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Bioengineering from the laboratory to clinical translation in oral and maxillofacial reconstruction 口腔颌面重建中从实验室到临床转化的生物工程
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-08 DOI: 10.1016/j.sdentj.2024.05.004
Ola M. Maria , Ashraf Heram , Simon D. Tran

Background

Conventional techniques used in oral and maxillofacial reconstruction focus mainly on utilizing autologous tissues that have unquestionably improved function and esthetics for many patients, worldwide. However, the success depends on countless factors such as: donor and recipient sites conditions, patient’s medical history, surgeon’s experience, restricted availability of high-quality autogenous tissues or stem cells, and increased surgical cost and time.

Materials and Methods

Lately, teaming researchers, scientists, surgeons, and engineers, to address these limitations, have allowed tremendous progress in recombinant protein therapy, cell-based therapy, and gene therapy.

Results

Over the past few years, biomedical engineering has been evolving from the laboratory to clinical applications, for replacement of damaged body tissues due to trauma, cancer, congenital or acquired disorders.

Conclusions

This review provides an outlook on the content, benefits, recent advances, limitations, and future expectations of biomedical engineering for salivary glands, oral mucosa, dental structures, and maxillofacial reconstruction.

背景口腔颌面部重建中使用的传统技术主要侧重于利用自体组织,毫无疑问,自体组织改善了全球许多患者的功能和美观。然而,其成功与否取决于无数因素,例如:供体和受体部位的条件、患者的病史、外科医生的经验、高质量自体组织或干细胞的限制性供应以及手术成本和时间的增加。结果在过去几年中,生物医学工程已从实验室发展到临床应用,用于替代因创伤、癌症、先天性或后天性疾病而受损的身体组织。结论本综述对生物医学工程在唾液腺、口腔粘膜、牙科结构和颌面部重建方面的内容、益处、最新进展、局限性和未来预期进行了展望。
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引用次数: 0
Histogical changes in oral mucosa (gingiva) as a method for estimating post-mortem interval: A literature review 以口腔黏膜(牙龈)的组织学变化作为估算死后间隔时间的方法:文献综述
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-07 DOI: 10.1016/j.sdentj.2024.05.002
Roben Suhadi Pasaribu, Elza Ibrahim Auerkari, Antonius Winoto Suhartono

Estimating the post-mortem interval (PMI) is an essential step in forensic investigations, particularly those involving homicides and unwitnessed deaths. However, traditional methods occasionally yield inconsistent estimates. Histological and molecular techniques are considered crucial in forensic pathology and are frequently employed to estimate the time interval of death. The gingiva is an oral mucosal tissue used to estimate PMI. This review aimed to examine the potential of histological methods to determine PMI using oral mucosal tissue, namely the gingiva, and to investigate changes that occur in oral mucosal tissue at different time intervals when compared with those in normal tissues. The oral mucosa comprises layers of stratified squamous epithelium and connective tissue. Similar to other body tissues, changes are known to occur in the gingiva after death, and these cellular and tissue changes should also be considered. Alterations in the gingiva include homogenisation, karyorrhexis, pyknosis, karyolysis, chromatin clumping, eosinophilia, collagen fibre degradation, and the loss of tissue architecture. Reviews collating the results of original trials have consistently reported how the oral mucosa is altered by autolysis and how such changes can be observed in histological tissue morphology after death. Histology is an acceptably accurate technique for estimating PMIs.

估算死后间隔时间(PMI)是法医调查的重要步骤,尤其是涉及凶杀案和无证人死亡的调查。然而,传统方法偶尔会产生不一致的估计结果。组织学和分子技术被认为是法医病理学的关键,经常被用来估计死亡时间间隔。牙龈是用于估计 PMI 的口腔黏膜组织。本综述旨在研究利用口腔黏膜组织(即牙龈)确定 PMI 的组织学方法的潜力,并研究口腔黏膜组织与正常组织相比在不同时间间隔内发生的变化。口腔黏膜由分层鳞状上皮和结缔组织组成。与身体其他组织类似,已知牙龈在死亡后也会发生变化,这些细胞和组织变化也应考虑在内。牙龈的变化包括:均质化、核分裂、热解、核溶解、染色质结块、嗜酸性粒细胞增多、胶原纤维降解和组织结构丧失。整理原始试验结果的综述一致报告了自溶如何改变口腔黏膜,以及如何在死后的组织形态学中观察到这些变化。组织学是一种可接受的准确估算 PMI 的技术。
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引用次数: 0
Assessment of color stability and translucency of various CAD/CAM ceramics of different compositions and Thicknesses: An in vitro study 评估不同成分和厚度的 CAD/CAM 陶瓷的颜色稳定性和半透明度:体外研究
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-03 DOI: 10.1016/j.sdentj.2024.05.001
Passent Ellakany , Nourhan M. Aly , Shahad T. Alameer , Turki Alshehri , Shaimaa M. Fouda

Background

Translucency and optical characteristics significantly affect the aesthetics of ceramic restorations. The introduction of new virgilite crystals to novel ceramic advanced lithium disilicate through a matrix firing process enhances the material’s strength and aesthetic quality according to the manufacturer.

Materials and Methods

Four types of CAD/CAM ceramics; lithium disilicate (LD), leucite reinforced (LR), advanced lithium disilicate (ALD), and zirconia-reinforced lithium silicate (ZLS) exposed to different staining solutions (tea, cola, coffee, and distilled water). Each ceramic type had 120 specimens, divided into subgroups based on thickness (0.5 mm, 1 mm, and 1.5 mm). Color changes (ΔE00) and translucency parameters (TP00) were measured after thermocycling, and spectrophotometry was employed to evaluate ΔE00 and TP00 after 1, 7, and 30 days of exposure to the staining solutions.

Results

ZLS exhibited the lowest color stability, while lithium LD and ALD displayed the highest. Thickness significantly affected color stability, with 0.5 mm thickness showing the least change. The duration of exposure also impacted color changes, with 30 days causing the most significant shift. LD demonstrated the highest translucency. Coffee and tea induced more pronounced reductions in translucency and color stability compared to the control group.

Conclusions

Material structure, thickness, staining solution, and exposure duration significantly influenced the color stability and translucency of CAD/CAM ceramics, with LD and ALD demonstrating superior color stability and LD exhibiting the highest translucency.

背景半透明性和光学特性对陶瓷修复体的美观有很大影响。材料和方法四种 CAD/CAM 陶瓷:二硅酸锂 (LD)、白云石强化 (LR)、高级二硅酸锂 (ALD) 和氧化锆强化硅酸锂 (ZLS),暴露在不同的染色溶液(茶、可乐、咖啡和蒸馏水)中。每种陶瓷类型有 120 个试样,根据厚度(0.5 毫米、1 毫米和 1.5 毫米)分为若干小组。在热循环后测量颜色变化(ΔE00)和半透明参数(TP00),并采用分光光度法评估暴露在染色溶液中 1、7 和 30 天后的ΔE00 和 TP00。厚度对颜色稳定性的影响很大,0.5 毫米的厚度变化最小。暴露时间的长短也会影响颜色的变化,30 天的变化最为明显。LD 的半透明度最高。结论材料结构、厚度、染色溶液和暴露时间对 CAD/CAM 陶瓷的颜色稳定性和半透明度有显著影响,其中 LD 和 ALD 表现出更高的颜色稳定性,LD 表现出最高的半透明度。
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引用次数: 0
Crystal methamphetamine and its effects on mental and oral health: A narrative review 冰毒及其对精神和口腔健康的影响:叙述性综述
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-01 DOI: 10.1016/j.sdentj.2024.02.011
Hatem Alqarni , Adhwaa Aldghim , Rose Alkahtani , Nasser Alshahrani , Majed S. Altoman , Mohammed A. Alfaifi , Mohammad Helmi , Abdulaziz A. Alzaid

The purpose of this comprehensive literature review is to present the available evidence on the effects of methamphetamine on mental and oral health, as well as provide an overview of the most widely used medical and dental care strategies in the management of meth mouth. For this purpose, PubMed and Google Scholar electronic databases were searched for relevant articles, yielding 115 search results, which were further scrutinized for their relevance, leaving 55 for a detailed review. The analysis of the gathered data indicates that a comprehensive patient-centered approach that takes into consideration the physical, mental, and social aspects is crucial for mitigating the detrimental effects of increasing methamphetamine use.

本综合文献综述旨在介绍甲基苯丙胺对精神和口腔健康影响的现有证据,并概述在治疗冰毒口腔方面最广泛使用的医疗和牙科护理策略。为此,研究人员在 PubMed 和 Google Scholar 电子数据库中搜索了相关文章,共获得 115 条搜索结果,并对这些结果的相关性进行了进一步审查,最后剩下 55 条进行了详细审查。对收集到的数据进行的分析表明,以患者为中心、考虑到生理、心理和社会方面的综合方法对于减轻甲基苯丙胺使用增加所带来的有害影响至关重要。
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引用次数: 0
Is fatigue mechanism implicated in intraoral fracture of narrow dental implants? A thorough retrieval analysis of two failed implant fixtures retrieved from a single patient 窄口种植体口内骨折是否与疲劳机制有关?对从一名患者身上取回的两个失败种植体固定装置的彻底取回分析
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-01 DOI: 10.1016/j.sdentj.2024.02.006
Youssef S. Al Jabbari , Raymond Fournelle , Arif Sufyan , Spiros Zinelis

Purpose

This study aimed to perform a thorough failure analysis of two fractured narrow dental implants after medium-term in vivo use.

Materials and methods

The top parts of two fractured Narrow Dental Implant (NDI) fixtures were retrieved from two different locations at two different times from the same patient. The NDI-specimen-1 was 12-months in service while the NDI-specimen-2 was 17-months in service. In both cases, the top parts of the fractured NDI fixtures that were attached to prosthetic components were retrieved and subjected to thorough, non-destructive and destructive testing.

Results

Light Microscopy (LM) and Scanning Electron Microscopy (SEM) revealed that both the retrieved fractured NDIs failed because of fatigue, characterized by beach and ratchet marks. Macroscopic examination revealed that fatigue cracks initiated at the internal thread surfaces of the implants and propagated around them until final fracture. Both samples fractured near the end of the retaining screw and followed the root of the internal thread. Optical and SEM analyses revealed a uniform distribution of irregularly shaped grains (diameter = 2 to 5 μm). X -ray Energy Dispersive Spectroscopy (EDS) analysis showed that the NDI-specimen-1 was made using Ti-14%Zr with a Vickers Hardens (HV) of 288 ± 5.

Conclusion

Since the fracture occurred by a fatigue; thus, an increase in fatigue resistance will be beneficial for the longevity of NDI.

材料和方法在同一患者的两个不同时间,从两个不同位置取回了两个断裂的窄牙种植体(Narrow Dental Implant,NDI)的顶部。NDI 样本-1 使用了 12 个月,而 NDI 样本-2 使用了 17 个月。结果光学显微镜(LM)和扫描电子显微镜(SEM)显示,取回的两个断裂的 NDI 都因疲劳而失效,其特征是有沙滩和棘轮痕迹。宏观检查显示,疲劳裂纹始于植入物的内螺纹表面,并在其周围扩展,直至最终断裂。两个样品都是在固定螺钉末端附近断裂,并沿着内螺纹根部断裂。光学和扫描电镜分析表明,不规则形状的晶粒(直径 = 2 至 5 μm)分布均匀。X 射线能量色散光谱(EDS)分析表明,NDI-试样-1 是用 Ti-14%Zr 制成的,维氏硬度(HV)为 288 ± 5。
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引用次数: 0
Influence of post-processing on the adhesion of dual-species biofilm on polylactic acid obtained by additive manufacturing 后处理对通过增材制造获得的聚乳酸上双种生物膜附着力的影响
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-01 DOI: 10.1016/j.sdentj.2024.03.001
Izabela Ferreira , Murilo Rodrigues de Campos , Beatriz Danieletto Sahm , Mariana Lima da Costa Valente , José Augusto Marcondes Agnelli , Andréa Cândido dos Reis

Introduction

Post-processing (PP) is performed to improve the surface, which can favor microbial adhesion and consequent pathological manifestations that impair the indication of polylactic acid (PLA) obtained by fused filament fabrication (FFF) for biomedical applications. This aims to evaluate the influence of chemical, thermal, and mechanical PP on the adhesion of Streptococcus mutants and Candida albicans, roughness, and wettability of the PLA obtained by FFF with and without thermal aging.

Methods

The specimens were designed in the 3D modeling program and printed. The chemical PP was performed by immersion in chloroform, the thermal by the annealing method, and the mechanical by polishing. Thermal aging was performed by alternating the temperature from 5 °C to 55 °C with 5000 cycles. Colony-forming unit (CFU/mL) counting was performed on dual-species biofilm of C. albicans and S. mutans. Roughness was analyzed by rugosimeter and wettability by the sessile drop technique. Data were verified for normality using the Shapiro-Wilk test, two-way ANOVA (α = 0.05) applied for CFU and wettability, and Kruskal-Wallis (α = 0.05) for roughness.

Results

Chemical, thermal, and mechanical PP methods showed no influence on CFU/mL of C. albicans (p = 0.296) and S. mutans (p = 0.055). Thermal aging did not influence microbial adhesion. Chemical PP had lower roughness, which had increased after aging. Wettability of the mechanical PP was lower.

Conclusions

Post-processing techniques, do not present an influence on the adhesion of S. mutans and C. albicans in PLA obtained by FFF, chemical PP reduced roughness, and mechanical reduced wettability. Thermal aging did not alter the microbial adhesion and altered the roughness and wettability.

引言 后处理(PP)是为了改善聚乳酸(PLA)的表面而进行的,它可能有利于微生物的附着,从而导致病理表现,损害通过熔融长丝制造(FFF)获得的聚乳酸(PLA)在生物医学应用中的适应性。本文旨在评估化学、热和机械 PP 对热老化和未热老化情况下通过 FFF 制得的聚乳酸的链球菌突变体和白色念珠菌的粘附性、粗糙度和润湿性的影响。试样在三维建模程序中设计并打印,在氯仿中浸泡进行化学聚丙烯处理,退火法进行热处理,抛光法进行机械处理。热老化是通过从 5 °C 到 55 °C 的温度交替循环 5000 次进行的。菌落形成单位(CFU/mL)计数是在白种人和变异人的双种生物膜上进行的。粗糙度用粗糙度仪分析,润湿性用无梗水滴技术分析。数据采用 Shapiro-Wilk 检验进行正态性验证,CFU 和润湿性采用双向方差分析(α = 0.05),粗糙度采用 Kruskal-Wallis 检验(α = 0.05)。热老化不会影响微生物的附着力。化学聚丙烯的粗糙度较低,老化后粗糙度增加。结论 后处理技术对通过 FFF 获得的聚乳酸中的变异杆菌和白喉杆菌的粘附没有影响,化学聚丙烯降低了粗糙度,而机械聚丙烯降低了润湿性。热老化不会改变微生物的粘附性,但会改变粗糙度和润湿性。
{"title":"Influence of post-processing on the adhesion of dual-species biofilm on polylactic acid obtained by additive manufacturing","authors":"Izabela Ferreira ,&nbsp;Murilo Rodrigues de Campos ,&nbsp;Beatriz Danieletto Sahm ,&nbsp;Mariana Lima da Costa Valente ,&nbsp;José Augusto Marcondes Agnelli ,&nbsp;Andréa Cândido dos Reis","doi":"10.1016/j.sdentj.2024.03.001","DOIUrl":"10.1016/j.sdentj.2024.03.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Post-processing (PP) is performed to improve the surface, which can favor microbial adhesion and consequent pathological manifestations that impair the indication of polylactic acid (PLA) obtained by fused filament fabrication (FFF) for biomedical applications. This aims to evaluate the influence of chemical, thermal, and mechanical PP on the adhesion of <em>Streptococcus mutants</em> and <em>Candida albicans</em>, roughness, and wettability of the PLA obtained by FFF with and without thermal aging.</p></div><div><h3>Methods</h3><p>The specimens were designed in the 3D modeling program and printed. The chemical PP was performed by immersion in chloroform, the thermal by the annealing method, and the mechanical by polishing. Thermal aging was performed by alternating the temperature from 5 °C to 55 °C with 5000 cycles. Colony-forming unit (CFU/mL) counting was performed on dual-species biofilm of <em>C. albicans</em> and <em>S. mutans</em>. Roughness was analyzed by rugosimeter and wettability by the sessile drop technique. Data were verified for normality using the Shapiro-Wilk test, two-way ANOVA (α = 0.05) applied for CFU and wettability, and Kruskal-Wallis (α = 0.05) for roughness.</p></div><div><h3>Results</h3><p>Chemical, thermal, and mechanical PP methods showed no influence on CFU/mL of <em>C. albicans</em> (p = 0.296) and <em>S. mutans</em> (p = 0.055). Thermal aging did not influence microbial adhesion. Chemical PP had lower roughness, which had increased after aging. Wettability of the mechanical PP was lower.</p></div><div><h3>Conclusions</h3><p>Post-processing techniques, do not present an influence on the adhesion of <em>S. mutans</em> and <em>C. albicans</em> in PLA obtained by FFF, chemical PP reduced roughness, and mechanical reduced wettability. Thermal aging did not alter the microbial adhesion and altered the roughness and wettability.</p></div>","PeriodicalId":47246,"journal":{"name":"Saudi Dental Journal","volume":"36 5","pages":"Pages 733-739"},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1013905224000750/pdfft?md5=489e0b5cc0d2952f11c9fc87d6b483ab&pid=1-s2.0-S1013905224000750-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140091326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dental esthetic screening index (DESI) scores among patients attending Qassim University dental clinics 卡西姆大学牙科诊所就诊患者的牙齿美学筛查指数(DESI)得分
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-01 DOI: 10.1016/j.sdentj.2024.04.007
Norah M Almufadhi , Ola.M. Sakr , Lina Aloufi

Aim

This study aimed to evaluate dental esthetic screening index (DESI) Intraoral component scores among patients attending Qassim University dental clinics and the factors affecting these scores.

Materials and methods

This was a retrospective study that included 150 participants aged 18 years or older with full upper and lower anterior dentitions. Standardized intraoral frontal photographs of the patients’ upper and lower dentitions were acquired from their dental records, and the mean rank DESI intraoral scores were evaluated and compared across the demographic and dental characteristics of the study patients.

The mean age of the patients sampled was 33.56; 57 % were female and 43 % were male. The mean DESI Intraoral score was 15.33. DESI scores were significantly higher in patients older than 35 years compared with subjects 35 years old or younger (p = 0.015). DESI scores were increased in patients who had anterior restorations compared with those who did not (p = 0.016).

Conclusions

This was the first study of its kind to use the DESI in a large clinical setting. According to the DESI, most patients attending Qassim University dental clinics had good dentofacial aesthetics. Age and the presence of anterior restorations negatively impacted patients' dentofacial aesthetics. Sex, the nature of the chief complaint, a history of orthodontic treatments, and teeth bleaching did not affect the DESI scores.

本研究旨在评估卡西姆大学牙科诊所就诊患者的牙齿美学筛查指数(DESI)口内评分以及影响这些评分的因素。从患者的牙科病历中获取了患者上下牙的标准化口内正面照片,评估了 DESI 口内评分的平均等级,并对研究患者的人口和牙科特征进行了比较。DESI 口腔内评分的平均值为 15.33 分。与 35 岁或 35 岁以下的受试者相比,35 岁以上患者的 DESI 分数明显更高(p = 0.015)。有前牙修复体的患者与没有前牙修复体的患者相比,DESI 得分更高(p = 0.016)。根据 DESI,在卡西姆大学牙科诊所就诊的大多数患者都有良好的颌面美观。年龄和前牙修复体的存在对患者的颌面美观有负面影响。性别、主诉性质、正畸治疗史和牙齿漂白并不影响 DESI 分数。
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引用次数: 0
A comparison between clinical and digital images with various resolutions to evaluate glass ionomer cement restoration on primary teeth 比较不同分辨率的临床图像和数字图像,以评估基牙的玻璃离聚体水泥修复效果
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-01 DOI: 10.1016/j.sdentj.2024.02.014
Irdra Lastyautari , Mochamad Fahlevi Rizal , Eva Fauziah

Introduction

Dental photography has increasingly been used in practice. One of the purposes of dental photography is for treatment evaluation. Notably, photo resolution affects a picture’s quality. Glass ionomer cement (GIC) restorations are frequently used on pediatric teeth and must be evaluated periodically. In this digital era, digital photos can be used to evaluate restorations. The evaluation of restorations using FDI criteria is typically effective in clinical uses.

Objective

This study aims to compare differences in digital photo resolution and clinical results to evaluate GIC restoration in primary teeth.

Materials and methods

Forty mandibular primary first molars from 31 pediatric patients aged 4 to 9 years from Universitas Indonesia dental hospital were included in this study. All teeth were examined and clinically evaluated, and photos were taken using a DSLR camera with low resolution (8 MP), medium resolution (15 MP), and high resolution (32 MP). The photos were then evaluated. Clinical GIC restorations and digital photographs were evaluated using FDI criteria. All of the collected data were analyzed using a Pearson’s chi-square categorical comparative test with a significance level of p < 0.05.

Result

Based on the comparative test, there were no statistically significant differences in the clinical groups with low resolution, medium resolution, and high resolution for evaluating GIC restorations in primary teeth.

Conclusion

Digital photography can be used to support the evaluation of restoration status. Digital photos can indicate the clinical state of GIC restorations. This study recommends using digital photos between low and medium resolution (8–15.3 MP) as media in dental practices to evaluate GIC restorations in primary teeth, comparable to smartphone cameras or pocket cameras.

引言 牙科摄影越来越多地应用于临床。牙科摄影的目的之一是进行治疗评估。值得注意的是,照片的分辨率会影响照片的质量。玻璃离子粘固剂(GIC)修复体经常用于儿童牙齿,必须定期进行评估。在这个数字化时代,可以使用数码照片对修复体进行评估。本研究旨在比较数码照片分辨率和临床结果的差异,以评估基牙的玻璃离子粘接剂修复。材料和方法本研究纳入了印度尼西亚大学牙科医院 31 名 4 至 9 岁儿童患者的 40 颗下颌基牙。对所有牙齿进行了检查和临床评估,并使用数码单反相机拍摄了低分辨率(800 万像素)、中分辨率(1500 万像素)和高分辨率(3200 万像素)的照片。然后对照片进行评估。使用 FDI 标准对临床 GIC 修复体和数码照片进行评估。所有收集到的数据均采用皮尔逊卡方分类比较试验进行分析,显著性水平为 p <0.05。结果根据比较试验,低分辨率、中分辨率和高分辨率临床组在评估基牙 GIC 修复体方面没有显著的统计学差异。数码照片可以显示 GIC 修复体的临床状态。本研究建议在牙科诊所中使用中低分辨率(8-15.3MP)的数码照片作为评估基牙GIC修复体的媒体,其分辨率可与智能手机摄像头或口袋相机相媲美。
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引用次数: 0
Exploring vital pulp Therapies: A bibliometric analysis of the most cited articles 探索重要的纸浆疗法:对引用次数最多的文章进行文献计量分析
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-01 DOI: 10.1016/j.sdentj.2024.02.007
Gustavo Henrique Sousa , Rodolfo Lima Gonçalves , Barbara Figueiredo , Vilton Cardozo Moreira Dias , Ana Carolina Soares Mendes , Valéria de Cássia Bueno Melo , Adriana Guimarães Rodrigues , Hebertt Gonzaga dos Santos Chaves

Aim

The aim of this study was to identify and analyze the most cited articles on vital pulp therapies.

Methodology

Bibliographical data related to the abstract, citations, keywords, and other relevant information was extracted using different combinations of keywords. Further evaluation and visualization of the selected data were performed with the help of various tools, including MS Excel, Microsoft Word, Google open refine, BibExcel, and VOS viewer. An initial search revealed 91 documents, of which 40 were chosen for further analysis. We used the Kolmogorov–Smirnov test and Spearman correlation coefficient test, and our adopted significance level was p < 0.05.

Results

In total, the articles received 1,905 citations, with six of them receiving at least 100 citations. Among the top 40 articles, the United States of America (10 articles) and Ireland (6 articles) were the countries with the highest number of cited articles. The journals “Journal of Endodontics” (14 articles; 650 citations) and “International Endodontic Journal” (13 articles; 577 citations) published most of the articles among the 50 most cited ones. Duncan H. was the author with the highest number of works cited (11 articles; 339 citations). Of the articles, systematic reviews accounted for 32%, literature reviews for 14%, in vitro experimental studies for 12%, clinical trials for 8%. Among the biomaterials used in vital pulp therapies, mineral trioxide aggregate (MTA) was discussed in 37 articles (74%), followed by calcium hydroxide, mentioned in 30 studies (60%). Interestingly, the publication year did not demonstrate a significant impact on citation count.

Conclusion

The present study provided a detailed list of the top 50 most cited and classic articles on vital pulp therapies. This will help researchers, students, and clinicians in the field of endodontics with an impressive source of information.

本研究的目的是识别和分析被引用次数最多的有关牙髓疗法的文章。方法使用不同的关键词组合提取与摘要、引用、关键词和其他相关信息有关的文献数据。在 MS Excel、Microsoft Word、Google open refine、BibExcel 和 VOS viewer 等多种工具的帮助下,对所选数据进行了进一步评估和可视化。初步搜索发现了 91 份文件,其中 40 份被选中进行进一步分析。我们使用了 Kolmogorov-Smirnov 检验和 Spearman 相关系数检验,采用的显著性水平为 p < 0.05。在被引用次数最多的前 40 篇文章中,美国(10 篇)和爱尔兰(6 篇)是被引用次数最多的国家。在被引用次数最多的 50 篇文章中,《牙髓病学杂志》(14 篇;650 次引用)和《国际牙髓病学杂志》(13 篇;577 次引用)发表的文章最多。Duncan H. 是被引用次数最多的作者(11 篇文章;339 次引用)。在这些文章中,系统综述占 32%,文献综述占 14%,体外实验研究占 12%,临床试验占 8%。在用于牙髓治疗的生物材料中,有37篇文章(74%)讨论了三氧化二矿骨料(MTA),其次是氢氧化钙,有30篇研究(60%)提到了氢氧化钙。有趣的是,发表年份对引用次数并无明显影响。 结论本研究提供了一份关于牙髓疗法的前 50 篇最常被引用的经典文章的详细列表。这将为牙髓病学领域的研究人员、学生和临床医生提供令人印象深刻的信息来源。
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引用次数: 0
Navigating the practical-knowledge gap in deep margin elevation: A step towards a structured case selection – a review 填补深部边缘抬高术的实践知识空白:向结构化病例选择迈出一步--综述
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-01 DOI: 10.1016/j.sdentj.2024.02.022
Eman H. Ismail , Saba S. Ghazal , Rahaf D. Alshehri , Hajar N. Albisher , Rana S. Albishri , Abdulrahman A. Balhaddad

The deep margin elevation (DME) technique has gained popularity because of numerous supporting case reports. However, some clinicians are cautious regarding using this technique owing to the lack of clear case selection criteria for DME application. This review aimed to analyze case reports and a series of DME cases to determine pre-/post-operative evaluation methods that could be used to suggest a pre-operative case selection checklist for DME. An electronic database search was conducted in June 2021 and updated by June 2023 using selected terms from PubMed, Cochrane Library, Google Scholar, EBSCO, and Scopus. The search was limited to English-language publications and was not restricted to the date. The inclusion criteria were case reports/series addressing periodontal and restorative outcomes of DME. The search identified 217 articles, 76 of which were pertinent. However, only six case reports and one case series satisfied the inclusion criteria. None of the selected studies followed any reporting guidelines, which led to significant information gaps. While the reviewed studies reported favorable outcomes, standardized protocols for evaluating pre-/post-operative restorative and periodontal status were lacking. The post-operative follow-up period varied from 3 months to 6 years. Designing and implementing pre-/post-operative guidelines hold the potential for ensuring the safe application of the DME technique. This may enhance our understanding of the suitability and efficacy of such non-invasive technique in future clinical trials.

Clinical significance

Handling deep cavities and preparing crowns are challenging. However, a lack of understanding of when to perform DME can lead to missed opportunities for conservative treatment, thereby a disservice to the patient. Provision of safe guidelines should be employed by clinicians until further evidence either supports or contradicts this treatment method.

深缘抬高(DME)技术因大量支持性病例报告而广受欢迎。然而,由于缺乏明确的 DME 应用病例选择标准,一些临床医生对使用该技术持谨慎态度。本综述旨在分析病例报告和一系列DME病例,以确定可用于建议DME术前病例选择清单的术前/术后评估方法。我们于 2021 年 6 月使用 PubMed、Cochrane Library、Google Scholar、EBSCO 和 Scopus 中的选定术语进行了电子数据库检索,并于 2023 年 6 月进行了更新。搜索仅限于英文出版物,且不限日期。纳入标准为涉及牙周病和 DME 修复结果的病例报告/系列文章。搜索发现了 217 篇文章,其中 76 篇是相关的。然而,只有六篇病例报告和一篇系列病例符合纳入标准。所选研究均未遵循任何报告指南,导致信息严重缺失。虽然所审查的研究报告了良好的结果,但缺乏评估术前/术后修复和牙周状况的标准化方案。术后随访时间从 3 个月到 6 年不等。设计和实施术前/术后指南有可能确保 DME 技术的安全应用。临床意义处理深龋和准备牙冠是一项挑战。然而,如果对何时进行 DME 缺乏了解,就会错失保守治疗的机会,从而对患者造成伤害。在进一步的证据支持或否定这种治疗方法之前,临床医生应采用安全的指导原则。
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Saudi Dental Journal
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