首页 > 最新文献

Bioinspired Biomimetic and Nanobiomaterials最新文献

英文 中文
The synthesis of oxalate-modified pyrite/chitosan as antibacterial composite 草酸改性黄铁矿/壳聚糖抗菌复合材料的合成
4区 工程技术 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-05-22 DOI: 10.1680/jbibn.22.00022
Rashween Kaur Jagjit Singh, Khee Chung Hui, N. A. M. Salleh, Prakash Peechmani, F. Aziz, H. Abdullah, A. N. Rosli, N. S. Sambudi
The combination of organic and inorganic components has produced bioactive materials with excellent properties. Chitosan is a widely used organic component, which has received recognition as biocompatible material. On the other hand, naturally occurred pyrite so far received limited exposure as biomaterial, despite its great antibacterial activity. Hence, the incorporation of pyrite in chitosan matrix is expected to highlight the usage of pyrite as bioactive material, especially in antibacterial response. In this research, chitosan and oxalate-modified pyrite was combined to form beads at wt% pyrite loading of 1%, 3%, and 5%. The EDX analysis could confirm the loading of pyrite in the bead’s matrix. The beads exhibit high water absorption ability, with addition of pyrite could increase the absorption of water up to 37% compared to blank chitosan beads. The immersion of beads in simulated body fluid shows the bioactivity of beads by formation of apatite. Microbial activity against E. coli and S. aureus is exhibited for all composite beads containing oxalate-modified pyrite, especially for beads containing 5 wt% oxalate-pyrite.
有机和无机成分的结合产生了具有优异性能的生物活性材料。壳聚糖是一种应用广泛的有机成分,已被公认为具有生物相容性的材料。另一方面,尽管天然存在的黄铁矿具有很强的抗菌活性,但迄今为止,它作为生物材料的暴露量有限。因此,将黄铁矿掺入壳聚糖基质有望突出黄铁矿作为生物活性材料的用途,尤其是在抗菌反应中。在本研究中,壳聚糖和草酸盐改性的黄铁矿在黄铁矿负载量为1%、3%和5%的情况下结合形成珠粒。EDX分析可以证实黄铁矿在珠粒基质中的负载量。与空白壳聚糖珠粒相比,添加黄铁矿可使珠粒的吸水率提高37%。将珠子浸入模拟体液中显示了珠子通过形成磷灰石而具有的生物活性。所有含有草酸改性黄铁矿的复合珠粒都表现出对大肠杆菌和金黄色葡萄球菌的微生物活性,尤其是含有5 wt%草酸盐黄铁矿。
{"title":"The synthesis of oxalate-modified pyrite/chitosan as antibacterial composite","authors":"Rashween Kaur Jagjit Singh, Khee Chung Hui, N. A. M. Salleh, Prakash Peechmani, F. Aziz, H. Abdullah, A. N. Rosli, N. S. Sambudi","doi":"10.1680/jbibn.22.00022","DOIUrl":"https://doi.org/10.1680/jbibn.22.00022","url":null,"abstract":"The combination of organic and inorganic components has produced bioactive materials with excellent properties. Chitosan is a widely used organic component, which has received recognition as biocompatible material. On the other hand, naturally occurred pyrite so far received limited exposure as biomaterial, despite its great antibacterial activity. Hence, the incorporation of pyrite in chitosan matrix is expected to highlight the usage of pyrite as bioactive material, especially in antibacterial response. In this research, chitosan and oxalate-modified pyrite was combined to form beads at wt% pyrite loading of 1%, 3%, and 5%. The EDX analysis could confirm the loading of pyrite in the bead’s matrix. The beads exhibit high water absorption ability, with addition of pyrite could increase the absorption of water up to 37% compared to blank chitosan beads. The immersion of beads in simulated body fluid shows the bioactivity of beads by formation of apatite. Microbial activity against E. coli and S. aureus is exhibited for all composite beads containing oxalate-modified pyrite, especially for beads containing 5 wt% oxalate-pyrite.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48888233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allium cepa-based zinc oxide nanoparticles: synthesis, characterization and biochemical potentials 韭菜基氧化锌纳米颗粒:合成、表征和生化势
4区 工程技术 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-05-18 DOI: 10.1680/jbibn.22.00038
Sheeza Masud, H. Munir, M. Irfan, M. Tayyab
In this research work, the Allium cepa (AC)bulb-based zinc oxide nanoparticles (ZnO-NPs) were prepared successfully through a green synthesis approach. Phytocompounds present in the Allium cepa bulb successfully reduced and stabilized the Zn+2 ions into ZnO-NPs. Synthesis of the liquid form (L-ZnO-NPs) and calcined form (C-ZnO-NPs) were carried out. The color change of nanoparticles (NPs) colloidal solution from transparent to yellow, the surface plasmon resonance (SPR) peaks by UV-Visible spectroscopic analyses at 350 nm and 370 nm and Infrared spectrum shown functional groups below 700 nm, confirmed the synthesis of ZnO-NPs. The elemental composition of NPs revealed that the molecular weight of Zinc was 66 % and 61 % while Oxygen was 24 % and 26 % respectively in C-ZnO-NPs and L-ZnO-NPs. The scanning electron microscopy and X-ray diffraction pattern confirmed the successful synthesis of rod-shaped, crystalline ZnO-NPs (30-35 nm) with uniform distribution. The 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay-based antioxidant potential of C-ZnO-NPs and L-ZnO-NPs were recorded as 72 % and 65 % inhibition respectively while hydrogen peroxide (H2O2) radical scavenging assays revealed 62 % and 48 % inhibition respectively at 75 µL concentration. ZnO-NPs showed good antimicrobial, in-vitro anti-diabetic and antioxidant potential. Hence, Allium cepa bulb based ZnO-NPs through a green chemistry approach can be considered an innovative addition to the science of free radical scavenging, diabetes, and microbial infection management.
在本研究工作中,通过绿色合成方法成功制备了洋葱(AC)球基氧化锌纳米颗粒(ZnO NPs)。洋葱鳞茎中存在的植物化合物成功地将Zn+2离子还原并稳定为ZnO NP。进行了液体形式(L-ZnO-NPs)和煅烧形式(C-ZnO-NP)的合成。纳米颗粒(NPs)胶体溶液从透明到黄色的颜色变化,表面等离子体共振(SPR)在350下通过紫外可见光谱分析达到峰值 nm和370 nm和红外光谱显示官能团低于700 nm的波长证实了ZnO NPs的合成。NP的元素组成显示,在C-ZnO-NP和L-ZnO-NP中,锌的分子量分别为66%和61%,而氧的分子量则分别为24%和26%。扫描电子显微镜和X射线衍射图证实了棒状晶体ZnO NPs(30-35 nm),分布均匀。基于2,2-二苯基-1-苦基肼(DPPH)测定的C-ZnO-NP和L-ZnO-NP的抗氧化潜力分别被记录为72%和65%的抑制,而过氧化氢(H2O2)自由基清除测定显示,在75 µL浓度。ZnO纳米粒子显示出良好的抗菌、体外抗糖尿病和抗氧化潜力。因此,通过绿色化学方法,洋葱球基ZnO纳米颗粒可以被认为是自由基清除、糖尿病和微生物感染管理科学的创新补充。
{"title":"Allium cepa-based zinc oxide nanoparticles: synthesis, characterization and biochemical potentials","authors":"Sheeza Masud, H. Munir, M. Irfan, M. Tayyab","doi":"10.1680/jbibn.22.00038","DOIUrl":"https://doi.org/10.1680/jbibn.22.00038","url":null,"abstract":"In this research work, the Allium cepa (AC)bulb-based zinc oxide nanoparticles (ZnO-NPs) were prepared successfully through a green synthesis approach. Phytocompounds present in the Allium cepa bulb successfully reduced and stabilized the Zn+2 ions into ZnO-NPs. Synthesis of the liquid form (L-ZnO-NPs) and calcined form (C-ZnO-NPs) were carried out. The color change of nanoparticles (NPs) colloidal solution from transparent to yellow, the surface plasmon resonance (SPR) peaks by UV-Visible spectroscopic analyses at 350 nm and 370 nm and Infrared spectrum shown functional groups below 700 nm, confirmed the synthesis of ZnO-NPs. The elemental composition of NPs revealed that the molecular weight of Zinc was 66 % and 61 % while Oxygen was 24 % and 26 % respectively in C-ZnO-NPs and L-ZnO-NPs. The scanning electron microscopy and X-ray diffraction pattern confirmed the successful synthesis of rod-shaped, crystalline ZnO-NPs (30-35 nm) with uniform distribution. The 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay-based antioxidant potential of C-ZnO-NPs and L-ZnO-NPs were recorded as 72 % and 65 % inhibition respectively while hydrogen peroxide (H2O2) radical scavenging assays revealed 62 % and 48 % inhibition respectively at 75 µL concentration. ZnO-NPs showed good antimicrobial, in-vitro anti-diabetic and antioxidant potential. Hence, Allium cepa bulb based ZnO-NPs through a green chemistry approach can be considered an innovative addition to the science of free radical scavenging, diabetes, and microbial infection management.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45374188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Attaching mechanism of dandelion seeds: results from morphology/structure and abscission force/angle 蒲公英种子的附着机制:形态/结构和脱落力/角度的结果
4区 工程技术 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-03-20 DOI: 10.1680/jbibn.22.00061
Lixin Wang, Guangshun Liu, Shan-yin Li
Mature dandelion seeds can be easily abscised from their capitulum by a tiny vibration or a gentle wind, and the previous study has revealed their abscission mechanism, but the mechanism governing the attachment of immature dandelion seeds is still unclear. This paper aims to uncover the attaching mechanism by morphology/structure analysis and abscission force/angle measurement. Connecting region of the immature dandelion seeds consists of upper barbs from neighboring achenes, lower barbs of achene and their groove in capitulum. The upper barbs have hierarchical structures that form barb-barb interlock, the lower barbs and their groove produce barbs-groove wrapping, together endow the dandelion seeds with a firm attachment (abscission force >155.9 mN). The firm attachment weakens sharply with the growth of dandelion seeds, which attributes to the considerable changes in morphology/structure, showing the remarkable decrease of abscission angle (critical opened stage 37.1 ± 5.2°, full opened stage 11.6 ± 3.0°) and the tiny abscission force (10.67–0.35 mN). The results reveal the attaching mechanism of immature dandelion seeds, and may inspire some novel biomimetic designs for the controllable attachment/abscission materials.
成熟的蒲公英种子可以很容易地通过微小的振动或微风从其头状花序脱落,先前的研究已经揭示了其脱落机制,但控制未成熟蒲公英种子附着的机制尚不清楚。本文旨在通过形态/结构分析和脱落力/角度测量揭示附着机理。未成熟蒲公英种子的连接区由相邻瘦果的上倒刺、瘦果的下倒刺及其在头状花序中的凹槽组成。上部倒钩具有层次结构,形成倒钩-倒钩互锁,下部倒钩及其凹槽产生倒钩-凹槽包裹,共同赋予蒲公英种子牢固的附着(脱落力>155.9 mN)。随着蒲公英种子的生长,牢固的附着性急剧减弱,这归因于形态/结构的显著变化,表现为脱落角(临界开放期37.1±5.2°,全开期11.6±3.0°)和微小脱落力(10.67–0.35 mN)。研究结果揭示了未成熟蒲公英种子的附着机制,并可能为可控附着/脱落材料的仿生设计提供启示。
{"title":"Attaching mechanism of dandelion seeds: results from morphology/structure and abscission force/angle","authors":"Lixin Wang, Guangshun Liu, Shan-yin Li","doi":"10.1680/jbibn.22.00061","DOIUrl":"https://doi.org/10.1680/jbibn.22.00061","url":null,"abstract":"Mature dandelion seeds can be easily abscised from their capitulum by a tiny vibration or a gentle wind, and the previous study has revealed their abscission mechanism, but the mechanism governing the attachment of immature dandelion seeds is still unclear. This paper aims to uncover the attaching mechanism by morphology/structure analysis and abscission force/angle measurement. Connecting region of the immature dandelion seeds consists of upper barbs from neighboring achenes, lower barbs of achene and their groove in capitulum. The upper barbs have hierarchical structures that form barb-barb interlock, the lower barbs and their groove produce barbs-groove wrapping, together endow the dandelion seeds with a firm attachment (abscission force >155.9 mN). The firm attachment weakens sharply with the growth of dandelion seeds, which attributes to the considerable changes in morphology/structure, showing the remarkable decrease of abscission angle (critical opened stage 37.1 ± 5.2°, full opened stage 11.6 ± 3.0°) and the tiny abscission force (10.67–0.35 mN). The results reveal the attaching mechanism of immature dandelion seeds, and may inspire some novel biomimetic designs for the controllable attachment/abscission materials.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41890035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation methods of biomimetic development: how can we compare and select topics? 仿生发展的评价方法:我们如何比较和选择主题?
4区 工程技术 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-03-20 DOI: 10.1680/jbibn.22.00070
Satoru Tachibana, Ryozo Noguchi, J. Miyasaka, K. Ohdoi
Biomimetics is a technology that utilises biological structures for manufacturing, and is attracting attention globally in a wide range of fields. However, there are challenges in sharing and communicating development between researchers with different specialties. Biomimetic developments have conventionally been expressed in terms of unique or unconnected indicators, which makes it difficult to understand for outsiders and compare different topics. In this study, evaluation guidelines were developed to effectively share and compare. As the method is directly related to actual development, it is a new methodological framework used in the target-setting phase. Several indicators and criteria with both biology and engineering were set up, proposing ways of evaluating and expressing development topics. And, actual evaluations and comparison were performed on several examples. This study discusses the possible outcomes from the evaluated results, the applied use and the challenges of the evaluation method. A major advancement came with the use of composite indicators to evaluate results, which can be easily compared with other topics. It is expected to contribute to smoother communication and process, and to support decisions on the direction of development.
仿生学是一种利用生物结构进行制造的技术,在全球范围内引起了广泛的关注。然而,在不同专业的研究人员之间分享和交流发展存在挑战。仿生学的发展通常用独特或不相关的指标来表示,这使得局外人难以理解和比较不同的主题。在本研究中,评估指南的制定是为了有效地分享和比较。该方法与实际开发直接相关,是在目标设定阶段使用的一种新的方法框架。建立了生物与工程结合的若干指标和标准,提出了评价和表达发展主题的方法。并对若干实例进行了实际评价和比较。本文讨论了评价结果可能产生的结果、评价方法的应用和面临的挑战。一个主要的进步是使用复合指标来评估结果,这可以很容易地与其他主题进行比较。预计它将有助于更顺畅的沟通和进程,并支持关于发展方向的决定。
{"title":"Evaluation methods of biomimetic development: how can we compare and select topics?","authors":"Satoru Tachibana, Ryozo Noguchi, J. Miyasaka, K. Ohdoi","doi":"10.1680/jbibn.22.00070","DOIUrl":"https://doi.org/10.1680/jbibn.22.00070","url":null,"abstract":"Biomimetics is a technology that utilises biological structures for manufacturing, and is attracting attention globally in a wide range of fields. However, there are challenges in sharing and communicating development between researchers with different specialties. Biomimetic developments have conventionally been expressed in terms of unique or unconnected indicators, which makes it difficult to understand for outsiders and compare different topics. In this study, evaluation guidelines were developed to effectively share and compare. As the method is directly related to actual development, it is a new methodological framework used in the target-setting phase. Several indicators and criteria with both biology and engineering were set up, proposing ways of evaluating and expressing development topics. And, actual evaluations and comparison were performed on several examples. This study discusses the possible outcomes from the evaluated results, the applied use and the challenges of the evaluation method. A major advancement came with the use of composite indicators to evaluate results, which can be easily compared with other topics. It is expected to contribute to smoother communication and process, and to support decisions on the direction of development.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41688225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing of teeth remineralization by electric field aid (in vitro study) 电场辅助增强牙齿再矿化(体外研究)
4区 工程技术 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-03-16 DOI: 10.1680/jbibn.22.00042
A. Khalil, A. El-Khatib, Rasha M. Hamouda, Sonia M Elshabrawy, S. Kandil
One of the major challenges in teeth re-mineralization is the slow rate of mineralization. In this paper, we developed electric field-aided mineralization system for rapidly regenerating teeth-like structure rapidly. The efficacy of application of electric field combined with Nano-chitosan gel, casein phosphopeptide amorphous calcium phosphate gel and their mixture was investigated as re-mineralizing accelerator for artificially demineralized teeth. Teeth samples have been demineralized by using ethylenediaminetetraacetic acid and subsequently subjected to each gel alone and combined with electric field (20 mA- 5 min). The structural analyses of teeth samples were examined by using scanning electron microscope and X-ray diffraction patterns and its hardness was obtained by Vickers micro-hardness test. The results revealed that the addition of chitosan to casein phosphopeptide amorphous calcium phosphate enhanced the re-mineralization of the tooth structure rather than each one individually. Furthermore, the application of electric field has enhanced teeth hardness and showed highest rate of re-mineralization. In conclusion, the proposed technique could be safely used to reduce the consuming time taken in re-mineralization and efficiently it may be used to increase tooth quality. It is suggested to study other biophysical parameters of using electric fields for in vivo applications.
牙齿再矿化的主要挑战之一是矿化速率缓慢。本文开发了一种用于快速再生齿状结构的电场辅助矿化系统。研究了电场与纳米壳聚糖凝胶、酪蛋白磷酸肽无定形磷酸钙凝胶及其混合物联合应用作为人工脱矿牙齿再矿化促进剂的效果。牙齿样品已通过使用乙二胺四乙酸进行脱盐,随后单独对每个凝胶进行处理并与电场(20 毫安-5 分钟)。用扫描电子显微镜和X射线衍射图对牙齿样品进行了结构分析,并用维氏显微硬度计测定了其硬度。结果表明,在酪蛋白磷酸肽无定形磷酸钙中加入壳聚糖,可以促进牙齿结构的再矿化,而不是单独矿化。此外,电场的应用提高了牙齿硬度,并显示出最高的再矿化率。总之,所提出的技术可以安全地用于减少再矿化所花费的时间,并且可以有效地用于提高牙齿质量。建议研究使用电场进行体内应用的其他生物物理参数。
{"title":"Enhancing of teeth remineralization by electric field aid (in vitro study)","authors":"A. Khalil, A. El-Khatib, Rasha M. Hamouda, Sonia M Elshabrawy, S. Kandil","doi":"10.1680/jbibn.22.00042","DOIUrl":"https://doi.org/10.1680/jbibn.22.00042","url":null,"abstract":"One of the major challenges in teeth re-mineralization is the slow rate of mineralization. In this paper, we developed electric field-aided mineralization system for rapidly regenerating teeth-like structure rapidly. The efficacy of application of electric field combined with Nano-chitosan gel, casein phosphopeptide amorphous calcium phosphate gel and their mixture was investigated as re-mineralizing accelerator for artificially demineralized teeth. Teeth samples have been demineralized by using ethylenediaminetetraacetic acid and subsequently subjected to each gel alone and combined with electric field (20 mA- 5 min). The structural analyses of teeth samples were examined by using scanning electron microscope and X-ray diffraction patterns and its hardness was obtained by Vickers micro-hardness test. The results revealed that the addition of chitosan to casein phosphopeptide amorphous calcium phosphate enhanced the re-mineralization of the tooth structure rather than each one individually. Furthermore, the application of electric field has enhanced teeth hardness and showed highest rate of re-mineralization. In conclusion, the proposed technique could be safely used to reduce the consuming time taken in re-mineralization and efficiently it may be used to increase tooth quality. It is suggested to study other biophysical parameters of using electric fields for in vivo applications.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48074468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The mechanical implementations in three kinds of color-changing beetle elytra 三种变色甲虫鞘翅的机械实现
4区 工程技术 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-02-28 DOI: 10.1680/jbibn.22.00074
Wei Wu, Yueming Wang, Jiyu Sun
With superior adaptability, some elytron as modified forewing can perform mechanical protection for underlying hindwing and soft body while conduct color-changing in dynamically natural environment. There are mainly three color-changing styles of angle dependence, irreversible and reversible color-changing for elytra. Here, Popillia indgigonacea Motsch, Sagra femorata purpurea Lichtenstein and Dynastes tityus were chosen to investigate the relationship between color formation of three color-changing styles and mechanical properties of light weight and high strength. The optical and nanomechanical properties of purplish red S. f. p. Lichtenstein were obtained through angle-resolved spectroscopy system and nanoindenter, respectively. In finite element analysis, three geometrical structure models of color-changing relevant, irrelevant and the whole elytron models were designed, and then mechanical properties of six coupled bionic models of each beetle were investigated. The multilayer, convex closures and photonic crystal in the epicuticle can complete the dynamic presentation of structural colors by interference, scattering and photonic band gap when resourcefully resist external forces in low/high stress and strain with high/small elastic modulus and hardness. Meanwhile, other microstructures of multilayer and trabecular hollow are reasonably constructed to cooperatively display mechanical properties of light weight and high strength.
一些鞘翅虫作为改良前翅,在动态的自然环境中进行变色的同时,对下伏的后翅和柔软的身体进行机械保护,适应性强。鞘膜的变色方式主要有角度依赖型、不可逆型和可逆型三种。本文选用印度罂粟(Popillia indgigonacea Motsch)、李希滕斯坦仙人掌(Sagra femorata purpurea Lichtenstein)和蒂秋香(Dynastes tityus)研究了三种变色风格的颜色形成与轻质高强度力学性能之间的关系。通过角度分辨光谱系统和纳米压头分别获得了紫红色S.f.p.Lichtenstein的光学和纳米力学性能。在有限元分析中,设计了变色相关、无关和整个鞘翅管模型三个几何结构模型,并对每种甲虫的六个耦合仿生模型的力学性能进行了研究。在具有高/小弹性模量和硬度的低/高应力和应变下,表皮中的多层、凸闭合和光子晶体可以通过干涉、散射和光子带隙来完成结构颜色的动态呈现。同时,合理构建了多层和小梁中空的其他微观结构,以协同显示出轻质和高强度的力学性能。
{"title":"The mechanical implementations in three kinds of color-changing beetle elytra","authors":"Wei Wu, Yueming Wang, Jiyu Sun","doi":"10.1680/jbibn.22.00074","DOIUrl":"https://doi.org/10.1680/jbibn.22.00074","url":null,"abstract":"With superior adaptability, some elytron as modified forewing can perform mechanical protection for underlying hindwing and soft body while conduct color-changing in dynamically natural environment. There are mainly three color-changing styles of angle dependence, irreversible and reversible color-changing for elytra. Here, Popillia indgigonacea Motsch, Sagra femorata purpurea Lichtenstein and Dynastes tityus were chosen to investigate the relationship between color formation of three color-changing styles and mechanical properties of light weight and high strength. The optical and nanomechanical properties of purplish red S. f. p. Lichtenstein were obtained through angle-resolved spectroscopy system and nanoindenter, respectively. In finite element analysis, three geometrical structure models of color-changing relevant, irrelevant and the whole elytron models were designed, and then mechanical properties of six coupled bionic models of each beetle were investigated. The multilayer, convex closures and photonic crystal in the epicuticle can complete the dynamic presentation of structural colors by interference, scattering and photonic band gap when resourcefully resist external forces in low/high stress and strain with high/small elastic modulus and hardness. Meanwhile, other microstructures of multilayer and trabecular hollow are reasonably constructed to cooperatively display mechanical properties of light weight and high strength.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42101145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomechanical effect of vibration on the fused lumbar spine with different stabilizers 不同稳定器对融合腰椎振动的生物力学影响
4区 工程技术 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-02-24 DOI: 10.1680/jbibn.21.00020
Wei Fan, Chi Zhang, Dan Zhan, Li-Xin Guo
This study aimed to compare effect of whole-body vibration on biomechanics of fused lumbar spine with different posterior stabilizers, including interspinous process spacer (IPS) and bilateral pedicle screw system (BPSS). Finite element model of lumbar interbody fusion with IPS or BPSS at L4–L5 level was constructed based on a healthy human whole lumbar spine. Transient dynamic and static analyses were employed to compute dynamic responses of deformation and stress for the models to a sinusoidal axial vibration load of ±40 N and its corresponding static axal loads (−40 N and 40 N), respectively. The results showed that for both the IPS and BPSS models, vibration amplitudes of the responses were significantly higher than corresponding changing amplitudes under static loads. The increasing effect of vibration load in endplate stress at L4–L5 reached 128.3% and 146.0% for IPS and BPSS models. By contrast, the increasing effects of vibration load in disc bulge and annulus stress at adjacent L3–L4 were nearly the same for these two models. It indicates that vibration sensitivity of fused level is lower when using IPS compared with BPSS, but there is no obvious difference in vibration sensitivity of adjacent level when using these two stabilizers.
本研究旨在比较全身振动对不同后路稳定器(包括棘突间间隔器(IPS)和双侧椎弓根螺钉系统(BPSS))融合腰椎生物力学的影响。以健康人全腰椎为模型,建立L4-L5椎间融合IPS或BPSS有限元模型。采用瞬态动静态分析方法,分别计算了模型在±40 N正弦轴向振动载荷和相应的静轴向载荷(−40 N和40 N)作用下的动态变形和应力响应。结果表明:无论是IPS模型还是BPSS模型,在静载作用下,响应的振动幅值都明显高于相应的变化幅值;振动载荷对l4 ~ l5端板应力的增加作用在IPS和BPSS模型中分别达到128.3%和146.0%。相比之下,两种模型的振动载荷对圆盘凸起和相邻L3-L4环空应力的增加作用几乎相同。结果表明,与BPSS相比,使用IPS时熔合层的振动灵敏度较低,而使用两种稳定剂时相邻层的振动灵敏度无明显差异。
{"title":"Biomechanical effect of vibration on the fused lumbar spine with different stabilizers","authors":"Wei Fan, Chi Zhang, Dan Zhan, Li-Xin Guo","doi":"10.1680/jbibn.21.00020","DOIUrl":"https://doi.org/10.1680/jbibn.21.00020","url":null,"abstract":"This study aimed to compare effect of whole-body vibration on biomechanics of fused lumbar spine with different posterior stabilizers, including interspinous process spacer (IPS) and bilateral pedicle screw system (BPSS). Finite element model of lumbar interbody fusion with IPS or BPSS at L4–L5 level was constructed based on a healthy human whole lumbar spine. Transient dynamic and static analyses were employed to compute dynamic responses of deformation and stress for the models to a sinusoidal axial vibration load of ±40 N and its corresponding static axal loads (−40 N and 40 N), respectively. The results showed that for both the IPS and BPSS models, vibration amplitudes of the responses were significantly higher than corresponding changing amplitudes under static loads. The increasing effect of vibration load in endplate stress at L4–L5 reached 128.3% and 146.0% for IPS and BPSS models. By contrast, the increasing effects of vibration load in disc bulge and annulus stress at adjacent L3–L4 were nearly the same for these two models. It indicates that vibration sensitivity of fused level is lower when using IPS compared with BPSS, but there is no obvious difference in vibration sensitivity of adjacent level when using these two stabilizers.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45863066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chitosan-coated liposomes of Carrisa spinarum extract: synthesis, analysis and anti-pneumococcal potency 刺五加提取物壳聚糖包被脂质体的合成、分析及抗肺炎球菌效力
4区 工程技术 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-02-16 DOI: 10.1680/jbibn.22.00046
Clarence Rubaka, J. Gathirwa, H. Malebo, H. Swai, N. Sibuyi, A. Hilonga, Admire Dube
In the present study, a chitosan (CS)-coated liposome (LipCsP-Chitosan) nanocarrier was fabricated for the delivery of Carissa spinarum (CsP) polyphenols to improve bioavailability and anti-pneumococcal potential against Klebsiella pneumoniae. LipCsP-Chitosan was synthesized by the ion gelation method and characterized by using a Malvern zetasizer and Fourier Transform Infrared (FTIR); CsP encapsulation and release kinetics were investigated. Anti-pneumococcal activity of the nanoformulations was accessed by agar-well diffusion and microdilution assays. LipCsP-chitosan exhibited a hydrodynamic size and zeta potential of 365.22 ± 0.70 nm and +39.30 ± 0.61 mV, respectively. CsP had an encapsulation efficiency of 81.5%. FTIR analysis revealed the interaction of the liposomes with chitosan and the CsP. A biphasic CsP release profile followed by a sustained release pattern was observed. LiPCsP-Chitosan presented a higher bioaccessibility of polyphenols in the simulated gastric phase (74.1% ± 1.3) than in the simulated intestinal phase (63.32% ± 1.00). LipCsP-chitosan had a relative inhibition zone diameter of 84.33% ± 2.51 when compared to CsP. At minimum inhibition concentration of 31.25 mg/mL, LipCsP-Chitosan reduced the viability of Klebsiella pneumoniae by 57.45% ± 3.76 after 24 h. The results obtained from the current study offer a new approach to the utilization of LipCsP-Chitosan as nanocarriers for candidate anti-pneumococcal agents.
在本研究中,制备了壳聚糖(CS)包被脂质体(lipcsp -壳聚糖)纳米载体,用于递送棘叶多糖(CsP)多酚,以提高其生物利用度和抗肺炎链球菌的潜力。采用离子胶凝法合成了lipcsp -壳聚糖,并利用Malvern zetasizer和傅里叶变换红外(FTIR)对其进行了表征;研究了CsP的包封和释放动力学。通过琼脂孔扩散和微稀释试验获得纳米制剂的抗肺炎球菌活性。lipcsp -壳聚糖的水动力尺寸为365.22±0.70 nm, zeta电位为+39.30±0.61 mV。CsP包封率为81.5%。FTIR分析显示脂质体与壳聚糖和CsP的相互作用。观察到两相CsP释放概况,随后是持续释放模式。lipcsp -壳聚糖在模拟胃期对多酚的生物可及性(74.1%±1.3)高于模拟肠期(63.32%±1.00)。与CsP相比,lipcsp -壳聚糖的相对抑制带直径为84.33%±2.51。在最低抑制浓度为31.25 mg/mL时,24 h后,lipcsp -壳聚糖对肺炎克雷伯菌的抑制率为57.45%±3.76。本研究的结果为利用lipcsp -壳聚糖作为候选抗肺炎球菌药物的纳米载体提供了新的途径。
{"title":"Chitosan-coated liposomes of Carrisa spinarum extract: synthesis, analysis and anti-pneumococcal potency","authors":"Clarence Rubaka, J. Gathirwa, H. Malebo, H. Swai, N. Sibuyi, A. Hilonga, Admire Dube","doi":"10.1680/jbibn.22.00046","DOIUrl":"https://doi.org/10.1680/jbibn.22.00046","url":null,"abstract":"In the present study, a chitosan (CS)-coated liposome (LipCsP-Chitosan) nanocarrier was fabricated for the delivery of Carissa spinarum (CsP) polyphenols to improve bioavailability and anti-pneumococcal potential against Klebsiella pneumoniae. LipCsP-Chitosan was synthesized by the ion gelation method and characterized by using a Malvern zetasizer and Fourier Transform Infrared (FTIR); CsP encapsulation and release kinetics were investigated. Anti-pneumococcal activity of the nanoformulations was accessed by agar-well diffusion and microdilution assays. LipCsP-chitosan exhibited a hydrodynamic size and zeta potential of 365.22 ± 0.70 nm and +39.30 ± 0.61 mV, respectively. CsP had an encapsulation efficiency of 81.5%. FTIR analysis revealed the interaction of the liposomes with chitosan and the CsP. A biphasic CsP release profile followed by a sustained release pattern was observed. LiPCsP-Chitosan presented a higher bioaccessibility of polyphenols in the simulated gastric phase (74.1% ± 1.3) than in the simulated intestinal phase (63.32% ± 1.00). LipCsP-chitosan had a relative inhibition zone diameter of 84.33% ± 2.51 when compared to CsP. At minimum inhibition concentration of 31.25 mg/mL, LipCsP-Chitosan reduced the viability of Klebsiella pneumoniae by 57.45% ± 3.76 after 24 h. The results obtained from the current study offer a new approach to the utilization of LipCsP-Chitosan as nanocarriers for candidate anti-pneumococcal agents.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46007615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomimetic cryogels based on carboxymethyl chitosan/gelatin/hydroxyapatite for bone tissue engineering 基于羧甲基壳聚糖/明胶/羟基磷灰石的骨组织工程仿生冷冻材料
4区 工程技术 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-02-08 DOI: 10.1680/jbibn.22.00020
Bahar Asadi, H. Mirzadeh, N. Olov, Ali Samadikuchaksaraei, Raheleh Kheirbakhsh, R. Moradi, S. Amanpour, S. Bagheri‐Khoulenjani
Gelation at temperature below freezing point of solvent is known as cryogelation that attracted attention in regenerative medicine due to improved mechanical and structural properties. This study focuses on using cryogelation as a versatile method for fabricating biomimetic scaffolds with improved mechanical strength and larger pore size with potential for bone tissue engineering applications. These scaffolds comprising carboxymethyl-chitosan/gelatin/ nano-hydroxyapatite were formed via cryogelation. The effects of three parameters, including crosslinker concentration, mineral content and gelatin-to-polymer ratio, were investigated on the physical, chemical and mechanical properties. In this work, MG63 cells were used for in vitro assay. In addition, in vivo assay was conducted to investigate the biocompatibility of nanocomposite scaffolds. The results showed that all scaffolds have a porous structure with interconnected pores with morphology similar to bone structure. Their pore size, porosity, and swelling ratio decreased with increased crosslinker concentration, while nano-hydroxyapatite has the opposite effect. XRD results also showed that the inorganic phase retained its crystallinity in the substrate with a slight decrease in crystal size. In addition, the scaffold showed no toxicity in either in vitro or in vivo studies. Obtained results showed that the biomimetic cryogels based on carboxymerthyl chitosan/gelatin/hydroxyapatite has a potential for bone tissue engineering.
在低于溶剂冰点的温度下进行的凝胶化被称为冷冻凝胶化,由于其机械和结构性能的改善,在再生医学中引起了关注。本研究的重点是使用冷冻凝胶作为一种通用的方法来制备仿生支架,该支架具有提高的机械强度和更大的孔径,具有骨组织工程应用的潜力。这些包含羧甲基壳聚糖/明胶/纳米羟基磷灰石的支架是通过冷冻凝胶形成的。研究了交联剂浓度、矿物含量和明胶与聚合物的比例三个参数对其物理、化学和力学性能的影响。在这项工作中,MG63细胞被用于体外测定。此外,还进行了体内实验来研究纳米复合支架的生物相容性。结果表明,所有支架都具有多孔结构,孔隙相互连接,形态与骨结构相似。它们的孔径、孔隙率和溶胀率随着交联剂浓度的增加而降低,而纳米羟基磷灰石则具有相反的作用。XRD结果还表明,无机相在基体中保持了结晶度,晶体尺寸略有减小。此外,该支架在体外或体内研究中均未显示毒性。结果表明,基于羧甲基壳聚糖/明胶/羟基磷灰石的仿生冷冻凝胶具有骨组织工程的潜力。
{"title":"Biomimetic cryogels based on carboxymethyl chitosan/gelatin/hydroxyapatite for bone tissue engineering","authors":"Bahar Asadi, H. Mirzadeh, N. Olov, Ali Samadikuchaksaraei, Raheleh Kheirbakhsh, R. Moradi, S. Amanpour, S. Bagheri‐Khoulenjani","doi":"10.1680/jbibn.22.00020","DOIUrl":"https://doi.org/10.1680/jbibn.22.00020","url":null,"abstract":"Gelation at temperature below freezing point of solvent is known as cryogelation that attracted attention in regenerative medicine due to improved mechanical and structural properties. This study focuses on using cryogelation as a versatile method for fabricating biomimetic scaffolds with improved mechanical strength and larger pore size with potential for bone tissue engineering applications. These scaffolds comprising carboxymethyl-chitosan/gelatin/ nano-hydroxyapatite were formed via cryogelation. The effects of three parameters, including crosslinker concentration, mineral content and gelatin-to-polymer ratio, were investigated on the physical, chemical and mechanical properties. In this work, MG63 cells were used for in vitro assay. In addition, in vivo assay was conducted to investigate the biocompatibility of nanocomposite scaffolds. The results showed that all scaffolds have a porous structure with interconnected pores with morphology similar to bone structure. Their pore size, porosity, and swelling ratio decreased with increased crosslinker concentration, while nano-hydroxyapatite has the opposite effect. XRD results also showed that the inorganic phase retained its crystallinity in the substrate with a slight decrease in crystal size. In addition, the scaffold showed no toxicity in either in vitro or in vivo studies. Obtained results showed that the biomimetic cryogels based on carboxymerthyl chitosan/gelatin/hydroxyapatite has a potential for bone tissue engineering.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45117758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biogenic material formation by the treatment of stone waste with biologically induced mineralization 生物诱导矿化处理石屑形成生物材料
4区 工程技术 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-02-02 DOI: 10.1680/jbibn.21.00007
Erdem Gunsur, Hande Mumcu, C. Demir, Nevin Gul Karaguler, M. Karagüler
One of the most widely studied branches of biologically induced mineralization (BIM) processes is called microbially induced calcium carbonate precipitation (MICCP) also known as microbially induced calcite precipitation (MICP) can be used as a method for the reinterpretation of waste natural stone particles into a sustainable material. By overcoming the need for synthetic adhesives or energy consuming firing or sintering procedures for regaining such wastes, a natural and sustainable solution is proposed through certain biological treatment processes. The aim of this study was to determine main processing variables affecting the microbially induced biocement production using waste stone as a scaffold material. Bacillus pasteurii bacteria are used for biological induction of calcite precipitation. A custom-made reactor was designed for controlled incubation and media injection to the waste stone scaffold. Parameters examined were particle size of the waste stones, effect of stone type on cementation, urease activity of the bacterial culture, temperature, pH and flow rate of media, mechanical strength of cemented scaffolds and water absorption capacity. This research demonstrates a potential solution towards the waste generation problem of the global natural stone industry through the treatment of such wastes with biologically induced mineralization for creating a sustainable and biogenic material.
生物诱导矿化(BIM)过程中研究最广泛的分支之一被称为微生物诱导碳酸钙沉淀(MICCP),也称为微生物诱导方解石沉淀(MICP),可作为将废弃天然石颗粒重新解释为可持续材料的方法。通过克服对合成粘合剂的需求,或通过消耗能源的烧制或烧结程序来回收此类废物,通过某些生物处理工艺提出了一种自然和可持续的解决方案。本研究的目的是确定影响使用废弃石头作为支架材料的微生物诱导生物水泥生产的主要工艺变量。巴氏杆菌用于方解石沉淀的生物诱导。设计了一个定制的反应器,用于受控培养和介质注入废石支架。检测的参数包括废石块的粒径、石块类型对胶结的影响、细菌培养物的脲酶活性、培养基的温度、pH和流速、胶结支架的机械强度和吸水能力。这项研究表明,通过生物诱导矿化处理此类废物,创造可持续的生物材料,可以解决全球天然石材行业的废物产生问题。
{"title":"Biogenic material formation by the treatment of stone waste with biologically induced mineralization","authors":"Erdem Gunsur, Hande Mumcu, C. Demir, Nevin Gul Karaguler, M. Karagüler","doi":"10.1680/jbibn.21.00007","DOIUrl":"https://doi.org/10.1680/jbibn.21.00007","url":null,"abstract":"One of the most widely studied branches of biologically induced mineralization (BIM) processes is called microbially induced calcium carbonate precipitation (MICCP) also known as microbially induced calcite precipitation (MICP) can be used as a method for the reinterpretation of waste natural stone particles into a sustainable material. By overcoming the need for synthetic adhesives or energy consuming firing or sintering procedures for regaining such wastes, a natural and sustainable solution is proposed through certain biological treatment processes. The aim of this study was to determine main processing variables affecting the microbially induced biocement production using waste stone as a scaffold material. Bacillus pasteurii bacteria are used for biological induction of calcite precipitation. A custom-made reactor was designed for controlled incubation and media injection to the waste stone scaffold. Parameters examined were particle size of the waste stones, effect of stone type on cementation, urease activity of the bacterial culture, temperature, pH and flow rate of media, mechanical strength of cemented scaffolds and water absorption capacity. This research demonstrates a potential solution towards the waste generation problem of the global natural stone industry through the treatment of such wastes with biologically induced mineralization for creating a sustainable and biogenic material.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47233348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Bioinspired Biomimetic and Nanobiomaterials
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1