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Potential and limitations of naso-alveolar molding in patients with oral cleft 唇腭裂患者鼻牙槽成型的潜力和局限性
IF 2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-15 DOI: 10.1053/j.sodo.2025.09.011
R.V. Haddad , M. Saadeh , N. Abou Chebel , J.G. Ghafari
Naso-alveolar molding (NAM) has been promoted as a presurgical infant orthopedic adjunct procedure for cleft lip/palate (CL/P) to achieve improved lip closure and nasal symmetry.

Aim

to review current evidence on the benefits and practical limitations of NAM.

Results

NAM can reduce presurgical cleft severity by minimizing tissue tension during surgery, improve nasolabial form (notably nostril height, bialar width, and columellar length), and cut the need for early revisions. NAM is particularly indicated for wide unilateral and bilateral clefts. Complications are usually minor but frequent: soft-tissue irritation, intranasal inflammation, appliance instability, and parental burden for appliance management. Innovative modifications of the NAM appliance might lessen limitations.

Conclusion

NAM is an efficient orthopedic tool to improve surgical lip closure and nose form, especially with designs easily and correctly used by parents. Knowledge gaps and research priorities are identified.
鼻牙槽成型(NAM)已被推广为唇裂/腭裂(CL/P)的婴儿整形外科辅助手术,以实现改善的唇闭合和鼻对称。目的是回顾目前关于不结盟运动的益处和实际局限性的证据。结果通过减小术中组织张力,改善鼻唇形态(特别是鼻孔高度、双鼻翼宽度和小柱长度),减少早期修复的需要,可以降低手术前唇裂的严重程度。NAM特别适用于单侧和双侧宽唇裂。并发症通常轻微但频繁:软组织刺激,鼻内炎症,矫治器不稳定,以及父母管理矫治器的负担。NAM设备的创新修改可能会减少限制。结论nam是一种改善手术唇闭合和鼻形的有效矫形工具,其设计易于家长正确使用。确定了知识差距和研究重点。
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引用次数: 0
Early Secondary Alveolar Bone Grafting in Cleft Lip and Palate at 5 Years of Age: Clinical Rationale, Benefits, and Protocol 5岁唇腭裂早期继发性牙槽骨移植:临床原理、益处和方案
IF 2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-22 DOI: 10.1053/j.sodo.2025.08.007
Bruno Grollemund , Bieke kreps , Caroline Dissaux , Aurélie Majourau-Bouriez
Secondary alveolar bone grafting (SABG) is a cornerstone in the comprehensive management of patients with cleft lip and palate (CLP), essential for optimizing orthodontic outcomes and supporting esthetic and functional dental rehabilitation. While SABG has traditionally been performed between 9 and 11 years of age, an increasing number of multidisciplinary cleft teams, particularly in France, have adopted the Talmant protocol, which advocates for earlier grafting at 4 to 6 years of age. When performed prior to the eruption of permanent maxillary incisors and following orthodontic maxillary expansion when indicated, early SABG offers distinct advantages, including optimal surgical access, improved periodontal support, facilitated tooth eruption, and simplified orthodontic mechanics, without negatively impacting maxillary growth. However, specific challenges such as variable cooperation of younger patients, and considerations related to long term bone volume preservation in large clefts when permanent lateral incisors are congenitally missing must be acknowledged. This paper outlines the clinical rationale, indications, benefits, and limitations of early SABG and presents a detailed, patient-centered protocol built upon interdisciplinary collaboration between surgeons and orthodontists. Clinical cases are included to illustrate the protocol's practical implementation and long-term outcomes.
继发性牙槽骨移植(SABG)是唇腭裂(CLP)患者综合治疗的基石,对于优化正畸结果和支持牙齿美观和功能康复至关重要。虽然SABG传统上是在9至11岁之间进行的,但越来越多的多学科唇裂团队,特别是在法国,采用了Talmant方案,该方案主张在4至6岁时进行早期移植。如果在上颌恒切牙出牙之前进行,并在指征时进行正畸上颌扩张,早期SABG具有明显的优势,包括最佳手术通道,改善牙周支持,促进牙齿出牙,简化正畸力学,而不会对上颌生长产生负面影响。然而,具体的挑战,如年轻患者的可变合作,以及考虑到当永久侧切牙先天性缺失时,大裂的长期骨体积保存必须得到承认。本文概述了早期SABG的临床原理、适应症、益处和局限性,并提出了一个详细的、以患者为中心的方案,建立在外科医生和正畸医生之间跨学科合作的基础上。包括临床病例,以说明该方案的实际实施和长期结果。
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引用次数: 0
Obstructive sleep apnea and upper airway morphophysiology in orofacial clefts 腭裂患者阻塞性睡眠呼吸暂停与上呼吸道形态生理的关系
IF 2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-20 DOI: 10.1053/j.sodo.2025.08.005
Ivy Kiemle Trindade-Suedam , Thiago Henrique dos Santos Antunes Albertassi , Marcela Cristina Garnica-Siqueira , Sergio Henrique Kiemle Trindade

Objectives

This review aimed to synthesize evidence on the anatomical and functional characteristics of the upper airway in individuals with cleft lip and palate (CLP), explore how alterations relates to occurrence of obstructive sleep apnea (OSA), and examined the efficacy and clinical applicability of diagnostic and therapeutic strategies, focusing on implications for interdisciplinary clinical practice.

Methods

This critical narrative review was conducted using a literature search performed between April and May 2025 in the databases PubMed, Scopus, and Embase. Studies published from 2020 to 2025 were prioritized, and earlier references were included to provide essential conceptual or methodological background. Main descriptors and keywords included: Obstructive Sleep Apnea, Cleft Lip, Cleft Palate, Upper Airways, Craniofacial Morphology, Cone-Beam Computed Tomography (CBCT), Computational Fluid Dynamics (CFD), and Polysomnography.

Results

Individuals with CLP often present reduced airway volume and increased risk for OSA. Anatomical changes increase airflow resistance; however, surgical interventions such as orthopedic maxillary expansion and orthognathic surgery may improve airway dimensions and sleep quality. Combining clinical assessment, CBCT, CFD, and polysomnography allows for an overall evaluation of individuals.

Conclusion

Management of OSA should be integrated into the craniofacial rehabilitation protocol for individuals with CLP and other craniofacial anomalies. Emerging technologies, such as digital sleep monitoring combined with artificial intelligence and assessment of upper airway dimensions, support early diagnosis, risk stratification, and the development of individualized therapeutic strategies.
目的本综述旨在综合唇腭裂(CLP)患者上气道解剖和功能特征的证据,探讨其改变与阻塞性睡眠呼吸暂停(OSA)发生的关系,并检查诊断和治疗策略的疗效和临床适用性,重点关注跨学科临床实践的意义。方法采用PubMed、Scopus和Embase数据库于2025年4月至5月间进行的文献检索进行批判性叙述性综述。优先考虑2020年至2025年发表的研究,并包括较早的参考文献,以提供必要的概念或方法背景。主要描述词和关键词包括:阻塞性睡眠呼吸暂停、唇裂、腭裂、上呼吸道、颅面形态学、锥束计算机断层扫描(CBCT)、计算流体动力学(CFD)和多导睡眠图。结果CLP患者通常表现为气道体积减小,阻塞性睡眠呼吸暂停的风险增加。解剖改变增加气流阻力;然而,外科干预,如矫形上颌扩张和正颌手术可能改善气道尺寸和睡眠质量。结合临床评估、CBCT、CFD和多导睡眠图,可以对个体进行全面评估。结论对于CLP及其他颅面异常患者,应将OSA的治疗纳入颅面康复方案。新兴技术,如结合人工智能和上呼吸道维度评估的数字睡眠监测,支持早期诊断、风险分层和个性化治疗策略的发展。
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引用次数: 0
Balancing benefits and risks: Analyzing the short-term and long-term effects of presurgical infant orthopedic (PSIO) treatment in UCLP patients 平衡收益与风险:分析UCLP患者术前婴儿骨科(PSIO)治疗的短期和长期效果
IF 2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-19 DOI: 10.1053/j.sodo.2025.08.004
Puneet Batra , Aditya Talwar , Isha Duggal
Cleft lip and palate (CLP) are among the most common congenital craniofacial anomalies, presenting functional and aesthetic challenges that require a multidisciplinary treatment approach from infancy through adulthood. Presurgical infant orthopaedics (PSIO) are the early nonsurgical alveolar molding techniques to guide the growth and alignment of the maxillary segments before primary surgical repair, using appliances or taping techniques to improve cleft morphology and assist in lip repair.
The current review describes the development of PSIO in the early treatment of patients with cleft lip and palate anomaly, highlighting both its potential advantages and concerns. PSIO has been shown to facilitate surgical repair, improve nasal symmetry, columella lengthening, improve alveolar segments, and decrease the need for secondary surgical procedures. However, in addition to the continuous discussions about its effectiveness, there are still concerns with compliance, cost, and outcome variability, especially with the long-term effects of PSIO on speech development, facial growth, and psychosocial outcomes being debatable.
The present article enumerates contemporary practices and emerging trends, emphasizing the need for standardized protocols and robust evidence elaborating on the impact of PSIOs on facial growth, speech development, and psychosocial well-being. Ultimately, providing a balanced synthesis of current knowledge and outline future directions for individualized approaches supported by advances in digital technologies and personalized care to optimize treatment strategies in patients with cleft lip and palate.
唇腭裂(CLP)是最常见的先天性颅面畸形之一,表现出功能和美学上的挑战,需要从婴儿期到成年期的多学科治疗方法。手术前婴儿矫形术(PSIO)是早期的非手术牙槽成型技术,用于在初次手术修复前指导上颌节段的生长和排列,使用矫治器或胶带技术来改善唇裂形态并协助唇部修复。本文综述了PSIO在早期治疗唇腭裂患者中的发展,强调了其潜在的优势和值得关注的问题。PSIO已被证明可以促进手术修复,改善鼻对称性,延长鼻小柱,改善肺泡节段,减少二次手术的需要。然而,除了对其有效性的持续讨论之外,仍存在对依从性,成本和结果可变性的担忧,特别是PSIO对语言发育,面部生长和心理社会结果的长期影响存在争议。本文列举了当代实践和新兴趋势,强调需要标准化的协议和强有力的证据来阐述psio对面部生长、语言发育和社会心理健康的影响。最终,在数字技术和个性化护理进步的支持下,提供当前知识的平衡综合和概述个性化方法的未来方向,以优化唇腭裂患者的治疗策略。
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引用次数: 0
Evidence based orthodontics – a narrative roadmap for contemporary clinical practise cleft lip and palate 基于证据的正畸-当代唇腭裂临床实践的叙事路线图
IF 2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-17 DOI: 10.1053/j.sodo.2025.08.006
Agneta Linder Aronson Karsten
To give birth to a child with a cleft of the lip, alveolus and/or palate is for many parents unexpected and the parents will experience different feelings the first days after delivery. Therefore, it is important that the medical and dental proffessions have evidence based treatments to offer. In many countries it is up to the parents to seek for information and treatments, whereas in other countries, there are multidisciplinary teams taking care of the planning, surgical reconstructions and other treatments eg. orthodontics from birth till adulthood. The goals for these teams are that the child breathes, eats, speaks, and feels well, have good craiofacial growth, a functional occlusion, a nice smile and a good self-esteem.
对于许多父母来说,生下一个唇裂、肺泡和/或腭裂的孩子是出乎意料的,父母在分娩后的第一天会有不同的感受。因此,医学和牙科专业提供基于证据的治疗是很重要的。在许多国家,寻求信息和治疗取决于父母,而在其他国家,有多学科团队负责计划,手术重建和其他治疗。从出生到成年的牙齿矫正。这些小组的目标是孩子呼吸,吃饭,说话,感觉良好,颅面发育良好,功能闭塞,笑容灿烂,自尊心强。
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引用次数: 0
FMii --- Table of Contents FMii——目录表
IF 2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-13 DOI: 10.1053/S1073-8746(25)00076-3
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引用次数: 0
Future Issues 未来的问题
IF 2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-13 DOI: 10.1053/S1073-8746(25)00077-5
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引用次数: 0
FMi --- Ed Board FMi——教育局
IF 2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-13 DOI: 10.1053/S1073-8746(25)00075-1
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引用次数: 0
Association between the vertical position of the inferior turbinate and alveolar bone bridge morphology after secondary alveolar bone grafting in patients with unilateral cleft lip and palate: A retrospective study 单侧唇腭裂患者二次牙槽骨移植后下鼻甲垂直位置与牙槽骨桥形态的关系:回顾性研究
IF 2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-07 DOI: 10.1053/j.sodo.2025.07.015
Masayoshi Uezono , Shiori Okubo , Takuya Ogawa , Keiji Moriyama
This study aimed to investigate the relationship between the degree of inferior turbinate descent (ITD), the width of the alveolar cleft (WAC) prior to secondary alveolar bone grafting (SABG), and the concavity of the alveolar bone bridge on the nasal side (CAB) in patients with unilateral cleft lip and palate (UCLP). The study included fourteen patients (seven males and seven females) who underwent SABG between the age of 8 and 11 years. One patient also underwent partial inferior turbinectomy (PIT) during SABG. Pre- and postoperative posteroanterior cephalograms were used to evaluate ITD and CAB. Additionally, in seven cases, WAC was measured using reconstructed computed tomography images taken before SABG. Scatter plot analysis was performed to examine the relationships among ITD, CAB, and WAC, and Spearman’s correlation test was used for statistical analysis. A significant correlation was observed between the ITD and CAB (p < 0.01). Furthermore, the scatter plots indicated that the depression on the bone bridge was reduced in the patients who underwent PIT. These findings suggest that a lower vertical position of the inferior turbinate may contribute to increased concavity of the nasal side of the alveolar bone bridge following SABG in patients with UCLP.
本研究旨在探讨单侧唇腭裂(UCLP)患者继发性牙槽骨移植(SABG)前下鼻甲下降程度(ITD)、牙槽骨裂宽度(WAC)与鼻侧牙槽骨桥凹度(CAB)的关系。该研究包括14名患者(7男7女),他们在8至11岁之间接受了SABG。一位患者在SABG期间也接受了部分下鼻甲切除术(PIT)。术前和术后后脑前位造影用于评估ITD和CAB。此外,在7例中,WAC是通过SABG前重建的计算机断层扫描图像来测量的。采用散点图分析检验ITD、CAB和WAC之间的关系,采用Spearman相关检验进行统计分析。ITD与CAB之间存在显著相关性(p < 0.01)。此外,散点图显示,接受PIT的患者骨桥上的凹陷减少。这些结果表明,下鼻甲较低的垂直位置可能导致UCLP患者SABG后牙槽骨桥鼻侧凹度增加。
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引用次数: 0
Anteroposterior orthopedic management of maxillary deficiencies in patients with cleft lip and palate: treatment based on timing, indications and severity 唇腭裂患者上颌缺损的前后位矫形治疗:基于时机、适应症和严重程度的治疗
IF 2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-08-05 DOI: 10.1053/j.sodo.2025.07.011
Maria Costanza Meazzini
Early correction of maxillary hypoplasia in cleft lip and palate (CLP) patients is followed by major recurrence; therefore, maxillary protraction in the deciduous/early mixed dentition should be carried out mainly if significant functional problems are associated. On the contrary, long-term results of protraction applied close to growth peak, are more stable.
We describe our clinical approach using 3 subgroups. Group 1) Early treatment: 23 CLP patients affected by middle ear infection and hearing impairment were treated at an average age of 7.9 years with expansion and protraction face mask and compared to an age matched control. Audiometric tests and tympanograms improved in 82 % of the sample. Group 2) Adolescents with moderate-severe hypoplasia (<7 mm): 31 UCLP patients were treated with a Modified Alternate Rapid Maxillary Expantion and Constriction (Alt-Ramec) technique, at an average age of 12.5 years. Patients had adequate alveolar ossification, either after early secondary periosteoplasty or secondary alveolar bone grafting. The maxilla advanced 5.5 ± 2.3 mm and was stable in the long term (20.3 years). Group3) Adolescents with extremely severe hypoplasia (>8–10 mm): Thirteen very severe patients were treated with MART and traction with a Rigid External Distraction device (RED) for sutural protraction at an average age of 11.3 years. A-point advanced 16.4 ± 8.2 mm. Patients were followed short term for an average of 1.6 ± 0.8 years.
唇腭裂(CLP)患者上颌发育不全早期矫治后主要复发;因此,在乳牙/早期混合牙列中,如果伴有明显的功能问题,应主要进行上颌牵引。相反,在接近生长高峰时长期施用催肥效果更稳定。我们用3个亚组来描述我们的临床方法。早期治疗:23例伴有中耳感染和听力障碍的CLP患者,平均年龄7.9岁,使用扩张和拉伸面罩治疗,并与年龄匹配的对照组进行比较。听力测试和鼓室图改善了82%的样本。组2)青少年中重度发育不全(< 7mm): 31例UCLP患者采用改良的交替快速上颌扩张和收缩(Alt-Ramec)技术治疗,平均年龄12.5岁。患者在早期继发性骨膜成形术或继发性牙槽骨移植后均有足够的牙槽骨骨化。上颌向前移动5.5±2.3 mm,长期稳定(20.3年)。组3)青少年极重度发育不全(> 8-10 mm): 13例极重度患者,平均年龄11.3岁,采用MART联合硬外牵开器(RED)牵引进行缝线牵拉。a点超前16.4±8.2 mm。短期随访平均为1.6±0.8年。
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引用次数: 0
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Seminars in Orthodontics
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