Ultrasonics Sonochemistry最新文献_第9页

Liposome-integrated ultrasound coupling subcritical water extraction for enhanced the efficiency and stability of Phyllanthus emblica polyphenols 脂质体-超声耦合亚临界水萃取法提高余甘子多酚的提取效率和稳定性。

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-12-09 DOI: 10.1016/j.ultsonch.2025.107717

Shuhui Liang , Xinyi Luo , Zexin Chen , Yushi Gong , Yong Hu , Fenglin Song , Yongguang Bi , Dongmei Li , Juan Guo

Ultrasound coupling subcritical water extraction (USWE) was developed to extract polyphenols from Phyllanthus emblica pomace (PPEPs), and extraction parameters affecting the yield of PPEPs were systematically optimized. USWE was comprehensively evaluated in terms of extraction parameters, yield, antioxidant capacity, major bioactive components, and infrared characteristics of PPEPs, and compared with four other extraction methods. Microstructural changes in the pomace were examined using scanning electron microscopy (SEM) to elucidate the interactions between the extraction process and the plant matrix. Finally, to address the issues of the instability of PPEPs and their low bioavailability, liposomal encapsulation was performed and the physicochemical properties were evaluated. Results demonstrated that the yield of PPEPs from USWE was 1.8-fold and 1.35-fold higher than those from solvent extraction (SE) and subcritical water extraction (SWE), respectively. Furthermore, PPEPs from USWE exhibited the strongest antioxidant activity and higher levels of six major bioactive compounds. SEM analysis revealed a significant increase in porosity and enlarged pores in USWE-treated pomace. Additionally, Phyllanthus emblica polyphenol liposomes (PPEPL) were prepared by thin-film dispersion technique. PPEPL showed a high encapsulation efficiency of 83.07 ± 0.09 % and retained structural integrity after 4 weeks of storage at 4 °C. PPEPL exhibited enhanced antioxidant activity compared to free PPEPs. The IC₅₀ values for scavenging DPPH·, ABTS·⁺, and hydroxyl radicals were 3.2-, 3.3-, and 1.6-fold lower, respectively. In summary, integrating USWE with liposome technology provides an efficient strategy for obtaining stable, high-quality bioactive PPEPs.

采用超声耦合亚临界水萃取法（USWE）提取余甘子果渣中的多酚，并对影响余甘子果渣得率的提取工艺参数进行了系统优化。从提取参数、得率、抗氧化能力、主要生物活性成分、红外特性等方面对USWE进行综合评价，并与其他4种提取方法进行比较。利用扫描电子显微镜（SEM）研究了渣的微观结构变化，以阐明提取过程与植物基质之间的相互作用。最后，为了解决pppep的不稳定性和生物利用度低的问题，进行了脂质体包封，并对其理化性质进行了评价。结果表明，与溶剂萃取法（SE）和亚临界水萃取法（SWE）相比，USWE法的ppps得率分别提高了1.8倍和1.35倍。此外，来自USWE的pep表现出最强的抗氧化活性和六种主要生物活性化合物的较高水平。SEM分析显示，uswe处理的渣土孔隙率显著增加，孔隙扩大。此外，采用薄膜分散法制备了余甘子多酚脂质体（PPEPL）。PPEPL包封率为83.07±0.09%，在4℃下保存4周后仍保持结构完整性。与游离ppep相比，PPEPL表现出更强的抗氧化活性。清除DPPH·、ABTS·+和羟基自由基的IC50值分别降低了3.2倍、3.3倍和1.6倍。综上所述，将USWE与脂质体技术相结合为获得稳定、高质量的生物活性ppp提供了一种有效的策略。

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引用次数: 0

Rotational cavitator: advances and applications in cavitation-enhanced technologies 旋转空化器：空化增强技术的进展和应用

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-12-19 DOI: 10.1016/j.ultsonch.2025.107727

Yu-Hang Zhang , Zhi-Ying Zheng , David Ezekoye , Lu Wang , Li-Ming Yao , Vladimir A. Kulagin , Jian Wu

Driven by the increasing demand for efficient, energy-saving and sustainable processing technologies, rotational cavitators have shown considerable promise across a range of industrial applications. By inducing intense shear forces and turbulent flow through high-speed rotation in liquid media, rotational cavitation enables strong cavitation effects under controlled conditions, thereby intensifying transport and reaction processes under lower energy input. This review systematically examines the fundamentals, cavitation characteristics and structural evolution of rotational cavitators, with a particular focus on their applications in biofuel production, droplet emulsification, food processing, wastewater treatment and other process intensification. The review comprehensively discusses the benefits of rotational cavitation in multiple application domains, outlines current research progress and emerging trends, and provides theoretical insights and practical guidance for future research and industrial implementation.

在对高效、节能和可持续加工技术日益增长的需求的推动下，旋转空化器在一系列工业应用中显示出相当大的前景。旋转空化通过在液体介质中高速旋转产生强烈的剪切力和湍流，在可控条件下产生强烈的空化效应，从而在低能量输入下强化输运和反应过程。本文系统地介绍了旋转空化器的基本原理、空化特征和结构演变，重点介绍了旋转空化器在生物燃料生产、液滴乳化、食品加工、废水处理等过程强化中的应用。综述全面讨论了旋转空化在多个应用领域的优势，概述了当前的研究进展和新兴趋势，并为未来的研究和工业实施提供了理论见解和实践指导。

引用次数: 0

Ultrasonication as a tool to develop starch nanoparticles from macrophytes to tailor starch properties 超声波加工技术对Dal湖植物淀粉制备绿色纳米生物材料的比较评价

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-12-06 DOI: 10.1016/j.ultsonch.2025.107711

Romee Jan , Adil Gani , Asima Shah , Irfan Ahmad Raina , Asir Gani

Starch is a popular type of biopolymer that has multiple uses in industry and there is an increased interest in searching the possible sustainable sources in underutilized plants. The paper was aimed at extracting and characterizing starch from macrophyte narrowleaf cattail (Typha angustifolia) and lotus (Nelumbo nucifera) of Dal Lake, Kashmir. The two species possessed high starch content of 67.11 ± 1.03 % and 66.18 ± 1.04 % with moderate amylose content of 13.67 ± 0.70 % and 13.45 ± 0.11 %, respectively, indicating their alternative use in the food industry. Proximate analysis showed that cattail starch contained more protein (6.28 ± 0.55 %) and fat (2.15 ± 0.03 %) than lotus, indicating that the two species are functionally different and may be applied in specific functional applications. Ultrasonic processing, a green efficient method was used where the acoustic cavitation by high frequency sound waves improved mass transfer and destruction of plant cell walls, leading to structural changes in the extracted starches thereby enhancing the functional and physicochemical properties. Ultrasonic nano-reduction minimized particle size and improved the colloidal stability of the particles as shown by the low polydispersity index and high negative zeta potential. Such physicochemical improvements would increase starch functionality in biodegradable packaging, pharmaceutical, and food technology applications. This study identifies the untapped potential of macrophytes from Dal Lake as renewable sources of biodegradable starch, encouraging the sustainable use of local biodiversity and valuable addition products, which boosts the economic growth of the area.

淀粉是一种流行的生物聚合物，在工业上有多种用途，人们对在未充分利用的植物中寻找可能的可持续来源越来越感兴趣。本文旨在从克什米尔达尔湖的大型植物狭叶香蒲（Typha angustifolia）和荷花（Nelumbo nucifera）中提取淀粉并对其进行表征。两种植物淀粉含量分别为67.11±1.03%和66.18±1.04%，直链淀粉含量分别为13.67±0.70%和13.45±0.11%，具有较高的应用价值。近似分析表明，香蒲淀粉的蛋白质含量（6.28±0.55%）和脂肪含量（2.15±0.03%）均高于荷花，说明两者在功能上存在差异，可能具有特定的功能应用。超声波处理是一种绿色高效的方法，其中高频声波的声空化改善了植物细胞壁的传质和破坏，导致提取的淀粉结构发生变化，从而提高了功能和物理化学性质。超声纳米还原使颗粒尺寸最小化，提高了颗粒的胶体稳定性，表现为低的多分散性指数和高的负zeta电位。这种物理化学改进将增加淀粉在可生物降解包装、制药和食品技术应用中的功能。本研究确定了Dal湖的大型植物作为可生物降解淀粉的可再生资源的未开发潜力，鼓励了当地生物多样性和有价值的附加产品的可持续利用，从而促进了该地区的经济增长。

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引用次数: 0

Correlation between the degree of ultrasound-induced cell disintegration and the extraction efficiency of intracellular compounds from purple sweet potato 紫甘薯超声诱导细胞崩解程度与细胞内化合物提取效率的关系

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-11-28 DOI: 10.1016/j.ultsonch.2025.107699

Meng Xu , Wangting Zhou , Yilin Li , Muci Wu , Rui Zhang , Jingren He , Chen Liu

Ultrasound (US) is an effective intensified extraction technology for natural plant resources, but detailed microscale investigations into US-induced plant cell disintegration are lacking. This study explored the correlation between US-induced (P = 0–800 W, t = 0–40 min) cell disintegration degree and the extraction efficiency of intracellular components from purple sweet potato, also discussing extraction selectivity and visualizing the cell micro-disintegration process. Cell disintegration degree was estimated via electrical conductivity (cell permeabilization index, Z_i) and fractal dimension analysis of damaged cells (cell wall disintegration index, Z_d). Extraction efficiency was evaluated by using the extraction indexes of carbohydrate (Z_c), protein (Z_p), and total phenolic compound (Z_TPC). Results indicated that US markedly enhanced cell permeabilization and intracellular components release. For example, at the highest intensity (800 W, 40 min), the enhancement in carbohydrate, protein and TPC contents were approximately 2 to 7 folds, compared to untreated sample (0 W, 40 min). Extraction efficiencies depended on the applied P and t, with the extractability order was carbohydrate > protein > TPC at each power. Different non-linear correlations between Z_d with Z_i, Z_p, Z_c, and Z_TPC, reflecting the differences in the release behaviors of these water-soluble components after US treatment. Additionally, US favored carbohydrate extraction over protein, but stronger US intensity resulted in lower extraction selectivity. The visual microscale model showed that increasing P elevated cell surface acoustic pressure, cell stress and volume strain. Cell micro-disintegration process would initiate at the side and end faces, then gradually spread to the edges.

超声（US）是一种有效的植物资源强化提取技术，但对超声诱导植物细胞崩解的微观研究尚缺乏。本研究探讨了紫外光诱导（P = 0 ~ 800 W, t = 0 ~ 40 min）细胞崩解程度与紫甘薯胞内成分提取效率的关系，并探讨了提取的选择性和细胞微崩解过程的可视化。通过电导率（细胞渗透性指数，Zi）和受损细胞的分形维数（细胞壁崩解指数，Zd）来估计细胞的崩解程度。以碳水化合物（Zc）、蛋白质（Zp）和总酚类化合物（ZTPC）为提取指标评价提取效率。结果表明，US能显著提高细胞的通透性和细胞内成分的释放。例如，在最高强度（800 W, 40 min）下，碳水化合物、蛋白质和TPC含量比未处理样品（0 W, 40 min）提高了约2至7倍。提取效率与施加的P和t有关，各功率下的可提取性顺序为碳水化合物>；蛋白质>； TPC。Zd与Zi、Zp、Zc和ZTPC之间存在不同的非线性相关关系，反映了这些水溶性成分在US处理后释放行为的差异。此外，美国更倾向于碳水化合物而不是蛋白质的提取，但更强的美国强度导致较低的提取选择性。视觉微尺度模型显示，P的增加使细胞表面声压、细胞应力和体积应变升高。细胞微崩解过程从侧面和端面开始，逐渐向边缘扩散。

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引用次数: 0

Effect of ultrasound pretreatment assisted drying methods on structural and thermal properties of soy protein isolate 超声预处理辅助干燥方法对大豆分离蛋白结构和热性能的影响

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-11-26 DOI: 10.1016/j.ultsonch.2025.107696

Naveed Mahmood , Chang Zheng , Xiaoyan Song , Yuyang Huang , Sajad Ali , Zeeshan Munir , Farzaneh Khorsandi , Yang Li , Fraz Ahmad Khan , Hafiz Mutther Javed

Soy protein isolate, a essential component in various food products, can be greatly impacted by the drying process, influencing its quality and functionality. This study evaluates the effect of ultrasound pretreatments (5, 10, and 15 min at 350 W) and different drying techniques, namely, freeze drying (FD), spray drying (SD) and oven drying (OD) on structural and functional properties of soy protein isolate (SPI) powder. Among all drying conditions, maximum peak temperature T_d (175.31 °C) was achieved with FD after 15 min of ultrasound pretreatment. Sodium dodecyl sulphate–polyacrylamide gel electrophoresis (SDS-PAGE) analysis revealed that ultrasound pretreatment significantly affected protein fragmentation in soy protein isolate (SPI), altering its molecular weight and exhibiting distinct bands compared to control (with distinct bands around 48 kDa and 75 kDa range); demonstrating the most prominent effect of ultrasonic treatment, which further enhanced functional properties. Notably, surface hydrophobicity (H₀) of SPI was significantly higher after ultrasound pretreatments compared to their control samples, suggesting that this application time effectively enhanced the exposure of hydrophobic groups. The relative crystallinity of FD-control, SD-control and OD-control samples were decreased by 6.83 % for FD, 8.14 % for SD and 5.30 % for OD after 15 min of ultrasound pretreated drying, respectively. Ultrasound pretreatment significantly reduced contents of off-flavor compounds, such as 3,5-Octadien-2-one, Decanal, (E)-2-octenal and 2-Pentylfuran in SPI. Moreover, relative content of 3,5-Octadien-2-one in the major volatile off-flavor compound of FD dried SPI reduced from 2.27 % to 1.00 %, 1.05 %, and 0.96 % at 5-, 10-, and 15-minute ultrasound (350 W) application times, respectively. These findings provided valuable insights into selecting appropriate ultrasound pretreated drying techniques to optimize the quality and performance of SPI in various applications.

大豆分离蛋白是各种食品中必不可少的成分，干燥过程对其质量和功能的影响很大。本研究评价了超声预处理（5、10和15 min， 350 W）和不同干燥技术，即冷冻干燥（FD）、喷雾干燥（SD）和烘箱干燥（OD）对大豆分离蛋白（SPI）粉末结构和功能特性的影响。在所有干燥条件下，超声预处理15 min后，FD达到最高峰值温度Td（175.31 °C）。十二烷基硫酸钠-聚丙烯酰胺凝胶电泳（SDS-PAGE）分析显示，超声预处理显著影响大豆分离蛋白（SPI）的蛋白片段化，改变了其分子量，与对照组相比呈现出明显的条带（在48 kDa和75 kDa范围内存在明显的条带）；超声处理的效果最为突出，进一步增强了功能性能。值得注意的是，超声预处理后的SPI的表面疏水性（H0）明显高于对照样品，这表明该应用时间有效地增强了疏水性基团的暴露。超声预处理干燥15 min后，FD对照、SD对照和OD对照样品的相对结晶度分别降低6.83 %、8.14 %和5.30 %。超声预处理显著降低了SPI中3,5-辛烯-2- 1、癸醛、(E)-2-辛烯醛和2-戊基呋喃等异味化合物的含量。此外，FD干燥SPI的主要挥发性异味化合物中3,5-八烯二烯-2- 1的相对含量在5、10和15分钟超声波（350 W）作用下分别从2.27 %降至1.00 %、1.05 %和0.96 %。这些发现为选择合适的超声预处理干燥技术以优化SPI在各种应用中的质量和性能提供了有价值的见解。

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引用次数: 0

Review of ultrasonication-assisted Fenton processes for degrading aqueous pollutants 超声辅助Fenton法降解水中污染物的研究进展

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-12-16 DOI: 10.1016/j.ultsonch.2025.107725

Slimane Merouani , Aissa Dehane , Oualid Hamdaoui , Muthupandian Ashokkumar

Ultimate oxidation has attracted growing consideration due to its capacity to generate extremely reactive oxidants, such as OH. In particular, Fenton chemistry and ultrasonication (US) techniques have demonstrated significant potential for degrading resistant contaminants in wastewater. The US/Fenton technique involves ultrasonication with Fenton’s reagent to enhance OH radical generation and improve treatment efficacy. This review examines the theoretical foundations, operational effectiveness, and recent developments associated with US/Fenton. First, the report provides an overview of the Fenton, ultrasonication, and US/Fenton mechanisms, both individually and in combination. Then, it analyzes how variables such as ultrasonication frequency, energy input, pH, and reagent dosage influence performance. Next, the discussion turns to novel adaptations, such as US/photo-Fenton and US/electro-Fenton methods, and their roles in sludge treatment and related applications. Lastly, the review addresses the current challenges to its widespread implementation and outlines future research needs. Overall, the review emphasizes the recent progress and promising potential of US/Fenton as a robust wastewater remediation approach.

由于其产生极具活性的氧化剂（如OH）的能力，最终氧化引起了越来越多的关注。特别是，Fenton化学和超声波（US）技术已经证明了降解废水中抗性污染物的巨大潜力。US/Fenton技术是用Fenton试剂进行超声处理，增强OH自由基的生成，提高治疗效果。本文审查了与US/Fenton相关的理论基础、操作有效性和最新发展。首先，该报告概述了Fenton、超声波和US/Fenton机制，无论是单独的还是组合的。然后，分析了超声频率、能量输入、pH、试剂用量等变量对性能的影响。接下来，讨论转向新的适应性，如US/photo-Fenton和US/electro-Fenton方法，以及它们在污泥处理和相关应用中的作用。最后，该综述指出了其广泛实施的当前挑战，并概述了未来的研究需求。总体而言，综述强调了US/Fenton作为一种强大的废水修复方法的最新进展和前景。

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引用次数: 0

Advances in ultrasound-assisted drug delivery and clinical application 超声辅助给药及其临床应用研究进展。

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-09-11 DOI: 10.1016/j.ultsonch.2025.107557

Limei Lai , Xiaoyu Han , Yunkai Tang , Jianqiao Zhou , Wenguo Cui

Ultrasound (US) is a non-invasive physical stimulus characterized by high spatiotemporal precision and deep tissue penetration, offering distinct advantages for drug delivery applications. This review provides a comprehensive overview of recent advances and future directions in ultrasound-assisted drug delivery (USADD) for diseases treatment. It systematically summarizes the fundamental mechanisms of USADD, including thermal effects, cavitation effects, and mechanical effects, and examines the design strategies of US-responsive carrier materials such as microbubbles, liposomes, polymeric micelles. Particular emphasis is placed on the therapeutic applications of USADD in a wide range of diseases, including tissue regeneration, cancer therapy, anti-infective therapies, cardiovascular disorders, immune-metabolic diseases, and conditions affecting the sensory organs. Finally, key challenges are discussed in clinical translation, including biosafety, carrier stability, and intelligent regulation, and future perspectives are outlined on the potential of USADD systems to achieve precise and personalized therapeutic interventions.

超声（US）是一种非侵入性的物理刺激，具有高时空精度和深组织穿透性的特点，在药物传递应用中具有明显的优势。本文综述了超声辅助给药（USADD）在疾病治疗中的最新进展及未来发展方向。系统总结了USADD的基本机理，包括热效应、空化效应和机械效应，并探讨了微泡、脂质体、聚合物胶束等USADD响应载体材料的设计策略。特别强调的是USADD在多种疾病中的治疗应用，包括组织再生、癌症治疗、抗感染治疗、心血管疾病、免疫代谢疾病和影响感觉器官的疾病。最后，讨论了临床转化中的关键挑战，包括生物安全性、载体稳定性和智能调控，并概述了USADD系统实现精确和个性化治疗干预的潜力。

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引用次数: 0

Ultrasound-Propelled ferroptosis catalytic amplification for Active-targeting sonodynamic anti-tumor therapy with Concurrent Photoacoustic/MRI visualization 超声推动下的铁下垂催化放大用于主动靶向声动力抗肿瘤治疗与光声/MRI同步可视化

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-12-21 DOI: 10.1016/j.ultsonch.2025.107731

Qiqing Chen , Lin Xie , Yangcheng Yao , Qiang Zhou , Yan Lin , Dandan Sun , Zhuole Wu , Dong Xie , Xiangxiang Jing

Sonodynamic therapy (SDT) faces significant challenges in treating aggressive malignancies due to inherent apoptotic resistance. To address this, we developed a multifunctional nanoliposome designed for mitochondrial targeting and synergistic induction of dual cell death pathways. Co-loaded with the sonosensitizer HMME and an iron-based Fenton catalyst, the nanoparticle exhibits glutathione-responsive disassembly and promotes robust reactive oxygen species generation under ultrasound irradiation. This leads to potent lipid peroxidation and ferroptosis, effectively bypassing conventional resistance mechanisms. The platform further integrates dual-modal magnetic resonance and photoacoustic imaging capabilities, enabling precise tumor delineation and real-time treatment monitoring. Constructed entirely from clinically approved lipid components, our nanoplatform demonstrates excellent biocompatibility and achieves complete tumor regression in murine models without significant systemic toxicity. This work provides a comprehensive theranostic strategy that combines catalytic amplification with multimodal imaging, offering a clinically translatable approach for the precision treatment of therapy-resistant malignancies.

声动力疗法（SDT）在治疗侵袭性恶性肿瘤中由于固有的细胞凋亡抵抗而面临重大挑战。为了解决这个问题，我们开发了一种多功能纳米脂质体，用于线粒体靶向和双细胞死亡途径的协同诱导。该纳米颗粒与声敏剂HMME和铁基Fenton催化剂共负载，在超声照射下表现出谷胱甘肽反应性分解，并促进活性氧的产生。这导致强有力的脂质过氧化和铁下垂，有效地绕过传统的抵抗机制。该平台进一步集成了双模态磁共振和光声成像能力，实现了精确的肿瘤描绘和实时治疗监测。我们的纳米平台完全由临床批准的脂质成分构建，具有良好的生物相容性，在小鼠模型中实现了完全的肿瘤消退，而没有明显的全身毒性。这项工作提供了一种综合的治疗策略，将催化放大与多模态成像相结合，为治疗耐药恶性肿瘤的精确治疗提供了一种临床可翻译的方法。

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引用次数: 0

Preparation and characterization of ultrasound-mediated Ocimum basilicum L. essential oil nanoemulsion and its application in meat preservation 超声介导罗勒精油纳米乳的制备、表征及其在肉类保鲜中的应用

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-12-13 DOI: 10.1016/j.ultsonch.2025.107721

Yue Wang , Weixuan Pan , Xiangjun Yang , Ende Song , Hui Zhang , Yiming Liu , Kehui Wang , Huiwen Wu , Qi Liu

In this study, a stable basil oil nanoemulsion was prepared by emulsifier-assisted ultrasonication. The optimized formulation exhibited excellent physical stability under ambient, refrigerated (4 °C), and heated (55 °C) conditions. It demonstrated strong antibacterial activity against E. coli and S. aureus, inducing membrane disruption and oxidative stress, as evidenced by elevated ROS and MDA levels. The nanoemulsion also showed significant antioxidant capacity, scavenging 95 % of DPPH and 86 % of ABTS radicals and achieving a FRAP value of 14.6 µmol/g at 200 µg/mL. Cytotoxicity analysis confirmed high biocompatibility, with cell viability exceeding 83 % in L02 and BEAS-2B cells at 16 mg/mL. When applied to beef packaging, the nanoemulsion effectively maintained pH, reduced microbial counts, and suppressed TVB-N accumulation, thereby prolonging meat freshness. These findings highlight its potential as a multifunctional preservative for food and biomedical applications.

本研究采用乳化剂辅助超声法制备了稳定的罗勒油纳米乳。优化后的配方在室温、冷藏（4 °C）和加热（55 °C）条件下均表现出优异的物理稳定性。它对大肠杆菌和金黄色葡萄球菌具有很强的抗菌活性，可以诱导膜破坏和氧化应激，这可以通过提高ROS和MDA水平来证明。纳米乳还显示出显著的抗氧化能力，清除95 %的DPPH和86 %的ABTS自由基，在200 µg/mL时达到14.6 µmol/g的FRAP值。细胞毒性分析证实了高的生物相容性，在16 mg/mL浓度下，L02和BEAS-2B细胞的细胞存活率超过83 %。当应用于牛肉包装时，纳米乳有效地维持了pH值，减少了微生物数量，抑制了TVB-N的积累，从而延长了肉类的新鲜度。这些发现突出了其作为食品和生物医学用途的多功能防腐剂的潜力。

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引用次数: 0

Ultrasonic cavitation-induced radical processes for tetracycline degradation and Cr(VI) reduction: Highlighting the pivotal role of Cr(V) intermediates 超声空化诱导四环素降解和Cr（VI）还原的自由基过程：突出Cr(V)中间体的关键作用

IF 9.7 1区化学 Q1 ACOUSTICS

Ultrasonics Sonochemistry

Pub Date : 2026-01-01 Epub Date: 2025-12-09 DOI: 10.1016/j.ultsonch.2025.107713

Daokui Li , Binhui Luo , Feng Hong , Ruiping Li , Yuanfei Lv , Yingping Huang , Di Huang

Tetracycline (TC) and Cr(VI) often co-occur in wastewaters, where their synergistic toxicity and contrasting redox behaviors complicate remediation. In this study, ultrasonic cavitation was employed as a employed as a green and efficient process to simultaneously degrade TC and reduce Cr(VI). Under optimal conditions (20 kHz, 12 mm probe, 131 μm amplitude, 308 K), TC and Cr(VI) removal reached 62.9 % and 70.8 % within 2 h, respectively. The synergistic mechanism was elucidated through radical quenching, electron paramagnetic resonance (EPR) spectroscopy, and complementary computational fluid dynamics (CFD) simulations and density functional theory (DFT) calculations. Cavitation bubble collapse generated both oxidative and reductive radicals, enabling concurrent oxidation and reduction. Radical identification showed that ·O₂^– and ·H were the dominant reductants responsible for Cr(VI) reduction, whereas ¹O₂ and ·OH primarily controlled TC degradation. CFD simulations further demonstrated that mechanical energy, internal energy, and bubble growth rate during cavitation were positively correlated with radical generation. Importantly, experimental evidence suggested that Cr(VI) promoted the conversion of ·O₂^– into ¹O₂, establishing a coupled radical pathway that linked metal detoxification with antibiotic degradation. Furthermore, Cr(V) intermediates were detected as key transient species, exhibiting strong oxidative capacity toward TC and accelerating Cr(VI) reduction. Complementary DFT calculations confirmed that the coexistence of TC and ·H markedly lowered the energy barrier of Cr(VI) reduction. Overall, this work provides new mechanistic insight into radical transformation and metal-organic coupling under ultrasonic cavitation, and highlights its potential as a sustainable strategy for treating waters co-contaminated with metals and antibiotics.

四环素（TC）和Cr（VI）经常共存于废水中，它们的协同毒性和不同的氧化还原行为使修复变得复杂。在本研究中，超声波空化是一种绿色高效的工艺，可以同时降解TC和降低Cr（VI）。在最佳条件（20 kHz， 12 mm探针，131 μm振幅，308 K）下，2 h内对TC和Cr（VI）的去除率分别达到62.9%和70.8%。通过自由基猝灭、电子顺磁共振（EPR）谱、互补计算流体力学（CFD）模拟和密度泛函理论（DFT）计算，阐明了协同机理。空化泡破裂产生氧化自由基和还原自由基，使氧化和还原同时发生。自由基鉴定表明，·O2-和·H是Cr（VI）还原的主要还原剂，而1O2和·OH主要控制TC的降解。CFD模拟进一步表明，空化过程中的机械能、内能和气泡生长速率与自由基生成呈正相关。重要的是，实验证据表明，Cr（VI）促进了·O2-转化为1O2，建立了一个将金属解毒与抗生素降解联系起来的耦合自由基途径。此外，Cr(V)中间体是关键的瞬态物质，对TC表现出很强的氧化能力，加速了Cr（VI）的还原。互补DFT计算证实，TC和·H的共存显著降低了Cr（VI）还原的能垒。总的来说，这项工作为超声空化作用下的自由基转化和金属-有机偶联提供了新的机制见解，并突出了其作为处理金属和抗生素共污染水的可持续策略的潜力。

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