Developmental Cognitive Neuroscience最新文献_第10页

The role of peer relationship on children's creativity during cooperative and competitive interactions: An fNIRS-based hyperscanning study 合作与竞争互动中同伴关系对儿童创造力的影响：基于fnir的超扫描研究

IF 4.6 2区医学 Q1 NEUROSCIENCES

Developmental Cognitive Neuroscience

Pub Date : 2025-07-03 DOI: 10.1016/j.dcn.2025.101592

Shujin Zhou , Yuxuan Zhang , Mingming Zhang , Dan Li

Children are at a critical stage of development for cultivating creativity and are highly sensitive to the influence of peers. This study investigated the impact of peer relationships on children's creativity during both cooperative and competitive interactions, using functional near-infrared spectroscopy (fNIRS)-based hyperscanning techniques. A total of 66 children, including 18 familiar dyads and 15 stranger dyads, were recruited to participate in the cooperative and competitive tangram puzzle tasks. The results showed that familiar dyads demonstrated higher originality and lower appropriateness in cooperative tasks compared to stranger dyads. fNIRS data revealed distinct task-specific neural coupling patterns in the inferior frontal gyrus (IFG) contingent upon peer relationship: familiar dyads exhibited enhanced inter-brain synchronization (IBS) during cooperative tasks, while stranger dyads demonstrated stronger neural alignment during competitive interactions. Additionally, positive feedback during cooperative interactions in familiar dyads was significantly correlated with increased IBS in the IFG. These findings underscore the advantages of familiar peer relationships in fostering cooperative creativity and the benefits of strange relationships in enhancing competitive performance. This study highlights the importance of considering relational and contextual factors in fostering children’s creative potential.

儿童正处于培养创造力的关键发展阶段，对同龄人的影响非常敏感。本研究利用基于功能近红外光谱（fNIRS）的超扫描技术，研究了同伴关系对儿童在合作和竞争互动中创造力的影响。共招募了66名儿童，其中包括18名熟悉的双人组和15名陌生的双人组，参与合作和竞争的七巧板拼图任务。结果表明，熟悉的二人组在合作任务中表现出更高的独创性和更低的适当性。fNIRS数据揭示了同伴关系下额下回（IFG）中不同的任务特异性神经耦合模式：熟悉的二对在合作任务中表现出增强的脑间同步（IBS），而陌生的二对在竞争互动中表现出更强的神经校准。此外，在熟悉的二人组中，合作互动中的正反馈与IFG中IBS的增加显著相关。这些发现强调了熟悉的同伴关系在培养合作创造力方面的优势，以及陌生关系在提高竞争绩效方面的好处。本研究强调了在培养儿童创造潜能时考虑关系因素和情境因素的重要性。

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引用次数: 0

Sex differences in the neural correlates of affective reactivity and regulation in early adolescence 青春期早期情感反应和调节的神经相关的性别差异

IF 4.6 2区医学 Q1 NEUROSCIENCES

Developmental Cognitive Neuroscience

Pub Date : 2025-06-26 DOI: 10.1016/j.dcn.2025.101588

Leah D. Church , Nadia Bounoua , Kavya Bhattiprolu , Julia Merker , Jeffrey M. Spielberg

Internalizing disorders are the leading cause of disability worldwide. Despite this public health crisis, borne disproportionately by female adolescents, specific neural mechanisms driving these differences remain unclear. The present study investigated sex differences in the neural circuitry underlying emotion regulation in a community sample of 180 early adolescents (M_age= 12.03 years; 54.4 % female). Participants were instructed to either react naturally or regulate their affective responses to negative or neutral stimuli. Voxelwise analyses revealed a significant 3-way interaction between sex, regulation (e.g., regulate vs. react), and stimulus valence (e.g., negative vs. neutral) in bilateral middle/medial orbitofrontal cortex (OFC), right middle frontal gyrus (MFG), and right amygdala. Specifically, female adolescents recruited bilateral OFC when asked to regulate their responses to aversive images. Recruitment of left (but not right) OFC was greater for male adolescents than female adolescents when regulating their responses to neutral stimuli. Finally, greater deactivation of right MFG was found when female adolescents reacted naturally to aversive stimuli, relative to male adolescents. These regions play critical roles in cognitive processes involved in emotion regulation. Our identification of sex-specific mechanisms supporting affective processes in early adolescents may reflect risk factors that can be intervened upon before the crystallization of internalizing pathology.

内化障碍是全世界致残的主要原因。尽管这种公共卫生危机主要由女性青少年承担，但导致这些差异的具体神经机制仍不清楚。本研究调查了180名社区早期青少年(年龄= 12.03岁；54.4 %女)。参与者被要求对消极或中性刺激做出自然反应或调节自己的情感反应。体素分析显示，在双侧中/内侧眶额皮质（OFC）、右侧额叶中回（MFG）和右侧杏仁核中，性别、调节（如调节vs.反应）和刺激效价（如负性vs.中性）之间存在显著的3向相互作用。具体来说，当被要求调节她们对厌恶图像的反应时，女性青少年使用了双侧OFC。在调节对中性刺激的反应时，男性青少年的左侧OFC比女性青少年的左侧OFC募集更多（而不是右侧OFC）。最后，与男性青少年相比，当女性青少年对厌恶刺激做出自然反应时，右侧MFG的失活程度更高。这些区域在涉及情绪调节的认知过程中起着关键作用。我们对支持青少年早期情感过程的性别特异性机制的识别可能反映了可以在内化病理结晶之前进行干预的风险因素。

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引用次数: 0

A Bayesian Regularized and Annotation-Informed Integrative Analysis of Cognition (BRAINIAC) 基于贝叶斯正则化和标注的认知综合分析（BRAINIAC）

IF 4.6 2区医学 Q1 NEUROSCIENCES

Developmental Cognitive Neuroscience

Pub Date : 2025-06-25 DOI: 10.1016/j.dcn.2025.101569

Rong W. Zablocki , Bohan Xu , Chun-Chieh Fan , Wesley K. Thompson

We present the novel Bayesian Regularized and Annotation-Informed Integrative Analysis of Cognition (BRAINIAC) model. BRAINIAC allows for estimation of total variance explained by all features for a given cognitive phenotype, as well as a principled assessment of the impact of annotations on relative enrichment of predictive features compared to others in terms of variance explained, without relying on a potentially unrealistic assumption of sparsity of brain–behavior associations. We validate BRAINIAC in Monte Carlo simulation studies. In real data analyses, we train the BRAINIAC model on resting state functional magnetic resonance imaging (rsMRI) and neuropsychiatric data from the Adolescent Brain Cognitive Development (ABCD) Study and use the trained model in an out-of-study application to harmonized resting-state data from the Human Connectome Project Development (HCP-D), demonstrating a substantial improvement in out-of-study predictive power by incorporating relevant annotations into the BRAINIAC model.

我们提出了一种新的贝叶斯正则化和标注信息的认知综合分析（BRAINIAC）模型。BRAINIAC允许对给定认知表型的所有特征解释的总方差进行估计，以及对注释对预测特征相对丰富程度的影响进行原则评估，而不依赖于对大脑行为关联的稀疏性的潜在不切实际的假设。我们在蒙特卡洛模拟研究中验证了BRAINIAC。在实际数据分析中，我们对BRAINIAC模型进行了静息状态功能磁共振成像（rsMRI）和来自青少年大脑认知发展（ABCD）研究的神经精神病学数据的训练，并将训练后的模型用于一个非学习应用中，以协调来自人类连接组项目发展（HCP-D）的静息状态数据，通过将相关注释纳入BRAINIAC模型，证明了在非学习状态下预测能力的显著提高。

引用次数: 0

Cognitive interference elicits developmental sex differences in inhibitory control 认知干扰引起抑制控制的发育性别差异

IF 4.6 2区医学 Q1 NEUROSCIENCES

Developmental Cognitive Neuroscience

Pub Date : 2025-06-25 DOI: 10.1016/j.dcn.2025.101590

Jake J. Son , Abraham D. Killanin , Mikki Schantell , Yasra Arif , Thomas W. Ward , Maggie P. Rempe , Grace C. Ende , Hannah J. Okelberry , Danielle L. Rice , Anna T. Coutant , Julia M. Stephen , Yu-Ping Wang , Vince D. Calhoun , Alex I. Wiesman , Tony W. Wilson

Inhibitory control is a key component of cognitive control that enables children and adolescents to develop increasingly complex skills throughout development. These processes are subject to insult via endogenous and environmental stressors (e.g., puberty, trauma) and alterations can lead to significant behavioral impairments that persist into adulthood. Despite this, the normative developmental course of neural oscillatory activity underlying interference control, a critical subcomponent of inhibitory control, and potential sex differences along this course, remain poorly understood. Herein, we utilized high-density magnetoencephalography (MEG) during the Eriksen flanker task to map the developmental sensitivity of neural processes supporting interference control in a large sample of children and adolescents (N = 121). MEG data were transformed into the time-frequency domain and significant oscillatory responses were imaged using a beamformer. Whole-brain analysis of flanker interference maps (i.e., incongruent - congruent trials) revealed age-related decreases in theta power in the supplementary motor area and cerebellum. Furthermore, regions known to be critical for supporting cognitive control, including the prefrontal and parietal cortices, exhibited age-by-sex interactive effects, suggesting modulation of interference control throughout development in a sex-dependent manner. Taken together, these data contribute to the characterization of the electrophysiological mechanisms supporting the development and refinement of interference control.

抑制性控制是认知控制的一个关键组成部分，它使儿童和青少年在整个发展过程中发展出越来越复杂的技能。这些过程会受到内源性和环境压力因素（例如，青春期、创伤）的影响，而这些改变会导致持续到成年的重大行为障碍。尽管如此，作为抑制控制的一个重要组成部分，干扰控制下的神经振荡活动的规范发育过程，以及这一过程中潜在的性别差异，仍然知之甚少。在此，我们在埃里克森侧侧任务中使用高密度脑磁图（MEG）来绘制支持干扰控制的神经过程在儿童和青少年中的发育敏感性（N = 121）。MEG数据被转换成时频域，并使用波束形成器对显著的振荡响应进行成像。侧侧干扰图的全脑分析（即，不一致-一致试验）显示辅助运动区和小脑的θ波功率与年龄相关。此外，已知对支持认知控制至关重要的区域，包括前额叶和顶叶皮层，显示出年龄与性别的相互作用，表明在整个发育过程中，干扰控制以性别依赖的方式进行调节。综上所述，这些数据有助于表征支持干扰控制发展和完善的电生理机制。

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引用次数: 0

Cognition is associated with task-related brain network reconfiguration in late childhood 认知与儿童后期任务相关的大脑网络重构有关

IF 4.6 2区医学 Q1 NEUROSCIENCES

Developmental Cognitive Neuroscience

Pub Date : 2025-06-24 DOI: 10.1016/j.dcn.2025.101589

Mackenzie E. Mitchell , Ashley J. Jaimes , Tehila Nugiel

In order to transition between a resting state and carrying out cognitively-demanding processes the brain makes a host of subtle changes to its network organization. In adults, less reconfiguration relates to better task performance, suggesting a preconfigured brain organization at rest is beneficial, such that only minute changes are required to execute task demands. Here, we take a developmental lens to this phenomenon, examining reconfiguration in late childhood by leveraging a large sample of 9–11 year olds from the Adolescent Brain and Cognitive Development Study. We find more reconfiguration between the resting state and two executive function tasks is related to better task performance. These relationships hold even when accounting for network segregation, though segregation was negatively related to reconfiguration. Reconfiguration was also related to crystallized intelligence, with diverging effects across tasks. Overall, these findings demonstrate that in contrast to adulthood during late childhood, before functional brain networks are fully mature, greater reconfiguration promotes successful task performance.

为了在休息状态和执行认知要求的过程之间转换，大脑对其网络组织进行了一系列微妙的改变。在成年人中，较少的重新配置与更好的任务表现有关，这表明在休息时预先配置的大脑组织是有益的，这样只需要微小的改变就可以执行任务需求。在这里，我们从发展的角度来看待这一现象，通过利用青少年大脑和认知发展研究中9-11岁儿童的大量样本来检查儿童后期的重新配置。我们发现静息状态和两个执行功能任务之间的重构越多，任务表现越好。即使考虑到网络隔离，这些关系仍然成立，尽管隔离与重新配置负相关。重构也与结晶智力有关，在不同的任务中有不同的影响。总的来说，这些发现表明，与儿童期后期的成年期相比，在大脑功能网络完全成熟之前，更大的重构促进了成功的任务表现。

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引用次数: 0

Associations among socioeconomic disadvantage, longitudinal changes in within-network connectivity, and academic outcomes in the ABCD study ABCD研究中社会经济劣势、网络内连通性的纵向变化和学术成果之间的关系

IF 4.6 2区医学 Q1 NEUROSCIENCES

Developmental Cognitive Neuroscience

Pub Date : 2025-06-23 DOI: 10.1016/j.dcn.2025.101587

Divyangana Rakesh , Ekaterina Sadikova , Katie A. McLaughlin

Lower parental socioeconomic status (SES) is consistently linked to lower academic achievement among adolescents, with early disparities persisting into adulthood. However, the neurobiological mechanisms underlying these associations are not well understood. This preregistered study investigates the associations between household and neighborhood disadvantage—measured by income-to-needs ratio, parental educational attainment, and neighborhood SES—changes in within-network functional connectivity, and school grades, using longitudinal data from the Adolescent Brain Cognitive Development Study (N = 4745; age at baseline = 119.1 ± 7.5 months; age at 2-year follow up = 143.6 ± 7.8 months; age at 3-year follow up = 154.8 ± 7.7 months). Within-network connectivity changed significantly from baseline to follow-up, increasing in most networks (e.g., default mode, fronto-parietal) and decreasing in a few (e.g., salience, ventral attention). After controlling for other SES indicators, parental education and neighborhood disadvantage, but not income, were associated with changes in connectivity across several brain networks, including reduced increases in default mode, cingulo-opercular, and visual network connectivity and greater increases in within-sensorimotor network connectivity. Further, changes in sensorimotor connectivity mediated the relationship between parental educational attainment and academic achievement three years later. These findings highlight the importance of parental education and neighborhood environments in shaping neurodevelopmental trajectories that influence academic outcomes. Understanding the mechanisms that link socioeconomic disadvantage with academic outcomes could inform interventions aimed at reducing persistent achievement gaps.

父母较低的社会经济地位（SES）一直与青少年较低的学习成绩有关，这种早期差异一直持续到成年。然而，这些关联背后的神经生物学机制尚不清楚。本预登记研究利用青少年大脑认知发展研究（N = 4745;N = 4745）的纵向数据，调查了家庭和社区劣势之间的联系——通过收入与需求比、父母受教育程度和社区ses来衡量——网络内部功能连通性的变化和学校成绩。基线年龄= 119.1 ± 7.5个月；2年随访时年龄= 143.6 ± 7.8个月；3年随访年龄= 154.8 ± 7.7个月)。从基线到随访，网络内连通性发生了显著变化，大多数网络（例如，默认模式，额顶叶）增加，少数网络（例如，突出性，腹侧注意）减少。在控制了其他社会经济地位指标后，父母的教育程度和邻居的不利条件，而不是收入，与几个大脑网络的连通性变化有关，包括默认模式、扣环-眼和视觉网络连通性的增加减少，以及内部感觉运动网络连通性的增加增加。此外，三年后，感觉运动连通性的变化介导了父母受教育程度与学业成绩之间的关系。这些发现强调了父母教育和社区环境在塑造影响学业成绩的神经发育轨迹方面的重要性。了解社会经济劣势与学业成绩之间的联系机制，可以为旨在减少持续成绩差距的干预措施提供信息。

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引用次数: 0

Causal effects of physical activity and screen time on childhood intelligence via Mendelian randomization: The mediating role of intracranial volume 通过孟德尔随机化，体育活动和屏幕时间对儿童智力的因果影响：颅内容积的中介作用

IF 4.6 2区医学 Q1 NEUROSCIENCES

Developmental Cognitive Neuroscience

Pub Date : 2025-06-20 DOI: 10.1016/j.dcn.2025.101586

Junjiao Feng , Yi Wan , Liang Zhang

Growing evidence suggests that physical activity and screen time affect intelligence (IQ) during childhood, a critical period for brain development, yet the relationship between these factors remains controversial. Using bidirectional Mendelian randomization (MR), we investigated these associations while accounting for potential reverse causality. Our two-sample MR analysis revealed a positive causal effect of moderate to vigorous physical activity (PA) on childhood IQ (β = 0.42, 95 % confidence interval (CI): [0.12, 0.72], p = 6.26 × 10⁻³), whereas leisure screen time (LST) exhibited a negative causal effect (β = −0.35, 95 % CI: [ −0.60, −0.10], p = 5.59 ×10⁻³). Reverse MR analysis found no evidence of causations. A two-step MR mediation framework further suggested that the intracranial volume (ICV) mediated 21.69 % (95 % CI: [15.25 %, 28.13 %]) of the negative effect of LST on childhood IQ. These MR-derived findings demonstrate that PA positively influences childhood IQ, whereas LST negatively impacts it, partly through reduced ICV. By leveraging genetic instruments, this study strengthens causal inference and highlights the potential of PA promotion and screen time reduction to support cognitive development. Further research is needed to elucidate the mechanisms underlying these associations and their long-term cognitive consequences.

越来越多的证据表明，体育活动和屏幕时间会影响儿童时期的智力（IQ），而儿童时期是大脑发育的关键时期，但这些因素之间的关系仍然存在争议。使用双向孟德尔随机化（MR），我们调查了这些关联，同时考虑了潜在的反向因果关系。我们两个示例,分析显示中度到剧烈的身体活动的积极的因果效应(PA)对儿童智商(β= 0.42,95 %可信区间(CI): [0.12, 0.72], p = 6.26  × 10−3),而休闲屏幕时间(LST)表现出负因果效应(β=−0.35,95 % CI:[−0.60−0.10],p = 5.59  ×10−3)。反向核磁共振分析没有发现因果关系的证据。两步磁共振中介框架进一步表明，颅内容积（ICV）介导了21.69 %（95 % CI:[15.25 %,28.13 %]）的LST对儿童智商的负影响。这些mr衍生的研究结果表明，PA对儿童智商有积极影响，而LST对儿童智商有消极影响，部分原因是ICV的降低。通过利用遗传工具，本研究加强了因果推理，并强调了PA促进和屏幕时间减少支持认知发展的潜力。需要进一步的研究来阐明这些关联的机制及其长期认知后果。

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引用次数: 0

Fetal functional connectivity: Examining the role of prenatal maternal depression symptoms using graph theory 胎儿功能连通性：使用图论检查产前母亲抑郁症状的作用

IF 4.6 2区医学 Q1 NEUROSCIENCES

Developmental Cognitive Neuroscience

Pub Date : 2025-06-16 DOI: 10.1016/j.dcn.2025.101585

Ellyn Reed , Lanxin Ji , Marjorie Beeghly , Amyn Majbri , Tanya Bhatia , Mark Duffy , Iris Menu , Christopher Trentacosta , Moriah E. Thomason

Altered fetal brain function is proposed as a mechanism underlying the relationship between prenatal maternal depression (PMD) and neurodevelopmental outcomes in offspring. This study investigated the association between PMD symptoms and fetal brain functional connectivity (FC) using graph theory. A total of 123 pregnant women participated in the study, completed the Center for Epidemiologic Studies Depression Scale (CES-D), and underwent fetal MRI scans. Results revealed a significant relationship between elevated PMD symptoms and reduced global efficiency in the right insular region of the fetal brain. However, because fetal age was not associated with local or global efficiency in the insular brain region, we cannot determine if the PMD-related reduction in insula global efficiency is indicative of an accelerated or delayed developmental pattern. This study is one of the few to examine fetal brain connectivity in relation to prenatal maternal depression, providing valuable insights into early neurodevelopmental risks and potential targets for early intervention.

胎儿脑功能改变被认为是产前母亲抑郁（PMD）与后代神经发育结果之间关系的潜在机制。本研究运用图论探讨经前抑郁症状与胎儿脑功能连接（FC）的关系。共有123名孕妇参与了这项研究，完成了流行病学研究中心抑郁量表（CES-D），并接受了胎儿核磁共振扫描。结果显示，PMD症状升高与胎儿大脑右岛区整体效率降低之间存在显著关系。然而，由于胎儿年龄与岛脑区域的局部或整体效率无关，我们无法确定pmd相关的岛脑整体效率降低是否表明发育模式加速或延迟。这项研究是为数不多的研究胎儿大脑连接与产前母亲抑郁症相关的研究之一，为早期神经发育风险和早期干预的潜在目标提供了有价值的见解。

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引用次数: 0

Multimodal analysis of neural signals related to source memory encoding in young children 幼儿源记忆编码相关神经信号的多模态分析

IF 4.6 2区医学 Q1 NEUROSCIENCES

Developmental Cognitive Neuroscience

Pub Date : 2025-06-13 DOI: 10.1016/j.dcn.2025.101580

Yuqing Lei , John Richards , Fengji Geng , Tracy Riggins

The emergence of source memory is an important milestone during memory development. Decades of research has explored neural correlates of source memory using electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). However, connections between findings from the two approaches, particularly within children, remain unclear. This study identified fMRI-informed cortical sources of two EEG signals during memory encoding, the P2 and the late slow wave (LSW), that predicted subsequent source memory performance in a sample of children aged 4 to 8 years. Both P2 and LSW were source localized to cortical areas of the medial temporal lobe (MTL), reflecting MTL’s crucial role in both early-stage information processing and late-stage integration of memory, and validating LSW’s suspected role in memory updating. The P2 effect was localized to all six tested subregions of cortical MTL in both left and right hemispheres, whereas the LSW effect was only localized to the parahippocampal cortex and entorhinal cortex. P2 was additionally localized to multiple areas in the frontoparietal network, suggesting interactions between memory encoding and other cognitive functions. These results reflect the importance and potential of considering both spatial and temporal aspects of neural activity to decode memory mechanisms, paving the way for future developmental research.

源记忆的出现是记忆发展的一个重要里程碑。几十年的研究利用脑电图（EEG）和功能磁共振成像（fMRI）探索了源记忆的神经相关性。然而，两种方法的发现之间的联系，特别是在儿童中，仍然不清楚。本研究确定了在记忆编码过程中两个脑电信号的fmri皮质源，P2和晚慢波（LSW），预测了4至8岁儿童的后续源记忆表现。P2和LSW均来源于内侧颞叶皮质区，反映了内侧颞叶在早期信息加工和后期记忆整合中的重要作用，验证了内侧颞叶在记忆更新中的作用。P2效应定位于左、右半球皮层MTL的所有6个测试亚区，而LSW效应仅定位于海马旁皮层和内嗅皮层。此外，P2位于额顶叶网络的多个区域，表明记忆编码与其他认知功能之间存在相互作用。这些结果反映了考虑神经活动的空间和时间方面来解码记忆机制的重要性和潜力，为未来的发展研究铺平了道路。

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引用次数: 0

Self-referential encoding in the developing brain 发育中的大脑中的自我参照编码

IF 4.6 2区医学 Q1 NEUROSCIENCES

Developmental Cognitive Neuroscience

Pub Date : 2025-06-06 DOI: 10.1016/j.dcn.2025.101581

Hilary Sweatman , Ying He , Ross Lawrence , Xiaoqian J. Chai

Episodic memory is closely linked to the self and information related to the self tends to be better remembered. In adults, the brain’s default mode network (DMN) supports self-referential thought and memory, with the medial prefrontal cortex (mPFC) being important for both functions. How the DMN supports self-referential encoding in children, and where in the mPFC the processes of self-referencing and episodic memory interact, is unknown. We investigated the neural development of self-referential encoding in 83 participants ages 7—25. While undergoing MRI, participants viewed objects and answered self-referential or semantic questions. Self-referential compared to semantic encoding resulted in better recollection across all ages. Self-referential encoding was associated with greater activation across the DMN and inferior frontal gyrus (IFG), with age-related increases in the dorsal mPFC and left IFG. Region-of-interest analyses revealed the interaction of self-referential episodic memory in the anterior mPFC and left hippocampus. The dorsal and anterior mPFC showed a counteraction effect of self-related thinking with the previously demonstrated age-related increase in DMN deactivation for subsequent memory encoding. These results suggest that self-referential facilitation matures and interacts with the episodic memory system in the brain to support the development of episodic memory from childhood to adulthood.

情景记忆与自我密切相关，与自我相关的信息往往更容易被记住。在成年人中，大脑的默认模式网络（DMN）支持自我参照思维和记忆，内侧前额叶皮层（mPFC）对这两种功能都很重要。DMN如何支持儿童的自我参照编码，以及在mPFC中自我参照和情景记忆的过程在哪里相互作用，这些都是未知的。研究了83名年龄在7 ~ 25岁的被试的自我参照编码的神经发育情况。在接受核磁共振成像时，参与者观看物体并回答自我指涉或语义问题。与语义编码相比，自我参照在所有年龄段都能产生更好的记忆。自我参照编码与DMN和额下回（IFG）更大的激活有关，与背侧mPFC和左侧IFG的年龄相关的增加有关。兴趣区分析揭示了自我参照情景记忆在前皮层和左海马区的相互作用。背侧和前部的mPFC显示出自我相关思维与先前证明的年龄相关的DMN失活增加的反作用，从而导致随后的记忆编码。这些结果表明，自我指涉促进的成熟并与大脑情景记忆系统相互作用，支持情景记忆从童年到成年的发展。

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引用次数: 0