the pharmacovigilance programme monitors adverse drug responses. India has a Pharmacovigilance Program in place to track adverse drug reactions. The United States likewise has strict laws in place to strengthen Food & Drug Administration (FDA) pharmacovigilance requirements. (WHO) -World Health Organization established an International Monitoring System in collaboration with (UMC) Uppsala Monitoring Centre.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76428441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The objective of this study is to contribute to the valorization of one of Ephedraceae family species, Ephedra alata, at the level of Ouenza region in Tébessa city, which is situated in the North-East of Algeria. This plant is endowed with a great pharmacological importance and known by its resistance to drought. This work begins with an ethnobotanical survey. Its objective is to learn about the use of Ephedra alata in herbal medicine, and then to carry out a phytochemical study (chemical screening). According to the ethnobotanical survey, the pharmacological importance of the plant seems to be ignored by a large part of the population. The chemical screening has shown the presence of various secondary metabolites in the plant’s aerial part, such as alkaloids, polyphenols, tannins, saponosides and terpenes. Therefore, regarding these last results, it is appropriate to confirm to what extent Ephedra alata can be useful, particularly, by its phytotherapeutic participation, namely the harvest period, the used part and the way of use. Finally to avoid the progressive extinction of this species, it is necessary to intensify the actions of knowledge and prevention for the preservation and the reconquest of biodiversity.
{"title":"Ethnobotanical study of a Medicinal Plant -Ephedra alata- In the North-East of Algeria","authors":"Fellah Imene, Bouzata Chouhaira, Touil Wided, Gherib Imane","doi":"10.5455/jcmr.2023.14.01.04","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.04","url":null,"abstract":"The objective of this study is to contribute to the valorization of one of Ephedraceae family species, Ephedra alata, at the level of Ouenza region in Tébessa city, which is situated in the North-East of Algeria. This plant is endowed with a great pharmacological importance and known by its resistance to drought. This work begins with an ethnobotanical survey. Its objective is to learn about the use of Ephedra alata in herbal medicine, and then to carry out a phytochemical study (chemical screening). According to the ethnobotanical survey, the pharmacological importance of the plant seems to be ignored by a large part of the population. The chemical screening has shown the presence of various secondary metabolites in the plant’s aerial part, such as alkaloids, polyphenols, tannins, saponosides and terpenes. Therefore, regarding these last results, it is appropriate to confirm to what extent Ephedra alata can be useful, particularly, by its phytotherapeutic participation, namely the harvest period, the used part and the way of use. Finally to avoid the progressive extinction of this species, it is necessary to intensify the actions of knowledge and prevention for the preservation and the reconquest of biodiversity.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90140837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.03
S. Rajalakshmi, R. Subhasree, Rajalakshmanan Easwaramoorthy, Thiyaneswaran Nesappan
Aim: To assess the characterization, antimicrobial activity of green synthesised magnesium oxide nanoparticles using Psydium guajava leaves. Materials And Methods: Psydium guajava leaves were dried and ground, of which 2 g of the powder was used for the study.the powder was then dissolved in 100ml of distilled water. 1 mg of magnesium chloride salt was dissolved in 20 ml of distilled water. Both the solutions were mixed and subjected to centrifuge. After the preparation of the nanoparticle, it was subjected for further investigation like SEM analysis, EDAX, UV-VIs, cytotoxicity and anti microbial tests. The cytotoxicity was investigated using a brine shrimps bioassay.The number of surviving naupli cells were manually counted under dissection microscope. The antibacterial activity was examined against four bacterial strains- E.coli, E.fecalis,S.aureus,P.aurogenosa by agar well diffusion method .The inoculated plates were incubated overnight (for about 24 hours at 37 degree celsius) and the inhibition zone around the nanoparticle solution was calculated. The antimicrobial tests were carried against standard antibiotic and the results were tabulated. Results: SEM analysis showed a particle size of 70 nm and the UV -Visible spectroscopy showed a peak at 320nm confirming the presence of magnesium oxide nanoparticles that is prepared using Psydium guajava. Cytotoxicty tests revealed that 83% of the brine shrimp cells survived .The anti microbial tests revealed that the nanoparticle was effective against two micro-organisms -S.aureus and E.fecalis and their zone of inhibition was nearly equal to that of standard antibiotic against which the organisms were incubated. Conclusion: Psydium guajava synthesized magnesium nanoparticles were found to have good cytotoxicity and acceptable anti-microbial activity especially against two most commonly harbouring micro-organism(S.aureus and E.faecalis) .Hence they can be extended for use in soft tissue healing.
{"title":"Assessment of the characterization antimicrobial and green synthesis of magnesium oxide nanoparticles using Psydium guajava - in-vitro analysi","authors":"S. Rajalakshmi, R. Subhasree, Rajalakshmanan Easwaramoorthy, Thiyaneswaran Nesappan","doi":"10.5455/jcmr.2023.14.02.03","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.03","url":null,"abstract":"Aim: To assess the characterization, antimicrobial activity of green synthesised magnesium oxide nanoparticles using Psydium guajava leaves. Materials And Methods: Psydium guajava leaves were dried and ground, of which 2 g of the powder was used for the study.the powder was then dissolved in 100ml of distilled water. 1 mg of magnesium chloride salt was dissolved in 20 ml of distilled water. Both the solutions were mixed and subjected to centrifuge. After the preparation of the nanoparticle, it was subjected for further investigation like SEM analysis, EDAX, UV-VIs, cytotoxicity and anti microbial tests. The cytotoxicity was investigated using a brine shrimps bioassay.The number of surviving naupli cells were manually counted under dissection microscope. The antibacterial activity was examined against four bacterial strains- E.coli, E.fecalis,S.aureus,P.aurogenosa by agar well diffusion method .The inoculated plates were incubated overnight (for about 24 hours at 37 degree celsius) and the inhibition zone around the nanoparticle solution was calculated. The antimicrobial tests were carried against standard antibiotic and the results were tabulated. Results: SEM analysis showed a particle size of 70 nm and the UV -Visible spectroscopy showed a peak at 320nm confirming the presence of magnesium oxide nanoparticles that is prepared using Psydium guajava. Cytotoxicty tests revealed that 83% of the brine shrimp cells survived .The anti microbial tests revealed that the nanoparticle was effective against two micro-organisms -S.aureus and E.fecalis and their zone of inhibition was nearly equal to that of standard antibiotic against which the organisms were incubated. Conclusion: Psydium guajava synthesized magnesium nanoparticles were found to have good cytotoxicity and acceptable anti-microbial activity especially against two most commonly harbouring micro-organism(S.aureus and E.faecalis) .Hence they can be extended for use in soft tissue healing.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87456680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.01.27
Kaviya Selvaraj, A. Arthanari, S. Rajeshkumar
Introduction: Rose (rosa canina) is one of the flowers that are much in demand by the community because besides being an ornamental flower it can also be used as a cosmetic. Traditional medicinal herbs have seen a rebound in recent years, and as a result, pharmaceutical companies are investing heavily in developing natural medications derived from plants. Aim: To study the Anti-diabetic activity of Rose Jasmine formulation mediated silver nanoparticles. Materials and methods: The anti-diabetic activity was tested by the following inhibition of α-glucosidase at different concentrations of the prepared extract mediated with silver nanoparticles. Result: Using rosa and jasminum extract in the manufacture of silver nanoparticles, the nanoparticles showed remarkable anti-diabetic activity. It was discovered that the herbal effect was less harmful. Rosa jasminum extract of AgNps showed good anti-diabetic efficacy in the BSA assays. Conclusion: Result of this study suggest that biosynthesis of silver nano particle using rose and Jasmine showed its anti diabetic activity
{"title":"Biosynthesis Of Silver Nanoparticles Using Rose and Jasmine and Its Anti Diabetic Potential","authors":"Kaviya Selvaraj, A. Arthanari, S. Rajeshkumar","doi":"10.5455/jcmr.2023.14.01.27","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.27","url":null,"abstract":"Introduction: Rose (rosa canina) is one of the flowers that are much in demand by the community because besides being an ornamental flower it can also be used as a cosmetic. Traditional medicinal herbs have seen a rebound in recent years, and as a result, pharmaceutical companies are investing heavily in developing natural medications derived from plants. Aim: To study the Anti-diabetic activity of Rose Jasmine formulation mediated silver nanoparticles. Materials and methods: The anti-diabetic activity was tested by the following inhibition of α-glucosidase at different concentrations of the prepared extract mediated with silver nanoparticles. Result: Using rosa and jasminum extract in the manufacture of silver nanoparticles, the nanoparticles showed remarkable anti-diabetic activity. It was discovered that the herbal effect was less harmful. Rosa jasminum extract of AgNps showed good anti-diabetic efficacy in the BSA assays. Conclusion: Result of this study suggest that biosynthesis of silver nano particle using rose and Jasmine showed its anti diabetic activity","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86900652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.02.28
Medjid Nesturov, V. Pavalaki, Diana Ovsyannikova, A. Romanenko, Yu. S. Trusov
The article examines the possibilities of modern medicine in the field of early diagnosis of Parkinson’s disease. As the author points out, the pathogenesis of Parkinson’s disease is a complex mechanism that includes many different processes and mechanisms. Understanding these processes and mechanisms can help in the development of new methods of treatment and prevention of PD. Despite the fact that all aspects of the pathogenesis of PD have not been fully studied, there are a number of drugs and technologies that can slow down or reduce the manifestation of PD symptoms.
{"title":"Possibilities of Modern Medicine in the Field of Early Diagnosis of Parkinson’s Disease","authors":"Medjid Nesturov, V. Pavalaki, Diana Ovsyannikova, A. Romanenko, Yu. S. Trusov","doi":"10.5455/jcmr.2023.14.02.28","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.28","url":null,"abstract":"The article examines the possibilities of modern medicine in the field of early diagnosis of Parkinson’s disease. As the author points out, the pathogenesis of Parkinson’s disease is a complex mechanism that includes many different processes and mechanisms. Understanding these processes and mechanisms can help in the development of new methods of treatment and prevention of PD. Despite the fact that all aspects of the pathogenesis of PD have not been fully studied, there are a number of drugs and technologies that can slow down or reduce the manifestation of PD symptoms.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79567972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/jcmr.2023.14.03.27
Shaza Waggass
Objective: The objective of this study is to review the outcomes of gestational trophoblastic disease in our center, and to compare it with international figures. We will calculate the rates of remission, recurrence, and mortality. Also, we will determine the mean duration taken for normalization of β-hCG level after initiation of treatment, and the distribution of the disease by age and parity. Methods: Retrospective chart review of the patients diagnosed with gestational trophoblastic disease (GTD) and treated in King Khalid National Guard Hospital in the period between January 2000 and December 2005. Results: During the study period, there were 29 cases of gestational trophoblastic disease. The majority of the cases were non-metastatic GTD (55.2%) followed by, in decreasing order of frequency, molar pregnancy (24.1%), metastatic high-risk GTD (10.3%), metastatic low-risk GTD (6.9%) and placental-site trophoblastic tumor (3.4%). Patient's age ranged from sixteen to fifty-three years old, with the majority in the fourth decade of life (37.9%). The parity as well was highly variable from zero to fifteen, with the majority between five and ten (37.9%). Remission rate in the malignant GTD was 85.7%. There were no cases of recurrence during the follow-up period. The overall mortality rate was 3.4%. The mean duration required for normalization of β-hCG level was 10.3 weeks for molar pregnancy and 11.6 weeks for malignant GTD. Conclusion: The chemotherapy success rate, remission rate & mortality rate were similar to that reported in earlier studies. There is a need for patient education regarding strict follow-up for early detection and intervention of malignant sequelae.
{"title":"Outcomes of Gestational Trophoblastic Disease in King Khalid National Guard Hospital","authors":"Shaza Waggass","doi":"10.5455/jcmr.2023.14.03.27","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.27","url":null,"abstract":"Objective: The objective of this study is to review the outcomes of gestational trophoblastic disease in our center, and to compare it with international figures. We will calculate the rates of remission, recurrence, and mortality. Also, we will determine the mean duration taken for normalization of β-hCG level after initiation of treatment, and the distribution of the disease by age and parity. Methods: Retrospective chart review of the patients diagnosed with gestational trophoblastic disease (GTD) and treated in King Khalid National Guard Hospital in the period between January 2000 and December 2005. Results: During the study period, there were 29 cases of gestational trophoblastic disease. The majority of the cases were non-metastatic GTD (55.2%) followed by, in decreasing order of frequency, molar pregnancy (24.1%), metastatic high-risk GTD (10.3%), metastatic low-risk GTD (6.9%) and placental-site trophoblastic tumor (3.4%). Patient's age ranged from sixteen to fifty-three years old, with the majority in the fourth decade of life (37.9%). The parity as well was highly variable from zero to fifteen, with the majority between five and ten (37.9%). Remission rate in the malignant GTD was 85.7%. There were no cases of recurrence during the follow-up period. The overall mortality rate was 3.4%. The mean duration required for normalization of β-hCG level was 10.3 weeks for molar pregnancy and 11.6 weeks for malignant GTD. Conclusion: The chemotherapy success rate, remission rate & mortality rate were similar to that reported in earlier studies. There is a need for patient education regarding strict follow-up for early detection and intervention of malignant sequelae.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77282362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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