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A Rare Tumor in the Neck of a Child: Plexiform Neurofibroma 儿童颈部罕见肿瘤:丛状神经纤维瘤
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-12-01 DOI: 10.4274/tao.2021.2021-3-10
Siti Sarah Mohd Ramli, G. See, F. Zaki, S. M. Md Pauzi, Mohamad Fariz Bin Amri
Plexiform neurofibroma represents an uncommon variant of neurofibromatosis type 1, constituting only 5%–30% of all cases. Plexiform neurofibroma is usually diagnosed during childhood and arises from multiple nerves, manifesting as bulging and deforming masses that can also involve connective tissue and skin folds. We report a case of a two-year-old girl who presented with worsening stridor since birth and later exhibited progressively increasing left neck swelling at the age of 10 months old. Ultrasound and magnetic resonance imaging (MRI) showed a lobulated solid mass in the left deep neck space extending to the midline and having a mass effect on the airway with involvement of the supraglottic region. Tracheostomy was done, and a biopsy of the supraglottic lesion revealed a plexiform neurofibroma. The patient was conservatively managed after a discussion with her parents concerning the associated potential of operative morbidity. The patient’s parents had learned about tracheostomy care, and the patient was scheduled for yearly MRI surveillance. MRI was performed again three months after the initial diagnosis and showed stable lesion. Plexiform neurofibroma is a slow-growing tumor. A treatment decision must consider the benefits of surgery and the morbidity of the progressing disease. Hence, airway management is crucial prior to the final decision of such cases.
丛状神经纤维瘤是一种少见的1型神经纤维瘤病,仅占所有病例的5%-30%。丛状神经纤维瘤通常在儿童时期被诊断出来,起源于多个神经,表现为肿胀和变形的肿块,也可累及结缔组织和皮肤褶皱。我们报告一个两岁的女孩谁提出恶化喘出生后,后来表现出逐渐增加左颈部肿胀在10个月大的情况下。超声和磁共振成像(MRI)显示左侧深颈空间分叶状实性肿块,延伸至中线,对气道有肿块效应,累及声门上区。气管切开术,声门上病变活检显示为丛状神经纤维瘤。在与父母讨论了手术并发症的相关可能性后,对患者进行了保守治疗。患者的父母已经了解了气管切开术的护理,并计划每年对患者进行MRI监测。初次诊断后3个月再次行MRI,病变稳定。丛状神经纤维瘤是一种生长缓慢的肿瘤。治疗决定必须考虑手术的益处和疾病进展的发病率。因此,在此类病例的最终决定之前,气道管理是至关重要的。
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引用次数: 1
Mastoid Emissary Vein Canal Incidence and Its Relationship with Jugular Bulb and Sigmoid Sulcus Anatomical Variations 乳突隐静脉管的发生率及其与颈球、乙状窦解剖变异的关系
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-12-01 DOI: 10.4274/tao.2021.2021-4-26
Rıdvan Pekçevik, Aylin Öztürk, Y. Pekçevik, O. Toka, Gülay Güçlü Aslan, I. Cukurova
Objective: We aimed to investigate the mastoid emissary vein (MEV) canal incidence and to identify its relationship with jugular bulb (JB) and sigmoid sulcus anatomical variations. Methods: We retrospectively reviewed 1,300 patients with temporal bone computed tomography (CT) scans in January 2016 to March 2020. The presence and the diameter of the MEV canal, and the anatomical variations of the sigmoid sulcus and the JB were reviewed by two radiologists. High riding JB, JB diverticulum, dehiscent JB, and anterior and lateral protrusion of the sigmoid sulcus were evaluated. All variables were summarized using descriptive statistics. The differences between the groups for categorical data were investigated using the chi-square test. Numeric variables were compared with the Mann-Whitney and the Kruskal-Wallis tests. Logistic regression models were constructed. Results: The study included 1,269 patients of whom 694 were female (54.7%) and 575 were male (45.3%). Their mean age was 39.01±18.47. Among them 915 (72.1%) had the right and 871 (68.6%) had the left MEV canal. Men were more likely to have the MEV canal on both sides. The presence of the right and left MEV canals was associated with the ipsilateral dominant JB/sigmoid sulcus. The left MEV canal was associated with the left high riding JB and right dehiscent JB. Conclusion: This is the largest patient population reported in the literature and allows a more precise estimate of the MEV canal incidence. We also classified the diameter of the MEV canal to identify clinically relevant, prominent MEV incidence. This is also the first study to demonstrate a relationship between the presence of the MEV canal, and the JB and sigmoid canal variations. Since both the prominent MEV and the JB variations may be symptomatic, knowing this association between them may have clinical relevance.
目的:探讨乳突透射静脉(MEV)管的发生率,并探讨其与颈静脉球(JB)和乙状窦沟的解剖变异之间的关系。方法:我们回顾性分析了2016年1月至2020年3月1,300例颞骨CT扫描患者。两位放射科医生回顾了MEV管的存在和直径,以及乙状结肠沟和JB的解剖变化。评估高骑型JB、JB憩室、JB开裂、乙状结肠前突及外侧突。所有变量采用描述性统计进行汇总。分类资料组间差异采用卡方检验。数值变量与Mann-Whitney检验和Kruskal-Wallis检验比较。建立了Logistic回归模型。结果:共纳入1269例患者,其中女性694例(54.7%),男性575例(45.3%)。平均年龄39.01±18.47岁。其中右侧MEV管915例(72.1%),左侧MEV管871例(68.6%)。男性更有可能两侧都有MEV管。左右MEV管的存在与同侧占主导地位的JB/乙状结肠沟有关。左侧MEV管与左侧高骑性JB和右侧开裂JB相关。结论:这是文献中报道的最大的患者群体,可以更准确地估计MEV管的发生率。我们还对MEV管的直径进行了分类,以确定临床相关的、突出的MEV发生率。这也是第一个证明MEV管的存在与JB管和乙状结肠管变化之间关系的研究。由于突出的MEV和JB变异都可能是有症状的,了解它们之间的联系可能具有临床意义。
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引用次数: 4
Management of a Spontaneous Thyroid Nodule Hemorrhage Causing Acute Airway Obstruction 自发性甲状腺结节性出血致急性气道阻塞的处理
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-12-01 DOI: 10.4274/tao.2021.2021-5-23
H. Başak, L. Yücel, A. Hasanova, S. Beton
Spontaneous intrathyroidal hemorrhage (ITH) causing airway obstruction is relatively rare. We report a case with no known history of a thyroid disease that presented with an ITH causing severe airway obstruction as a life-threatening situation. A 57-year-old female patient presented to the emergency department with sudden onset of swelling of the anterior neck, severe dyspnea, and unconsciousness. Computerized tomography scan after intubation revealed a 6.2x5.3 cm mass originating from the right thyroid lobe and compressing the airway. Drainage of hematoma with right lobectomy was done. When the patient was extubated one day after the surgery the vocal cords were found to be mobile. She was discharged after two days and there was no need for further intervention during the one-month follow-up. Spontaneous life-threatening ITHs are rare entities. Immediate assessment of airway obstruction and achieving a secure airway are crucial. Besides drainage of hematoma, thyroidectomy may also be necessary.
引起气道阻塞的自发性甲状腺内出血(ITH)相对罕见。我们报告了一例无甲状腺病史的病例,该病例表现为ITH导致严重气道阻塞,危及生命。一名57岁的女性患者在急诊科就诊时突然出现前颈部肿胀、严重呼吸困难和意识不清。插管后的计算机断层扫描显示,右侧甲状腺叶有6.2x5.3厘米的肿块,压迫气道。右侧肺叶切除术引流血肿。当患者在手术后一天拔管时,发现声带是活动的。她在两天后出院,在一个月的随访中无需进一步干预。自发性危及生命的ITH是罕见的。立即评估气道阻塞并获得安全的气道至关重要。除血肿引流外,甲状腺切除术可能也是必要的。
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引用次数: 3
Otolaryngology Residents' Attitudes, Experiences, and Barriers Regarding the Medical Research. 耳鼻喉科住院医师对医学研究的态度、经历及障碍。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-09-01 Epub Date: 2021-10-15 DOI: 10.4274/tao.2021.2021-4-11
Hülya Eyigör, Cüneyt Orhan Kara

Objective: It was aimed to investigate the attitudes, experiences, and barriers towards scientific research among otolaryngology residents in Turkey.

Methods: Anonymous data were collected via an online survey. The demographic characteristics and experience in scientific research were investigated in the first section of the survey. The attitudes of participants towards scientific research and the barriers to the scientific research were examined in the second section of the survey using 17 items.

Results: The present study involved 119 otolaryngology residents continuing their education. It was determined that 68.1% of participants think that "participating in scientific research" is a part of otolaryngology training. In the present study, it was shown that the residents having journal club hours in clinics on regular basis participated in various steps of scientific research projects (p<0.05). Residents stated that they participated in the "literature review" stage of the preparation of a scientific publication (mean value of 2.58±1.88) most and in "verbal presentation in a congress" least (mean value of 0.74±1.44). It was determined that 80.7% of participants have not attended in any training on scientific research. It was found that the residents receiving structured scientific research training participated more in steps of scientific research projects which was statistically significantly (p<0.05).

Conclusion: In our country, otolaryngology residents are very enthusiastic about having research education and participating in researches. However, residency students frequently have time deficiency, lack of knowledge-skill, and lack of financial support. Dedicated time should be allocated for research training and practice in specialty programs. Journal club activities should be organized on regular basis and integrated with research education. On the other hand, the scholarly activities of residents should be supported by means of various countrywide educational activities on research training.

目的:调查土耳其耳鼻喉科住院医师对科学研究的态度、经历和障碍。方法:采用在线调查方式收集匿名资料。调查的第一部分调查了人口统计学特征和科研经验。调查的第二部分使用17个项目考察了参与者对科学研究的态度和科学研究的障碍。结果:本研究涉及119名耳鼻喉科住院医师继续接受教育。确定68.1%的参与者认为“参加科学研究”是耳鼻喉科培训的一部分。本研究结果显示,定期在门诊参加期刊俱乐部时数的住院医师参与科研项目的各个步骤(文献综述”阶段、科学出版物准备阶段(平均值2.58±1.88)最多,“大会口头陈述”阶段(平均值0.74±1.44)最少。确定80.7%的参与者没有参加过任何科学研究培训。结果发现,接受结构化科研培训的住院医师参与科研项目的步骤较多,差异有统计学意义(p结论:在我国,耳鼻喉科住院医师对科研教育和参与研究的热情非常高。然而,住院医师学生往往存在时间不足、缺乏知识技能和缺乏经济支持的问题。专门的时间应该分配给研究、训练和专业项目的实践。期刊社活动应定期组织,并与科研教育相结合。另一方面,应通过各种全国性的科研培训教育活动来支持居民的学术活动。
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引用次数: 1
A Patient with Severe Cervicofacial Subcutaneous Emphysema Associated with Munchausen's Syndrome: A Case Report. 重度颈面皮下肺气肿合并Munchausen综合征1例。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-09-01 Epub Date: 2021-10-15 DOI: 10.4274/tao.2021.2021-3-16
Serap Şahin Önder, Ayşe Aslı Şahin Yılmaz, Ceyhan Şahin, Zekeriya İlçe, Sevinç Kalın

Subcutaneous cervicofacial emphysema is a rare and life-threatening condition that results from various causes. In this report, we documented a case of a patient with severe subcutaneous cervicofacial emphysema a condition that falls under the umbrella of Munchausen's syndrome and discussed the workup of this patient. Thorough diagnostic investigations seeking the etiology of the condition proved unsuccessful. When faced with cases of recurring subcutaneous cervicofacial emphysema, where the root cause remains ambiguous a diagnosis of Munchausen's Syndrome should be considered.

颈面皮下肺气肿是一种罕见且危及生命的疾病,由多种原因引起。在本报告中,我们记录了一例严重的颈面皮下肺气肿患者,这种情况属于Munchausen综合征,并讨论了该患者的检查。彻底的诊断调查寻求该病的病因证明是不成功的。当面对复发的皮下颈面肺气肿的情况下,其根本原因仍然不明确的诊断Munchausen's综合征应考虑。
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引用次数: 0
Call for Emergency Action to Limit Global Temperature Increases, Restore Biodiversity, and Protect Health: Wealthy nations must do much more, much faster. 呼吁采取紧急行动限制全球气温上升,恢复生物多样性,保护健康:富裕国家必须做得更多,做得更快。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-09-01 Epub Date: 2021-10-15
Lukoye Atwoli, Abdullah H Baqui, Thomas Benfield, Raffaella Bosurgi, Fiona Godlee, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Carlos Augusto Monteiro, Ian Norman, Kirsten Patrick, Nigel Praities, Marcel Gm Olde Rikkert, Eric J Rubin, Peush Sahni, Richard Smith, Nicholas J Talley, Sue Turale, Damián Vázquez
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引用次数: 0
Author Self-Citation in the Turkish Otorhinolaryngology Literature. 土耳其耳鼻喉科文献中的作者自我引证。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-09-01 Epub Date: 2021-10-15 DOI: 10.4274/tao.2021.2021-5-16
Ali Bayram

Objective: To evaluate the prevalence and other characteristics of author self-citations in six Turkey-originated general otorhinolaryngology (ORL) journals of Turkish ORL literature.

Methods: A total of 970 articles published in six Turkey-originated general ORL journals (ENT Updates, Journal of Ear Nose Throat and Head Neck Surgery, KBB-Forum, Praxis of Otorhinolaryngology, The Turkish Journal of Ear Nose and Throat, and Turkish Archives of Otorhinolaryngology) in 2016-2020 were analyzed for author self-citations. The association between author self-citations and journal types, study types, study topics, country of origin, and compatibility with the topic were also evaluated.

Results: There were 265 author self-citations (0.273 per article) which corresponded to 1.36% of all citations. There was no significant difference between the journal types, study topics, and origin of the studies in terms of mean self-citation values per study, whereas case reports had significantly lower self-citations than review and original investigations. There were three citations (1.1%) that were irrelevant to the study topic.

Conclusion: To the best of our knowledge, this is the first study that investigated the practice of author self-citation in Turkish ORL literature. Author self-citation rate in the Turkish-originated general ORL journals was found remarkably lower than the medical literature, whereas the self-citations were found compatible with the study topic to a very large extent. Members of the scientific community including authors, readers, and journal editors should be cautious regarding the unethical practices of self-citations.

目的:评价6种土耳其普通耳鼻喉科(general otorhinolaryngology, ORL)期刊土耳其ORL文献的作者自引率及其特点。方法:对2016-2020年发表在6种土耳其源性ORL期刊(ENT Updates、Journal of Ear Nose咽喉and Head Neck Surgery、kbr - forum、Praxis of Otorhinolaryngology、The Turkish Journal of Ear Nose and Throat、Turkish Archives of otorhinolyngology)上的970篇文章进行作者自引分析。作者自引与期刊类型、研究类型、研究主题、原产国以及与主题的兼容性之间的关系也被评估。结果:作者自引用265篇(0.273篇/篇),占总被引数的1.36%。每份研究的平均自引值在期刊类型、研究主题和研究来源之间没有显著差异,而病例报告的自引率明显低于综述和原始调查。有3次引用(1.1%)与研究主题无关。结论:据我们所知,这是第一个调查土耳其ORL文献中作者自引实践的研究。土耳其文普通ORL期刊的作者自引率明显低于医学文献,而自引与研究主题有很大程度的契合。包括作者、读者和期刊编辑在内的科学界成员应该警惕自我引用的不道德行为。
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引用次数: 0
The Importance of Prostate-Specific Membrane Antigen Expression in Carotid Body Paragangliomas. 前列腺特异性膜抗原在颈动脉体副神经节瘤中的意义。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-09-01 Epub Date: 2021-10-15 DOI: 10.4274/tao.2021.2021-3-17
Hasan Yasan, Yusuf Çağdaş Kumbul, İbrahim Metin Çiriş, Mehmet Emre Sivrice, Erdoğan Okur

Objective: Prostate-specific membrane antigen (PSMA) is a transmembrane protein expressed in prostate cancer. It is, however, also expressed in the neovasculature of some non-prostatic solid tumors. Carotid body paragangliomas (CBPs) are highly vascular neoplasms. In this study, we aimed to investigate the possible role of PSMA expression in CBPs. There are no studies in the literature that report to have investigated the relationship between PSMA and CBPs.

Methods: This study is a retrospective analysis of cases diagnosed with CBP based on their demographic, clinical, radiological, surgical and immunohistochemical findings. Immunohistochemical examination results of Ki-67, S100, synaptophysin, chromogranin were retrieved from patient files. Then, the paraffin blocks of CBPs specimens, stained by PSMA-antibody by immunohistochemical methods were examined histopathologically.

Results: The number of patients operated on for CBP was 12 (four men and eight women). Ten out of 12 specimens were suitable for staining and histopathological examination. Capsular and/or vascular invasions of tumors were seen in complicated cases. Intratumoral vascular PSMA expression was seen in all specimens except one. Extratumoral vascular PSMA expression was not detected in any of the cases. Tumoral cell PSMA staining was seen in six of ten cases.

Conclusion: We found higher intratumoral vascular expressions of PSMA nearly in all CBPs, but we could not assess the statistical significance because of the small number of specimens. These data might be a guide for future studies that are planned for either diagnostic or therapeutic approaches to CBPs.

目的:前列腺特异性膜抗原(PSMA)是一种在前列腺癌中表达的跨膜蛋白。然而,它也在一些非前列腺实体瘤的新生血管中表达。颈动脉体副神经节瘤(CBPs)是高度血管性肿瘤。在这项研究中,我们旨在探讨PSMA表达在CBPs中的可能作用。文献中没有研究报告调查了PSMA和CBPs之间的关系。方法:本研究回顾性分析基于人口学、临床、放射学、手术和免疫组织化学结果诊断为CBP的病例。从患者档案中检索Ki-67、S100、synaptophysin、chromogranin的免疫组化检查结果。免疫组化法对CBPs标本石蜡块进行psma抗体染色,进行组织病理学检查。结果:手术治疗CBP患者12例(男4例,女8例)。12个标本中有10个适合染色和组织病理学检查。肿瘤包膜和/或血管浸润见于复杂病例。除1例外,其余标本均可见瘤内血管PSMA表达。在所有病例中均未检测到瘤外血管PSMA表达。10例中有6例可见肿瘤细胞PSMA染色。结论:PSMA在几乎所有CBPs中均有较高的肿瘤内血管表达,但由于样本数量少,我们无法评估其统计学意义。这些数据可能为未来的CBPs诊断或治疗方法研究提供指导。
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引用次数: 0
An Incidental Chorda Tympani Schwannoma Identified During Middle Ear Surgery. 中耳手术中偶然发现的鼓室索神经鞘瘤。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-09-01 Epub Date: 2021-10-15 DOI: 10.4274/tao.2021-5-2
Kasım Durmuş, Murat Öztürk, Büşra Yaprak Bayrak, Çiğdem Vural

Chorda tympani schwannomas are rare benign tumors of the middle ear cleft. This is a case of incidental chorda tympani schwannoma identified intraoperatively. The patient was a 50-year-old male with chronic active otitis media complicated by left-sided facial paralysis. During closed mastoidectomy and tympanoplasty approach, a well-demarcated swelling on the left chorda tympani nerve was identified and sectioned for pathologic evaluation. The histopathologic evaluation established the diagnosis of schwannoma. Although the tumor was unlikely the cause of the disease process in this patient, his facial paralysis and middle ear disease were resolved after surgery.

摘要鼓室索神经鞘瘤是一种少见的中耳裂良性肿瘤。这是一例术中发现的偶发性鼓室索神经鞘瘤。患者为50岁男性,慢性活动性中耳炎合并左侧面瘫。在闭合性乳突切除术和鼓室成形术中,发现左侧鼓室索神经上有一个界限清晰的肿胀,并进行了病理评估。组织病理学检查确定了神经鞘瘤的诊断。虽然肿瘤不太可能是该患者发病过程的原因,但他的面瘫和中耳疾病在手术后得到了解决。
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引用次数: 0
Where is my ear? - Cervical Chondrocutaneous Branchial Remnant. 我的耳朵在哪里?-颈椎软骨皮鳃裂残余。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-09-01 Epub Date: 2021-10-15 DOI: 10.4274/tao.2021.2021-6-13
Smile Kajal, Anam Ahmed, Anurag Gupta
A 6-year-old boy presented with the absence of pinna on the left side since birth. A cutaneous appendage emerging from the neck on the left side was discovered during the examination (Figure 1). Deep palpation revealed a firm texture like cartilage. On the left side, a primitive firm cartilage was palpated in the helix region (Figure 2). The rest of the cartilaginous framework and external auditory canal (EAC) opening was absent on the left side. On the right side, the pinna was smaller in size and loped. High resolution computed tomography (HRCT) of temporal bone showed an atretic and stenosed EAC on the left and ride side, respectively. Ossicular lump was noted on both sides on HRCT, but all inner ear structures appeared normal in both ears. Pure tone audiometry revealed moderate and mild conductive hearing loss on the left and right sides, respectively. Magnetic resonance imaging of the neck was done to rule out any branchial abnormality. It did not reveal any cyst/sinus/fistula. A provisional diagnosis of cervical chondrocutaneous branchial remnant (CCBR) with leftsided microtia and EAC atresia was made on clinico-radiological basis. After a thorough discussion with the father, the patient was planned for the excision of the cervical mass and staged pinnaplasty and canaloplasty on the left side at a later stage. Histopathological examination after excision showed elastic cartilage rests covered by normal skin consisting of epidermis, dermis, adnexal structures, and subcutaneous fat compatible with CCBR.
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引用次数: 2
期刊
Turkish Archives of Otorhinolaryngology
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