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Adolescent Substance Use, and Related Emergency Room Visits, and Continuum of Care 青少年药物使用、相关急诊室就诊和持续护理
IF 0.4 Q4 PEDIATRICS Pub Date : 2024-07-22 DOI: 10.2174/0122106766304121240718112939
Oluwadunni Adegbite, Andrew Enegela, Crystal Obiozor, Edore Onigu-Otite
Adolescence is a unique developmental period marked bybiophysiological changes and psychosocial exploration. Risk-taking behaviors,including experimentation with psychoactive substances, are common during thisperiod. Emergency room (ER) visits for adverse events related to adolescentsubstance use have increased over the last two decades. Without a continuum of carefrom the ER, significant opportunities to intervene are missed. The narrative reviewarticle aims to provide an overview of substance use during Adolescence in theUnited States, highlight related ER visits, and discuss extending care beyond the ER.A literature review was conducted to reveal historical and recent studies related toadolescent substance use trends, morbidity, and mortality patterns, as well as themuch-needed continuum of care after the ER. Our approach prioritized capturingdiverse perspectives and significant studies relevant to these themes, aiming for athorough discussion without strict adherence to systematic review methodologies.The selection of studies involved a comprehensive search across multiple databases,including PubMed, Google Scholar, and relevant academic journals. Search termswere tailored to capture studies addressing adolescent substance abuse, ER visitation,and aftercare. Studies were screened based on title, abstract, and full-text review,with a focus on relevance and significance to the review's objectives. The strategy forthis narrative review facilitated a detailed exploration of the selected themes whilealso allowing for flexibility in study selection and interpretation. National studiesindicate an overall decline in the proportions of adolescents using substancescompared to pre-COVID-19 levels. However, morbidity and mortality patterns havenot mirrored this decline. Various factors, including gender, location, and specificmental health disorders, are associated with adolescent substance use presentations.Acute care providers in emergency settings, employing protocols like SBIRT, cansignificantly impact outcomes by facilitating appropriate screening and referral toaftercare treatment programs. Identification of barriers to care, such as stigma andsocial determinants of health, is important in formulating tailored interventions.While acute care provides an opportunity to intervene and initiate treatment, acontinuum of care is essential to reduce morbidity and mortality patterns amongadolescents with substance use.
青春期是一个独特的发育时期,其特点是生理变化和社会心理探索。在这一时期,冒险行为(包括尝试使用精神活性物质)很常见。在过去二十年里,因青少年使用药物导致不良事件而到急诊室(ER)就诊的人数不断增加。如果没有从急诊室开始的持续护理,就会错失重要的干预机会。这篇叙述性综述文章旨在概述美国青少年时期的药物使用情况,强调相关的急诊就诊情况,并讨论将护理延伸到急诊室之外的问题。我们进行了文献综述,以揭示与青少年药物使用趋势、发病率和死亡率模式相关的历史和最新研究,以及急诊室之后亟需的持续护理。我们的方法是优先捕捉与这些主题相关的不同观点和重要研究,旨在进行彻底讨论,而不严格遵循系统性综述方法。研究的选择涉及多个数据库的全面搜索,包括 PubMed、谷歌学术和相关学术期刊。检索词专门针对青少年药物滥用、急诊室探视和善后护理方面的研究。根据标题、摘要和全文综述对研究进行筛选,重点关注与综述目标的相关性和重要性。叙事性综述的策略有助于对所选主题进行详细探讨,同时也允许对研究进行灵活选择和解释。全国性研究表明,与 COVID-19 前的水平相比,青少年使用药物的比例总体有所下降。然而,发病率和死亡率的模式并没有反映出这种下降。包括性别、地点和特定心理健康疾病在内的各种因素都与青少年使用药物的情况有关。在急诊环境中,急诊护理人员采用 SBIRT 等方案,可以通过促进适当的筛查和转诊至后续护理治疗项目,对治疗结果产生重大影响。虽然急诊护理为干预和启动治疗提供了机会,但持续的护理对于降低药物滥用青少年的发病率和死亡率至关重要。
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引用次数: 0
Psychosomatic Problems Among Adolescents During/Post theCOVID-19 Pandemic: A Systematic Review COVID-19 大流行期间/之后青少年的心身问题:系统回顾
IF 0.4 Q4 PEDIATRICS Pub Date : 2024-07-03 DOI: 10.2174/0122106766307916240626104350
M. Shukla, Niti Upadhyay
This systematic review aimed at exploring the impact of thecoronavirus pandemic on adolescents’ psychosomatic problems and whether thepandemic differentially impacted different genders.It also explored whether particular clusters of psychosomatic problems, viz.,psychological, somatic, and musculoskeletal, manifested more post-pandemic thanbefore. An extensive search of eight electronic databases for studiespublished/conducted between 2014-2018 for pre-pandemic prevalence ofpsychosomatic problems among adolescents (11-17 years) and for studies publishedand conducted between 2019-2023 during/post-pandemic prevalence resulted in thefinal selection of 38 studies. This included 25 pre-pandemic studies, six studiespublished and conducted during/after the pandemic, and seven studies that reportedpre-post-pandemic comparison. The review was reported following PRISMAguidelines. ROBINS-E tool was used for assessing the risk of bias while the JBICritical Appraisal Tools were used to assess study quality.Findings showed that sleep problems and headaches dominated adolescentpsychosomatic problems pre-pandemic. Sleep problems continued to be the mostcommon problem post-pandemic, followed by stomach ache and feeling low,dizziness, irritability, appetite loss, tension, and difficulty concentrating. In general,females reported more psychosomatic symptoms, though limited research exploredgender differences. Only one study found improved psychosomatic health postpandemic, more so for boys than girls. Psychological complaints increased postpandemic; however, results were mixed about somatic and musculoskeletalcomplaints after the pandemic. Some studies found no change in post-pandemicpsychosomatic symptoms.Gender-specific, tailored training programs are crucial for enhancingresilience and coping to mitigate the impact of the pandemic on adolescents’psychosomatic health.
本系统性综述旨在探讨冠状病毒大流行对青少年心身问题的影响,以及大流行是否对不同性别产生了不同影响,还探讨了大流行后心身问题(即心理、躯体和肌肉骨骼问题)是否比大流行前表现得更为突出。我们在八个电子数据库中广泛搜索了2014-2018年期间发表/开展的青少年(11-17岁)心身问题流行前的研究,以及2019-2023年期间发表/开展的青少年心身问题流行期间/流行后的研究,最终选出了38项研究。其中包括 25 项大流行前的研究、6 项在大流行期间/之后发表和进行的研究,以及 7 项报告大流行前/后比较的研究。综述报告遵循了 PRISMA 准则。研究结果表明,睡眠问题和头痛是大流行前青少年的主要心身问题。大流行后,睡眠问题仍然是最常见的问题,其次是胃痛和情绪低落、头晕、易怒、食欲不振、紧张和注意力难以集中。一般来说,女性报告的心身症状较多,但探讨性别差异的研究有限。只有一项研究发现大流行后心身健康状况有所改善,男孩的改善程度高于女孩。大流行后,心理不适症状有所增加;然而,关于大流行后躯体和肌肉骨骼不适症状的研究结果却不尽相同。一些研究发现,大流行后的心身症状没有任何变化。针对不同性别的定制培训计划对于提高应变能力和应对能力以减轻大流行对青少年心身健康的影响至关重要。
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引用次数: 0
Factors Associated with Posttraumatic Stress Disorder inAdolescents Experiencing Earthquake Trauma 经历地震创伤的青少年创伤后应激障碍的相关因素
IF 0.4 Q4 Medicine Pub Date : 2024-06-11 DOI: 10.2174/0122106766308034240605043308
Fatma Özgün Öztürk
Posttraumatic Stress Disorder (PTSD) is a prevalentpsychological response among those who survive earthquakes.This study investigates the relationships between sociodemographicand clinical differences and symptoms of avoidance, re-experiencing, andhyperarousal, which are key indicators of PTSD in adolescents.Research data were collected through online surveys using a simplerandom sampling method. The sample group consisted of 178 adolescents whomet the inclusion criteria. Data were collected using the Personal InformationForm (PIF) and the Posttraumatic Stress Disorder Symptoms Scale-Self-ReportScale (PSS-SR) for Children.Of the participants, 77% were female, with a mean age of 16.99. A totalof 84.3% lived with their families. The rate of those trapped under debris duringthe earthquake was 97.2%. During the earthquake, 84.8% of adolescents wereinjured, and 25.8% lost a family member due to the earthquake. Femaleparticipants showed significantly higher total trauma, re-experiencing, andhyperarousal scores than males (p<0.05). Those physically injured during theearthquake had significantly lower total trauma and avoidance scores comparedto those not injured (p<0.05). Participants who lost a family member during theearthquake had significantly lower total trauma, re-experiencing, andhyperarousal scores compared to those who did not lose a family member(p<0.05).Females exhibited more PTSD symptoms compared to males. Thosenot injured or who did not lose a family member during the earthquake showedmore PTSD symptoms than those who experienced injury or loss.
创伤后应激障碍(PTSD)是地震幸存者普遍存在的心理反应。本研究调查了社会人口学和临床差异与青少年创伤后应激障碍的关键指标--回避、再经历和过度妄想症状之间的关系。研究数据通过在线调查收集,采用简化随机抽样方法。样本组由符合纳入标准的 178 名青少年组成。数据的收集使用了个人信息表(PIF)和儿童创伤后应激障碍症状量表-自我报告量表(PSS-SR)。共有 84.3% 的人与家人住在一起。在地震中被困在废墟中的比例为 97.2%。84.8%的青少年在地震中受伤,25.8%的青少年在地震中失去了家人。女性受试者的创伤总分、再体验得分和妄想得分明显高于男性(P<0.05)。与未受伤者相比,在地震中身体受伤者的创伤和回避总分明显较低(P<0.05)。与没有失去家人的参与者相比,在地震中失去家人的参与者的创伤总分、重新体验和过度焦虑得分明显较低(P<0.05)。在地震中没有受伤或失去家人的人比受伤或失去家人的人表现出更多的创伤后应激障碍症状。
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引用次数: 0
The Role of Identity in the Relationship between PTSD andExecutive Functioning 身份认同在创伤后应激障碍与执行功能之间关系中的作用
IF 0.4 Q4 Medicine Pub Date : 2024-06-04 DOI: 10.2174/0122106766279589240529123124
Stephanie Washburn, Reilly Branch, Ishara Jean-Francois, Steven L. Berman
The developmental period of late adolescence is whensignificant identity formation takes place, especially for college students(Erikson, 1968). However, traumatic experiences can affect identity developmentand lead to extreme identity distress. With exposure to trauma, executivefunctioning can also diminish, leading to a decrease in self-control and greatersensitivity.Although trauma affects both executive functioning and identity, thepossible direct link between identity and executive function has not beenadequately explored. Among a college sample (N = 507), those who experiencedtrauma reported higher levels of identity distress, ruminative identity exploration,and lower levels of executive functioning.It was hypothesized that identity variables plus PTSD would betterpredict executive functioning than PTSD alone. The hypothesis was supported,suggesting the incremental validity of using identity in addition to PTSD topredict executive functioning scores.Implications of this study include the need to consider identitydevelopment in the treatment and prevention of PTSD, as well as trauma history,in interventions aimed at promoting positive identity development in youth
青春期后期是身份形成的重要时期,尤其是对大学生而言(Erikson,1968 年)。然而,创伤经历会影响身份认同的发展,并导致极端的身份认同困扰。虽然创伤会影响执行功能和身份认同,但身份认同和执行功能之间可能存在的直接联系尚未得到充分探讨。在一个大学生样本(N = 507)中,经历过创伤的人报告了更高水平的身份困扰、反刍性身份探索和较低水平的执行功能。本研究的意义包括:在治疗和预防创伤后应激障碍的过程中,需要考虑身份发展以及创伤史,以促进青少年积极的身份发展。
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引用次数: 0
Review of Clinical Considerations in the Management of Adolescents with ADHD During Ramadan 斋月期间管理多动症青少年的临床注意事项回顾
IF 0.4 Q4 Medicine Pub Date : 2024-05-22 DOI: 10.2174/0122106766298494240510052101
Faraz Khan, Sarah Mohiuddin
Fasting in Ramadan, a holy month in Islam, is considered areligious obligation to Muslims after puberty. Fasting during Ramadan entailsabstinence from consuming food and liquids, as well as abstaining from otheractivities, including smoking and sexual activity, from dawn until sunset. Literatureexists regarding the management of multiple medical conditions impacted by themonth of fasting; however, limited literature exists to guide the management ofAttention-Deficit/Hyperactivity Disorder (ADHD) during Ramadan.This systematic review employed a PUBMED search which wasconducted using keywords ((ADHD) AND (Muslims)) OR ((ADHD) AND(FASTING)) OR ((ADHD) AND (RAMADAN)) OR ((RAMADAN) AND(MANAGEMENT)) and search strategies to find existing literature on ADHDmanagement during Ramadan or while fasting.Eight hundred and sixty-one results were obtained. Of these, full texts ofclinical trials, systematic reviews, reviews, randomized control trials, and metaanalysesresulted in 303 results that were screened by title or abstract for relevance tothe topic. The duplicate articles were removed. Eighty-nine results were incorporatedinto this paper, including full articles, book excerpts, and online articles.Muslim adolescents may face challenges with academic and socialfunctioning as they navigate psychosocial changes in the context of Ramadan.ADHD management options should be discussed with individuals who are planningto fast. Pharmacologic management options include continuing on the currentregimen, dose adjustment to mitigate side effect exacerbation, a change in medicationclass, or a change in medication formulation. For severe cases or cases with comorbidconditions, continued fasting may not be recommended. In these cases, the patientshould attempt to seek counsel with their community’s religious scholar incollaboration with their medication provider. Ultimately, there are limitations in theavailable data, and there is a need for further investigation into the impacts of fastingduring Ramadan on individuals with ADHD and the effectiveness of interventions topromote treatment adherence.
斋月是伊斯兰教的神圣月份,斋戒被认为是穆斯林在青春期后的一项宗教义务。斋月期间的斋戒要求从黎明到日落不进食、不饮水、不进行其他活动,包括吸烟和性活动。关于受斋戒月影响的多种病症的治疗已有文献记载,但指导斋戒期间注意力缺陷/多动障碍(ADHD)治疗的文献却很有限。或((ADHD)和(斋戒))。或((斋月)和(管理)))和搜索策略来查找有关斋月或斋戒期间多动症管理的现有文献。其中,临床试验、系统回顾、综述、随机对照试验和荟萃分析的全文共有 303 项结果,这些结果均通过标题或摘要筛选出与主题相关的文章。删除了重复的文章。穆斯林青少年在斋月期间可能会面临学业和社会功能方面的挑战,因为他们要适应社会心理的变化。药物治疗方案包括继续目前的治疗方案、调整剂量以减轻副作用的加重、改变药物类别或改变药物配方。对于严重病例或有合并症的病例,可能不建议继续禁食。在这种情况下,患者应尝试与药物提供者合作,向所在社区的宗教学者寻求建议。归根结底,现有数据还存在局限性,需要进一步调查斋月期间禁食对多动症患者的影响以及促进坚持治疗的干预措施的有效性。
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引用次数: 0
Family Functioning and Unmet Mental Health Needs among School-Aged Youth 学龄青少年的家庭功能和未满足的心理健康需求
IF 0.4 Q4 Medicine Pub Date : 2024-05-14 DOI: 10.2174/0122106766286711240509061416
Kammarauche Aneni, Soyon Kim, Jenny Meyer, Isabella Gomati de la Vega, Uzochukwu Imo, H. Onyeaka, Philip Baiden, Joseph Woolston
Unmet mental health needs can lead to worsening outcomes inyouth. Given that youth depend on family for access to mental health services, and positivefamily functioning is associated with improved health outcomes, understanding theassociation between family-level factors and youth’s unmet mental health needs is essentialto inform inclusive solutions.This study aimed to examine the association between family functioning(parental aggravation, parent-child communication, family resilience) and unmet mentalhealth needs among school-aged youth.A cross-sectional analysis of the combined 2019-2020 National Survey onChildren’s Health (NSDH) dataset was performed (n=9,204). Bivariate and multivariatelogistic regression models were used to examine the association between unmet mentalhealth needs (primary outcome) and family functioning using three explanatory variables,parental aggravation, parent-child communication, and family resilience. We also examinedage-related differences in these associations between children aged 6-11 and adolescentsaged 12-17.The weighted proportion of youth with reported unmet mental health needs was18%. Weighted unadjusted analyses showed that low family resilience was associated with60% higher odds of unmet mental health needs, while parental aggravation and poor parentchildcommunication were not associated with unmet mental health needs. After adjustingfor potential confounders, low family resilience was associated with 50% higher odds ofunmet mental health needs among school-aged youth (AOR=1.54, 95% CI: 1.15-2.07).Being Black (AOR=2.28, 95% CI: 1.41-3.69), younger (AOR=0.95, 95% CI: 0.91-0.99),lacking consistent health insurance (AOR=2.64, 95% CI: 1.59-4.38), and having a motherwith poor maternal health (AOR=1.82, 95% CI: 1.36-2.46), were also associated withunmet mental health needs. Among children aged 6-11 years, low family resilience, beingBlack, lacking consistent insurance, and having a mother with poor maternal health wereassociated with unmet mental health needs (all p’s < 0.05). Similarly, among adolescentsaged 12-17 years, low family resilience, being Black, lacking consistent insurance, andhaving a mother with poor maternal health were associated with unmet mental health needs(all p < 0.05). Having a parent with a college education was associated with lower odds ofunmet mental health needs among children (6-11 years), but not adolescents (12-17 years).Our findings have suggested an association between low family resilience andunmet mental health needs among school-aged youth. Since families are an integral part ofmeeting youth’s needs, applying approaches to addressing unmet mental health needs thatconsider family resilience and parental well-being is imperative. Identifying and addressingfactors contributing to unmet health needs barriers may help address existing racialdisparities.
未得到满足的心理健康需求会导致青少年的健康状况恶化。鉴于青少年依赖家庭获得心理健康服务,而积极的家庭功能与健康结果的改善相关,因此了解家庭层面的因素与青少年未满足的心理健康需求之间的关联对于提供包容性的解决方案至关重要。本研究旨在考察学龄青少年的家庭功能(父母加重负担、亲子沟通、家庭复原力)与未满足的心理健康需求之间的关联。我们使用双变量和多变量逻辑回归模型,利用三个解释变量,即父母加重、亲子沟通和家庭复原力,研究了未满足的心理健康需求(主要结果)与家庭功能之间的关联。我们还研究了 6-11 岁儿童和 12-17 岁青少年之间与年龄相关的差异。加权未调整分析表明,家庭复原力低与心理健康需求未得到满足的几率高出 60% 有关,而父母情绪激动和亲子沟通不畅与心理健康需求未得到满足无关。在对潜在的混杂因素进行调整后,低家庭复原力与学龄青少年未满足心理健康需求的几率高出 50%有关(AOR=1.54,95% CI:1.15-2.07)。黑人(AOR=2.28,95% CI:1.41-3.69)、年轻(AOR=0.95,95% CI:0.91-0.99)、缺乏稳定的医疗保险(AOR=2.64,95% CI:1.59-4.38)、母亲健康状况差(AOR=1.82,95% CI:1.36-2.46)也与心理健康需求未得到满足有关。在 6-11 岁的儿童中,家庭复原力低、单身、没有稳定的保险以及母亲健康状况差都与心理健康需求未得到满足有关(所有 P 均小于 0.05)。同样,在 12-17 岁的青少年中,家庭复原力低、黑人、没有稳定的保险以及母亲健康状况差也与心理健康需求未得到满足有关(所有 p 均小于 0.05)。父母一方受过大学教育与儿童(6-11 岁)心理健康需求未得到满足的几率较低有关,但与青少年(12-17 岁)无关。由于家庭是满足青少年需求不可或缺的一部分,因此在解决未满足的心理健康需求时,必须考虑到家庭复原力和父母的福祉。识别和解决导致未满足健康需求障碍的因素可能有助于解决现有的种族差异。
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引用次数: 0
Impulsivity: A Transdiagnostic Approach to Understanding Adolescent Substance Use 冲动:了解青少年药物使用的跨诊断方法
IF 0.4 Q4 Medicine Pub Date : 2024-05-14 DOI: 10.2174/0122106766297440240430133940
Bishal Lamichhane, Zishen Li, Ashutosh Sabharwal, Nidal Moukaddam
Impulsivity, characterized by the tendency to act onimpulse without consideration for consequences, has been implicated in healthdisorders such as problematic substance use among adolescents. Understandingimpulsivity's nature, clinical manifestations, quantification, and management in aclinical context could help address underlying disorders.We reviewed previous studies where different impulsivity dimensionswere identified and explored the manifestations of impulsivity across conditionscharacterized by high impulsivity. Similarly, we pursued a literature search onvarious factors influencing impulsivity, methods employed to quantify them, andcommonly used treatments for impulsivity control.The multidimensional and transdiagnostic nature of impulsivity wasacknowledged across several studies. Various health disorders such as substanceuse disorders, borderline personality disorder, and attention-deficit/hyperactivitydisorder implicated impulsivity, even among the adolescent groups. We identifiedbiological, psychological, and environmental factors influencing impulsivity. Wealso present the commonly employed approaches to quantifying impulsivity andnew measurement approaches under active investigation that are relevant incharacterizing impulsivity in adolescents. Treatment options to manageimpulsivity were also reviewed and are presented in this work.This work offers a comprehensive understanding of impulsivity asone of the underlying factors in adolescent substance use and related healthdisorders, emphasizing factors affecting impulsivity, approaches formeasurement, and implications of high impulsivity on mental health andbehaviors.
冲动是一种不考虑后果、凭一时冲动行事的倾向,它与青少年问题药物使用等健康障碍有关。了解冲动的性质、临床表现、量化以及在临床环境中的管理有助于解决潜在的疾病问题。我们回顾了以前的研究,这些研究确定了不同的冲动维度,并探讨了冲动在以高冲动性为特征的各种情况下的表现。同样,我们还对影响冲动的各种因素、量化这些因素的方法以及控制冲动的常用治疗方法进行了文献检索。即使在青少年群体中,各种健康疾病,如药物滥用症、边缘型人格障碍和注意力缺陷/多动障碍也与冲动有关。我们发现了影响冲动的生物、心理和环境因素。我们还介绍了量化冲动性的常用方法,以及正在积极研究的与描述青少年冲动性相关的新测量方法。本研究对冲动性作为青少年药物使用和相关健康障碍的基本因素之一进行了全面的了解,强调了影响冲动性的因素、测量方法以及高冲动性对心理健康和行为的影响。
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引用次数: 0
Reduced Stress among COVID-Symptomatic Undergraduates: Act With Awareness, Nonjudgment, and Nonreactivity as Key Facets of Mindfulness 减轻有 COVID 症状的大学生的压力:以觉察、不判断和不反应作为正念的关键要素
IF 0.4 Q4 Medicine Pub Date : 2024-05-13 DOI: 10.2174/0122106766288982240509041026
Zoe Sirotiak, Jenna L. Adamowicz, E. B. Thomas
Associations between mindfulness and improved physicaland psychological health have been established, but COVID-19 presents a novelcontext. This study examined the relationship between individual mindfulnessfacets and general stress among college students experiencing at least onesymptom of acute COVID-19 infection in the context of the pandemic.Five hundred sixteen university students experiencing at least oneCDC-identified COVID-19 symptom completed measures of general stress,mindfulness, and somatic symptoms in 2020-2021 during the COVID-19pandemic following IRB approval and informed consent.Associations between mindfulness and improved physical and psychological health have been established, but COVID-19 presents a novel context. This study examined the relation between individual mindfulness facets and general stress among college students experiencing at least one symptom of acute COVID-19 infection in the context of the pandemic.The act with awareness, nonjudgment, and nonreactivity facets ofmindfulness were associated with general stress. In total, the model accounted forover half of the variance in general stress (R2 = 0.51, p < 0.001).Mindfulness may be particularly important in explaining generalstress among college students reporting a symptom of COVID-19. Mindfulnessmay benefit college students as the pandemic continues to unfold, and monitoringone’s physical health remains a primary mitigation strategy. These results mayalso inform understanding and responses to future public health emergencies inwhich monitoring somatic symptoms is encouraged by public health officials tocontain the spread.
正念与改善生理和心理健康之间的关系已经得到证实,但 COVID-19 提出了一个新的背景。这项研究考察了在大流行背景下,至少出现一种 COVID-19 急性感染症状的大学生中,个人正念面与一般压力之间的关系。本研究考察了在大流行背景下至少出现一种急性 COVID-19 感染症状的大学生中,正念的个体层面与一般压力之间的关系。正念在解释报告 COVID-19 症状的大学生的一般压力方面可能尤为重要。随着大流行病的不断发展,监测身体健康仍然是一种主要的缓解策略,正念可能会使大学生受益。这些结果还可能有助于理解和应对未来的公共卫生突发事件,在这种情况下,公共卫生官员会鼓励监测躯体症状以控制传播。
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引用次数: 0
PANDAS: Twenty-Five Years Later PANDAS:二十五年后
IF 0.4 Q4 Medicine Pub Date : 2024-03-20 DOI: 10.2174/0122106766298492240320044542
Federico Cardelle-Pérez, María Ángeles Díaz-Caneja Greciano
It has been 25 years since the definition of the conceptof Pediatric Autoimmune Neuropsychiatric Disorders Associated withStreptococcal Infections (PANDAS). The abrupt onset of neuropsychiatricsymptoms requires a comprehensive differential diagnosis involvingcomplementary tests and optimal treatment selection.This paper describes aspects related to the diagnosis and clinicalmanagement of PANDAS. A clinical perspective is developed starting from anexample that meets the Swedo's criteria.A comprehensive approach, including interdisciplinary managementand urgent evaluation of potential organic causes, is crucial for effectivetreatment. Treatment decisions should consider severity, symptoms, and availableevidence. Collaboration with neuropediatric or neurological services is needed.ASLO/anti-DNase B and 25-OH-Vitamin D tests are valuable for atypicalOCD/Tic presentations, always maintaining a broader organic screening.
自链球菌感染相关小儿自身免疫性神经精神障碍(PANDAS)这一概念确定以来,已有25年的历史。神经精神症状的突然出现需要进行全面的鉴别诊断,包括辅助检查和最佳治疗选择。本文从符合瑞典标准的病例出发,阐述了临床观点。综合方法,包括跨学科管理和对潜在器质性病因的紧急评估,对于有效治疗至关重要。治疗决定应考虑严重程度、症状和现有证据。ASLO/抗-DNase B和25-OH-维生素D检测对非典型OCD/Tic表现很有价值,但应始终坚持进行更广泛的器质性筛查。
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引用次数: 0
Comparative Associations between Substances Used with Depression and Anxiety in a Sample of High School Students in Turkey 土耳其高中生样本中使用的物质与抑郁和焦虑之间的关联比较
IF 0.4 Q4 Medicine Pub Date : 2024-03-05 DOI: 10.2174/0122106766257259240229070230
Ali Unlu, Parna Prajapati, Mariam Rahmani, Andres Pumariega
To explore the associations between the type and theamount of substances used with depression and anxiety symptoms by high schoolstudents.The study data was collected by the Istanbul Department of Educationon 31,604 high school students which was a survey of 66 questions administeredin the school setting. The primary questions and sub-questions on anxiety anddepression scores were added to generate a scaled score. Specific substances usedby the participants were used to explore the relationship between substance useand depression and anxiety scores by using multinomial logistic regressionmodels. Two regression models were analyzed, one for each dependent variable,keeping the significance level at 0.05. Odds ratios were calculated to explore theassociation between depression and anxiety scores and specific substance useamong the youth.The participants with low levels of anxiety were at an increased odds ofusing heavy amounts of sleep pills (OR=1.6) and alcohol (OR=1.3) as comparedto those without anxiety. In addition to sleep pills and alcohol, illicit substancessuch as LSD and inhalant use were also seen in the participants with higher levelsof anxiety. The participants with low levels of depression were found to be at anincreased odds of using sleep pills (OR=1.8) and alcohol (OR=1.3). In addition tothis pattern of substance use, participants with higher levels of depression werealso found to be heavy cocaine users, low inhalant users, heavy steroid users, andlow alcohol users. A decrease in the use of homemade brews was seen in theparticipants with low and high levels of depression as compared to those whodidn’t have any depressive symptoms.A unique pattern of drug and alcohol use was found in theparticipants experiencing varying levels of anxiety and depression.
研究数据由伊斯坦布尔教育局收集,对象为 31604 名高中生,在学校环境中进行了一项包含 66 个问题的调查。主问题和分问题的焦虑和抑郁得分相加得出一个标度分数。利用多项式逻辑回归模型,对参与者使用的特定药物进行分析,以探讨药物使用与抑郁和焦虑得分之间的关系。分析了两个回归模型,每个因变量一个,显著性水平保持在 0.05。与不焦虑的参与者相比,焦虑程度低的参与者使用大量安眠药(OR=1.6)和酒精(OR=1.3)的几率更高。除安眠药和酒精外,焦虑程度较高的参与者还使用迷幻药和吸入剂等非法药物。抑郁程度较低的参与者使用安眠药(OR=1.8)和酒精(OR=1.3)的几率增加。除了这种药物使用模式外,抑郁程度较高的参与者还被发现大量使用可卡因、少量使用吸入剂、大量使用类固醇和少量饮酒。与没有任何抑郁症状的参与者相比,抑郁程度低和抑郁程度高的参与者使用自酿啤酒的情况有所减少。
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引用次数: 0
期刊
Adolescent Psychiatry
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