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Localizing Optic Disc in Retinal Image Automatically with Entropy Based Algorithm. 基于熵的视网膜图像视盘自动定位算法。
IF 7.6 Q2 ENGINEERING, BIOMEDICAL Pub Date : 2018-02-06 eCollection Date: 2018-01-01 DOI: 10.1155/2018/2815163
Lamia AbedNoor Muhammed

Examining retinal image continuously plays an important role in determining human eye health; with any variation present in this image, it may be resulting from some disease. Therefore, there is a need for computer-aided scanning for retinal image to perform this task automatically and accurately. The fundamental step in this task is identification of the retina elements; optical disk localization is the most important one in this identification. Different optical disc localization algorithms have been suggested, such as an algorithm that would be proposed in this paper. The assumption is based on the fact that optical disc area has rich information, so its entropy value is more significant in this area. The suggested algorithm has recursive steps for testing the entropy of different patches in image; sliding window technique is used to get these patches in a specific way. The results of practical work were obtained using different common data set, which achieved good accuracy in trivial computation time. Finally, this paper consists of four sections: a section for introduction containing the related works, a section for methodology and material, a section for practical work with results, and a section for conclusion.

连续检查视网膜图像在判断人眼健康状况中起着重要作用;如果图像中出现任何变化,则可能是由某种疾病引起的。因此,需要计算机辅助视网膜图像扫描来自动准确地完成这一任务。这项任务的基本步骤是识别视网膜元素;光盘定位是其中最重要的一项。不同的光盘定位算法已经被提出,例如本文将提出的一种算法。该假设是基于光盘区域具有丰富的信息,因此其熵值在该区域更为显著。该算法采用递归步骤测试图像中不同斑块的熵;使用滑动窗口技术以特定的方式获得这些补丁。利用不同的常用数据集,得到了实际工作的结果,在较小的计算时间内取得了较好的精度。最后,本文由四个部分组成:绪论部分包含相关著作,方法论和材料部分,实际工作和结果部分,结论部分。
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引用次数: 18
Respiratory Motion Correction for Compressively Sampled Free Breathing Cardiac MRI Using Smooth l1-Norm Approximation. 使用平滑 l1-正则近似对压缩采样的自由呼吸心脏磁共振成像进行呼吸运动校正
IF 7.6 Q2 ENGINEERING, BIOMEDICAL Pub Date : 2018-01-23 eCollection Date: 2018-01-01 DOI: 10.1155/2018/7803067
Muhammad Bilal, Jawad Ali Shah, Ijaz M Qureshi, Kushsairy Kadir

Transformed domain sparsity of Magnetic Resonance Imaging (MRI) has recently been used to reduce the acquisition time in conjunction with compressed sensing (CS) theory. Respiratory motion during MR scan results in strong blurring and ghosting artifacts in recovered MR images. To improve the quality of the recovered images, motion needs to be estimated and corrected. In this article, a two-step approach is proposed for the recovery of cardiac MR images in the presence of free breathing motion. In the first step, compressively sampled MR images are recovered by solving an optimization problem using gradient descent algorithm. The L1-norm based regularizer, used in optimization problem, is approximated by a hyperbolic tangent function. In the second step, a block matching algorithm, known as Adaptive Rood Pattern Search (ARPS), is exploited to estimate and correct respiratory motion among the recovered images. The framework is tested for free breathing simulated and in vivo 2D cardiac cine MRI data. Simulation results show improved structural similarity index (SSIM), peak signal-to-noise ratio (PSNR), and mean square error (MSE) with different acceleration factors for the proposed method. Experimental results also provide a comparison between k-t FOCUSS with MEMC and the proposed method.

最近,磁共振成像(MRI)的变换域稀疏性与压缩传感(CS)理论相结合,被用于缩短采集时间。磁共振扫描过程中的呼吸运动会导致恢复的磁共振图像出现强烈的模糊和重影伪影。为了提高恢复图像的质量,需要对运动进行估计和校正。本文提出了一种分两步恢复存在自由呼吸运动的心脏磁共振图像的方法。第一步,使用梯度下降算法解决优化问题,恢复压缩采样的磁共振图像。优化问题中使用的基于 L1 准则的正则化器由双曲正切函数近似。第二步,利用称为自适应鲁德模式搜索(ARPS)的块匹配算法来估计和纠正恢复图像中的呼吸运动。该框架针对自由呼吸模拟和活体二维心脏椎体磁共振成像数据进行了测试。仿真结果表明,所提方法在不同加速因子下的结构相似性指数(SSIM)、峰值信噪比(PSNR)和均方误差(MSE)都有所改善。实验结果还提供了 k-t FOCUSS 与 MEMC 和建议方法之间的比较。
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引用次数: 0
Narrow-Energy-Width CT Based on Multivoltage X-Ray Image Decomposition. 基于多电压x射线图像分解的窄能宽CT。
IF 7.6 Q2 ENGINEERING, BIOMEDICAL Pub Date : 2017-01-01 Epub Date: 2017-11-07 DOI: 10.1155/2017/8126019
Jiaotong Wei, Yan Han, Ping Chen

A polychromatic X-ray beam causes the grey of the reconstructed image to depend on its position within a solid and the material being imaged. This factor makes quantitative measurements via computed tomography (CT) imaging very difficult. To obtain a narrow-energy-width reconstructed image, we propose a model to decompose multivoltage X-ray images into many narrow-energy-width X-ray images by utilizing the low frequency characteristics of X-ray scattering. It needs no change of hardware in the typical CT system. Solving the decomposition model, narrow-energy-width projections are obtained and it is used to reconstruct the image. A cylinder composed of aluminum and silicon is used in a verification experiment. Some of the reconstructed images could be regarded as real narrow-energy-width reconstructed images, which demonstrates the effectiveness of the proposed method.

多色x射线束使重建图像的灰度取决于其在固体和被成像材料中的位置。这个因素使得通过计算机断层扫描(CT)成像进行定量测量非常困难。为了获得窄能宽重构图像,我们提出了一种利用x射线散射的低频特性将多电压x射线图像分解成多个窄能宽x射线图像的模型。在典型的CT系统中不需要改变硬件。对分解模型进行求解,得到窄能量宽度投影,用于图像重构。在验证实验中,采用了由铝和硅组成的圆筒。部分重构图像可以看作是真实的窄能宽重构图像,验证了所提方法的有效性。
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引用次数: 3
Corrigendum to "Automated Feature Extraction in Brain Tumor by Magnetic Resonance Imaging Using Gaussian Mixture Models". “使用高斯混合模型的磁共振成像在脑肿瘤中的自动特征提取”的更正。
IF 7.6 Q2 ENGINEERING, BIOMEDICAL Pub Date : 2017-01-01 Epub Date: 2017-08-13 DOI: 10.1155/2017/3247974
Ahmad Chaddad, Markus Luedi, Pascal O Zinn, Rivka Colen

[This corrects the article DOI: 10.1155/2015/868031.].

[这更正了文章DOI: 10.1155/2015/868031.]。
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引用次数: 1
An Automatic Gastrointestinal Polyp Detection System in Video Endoscopy Using Fusion of Color Wavelet and Convolutional Neural Network Features. 基于彩色小波与卷积神经网络特征融合的视频内镜胃肠道息肉自动检测系统。
IF 7.6 Q2 ENGINEERING, BIOMEDICAL Pub Date : 2017-01-01 Epub Date: 2017-08-14 DOI: 10.1155/2017/9545920
Mustain Billah, Sajjad Waheed, Mohammad Motiur Rahman

Gastrointestinal polyps are considered to be the precursors of cancer development in most of the cases. Therefore, early detection and removal of polyps can reduce the possibility of cancer. Video endoscopy is the most used diagnostic modality for gastrointestinal polyps. But, because it is an operator dependent procedure, several human factors can lead to misdetection of polyps. Computer aided polyp detection can reduce polyp miss detection rate and assists doctors in finding the most important regions to pay attention to. In this paper, an automatic system has been proposed as a support to gastrointestinal polyp detection. This system captures the video streams from endoscopic video and, in the output, it shows the identified polyps. Color wavelet (CW) features and convolutional neural network (CNN) features of video frames are extracted and combined together which are used to train a linear support vector machine (SVM). Evaluations on standard public databases show that the proposed system outperforms the state-of-the-art methods, gaining accuracy of 98.65%, sensitivity of 98.79%, and specificity of 98.52%.

在大多数情况下,胃肠道息肉被认为是癌症发展的前兆。因此,及早发现并切除息肉可降低癌变的可能性。视频内镜是胃肠道息肉最常用的诊断方法。但是,由于这是一个依赖于操作人员的过程,一些人为因素可能导致息肉的误诊。计算机辅助息肉检测可以降低息肉漏检率,帮助医生找到最需要注意的区域。本文提出了一种支持胃肠道息肉检测的自动系统。该系统从内窥镜视频中捕获视频流,并在输出中显示已识别的息肉。提取视频帧的彩色小波(CW)特征和卷积神经网络(CNN)特征并组合在一起,用于训练线性支持向量机(SVM)。对标准公共数据库的评估表明,该系统优于现有的方法,准确率为98.65%,灵敏度为98.79%,特异性为98.52%。
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引用次数: 83
Saliency-Based Bleeding Localization for Wireless Capsule Endoscopy Diagnosis. 基于显著性的无线胶囊内窥镜出血定位诊断。
IF 7.6 Q2 ENGINEERING, BIOMEDICAL Pub Date : 2017-01-01 Epub Date: 2017-11-28 DOI: 10.1155/2017/8147632
Hongda Chen, Shaoze Wang, Yong Ding, Dahong Qian

Stomach bleeding is a kind of gastrointestinal disease which can be diagnosed noninvasively by wireless capsule endoscopy (WCE). However, it requires much time for physicians to scan large amount of WCE images. Alternatively, computer-assisted bleeding localization systems are developed where color, edge, and intensity features are defined to distinguish lesions from normal tissues. This paper proposes a saliency-based localization system where three saliency maps are computed: phase congruency-based edge saliency map derived from Log-Gabor filter bands, intensity histogram-guided intensity saliency map, and red proportion-based saliency map. Fusing the three maps together, the proposed system can detect bleeding regions by thresholding the fused saliency map. Results demonstrate the accuracy of 98.97% for our system to mark bleeding regions.

胃出血是一种可以通过无线胶囊内镜(WCE)进行无创诊断的胃肠道疾病。然而,对于医生来说,扫描大量的WCE图像需要花费大量的时间。另外,计算机辅助的出血定位系统被开发出来,其中定义了颜色、边缘和强度特征,以区分病变和正常组织。本文提出了一种基于显著性的定位系统,该系统计算了三个显著性图:基于相位一致性的Log-Gabor滤波带边缘显著性图、基于强度直方图的强度显著性图和基于红色比例的显著性图。该系统将三幅图像融合在一起,通过对融合后的显著性图像进行阈值处理,检测出出血区域。结果表明,该系统标记出血区域的准确率为98.97%。
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引用次数: 4
Sparse Codebook Model of Local Structures for Retrieval of Focal Liver Lesions Using Multiphase Medical Images. 基于稀疏码本模型的多相医学图像局部结构检索。
IF 7.6 Q2 ENGINEERING, BIOMEDICAL Pub Date : 2017-01-01 Epub Date: 2017-02-13 DOI: 10.1155/2017/1413297
Jian Wang, Xian-Hua Han, Yingying Xu, Lanfen Lin, Hongjie Hu, Chongwu Jin, Yen-Wei Chen

Characterization and individual trait analysis of the focal liver lesions (FLL) is a challenging task in medical image processing and clinical site. The character analysis of a unconfirmed FLL case would be expected to benefit greatly from the accumulated FLL cases with experts' analysis, which can be achieved by content-based medical image retrieval (CBMIR). CBMIR mainly includes discriminated feature extraction and similarity calculation procedures. Bag-of-Visual-Words (BoVW) (codebook-based model) has been proven to be effective for different classification and retrieval tasks. This study investigates an improved codebook model for the fined-grained medical image representation with the following three advantages: (1) instead of SIFT, we exploit the local patch (structure) as the local descriptor, which can retain all detailed information and is more suitable for the fine-grained medical image applications; (2) in order to more accurately approximate any local descriptor in coding procedure, the sparse coding method, instead of K-means algorithm, is employed for codebook learning and coded vector calculation; (3) we evaluate retrieval performance of focal liver lesions (FLL) using multiphase computed tomography (CT) scans, in which the proposed codebook model is separately learned for each phase. The effectiveness of the proposed method is confirmed by our experiments on FLL retrieval.

局灶性肝病变(FLL)的特征和个体特征分析是医学图像处理和临床现场的一项具有挑战性的任务。基于内容的医学图像检索(CBMIR)技术可以通过积累的FLL病例和专家的分析,对未确诊的FLL病例进行特征分析。CBMIR主要包括判别特征提取和相似度计算两个步骤。视觉词袋(BoVW)(基于码本的模型)已被证明对不同的分类和检索任务是有效的。本文研究了一种改进的细粒度医学图像表示码本模型,该模型具有以下三个优点:(1)利用局部斑块(结构)作为局部描述子,可以保留所有的详细信息,更适合于细粒度医学图像的应用;(2)为了在编码过程中更准确地逼近任意局部描述符,采用稀疏编码方法代替K-means算法进行码本学习和编码向量计算;(3)我们使用多相计算机断层扫描(CT)评估局灶性肝脏病变(FLL)的检索性能,其中所提出的代码本模型在每个阶段分别学习。本文的FLL检索实验验证了该方法的有效性。
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引用次数: 26
Future of the Renal Biopsy: Time to Change the Conventional Modality Using Nanotechnology. 肾活检的未来:利用纳米技术改变传统检查方式的时候到了。
IF 7.6 Q2 ENGINEERING, BIOMEDICAL Pub Date : 2017-01-01 Epub Date: 2017-02-19 DOI: 10.1155/2017/6141734
Hamid Tayebi Khosroshahi, Behzad Abedi, Sabalan Daneshvar, Yashar Sarbaz, Abolhassan Shakeri Bavil

At the present time, imaging guided renal biopsy is used to provide diagnoses in most types of primary and secondary renal diseases. It has been claimed that renal biopsy can provide a link between diagnosis of renal disease and its pathological conditions. However, sometimes there is a considerable mismatch between patient renal outcome and pathological findings in renal biopsy. This is the time to address some new diagnostic methods to resolve the insufficiency of conventional percutaneous guided renal biopsy. Nanotechnology is still in its infancy in renal imaging; however, it seems that it is the next step in renal biopsy, providing solutions to the limitations of conventional modalities.

目前,成像引导下的肾活检可用于诊断大多数类型的原发性和继发性肾脏疾病。有人声称,肾活检可以将肾脏疾病的诊断与病理情况联系起来。然而,有时患者的肾病结果与肾活检的病理结果之间存在相当大的不匹配。此时,我们需要一些新的诊断方法来解决传统经皮引导肾活检的不足。纳米技术在肾脏成像方面仍处于起步阶段,但它似乎是肾脏活检的下一步,为解决传统模式的局限性提供了解决方案。
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引用次数: 0
Evaluation of Deformable Image Registration for Three-Dimensional Temporal Subtraction of Chest Computed Tomography Images. 可变形图像配准对胸部ct图像三维时间相减的评价。
IF 7.6 Q2 ENGINEERING, BIOMEDICAL Pub Date : 2017-01-01 Epub Date: 2017-10-12 DOI: 10.1155/2017/3457189
Ping Yan, Yoshie Kodera, Kazuhiro Shimamoto

Purpose: To perform lung image registration for reducing misregistration artifacts on three-dimensional (3D) temporal subtraction of chest computed tomography (CT) images, in order to enhance temporal changes in lung lesions and evaluate these changes after deformable image registration (DIR).

Methods: In 10 cases, mutual information (MI) lung mask affine mapping combined with cross-correlation (CC) lung diffeomorphic mapping was used to implement lung volume registration. With advanced normalization tools (ANTs), we used greedy symmetric normalization (greedy SyN) as a transformation model, which involved MI-CC-SyN implementation. The resulting displacement fields were applied to warp the previous (moving) image, which was subsequently subtracted from the current (fixed) image to obtain the lung subtraction image.

Results: The average minimum and maximum log-Jacobians were 0.31 and 3.74, respectively. When considering 3D landmark distance, the root-mean-square error changed from an average of 20.82 mm for Pfixed to Pmoving to 0.5 mm for Pwarped to Pfixed. Clear shadows were observed as enhanced lung nodules and lesions in subtraction images. The lesion shadows showed lesion shrinkage changes over time. Lesion tissue morphology was maintained after DIR.

Conclusions: DIR (greedy SyN) effectively and accurately enhanced temporal changes in chest CT images and decreased misregistration artifacts in temporal subtraction images.

目的:对肺部图像进行配准,以减少胸部计算机断层扫描(CT)图像三维(3D)时间减影上的错配伪影,从而增强肺部病变的时间变化,并评估形变图像配准(DIR)后的这些变化。方法:对10例患者采用互信息(MI)肺掩膜仿射成像结合互相关(CC)肺差胚成像进行肺容积配准。使用高级规范化工具(ant),我们使用贪婪对称规范化(贪心SyN)作为转换模型,其中涉及MI-CC-SyN实现。由此产生的位移场被应用于扭曲前一个(移动)图像,随后从当前(固定)图像中减去该图像,得到肺减法图像。结果:平均最小和最大对数雅可比矩阵分别为0.31和3.74。当考虑三维地标距离时,均方根误差从Pfixed到Pmoving的平均20.82 mm变为Pwarped到Pfixed的平均0.5 mm。减影图像中可见肺结节和病变增强的清晰阴影。病灶阴影显示病灶缩小随时间变化。术后保持病变组织形态。结论:DIR(贪心SyN)有效、准确地增强了胸部CT图像的时间变化,减少了时间减影图像的错配伪影。
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引用次数: 3
A Multitasking Electrical Impedance Tomography System Using Titanium Alloy Electrode. 钛合金电极多任务电阻抗层析成像系统。
IF 7.6 Q2 ENGINEERING, BIOMEDICAL Pub Date : 2017-01-01 Epub Date: 2017-10-31 DOI: 10.1155/2017/3589324
Abdalla Salama, Amin Malekmohammadi, Shahram Mohanna, Rajprasad Rajkumar

This paper presents a multitasking electrical impedance tomography (EIT) system designed to improve the flexibility and durability of an existing EIT system. The ability of the present EIT system to detect, locate, and reshape objects was evaluated by four different experiments. The results of the study show that the system can detect and locate an object with a diameter as small as 1.5 mm in a testing tank with a diameter of 134 mm. Moreover, the results demonstrate the ability of the current system to reconstruct an image of several dielectric object shapes. Based on the results of the experiments, the programmable EIT system can adapt the EIT system for different applications without the need to implement a new EIT system, which may help to save time and cost. The setup for all the experiments consisted of a testing tank with an attached 16-electrode array made of titanium alloy grade 2. The titanium alloy electrode was used to enhance EIT system's durability and lifespan.

本文提出了一种多任务电阻抗断层成像(EIT)系统,旨在提高现有EIT系统的灵活性和耐用性。通过四种不同的实验来评估当前EIT系统检测、定位和重塑目标的能力。研究结果表明,该系统可以在直径为134 mm的测试槽中检测和定位直径小至1.5 mm的物体。此外,实验结果还证明了当前系统重建多种介质物体形状图像的能力。实验结果表明,该可编程EIT系统可以适应不同的应用,而不需要重新设计EIT系统,这有助于节省时间和成本。所有实验的设置都由一个测试槽组成,该测试槽附有由2级钛合金制成的16个电极阵列。采用钛合金电极,提高了EIT系统的耐用性和寿命。
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引用次数: 2
期刊
International Journal of Biomedical Imaging
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