Pub Date : 2025-02-25DOI: 10.1016/j.ultsonch.2025.107292
Shuang Jiang , Xiaotian Wu , Xuepeng Shi , Yuanqiu Mu , Li Zhang , Shulu Zhang , Lin Wei , Zheng Feng , Yinze Zhong , Xinhui Huang , Yeqing Xu , Shah Syed Faizan Ali , Zhaonan Xu , Xiaotong Wang , Chunli Gan , Zhibin Wang , Yanan Sun , Chunjuan Yang
Sanguisorba officinalis L. (S. officinalis) has been widely distributed in various regions of China and holds significant potential for various applications. However, limited studies have focused on S. officinalis polysaccharides (SOPs) and their biological activities. Utilizing response surface methodology (RSM), the process of ultrasonic-assisted extraction of SOPs was optimized. The optimal conditions were 270.2 W, 42.4 mL/g, and 47.7 min. Through separation and purification, a neutral polysaccharide named SOUP-1 was obtained. SOUP-1 (17.1 kDa) mainly includes glucose and a few galactose, mannose, and arabinose. The main chain of SOUP-1 is primarily → 4)-α-D-Glcp-(1 → 4,6)-α-D-Glcp-(1 → substituted at C6 with branch chain → 6)-α-D-Glcp-(1 → . Furthermore, SOUP-1 showed antioxidant activity, including scavenging activities of hydroxyl radicals and DPPH. It also enhances macrophage phagocytic activity and modulates the expression of inflammatory cytokines such as TNF-α and IL-6. Additionally, this study first discovered the hemostatic activity of SOUP-1. This study provides theoretical support for the potential applications and further research of SOPs. It provides a basis for the development of SOPs as novel natural-source immunomodulators in the food and pharmaceutical industries.
{"title":"Extraction of Sanguisorba officinalis L. polysaccharide by ultrasound-assisted extraction: structural characterization, antioxidant, hemostatic and immunological activity","authors":"Shuang Jiang , Xiaotian Wu , Xuepeng Shi , Yuanqiu Mu , Li Zhang , Shulu Zhang , Lin Wei , Zheng Feng , Yinze Zhong , Xinhui Huang , Yeqing Xu , Shah Syed Faizan Ali , Zhaonan Xu , Xiaotong Wang , Chunli Gan , Zhibin Wang , Yanan Sun , Chunjuan Yang","doi":"10.1016/j.ultsonch.2025.107292","DOIUrl":"10.1016/j.ultsonch.2025.107292","url":null,"abstract":"<div><div><em>Sanguisorba officinalis</em> L. (<em>S</em>. <em>officinalis</em>) has been widely distributed in various regions of China and holds significant potential for various applications. However, limited studies have focused on <em>S</em>. <em>officinalis</em> polysaccharides (SOPs) and their biological activities. Utilizing response surface methodology (RSM), the process of ultrasonic-assisted extraction of SOPs was optimized. The optimal conditions were 270.2 W, 42.4 mL/g, and 47.7 min. Through separation and purification, a neutral polysaccharide named SOUP-1 was obtained. SOUP-1 (17.1 kDa) mainly includes glucose and a few galactose, mannose, and arabinose. The main chain of SOUP-1 is primarily → 4)-α-D-Glcp-(1 → 4,6)-α-D-Glcp-(1 → substituted at C6 with branch chain → 6)-α-D-Glcp-(1 → . Furthermore, SOUP-1 showed antioxidant activity, including scavenging activities of hydroxyl radicals and DPPH. It also enhances macrophage phagocytic activity and modulates the expression of inflammatory cytokines such as TNF-α and IL-6. Additionally, this study first discovered the hemostatic activity of SOUP-1. This study provides theoretical support for the potential applications and further research of SOPs. It provides a basis for the development of SOPs as novel natural-source immunomodulators in the food and pharmaceutical industries.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"115 ","pages":"Article 107292"},"PeriodicalIF":8.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-25DOI: 10.1016/j.ultsonch.2025.107286
Waseem Khalid , Imed E. Benmebarek , Kanza Saeed , Hyrije Koraqi , Andres Moreno , Robert Mugabi , Gulzar Ahmad Nayik , Tuba Esatbeyoglu
Garlic sprouts have nutritional and culinary significances due to good source of chemical compounds. The present study aimed to determine the optimized condition for maximum extraction of polyphenols from garlic sprouts through RSM (response surface methodology). However, the proximate, color and microbial analysis were performed on the freeze-dried garlic sprouts. The influences of extraction time (3–9 min), amplitude (50–90 %), ethanol concentration (25–75 %) and solid–liquid ratio (20–40 g/mL) on the extraction yield and total phenolic content (TPC) were investigated. The highest yield was observed on time (9 min), amplitude (70 %), ethanol (25 %) and solid–liquid ratio (30 g/mL) whereas the maximum TPC were measured on time (3 min), amplitude (70 %), ethanol (75 %) and solid–liquid ratio (30 g/mL). The optimal extraction conditions were 5.20 min, 61.1 % ethanol, 71.4 % amplitude and 30.6 g/mL solid–liquid ratio. However, the estimated results of the study are in accordance with the experimental outputs. In addition, chromatographic measurement showed the characterization of polyphenols in garlic sprout extract. Garlic can be fruitful in pharmaceutical and food industries due to a good source of bioactive compounds.
{"title":"Influence of ultrasound-assisted extraction of bioactives from garlic (Allium sativum) sprouts using response surface methodology","authors":"Waseem Khalid , Imed E. Benmebarek , Kanza Saeed , Hyrije Koraqi , Andres Moreno , Robert Mugabi , Gulzar Ahmad Nayik , Tuba Esatbeyoglu","doi":"10.1016/j.ultsonch.2025.107286","DOIUrl":"10.1016/j.ultsonch.2025.107286","url":null,"abstract":"<div><div>Garlic sprouts have nutritional and culinary significances due to good source of chemical compounds. The present study aimed to determine the optimized condition for maximum extraction of polyphenols from garlic sprouts through RSM (response surface methodology). However, the proximate, color and microbial analysis were performed on the freeze-dried garlic sprouts. The influences of extraction time (3–9 min), amplitude (50–90 %), ethanol concentration (25–75 %) and solid–liquid ratio (20–40 g/mL) on the extraction yield and total phenolic content (TPC) were investigated. The highest yield was observed on time (9 min), amplitude (70 %), ethanol (25 %) and solid–liquid ratio (30 g/mL) whereas the maximum TPC were measured on time (3 min), amplitude (70 %), ethanol (75 %) and solid–liquid ratio (30 g/mL). The optimal extraction conditions were 5.20 min, 61.1 % ethanol, 71.4 % amplitude and 30.6 <!--> <!-->g/mL solid–liquid ratio. However, the estimated results of the study are in accordance with the experimental outputs. In addition, chromatographic measurement showed the characterization of polyphenols in garlic sprout extract. Garlic can be fruitful in pharmaceutical and food industries due to a good source of bioactive compounds.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"115 ","pages":"Article 107286"},"PeriodicalIF":8.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this study, laboratory-scale Pinned Disc Rotary Generator of Hydrodynamic Cavitation was used to treat waste-activated sludge with a Total Solids concentration of 0.7 %. Five different rotor–stator arrangements were tested, focusing on waste-activated sludge physicochemical and rheological parameters of industrial relevance: general chemical analysis, rheometry, dewaterability, interfacial tension, UV–Vis and FTIR spectroscopy. Radical formation in all five arrangements was confirmed using salicylic acid dosimetry before sample testing. Three of the arrangements generated twice the radical concentration of the other two and achieved a disintegration degree three times higher (17 % compared to 5 %). Capillary Suction Time tests demonstrated a 14-fold reduction in filterability across all arrangements, accompanied by an increase in interfacial tension exceeding 10 %. Statistically significant changes in the UV–Vis spectra indicated alterations in dissolved organic matter humification, aromaticity, and molecular size of colorimetric dissolved organic matter, DNA, and RNA. FTIR analysis revealed characteristic peaks at 1537 cm−1 and 1648 cm−1, signifying microbial cell wall damage. Rheological analysis showed a reduction in apparent viscosity within the low shear stress zone (τ < 5 Pa) and a shift in the yield stress point to lower shear stresses (τ < 0.14 Pa compared to τ = 0.17 Pa for the untreated samples). Pearson’s correlation test revealed strong, statistically significant correlations between cell wall damage (as identified by FTIR) and hydrodynamic conditions in the reactor, while the correlation with radical formation was not statistically significant. This suggests that hydrodynamic forces were the primary drivers of cell wall damage, with potential synergetic effects from radicals.
{"title":"The impact of radicals on physicochemical properties of waste activated sludge during hydrodynamic cavitation treatment","authors":"Marko Blagojevič , Mojca Zupanc , Jurij Gostiša , Blaž Stres , Alenka Šmid , Matevž Dular , Lidija Slemenik Perše , Urška Gradišar Centa , Benjamin Bizjan , Gašper Rak , Uroš Novak , Blaž Likozar , Sabina Kolbl Repinc","doi":"10.1016/j.ultsonch.2025.107291","DOIUrl":"10.1016/j.ultsonch.2025.107291","url":null,"abstract":"<div><div>In this study, laboratory-scale Pinned Disc Rotary Generator of Hydrodynamic Cavitation was used to treat waste-activated sludge with a Total Solids concentration of 0.7 %. Five different rotor–stator arrangements were tested, focusing on waste-activated sludge physicochemical and rheological parameters of industrial relevance: general chemical analysis, rheometry, dewaterability, interfacial tension, UV–Vis and FTIR spectroscopy. Radical formation in all five arrangements was confirmed using salicylic acid dosimetry before sample testing. Three of the arrangements generated twice the radical concentration of the other two and achieved a disintegration degree three times higher (17 % compared to 5 %). Capillary Suction Time tests demonstrated a 14-fold reduction in filterability across all arrangements, accompanied by an increase in interfacial tension exceeding 10 %. Statistically significant changes in the UV–Vis spectra indicated alterations in dissolved organic matter humification, aromaticity, and molecular size of colorimetric dissolved organic matter, DNA, and RNA. FTIR analysis revealed characteristic peaks at 1537 cm<sup>−1</sup> and 1648 cm<sup>−1</sup>, signifying microbial cell wall damage. Rheological analysis showed a reduction in apparent viscosity within the low shear stress zone (<em>τ</em> < 5 Pa) and a shift in the yield stress point to lower shear stresses (<em>τ</em> < 0.14 Pa compared to <em>τ</em> = 0.17 Pa for the untreated samples). Pearson’s correlation test revealed strong, statistically significant correlations between cell wall damage (as identified by FTIR) and hydrodynamic conditions in the reactor, while the correlation with radical formation was not statistically significant. This suggests that hydrodynamic forces were the primary drivers of cell wall damage, with potential synergetic effects from radicals.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"115 ","pages":"Article 107291"},"PeriodicalIF":8.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antibacterial therapy has been extensively applied in medical field to alleviate the severity and mortality of infection. However, it still exists some issues such as drug side effects, limited efficacy and bacterial resistance. Among the alternative therapies, antibacterial sonodynamic therapy (aSDT) has been explored as a promising approach to tackle those crises. It is meaningful to investigate superior strategy to augment the therapeutic efficacy of aSDT. This review summarizes the potential aSDT-based antibacterial mechanisms and comprehensively discusses the prevailing synergistic strategies, such as nanomaterials-based aSDT antibacterial strategy, aSDT + strategy with physical, chemical and biological methods. Moreover, we also reviewed the medical applications of aSDT strategies. Finally, the perspectives on the current challenges that need be resolved in aSDT are proposed. We expect that this review could provide robust support to expedite the clinical applications of aSDT.
{"title":"Emerging synergistic strategies for enhanced antibacterial sonodynamic therapy: Advances and prospects.","authors":"Hengyu Liu, Zhezhu Nan, Chen Zhao, Liang Bai, Linrong Shi, Chenhui He, Daocheng Wu, Mingxi Wan, Yi Feng","doi":"10.1016/j.ultsonch.2025.107288","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107288","url":null,"abstract":"<p><p>Antibacterial therapy has been extensively applied in medical field to alleviate the severity and mortality of infection. However, it still exists some issues such as drug side effects, limited efficacy and bacterial resistance. Among the alternative therapies, antibacterial sonodynamic therapy (aSDT) has been explored as a promising approach to tackle those crises. It is meaningful to investigate superior strategy to augment the therapeutic efficacy of aSDT. This review summarizes the potential aSDT-based antibacterial mechanisms and comprehensively discusses the prevailing synergistic strategies, such as nanomaterials-based aSDT antibacterial strategy, aSDT + strategy with physical, chemical and biological methods. Moreover, we also reviewed the medical applications of aSDT strategies. Finally, the perspectives on the current challenges that need be resolved in aSDT are proposed. We expect that this review could provide robust support to expedite the clinical applications of aSDT.</p>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":" ","pages":"107288"},"PeriodicalIF":8.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Phase-change nanodroplets hold promising potential for theranostic applications in tumor tissue. However, the initial nucleation of nanodroplets in tissue—a critical stage for subsequent vapor bubble dynamics and theranostic efficacy—remains unexplored. This work, accounting for nanodroplets and tissue as compressible mediums, was represented by two springs in series: one for nanodroplet compressibility and the other for tissue elasticity. By analyzing the linear relationship between internal nanodroplet pressure and volume changes in nanodroplets and tissue, the classical nucleation theory (CNT) was modified to describe the initial nucleation of perfluoropentane (PFP) nanodroplets in tissue. The key nucleation conditions, such as the stable critical radius and initial nucleation threshold (INT) were investigated based on the modified CNT. Results revealed that introducing the nanodroplet compressibility and tissue elasticity allows the existence of a stable critical radius—which is more physically meaningful, highlighting their important effects on nucleation. Additionally, the INT increased significantly with the increase in tissue bulk modulus. For example, with an increase in bulk modulus from 0.03 MPa to 0.67 MPa, the INT increased by about 1.1 MPa. The increased behavior was more obvious for smaller nanodroplets in higher bulk modulus. The presence of dissolved gases, increasing nanodroplet surface tension, and decreasing nanodroplet radius and ultrasound frequency reduced the INT. Further analysis of the achievable nucleation area in tissue, which was expanded significantly at lower frequencies. Overall, this study enhances the understanding of initial nanodroplet nucleation in tissue, offering insights into designing and optimizing nanodroplet-based theranostic strategies.
{"title":"Initial nucleation of nanodroplets in viscoelastic tissue driven by ultrasound: A theoretical simulation","authors":"Kangyi Feng, Yueyuan Wang, Chaonan Zhang, Anqi Huang, Mingxi Wan, Yujin Zong","doi":"10.1016/j.ultsonch.2025.107285","DOIUrl":"10.1016/j.ultsonch.2025.107285","url":null,"abstract":"<div><div>Phase-change nanodroplets hold promising potential for theranostic applications in tumor tissue. However, the initial nucleation of nanodroplets in tissue—a critical stage for subsequent vapor bubble dynamics and theranostic efficacy—remains unexplored. This work, accounting for nanodroplets and tissue as compressible mediums, was represented by two springs in series: one for nanodroplet compressibility and the other for tissue elasticity. By analyzing the linear relationship between internal nanodroplet pressure and volume changes in nanodroplets and tissue, the classical nucleation theory (CNT) was modified to describe the initial nucleation of perfluoropentane (PFP) nanodroplets in tissue. The key nucleation conditions, such as the stable critical radius and initial nucleation threshold (INT) were investigated based on the modified CNT. Results revealed that introducing the nanodroplet compressibility and tissue elasticity allows the existence of a stable critical radius—which is more physically meaningful, highlighting their important effects on nucleation. Additionally, the INT increased significantly with the increase in tissue bulk modulus. For example, with an increase in bulk modulus from 0.03 MPa to 0.67 MPa, the INT increased by about 1.1 MPa. The increased behavior was more obvious for smaller nanodroplets in higher bulk modulus. The presence of dissolved gases, increasing nanodroplet surface tension, and decreasing nanodroplet radius and ultrasound frequency reduced the INT. Further analysis of the achievable nucleation area in tissue, which was expanded significantly at lower frequencies. Overall, this study enhances the understanding of initial nanodroplet nucleation in tissue, offering insights into designing and optimizing nanodroplet-based theranostic strategies.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"115 ","pages":"Article 107285"},"PeriodicalIF":8.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143551172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In order to improve the problem of low quality in unwashed surimi gels, this study prepared soybean protein isolate–inulin (SPI–inulin) conjugates using ultrasonic-assisted treatment and investigated their potential applications in unwashed surimi. The results demonstrated that sodium dodecyl sulfate–polyacrylamide gel electrophoresis and fourier transform infrared analysis confirmed the formation of SPI–inulin conjugates. The addition of inulin loosened the structure of SPI. Compared to the unwashed surimi control, the addition of SPI–inulin conjugates significantly improved gel strength, water holding capacity and texture properties (P < 0.05), reduced the free water molecules in the gel matrix, and effectively filled the pores of the surimi gel network when 0.8 % SPI–inulin conjugates were added. In conclusion, the addition of SPI–inulin conjugates represented an effective strategy to enhance the performance of unwashed surimi gels, providing a novel approach for the development of new types of unwashed surimi.
{"title":"Soybean protein isolate–inulin conjugates prepared through ultrasound improves the quality of unwashed surimi gel","authors":"Dongrui Zhang, Jianrong Li, Shumin Yi, Xuepeng Li, Yongxia Xu, Hongbo Mi, Wenhui Zhu","doi":"10.1016/j.ultsonch.2025.107287","DOIUrl":"10.1016/j.ultsonch.2025.107287","url":null,"abstract":"<div><div>In order to improve the problem of low quality in unwashed surimi gels, this study prepared soybean protein isolate–inulin (SPI–inulin) conjugates using ultrasonic-assisted treatment and investigated their potential applications in unwashed surimi. The results demonstrated that sodium dodecyl sulfate–polyacrylamide gel electrophoresis and fourier transform infrared analysis confirmed the formation of SPI–inulin conjugates. The addition of inulin loosened the structure of SPI. Compared to the unwashed surimi control, the addition of SPI–inulin conjugates significantly improved gel strength, water holding capacity and texture properties (<em>P</em> < 0.05), reduced the free water molecules in the gel matrix, and effectively filled the pores of the surimi gel network when 0.8 % SPI–inulin conjugates were added. In conclusion, the addition of SPI–inulin conjugates represented an effective strategy to enhance the performance of unwashed surimi gels, providing a novel approach for the development of new types of unwashed surimi.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"115 ","pages":"Article 107287"},"PeriodicalIF":8.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Curdlan is a microbial extracellular polysaccharide composed of β-(1 → 3)-glycosidic linkages, which exhibits poor water solubility at room temperature due to its formation of crystalline regions through intra- and inter-molecular hydrogen bonding interactions. The chain conformations of curdlan can be modified by different solvents. Thus, this study examined the effects of ultrasonication on the macromolecular, structural, and rheological characteristics of curdlan in three different solvents (0.1 M NaOH, DMSO, and 0.1 M alkali-neutralization (AN)). The results showed that the water solubility of curdlan treated with ultrasonic for 60 min in DMSO, NaOH and AN condition cexhibited 16.26 ± 0.46 %, 13.62 ± 0.23 %, and 15.37 ± 0.61 %, respectively, while their molecular weight values were 10.53 kDa, 19.27 kDa and 17.25 kDa, respectively. This phenomenon indicated that curdlan preferentially dissolved and was susceptible to ultrasonic degradation in DMSO than that in other two solvents, thus enhancing its water solubility. After ultrasonic treatment, the conformation of curdlan in DMSO transformed from flexible chain to irregular helices due to the breaking of both inter- and intra-molecular hydrogen bonds, while there was no significant change in three-helix conformation of curdlan in the other two solvents, implying that curdlan with a flexible chain is more susceptible to degrade by ultrasonic than in rigid rod. Additionally, ultrasonic treatment resulted in decreased rheological properties of curdlan. Overall, this study will offer a theoretical foundation for the ultrasonic modification of curdlan in different solvents, broadening its potential applications in the food industry and biomedicine.
{"title":"Ultrasonic treatment affects the macromolecular, conformational, structural and rheological properties of curdlan in different solvents","authors":"Tong-Xin Liang, Le-Yi Pan, Peiwen Long, Yixin Lin, Long-Qing Li, Ya-Hui Yu, Xiaozhen Liu, Xiangying Yu, Fengyuan Liu, Yuting Li, Ming-Yu Jin, Jing-Kun Yan","doi":"10.1016/j.ultsonch.2025.107289","DOIUrl":"10.1016/j.ultsonch.2025.107289","url":null,"abstract":"<div><div>Curdlan is a microbial extracellular polysaccharide composed of β-(1 → 3)-glycosidic linkages, which exhibits poor water solubility at room temperature due to its formation of crystalline regions through intra- and inter-molecular hydrogen bonding interactions. The chain conformations of curdlan can be modified by different solvents. Thus, this study examined the effects of ultrasonication on the macromolecular, structural, and rheological characteristics of curdlan in three different solvents (0.1 M NaOH, DMSO, and 0.1 M alkali-neutralization (AN)). The results showed that the water solubility of curdlan treated with ultrasonic for 60 min in DMSO, NaOH and AN condition cexhibited 16.26 ± 0.46 %, 13.62 ± 0.23 %, and 15.37 ± 0.61 %, respectively, while their molecular weight values were 10.53 kDa, 19.27 kDa and 17.25 kDa, respectively. This phenomenon indicated that curdlan preferentially dissolved and was susceptible to ultrasonic degradation in DMSO than that in other two solvents, thus enhancing its water solubility. After ultrasonic treatment, the conformation of curdlan in DMSO transformed from flexible chain to irregular helices due to the breaking of both inter- and intra-molecular hydrogen bonds, while there was no significant change in three-helix conformation of curdlan in the other two solvents, implying that curdlan with a flexible chain is more susceptible to degrade by ultrasonic than in rigid rod. Additionally, ultrasonic treatment resulted in decreased rheological properties of curdlan. Overall, this study will offer a theoretical foundation for the ultrasonic modification of curdlan in different solvents, broadening its potential applications in the food industry and biomedicine.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"115 ","pages":"Article 107289"},"PeriodicalIF":8.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-22DOI: 10.1016/j.ultsonch.2025.107283
Yanping Lei , Ye Xu , Peng Meng , Dongkun Tu , Yingting Zhao , Liping Fu , Yuting Tian
In this study, ultrasonic technology was combined with microwave vacuum drying technology to explore the impacts of different coupling methods (ultrasonic pretreatment and ultrasonic coupled drying) on the structural characterisation and physicochemical properties of shiitake mushroom (Lentinus edodes) polysaccharides at different ultrasonic powers (0, 120 and 280 W), and compared with hot air drying (HAD). The results demonstrated that the monosaccharide composition of Lentinus edodes polysaccharides (LEPs) remained largely unaltered after treatment with various drying methods, although significant disparities in molar content were observed. Air ultrasound combined with microwave vacuum drying (USMVD) at 280 W ultrasound power resulted in LEPs with higher contents of total sugars (8.12 ± 0.13 g/100 g), reducing sugars (10.32 ± 0.3 mg/g) and uric acid (2.23 %) compared to those obtained from the HAD treatment. Furthermore, the combination of US280MVD drying treatment of LEPs exhibited a reduction in molecular weight and an enhancement in shear-thinning ability. The results of the study indicate that USMVD is a promising drying treatment technology.
{"title":"Impact of combined ultrasonic and microwave vacuum drying on physicochemical properties and structural characteristics of polysaccharides from shiitake mushrooms (Lentinus edodes)","authors":"Yanping Lei , Ye Xu , Peng Meng , Dongkun Tu , Yingting Zhao , Liping Fu , Yuting Tian","doi":"10.1016/j.ultsonch.2025.107283","DOIUrl":"10.1016/j.ultsonch.2025.107283","url":null,"abstract":"<div><div>In this study, ultrasonic technology was combined with microwave vacuum drying technology to explore the impacts of different coupling methods (ultrasonic pretreatment and ultrasonic coupled drying) on the structural characterisation and physicochemical properties of shiitake mushroom (<em>Lentinus edodes</em>) polysaccharides at different ultrasonic powers (0, 120 and 280 W), and compared with hot air drying (HAD). The results demonstrated that the monosaccharide composition of <em>Lentinus edodes</em> polysaccharides (LEPs) remained largely unaltered after treatment with various drying methods, although significant disparities in molar content were observed. Air ultrasound combined with microwave vacuum drying (USMVD) at 280 W ultrasound power resulted in LEPs with higher contents of total sugars (8.12 ± 0.13 g/100 g), reducing sugars (10.32 ± 0.3 mg/g) and uric acid (2.23 %) compared to those obtained from the HAD treatment. Furthermore, the combination of US280MVD drying treatment of LEPs exhibited a reduction in molecular weight and an enhancement in shear-thinning ability. The results of the study indicate that USMVD is a promising drying treatment technology.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"115 ","pages":"Article 107283"},"PeriodicalIF":8.7,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-22DOI: 10.1016/j.ultsonch.2025.107276
Waseem Khalid , Imed E. Benmebarek , Sina Zargarchi , Prashant Kumar , Miral Javed , Andres Moreno , Aanchal Sharma , Gulzar Ahmad Nayik , Tuba Esatbeyoglu
The chickpea (Cicer arietinum L.) root is an agricultural by-product with the potential for extracting valuable bioactive compounds that often remains underutilized. This study introduces an integrated extraction methodology to enhance the extraction of bioactives using atmospheric air low-pressure cold plasma (CP) treatment followed by ultrasound-assisted extraction (UAE) with natural deep eutectic solvents (NADES). Chickpea root powder was first subjected to CP treatment under optimized conditions (power, pressure, and time) identified via response surface methodology (RSM). Subsequently, UAE-NADES extraction was performed to maximize the results of antioxidant activity (DPPH) and total phenolic content (TPC). The integrated CP-UAE-NADES process enhanced TPC and DPPH compared to the untreated sample (non-CP). The optimum conditions were 11.5 min, 52 W, and 0.65 mbar. The predicted values of the Box-Behnken design for TPC and DPPH were compatible with the experimental Furthermore, microbial load reduction and color stability were analyzed to ensure chickpea root quality and functionality. The combined extraction methodology offers a sustainable and eco-friendly approach for the valorization of chickpea root as a source of bioactives, with potential applications in functional foods, nutraceuticals, and pharmaceuticals.
{"title":"Optimization of the effect of cold plasma treatment on UAE-NADES green extraction of chickpea roots (Cicer arietinum) bioactive compounds","authors":"Waseem Khalid , Imed E. Benmebarek , Sina Zargarchi , Prashant Kumar , Miral Javed , Andres Moreno , Aanchal Sharma , Gulzar Ahmad Nayik , Tuba Esatbeyoglu","doi":"10.1016/j.ultsonch.2025.107276","DOIUrl":"10.1016/j.ultsonch.2025.107276","url":null,"abstract":"<div><div>The chickpea (<em>Cicer arietinum</em> L.) root is an agricultural by-product with the potential for extracting valuable bioactive compounds that often remains underutilized. This study introduces an integrated extraction methodology to enhance the extraction of bioactives using atmospheric air low-pressure cold plasma (CP) treatment followed by ultrasound-assisted extraction (UAE) with natural deep eutectic solvents (NADES). Chickpea root powder was first subjected to CP treatment under optimized conditions (power, pressure, and time) identified via response surface methodology (RSM). Subsequently, UAE-NADES extraction was performed to maximize the results of antioxidant activity (DPPH) and total phenolic content (TPC). The integrated CP-UAE-NADES process enhanced TPC and DPPH compared to the untreated sample (non-CP). The optimum conditions were 11.5 <!--> <!-->min, 52 W, and 0.65 mbar. The predicted values of the Box-Behnken design for TPC and DPPH were compatible with the experimental Furthermore, microbial load reduction and color stability were analyzed to ensure chickpea root quality and functionality. The combined extraction methodology offers a sustainable and eco-friendly approach for the valorization of chickpea root as a source of bioactives, with potential applications in functional foods, nutraceuticals, and pharmaceuticals.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"114 ","pages":"Article 107276"},"PeriodicalIF":8.7,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143471425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-20DOI: 10.1016/j.ultsonch.2025.107275
Fabio Baum , Lars Forberger , Alexander B. Bard , Rachel Gariepy , Peter J. Pauzauskie , Lilo D. Pozzo
The potential of rare earth-doped sodium yttrium fluoride (NaYF4) as upconverting nanoparticles extends to various applications, from electronics to biology. The hexagonal (β) phase of NaYF4 nanoparticles is known to exhibit a photoluminescence quantum yield higher than the cubic (α) phase. The typical synthetic methods for β-NaYF4 present limitations, such as low colloidal stability in aqueous medium and the need for ligand exchange. Herein, we employed high-throughput robotics, automated sonication, and high-throughput X-ray diffraction (HT-XRD) to synthesize and characterize hundreds of samples under various conditions and obtain NaYF4 nanoparticles dispersible in an aqueous medium. We characterized the samples through XRD for phase determination, SEM and TEM for morphology assessment, UV–Vis spectroscopy and zeta potential for colloidal stability evaluation, and photoluminescence spectroscopy and time-resolved photoluminescence spectroscopy to investigate their upconverting properties. We found that only sodium dodecyl sulfate (SDS) promotes β-NaYF4 formation. The order of addition is also important: adding SDS before the precursor salts leads to pure β-NaYF4 formation. Our proposed mechanism for β-NaYF4 formation involves the initial formation of smaller α-NaYF4 crystals in the presence of SDS, which were more easily converted to β-NaYF4 during sonication compared to the larger α-NaYF4 crystals formed in the absence of SDS.
{"title":"Surfactant-assisted phase selective sonochemical synthesis of sodium yttrium fluoride nanoparticles","authors":"Fabio Baum , Lars Forberger , Alexander B. Bard , Rachel Gariepy , Peter J. Pauzauskie , Lilo D. Pozzo","doi":"10.1016/j.ultsonch.2025.107275","DOIUrl":"10.1016/j.ultsonch.2025.107275","url":null,"abstract":"<div><div>The potential of rare earth-doped sodium yttrium fluoride (NaYF<sub>4</sub>) as upconverting nanoparticles extends to various applications, from electronics to biology. The hexagonal (β) phase of NaYF<sub>4</sub> nanoparticles is known to exhibit a photoluminescence quantum yield higher than the cubic (α) phase. The typical synthetic methods for β-NaYF<sub>4</sub> present limitations, such as low colloidal stability in aqueous medium and the need for ligand exchange. Herein, we employed high-throughput robotics, automated sonication, and high-throughput X-ray diffraction (HT-XRD) to synthesize and characterize hundreds of samples under various conditions and obtain NaYF<sub>4</sub> nanoparticles dispersible in an aqueous medium. We characterized the samples through XRD for phase determination, SEM and TEM for morphology assessment, UV–Vis spectroscopy and zeta potential for colloidal stability evaluation, and photoluminescence spectroscopy and time-resolved photoluminescence spectroscopy to investigate their upconverting properties. We found that only sodium dodecyl sulfate (SDS) promotes β-NaYF<sub>4</sub> formation. The order of addition is also important: adding SDS before the precursor salts leads to pure β-NaYF<sub>4</sub> formation. Our proposed mechanism for β-NaYF<sub>4</sub> formation involves the initial formation of smaller α-NaYF<sub>4</sub> crystals in the presence of SDS, which were more easily converted to β-NaYF<sub>4</sub> during sonication compared to the larger α-NaYF<sub>4</sub> crystals formed in the absence of SDS.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"114 ","pages":"Article 107275"},"PeriodicalIF":8.7,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143473605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号