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Impacts of Breaching Planetary Boundaries on Human Health: Current and Future Threats 突破地球边界对人类健康的影响:当前和未来的威胁
IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2025-05-31 DOI: 10.1029/2024GH001107
Ricky Anak Kemarau, Zaini Sakawi, Oliver Valentine Eboy, Wan Shafrina Wan Mohd Jaafar, Zulfaqar Sa'adi, Stanley Anak Suab

This review examines the impact of breaching planetary boundaries on human health and potential future threats, emphasizing the need for effective mitigation and adaptation strategies. Through a rigorous literature review of 142 high-quality articles, we explore the health implications of breaching planetary boundaries such as climate change, land system change, biodiversity loss, biogeochemical flows, aerosol loading, stratospheric ozone depletion, freshwater use, novel entities, and ocean acidification. Our findings indicate a direct association between breached planetary boundaries and a range of health risks, including respiratory and cardiovascular diseases, increased infectious disease vulnerability, and nutritional impacts due to compromised food sources. The analysis highlights the disproportionate effects on vulnerable populations and underscores the significance of localized and global strategies in mitigating these health threats. Effective measures, including urban planning for green spaces and pollution control, have been identified as crucial. The review calls for an integrated, interdisciplinary approach to safeguard human health against the backdrop of environmental degradation, stressing the urgency of global collaboration in policy development and implementation.

本次审查审查了突破地球边界对人类健康的影响和未来的潜在威胁,强调需要制定有效的缓解和适应战略。通过对142篇高质量文章的严格文献综述,我们探讨了突破地球边界对健康的影响,如气候变化、土地系统变化、生物多样性丧失、生物地球化学流动、气溶胶负荷、平流层臭氧消耗、淡水利用、新型实体和海洋酸化。我们的研究结果表明,突破地球边界与一系列健康风险之间存在直接关联,包括呼吸系统和心血管疾病、传染病易感性增加以及食物来源受损造成的营养影响。分析强调了对弱势群体的不成比例的影响,并强调了地方和全球战略在减轻这些健康威胁方面的重要性。包括城市绿地规划和污染控制在内的有效措施被认为是至关重要的。该审查呼吁在环境退化的背景下采取综合的、跨学科的办法来保障人类健康,并强调迫切需要在政策制定和执行方面进行全球合作。
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引用次数: 0
Health-Related Quality of Life and Everyday Functioning in the Flood-Affected Population in Germany - A Case Study of the 2021 Floods in West Germany 德国受洪水影响人口的健康相关生活质量和日常功能——以2021年西德洪水为例
IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2025-05-29 DOI: 10.1029/2024GH001135
Nivedita Sairam, Anna Buch, Marie-Luise Zenker, Lisa Dillenardt, Michaela Coenen, Annegret H. Thieken, Caroline Jung-Sievers

Floods lead to adverse impacts not only in financial terms but also on the health of the exposed population. We report on health-related Quality of Life (QoL) and functioning in the population affected by the 2021 flooding in Germany using an empirical survey data set. Health-related QoL and functioning are represented by two scores–(a) The EuroQoL 5D Visual Analog Scale (EQ-5D VAS) and (b) The 12-Item World Health Organization Disability Assessment Schedule (WHODAS 2.0), respectively. By applying an incremental linear regression model and Machine Learning models, we infer that health-related QoL and functioning are strongly negatively related to the psychological burden from those being affected by the flooding. This includes how often they think about the traumatic event. Home owners were found to have worse QoL and functioning than tenants. Household income and the status of repair/reconstruction of flood damages—in specific, insurance benefits, private donation and satisfactory claims compensation are associated with high health-related QoL and functioning. These findings highlight the importance of strengthening the health-related QoL of flood affected populations and emphasizes the strong association between recovery and health-related QoL and functioning of flood-affected populations.

洪水不仅在财政方面造成不利影响,而且对受影响人口的健康也造成不利影响。我们使用实证调查数据集报告了受2021年德国洪水影响的人群的健康相关生活质量(QoL)和功能。与健康相关的生活质量和功能由两个分数表示- (a) EuroQoL 5D视觉模拟量表(EQ-5D VAS)和(b) 12项世界卫生组织残疾评估表(WHODAS 2.0)。通过应用增量线性回归模型和机器学习模型,我们推断与健康相关的生活质量和功能与受洪水影响的人的心理负担呈强烈负相关。这包括他们想起创伤性事件的频率。房主的生活质量和功能比租户差。家庭收入和洪水灾害的修复/重建状况(具体而言,保险福利、私人捐赠和令人满意的索赔赔偿)与较高的健康相关生活质量和功能相关。这些发现强调了加强洪水受灾人群健康相关生活质量的重要性,并强调了恢复与健康相关生活质量和洪水受灾人群功能之间的密切联系。
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引用次数: 0
Association of Ambient Temperature and Relative Humidity With Respiratory Syncytial Virus Infections Among Hospitalized Children in Suzhou, Eastern China: A Time-Series Analysis 苏州地区住院儿童环境温度和相对湿度与呼吸道合胞体病毒感染的关系:时间序列分析
IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2025-05-21 DOI: 10.1029/2025GH001353
Yingfeng Lu, Shaolong Ren, Xuejun Shao, Jianmei Tian, Feifei Hu, Fang Yao, Tao Zhang, Genming Zhao

Respiratory syncytial virus (RSV) is the leading cause of clinical pneumonia in children. We aimed to investigate the associations between ambient temperature, relative humidity, and pediatric RSV infections, and to assess the disease burden attributable to cold or humid conditions. Daily data on RSV hospitalizations among children aged ≤5 years, mean temperature, and relative humidity in Suzhou, China, from January 2016 to December 2019 were collected. A distributed lag nonlinear model with quasi-Poisson regression was employed to assess the exposure-lag-response associations. Attributable risks were calculated to quantify the disease burden due to climatic factors. We found an inverted U-shaped relationship between temperature and RSV infections, with the cumulative risk of RSV peaking at 7.5°C (RR = 4.30, 95% CI: 3.08–6.02). The exposure-response curves for relative humidity exhibited a generally positive trend, peaking at 100.0% (RR = 3.14, 95% CI: 1.84–5.34). Using median values as references, the highest risk effects of extremely low (RR = 1.14, 95% CI: 1.04–1.25) and low (RR = 1.22, 95% CI: 1.12–1.32) temperatures, as well as high (RR = 1.09, 95% CI: 1.04–1.13) and extremely high (RR = 1.16, 95% CI: 1.07–1.27) relative humidity, occurred on the day of exposure and persisted for extended periods. The attributable fraction of RSV infections associated with cold or humid conditions was 55.23% (95% CI: 50.01%–64.03%) and 12.02% (95% CI: 9.36%–20.24%), respectively. The risk effect of high relative humidity was stronger in children aged 1–5 years. Our findings suggest nonlinear, lagged associations between climatic factors and pediatric RSV infections, which may inform future healthcare planning and RSV immunization strategies.

呼吸道合胞病毒(RSV)是儿童临床肺炎的主要原因。我们的目的是调查环境温度、相对湿度和儿童呼吸道合气道病毒感染之间的关系,并评估由寒冷或潮湿条件引起的疾病负担。收集2016年1月至2019年12月中国苏州≤5岁儿童RSV住院、平均温度和相对湿度的每日数据。采用拟泊松回归的分布滞后非线性模型来评估暴露-滞后-反应关系。计算归因风险以量化气候因素造成的疾病负担。我们发现温度与RSV感染之间呈倒u型关系,RSV的累积风险在7.5°C时达到峰值(RR = 4.30, 95% CI: 3.08-6.02)。相对湿度的暴露响应曲线总体呈正相关,在100.0%处达到峰值(RR = 3.14, 95% CI: 1.84 ~ 5.34)。使用中位数作为参考,极低(RR = 1.14, 95% CI: 1.04-1.25)和低(RR = 1.22, 95% CI: 1.12-1.32)温度以及高(RR = 1.09, 95% CI: 1.04-1.13)和极高(RR = 1.16, 95% CI: 1.07-1.27)相对湿度的最高风险效应发生在暴露当天并持续较长时间。RSV感染与寒冷或潮湿环境相关的归因比例分别为55.23% (95% CI: 50.01%-64.03%)和12.02% (95% CI: 9.36%-20.24%)。高相对湿度对1 ~ 5岁儿童的危险效应更强。我们的研究结果表明,气候因素与儿童RSV感染之间存在非线性滞后关联,这可能为未来的医疗保健计划和RSV免疫策略提供信息。
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引用次数: 0
The Non-Linear Effects of Urban Green Space on Promoting Physical Activity of Old Adults at Different Obesity Status in Semi-Arid Area: A Case Study of Lanzhou, China 半干旱区城市绿地对不同肥胖状态老年人身体活动的非线性促进效应——以兰州市为例
IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2025-05-21 DOI: 10.1029/2024GH001273
Hualong Qiu, Haoran Tang, Yiyang Yang

A substantial body of research has linked the built environment to obesity risk in older adults, with physical activity reducing obesity risk. Most studies have focused on temperate and subtropical regions; however, results can vary due to different climate characteristics. This study examines Lanzhou, a representative of arid Northwestern China, to explore the nonlinear relationship between the built environment and physical activity among older adults, focusing on the role of green spaces. By using the XGBoost method, we analyze how green spaces and the 5D built environment affect physical activity levels among the obese and standard-weight elderly populations in Lanzhou. Results indicate that green spaces significantly influence physical activity in both groups, with their effect surpassing other environmental and sociodemographic factors. Obese elderly individuals are more influenced by green space quality and accessibility, while standard-weight individuals are more affected by the overall quantity and coverage of green spaces. Obese individuals also rely more on street greening compared with their standard-weight counterparts. In addition, a diverse urban environment and appropriate public transportation distances are crucial for promoting physical activity among the elderly. Low temperatures inhibit physical activity more in obese elderly individuals. Our findings provide insights for policymakers, planners, and designers on optimizing green infrastructure to reduce obesity risks among the elderly in arid regions, ultimately enhancing the urban environment's effectiveness in promoting healthy aging.

大量研究已经将建筑环境与老年人肥胖风险联系起来,而体育活动可以降低肥胖风险。大多数研究集中在温带和亚热带地区;然而,由于不同的气候特征,结果可能有所不同。本研究以中国西北干旱地区为代表的兰州为研究对象,探讨了建筑环境与老年人身体活动之间的非线性关系,重点关注绿地的作用。采用XGBoost方法,分析了绿地和5D建成环境对兰州市肥胖和标准体重老年人身体活动水平的影响。结果表明,绿地对两组人群的身体活动都有显著影响,其影响超过了其他环境和社会人口因素。肥胖老年人更受绿地质量和可达性的影响,而标准体重老年人更受绿地总体数量和覆盖率的影响。与体重正常的人相比,肥胖的人也更依赖于街道绿化。此外,多样化的城市环境和适当的公共交通距离对于促进老年人的身体活动至关重要。低温更能抑制肥胖老年人的身体活动。我们的研究结果为决策者、规划者和设计师提供了优化绿色基础设施以降低干旱地区老年人肥胖风险的见解,最终提高城市环境促进健康老龄化的有效性。
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引用次数: 0
PM2.5-Associated Premature Mortality Attributable to Hot-And-Polluted Episodes and the Inequality Between the Global North and the Global South 高温和污染事件导致的pm2.5相关过早死亡以及全球南北之间的不平等
IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2025-05-13 DOI: 10.1029/2024GH001290
Tao Huang, Yue Li, Jinhui Li, Joseph J. Y. Sung, Steve H. L. Yim

Exposure to air pollution and excessive heat during hot-and-polluted episodes (HPEs) may synergistically cause higher health risks globally. Nevertheless, long-term global spatiotemporal characteristics of HPEs and their health impacts remain unclear. Herein, we conducted statistical analyses using reanalysis data of fine particulate matter (PM2.5) and climate together with our derived concentration-response function for HPEs to assess global HPE variations from 1990 to 2019, and to estimate the PM2.5-associated premature mortality during HPEs. Our results reveal that HPE frequency increased significantly globally. HPE PM2.5 intensity in the Global North continuously increased, overpassing the Global South after 2010, indicating a recurred risk of air pollution under climate change in the Global North after several years of emission control endeavors. Globally, we estimated approximately 694,440 (95% CI: 687,996–715,311) total mortalities associated with acute PM2.5 exposure during HPEs from 1990 to 2019, with the Global South accounting for around 80% of these deaths. Among the most vulnerable 15 countries, India had by far the highest mortality burden, and the United States, Russia, Japan, and Germany were particularly highlighted as having higher burdens within the Global North. Our findings highlight the importance of considering environmental inequality between the Global North and the Global South, and co-benefits of air pollution-climate change mitigation during policymaking processes.

在炎热和污染事件期间暴露于空气污染和过热可能在全球范围内协同造成更高的健康风险。然而,hpe的长期全球时空特征及其对健康的影响仍不清楚。在此,我们利用细颗粒物(PM2.5)和气候的再分析数据以及我们导出的HPE浓度响应函数进行了统计分析,以评估1990年至2019年全球HPE变化,并估计HPE期间PM2.5相关的过早死亡率。我们的研究结果表明,HPE频率在全球范围内显著增加。全球北方的HPE PM2.5强度持续增加,2010年后超过了全球南方,表明经过几年的排放控制,全球北方在气候变化下的空气污染风险再次出现。在全球范围内,我们估计,从1990年到2019年,HPEs期间与急性PM2.5暴露相关的总死亡人数约为694,440人(95% CI: 687,996-715,311),其中全球南方占这些死亡人数的80%左右。在最脆弱的15个国家中,印度的死亡率负担最高,而美国、俄罗斯、日本和德国在全球北方的负担尤其突出。我们的研究结果强调了在政策制定过程中考虑全球北方和全球南方之间的环境不平等以及空气污染-减缓气候变化的共同利益的重要性。
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引用次数: 0
Overexposed and Understudied: Environmental Risks Among Older Adults Experiencing Homelessness in Phoenix, Arizona 过度暴露和研究不足:亚利桑那州凤凰城老年人无家可归的环境风险
IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2025-05-12 DOI: 10.1029/2025GH001372
Zachary Van Tol, Ariane Middel, Jennifer K. Vanos, Kristin M. Ferguson

Individuals experiencing homelessness are highly vulnerable to urban environmental hazards, such as heat and air pollution, due to a lack of stable housing and limited access to indoor or cooled spaces. These risks are heightened for older adults and individuals with preexisting health conditions. With intensifying summer heat in the American Southwest and the persistence of urban homelessness, this study explores how older adults experiencing homelessness in Phoenix, Arizona perceive and interact with heat and air pollution as well as the adequacy of available coping resources and information. A survey was co-produced with community members with lived experience. A sub-group of community members assisted in proctoring the surveys among adults 55 and older at a downtown service agency. Survey results informed the location of data collection using MaRTy—a mobile biometeorological cart—and remotely sensed fine particulate matter (PM2.5). Findings reveal that heat and air pollution significantly influence travel decisions and contribute to health issues for many respondents. Midday and evening thermal radiation levels regularly exceeded safe thresholds, while PM2.5 concentrations often surpassed annual air quality guidelines, though they posed less acute health risks. Most participants reported awareness of health risks and employed strategies to reduce exposure. However, many expressed that city-level, public resources are insufficient to prevent heat- and air pollution-related health issues. Findings underscore the need for targeted interventions—such as better access to transportation and essential healthcare and extended hours of operation for service providers—to enhance resource accessibility and mitigate environmental health risks for vulnerable populations.

由于缺乏稳定的住房和进入室内或制冷空间的机会有限,无家可归者极易受到城市环境危害的影响,例如高温和空气污染。对于老年人和已有健康问题的个人,这些风险更高。随着美国西南部夏季高温的加剧和城市无家可归者的持续存在,本研究探讨了亚利桑那州凤凰城的老年人如何感知和互动高温和空气污染,以及可用的应对资源和信息的充分性。一项调查是与有生活经验的社区成员共同制作的。一个由社区成员组成的小组在市中心的一家服务机构协助监督调查,调查对象是55岁及以上的成年人。调查结果告知了使用移动生物气象车marty收集数据的地点,并遥感了细颗粒物(PM2.5)。调查结果显示,热和空气污染严重影响了许多受访者的旅行决定,并导致了健康问题。中午和晚上的热辐射水平经常超过安全阈值,而PM2.5浓度经常超过年度空气质量指南,尽管它们构成的健康风险不那么严重。大多数与会者报告了对健康风险的认识,并采取了减少接触的策略。然而,许多人表示,城市层面的公共资源不足以预防与高温和空气污染有关的健康问题。研究结果强调,需要采取有针对性的干预措施,如改善交通和基本医疗服务,延长服务提供者的营业时间,以提高资源可及性,减轻弱势群体的环境健康风险。
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引用次数: 0
Effect Modification of Temperature Variability on the Association Between Ambient Heat and Hospitalization: A Nationwide Study in Brazil Between 2000 and 2015 温度变化对环境热与住院之间关系的影响:2000 - 2015年巴西全国研究
IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2025-04-26 DOI: 10.1029/2024GH001284
Mengwei Zhuang, Yanwen Cao, Shanshan Li, Micheline S. Z. S. Coelho, Paulo H. N. Saldiva, Yuming Guo, Qi Zhao

Little evidence is available about how temperature variability (TV) may modify the association between ambient heat and health conditions, especially in less developed countries, for example, Brazil. This study explored the change in heat-hospitalization association from days with low to high temperature variabilities (TVs) in Brazil. We collected data on daily hospitalization and weather from 1,814 Brazilian cities during the 2000–2015 hot seasons. For each city, the heat-hospitalization association was estimated using the quasi-Poisson regression with constrained lag model on days with low and high TVs, respectively. City-specific effect estimates were then pooled using random-effect meta-analysis. Stratified analyses were performed by region, sex, age-group and cause category. Our results showed that at the national level the risk of hospitalization increased by 4.4% [95% confidence interval (CI): 4.0%–4.7%] and 2.7% (95%CI: 2.4%–3.0%) per 5°C increase in daily mean temperature on days with low and high TVs, respectively. The effect modification of TV on heat-hospitalization association was significant in the northeast, southeast and south, and for most population groups except for the children aged 0–4 years and the elderly aged ≥80 years. Significant effect modification of TV was observed in injury and poisoning, respiratory and cardiovascular diseases. Our findings suggest that in Brazil, the heat-health association is substantially modified by exposure to TV. The high heat susceptibility on the day with low TV warrants particular concern in order reducing the risk of disease burden.

关于温度变率(TV)如何改变环境热量与健康状况之间的关系,特别是在巴西等欠发达国家,几乎没有证据。本研究探讨了巴西从低温变率到高温变率(TVs)天数的热住院关联变化。我们收集了2000-2015年炎热季节1814个巴西城市的每日住院和天气数据。利用约束滞后模型拟泊松回归估计了各城市在低电视日和高电视日的热住院关联。然后使用随机效应荟萃分析汇总特定城市的效应估计。按地区、性别、年龄组和病因分类进行分层分析。结果显示,在全国范围内,低电视和高电视日平均气温每升高5°C,住院风险分别增加4.4%[95%可信区间(CI): 4.0%-4.7%]和2.7% (95%CI: 2.4%-3.0%)。电视对热住院关联的影响在东北、东南和南方地区均显著,除0 ~ 4岁儿童和≥80岁老年人外,其余人群均显著。改良TV对损伤中毒、呼吸系统及心血管疾病的治疗效果显著。我们的研究结果表明,在巴西,看电视大大改变了热健康的关系。为了减少疾病负担的风险,应特别关注低电视日的高热易感性。
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引用次数: 0
Heat Waves and Early Birth: Exploring Vulnerability by Individual- and Area-Level Factors 热浪与早产:通过个体和区域层面的因素探索脆弱性
IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2025-04-23 DOI: 10.1029/2025GH001348
A. Fitch, M. Huang, M. J. Strickland, A. J. Newman, C. Kalb, J. L. Warren, S. Kelley, X. Zheng, H. H. Chang, L. A. Darrow

Extreme heat has been linked to many health outcomes, including preterm and early term birth. We examine associations between acute heat wave exposure and risk of preterm (PTB) (28–36 weeks) or early term (ETB) (37–38 weeks) birth, stratified by individual-level and area-level factors. Daily ambient mean temperature was linked to maternal residence in state vital records for preterm and early term births in California, Florida, Georgia, Kansas, Nevada, New Jersey, North Carolina, and Oregon between 1990 and 2017. Heat waves were identified during the four-day exposure window preceding birth using the 97.5th percentile mean temperature for zip code tabulation areas (ZCTA). We used a time-stratified case-crossover design, restricted to the warm season (May through September) and stratified by maternal age, maternal education, ZCTA-level impervious land cover or social deprivation index. We pooled estimated odds ratios across states using inverse-variance weighting. The PTB and ETB analyses included up to 945,836 and 2,966,661 cases, respectively. Heat-related ETB risk was consistently highest among women <25 years of age, women with ≤high school education, and women living in areas of higher social deprivation and impervious land cover. PTB associations were also elevated in these subgroups, but positive associations were also observed among older, more educated mothers, and in areas with less social deprivation. Across all subgroups and outcomes, the change in odds associated with heat waves ranged from no increase to a 7.9% increase. Heat-related early term birth risk is enhanced among subgroups associated with socioeconomic disadvantage, but patterns of vulnerability were less consistent for preterm birth.

极端高温与许多健康结果有关,包括早产和早产。我们研究了急性热浪暴露与早产(PTB)(28-36周)或早产(ETB)(37-38周)出生风险之间的关系,并按个人水平和地区水平因素分层。1990年至2017年期间,加利福尼亚州、佛罗里达州、佐治亚州、堪萨斯州、内华达州、新泽西州、北卡罗来纳州和俄勒冈州早产儿和早产的州生命记录中,每日环境平均温度与孕产妇居住有关。使用邮政编码制表区域(ZCTA)的97.5%平均温度,在出产前四天暴露窗口中确定了热浪。我们采用了时间分层的病例交叉设计,限制在温暖季节(5月至9月),并根据母亲年龄、母亲教育程度、zcta水平的不透水土地覆盖或社会剥夺指数进行分层。我们使用反方差加权方法汇总了各州的估计比值比。PTB和ETB分析分别包括945,836例和29966,661例。与热相关的ETB风险在25岁以下的女性、高中以下教育程度的女性以及生活在社会剥夺程度较高和土地覆盖不透水地区的女性中始终最高。在这些亚组中,PTB的相关性也有所升高,但在年龄较大、受教育程度较高的母亲和社会剥夺程度较低的地区,也观察到呈正相关。在所有亚组和结果中,与热浪相关的几率变化从没有增加到增加7.9%不等。与高温相关的早产风险在与社会经济劣势相关的亚组中增加,但早产儿的脆弱性模式不太一致。
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引用次数: 0
Associations Between Temperature and Location of Injury or Condition Among Heat-Related Emergency Department Visits 在与热相关的急诊科就诊中,温度与受伤部位或状况之间的关系
IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2025-04-14 DOI: 10.1029/2024GH001287
Chen Li, Hua Hao, Morgan Lane, Noah Scovronick, Rebecca Zhang, Stefanie Ebelt, Howard H. Chang

High ambient temperature poses significant health risk globally. However, the relative importance of different exposure pathways leading to health risks remains unclear. For 9 US states during 2016–2018, ED visit records for heat exhaustion and heat stroke (HEAT), fluid and electrolyte imbalance (FEI), volume depletion (VD), and acute kidney injury (AKI) were identified via diagnosis codes. Co-diagnosed Y92 subcodes (Y codes) were used to categorize the patient's location at the time of injury or condition. Logistic regressions were used to estimate nonlinear associations between same-day temperature and Y codes for 11 non-residential versus residential locations among heat-related ED visits, including stratified analyses by patient age, race, and ethnicity. Odds ratios (OR) were calculated between the 95th versus 50th percentile of temperature. Overall, higher temperature was associated with increased risks of ED visits with Y codes for non-residential locations. HEAT ED visits were more likely to have Y codes for streets compared to residential locations (OR:1.68, 95% CI: 1.12–2.51). Similarly, VD visits were more likely to have Y codes for industrial area (OR: 2.68, 95% CI: 1.98–3.63), farms (OR:7.66, 95% CI: 4.05–14.50), recreation areas (OR:2.25, 95% CI: 1.78–2.84), and streets (OR:1.54, 95% CI: 1.39–1.70), but were less likely to have Y codes for public places (OR: 0.89, 95% CI: 0.84, 0.94). Similar associations were observed for FEI and AKI ED visits. Locations associated with higher heat risks may be due to exposure outdoor temperature and activities, supporting the need to develop strategies and interventions that minimize heat exposure in these areas.

高环境温度在全球范围内构成重大的健康风险。然而,导致健康风险的不同接触途径的相对重要性仍不清楚。在2016-2018年期间,美国9个州通过诊断代码确定了热衰竭和中暑(heat)、液体和电解质失衡(FEI)、容量耗尽(VD)和急性肾损伤(AKI)的急诊科就诊记录。使用共同诊断的Y92亚码(Y码)对患者在受伤或病情时的位置进行分类。在与热相关的急诊科就诊中,使用逻辑回归来估计11个非居住地点与居住地点的当日温度和Y代码之间的非线性关联,包括按患者年龄、种族和民族进行分层分析。计算95百分位和50百分位温度之间的比值比(OR)。总体而言,较高的温度与非住宅地区Y码ED就诊的风险增加有关。与居民区相比,热电科就诊更可能有街道Y代码(OR:1.68, 95% CI: 1.12-2.51)。同样,VD访问在工业区(OR: 2.68, 95% CI: 1.98-3.63)、农场(OR:7.66, 95% CI: 4.05-14.50)、娱乐区(OR:2.25, 95% CI: 1.78-2.84)和街道(OR:1.54, 95% CI: 1.39-1.70)中更有可能使用Y代码,但在公共场所(OR: 0.89, 95% CI: 0.84, 0.94)中使用Y代码的可能性较小。在FEI和AKI ED就诊中也观察到类似的关联。高温风险较高的地区可能是由于暴露在室外温度和活动中,因此需要制定策略和干预措施,以尽量减少这些地区的高温暴露。
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引用次数: 0
Effect of Short-Term Exposure to Ambient Temperatures on Parkinson's Diseases Mortality Among Elderly Aged 60 Years and Above in China, 2013–2020 2013-2020年短期环境温度暴露对中国60岁及以上老年人帕金森病死亡率的影响
IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2025-04-08 DOI: 10.1029/2024GH001246
Rui Zhang, Ainan Jia, Huan Zheng, Yonghong Li, Chaonan Wang, Siyuan Wu, Songwang Wang, Qing Guo, Yu Wang, Peng Bi, Jing Wu

Parkinson's disease (PD) is a prevalent neurodegenerative disorder with significant negative health and economic implications for individuals, families and society. This study utilized an individual-level time-stratified case-crossover study design to investigate the relationship between ambient temperatures and PD mortality among the elderly in China. A combination of conditional logistic regression and distributed lag non-linear model was employed to analyze the data, and the mortality burden attributed to ambient temperatures was quantified. The study included a total of 59,397 deceased PD patients aged 60 years and above who died between 2013 and 2020. Findings revealed that the effects of extremely low temperature (−1°C) could persist for up to 14 days, while the impacts of extremely high temperature (30°C) were acute and last for 4 days and showing a significant harvest effect. For the overall population, the high temperatures significantly increased the risk of death, where low temperature did not. A lag0-14 cumulative odds ratios (COR) of extremely low temperature compared to the reference temperature (15°C) was 1.024 (95% CI: 0.971, 1.080). The lag0-14 COR of extremely high temperature was 1.206 (95% CI: 1.116, 1.304). Additionally, high temperatures attributed greater AF of 4.013 (95% eCI: 1.990, 5.894) comparing to low temperatures did of 0.762 (95% eCI: −0.624, 2.017). Significant differences were found across regions. No statistically significant differences were found between the sex and age. This nationwide study provides evidence for tailored interventions in specific regions and populations to reduce temperature-related PD mortality among the elderly in China.

帕金森病(PD)是一种普遍存在的神经退行性疾病,对个人、家庭和社会具有显著的负面健康和经济影响。本研究采用个体水平时间分层病例交叉研究设计,探讨环境温度与中国老年人帕金森病死亡率之间的关系。采用条件logistic回归和分布滞后非线性模型相结合的方法对数据进行分析,量化环境温度导致的死亡负担。该研究共包括2013年至2020年间死亡的59397名60岁及以上的PD患者。结果表明,极低温(- 1°C)的影响可持续长达14天,而极高温(30°C)的影响是急性的,持续4天,并显示出显著的收获效果。对于总体人群来说,高温显著增加了死亡风险,而低温则没有。与参考温度(15°C)相比,极低温的lag0-14累积优势比(COR)为1.024 (95% CI: 0.971, 1.080)。极高温的lag0-14 COR为1.206 (95% CI: 1.116, 1.304)。此外,高温的AF值为4.013 (95% eCI: 1.990, 5.894),而低温的AF值为0.762 (95% eCI: - 0.624, 2.017)。不同地区之间存在显著差异。性别和年龄之间没有统计学上的显著差异。这项全国性的研究为针对特定地区和人群的针对性干预措施提供了证据,以降低中国老年人与温度相关的PD死亡率。
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