Pub Date : 2025-12-20DOI: 10.1016/j.shpsa.2025.102098
Adrian Erasmus
Disease classification plays an important role in numerous medical goals, from improving communication between researchers, physicians, and insurers to diagnosis and therapeutic prediction. Therefore, it's important to understand the principles behind our classificatory practices with a view to adopting the approach to disease classification that best serves the practical interests of medical science. In this paper, I discuss three prominent approaches to disease classification: the etiological approach, symptom-based approach, and pathophysiological approach, highlighting strengths and weaknesses of each. My main goal is to defend a pragmatic goal-directed approach to disease classification. I argue that choices about which classificatory approach to use should principally depend on the medical goal being pursued. Drawing from existing pragmatic accounts of classification in science, I suggest that the goal in question determines what kind of information about a disease is important and this, in turn, determines which classificatory approach to apply in service of that goal.
{"title":"A goal-directed approach to disease classification","authors":"Adrian Erasmus","doi":"10.1016/j.shpsa.2025.102098","DOIUrl":"10.1016/j.shpsa.2025.102098","url":null,"abstract":"<div><div>Disease classification plays an important role in numerous medical goals, from improving communication between researchers, physicians, and insurers to diagnosis and therapeutic prediction. Therefore, it's important to understand the principles behind our classificatory practices with a view to adopting the approach to disease classification that best serves the practical interests of medical science. In this paper, I discuss three prominent approaches to disease classification: the etiological approach, symptom-based approach, and pathophysiological approach, highlighting strengths and weaknesses of each. My main goal is to defend a pragmatic goal-directed approach to disease classification. I argue that choices about which classificatory approach to use should principally depend on the medical goal being pursued. Drawing from existing pragmatic accounts of classification in science, I suggest that the goal in question determines what kind of information about a disease is important and this, in turn, determines which classificatory approach to apply in service of that goal.</div></div>","PeriodicalId":49467,"journal":{"name":"Studies in History and Philosophy of Science","volume":"115 ","pages":"Article 102098"},"PeriodicalIF":1.8,"publicationDate":"2025-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145806311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-19DOI: 10.1016/j.shpsa.2025.102102
Denizhan Eren, Majid D. Beni
This paper examines two approaches to the measurement problem in quantum mechanics, invoking the concept of consciousness and highlighting the strengths and weaknesses of each. The first approach is the model proposed by David Chalmers and Kelvin McQueen, based on the idea of the Consciousness Collapses Wave Function (CCWF), originally attributed to John von Neumann and Eugene Wigner. The second approach is the phenomenological framework known as the London-Bauer-French (LBF) approach. We contend that significant challenges have been raised against key features of the CCWF model. However, these criticisms require further arguments to effectively undermine its most crucial claim: that the model can be tested to determine whether consciousness collapses the wave function. We will demonstrate that while CCWF offers a mathematically defined collapse mechanism that yields straightforward, experimentally testable predictions about collapse per se, these tests do not, by themselves, establish that consciousness is the cause of collapse. Nevertheless, despite this limitation, their model provides conceptual clarity in addressing the measurement problem, as it utilizes a mathematically defined collapse mechanism that offers a straightforward and testable solution. In contrast, the LBF approach lacks conceptual clarity regarding the measurement problem, as it continues to depend on the standard quantum formalism.
本文考察了量子力学中测量问题的两种方法,引用了意识的概念,并强调了每种方法的优缺点。第一种方法是由David Chalmers和Kelvin McQueen基于意识坍缩波函数(CCWF)的概念提出的模型,CCWF最初被认为是由John von Neumann和Eugene Wigner提出的。第二种方法是现象学框架,称为伦敦-鲍尔-弗伦奇(LBF)方法。我们认为,对CCWF模型的关键特征提出了重大挑战。然而,这些批评需要进一步的论证来有效地削弱其最重要的主张:该模型可以被测试以确定意识是否会使波函数崩溃。我们将证明,虽然CCWF提供了一个数学定义的坍缩机制,可以产生关于坍缩本身的直接的、实验可测试的预测,但这些测试本身并不能确定意识是坍缩的原因。然而,尽管存在这些限制,他们的模型在解决测量问题方面提供了概念上的清晰度,因为它利用了一个数学定义的坍缩机制,提供了一个直接的和可测试的解决方案。相比之下,LBF方法缺乏关于测量问题的概念清晰度,因为它继续依赖于标准量子形式主义。
{"title":"Consciousness and the measurement problem","authors":"Denizhan Eren, Majid D. Beni","doi":"10.1016/j.shpsa.2025.102102","DOIUrl":"10.1016/j.shpsa.2025.102102","url":null,"abstract":"<div><div>This paper examines two approaches to the measurement problem in quantum mechanics, invoking the concept of consciousness and highlighting the strengths and weaknesses of each. The first approach is the model proposed by David Chalmers and Kelvin McQueen, based on the idea of the Consciousness Collapses Wave Function (CCWF), originally attributed to John von Neumann and Eugene Wigner. The second approach is the phenomenological framework known as the London-Bauer-French (LBF) approach. We contend that significant challenges have been raised against key features of the CCWF model. However, these criticisms require further arguments to effectively undermine its most crucial claim: that the model can be tested to determine whether consciousness collapses the wave function. We will demonstrate that while CCWF offers a mathematically defined <strong>collapse</strong> mechanism that yields straightforward, experimentally testable predictions about collapse <strong>per se</strong>, these tests do not, by themselves, establish that <strong>consciousness</strong> is the cause of collapse. Nevertheless, despite this limitation, their model provides conceptual clarity in addressing the measurement problem, as it utilizes a mathematically defined collapse mechanism that offers a straightforward and testable solution. In contrast, the LBF approach lacks conceptual clarity regarding the measurement problem, as it continues to depend on the standard quantum formalism.</div></div>","PeriodicalId":49467,"journal":{"name":"Studies in History and Philosophy of Science","volume":"115 ","pages":"Article 102102"},"PeriodicalIF":1.8,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145792137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-18DOI: 10.1016/j.shpsa.2025.102096
Simon Lohse
I analyse arguments for social emergentism based on the notion of unpredictability. After examining and ultimately rejecting weak emergentism as relevant theoretical counterpart to (predictive) reductionism, I discuss three arguments asserting that social phenomena should be considered strongly emergent as they are in-principle unpredictable. The main results are a clearer grasp of the premises underlying an emergentist case for unpredictability and that none of the discussed arguments succeeds when confronted with the actual practice of contemporary social science. This conclusion contributes to a deeper understanding of the concept of unpredictability and the prospects of a theory of emergence in social science.
{"title":"Social emergence and unpredictability","authors":"Simon Lohse","doi":"10.1016/j.shpsa.2025.102096","DOIUrl":"10.1016/j.shpsa.2025.102096","url":null,"abstract":"<div><div>I analyse arguments for social emergentism based on the notion of unpredictability. After examining and ultimately rejecting weak emergentism as relevant theoretical counterpart to (predictive) reductionism, I discuss three arguments asserting that social phenomena should be considered strongly emergent as they are in-principle unpredictable. The main results are a clearer grasp of the premises underlying an emergentist case for unpredictability and that none of the discussed arguments succeeds when confronted with the actual practice of contemporary social science. This conclusion contributes to a deeper understanding of the concept of unpredictability and the prospects of a theory of emergence in social science.</div></div>","PeriodicalId":49467,"journal":{"name":"Studies in History and Philosophy of Science","volume":"115 ","pages":"Article 102096"},"PeriodicalIF":1.8,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145766168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.shpsa.2025.102072
Jan Cornelius Schmidt
{"title":"Reply by the Author","authors":"Jan Cornelius Schmidt","doi":"10.1016/j.shpsa.2025.102072","DOIUrl":"10.1016/j.shpsa.2025.102072","url":null,"abstract":"","PeriodicalId":49467,"journal":{"name":"Studies in History and Philosophy of Science","volume":"114 ","pages":"Article 102072"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145684679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1016/j.shpsa.2025.102073
Paola Castaño , Sabina Leonelli
The boundaries between targeted interventions, background factors, and confounders are concerns in all biological experimentation. Plant space biology takes these concerns to new territories not just geographically but also epistemically because of the operational constraints of collecting data in the multi-stressor spaceflight environment. In consequence, a central challenge in this field is the disentanglement of the various factors involved in the experiments and their tracing to biological effects on the plants.
This paper characterizes the unique challenges of fundamental plant biology experiments and examines how secondary data analysis relying on metadata curation is providing novel ways to interpret, compare, and potentially integrate results obtained in these experiments. We propose an understanding of metadata workflows in comparative analyses of complex datasets as a form of post hoc experimental control that makes data tractable for interpretation in three ways: by providing a picture of the relevant intervening factors in experiments, refining the realm of comparison by keeping some conditions constant as background and others targets of analysis, and distinguishing between dependent and independent variables. More broadly, we maintain that this work can be regarded as an extension of experimental practice as it restructures the empirical resources on which researchers build analyses of past experiments and can contribute to the design of future ones.
{"title":"Understanding the ‘spaceflight treatment’ in plant space biology: Experimental practices, metadata workflows, and data re-analysis","authors":"Paola Castaño , Sabina Leonelli","doi":"10.1016/j.shpsa.2025.102073","DOIUrl":"10.1016/j.shpsa.2025.102073","url":null,"abstract":"<div><div>The boundaries between targeted interventions, background factors, and confounders are concerns in all biological experimentation. Plant space biology takes these concerns to new territories not just geographically but also epistemically because of the operational constraints of collecting data in the multi-stressor spaceflight environment. In consequence, a central challenge in this field is the disentanglement of the various factors involved in the experiments and their tracing to biological effects on the plants.</div><div>This paper characterizes the unique challenges of fundamental plant biology experiments and examines how secondary data analysis relying on metadata curation is providing novel ways to interpret, compare, and potentially integrate results obtained in these experiments. We propose an understanding of metadata workflows in comparative analyses of complex datasets as a form of <em>post hoc</em> experimental control that makes data tractable for interpretation in three ways: by providing a picture of the relevant intervening factors in experiments, refining the realm of comparison by keeping some conditions constant as background and others targets of analysis, and distinguishing between dependent and independent variables. More broadly, we maintain that this work can be regarded as an extension of experimental practice as it restructures the empirical resources on which researchers build analyses of past experiments and can contribute to the design of future ones.</div></div>","PeriodicalId":49467,"journal":{"name":"Studies in History and Philosophy of Science","volume":"114 ","pages":"Article 102073"},"PeriodicalIF":1.8,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145514852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.shpsa.2025.102088
Mauricio Suárez
{"title":"","authors":"Mauricio Suárez","doi":"10.1016/j.shpsa.2025.102088","DOIUrl":"10.1016/j.shpsa.2025.102088","url":null,"abstract":"","PeriodicalId":49467,"journal":{"name":"Studies in History and Philosophy of Science","volume":"114 ","pages":"Article 102088"},"PeriodicalIF":1.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145466736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-31DOI: 10.1016/j.shpsa.2025.102077
Kohei Morita
Intertheoretical relationships have been traditionally investigated through the notions of reduction and emergence. Recently, the focus has shifted towards the relationship between models for elaborating intertheoretical relationships in physics. This article demonstrates that three, rather than two, types of models are essential for elucidating some intertheoretical relationships. Beyond the conventional higher- and lower-level models, an intermediate-level model is crucial for establishing connections between the theories. This framework is not only applicable to some practical cases but also effectively captures the characteristics of two significant intertheoretical relationships: between classical and quantum mechanics, and between thermodynamics and statistical mechanics. By applying this framework to these cases, this study highlights both the similarity and the difference in these intertheoretical relationships.
{"title":"Intertheoretical relationships based on three-model framework","authors":"Kohei Morita","doi":"10.1016/j.shpsa.2025.102077","DOIUrl":"10.1016/j.shpsa.2025.102077","url":null,"abstract":"<div><div>Intertheoretical relationships have been traditionally investigated through the notions of reduction and emergence. Recently, the focus has shifted towards the relationship between models for elaborating intertheoretical relationships in physics. This article demonstrates that three, rather than two, types of models are essential for elucidating some intertheoretical relationships. Beyond the conventional higher- and lower-level models, an intermediate-level model is crucial for establishing connections between the theories. This framework is not only applicable to some practical cases but also effectively captures the characteristics of two significant intertheoretical relationships: between classical and quantum mechanics, and between thermodynamics and statistical mechanics. By applying this framework to these cases, this study highlights both the similarity and the difference in these intertheoretical relationships.</div></div>","PeriodicalId":49467,"journal":{"name":"Studies in History and Philosophy of Science","volume":"114 ","pages":"Article 102077"},"PeriodicalIF":1.8,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145419172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-30DOI: 10.1016/j.shpsa.2025.102075
Juliette Ferry-Danini
This paper sets to explain how one of the most prescribed and sold pharmaceutical drugs in France – Spasfon (phloroglucinol), introduced on the French market in the 1960s, became and remained so successful in the absence of solid scientific evidence. Integrating the epistemology of ignorance and a feminist approach to the history of medicine, my goal is to understand how this case of ignorance was initially constructed and how it has maintained itself to this day. I argue that sexism is one key factor explaining how ignorance was constructed around this very popular – and incidentally pink – pharmaceutical drug.
{"title":"A pink lie in French medicine","authors":"Juliette Ferry-Danini","doi":"10.1016/j.shpsa.2025.102075","DOIUrl":"10.1016/j.shpsa.2025.102075","url":null,"abstract":"<div><div>This paper sets to explain how one of the most prescribed and sold pharmaceutical drugs in France – Spasfon (phloroglucinol), introduced on the French market in the 1960s, became and remained so successful in the absence of solid scientific evidence. Integrating the epistemology of ignorance and a feminist approach to the history of medicine, my goal is to understand how this case of ignorance was initially constructed and how it has maintained itself to this day. I argue that sexism is one key factor explaining how ignorance was constructed around this very popular – and incidentally pink – pharmaceutical drug.</div></div>","PeriodicalId":49467,"journal":{"name":"Studies in History and Philosophy of Science","volume":"114 ","pages":"Article 102075"},"PeriodicalIF":1.8,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145419171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-30DOI: 10.1016/j.shpsa.2025.102085
Chiara Ambrosio
{"title":"","authors":"Chiara Ambrosio","doi":"10.1016/j.shpsa.2025.102085","DOIUrl":"10.1016/j.shpsa.2025.102085","url":null,"abstract":"","PeriodicalId":49467,"journal":{"name":"Studies in History and Philosophy of Science","volume":"114 ","pages":"Article 102085"},"PeriodicalIF":1.8,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145419311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-30DOI: 10.1016/j.shpsa.2025.102086
Alexander Bird
{"title":"","authors":"Alexander Bird","doi":"10.1016/j.shpsa.2025.102086","DOIUrl":"10.1016/j.shpsa.2025.102086","url":null,"abstract":"","PeriodicalId":49467,"journal":{"name":"Studies in History and Philosophy of Science","volume":"114 ","pages":"Article 102086"},"PeriodicalIF":1.8,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145419310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}