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The impact of CENTION-N compared to glass-ionomer cement on shear bond strength and micro-leakage of primary teeth restorations: a systematic review and meta-analysis. 与玻璃离子水门汀相比,CENTION-N对乳牙修复体剪切粘结强度和微渗漏的影响:一项系统综述和荟萃分析。
IF 2.3 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-19 DOI: 10.1007/s44445-025-00049-4
Narjes Amrollahi, Monireh Sadeghi, Atiyeh Feiz, Mohammad Javad Tarrahi

One of the main goals in pediatric dentistry is to perform effective treatments with minimal intervention and in the shortest possible time. New restorative materials for primary teeth, such as Cention-N, may overcome the mechanical limitations of Glass-Ionomer Cement (GIC). This study systematically reviews the shear bond strength (SBS) and micro-leakage of GIC and Cention-N in primary teeth. This research was conducted as a systematic review and meta-analysis. Comprehensive searches were carried out in reputable databases including Embase, PubMed, Scopus, Web of Science, and Cochrane up to December 2024. Relevant in vitro studies that met the inclusion criteria were selected and assessed using the QUIN checklist. Data were analyzed with CMA software. The I2 test evaluated heterogeneity, and the Begg test detected publication bias. Out of 179 articles identified, 12 met the inclusion criteria and were included in the study. Ten of these were eligible for meta-analysis. The results showed that the SBS of Cention-N was significantly higher than that of GIC when bonding agents were used (Standardized Mean Difference [SMD]: 5.61; 95% CI: -6.99 to -4.23; P < 0.001). Additionally, micro-leakage of Cention-N was significantly lower compared to GIC under the same conditions (SMD: 1.7; 95% CI: 0.85 to 2.54; P < 0.001). Cention-N, with its superior mechanical properties and reduced micro-leakage when bonding agents were used, appears to be a promising option for primary tooth restorations, especially in stress-bearing areas.

儿童牙科的主要目标之一是在最短的时间内以最少的干预进行有效的治疗。新型乳牙修复材料,如Cention-N,可能克服玻璃离子水门汀(GIC)的机械局限性。本研究系统地综述了GIC和Cention-N在乳牙中的剪切粘结强度(SBS)和微泄漏。本研究采用系统综述和荟萃分析的方式进行。全面的搜索在知名数据库中进行,包括Embase, PubMed, Scopus, Web of Science和Cochrane,截止到2024年12月。选择符合纳入标准的相关体外研究,并使用QUIN检查表进行评估。采用CMA软件对数据进行分析。I2检验评估异质性,Begg检验检测发表偏倚。在鉴定的179篇文章中,有12篇符合纳入标准,被纳入本研究。其中10个符合荟萃分析的条件。结果表明,使用黏合剂时,Cention-N的SBS明显高于GIC(标准化平均差[SMD]: 5.61; 95% CI: -6.99 ~ -4.23
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引用次数: 0
Evaluation of the Effect of Saudi Coffee Consumption in Comparison to Various Types of Coffees on the Color of Novel Aesthetic Dental Ceramics. 沙特咖啡消费量与不同类型咖啡对新型美学牙科陶瓷颜色的影响评价
IF 2.3 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-13 DOI: 10.1007/s44445-025-00047-6
Ghada O Alrabeah, Abdullatif A AlGhazzi, Naif H AlOtaibi, Ali N AlAnzan, Khalid F AlOtaibi

The aim of this study was to evaluate the effect of Saudi coffee consumption in comparison to various types of commonly used coffees (instant black, Turkish, and espresso) on the color of novel aesthetic dental ceramics. A total of 144 flat cylindrical discs with an 8-mm diameter and 0.5-mm thickness were created using CAD/CAM technology. Three ceramic materials were used: Lithium disilicate (Emax) and two ultra-translucent monolithic zirconia ceramics; Aidite and Cercon Xt (Cer). The specimens were immersed in six coffee solutions: Saudi coffee from eastern region (ES), Saudi coffee from northern region (SN), Saudi coffee from middle region (SM), instant black coffee (Ne), Turkish coffee (Tk) and espresso coffee (Es). All specimens (n = 8) were immersed for a period of 15 days. The color of all specimens was measured before and after immersion, and the CIE L*a* b* coordinates were obtained with a spectrophotometer. Values for the translucency parameter (TP), contrast ratio (CR) and color change (ΔE) for each specimen were calculated. Data were analyzed using paired sample t-test and one-way ANOVA and post hoc testing. Color coordinates L*, a* and b* significantly changed after immersion in all coffee solutions relative to pre-immersion values, with a noticeable decrease in lightness (L*) (P < .05). A significant color change (∆E) was observed in all tested materials in all coffee solutions after immersion, with ∆E values exceeding 5.26 (P < 0.05). Color changes (∆E) for specimens immersed in the three formulations of Saudi coffee were significantly less than those immersed in the other coffee solutions (P < 0.05). Saudi coffee with formulations from the northern region resulted in more color changes in Emax in comparisons to the other two Saudi coffee formulations from the middle and eastern regions. Aidite and Cer ceramics showed less TP values than Emax. Consumption of coffee for a period of simulated 1 year has significantly altered the color of ceramic materials to a level above the threshold at which the clinical perception of color change occurred (> 3.3). Saudi coffee consumption caused less changes in the color of tested ceramics in comparison to the consumption of commonly used coffees (instant black, turkish, and espresso).

本研究的目的是评估沙特咖啡消费量与各种常用咖啡(速溶黑咖啡、土耳其咖啡和浓缩咖啡)对新型美学牙科陶瓷颜色的影响。利用CAD/CAM技术,共制作了144个直径为8mm、厚度为0.5 mm的扁平圆柱形圆盘。使用了三种陶瓷材料:二硅酸锂(Emax)和两种超半透明单片氧化锆陶瓷;Aidite和Cercon Xt (Cer)。将样品浸泡在6种咖啡溶液中:东部地区的沙特咖啡(ES)、北部地区的沙特咖啡(SN)、中部地区的沙特咖啡(SM)、速溶黑咖啡(Ne)、土耳其咖啡(Tk)和浓缩咖啡(ES)。所有标本(n = 8)浸泡15天。在浸泡前后测量所有标本的颜色,并用分光光度计获得CIE L*a* b*坐标。计算每个标本的半透明参数(TP)、对比度(CR)和颜色变化(ΔE)的值。数据分析采用配对样本t检验、单因素方差分析和事后检验。在所有咖啡溶液中浸泡后,颜色坐标L*, a*和b*相对于浸泡前的值发生了显著变化,亮度(L*)明显降低(P 3.3)。与常用的咖啡(速溶黑咖啡、土耳其咖啡和浓缩咖啡)相比,沙特咖啡对测试陶瓷颜色的影响较小。
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引用次数: 0
Results from a five-year clinical assessment of undergraduate-performed direct composite restorations. 对大学生进行直接复合修复的5年临床评估结果。
IF 2.3 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-08 DOI: 10.1007/s44445-025-00041-y
Kiran Rehman, Ng Ke Ying, Adele Woo Huey San, Omer Sheriff Sultan

Resin based dental composites offer significant benefits with regard to the minimally invasive management of dental caries. However, over a period of time such restorations may become susceptible to failure with secondary caries and marginal deterioration being common causes. A retrospective clinical study was conducted at the IMU University Oral Health Centre to assess the quality of direct resin composite restorations placed by dental undergraduates as judged by the modified United States Public Health Service (USPHS), criteria. This study aimed to evaluate the quality and the causes of the failure of direct resin composite restorations in permanent teeth placed by dental undergraduate students using modified USPHS criteria to assess failure. A total of 76 restorations were evaluated in this study. Descriptive statistics were collected, and the Chi-square test (p < 0.05) was used to determine statistically significant differences. A total of 42.1% of the composite resin restorations in the study were considered satisfactory. Of the restorations regarded as failures, the causes were colour mismatch (39.4%), followed by marginal discolouration (21%) and then restoration fracture (14.5%). The operator's year of study (p = 0.039) and the number of restoration surfaces (p = 0.039) showed statistically significant associations with the quality of the restorations. Composite resin restorations performed by dental undergraduates exhibited high failure rates, which were primarily attributed to colour mismatches, marginal dis-colourations, or fractures of the restoration.

树脂基牙科复合材料在龋齿的微创治疗方面提供了显著的好处。然而,经过一段时间,这种修复可能变得容易失败,继发性龋齿和边缘退化是常见的原因。IMU大学口腔健康中心进行了一项回顾性临床研究,根据修订的美国公共卫生服务(USPHS)标准评估牙科本科生放置的直接树脂复合修复体的质量。本研究旨在利用改良的USPHS标准评估牙科本科生固定恒牙直接树脂复合材料修复体失败的质量和原因。本研究共评估了76个修复体。进行描述性统计,卡方检验(p
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引用次数: 0
Temporomandibular joint disorder related to cancer metastasis: A review on reported cases in the literature. 颞下颌关节紊乱与肿瘤转移:文献报道病例回顾。
IF 2.3 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-06 DOI: 10.1007/s44445-025-00043-w
Hamed Mortazavi, Anita Taheri, Sara Alehossein, Mehdi Hashemi

Introduction: Metastasis to the temporomandibular joint is an uncommon clinical entity that often mimics benign temporomandibular disorders, leading to diagnostic challenges. This systematic review aimed to consolidate the existing literature on temporomandibular joint metastasis to delineate its clinical and demographic characteristics, diagnostic pitfalls, and treatment approaches.

Methods: A comprehensive search was conducted across PubMed/MEDLINE, Scopus, and Embase electronic databases. Two independent reviewers screened the titles, abstracts, and full texts of 3,659 articles, ultimately selecting 47 articles encompassing 55 reported cases.

Results: The analysis revealed a mean patient age of 61.8 ± 13.99 years, with a slight female predominance. Lung and breast cancers were the most common primary sites, with adenocarcinoma being the predominant histopathological type. Clinically, pain, swelling, and restricted mouth opening were the most frequently observed symptoms, although a subset of patients presented with atypical features. Notably, in 49% of cases, TMJ metastasis was detected prior to the diagnosis of the primary malignancy. Multimodal treatment, incorporating combinations of chemotherapy, radiotherapy, and surgery, was the most common therapeutic approach.

颞下颌关节转移是一种罕见的临床疾病,通常与良性颞下颌关节疾病相似,导致诊断困难。本系统综述旨在整合关于颞下颌关节转移的现有文献,以描述其临床和人口学特征,诊断陷阱和治疗方法。方法:在PubMed/MEDLINE、Scopus和Embase电子数据库中进行综合检索。两名独立审稿人筛选了3,659篇文章的标题、摘要和全文,最终选择了47篇文章,其中包括55例报告病例。结果:患者平均年龄61.8±13.99岁,女性稍占优势。肺癌和乳腺癌是最常见的原发部位,腺癌是主要的组织病理类型。临床上,疼痛、肿胀和张嘴受限是最常见的症状,尽管一小部分患者表现出非典型特征。值得注意的是,在49%的病例中,TMJ转移在原发恶性肿瘤诊断之前就被发现了。结合化疗、放疗和手术的多模式治疗是最常见的治疗方法。
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引用次数: 0
Influence of deep marginal elevation on the marginal adaptation and fracture resistance of zirconia endocrowns constructed on endodontically treated premolar teeth: in vitro study. 深度边缘抬高对根管治疗前磨牙氧化锆牙冠边缘适应及抗断裂能力的影响
IF 2.3 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-05 DOI: 10.1007/s44445-025-00044-9
Sara Tamimi, Huda I Mostafa, Menna S Ali, Hayam M Tawfik

Introduction: One of the most conservative approaches to restoring teeth that have undergone endodontic treatment is the use of endocrowns. This study evaluated the marginal adaptation and fracture resistance of endodontically treated premolars restored with endocrowns fabricated from translucent multi-layered zirconia ceramic following deep marginal elevation.

Methods: Eighteen freshly extracted intact human maxillary premolars were endodontically treated, and standard endocrown preparations were performed. Specimens were divided into two groups (n = 9 each) based on the location of the proximal margin. Group I: Butt-joint endocrown design with a cavity 2 mm in width and 1 mm above the cemento-enamel junction (CEJ) prepared at the middle of the mesial surface (without deep marginal elevation). Group II: Butt-joint endocrown design with a cavity 2 mm in width and 2 mm below the CEJ prepared at the middle of the mesial surface. Deep marginal elevation (DME) was performed using composite resin. All endocrowns were fabricated from translucent multi-layered zirconia ceramic. Endocrowns were luted using dual-cure adhesive cement. Thermocycling was performed after incubating the samples in distilled water at 37°C for 24 h. Marginal adaptation was examined using a stereomicroscope (× 40) at three specific locations along the mesial border. Fracture resistance was assessed using a universal testing machine.

Results: No statistically significant difference was detected in marginal adaptation or fracture resistance between the two groups (p = 0.121 and 0.589, respectively). Catastrophic failure (fracture below the CEJ) was more frequently observed in both groups.

Conclusion: DME has no significant effect on either marginal adaptation or fracture resistance of premolars restored with multi-layered translucent zirconia endocrowns. DME slightly improved the failure mode.

介绍:修复牙髓治疗后最保守的方法之一是使用牙髓冠。本研究评估了半透明多层氧化锆陶瓷内冠在深度边缘抬高后修复的牙髓治疗前磨牙的边缘适应性和抗骨折性。方法:对18颗新鲜取出的完整人上颌前磨牙进行根管治疗,并进行标准的内冠制备。根据近缘位置将标本分为两组(n = 9)。第一组:对接式内冠设计,在牙髓中表面的中间位置(边缘无深抬高),在牙髓-牙釉质交界处(CEJ)上方1mm处准备一个宽度为2mm的空腔。第二组:对接式内冠设计,在CEJ内侧表面的中间位置制备一个宽度为2mm、距离为2mm的空腔。采用复合树脂进行深度边缘抬高(DME)。所有内冠均由半透明的多层氧化锆陶瓷制成。采用双固化胶粘剂粘接。在37°C蒸馏水中孵育24小时后进行热循环。在中缘的三个特定位置使用体视显微镜(× 40)检查边缘适应性。使用万能试验机评估断裂抗力。结果:两组患者的边缘适应能力和抗骨折能力差异无统计学意义(p = 0.121、0.589)。在两组中,灾难性失败(CEJ以下骨折)更为常见。结论:二甲醚对多层半透明氧化锆内冠修复前磨牙的边缘适应和抗骨折能力均无显著影响。DME略微改善了失效模式。
{"title":"Influence of deep marginal elevation on the marginal adaptation and fracture resistance of zirconia endocrowns constructed on endodontically treated premolar teeth: in vitro study.","authors":"Sara Tamimi, Huda I Mostafa, Menna S Ali, Hayam M Tawfik","doi":"10.1007/s44445-025-00044-9","DOIUrl":"10.1007/s44445-025-00044-9","url":null,"abstract":"<p><strong>Introduction: </strong>One of the most conservative approaches to restoring teeth that have undergone endodontic treatment is the use of endocrowns. This study evaluated the marginal adaptation and fracture resistance of endodontically treated premolars restored with endocrowns fabricated from translucent multi-layered zirconia ceramic following deep marginal elevation.</p><p><strong>Methods: </strong>Eighteen freshly extracted intact human maxillary premolars were endodontically treated, and standard endocrown preparations were performed. Specimens were divided into two groups (n = 9 each) based on the location of the proximal margin. Group I: Butt-joint endocrown design with a cavity 2 mm in width and 1 mm above the cemento-enamel junction (CEJ) prepared at the middle of the mesial surface (without deep marginal elevation). Group II: Butt-joint endocrown design with a cavity 2 mm in width and 2 mm below the CEJ prepared at the middle of the mesial surface. Deep marginal elevation (DME) was performed using composite resin. All endocrowns were fabricated from translucent multi-layered zirconia ceramic. Endocrowns were luted using dual-cure adhesive cement. Thermocycling was performed after incubating the samples in distilled water at 37°C for 24 h. Marginal adaptation was examined using a stereomicroscope (× 40) at three specific locations along the mesial border. Fracture resistance was assessed using a universal testing machine.</p><p><strong>Results: </strong>No statistically significant difference was detected in marginal adaptation or fracture resistance between the two groups (p = 0.121 and 0.589, respectively). Catastrophic failure (fracture below the CEJ) was more frequently observed in both groups.</p><p><strong>Conclusion: </strong>DME has no significant effect on either marginal adaptation or fracture resistance of premolars restored with multi-layered translucent zirconia endocrowns. DME slightly improved the failure mode.</p>","PeriodicalId":47246,"journal":{"name":"Saudi Dental Journal","volume":"37 7-9","pages":"35"},"PeriodicalIF":2.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12325160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antimicrobial efficacy of blueM gel and calcium hydroxide against F. nucleatum and E. faecalis biofilm: an ex-vivo study. 蓝色凝胶和氢氧化钙对具核梭菌和粪肠球菌生物膜的抑菌效果:离体研究。
IF 2.3 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-07-28 DOI: 10.1007/s44445-025-00042-x
Yahya Raja Alharbi, Swati Srivastava, Hanin Alsalhi, Khawlah Almohimeed, Mohammad Alduraibi, Ahmed Nabil

Endodontic treatment failure can result from persistent bacteria, inadequate cleaning and sealing of root canals, and missed canals. The resilience of bacteria such as F. nucleatum and E. faecalis within the root canal system is a significant cause of failed endodontic treatment. Calcium hydroxide (CaOH), a widely utilized intracanal medicament, has demonstrated antimicrobial properties. However, its ability to consistently achieve culture-negative root canals after chemo-mechanical procedures remains inconsistent. This study aimed to evaluate and compare the antimicrobial efficacy of CaOH and BlueM gel against F. nucleatum and E. faecalis biofilms using dentin discs. Sterilized dentin discs were prepared from extracted human teeth. F. nucleatum and E. faecalis were grown on these discs and then treated with either CaOH or BlueM gel. Antimicrobial efficacy was assessed by quantifying colony-forming unit counts. BlueM gel demonstrated significantly greater antimicrobial efficacy than CaOH against both F. nucleatum and E. faecalis biofilms. Both agents exhibited substantial antimicrobial activity against the biofilms. BlueM gel showed superior antimicrobial effectiveness against endodontic pathogens such as F. nucleatum and E. faecalis compared to CaOH.

根管治疗失败的原因可能是细菌持续存在,根管清洁和密封不充分,以及漏根管。有核梭菌和粪肠杆菌等细菌在根管系统内的弹性是导致根管治疗失败的一个重要原因。氢氧化钙(CaOH)是一种广泛应用于肛管内的药物,具有抗菌性能。然而,其在化学机械手术后持续实现培养阴性根管的能力仍然不一致。本研究旨在评价和比较CaOH和BlueM凝胶对牙本质圆盘上的具核梭菌和粪肠球菌生物膜的抑菌效果。从拔除的人牙齿中制备灭菌的牙本质盘。在这些圆盘上培养具核梭菌和粪芽孢杆菌,然后用过氧化氢或BlueM凝胶处理。通过量化菌落形成单位计数来评估抗菌效果。BlueM凝胶对具核梭菌和粪肠球菌生物膜的抑菌效果显著高于CaOH。两种制剂对生物膜均表现出明显的抑菌活性。与氢氧化钙相比,BlueM凝胶对牙髓病原菌(如具核梭菌和粪肠杆菌)的抗菌效果更好。
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引用次数: 0
Neurosensory outcomes following permanent lingual nerve injury in surgical removal of mandibular third molars: a systematic review and meta-analysis. 下颌第三磨牙手术切除后永久性舌神经损伤的神经感觉结果:一项系统回顾和荟萃分析。
IF 2.3 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-07-25 DOI: 10.1007/s44445-025-00033-y
Javad Hayati Garjan, Mojtaba Sheykhian, Mehran Rahbar, Ali Sharifi

Aim: The preset systematic review and meta-analysis aimed to evaluate neurosensory outcomes following permanent lingual nerve injury in the surgical removal of mandibular third molars.

Method: The international databases Cochrane, Embase, and MEDLINE (PubMed and Ovid) were searched for pertinent keywords until January 2025. Eight studies were included, and their risk of bias was evaluated using the Newcastle-Ottawa Scale. Using a random effect model and limited maximum-likelihood techniques of 95 percent confidence intervals (CI), prevalence rates were employed as an effect size. Stata (version 17) was used for meta-analysis.

Result: The prevalence rate of somatosensory following lingual nerve injury after surgical removal of mandibular third molars was 5.58% (ES 5.58% 95% CI; 2.55%, 8.61%). The frequency of pain and gustatory was 36.78% and 3.52%, respectively.

Conclusion: According to the present meta-analysis, the incidence rate of neurosensory outcomes is high after the surgical removal of mandibular third molars and following permanent lingual nerve injury.

目的:系统回顾和荟萃分析旨在评估下颌第三磨牙手术中永久性舌神经损伤后的神经感觉结果。方法:检索国际数据库Cochrane、Embase和MEDLINE (PubMed和Ovid),检索相关关键词至2025年1月。纳入了8项研究,并使用纽卡斯尔-渥太华量表评估其偏倚风险。采用随机效应模型和95%置信区间(CI)的有限最大似然技术,采用患病率作为效应大小。采用Stata (version 17)进行meta分析。结果:下颌第三磨牙拔除术后舌神经损伤的躯体感觉患病率为5.58% (ES 5.58%, 95% CI;2.55%、8.61%)。疼痛和味觉的频率分别为36.78%和3.52%。结论:根据本荟萃分析,下颌第三磨牙手术切除和永久性舌神经损伤后神经感觉预后的发生率较高。
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引用次数: 0
The role of probiotics in the non-surgical management of peri-implantitis: a systematic review. 益生菌在种植体周围炎非手术治疗中的作用:系统综述。
IF 2.3 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-07-22 DOI: 10.1007/s44445-025-00032-z
Abeer S Al-Zawawi

Introduction: Peri-implantitis is an inflammatory condition affecting the supporting structures of dental implants, which can result in bone loss and possible implant failure. Given their potential antimicrobial and immunomodulatory properties, probiotics have been suggested as an adjuvant to Mechanical debridement in the treatment for peri-implantitis. This systematic review aims to assess the effectiveness of probiotics as an adjuvant in non-surgical management of peri-implantitis.

Methods: A thorough literature search was carried out using databases such as PubMed, Scopus, Web of Science, Embase, and Cochrane Library. The search covered studies published between 2015 and 2024, utilizing search string including "probiotics," "peri-implantitis," "dental implants," "adjunctive therapy," "Non-surgical periodontal therapy" and "oral microbiota"."

Results: This review consolidates existing evidence regarding the use of probiotics as a beneficial adjunctive therapy in the treatment of peri-implantitis, offering insights into their clinical significance, mechanisms of action, and potential drawbacks of the treatment protocol.

Conclusion: Probiotics may serve as a beneficial complement to traditional peri-implantitis treatments; however, additional high-quality research is necessary to confirm their effectiveness and long-term advantages.

种植体周围炎是一种影响牙种植体支撑结构的炎症,可导致骨质流失和可能的种植体失败。鉴于其潜在的抗菌和免疫调节特性,益生菌已被建议作为机械清创治疗种植体周围炎的辅助剂。本系统综述旨在评估益生菌作为非手术治疗种植体周围炎的辅助治疗的有效性。方法:利用PubMed、Scopus、Web of Science、Embase、Cochrane Library等数据库进行文献检索。该搜索涵盖了2015年至2024年间发表的研究,使用的搜索字符串包括“益生菌”、“种植体周围炎”、“牙科种植体”、“辅助治疗”、“非手术牙周治疗”和“口腔微生物群”。结果:本综述整合了有关益生菌作为治疗种植体周围炎的有益辅助疗法的现有证据,并对其临床意义、作用机制和治疗方案的潜在缺陷提供了见解。结论:益生菌可作为传统种植体周围炎治疗的有益补充;然而,需要更多的高质量研究来证实它们的有效性和长期优势。
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引用次数: 0
Global prevalence of dental caries in the older people, 1991 to 2024: a systematic review and meta-analysis. 1991年至2024年全球老年人龋齿患病率:系统回顾和荟萃分析
IF 2.3 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-07-19 DOI: 10.1007/s44445-025-00039-6
Yasaman Almasvandi, Narges Ziaei, Mohsen Kazeminia, Parvin Abbasi

Background: Oral health is an integral part of the overall health of the elderly, significantly impacting their physical, social, and psychological well-being. This study aimed to synthesize, summarize, and standardize the results of primary studies, resolve inconsistencies, examine the influence of potential factors, and estimate the global prevalence of dental caries in the elderly through a systematic review and meta-analysis.

Methods: The systematic review and meta-analysis covered studies published from 1991 to November 2024. Relevant articles were identified through searches in international databases, including Embase, PubMed, Scopus, and Web of Science (WoS), using appropriate keywords. The quality of the studies was assessed using the Joanna Briggs Institute (JBI) checklist. Heterogeneity among studies was evaluated using the I2 statistic. Data were analyzed using Comprehensive Meta-Analysis software, version 2.

Results: The initial search yielded 20,374 studies, of which 31 articles with a total sample size of 26,703 individuals met the inclusion criteria for the meta-analysis. The global prevalence of dental caries in the elderly was estimated at 60.7% (95% confidence interval: 54.6%-66.4%). The highest prevalence was observed in the Americas at 79.6% (95% CI: 34.8%-96.6%). Meta-regression analysis revealed that the prevalence of dental caries decreased with larger sample sizes, higher study quality, and older age, while it increased over time (P < 0.05).

Conclusion: The findings indicate a high prevalence of dental caries among the elderly, particularly in the Americas, with an upward trend in recent years. It is recommended that health policymakers prioritize prevention and control measures for this condition.

背景:口腔健康是老年人整体健康不可分割的一部分,对老年人的身体、社会和心理健康有着重要的影响。本研究旨在通过系统综述和荟萃分析,综合、总结和规范主要研究结果,解决不一致之处,检查潜在因素的影响,并估计全球老年人龋齿患病率。方法:系统评价和荟萃分析涵盖1991年至2024年11月发表的研究。通过检索Embase、PubMed、Scopus和Web of Science (WoS)等国际数据库,使用合适的关键词识别相关文章。使用乔安娜布里格斯研究所(JBI)检查表评估研究的质量。采用I2统计量评价研究间的异质性。数据分析采用综合元分析软件,版本2。结果:最初的检索产生了20,374项研究,其中31篇总样本量为26,703人的文章符合meta分析的纳入标准。全球老年人龋齿患病率估计为60.7%(95%可信区间:54.6%-66.4%)。美洲的患病率最高,为79.6% (95% CI: 34.8%-96.6%)。荟萃回归分析显示,随着样本量的增加、研究质量的提高和年龄的增加,龋齿患病率降低,而随着时间的推移,龋齿患病率上升(P结论:研究结果表明,龋齿在老年人中患病率较高,特别是在美洲,近年来呈上升趋势。建议卫生政策制定者优先考虑这种情况的预防和控制措施。
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引用次数: 0
Biomineralization of dental tissues with natural drugs: a comprehensive review. 天然药物在牙组织生物矿化中的应用综述。
IF 2.3 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-07-15 DOI: 10.1007/s44445-025-00036-9
Yuguang Liu, Ziqi Wu

This narrative review systematically examines the emerging role of natural bioactive substances in dental tissue biomineralization. Through comprehensive analysis of peer-reviewed literature (2000-2024) identified via PubMed, Web of Science, and Scopus using keywords including 'natural drugs,' 'biomineralization,' and 'dental restoration,' we evaluate three key aspects: (1) the limitations of current restorative materials (composite resins, adhesives); (2) the mechanisms of natural compounds (collagen protection, mineral deposition, demineralization inhibition); and (3) clinical translation challenges. Our analysis reveals that plant-derived flavonoids, polyphenols, and bioactive peptides show particular promise for enhancing remineralization while addressing toxicity concerns. The review concludes by proposing a research framework for developing next-generation bioactive restorative materials, highlighting knowledge gaps in long-term stability and standardized protocols.

本综述系统地探讨了天然生物活性物质在牙组织生物矿化中的作用。通过对PubMed、Web of Science和Scopus检索到的同行评议文献(2000-2024)进行综合分析,使用关键词包括“天然药物”、“生物矿化”和“牙齿修复”,我们评估了三个关键方面:(1)当前修复材料(复合树脂、粘合剂)的局限性;(2)天然化合物(胶原蛋白保护、矿物质沉积、脱矿抑制)的作用机制;(3)临床翻译的挑战。我们的分析表明,植物衍生的类黄酮、多酚和生物活性肽在解决毒性问题的同时,特别有希望增强再矿化。该综述最后提出了开发下一代生物活性修复材料的研究框架,强调了长期稳定性和标准化方案方面的知识差距。
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Saudi Dental Journal
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