Ultrasonics Sonochemistry最新文献_第10页

Impact of ultrasound-assisted single washing process on tilapia mince: Biochemical changes, structural modifications, and gel formation 超声辅助单次洗涤过程对罗非鱼肉糜的影响：生化变化、结构修饰和凝胶形成

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-12-14 DOI: 10.1016/j.ultsonch.2025.107707

Ali Hamzeh , Lobdaw Saelee , Kanjana Thumanu , Jae W. Park , Jirawat Yongsawatdigul

Ultrasound (US)-assisted single washing was applied to reduce water usage in tilapia mince washing during surimi production. The mince-to-water ratio of 1:2 in US-assisted washing was compared with ratios of 1:2 and 1:3 in conventional washing (CW−2 and CW−3, respectively). Screening of US power revealed the greatest effect at an intensity of 3.19 W/cm² on mince whiteness (p < 0.05), without damage to protein polypeptide chains, and no extensive biochemical changes. Subsequently, the mince was subjected to various US exposure times of 1, 3, and 5 min (US−1, US−3, and US−5, respectively) at 3.19 W/cm², maintaining the same total washing time of 10 min across all treatments. US-assisted washing increased myofibrillar protein loss compared with that with CW, as indicated by sodium dodecyl sulfate–polyacrylamide gel electrophoresis, and the loss increased with longer exposure time—from 7.57 % in US−1 to 12.76 % in US−5. The US−1-washed mince exhibited the highest Ca²⁺–ATPase activity and reactive sulfhydryl (SH) content, even higher than that of CW−3 (p < 0.05). Random coil structures decreased in US−5, while other secondary structures did not change significantly. Tertiary structure analysis using Raman spectroscopy revealed comparable tyrosine and tryptophan exposure in US−1, US−3, and CW−3, which may contribute to the increased breaking force and distance through higher extent of hydrophobic interactions in their corresponding surimi gels compared with CW−2 and US − 5 (p < 0.05). Oxidation of SH groups and hydrophobic interactions increased in US−3 and US−5 (p < 0.05). US−1 was identified as the optimal condition for a single washing of tilapia mince to reduce water usage with minimal negative effects on protein.

为了减少罗非鱼糜在鱼糜生产过程中的洗涤用水量，采用超声辅助单次洗涤。将us辅助洗涤中1:2的肉水比与1:2和1:3的常规洗涤（分别为CW−2和CW−3）进行比较。US功率筛选结果显示，3.19 W/cm2强度对肉糜白度影响最大（p <； 0.05），对蛋白多肽链无损伤，且无广泛的生化变化。随后，将肉糜以3.19 W/cm2的速度进行1、3和5 min（分别为US - 1、US - 3和US - 5）的不同US暴露时间，在所有处理中保持相同的10 min的总洗涤时间。十二烷基硫酸钠-聚丙烯酰胺凝胶电泳显示，与连续洗涤相比，超声辅助洗涤增加了肌原纤维蛋白的损失，并且随着暴露时间的延长，损失从US−1的7.57 %增加到US−5的12.76 %。US−1水洗肉糜Ca2+ - atp酶活性和活性巯基（SH）含量最高，甚至高于CW−3水洗肉糜（p <； 0.05）。随机线圈结构在US−5中减少，而其他二级结构没有明显变化。利用拉曼光谱进行三级结构分析，发现US−1、US−3和CW−3中酪氨酸和色氨酸的暴露程度相当，与CW−2和US − 5相比，这可能有助于通过在相应的鱼糜凝胶中更高程度的疏水相互作用来增加断裂力和距离（p <； 0.05）。在US - 3和US - 5中，SH基团的氧化和疏水相互作用增加（p <； 0.05）。US - 1被确定为罗非鱼肉末单次洗涤的最佳条件，以减少水的使用，对蛋白质的负面影响最小。

{"title":"Impact of ultrasound-assisted single washing process on tilapia mince: Biochemical changes, structural modifications, and gel formation","authors":"Ali Hamzeh , Lobdaw Saelee , Kanjana Thumanu , Jae W. Park , Jirawat Yongsawatdigul","doi":"10.1016/j.ultsonch.2025.107707","DOIUrl":"10.1016/j.ultsonch.2025.107707","url":null,"abstract":"<div><div>Ultrasound (US)-assisted single washing was applied to reduce water usage in tilapia mince washing during surimi production. The mince-to-water ratio of 1:2 in US-assisted washing was compared with ratios of 1:2 and 1:3 in conventional washing (CW−2 and CW−3, respectively). Screening of US power revealed the greatest effect at an intensity of 3.19 W/cm<sup>2</sup> on mince whiteness (<em>p</em> < 0.05), without damage to protein polypeptide chains, and no extensive biochemical changes. Subsequently, the mince was subjected to various US exposure times of 1, 3, and 5 min (US−1, US−3, and US−5, respectively) at 3.19 W/cm<sup>2</sup>, maintaining the same total washing time of 10 min across all treatments. US-assisted washing increased myofibrillar protein loss compared with that with CW, as indicated by sodium dodecyl sulfate–polyacrylamide gel electrophoresis, and the loss increased with longer exposure time—from 7.57 % in US−1 to 12.76 % in US−5. The US−1-washed mince exhibited the highest Ca<sup>2+</sup>–ATPase activity and reactive sulfhydryl (SH) content, even higher than that of CW−3 (<em>p</em> < 0.05). Random coil structures decreased in US−5, while other secondary structures did not change significantly. Tertiary structure analysis using Raman spectroscopy revealed comparable tyrosine and tryptophan exposure in US−1, US−3, and CW−3, which may contribute to the increased breaking force and distance through higher extent of hydrophobic interactions in their corresponding surimi gels compared with CW−2 and US − 5 (<em>p</em> < 0.05). Oxidation of SH groups and hydrophobic interactions increased in US−3 and US−5 (<em>p</em> < 0.05). US−1 was identified as the optimal condition for a single washing of tilapia mince to reduce water usage with minimal negative effects on protein.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"124 ","pages":"Article 107707"},"PeriodicalIF":9.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145753366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving amino acids and digestive peptides contents of chicken breast paste using ultrasound-assisted EGCG treatment within a complex meat matrix 超声辅助EGCG处理复合肉基质提高鸡胸肉膏氨基酸和消化肽含量

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-12-17 DOI: 10.1016/j.ultsonch.2025.107728

Jiahui Chen , Xinglian Xu

This study systematically investigated the unique effects of ultrasound-assisted EGCG treatment on the amino acids and digestive peptides contents of chicken breast paste. As a complex system, chicken samples exhibited distinct ultrasonic responses that cannot be extrapolated from simplified protein-based studies. To be specific, results demonstrated that ultrasound-assisted EGCG treatment significantly enhanced the essential/non-essential amino acids ratio to 41.03%, which could not be acquired through individual treatment. More so, structural analysis of meat pastes revealed that particle size was reduced by 62.72% after treatment. Furthermore, ultrasound-assisted EGCG treatment reduced total water contents by 13.65%, thereby promoting the transition of immobilized to free water. The above-mentioned changes enhanced enzymatic accessibility and increased peptide contents by 2.18%. This study innovatively highlighted the efficiency of ultrasonic-assisted EGCG treatment in enhancing nutritional features at the level of chicken matrix, offering an important advancement from theory to practice.

本研究系统研究了超声辅助EGCG处理对鸡胸酱氨基酸和消化肽含量的独特影响。作为一个复杂的系统，鸡样品表现出不同的超声反应，不能从简化的蛋白质为基础的研究推断。结果表明，超声辅助EGCG处理显著提高了必需/非必需氨基酸比例，达到41.03%，这是单独处理无法获得的。更重要的是，对肉酱的结构分析表明，处理后的颗粒大小减少了62.72%。超声辅助EGCG处理使总含水量降低了13.65%，促进了固定水向游离水的转变。上述变化提高了酶的可及性，使肽含量提高了2.18%。本研究创新性地强调了超声辅助EGCG处理在鸡基质水平上提高营养特性的有效性，从理论到实践都有重要的进展。

{"title":"Improving amino acids and digestive peptides contents of chicken breast paste using ultrasound-assisted EGCG treatment within a complex meat matrix","authors":"Jiahui Chen , Xinglian Xu","doi":"10.1016/j.ultsonch.2025.107728","DOIUrl":"10.1016/j.ultsonch.2025.107728","url":null,"abstract":"<div><div>This study systematically investigated the unique effects of ultrasound-assisted EGCG treatment on the amino acids and digestive peptides contents of chicken breast paste. As a complex system, chicken samples exhibited distinct ultrasonic responses that cannot be extrapolated from simplified protein-based studies. To be specific, results demonstrated that ultrasound-assisted EGCG treatment significantly enhanced the essential/non-essential amino acids ratio to 41.03%, which could not be acquired through individual treatment. More so, structural analysis of meat pastes revealed that particle size was reduced by 62.72% after treatment. Furthermore, ultrasound-assisted EGCG treatment reduced total water contents by 13.65%, thereby promoting the transition of immobilized to free water. The above-mentioned changes enhanced enzymatic accessibility and increased peptide contents by 2.18%. This study innovatively highlighted the efficiency of ultrasonic-assisted EGCG treatment in enhancing nutritional features at the level of chicken matrix, offering an important advancement from theory to practice.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"124 ","pages":"Article 107728"},"PeriodicalIF":9.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145785407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in ultrasound-enhanced recovery of marine algal polysaccharides: toward sustainable bioprocessing 海洋藻类多糖超声强化回收的研究进展：迈向可持续生物处理

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2025-12-01 Epub Date: 2025-11-16 DOI: 10.1016/j.ultsonch.2025.107683

Tehmina Naseem , Khushi Ali , Nisha Zahid , Syed Ali Hassan , Gholamreza Abdi , Seydi Yıkmış , Rana Muhammad Aadil

The growing emphasis on environmental sustainability has intensified interest in the extraction and valorization of polysaccharides from marine algal species due to their non-toxic nature and notable bioactivities. Although various conventional extraction techniques have been employed, these often involve high energy consumption, prolonged processing times, limited selectivity, and the potential degradation of polysaccharide bioactivity. To address these limitations, a range of sustainable and cost-effective extraction methods has been developed, including enzyme-assisted extraction (EAE), supercritical fluid extraction (SFE), subcritical water extraction (SWE), microwave-assisted extraction (MAE), and ultrasound-assisted extraction (UAE). Among these, the UAE, either as a standalone method or integrated within a biorefinery framework, has emerged as a promising and green technology. It offers higher extraction efficiency with reduced time, energy, and cost requirements. Polysaccharides extracted via ultrasound (US) have demonstrated enhanced anticancer, bioactive, and rheological properties. Furthermore, integrating the UAE with green solvents, such as natural deep eutectic solvents (NaDESs), or complementary techniques, including MAE, hot water extraction (HWE), and EAE, has been shown to further improve yields by 2–6 % and enhance functional quality. This review highlights the potential of the UAE, both individually and in combination with other methods for the efficient recovery of algal polysaccharides. It also evaluates the influence of the UAE on the biofunctional properties of the extracted compounds, underscoring their applicability across diverse industrial sectors. Nonetheless, further research is warranted to optimize process parameters, ensure safety, enhance antioxidant activity (AOA), and improve purification and characterization, as well as better understand the structure–activity relationships of these valuable biopolymers.

随着对环境可持续性的日益重视，人们对从海洋藻类中提取和增值多糖的兴趣日益浓厚，因为它们具有无毒的性质和显著的生物活性。尽管采用了各种传统的提取技术，但这些技术通常涉及高能耗、长时间的处理、有限的选择性和多糖生物活性的潜在降解。为了解决这些限制，人们开发了一系列可持续且具有成本效益的提取方法，包括酶辅助提取（EAE）、超临界流体提取（SFE）、亚临界水提取（SWE）、微波辅助提取（MAE）和超声辅助提取（UAE）。其中，无论是作为一种独立的方法，还是与生物炼制框架相结合，阿联酋都已成为一种有前途的绿色技术。它提供了更高的萃取效率，减少了时间、能源和成本要求。通过超声波提取的多糖（US）已经证明了增强的抗癌、生物活性和流变学特性。此外，将UAE与绿色溶剂（如天然深共晶溶剂（NaDESs））或互补技术（包括MAE、热水萃取（HWE）和EAE）相结合，已被证明可进一步提高产率2-6%，并提高功能质量。这篇综述强调了阿联酋的潜力，无论是单独还是与其他方法相结合，有效地回收藻类多糖。它还评估了阿联酋对提取化合物的生物功能特性的影响，强调了它们在不同工业部门的适用性。尽管如此，需要进一步的研究来优化工艺参数，确保安全性，提高抗氧化活性（AOA），改进纯化和表征，以及更好地了解这些有价值的生物聚合物的结构-活性关系。

{"title":"Advances in ultrasound-enhanced recovery of marine algal polysaccharides: toward sustainable bioprocessing","authors":"Tehmina Naseem , Khushi Ali , Nisha Zahid , Syed Ali Hassan , Gholamreza Abdi , Seydi Yıkmış , Rana Muhammad Aadil","doi":"10.1016/j.ultsonch.2025.107683","DOIUrl":"10.1016/j.ultsonch.2025.107683","url":null,"abstract":"<div><div>The growing emphasis on environmental sustainability has intensified interest in the extraction and valorization of polysaccharides from marine algal species due to their non-toxic nature and notable bioactivities. Although various conventional extraction techniques have been employed, these often involve high energy consumption, prolonged processing times, limited selectivity, and the potential degradation of polysaccharide bioactivity. To address these limitations, a range of sustainable and cost-effective extraction methods has been developed, including enzyme-assisted extraction (EAE), supercritical fluid extraction (SFE), subcritical water extraction (SWE), microwave-assisted extraction (MAE), and ultrasound-assisted extraction (UAE). Among these, the UAE, either as a standalone method or integrated within a biorefinery framework, has emerged as a promising and green technology. It offers higher extraction efficiency with reduced time, energy, and cost requirements. Polysaccharides extracted via ultrasound (US) have demonstrated enhanced anticancer, bioactive, and rheological properties. Furthermore, integrating the UAE with green solvents, such as natural deep eutectic solvents (NaDESs), or complementary techniques, including MAE, hot water extraction (HWE), and EAE, has been shown to further improve yields by 2–6 % and enhance functional quality. This review highlights the potential of the UAE, both individually and in combination with other methods for the efficient recovery of algal polysaccharides. It also evaluates the influence of the UAE on the biofunctional properties of the extracted compounds, underscoring their applicability across diverse industrial sectors. Nonetheless, further research is warranted to optimize process parameters, ensure safety, enhance antioxidant activity (AOA), and improve purification and characterization, as well as better understand the structure–activity relationships of these valuable biopolymers.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"123 ","pages":"Article 107683"},"PeriodicalIF":9.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145531119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Next-generation suturing: Moisture-pressurized and ultrasonic synthesis of Cu–Ag–Al nanorods for antibacterial dental and dialysis applications 新一代缝合：用于抗菌牙科和透析应用的Cu-Ag-Al纳米棒的湿加压和超声波合成

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2025-12-01 Epub Date: 2025-11-08 DOI: 10.1016/j.ultsonch.2025.107672

Wenhao Tao , Yibo Wei , Zhizen Quan, Chen Li, Gang Tian , Xiaogang Xu

Cu–Ag–Al trimetallic nanorods were synthesized using a moisture-pressurized ultrasonic method and evaluated as antibacterial coatings for dental and dialysis sutures. The nanorods exhibited a mesoporous structure (surface area = 28.6 m² g⁻¹) and strong crystalline stability confirmed by XRD, FESEM, BET, TGA, and Raman analyses. The coated sutures showed concentration-dependent antibacterial and antibiofilm activity, achieving up to 86.5 % inhibition against E. coli and 74.2 % against S. aureus, with durable adhesion after washing. Cytotoxicity assays on KB and U87 cells revealed selective anticancer potential and acceptable biocompatibility at low doses. The developed ultrasonic synthesis offers a rapid, energy-efficient, and scalable route compared with conventional hydrothermal and microwave methods. The coatings maintained high stability, reduced the risk of nanoparticle release, and exhibited environmental and clinical safety potential. The enhanced antibacterial effect is attributed to synergistic reactive oxygen species (ROS) generation and membrane disruption arising from the Cu–Ag–Al interaction. This scalable, low-cost approach demonstrates promise for next-generation infection-resistant sutures in clinical dentistry and dialysis applications.

采用湿压超声法合成了Cu-Ag-Al三金属纳米棒，并对其作为牙科和透析缝合线的抗菌涂层进行了评价。通过XRD、FESEM、BET、TGA和Raman分析证实，纳米棒具有介孔结构（表面积为28.6 m2 g−1）和较强的晶体稳定性。包被缝线显示出浓度依赖性的抗菌和抗生物膜活性，对大肠杆菌的抑制率高达86.5%，对金黄色葡萄球菌的抑制率高达74.2%，洗涤后具有持久的粘附性。KB和U87细胞的细胞毒性实验显示，在低剂量下，KB和U87细胞具有选择性的抗癌潜力和良好的生物相容性。与传统的水热法和微波法相比，所开发的超声合成方法具有快速、节能和可扩展的特点。该涂层保持了高稳定性，降低了纳米颗粒释放的风险，并显示出环境和临床安全潜力。增强的抗菌效果归因于协同活性氧（ROS）的产生和Cu-Ag-Al相互作用引起的膜破坏。这种可扩展的、低成本的方法在临床牙科和透析应用中展示了下一代抗感染缝合线的前景。

{"title":"Next-generation suturing: Moisture-pressurized and ultrasonic synthesis of Cu–Ag–Al nanorods for antibacterial dental and dialysis applications","authors":"Wenhao Tao , Yibo Wei , Zhizen Quan, Chen Li, Gang Tian , Xiaogang Xu","doi":"10.1016/j.ultsonch.2025.107672","DOIUrl":"10.1016/j.ultsonch.2025.107672","url":null,"abstract":"<div><div>Cu–Ag–Al trimetallic nanorods were synthesized using a moisture-pressurized ultrasonic method and evaluated as antibacterial coatings for dental and dialysis sutures. The nanorods exhibited a mesoporous structure (surface area = 28.6 m<sup>2</sup> g<sup>−1</sup>) and strong crystalline stability confirmed by XRD, FESEM, BET, TGA, and Raman analyses. The coated sutures showed concentration-dependent antibacterial and antibiofilm activity, achieving up to 86.5 % inhibition against <em>E. coli</em> and 74.2 % against <em>S. aureus</em>, with durable adhesion after washing. Cytotoxicity assays on KB and U87 cells revealed selective anticancer potential and acceptable biocompatibility at low doses. The developed ultrasonic synthesis offers a rapid, energy-efficient, and scalable route compared with conventional hydrothermal and microwave methods. The coatings maintained high stability, reduced the risk of nanoparticle release, and exhibited environmental and clinical safety potential. The enhanced antibacterial effect is attributed to synergistic reactive oxygen species (ROS) generation and membrane disruption arising from the Cu–Ag–Al interaction. This scalable, low-cost approach demonstrates promise for next-generation infection-resistant sutures in clinical dentistry and dialysis applications.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"123 ","pages":"Article 107672"},"PeriodicalIF":9.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145462168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CFD-PBM modelling for predicting the size and distribution of silica nanoparticles synthesized in an ultrasound-assisted swirling vortex flow reactor CFD-PBM模型预测超声辅助旋流反应器中合成的二氧化硅纳米颗粒的尺寸和分布

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2025-12-01 Epub Date: 2025-11-01 DOI: 10.1016/j.ultsonch.2025.107663

Lu Liu , Weibin Shi , Bin Li , Guichao Wang , Yanqing Guo , Xiaogang Yang , Weibiao Zhou

A coupled computational fluid dynamics-population balance model (CFD-PBM) framework is developed and experimentally validated to predict the size and distribution of silica nanoparticles in an ultrasound-assisted swirling vortex flow reactor (SVFR). Two key aggregation parameters (i.e., bridge strength parameter A_p, and the initial particle number coefficient C₁) are identified and corrected against experimental data, enabling accurate prediction of primary and secondary peaks in the particle size distribution. The modelling results show that increasing vortex Reynolds number promotes particle collisions, leading to a high frequency of particle collisions and thus relatively large particle sizes, while ultrasound exerts a dual effect by enhancing collisions and simultaneously suppressing excessive aggregation via turbulence-induced shear. These findings highlight the critical role of ultrasound-assisted turbulence in controlling nanoparticle formation, providing insights for reactor design and scale-up.

建立了一种计算流体动力学-种群平衡模型（CFD-PBM）框架，并通过实验验证了该框架可用于预测超声辅助旋流反应器（SVFR）中二氧化硅纳米颗粒的尺寸和分布。识别出两个关键聚集参数（即桥梁强度参数Ap和初始颗粒数系数C1），并根据实验数据进行校正，从而准确预测粒径分布的主峰和次峰。模拟结果表明，涡流雷诺数的增加促进了颗粒碰撞，导致颗粒碰撞频率高，颗粒尺寸较大，而超声在增强碰撞的同时，通过湍流诱导剪切抑制过度聚集，起到双重作用。这些发现强调了超声辅助湍流在控制纳米颗粒形成中的关键作用，为反应器的设计和放大提供了见解。

{"title":"CFD-PBM modelling for predicting the size and distribution of silica nanoparticles synthesized in an ultrasound-assisted swirling vortex flow reactor","authors":"Lu Liu , Weibin Shi , Bin Li , Guichao Wang , Yanqing Guo , Xiaogang Yang , Weibiao Zhou","doi":"10.1016/j.ultsonch.2025.107663","DOIUrl":"10.1016/j.ultsonch.2025.107663","url":null,"abstract":"<div><div>A coupled computational fluid dynamics-population balance model (CFD-PBM) framework is developed and experimentally validated to predict the size and distribution of silica nanoparticles in an ultrasound-assisted swirling vortex flow reactor (SVFR). Two key aggregation parameters (i.e., bridge strength parameter <em>A<sub>p</sub></em>, and the initial particle number coefficient <em>C</em><sub>1</sub>) are identified and corrected against experimental data, enabling accurate prediction of primary and secondary peaks in the particle size distribution. The modelling results show that increasing vortex Reynolds number promotes particle collisions, leading to a high frequency of particle collisions and thus relatively large particle sizes, while ultrasound exerts a dual effect by enhancing collisions and simultaneously suppressing excessive aggregation via turbulence-induced shear. These findings highlight the critical role of ultrasound-assisted turbulence in controlling nanoparticle formation, providing insights for reactor design and scale-up.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"123 ","pages":"Article 107663"},"PeriodicalIF":9.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound-assisted extraction enhances recovery of antioxidant-rich carbohydrate fraction from mixed microalgae species 超声辅助提取提高了混合微藻中富含抗氧化剂的碳水化合物组分的回收率

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2025-12-01 Epub Date: 2025-10-30 DOI: 10.1016/j.ultsonch.2025.107656

Eldwin Ze Hao Ooi , Eng-Seng Chan , Cher Pin Song , Janarthanan Pushpamalar , Yee-Ying Lee

The effects of ultrasonic processing parameters on the functional and physicochemical properties of microalgae carbohydrates remain poorly understood, despite evidence from plant-based extractions showing that sonication conditions strongly influence bioactive compound yield and antioxidant activity from carbohydrates. This study investigated the effects of ultrasonic-assisted extraction (UAE) parameters on the yield, composition, and antioxidant activity of carbohydrates extracted from defatted mixed microalgae biomass. A single-factor approach was employed to test different extraction times (10–30 min), amplitudes (20–100 %), and solid-to-solvent ratios (1:10–1:30 g/mL). All analyses were conducted in triplicate, and statistical significance was determined at p < 0.05. Results showed that processing time was the most influential factor in improving antioxidant activity. Under optimal UAE conditions (25 min, 100 % amplitude, 1:15 g/mL), the extract contained significantly higher uronic acid, sulphate, and fibre contents (p < 0.05) compared to hot water extraction. These changes corresponded to stronger antioxidant activity (∼35 % increase in DPPH radical scavenging). Correlation analysis further revealed that uronic acid had the strongest positive influence on antioxidant activity. In conclusion, UAE improved both the yield and antioxidant properties of microalgae carbohydrates compared with hot water extraction. With its high fibre content and bioactivity, the extract may have potential applications as a functional food ingredient.

超声波处理参数对微藻碳水化合物的功能和理化性质的影响尚不清楚，尽管基于植物的提取证据表明，超声波处理条件对碳水化合物的生物活性化合物产量和抗氧化活性有很大影响。研究了超声辅助提取工艺对脱脂混合微藻生物量碳水化合物提取率、组成及抗氧化活性的影响。采用单因素法考察不同提取时间（10-30 min）、提取幅度（20 - 100%）和料液比（1:10-1:30 g/mL）。所有分析均为三份，p <； 0.05为差异有统计学意义。结果表明，加工时间是影响其抗氧化活性的主要因素。在最佳UAE条件下（25分钟，100%振幅，1:15 g/mL），与热水提取相比，提取物含有显著更高的尿酸，硫酸盐和纤维含量（p < 0.05）。这些变化对应于更强的抗氧化活性（DPPH自由基清除能力增加~ 35%）。相关分析进一步表明，糖醛酸对抗氧化活性的正向影响最大。综上所述，与热水提取相比，UAE提高了微藻碳水化合物的产率和抗氧化性能。由于其高纤维含量和生物活性，其提取物作为功能性食品成分可能具有潜在的应用前景。

{"title":"Ultrasound-assisted extraction enhances recovery of antioxidant-rich carbohydrate fraction from mixed microalgae species","authors":"Eldwin Ze Hao Ooi , Eng-Seng Chan , Cher Pin Song , Janarthanan Pushpamalar , Yee-Ying Lee","doi":"10.1016/j.ultsonch.2025.107656","DOIUrl":"10.1016/j.ultsonch.2025.107656","url":null,"abstract":"<div><div>The effects of ultrasonic processing parameters on the functional and physicochemical properties of microalgae carbohydrates remain poorly understood, despite evidence from plant-based extractions showing that sonication conditions strongly influence bioactive compound yield and antioxidant activity from carbohydrates. This study investigated the effects of ultrasonic-assisted extraction (UAE) parameters on the yield, composition, and antioxidant activity of carbohydrates extracted from defatted mixed microalgae biomass. A single-factor approach was employed to test different extraction times (10–30 min), amplitudes (20–100 %), and solid-to-solvent ratios (1:10–1:30 g/mL). All analyses were conducted in triplicate, and statistical significance was determined at p < 0.05. Results showed that processing time was the most influential factor in improving antioxidant activity. Under optimal UAE conditions (25 min, 100 % amplitude, 1:15 g/mL), the extract contained significantly higher uronic acid, sulphate, and fibre contents (p < 0.05) compared to hot water extraction. These changes corresponded to stronger antioxidant activity (∼35 % increase in DPPH radical scavenging). Correlation analysis further revealed that uronic acid had the strongest positive influence on antioxidant activity. In conclusion, UAE improved both the yield and antioxidant properties of microalgae carbohydrates compared with hot water extraction. With its high fibre content and bioactivity, the extract may have potential applications as a functional food ingredient.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"123 ","pages":"Article 107656"},"PeriodicalIF":9.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145383589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound-assisted hot water extraction of yellow leaves of Pu’er tea polysaccharides: Extraction process, characterization, antioxidant and hypoglycemic activity 超声辅助热水提取普洱茶黄叶多糖：提取工艺、表征及抗氧化降糖活性

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2025-12-01 Epub Date: 2025-10-27 DOI: 10.1016/j.ultsonch.2025.107653

Ao Zhao , Lina Sun , Fu Xu, Wendie Gan, Biaoying Guo, Lianzhou Jiang, Xia Wu

Yellow leaves of Pu’er tea are classified as lower-grade Pu’er tea, and polysaccharides being its principal active components. Pu’er tea polysaccharides (PTPS) were optimally extracted from yellow leaves of Pu’er tea using ultrasound-assisted hot water extraction with the following parameters: solid-to-liquid ratio of 1:25 (w/v), ultrasonic temperature of 70 °C, ultrasonic power of 500 W, and ultrasonic time of 40 min. Two fractions, PTPS-4A and PTPS-5A, were clearly isolated and purified. Their antioxidant and hypoglycemic effects were compared in a lab after examining their structural features. PTPS-4A and PTPS-5A were mostly composed of fucose, rhamnose, arabinose, galactose, glucose, mannose, and glucuronic acid. They manifested as flexible chains and assumed a linear spline curve suggestive of an earthworm-like conformation. The nuclear magnetic resonance investigation found α- and β-glycosidic linkages (δ4.30–5.95 ppm and δ4.29–4.97 ppm, respectively) in PTPS-4A and PTPS-5A. PTPS-4A had enhanced DPPH and hydroxyl radical removal, with IC₅₀ values of 1.79 ± 0.07 mg/mL and 6.42 ± 0.16 mg/mL, respectively. The intermediate concentration value of 5.22 ± 0.08 mg/mL of PTPS-4A indicated a stronger inhibitory impact on α-glucosidase. PTPS-4A and PTPS-5A did not affect α-amylase in any way. The PTPS-4A fraction from this study may be further processed to create polysaccharide-based hypoglycemic and antioxidant products.

普洱茶黄叶属低档普洱茶，其主要活性成分为多糖。采用超声辅助热水提取普洱茶黄叶多糖的最佳工艺参数为：料液比1:25 (w/v)，超声温度70 °C，超声功率500 w，超声时间40 min。明确分离纯化了PTPS-4A和PTPS-5A两个组分。在检测了它们的结构特征后，在实验室中比较了它们的抗氧化和降糖作用。PTPS-4A和PTPS-5A主要由焦糖、鼠李糖、阿拉伯糖、半乳糖、葡萄糖、甘露糖和葡萄糖醛酸组成。它们表现为柔性链，呈线性样条曲线，具有蚯蚓状构象。核磁共振发现PTPS-4A和PTPS-5A中存在α-和β-糖苷键（分别为δ4.30-5.95 ppm和δ4.29-4.97 ppm）。PTPS-4A具有增强DPPH和羟基自由基清除的作用，IC50值分别为1.79 ± 0.07 mg/mL和6.42 ± 0.16 mg/mL。PTPS-4A的中间浓度为5.22 ± 0.08 mg/mL，对α-葡萄糖苷酶有较强的抑制作用。PTPS-4A和PTPS-5A对α-淀粉酶无明显影响。本研究的PTPS-4A馏分可以进一步加工成以多糖为基础的降糖和抗氧化产品。

{"title":"Ultrasound-assisted hot water extraction of yellow leaves of Pu’er tea polysaccharides: Extraction process, characterization, antioxidant and hypoglycemic activity","authors":"Ao Zhao , Lina Sun , Fu Xu, Wendie Gan, Biaoying Guo, Lianzhou Jiang, Xia Wu","doi":"10.1016/j.ultsonch.2025.107653","DOIUrl":"10.1016/j.ultsonch.2025.107653","url":null,"abstract":"<div><div>Yellow leaves of Pu’er tea are classified as lower-grade Pu’er tea, and polysaccharides being its principal active components. Pu’er tea polysaccharides (PTPS) were optimally extracted from yellow leaves of Pu’er tea using ultrasound-assisted hot water extraction with the following parameters: solid-to-liquid ratio of 1:25 (w/v), ultrasonic temperature of 70 °C, ultrasonic power of 500 W, and ultrasonic time of 40 min. Two fractions, PTPS-4A and PTPS-5A, were clearly isolated and purified. Their antioxidant and hypoglycemic effects were compared in a lab after examining their structural features. PTPS-4A and PTPS-5A were mostly composed of fucose, rhamnose, arabinose, galactose, glucose, mannose, and glucuronic acid. They manifested as flexible chains and assumed a linear spline curve suggestive of an earthworm-like conformation. The nuclear magnetic resonance investigation found α- and β-glycosidic linkages (<em>δ</em>4.30–5.95 ppm and <em>δ</em>4.29–4.97 ppm, respectively) in PTPS-4A and PTPS-5A. PTPS-4A had enhanced DPPH and hydroxyl radical removal, with IC<sub>50</sub> values of 1.79 ± 0.07 mg/mL and 6.42 ± 0.16 mg/mL, respectively. The intermediate concentration value of 5.22 ± 0.08 mg/mL of PTPS-4A indicated a stronger inhibitory impact on α-glucosidase. PTPS-4A and PTPS-5A did not affect α-amylase in any way. The PTPS-4A fraction from this study may be further processed to create polysaccharide-based hypoglycemic and antioxidant products.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"123 ","pages":"Article 107653"},"PeriodicalIF":9.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145396330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced extraction of beetroot peel polyphenols using response surface methodology and their stabilization in W/O/W emulsions using whey protein isolates 响应面法提取甜菜根皮多酚及其在乳清分离蛋白W/O/W乳剂中的稳定性

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2025-12-01 Epub Date: 2025-10-21 DOI: 10.1016/j.ultsonch.2025.107638

Iqra Nasim , Nauman Khalid

This study aims to investigate the bioactive compounds in beetroot peel and their stabilization in W/O/W emulsions for potential use in future food industrial applications. The extraction of polyphenols, flavonoids, and antioxidants from beetroot peels was performed with the green extraction method, and their effects were determined through spectrophotometric methods. Box-Behnken Design was used for optimizing extraction parameters and model validation. The design suggested a quadratic model for all the responses. The minimum and maximum coded values examined for the experimental design included extraction time (10–30 min), sample concentration (1–5 %), and operating power (10–50 W). The W/O/W emulsions were prepared with varying concentrations of whey protein isolates (WPI) (1 % (E₁), 2 % (E₂), and 3 % (E₃) (w/w)). The emulsions were studied in terms of creaming index, viscosity, encapsulation efficiency, antioxidant determination, color analysis, droplet size distribution, and optical microscopy on samples stored for 0, 10, 20, and 30 days at 4 °C. The optimized conditions for maximum extraction of polyphenols were 21.72 min, 4.99 % sample concentration, and 49.76 W power. The yield of total polyphenols, total flavonoids, DPPH, and ABTS activity was 46.5 mg GAE/g DW, 10.9 mg QE/g, 66.3 %, and 89.6 % respectively. 3 % (w/w) WPI provided the highest color retention, oxidative and physical stability, and encapsulation efficiency. Overall, it was observed that all the independent factors played a significant role in the extraction of phytochemicals from beetroot peel extract and could be improved to maximize model responses. The formulated emulsion has potential for utilization in future food applications.

本研究旨在研究甜菜根皮中的生物活性化合物及其在W/O/W乳剂中的稳定性，以期在未来的食品工业中应用。采用绿色提取法提取甜菜根果皮中的多酚类、黄酮类和抗氧化剂，并采用分光光度法测定其提取效果。采用Box-Behnken设计优化提取参数并进行模型验证。设计建议对所有响应采用二次模型。实验设计的最小和最大编码值包括提取时间（10-30 min）、样品浓度（1- 5%）和工作功率（10-50 W）。分别用不同浓度的乳清分离蛋白（WPI） (1% （E1）、2% （E2）和3% (E3) （W /W）制备W/O/W乳状液。在4℃下分别保存0、10、20、30天，对乳剂的成乳指数、粘度、包封效率、抗氧化测定、颜色分析、液滴大小分布和光学显微镜进行研究。最佳提取条件为21.72 min，样品浓度为4.99%，功率为49.76 W。总多酚、总黄酮、DPPH和ABTS活性分别为46.5 mg GAE/g DW、10.9 mg QE/g、66.3%和89.6%。3% (w/w) WPI的保色性、氧化稳定性、物理稳定性和包封效率最高。综上所述，所有的独立因子对甜菜根皮提取物中植物化学物质的提取都有显著的影响，并且可以改进以最大化模型响应。该配方乳剂在未来的食品应用中具有潜在的应用价值。

{"title":"Enhanced extraction of beetroot peel polyphenols using response surface methodology and their stabilization in W/O/W emulsions using whey protein isolates","authors":"Iqra Nasim , Nauman Khalid","doi":"10.1016/j.ultsonch.2025.107638","DOIUrl":"10.1016/j.ultsonch.2025.107638","url":null,"abstract":"<div><div>This study aims to investigate the bioactive compounds in beetroot peel and their stabilization in W/O/W emulsions for potential use in future food industrial applications. The extraction of polyphenols, flavonoids, and antioxidants from beetroot peels was performed with the green extraction method, and their effects were determined through spectrophotometric methods. Box-Behnken Design was used for optimizing extraction parameters and model validation. The design suggested a quadratic model for all the responses. The minimum and maximum coded values examined for the experimental design included extraction time (10–30 min), sample concentration (1–5 %), and operating power (10–50 W). The W/O/W emulsions were prepared with varying concentrations of whey protein isolates (WPI) (1 % (E<sub>1</sub>), 2 % (E<sub>2</sub>), and 3 % (E<sub>3</sub>) (w/w)). The emulsions were studied in terms of creaming index, viscosity, encapsulation efficiency, antioxidant determination, color analysis, droplet size distribution, and optical microscopy on samples stored for 0, 10, 20, and 30 days at 4 °C. The optimized conditions for maximum extraction of polyphenols were 21.72 min, 4.99 % sample concentration, and 49.76 W power. The yield of total polyphenols, total flavonoids, DPPH, and ABTS activity was 46.5 mg GAE/g DW, 10.9 mg QE/g, 66.3 %, and 89.6 % respectively. 3 % (w/w) WPI provided the highest color retention, oxidative and physical stability, and encapsulation efficiency. Overall, it was observed that all the independent factors played a significant role in the extraction of phytochemicals from beetroot peel extract and could be improved to maximize model responses. The formulated emulsion has potential for utilization in future food applications.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"123 ","pages":"Article 107638"},"PeriodicalIF":9.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145450446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application and mechanism of ultrasonic-assisted extraction of ginkgo flavonol glycosides with natural deep eutectic solvent-based supramolecular solvents 天然深共晶溶剂基超分子溶剂超声辅助提取银杏黄酮醇苷的应用及机理研究

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2025-12-01 Epub Date: 2025-11-04 DOI: 10.1016/j.ultsonch.2025.107664

Han Yuan , Xiangzhou Li , Jun Zhou , Yanhong Yang , Wensheng Li , Peng Zhou

To address potential issues such as low efficiency, prolonged processing time, the environmental friendliness deficiency of traditional extraction processes of ginkgo flavonol glycosides, this study adopted an ultrasonic-assisted extraction of Ginkgo Flavonol Glycosides with natural deep eutectic solvent-based supramolecular solvent/equilibrium solution (NADES-SUPRAS/EqS). With the assistance of ultrasound, this method achieved an efficient and green extraction process, especially demonstrating significant advantages in reducing extraction time. Through experimental optimization, the optimal conditions were determined as follows: ultrasonic power 160 W, treatment duration 15 min, solid-to-liquid ratio 40 mg/mL, and extraction temperature 30 ℃. Under these conditions, the yield of Ginkgo Flavonol Glycosides reached 8.025 mg/g. Recovery experiments confirmed excellent recyclability of the NADES-SUPRAS/EqS solvent, achieving a flavonol glycoside recovery rate of 91.3 %. This approach holds significant potential for industrial-scale production of Ginkgo Flavonol Glycosides. Microstructural analysis revealed that the NADES-SUPRAS/EqS solvent formed normal micellar vesicles with a hydrophobic core and hydrophilic corona, and the combination of ultrasonic action could effectively disrupt the cell walls of Ginkgo leaves. Density functional theory (DFT)-based molecular modeling elucidated the extraction mechanism, demonstrating strong hydrogen bonding and van der Waals interactions between the NADES-SUPRAS/EqS solvent and rutin. The significance of this research lies in offering a reference framework for green and efficient ultrasonic-assisted extraction studies of natural bioactive compounds, which may provide a feasible technical solution for production of ginkgo flavonol glycosides.

针对传统银杏黄酮醇苷提取工艺效率低、加工时间长、环境友好性差等问题，采用天然深共晶溶剂基超分子溶剂/平衡溶液（NADES-SUPRAS/EqS）对银杏黄酮醇苷进行超声辅助提取。该方法在超声辅助下实现了高效、绿色的提取过程，尤其在缩短提取时间方面具有显著的优势。通过实验优化，确定最佳提取条件为：超声功率160 W，处理时间15 min，料液比40 mg/mL，提取温度30℃。在此条件下，银杏黄酮醇苷的得率可达8.025 mg/g。回收实验证实了NADES-SUPRAS/EqS溶剂具有良好的可回收性，黄酮醇苷的回收率为91.3%。该方法具有工业规模生产银杏黄酮醇苷的巨大潜力。微观结构分析表明，NADES-SUPRAS/EqS溶剂形成疏水核和亲水冕的正常胶束囊泡，超声联合作用可有效破坏银杏叶片细胞壁。基于密度泛函数理论（DFT）的分子模型阐明了萃取机理，表明NADES-SUPRAS/EqS溶剂与芦丁之间存在强氢键和范德华相互作用。本研究的意义在于为绿色高效的超声波辅助提取天然生物活性物质研究提供了参考框架，为银杏黄酮醇苷的生产提供了可行的技术解决方案。

{"title":"Application and mechanism of ultrasonic-assisted extraction of ginkgo flavonol glycosides with natural deep eutectic solvent-based supramolecular solvents","authors":"Han Yuan , Xiangzhou Li , Jun Zhou , Yanhong Yang , Wensheng Li , Peng Zhou","doi":"10.1016/j.ultsonch.2025.107664","DOIUrl":"10.1016/j.ultsonch.2025.107664","url":null,"abstract":"<div><div>To address potential issues such as low efficiency, prolonged processing time, the environmental friendliness deficiency of traditional extraction processes of ginkgo flavonol glycosides, this study adopted an ultrasonic-assisted extraction of Ginkgo Flavonol Glycosides with natural deep eutectic solvent-based supramolecular solvent/equilibrium solution (NADES-SUPRAS/EqS). With the assistance of ultrasound, this method achieved an efficient and green extraction process, especially demonstrating significant advantages in reducing extraction time. Through experimental optimization, the optimal conditions were determined as follows: ultrasonic power 160 W, treatment duration 15 min, solid-to-liquid ratio 40 mg/mL, and extraction temperature 30 ℃. Under these conditions, the yield of Ginkgo Flavonol Glycosides reached 8.025 mg/g. Recovery experiments confirmed excellent recyclability of the NADES-SUPRAS/EqS solvent, achieving a flavonol glycoside recovery rate of 91.3 %. This approach holds significant potential for industrial-scale production of Ginkgo Flavonol Glycosides. Microstructural analysis revealed that the NADES-SUPRAS/EqS solvent formed normal micellar vesicles with a hydrophobic core and hydrophilic corona, and the combination of ultrasonic action could effectively disrupt the cell walls of Ginkgo leaves. Density functional theory (DFT)-based molecular modeling elucidated the extraction mechanism, demonstrating strong hydrogen bonding and van der Waals interactions between the NADES-SUPRAS/EqS solvent and rutin. The significance of this research lies in offering a reference framework for green and efficient ultrasonic-assisted extraction studies of natural bioactive compounds, which may provide a feasible technical solution for production of ginkgo flavonol glycosides.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"123 ","pages":"Article 107664"},"PeriodicalIF":9.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145441407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound-powered bovine bone protein hydrolysate-flaxseed gum emulsions: modulation of stability, interfacial properties, and curcumin bioaccessibility 超声驱动的牛骨蛋白水解-亚麻籽胶乳剂：稳定性、界面特性和姜黄素生物可及性的调节

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2025-12-01 Epub Date: 2025-10-30 DOI: 10.1016/j.ultsonch.2025.107658

Niancheng Hong , Shengnan Liu , Yueyu Bai , Yaodi Zhu , Miaoyun Li , Lijun Zhao , Gaiming Zhao , Dong Liang

Designing stable and functional emulsions using natural emulsifiers remains a key challenge in the food industry, particularly due to the limited interfacial activity and weak compatibility of protein–polysaccharide systems under conventional processing methods. In this study, we prepared bovine bone protein hydrolysate–flaxseed gum (BBPH–FG) composite emulsions using ultrasound-assisted technology to address these challenges and to improve emulsion stability, interfacial behavior, and curcumin delivery performance. Ultrasonic power (0–1000 W) had a significant effect on emulsion properties, with the optimal results obtained at 750 W. At this power level, the droplet size decreased to 11.74 μm, the polydispersity index (PDI) to 0.291, and the zeta potential reached − 19.66 mV, indicating enhanced electrostatic repulsion and homogeneity. At this level, the interfacial protein adsorption rate and interfacial protein concentration increased to 79.85 % and 36.12 mg/m², forming a compact interfacial film that enhanced stability. After 25 days of storage, the 750 W-treated emulsions exhibited the lowest peroxide value (9.24 mg/L) and TBARS (1.25 mg/L), as well as the highest curcumin encapsulation efficiency (82.1 %) and bioaccessibility (71.37 %). This study demonstrates that moderate ultrasound power facilitates the molecular rearrangement and synergistic interaction of BBPH and FG, thereby enhancing emulsion functionality and providing a promising strategy for developing polysaccharide-based delivery systems.

使用天然乳化剂设计稳定和功能的乳剂仍然是食品工业的一个关键挑战，特别是由于传统加工方法下蛋白质-多糖体系的界面活性有限和相容性弱。在这项研究中，我们利用超声辅助技术制备了牛骨水解蛋白-亚麻籽胶（BBPH-FG）复合乳液，以解决这些挑战，并改善乳液的稳定性、界面行为和姜黄素的传递性能。超声功率（0 ~ 1000 W）对乳化液性能影响显著，750 W时效果最佳。在此功率下，微滴尺寸减小至11.74 μm，多分散性指数（PDI）降至0.291，zeta电位达到- 19.66 mV，表明静电斥力和均匀性增强。在此水平下，界面蛋白吸附率和界面蛋白浓度分别提高到79.85%和36.12 mg/m2，形成致密的界面膜，增强了稳定性。经750w处理的乳剂在25 d后，其过氧化值最低（9.24 mg/L）， TBARS最低（1.25 mg/L），姜黄素包封率最高（82.1%），生物可及性最高（71.37%）。该研究表明，适度的超声功率有助于BBPH和FG的分子重排和协同相互作用，从而增强乳状液的功能，为开发基于多糖的递送系统提供了一个有前途的策略。

{"title":"Ultrasound-powered bovine bone protein hydrolysate-flaxseed gum emulsions: modulation of stability, interfacial properties, and curcumin bioaccessibility","authors":"Niancheng Hong , Shengnan Liu , Yueyu Bai , Yaodi Zhu , Miaoyun Li , Lijun Zhao , Gaiming Zhao , Dong Liang","doi":"10.1016/j.ultsonch.2025.107658","DOIUrl":"10.1016/j.ultsonch.2025.107658","url":null,"abstract":"<div><div>Designing stable and functional emulsions using natural emulsifiers remains a key challenge in the food industry, particularly due to the limited interfacial activity and weak compatibility of protein–polysaccharide systems under conventional processing methods. In this study, we prepared bovine bone protein hydrolysate–flaxseed gum (BBPH–FG) composite emulsions using ultrasound-assisted technology to address these challenges and to improve emulsion stability, interfacial behavior, and curcumin delivery performance. Ultrasonic power (0–1000 W) had a significant effect on emulsion properties, with the optimal results obtained at 750 W. At this power level, the droplet size decreased to 11.74 μm, the polydispersity index (PDI) to 0.291, and the zeta potential reached − 19.66 mV, indicating enhanced electrostatic repulsion and homogeneity. At this level, the interfacial protein adsorption rate and interfacial protein concentration increased to 79.85 % and 36.12 mg/m<sup>2</sup>, forming a compact interfacial film that enhanced stability. After 25 days of storage, the 750 W-treated emulsions exhibited the lowest peroxide value (9.24 mg/L) and TBARS (1.25 mg/L), as well as the highest curcumin encapsulation efficiency (82.1 %) and bioaccessibility (71.37 %). This study demonstrates that moderate ultrasound power facilitates the molecular rearrangement and synergistic interaction of BBPH and FG, thereby enhancing emulsion functionality and providing a promising strategy for developing polysaccharide-based delivery systems.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"123 ","pages":"Article 107658"},"PeriodicalIF":9.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145405070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0