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2006 IEEE International Frequency Control Symposium and Exposition最新文献

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Characterization of Extracellular Matrix (ECM) Produced by MC3T3 Cells Using Thickness Shear Mode (TSM) Resonators 利用厚度剪切模式(TSM)谐振器表征MC3T3细胞产生的细胞外基质(ECM)
Pub Date : 2006-06-01 DOI: 10.1109/FREQ.2006.275443
Fang Li, Qing-Ming Wang, J.H.-C. Wang
Quartz thickness shear mode (TSM) resonators for monitoring the attachment and spreading of mammalian cells have been investigated in the past years. Recent studies have shown that the TSM resonator signal is not only contributed by cellular body closed to the resonator substrate, but also contributed by the extracellular matrix (ECM), which is a protein layer between the cellular body and the resonator surface. Therefore, the quartz TSM resonator is expected to provide a simple, quantitative and effective method to characterize the ECM produced by cells. In this study, we investigate the use of quartz TSM resonators to monitor the ECM production by cells in real time and to characterize the mechanical properties and the thickness of this protein layer. MC3T3-E1 fibroblasts are chosen in our study because they are an established cell line that is stable in culture from passage to passage and they can produce abundant collagenous matrix within a relatively short culture period. AT-cut quartz crystal resonators coated with gold electrodes on both sides are used in this study. An impedance analyzer is used for measuring the admittance spectra and total parallel capacitance of the resonators. Multilayer model is constructed to characterize the mechanical properties and thickness of the ECM layer by using a curve-fitting method. The results obtained by TSM resonator sensors show a good agreement with those obtained by chemical methods
石英厚度剪切模式(TSM)谐振器用于监测哺乳动物细胞的附着和扩散在过去的几年里进行了研究。近年来的研究表明,TSM谐振器信号不仅由靠近谐振器底物的细胞体贡献,还由细胞体与谐振器表面之间的蛋白质层细胞外基质(extracellular matrix, ECM)贡献。因此,石英TSM谐振器有望提供一种简单、定量和有效的方法来表征细胞产生的ECM。在这项研究中,我们研究了使用石英TSM谐振器实时监测细胞产生的ECM,并表征该蛋白质层的力学特性和厚度。我们之所以选择MC3T3-E1成纤维细胞,是因为MC3T3-E1成纤维细胞是一种成熟的细胞系,在传代培养中稳定,在较短的培养时间内可以产生丰富的胶原基质。在本研究中使用了at切割的石英晶体谐振器,其两侧涂有金电极。用阻抗分析仪测量了谐振器的导纳谱和总并联电容。采用曲线拟合的方法,建立了多层模型来表征ECM层的力学性能和厚度。TSM谐振器传感器的测量结果与化学方法的测量结果吻合较好
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引用次数: 2
Energy-Trapping Torsional-Mode Resonators for Liquid Sensing 用于液体传感的能量捕获扭模谐振器
Pub Date : 2006-06-01 DOI: 10.1109/FREQ.2006.275365
M.K. Kang, Rui Huang, T. Knowles
Thickness-shear mode quartz crystal microbalance (QCM) has been widely used as liquid-phase sensors, such as viscometers and bio-detectors. However, due to coupling between the in-plane shear motion and the out-of-plane flexure, when used in contact with or immersed in a liquid, the out-of-plane motion generates compressional waves in the liquid that reflect off the liquid surface and return to the crystal. This interference effect causes depth-sensitive perturbations in the sensor response, often undesirable. In this study, we show that torsional-mode resonators may be used for liquid sensing without the depth effect. Samples in form of stepped plates, circular decals, and convex contoured faces are machined in elastic plates (e.g., cast aluminum, stainless steel, and brass). A non-contact electromagnetic acoustic transducer (EMAT) was employed to drive torsional-mode vibrations. Efficient energy trapping was observed for first-order torsional modes, leading to high quality factors. When placed in contact with water, the resonance frequency of the torsional mode was found to be independent of the water depth, in contrast to depth-dependent frequency oscillation for the thickness-shear mode. Finite element analyses are conducted to understand the torsional-mode vibrations as well as the effect of material anisotropy
厚度-剪切模式石英晶体微天平(QCM)已广泛应用于液相传感器,如粘度计和生物检测器。然而,由于面内剪切运动和面外弯曲之间的耦合,当与液体接触或浸入液体时,面外运动在液体中产生纵波,这些纵波从液体表面反射并返回到晶体中。这种干扰效应在传感器响应中引起深度敏感的扰动,通常是不希望出现的。在这项研究中,我们证明了扭转模谐振器可以用于没有深度效应的液体传感。在阶梯板,圆形贴花和凸轮廓面形式的样品在弹性板(例如,铸铝,不锈钢和黄铜)中加工。采用非接触式电磁声换能器(EMAT)驱动扭振型振动。在一阶扭转模态中观察到有效的能量捕获,从而获得高质量因子。当与水接触时,发现扭转模态的共振频率与水深无关,而厚度-剪切模态的频率振荡则与水深相关。通过有限元分析来了解扭转模态振动以及材料各向异性的影响
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引用次数: 8
Parameters Extraction and Design Optimization for AT-cut Quartz Resonator based on Mindlin's 2D Model 基于Mindlin二维模型的at切割石英谐振器参数提取与设计优化
Pub Date : 2006-06-01 DOI: 10.1109/FREQ.2006.275348
S. Pao, M. Chao, T. Wang, D. Chang, C. S. Lam, P.Z. Chang
For miniaturized strip AT-cut quartz resonator, the demand of performance is higher and higher, so the design ability is more important than before. But to get a precise simulation electrical response of the AT-cut quartz plate by a common commercial FEM tool is not easy and time consuming also. Base on Mindlin's (1961) 2D model and Lee-Brebbia's (1978) FEA method, Pao (2004) et al. presented an efficient numerical method in calculating the electrical response different modes of AT-cut strip quartz crystal resonator with electrode. Base on weak coupling of quartz material and mass loading effect of electrode, this problem was solved by separating the mechanical vibration and electrical coupling effects. The method considers not only the pure mechanical vibration but also the electrical response, so different modes can be identified effectively and efficiently. However, to be a practical design tool, the parameters used in the simulation better come from real samples. In this paper, the works was extended to parameters extraction for design optimization. A blank with electrode was built and its acoustic and electrical material parameters (including damping coefficient) of the quartz resonators could be extracted by fitting to few measured sample admittance curves. The extracted parameters could be used for design optimization purpose. To examine the effectiveness of the parameters extraction, another blank with electrode quartz resonator was built and the results showed the calculated impedance curves could match the measured ones, and a practical AT-cut strip quartz resonator design tool could be made based on extended Mindilin's 2D model
对于小型化的条形at切割石英谐振器,其性能要求越来越高,因此设计能力比以往更加重要。但是,用普通的商用有限元工具精确模拟at切割石英石板的电响应并不容易,而且耗时。Pao(2004)等人在Mindlin(1961)二维模型和Lee-Brebbia(1978)有限元分析方法的基础上,提出了一种计算at切割带电极石英晶体谐振器不同模式电响应的有效数值方法。基于石英材料的弱耦合和电极的质量加载效应,将机械振动和电耦合效应分离,解决了这一问题。该方法不仅考虑了纯机械振动,而且考虑了电响应,因此可以有效地识别不同的模态。然而,为了成为一个实用的设计工具,仿真中使用的参数最好来自真实的样品。本文将工作扩展到设计优化的参数提取。建立了带电极的空白电极,通过拟合少量实测样品的导纳曲线,可以提取石英谐振器的声、电材料参数(包括阻尼系数)。提取的参数可用于设计优化。为了验证参数提取的有效性,建立了另一个电极石英谐振器的空白,结果表明,计算得到的阻抗曲线与实测曲线吻合较好,并基于扩展的Mindilin二维模型构建了实用的at切割条形石英谐振器设计工具
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引用次数: 4
ADEV Calculated from Phase Noise Measurements and Its Possible Errors Due to FFT Sampling 从相位噪声测量计算ADEV及其由于FFT采样可能产生的误差
Pub Date : 2006-06-01 DOI: 10.1109/FREQ.2006.275452
Do-Cheng Chang, Shang-Shian Chen, Shinn-Yan Lin
In this paper, we show that fast Fourier transform (FFT) sampling plays an important role in the calculation of Allan deviation (ADEV) while using the numerical integration as a tool for the time and frequency (T&F) conversion. In order to avoid generation of unreasonable ADEV values, FFT sampling data are re-generated with logarithmic frequency space using an interpolation skill. Therefore, results from both the numerical integration and the power-law processes could match each other quite well. Besides, spurs in spectral density have non-neglectful influences upon ADEV results. For example, when the data of our lab's phase noise measurement system are processed, the ADEV generated from the spectral density with spurs may reach to three times the one while spurs are removed
在本文中,我们证明了快速傅里叶变换(FFT)采样在计算艾伦偏差(ADEV)中起着重要的作用,同时使用数值积分作为时间和频率(T&F)转换的工具。为了避免产生不合理的ADEV值,利用插值技术对对数频率空间重新生成FFT采样数据。因此,数值积分和幂律过程的结果可以很好地吻合。此外,谱密度中的杂散对ADEV结果也有不可忽视的影响。例如,在处理本实验室相位噪声测量系统的数据时,有杂散的谱密度产生的ADEV可以达到去除杂散时的三倍
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引用次数: 0
Modified Lee Plate Equations for the Vibration Analysis of Piezoelectric Plates with Consideration of Stiffness and Mass of Electrodes 考虑电极刚度和质量的压电板振动分析的修正Lee板方程
Pub Date : 2006-06-01 DOI: 10.1109/FREQ.2006.275479
Ji Wang, Guojun Chen, J. Du
Lee plate equations for high frequency vibrations of piezoelectric plates have been established and improved over the decades with the sole objective to obtain the accurate prediction of frequency and mode shapes to aid crystal resonator design. The latest improvement includes extra terms related to derivatives of the flexural displacement to adjust the accuracy and for the consideration of the electrode for practical applications. As part of the efforts to make the equations more practical for resonator design with the improved of frequency accuracy and consideration of electrodes, the authors derived Lee plate equations for electroded plates by changing the integration limits in the dimension reduction procedure to signify the dominant role of the crystal plate. As a result, the equations are modified for the inclusion of the electrode effects. To improve the accuracy in the vicinity of thickness-shear vibration frequency of electroded plates, we modified the density terms in plate equations to reflect the contribution of both electrode stiffness and density, which makes the frequency more accurate for commonly used electrode materials
几十年来,人们建立并改进了用于压电片高频振动的李氏板方程,其唯一目的是准确预测频率和模态振型,以辅助晶体谐振器的设计。最新的改进包括与弯曲位移导数有关的额外条款,以调整精度和考虑电极的实际应用。由于频率精度的提高和电极的考虑,为了使方程更适用于谐振器设计,作者通过改变降维过程中的积分极限来表示晶体板的主导作用,推导出了电极板的李氏板方程。结果,方程被修正为包含电极效应。为了提高极板厚度-剪切振动频率附近的精度,我们修改了极板方程中的密度项,以反映电极刚度和密度的贡献,从而使常用电极材料的频率更加准确
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引用次数: 1
The Properties of Time and Phase Variances in the Presence of Power Law Noise for Various Systems 各种系统在幂律噪声存在下的时间和相位变化特性
Pub Date : 2006-06-01 DOI: 10.1109/FREQ.2006.275482
V. Reinhardt
This paper discusses the behavior of sample, standard, bandpass, and Allan variances of the time and phase error in the presence of negative power law or fbeta noise for a variety of systems. These systems include those in the digital, communications, signal processing, radar, ranging, and time transfer areas. A theory is presented which spectrally defines these variances by explicitly incorporating a system phase response function Hs(f) into the spectral integral. For many of the above systems, Hs(f) is shown to contain highpass as well as lowpass filtering properties, and these highpass properties, when present, are shown to enable both the sample and standard variances, as well as Allan variances, to be used in the presence of fbeta noise for beta>-4. It is also shown that the sample variance defined in this way can be used to justify the heuristic low and high frequency cut-offs that appear in the spectral definition of the bandpass variance (also known as the jitter). Hs(f) is further shown to fall into four general classes for the purposes of characterizing variance behavior. These classes we call: digital sampling, delay, delay with averaging, and PLL. The final part of the paper consists of a detailed discussion of the properties of these variances in the presence of negative power law noise for the above systems, organized by class of Hs(f)
本文讨论了各种系统在存在负幂律或f噪声的情况下,时间和相位误差的样本、标准、带通和艾伦方差的行为。这些系统包括数字、通信、信号处理、雷达、测距和时间传输领域的系统。提出了一种理论,该理论通过显式地将系统相位响应函数Hs(f)合并到谱积分中来光谱地定义这些方差。对于上述许多系统,Hs(f)显示包含高通和低通滤波特性,当这些高通特性存在时,显示使样本和标准方差以及艾伦方差能够在β >-4的fbeta噪声存在时使用。还表明,以这种方式定义的样本方差可以用来证明在带通方差(也称为抖动)的频谱定义中出现的启发式低频和高频截止。为了描述方差行为的特征,进一步表明Hs(f)可分为四类。这些类我们称之为:数字采样、延迟、平均延迟和锁相环。本文的最后一部分包括对上述系统在负幂律噪声存在下的这些方差的性质的详细讨论,按Hs(f)类组织。
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引用次数: 5
Development of an Optical Lattice Clock in NMIJ, AIST AIST NMIJ光学点阵时钟的研制
Pub Date : 2006-06-01 DOI: 10.1109/FREQ.2006.275397
M. Yasuda, F. Hong, T. Kurosu, T. Kohno, J. Ishikawa, A. Onae, S. Ohshima, H. Katori
A development plan and the present status of the optical lattice clock in NMIJ, especially the details of the vacuum system and the laser sources, are described
介绍了NMIJ光学晶格钟的发展计划和现状,特别是真空系统和激光源的细节
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引用次数: 1
Study of an Optimal Algorithm for Combing TWSTFT and GPS CV Comparisons TWSTFT与GPS CV比较的最优算法研究
Pub Date : 2006-06-01 DOI: 10.1109/FREQ.2006.275463
Li Gun, Huang Hui, Zhong Chong-xia, Zhou Wei
Two-way satellite time and frequency transfer (TWSTFT) and GPS C/A code based common view (GPS CV) are the two primary methods for international time and frequency transfer. TWSTFT technique has been made significant improvement in the last several years, and demonstrated to show a higher precision of T&F transfer than that of GPS CV. So it has been utilized for in the computation of TAI (international atomic time) and the GPS CV link is regarded as a back up if the links have both TWSTFT and GPS CV time transfer links. Actually, the TWSTFT is unavailable frequently for some unknown reasons or failure of instrument. More important, in some links, the comparison result of GPS CV has valuable information in the calculation of TAI and UTC (coordinated universal time). Considering these two cases, we have been used GPS CV C/A code and TWSTFT observations in attempt to form a more stable and reliable composite time transfer links. In this study we have focused on the unavailability when the system has malfunction or abnormality, in this case, the GPS CV data will be used in TAI computation which will cause a systematic error that should be deduct in some links. Finally, to avoid the above mentioned shortcomings, a new optimal algorithm for combining the two types time transfer data is given, the details of the optimal algorithm has been presented in this paper. A more stable and reliable time comparison result has been achieved in time comparison between some national time laboratories. The UTC(USNO)-UTC(PTB) and the UTC(ROA)-UTC(PTB) are given as a example
双向卫星时频传输(TWSTFT)和基于GPS C/A码的共视(GPS CV)是国际时频传输的两种主要方法。TWSTFT技术在过去几年中取得了显著的进步,并被证明具有比GPS CV更高的T&F传输精度。因此,在计算TAI(国际原子时)时中,如果GPS CV链路同时具有TWSTFT和GPS CV时传递链路,则将其视为备份链路。实际上,由于一些未知的原因或仪器故障,TWSTFT经常不可用。更重要的是,在某些环节,GPS CV的比较结果对TAI和协调世界时(UTC)的计算具有重要的参考价值。考虑到这两种情况,我们使用了GPS CV C/A码和TWSTFT观测值,试图形成一个更稳定可靠的复合时间传递链路。在本研究中,我们关注的是当系统发生故障或异常时的不可用性,在这种情况下,GPS CV数据将用于TAI计算,这将导致系统误差,在某些环节需要扣除。最后,为了避免上述缺点,提出了一种新的结合两种时间传递数据的优化算法,并给出了优化算法的具体细节。在一些国家级时间实验室的时间比对中,取得了较为稳定可靠的时间比对结果。以UTC(USNO)-UTC(PTB)和UTC(ROA)-UTC(PTB)为例
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引用次数: 1
A New Algorithm of Detecting and Correction Cycle Slips in Dual-Frequency GPS 一种新的双频GPS周期跳检测与校正算法
Pub Date : 2006-06-01 DOI: 10.1109/FREQ.2006.275459
Li Gun, Hu Yong-hui, Zhou Wei
Detecting and reconstructing the cycle slip are very important in GPS carrier phase time transfer (GPS CPTT). Many kinds of algorithms have been developed in the past several years especially using GIPSY OASIS software developed by JPL (Jet Propulsion Laboratory) for estimating ambiguity resolution and solving cycle slip problem. NTSC has installed one geodetic like dual frequency Ashtech Z12T receiver for GPS CPTT investigation. The GPS carrier phase time transfer data have been obtained using this receiver at NTSC (National time service center, Chinese Academy of Sciences). In this paper, a new algorithm of TWO STEP method for detecting outliers and cycle slips in dual-frequency GPS is presented. Firstly, using Kalman filter in the model of the 3rd order polynomial for a larger cycle slips, such as larger than 2cycles. Secondly, estimating and reconstruction small cycle slips(less than 1) by using Daubechies wavelet. The details of algorithm are given. The processing result using the algorithm is presented. It is applicable to the carrier phase measurement with one sample per 30 second. The calculated results using data of GPS on NTSC show that the algorithm is so efficiency that it can accurately find the small cycle slip less than one cycle
在GPS载波相位时传递(GPS CPTT)中,周跳的检测和重构是非常重要的。近年来,人们开发了多种算法,特别是利用喷气推进实验室(JPL)开发的GIPSY OASIS软件来估计模糊度分辨率和求解周期滑动问题。NTSC为GPS CPTT调查安装了一台像大地测量仪一样的双频Ashtech Z12T接收机。利用该接收机在中国科学院国家授时中心获得了GPS载波相位时传输数据。本文提出了一种双频GPS异常点和周跳检测的新算法——TWO STEP法。首先,在模型中使用卡尔曼滤波的三阶多项式来处理较大的周跳,如大于2个周期。其次,利用Daubechies小波估计和重建小于1的小周跳。给出了具体的算法。给出了该算法的处理结果。适用于每30秒一个样品的载波相位测量。利用NTSC上的GPS数据计算结果表明,该算法能够准确地找到小于1个周期的小周差,具有很高的效率
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引用次数: 6
Bandwidth Improvement Methods In Acoustically-Coupled Thin Film BAW Devices 声耦合薄膜BAW器件的带宽改进方法
Pub Date : 2006-06-01 DOI: 10.1109/FREQ.2006.275371
V. Kulkarni, K. Prasad, B. Barber
In this paper, the results of a stacked crystal filter (SCF) are presented. It is shown that the bandwidth of the SCF can be designed by choice of electrode materials, device dimensions and use of external components such as inductors. This paper also discusses the fabrication of SCF along with the device layouts. A single stage and a two-stage SCF are designed and it is shown that the bandwidth of two-stage can only be increased if the inductor is connected between stages
本文介绍了一种叠晶滤波器(SCF)的结果。结果表明,SCF的带宽可以通过选择电极材料、器件尺寸和使用电感等外部元件来设计。本文还讨论了SCF的制作和器件布局。设计了单级和两级流场,结果表明,只有在两级之间连接电感器才能增加两级流场的带宽
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引用次数: 4
期刊
2006 IEEE International Frequency Control Symposium and Exposition
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