Pub Date : 2025-02-03DOI: 10.1016/j.jpsychores.2025.112049
Lingfeng Chen , Mengge Zhang , Shate Xiang , Jingjing Zhang , Runyu Chang , Chao Hu , Suhai Qian , Ting Liu , Yufeng Shi , Xinghong Ding
Objective
We conducted a meta-analysis and Mendelian randomization study to analyze the association and causal relationship of genetic prediction between post-traumatic stress disorder and the risk of systemic lupus erythematosus.
Methods
A meta-analysis was conducted using hazard ratio, relative risk, odds ratio, and 95 % confidence intervals as effect measures. Summary data from genome-wide association studies on post-traumatic stress disorder and systemic lupus erythematosus were utilized to assess the causal relationship of genetic prediction between post-traumatic stress disorder and systemic lupus erythematosus using Mendelian randomization.
Results
A meta-analysis showed that post-traumatic stress disorder was positively associated with the risk of systemic lupus erythematosus (RR = 1.85, 95 % CI = 1.61–2.12, p < 0.001). The results of Egger's test showed no publication bias (p = 0.823, p > 0.05). Sensitivity analysis showed that the meta-analysis results were stable (RR = 1.85, 95 % CI = 1.61–2.12). However, Mendelian Randomization analysis revealed no evidence of a causal relationship of genetic prediction between post-traumatic stress disorder and systemic lupus erythematosus (IVW OR: 1.001, 95 % CI: 0.805–1.245, p = 0.993).
Conclusion
There is a correlation between post-traumatic stress disorder and systemic lupus erythematosus, but Mendelian Randomization does not support a genetic causal effect of post-traumatic stress disorder on systemic lupus erythematosus. The potential causal relationship between the two factors may necessitate further in-depth research.
{"title":"Post-traumatic stress disorder and risk of systemic lupus erythematosus: Meta-analysis and Mendelian randomization study","authors":"Lingfeng Chen , Mengge Zhang , Shate Xiang , Jingjing Zhang , Runyu Chang , Chao Hu , Suhai Qian , Ting Liu , Yufeng Shi , Xinghong Ding","doi":"10.1016/j.jpsychores.2025.112049","DOIUrl":"10.1016/j.jpsychores.2025.112049","url":null,"abstract":"<div><h3>Objective</h3><div>We conducted a meta-analysis and Mendelian randomization study to analyze the association and causal relationship of genetic prediction between post-traumatic stress disorder and the risk of systemic lupus erythematosus.</div></div><div><h3>Methods</h3><div>A meta-analysis was conducted using hazard ratio, relative risk, odds ratio, and 95 % confidence intervals as effect measures. Summary data from genome-wide association studies on post-traumatic stress disorder and systemic lupus erythematosus were utilized to assess the causal relationship of genetic prediction between post-traumatic stress disorder and systemic lupus erythematosus using Mendelian randomization.</div></div><div><h3>Results</h3><div>A meta-analysis showed that post-traumatic stress disorder was positively associated with the risk of systemic lupus erythematosus (RR = 1.85, 95 % CI = 1.61–2.12, <em>p</em> < 0.001). The results of Egger's test showed no publication bias (<em>p</em> = 0.823, <em>p</em> > 0.05). Sensitivity analysis showed that the meta-analysis results were stable (RR = 1.85, 95 % CI = 1.61–2.12). However, Mendelian Randomization analysis revealed no evidence of a causal relationship of genetic prediction between post-traumatic stress disorder and systemic lupus erythematosus (IVW OR: 1.001, 95 % CI: 0.805–1.245, <em>p</em> = 0.993).</div></div><div><h3>Conclusion</h3><div>There is a correlation between post-traumatic stress disorder and systemic lupus erythematosus, but Mendelian Randomization does not support a genetic causal effect of post-traumatic stress disorder on systemic lupus erythematosus. The potential causal relationship between the two factors may necessitate further in-depth research.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"190 ","pages":"Article 112049"},"PeriodicalIF":3.5,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by multisystem, including neuropsychiatric, involvement. The nervous system is affected in 20–27 % of patients within approximately two years after diagnosis. This study aimed to examine neurocognitive impairment in childhood-onset SLE (cSLE) patients before the development of any neurological, psychiatric, or cognitive manifestations.
Methods
The study included 98 children and adolescents. Of these, 34 (35 %) were cSLE groups, and the remaining formed two control groups: 31 (31 %) oligoarticular Juvenile Idiopathic Arthritis (oJIA) patients served as a “patient control” group, and 33 (34 %) healthy participants socio-demographically matched to the cSLE and oJIA patients formed the healthy control (HC) group. None of the subjects in the study exhibited neurological or psychiatric symptoms.
Results
The Wechsler Intelligence Scale for Children-IV (WISC-IV) was applied to all groups. Test results showed that the Perceptual Reasoning Index Score (PRIS) was significantly lower in cSLE than in HC (F(2, 95) = 3.365, p = 0.042, Tukey HSD: p = 0.01). ‘Comprehension’ subtest scores were significantly lower in the cSLE group compared to the HC group (H(2) = 8.133, p = 0.017; U = 352.5, p = 0.009). Similarly, ‘symbol search’ subtest scores were significantly lower in the cSLE group compared to the HC group (F(2, 95) = 3.545, p = 0.036, Tukey HSD: p = 0.014).
Conclusion
Our results revealed that cSLE may have neurocognitive impairment without presenting any symptoms. Early detection is possible with the neurocognitive test WISC-IV. These results support the inclusion of objective neurocognitive assessment methods into the routine clinical follow-up of childhood-onset SLE.
目的：系统性红斑狼疮（SLE）是一种多系统自身免疫性疾病，包括神经精神系统。20- 27%的患者在诊断后大约两年内神经系统受到影响。本研究旨在检查儿童期SLE （cSLE）患者在出现任何神经、精神或认知表现之前的神经认知障碍。方法：研究对象为98名儿童和青少年。其中34例（35%）为cSLE组，其余组成两个对照组：31例（31%）少关节幼年特发性关节炎（oJIA）患者作为“患者对照组”，33例（34%）社会人口统计学上与cSLE和oJIA患者相匹配的健康参与者组成健康对照组（HC）组。研究中没有受试者表现出神经或精神症状。结果：各组采用韦氏儿童智力量表（WISC-IV）。结果显示，cSLE患者的知觉推理指数得分（PRIS）显著低于HC患者（F(2,95) = 3.365, p = 0.042, Tukey HSD: p = 0.01）。cSLE组“理解”子测试得分显著低于HC组(H(2) = 8.133, p = 0.017；U = 352.5, p = 0.009)。同样，与HC组相比，cSLE组的“符号搜索”子测试得分显著低于HC组（F(2,95) = 3.545, p = 0.036, Tukey HSD: p = 0.014）。结论：我们的研究结果显示，cSLE可能有神经认知障碍，但没有任何症状。神经认知测试WISC-IV可以早期发现。这些结果支持将客观的神经认知评估方法纳入儿童期SLE的常规临床随访。
{"title":"Assessing cognitive functions in non-neuropsychiatric childhood systemic lupus erythematosus: Cross-sectional study","authors":"Emil Aliyev , Ecem Selin Akbas Aliyev , Selcan Demir , Mubeccel Yeniada Kirseven , Cihat Celik , Ozlem Kahraman Erkus , Halime Tuna Cak Esen , Ebru Cengel Kultur , Banu Anlar , Seza Ozen , Yelda Bilginer","doi":"10.1016/j.jpsychores.2024.112027","DOIUrl":"10.1016/j.jpsychores.2024.112027","url":null,"abstract":"<div><h3>Objectives</h3><div>Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by multisystem, including neuropsychiatric, involvement. The nervous system is affected in 20–27 % of patients within approximately two years after diagnosis. This study aimed to examine neurocognitive impairment in childhood-onset SLE (cSLE) patients before the development of any neurological, psychiatric, or cognitive manifestations.</div></div><div><h3>Methods</h3><div>The study included 98 children and adolescents. Of these, 34 (35 %) were cSLE groups, and the remaining formed two control groups: 31 (31 %) oligoarticular Juvenile Idiopathic Arthritis (oJIA) patients served as a “patient control” group, and 33 (34 %) healthy participants socio-demographically matched to the cSLE and oJIA patients formed the healthy control (HC) group. None of the subjects in the study exhibited neurological or psychiatric symptoms.</div></div><div><h3>Results</h3><div>The Wechsler Intelligence Scale for Children-IV (WISC-IV) was applied to all groups. Test results showed that the Perceptual Reasoning Index Score (PRIS) was significantly lower in cSLE than in HC (F(2, 95) = 3.365, <em>p</em> = 0.042, Tukey HSD: <em>p</em> = 0.01). ‘Comprehension’ subtest scores were significantly lower in the cSLE group compared to the HC group (H(2) = 8.133, <em>p</em> = 0.017; U = 352.5, <em>p</em> = 0.009). Similarly, ‘symbol search’ subtest scores were significantly lower in the cSLE group compared to the HC group (F(2, 95) = 3.545, <em>p</em> = 0.036, Tukey HSD: <em>p</em> = 0.014).</div></div><div><h3>Conclusion</h3><div>Our results revealed that cSLE may have neurocognitive impairment without presenting any symptoms. Early detection is possible with the neurocognitive test WISC-IV. These results support the inclusion of objective neurocognitive assessment methods into the routine clinical follow-up of childhood-onset SLE.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112027"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jpsychores.2024.111998
M. Trott , A. Koblitz , S. Pardhan
Background
Sensory impairments can negatively affect people's quality of life and daily functioning, including anxiety and depression symptoms. Cognitive behavioural therapy (CBT) could be an effective intervention to alleviate these, however its effectiveness compared to other interventions have not been examined. The aim of this review was to examine the effectiveness of CBT versus other interventions on anxiety and depression symptoms in people with hearing, visual, and other sensory impairments.
Methods
This systematic review and meta-analysis of randomised controlled trials (RCTs) was conducted using a pre-registered protocol (Prospero ID:CRD42023425953). Searches were conducted in across six databases from inception through October 2024. Random-effects meta-analyses were performed.
Results
Of 18 included studies, interventions for tinnitus yielded a significant effect favouring intervention on anxiety (Hedge's g = 0.5;95 %CI0.3–0.9) and depression symptoms (Hedge's g = 0.4; 95 %CI 0.1–0.6). Interventions for people with hearing loss not related to tinnitus yielded a significant effect favouring intervention on anxiety symptoms (Hedge's g = 0.6;95 %CI 0.2–1.1), but not in depression symptoms (Hedge's g = 0.3;95 %CI -0.0;0.6). When sub-grouped, no significant differences between CBT and other interventions were found. Interventions for people with vision impairment yielded a non-significant difference in depression symptoms (Hedge's g = 0.4;95 %CI -0.0;0.7), with no studies found examining anxiety symptoms.
Conclusion
No significant differences were found when comparing CBT versus other interventions in hearing loss. The effectiveness of CBT for people with visual impairment was less clear due to a small number of studies. Future studies should consider other types of sensory impairments.
背景：感觉障碍会对人们的生活质量和日常功能产生负面影响，包括焦虑和抑郁症状。认知行为疗法（CBT）可能是一种有效的干预措施，但与其他干预措施相比，其有效性尚未得到检验。本综述的目的是检查CBT与其他干预措施相比对听力、视觉和其他感觉障碍患者焦虑和抑郁症状的有效性。方法：采用预先注册的方案（Prospero ID:CRD42023425953）对随机对照试验（rct）进行系统评价和荟萃分析。从开始到2024年10月，在六个数据库中进行了搜索。进行随机效应荟萃分析。结果：在纳入的18项研究中，对耳鸣的干预对焦虑（Hedge’s g = 0.5; 95% CI0.3-0.9）和抑郁症状(Hedge’s g = 0.4；95% ci 0.1-0.6)。对与耳鸣无关的听力损失患者进行干预，对焦虑症状的干预效果显著（Hedge’s g = 0.6; 95% CI 0.2-1.1），但对抑郁症状的干预效果不显著（Hedge’s g = 0.3; 95% CI -0.0;0.6）。当进行分组时，发现CBT与其他干预措施之间没有显著差异。对视力受损人群的干预在抑郁症状方面没有显著差异（Hedge’s g = 0.4; 95% CI -0.0;0.7），没有研究发现检查焦虑症状。结论：CBT与其他干预措施对听力损失的影响无显著差异。由于研究较少，CBT对视力障碍患者的有效性尚不清楚。未来的研究应该考虑其他类型的感觉障碍。
{"title":"Cognitive behavioural therapy versus other interventions on mental health in people with sensory impairments: A systematic review and meta-analysis","authors":"M. Trott , A. Koblitz , S. Pardhan","doi":"10.1016/j.jpsychores.2024.111998","DOIUrl":"10.1016/j.jpsychores.2024.111998","url":null,"abstract":"<div><h3>Background</h3><div>Sensory impairments can negatively affect people's quality of life and daily functioning, including anxiety and depression symptoms. Cognitive behavioural therapy (CBT) could be an effective intervention to alleviate these, however its effectiveness compared to other interventions have not been examined. The aim of this review was to examine the effectiveness of CBT versus other interventions on anxiety and depression symptoms in people with hearing, visual, and other sensory impairments.</div></div><div><h3>Methods</h3><div>This systematic review and meta-analysis of randomised controlled trials (RCTs) was conducted using a pre-registered protocol (Prospero ID:CRD42023425953). Searches were conducted in across six databases from inception through October 2024. Random-effects meta-analyses were performed.</div></div><div><h3>Results</h3><div>Of 18 included studies, interventions for tinnitus yielded a significant effect favouring intervention on anxiety (Hedge's <em>g</em> = 0.5;95 %CI0.3–0.9) and depression symptoms (Hedge's <em>g</em> = 0.4; 95 %CI 0.1–0.6). Interventions for people with hearing loss not related to tinnitus yielded a significant effect favouring intervention on anxiety symptoms (Hedge's <em>g</em> = 0.6;95 %CI 0.2–1.1), but not in depression symptoms (Hedge's <em>g</em> = 0.3;95 %CI -0.0;0.6). When sub-grouped, no significant differences between CBT and other interventions were found. Interventions for people with vision impairment yielded a non-significant difference in depression symptoms (Hedge's <em>g</em> = 0.4;95 %CI -0.0;0.7), with no studies found examining anxiety symptoms.</div></div><div><h3>Conclusion</h3><div>No significant differences were found when comparing CBT versus other interventions in hearing loss. The effectiveness of CBT for people with visual impairment was less clear due to a small number of studies. Future studies should consider other types of sensory impairments.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 111998"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jpsychores.2024.111996
Chloe Leveille , Mysa Saad , Daniel Brabant , David Birnie , Karina Fonseca , Elliott Kyung Lee , Alan Douglass , Georg Northoff , Katerina Nikolitch , Julie Carrier , Stuart Fogel , Caitlin Higginson , Tetyana Kendzerska , Rebecca Robillard
Objective
Autonomic nervous system dysfunction and reduced heart rate variability (HRV) often co-exist with mood disorders, a phenomenon likely influenced by sleep disturbances. This study investigated heart rate (HR) and HRV across wake, rapid eye movement (REM) sleep, and non-REM (NREM) sleep in individuals with sleep complaints and bipolar or unipolar depressive disorder.
Methods
Polysomnographic data was retrospectively collated for 120 adult patients with sleep complaints and depressive symptoms [60 diagnosed with bipolar disorder, 60 diagnosed with a unipolar depressive disorder], and 60 healthy controls. HR and time-based HRV variables were computed on 30-s segments and averaged across the night for wake, NREM and REM sleep.
Results
Significant group by consciousness state interactions showed that the unipolar and bipolar groups had lower standard deviation of normal-to-normal intervals root mean square of successive R-R interval differences compared to controls during NREM and REM sleep, but not during wake (SDNN: F(4, 330) = 3.0, p = .021, np2 = 0.035; RMSSD: F(4, 332) = 5.8, p < .001, np2 = 0.065). The magnitude of these group differences did not vary significantly between NREM 1, NREM 2 and NREM 3 sleep. These interactions persisted after excluding individuals taking 3rd generation antipsychotic, lithium, anticonvulsant, and cardiovascular medications.
Conclusion
Although further work is required to account for the impact of psychotropic and cardiac medications, as well as manic and euthymic states, these findings suggest that the sleep-based autonomic signature of depressive states differs across different types of mood disorders and could potentially inform the development of biomarkers and therapeutic targets.
目的：自主神经系统功能障碍和心率变异性（HRV）降低常与情绪障碍共存，这一现象可能受睡眠障碍的影响。本研究调查了睡眠抱怨和双相或单相抑郁症患者在清醒、快速眼动（REM）睡眠和非快速眼动（NREM）睡眠期间的心率（HR）和HRV。方法：回顾性整理120例有睡眠主诉和抑郁症状的成年患者（60例诊断为双相情感障碍，60例诊断为单极情感障碍）和60例健康对照者的多导睡眠图数据。HR和基于时间的HRV变量在30秒的时间段内计算，并在夜间的清醒、非快速眼动和快速眼动睡眠中计算平均值。结果：单极组和双相组在非快速眼动期和快速眼动期睡眠时，正常-正常间隔的标准差（R-R间隔的均方根）低于对照组，但在清醒期无显著差异(SDNN: F(4,330) = 3.0, p = 0.021, np2 = 0.035；结论：虽然需要进一步的工作来解释精神药物和心脏药物以及躁狂和心境状态的影响，但这些发现表明，基于睡眠的抑郁状态自主信号在不同类型的情绪障碍中是不同的，这可能为生物标志物和治疗靶点的开发提供潜在的信息。
{"title":"Modulation of cardiac autonomic activity across consciousness states and levels of sleep depth in individuals with sleep complaints and bipolar disorder or unipolar depressive disorders","authors":"Chloe Leveille , Mysa Saad , Daniel Brabant , David Birnie , Karina Fonseca , Elliott Kyung Lee , Alan Douglass , Georg Northoff , Katerina Nikolitch , Julie Carrier , Stuart Fogel , Caitlin Higginson , Tetyana Kendzerska , Rebecca Robillard","doi":"10.1016/j.jpsychores.2024.111996","DOIUrl":"10.1016/j.jpsychores.2024.111996","url":null,"abstract":"<div><h3>Objective</h3><div>Autonomic nervous system dysfunction and reduced heart rate variability (HRV) often co-exist with mood disorders, a phenomenon likely influenced by sleep disturbances. This study investigated heart rate (HR) and HRV across wake, rapid eye movement (REM) sleep, and non-REM (NREM) sleep in individuals with sleep complaints and bipolar or unipolar depressive disorder.</div></div><div><h3>Methods</h3><div>Polysomnographic data was retrospectively collated for 120 adult patients with sleep complaints and depressive symptoms [60 diagnosed with bipolar disorder, 60 diagnosed with a unipolar depressive disorder], and 60 healthy controls. HR and time-based HRV variables were computed on 30-s segments and averaged across the night for wake, NREM and REM sleep.</div></div><div><h3>Results</h3><div>Significant group by consciousness state interactions showed that the unipolar and bipolar groups had lower standard deviation of normal-to-normal intervals root mean square of successive R-R interval differences compared to controls during NREM and REM sleep, but not during wake (SDNN: <em>F</em>(4, 330) = 3.0, <em>p</em> = .021, np2 = 0.035; RMSSD: <em>F</em>(4, 332) = 5.8, <em>p <</em> .001, np2 = 0.065). The magnitude of these group differences did not vary significantly between NREM 1, NREM 2 and NREM 3 sleep. These interactions persisted after excluding individuals taking 3rd generation antipsychotic, lithium, anticonvulsant, and cardiovascular medications.</div></div><div><h3>Conclusion</h3><div>Although further work is required to account for the impact of psychotropic and cardiac medications, as well as manic and euthymic states, these findings suggest that the sleep-based autonomic signature of depressive states differs across different types of mood disorders and could potentially inform the development of biomarkers and therapeutic targets.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 111996"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jpsychores.2024.112019
Björn Agvall , Junmei Miao Jonasson
Background
Myocardial infarction (MI) is a serious condition that increases with age. It is valuable to identify the reasons why some are affected, and possibly, why different personality traits can be associated with an increased or decreased risk for myocardial infarction.
Methods
This is a cross-sectional study based on wave 7 data from the Survey of Health, Ageing and Retirement in Europe (SHARE). A total of 52,231 individuals aged 50 years or older were included in the study. The Big Five personality traits constituted the main exposure variables and were analyzed separately. The value of each personality trait variable was standardized. The association between each personality trait and MI was examined by logistic regression models which were used to estimate the Odds Ratios (ORs) and 95 % Confidence Intervals (CIs).
Results
A total of 6336 participants reported having a MI in this study. The odds of MI were higher in individuals with greater Neuroticism (OR: 1.15, 95 % CI: 1.12–1.18). Higher Conscientiousness was associated with decreased odds of MI (OR: 0.96, 95 % CI: 0.94–0.99). Higher Agreeableness was associated with lower odds of MI (OR: 0.96, 95 % CI: 0.94–0.99). There were no significant associations between Openness or Extraversion and the odds of MI, respectively.
Conclusions
Higher Neuroticism was associated with increased odds of MI. Higher Agreeableness and Conscientiousness were associated with decreased odds of MI, respectively. Our study is of interest for the prevention of MI.
{"title":"The association between personality traits and myocardial infarction- A European cross-sectional study","authors":"Björn Agvall , Junmei Miao Jonasson","doi":"10.1016/j.jpsychores.2024.112019","DOIUrl":"10.1016/j.jpsychores.2024.112019","url":null,"abstract":"<div><h3>Background</h3><div>Myocardial infarction (MI) is a serious condition that increases with age. It is valuable to identify the reasons why some are affected, and possibly, why different personality traits can be associated with an increased or decreased risk for myocardial infarction.</div></div><div><h3>Methods</h3><div>This is a cross-sectional study based on wave 7 data from the Survey of Health, Ageing and Retirement in Europe (SHARE). A total of 52,231 individuals aged 50 years or older were included in the study. The Big Five personality traits constituted the main exposure variables and were analyzed separately. The value of each personality trait variable was standardized. The association between each personality trait and MI was examined by logistic regression models which were used to estimate the Odds Ratios (ORs) and 95 % Confidence Intervals (CIs).</div></div><div><h3>Results</h3><div>A total of 6336 participants reported having a MI in this study. The odds of MI were higher in individuals with greater Neuroticism (OR: 1.15, 95 % CI: 1.12–1.18). Higher Conscientiousness was associated with decreased odds of MI (OR: 0.96, 95 % CI: 0.94–0.99). Higher Agreeableness was associated with lower odds of MI (OR: 0.96, 95 % CI: 0.94–0.99). There were no significant associations between Openness or Extraversion and the odds of MI, respectively.</div></div><div><h3>Conclusions</h3><div>Higher Neuroticism was associated with increased odds of MI. Higher Agreeableness and Conscientiousness were associated with decreased odds of MI, respectively. Our study is of interest for the prevention of MI.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112019"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jpsychores.2024.112024
Michitaka Funayama , Toshihiro Taira , Yoshinori Saeki , Keiichi Uemura , Fumie Oka , On Kato , Naoko Satake , Hiraki Koishikawa , Shigeki Sato , Katsuji Nishimura
Objective
It remains unclear whether general hospitals without psychiatric wards can provide sufficient services for both physical and mental health needs, as they often lack adequate psychiatrists, primarily due to cost constraints. This article explores the relationship between the number of full-time psychiatrists and functionality for integrating physical and mental health services in these settings.
Methods
The Medical Policy Committee of the Japanese Society of General Hospital Psychiatry conducted a nationwide survey in 2022 to evaluate the detailed scope and volume of service of psychiatric departments in general hospitals without a psychiatric ward. The survey collected data related to scope and volume of service, including the availability of on-call services, the number of patients seen in outpatient settings, and the number of consultation-liaison services provided. The results were analyzed based on the number of full-time psychiatrists, with and without data from university hospitals, and categorized by hospital type. To account for confounding factors, multivariable regression analyses were also performed.
Results
Broader scope and higher vollume in essential services was observed depending on the number of full-time psychiatrists, including on-call services, outpatient services, and consultation-liaison services, especially pediatric, anorexia, and perinatal psychiatric issues. Hospitals with multiple full-time psychiatrists offered broader services, a scope beyond the capacity of a single full-time psychiatrist, as confirmed by multivariable analyses. University hospitals offered the widest range of psychiatric services.
Conclusions
Despite often being underestimated due to cost constraints, having multiple full-time psychiatrists in a general hospital without a psychiatric ward is essential for supporting the broader scope needed to integrate physical and mental health services.
{"title":"Boosting integration of physical and mental health: The impact of increasing psychiatrists in general hospitals without psychiatric Ward","authors":"Michitaka Funayama , Toshihiro Taira , Yoshinori Saeki , Keiichi Uemura , Fumie Oka , On Kato , Naoko Satake , Hiraki Koishikawa , Shigeki Sato , Katsuji Nishimura","doi":"10.1016/j.jpsychores.2024.112024","DOIUrl":"10.1016/j.jpsychores.2024.112024","url":null,"abstract":"<div><h3>Objective</h3><div>It remains unclear whether general hospitals without psychiatric wards can provide sufficient services for both physical and mental health needs, as they often lack adequate psychiatrists, primarily due to cost constraints. This article explores the relationship between the number of full-time psychiatrists and functionality for integrating physical and mental health services in these settings.</div></div><div><h3>Methods</h3><div>The Medical Policy Committee of the Japanese Society of General Hospital Psychiatry conducted a nationwide survey in 2022 to evaluate the detailed scope and volume of service of psychiatric departments in general hospitals without a psychiatric ward. The survey collected data related to scope and volume of service, including the availability of on-call services, the number of patients seen in outpatient settings, and the number of consultation-liaison services provided. The results were analyzed based on the number of full-time psychiatrists, with and without data from university hospitals, and categorized by hospital type. To account for confounding factors, multivariable regression analyses were also performed.</div></div><div><h3>Results</h3><div>Broader scope and higher vollume in essential services was observed depending on the number of full-time psychiatrists, including on-call services, outpatient services, and consultation-liaison services, especially pediatric, anorexia, and perinatal psychiatric issues. Hospitals with multiple full-time psychiatrists offered broader services, a scope beyond the capacity of a single full-time psychiatrist, as confirmed by multivariable analyses. University hospitals offered the widest range of psychiatric services.</div></div><div><h3>Conclusions</h3><div>Despite often being underestimated due to cost constraints, having multiple full-time psychiatrists in a general hospital without a psychiatric ward is essential for supporting the broader scope needed to integrate physical and mental health services.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112024"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jpsychores.2024.112032
Boxuan Pu , Wei Wang , Lubi Lei , Jingkuo Li , Yue Peng , Yanwu Yu , Lihua Zhang , Xin Yuan
Background
Depression and cardiovascular health (CVH) are interconnected, and both are independently associated with mortality. However, the joint effects of depressive symptoms and CVH on mortality remain unclear.
Methods
By utilizing the National Health and Nutrition Examination Survey (NHANES) 2007–2018, we included 18,679 adults aged ≥20 years without cardiovascular diseases (CVD). The definition of elevated depressive symptoms was based on the Patient Health Questionnaire-9 (PHQ-9) scores≥10. CVH was evaluated by Life's Essential 8 (LE8) and categorized into low (<50), moderate (50–80), or high (≥80). The joint association of depressive symptoms and CVH with mortality was examined utilizing multivariate Cox proportional hazard models.
Results
Elevated depressive symptoms were associated with higher mortality risks, and CVH could explain 12.7 % and 13.7 % of the associations between depression and all-cause and non-CVD mortality, respectively. No significant interactions were found between CVH and depressive symptoms on mortality. High CVH attenuated the all-cause mortality risk in patients with elevated depressive symptoms (HR, 0.20; 95 % CI: 0.05–0.89). Compared to participants with elevated depressive symptoms and low CVH, those with no elevated depressive symptoms and high CVH had lower risks of all-cause (HR, 0.26; 95 % CI: 0.16–0.43), CVD (HR, 0.20; 95 % CI: 0.07–0.52), non-CVD mortality (HR, 0.28; 95 % CI 0.16–0.50).
Conclusion
Adults with low CVH and elevated depressive symptoms had significantly higher risks of all-cause, CVD, and non-CVD mortality. The finding suggests considering depressive symptoms and CVH jointly in developing targeted strategies to improve survival.
{"title":"Association of depressive symptoms and cardiovascular health with mortality among U.S. adults","authors":"Boxuan Pu , Wei Wang , Lubi Lei , Jingkuo Li , Yue Peng , Yanwu Yu , Lihua Zhang , Xin Yuan","doi":"10.1016/j.jpsychores.2024.112032","DOIUrl":"10.1016/j.jpsychores.2024.112032","url":null,"abstract":"<div><h3>Background</h3><div>Depression and cardiovascular health (CVH) are interconnected, and both are independently associated with mortality. However, the joint effects of depressive symptoms and CVH on mortality remain unclear.</div></div><div><h3>Methods</h3><div>By utilizing the National Health and Nutrition Examination Survey (NHANES) 2007–2018, we included 18,679 adults aged ≥20 years without cardiovascular diseases (CVD). The definition of elevated depressive symptoms was based on the Patient Health Questionnaire-9 (PHQ-9) scores≥10. CVH was evaluated by Life's Essential 8 (LE8) and categorized into low (<50), moderate (50–80), or high (≥80). The joint association of depressive symptoms and CVH with mortality was examined utilizing multivariate Cox proportional hazard models.</div></div><div><h3>Results</h3><div>Elevated depressive symptoms were associated with higher mortality risks, and CVH could explain 12.7 % and 13.7 % of the associations between depression and all-cause and non-CVD mortality, respectively. No significant interactions were found between CVH and depressive symptoms on mortality. High CVH attenuated the all-cause mortality risk in patients with elevated depressive symptoms (HR, 0.20; 95 % CI: 0.05–0.89). Compared to participants with elevated depressive symptoms and low CVH, those with no elevated depressive symptoms and high CVH had lower risks of all-cause (HR, 0.26; 95 % CI: 0.16–0.43), CVD (HR, 0.20; 95 % CI: 0.07–0.52), non-CVD mortality (HR, 0.28; 95 % CI 0.16–0.50).</div></div><div><h3>Conclusion</h3><div>Adults with low CVH and elevated depressive symptoms had significantly higher risks of all-cause, CVD, and non-CVD mortality. The finding suggests considering depressive symptoms and CVH jointly in developing targeted strategies to improve survival.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112032"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jpsychores.2024.111984
Colette Naude , David Skvarc , Yao Coitinho Biurra , Lily Blake , Subhadra Evans , Simon Knowles , O. Eric , Chatpakorn Prasertsung , Lahiru Russell , Anna Bassili , Antonina Mikocka-Walus
Objective
The bidirectional relationship between disease activity and mental health in inflammatory bowel disease (IBD) has prompted investigations into the efficacy of psychotherapies, such as mindfulness-based interventions (MBI), for improving biopsychosocial outcomes. Therefore, the aim is to examine the feasibility, acceptability, and preliminary efficacy of an online-delivered, self-directed MBI, adapted to individuals with IBD and psychological distress, in comparison to wait-list control (WLC).
Methods
50 adults with IBD were randomized to WLC (N = 25) or intervention (N = 25) groups. The intervention (MIND4IBD program) consisted of six, weekly, 15-min videos (with guided meditations). Feasibility was examined through recruitment and retention rates, while acceptability was examined through intervention satisfaction ratings and qualitative feedback. Preliminary efficacy was examined using linear mixed models for group differences in outcomes between baseline and post-intervention.
Results
Primary Outcomes. The retention rate for the WLC group was 92 %, while the retention rate for the intervention group was 48 %. However, 16 % of participants allocated to the intervention group never began the intervention, therefore this resulted in a retention rate of 71 % of participants who began the intervention. Acceptability was high with an average intervention satisfaction rating of 83/100. Secondary Outcomes. When compared with the WLC, the MIND4IBD program improved total mindfulness levels (b = 0.29, 95 %CI [0.11,0.47], p = 0.004) with a large effect size (β = 0.54, b = 0.19, 95 %CI [0.04,0.34], p = 0.014). Themes based on participants' intervention feedback included: 1) beginning of journey with mindfulness, 2) the beneficial impact of mindfulness, 3) why adapting the intervention to IBD is important, 4) views on program delivery, and 5) mixed reactions to AI generated presenters.
Conclusion
MIND4IBD is feasible and acceptable for individuals with IBD and psychological distress. Participants' total mindfulness levels increased significantly in the intervention group compared to WLC. Most participants provided positive intervention feedback. These findings warrant a full-scale RCT to determine MIND4IBD's efficacy for IBD.
目的：炎症性肠病（IBD）患者的疾病活动与心理健康之间的双向关系促使人们研究心理治疗的疗效，如正念干预（MBI），以改善生物心理社会结果。因此，本研究的目的是检验在线交付的自我导向MBI的可行性、可接受性和初步疗效，该MBI适用于IBD和心理困扰患者，并与等候名单对照（WLC）进行比较。方法：50例成年IBD患者随机分为WLC组（N = 25）和干预组（N = 25）。干预（MIND4IBD计划）包括六个，每周，15分钟的视频（指导冥想）。可行性通过招募率和保留率来检验，可接受性通过干预满意度评分和定性反馈来检验。使用线性混合模型对基线和干预后结果的组间差异进行初步疗效检查。结果：主要结局。WLC组的保留率为92%，而干预组的保留率为48%。然而，被分配到干预组的参与者中有16%从未开始干预，因此这导致开始干预的参与者的保留率为71%。可接受性高，平均干预满意度为83/100。次要结局：与WLC相比，MIND4IBD方案提高了总正念水平（b = 0.29, 95% CI [0.11,0.47], p = 0.004），效应量大（β = 0.54, b = 0.19, 95% CI [0.04,0.34], p = 0.014）。基于参与者干预反馈的主题包括：1)正念之旅的开始，2)正念的有益影响，3)为什么使干预适应IBD很重要，4)对项目交付的看法，以及5)对人工智能生成的演示者的不同反应。结论：对于有IBD和心理困扰的个体，MIND4IBD是可行和可接受的。与WLC相比，干预组参与者的总正念水平显著提高。大多数参与者提供了积极的干预反馈。这些发现证明需要进行全面的随机对照试验来确定MIND4IBD对IBD的疗效。
{"title":"An online mindfulness-based intervention for adults with Inflammatory Bowel Disease & psychological distress: A feasibility randomized controlled trial of the Mind4IBD program","authors":"Colette Naude , David Skvarc , Yao Coitinho Biurra , Lily Blake , Subhadra Evans , Simon Knowles , O. Eric , Chatpakorn Prasertsung , Lahiru Russell , Anna Bassili , Antonina Mikocka-Walus","doi":"10.1016/j.jpsychores.2024.111984","DOIUrl":"10.1016/j.jpsychores.2024.111984","url":null,"abstract":"<div><h3>Objective</h3><div>The bidirectional relationship between disease activity and mental health in inflammatory bowel disease (IBD) has prompted investigations into the efficacy of psychotherapies, such as mindfulness-based interventions (MBI), for improving biopsychosocial outcomes. Therefore, the aim is to examine the feasibility, acceptability, and preliminary efficacy of an online-delivered, self-directed MBI, adapted to individuals with IBD and psychological distress, in comparison to wait-list control (WLC).</div></div><div><h3>Methods</h3><div>50 adults with IBD were randomized to WLC (<em>N</em> = 25) or intervention (N = 25) groups. The intervention (MIND4IBD program) consisted of six, weekly, 15-min videos (with guided meditations). Feasibility was examined through recruitment and retention rates, while acceptability was examined through intervention satisfaction ratings and qualitative feedback. Preliminary efficacy was examined using linear mixed models for group differences in outcomes between baseline and post-intervention.</div></div><div><h3>Results</h3><div>Primary Outcomes. The retention rate for the WLC group was 92 %, while the retention rate for the intervention group was 48 %. However, 16 % of participants allocated to the intervention group never began the intervention, therefore this resulted in a retention rate of 71 % of participants who began the intervention. Acceptability was high with an average intervention satisfaction rating of 83/100. Secondary Outcomes. When compared with the WLC, the MIND4IBD program improved total mindfulness levels (b = 0.29, 95 %CI [0.11,0.47], <em>p</em> = 0.004) with a large effect size (β = 0.54, b = 0.19, 95 %CI [0.04,0.34], <em>p</em> = 0.014). Themes based on participants' intervention feedback included: 1) beginning of journey with mindfulness, 2) the beneficial impact of mindfulness, 3) why adapting the intervention to IBD is important, 4) views on program delivery, and 5) mixed reactions to AI generated presenters.</div></div><div><h3>Conclusion</h3><div>MIND4IBD is feasible and acceptable for individuals with IBD and psychological distress. Participants' total mindfulness levels increased significantly in the intervention group compared to WLC. Most participants provided positive intervention feedback. These findings warrant a full-scale RCT to determine MIND4IBD's efficacy for IBD.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 111984"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jpsychores.2024.112011
Elzbieta Klimiec-Moskal, Joanna Pera, Agnieszka Slowik, Tomasz Dziedzic
Background
Delirium could increase the risk of cognitive decline. We aimed to determine if changes in cognitive functions shortly after stroke differ between patients with and patients without delirium.
Methods
We included patients who participated in the Prospective Observational Polish Study on post-stroke delirium and underwent the Montreal Cognitive Assessment (MoCA) at day 1, day 8 and 3 months after stroke. Delirium was diagnosed using DSM-5 criteria. We used mixed linear regression models to characterize changes in mean adjusted MoCA scores over time.
Results
We included 402 patients (mean age: 68.9 13.3 years; mean NIHSS on admission: 6.2 5.5; 48.8 % female). Delirium occurred in 18.9 % of them. Mean adjusted MoCA scores increased from day 1 to day 8 (20.48 vs 23.34, P < 0.001) and then declined from day 8 to month 3 (23.34 vs 22.21, P < 0.001). The rate of change in total MoCA scores from day 1 to day 8 (net effect: 0.65, 95 %CI: −1.19; 2.49, P = 0.489) and from day 8 to month 3 (net effect: -2.43, 95 %CI: −4.84; −0.02, P = 0.147) did not differ between patients with and patients without delirium. Compared with patients without delirium, those with delirium showed a greater improvement in naming, orientation and attention, accompanied by a worsening in memory from day 1 to day 8. They also experienced a greater decline in attention and orientation, along with a greater improvement in memory from day 8 to 3 months.
Conclusions
Post-stroke delirium is associated with short-term trajectories of specific cognitive domains, but not with changes in global cognition.
{"title":"Association of post-stroke delirium with short-term trajectories of cognition","authors":"Elzbieta Klimiec-Moskal, Joanna Pera, Agnieszka Slowik, Tomasz Dziedzic","doi":"10.1016/j.jpsychores.2024.112011","DOIUrl":"10.1016/j.jpsychores.2024.112011","url":null,"abstract":"<div><h3>Background</h3><div>Delirium could increase the risk of cognitive decline. We aimed to determine if changes in cognitive functions shortly after stroke differ between patients with and patients without delirium.</div></div><div><h3>Methods</h3><div>We included patients who participated in the Prospective Observational Polish Study on post-stroke delirium and underwent the Montreal Cognitive Assessment (MoCA) at day 1, day 8 and 3 months after stroke. Delirium was diagnosed using DSM-5 criteria. We used mixed linear regression models to characterize changes in mean adjusted MoCA scores over time.</div></div><div><h3>Results</h3><div>We included 402 patients (mean age: 68.9 <span><math><mo>±</mo></math></span> 13.3 years; mean NIHSS on admission: 6.2 <span><math><mo>±</mo></math></span> 5.5; 48.8 % female). Delirium occurred in 18.9 % of them. Mean adjusted MoCA scores increased from day 1 to day 8 (20.48 vs 23.34, <em>P</em> < 0.001) and then declined from day 8 to month 3 (23.34 vs 22.21, P < 0.001). The rate of change in total MoCA scores from day 1 to day 8 (net effect: 0.65, 95 %CI: −1.19; 2.49, <em>P</em> = 0.489) and from day 8 to month 3 (net effect: -2.43, 95 %CI: −4.84; −0.02, <em>P</em> = 0.147) did not differ between patients with and patients without delirium. Compared with patients without delirium, those with delirium showed a greater improvement in naming, orientation and attention, accompanied by a worsening in memory from day 1 to day 8. They also experienced a greater decline in attention and orientation, along with a greater improvement in memory from day 8 to 3 months.</div></div><div><h3>Conclusions</h3><div>Post-stroke delirium is associated with short-term trajectories of specific cognitive domains, but not with changes in global cognition.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112011"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jpsychores.2024.112012
Leah Cha, Amanda K. Montoya, Christine Dunkel Schetter, Jennifer A. Sumner
Objective
Neighborhood characteristics can influence cardiometabolic health, including during the perinatal period. However, maternal health research has largely examined the influence of objective neighborhood measures, limiting insights into psychological and social processes. We examined associations of perceived neighborhood disorder and social cohesion with maternal cardiometabolic risk 1 year postpartum and explored potential pathways of psychological distress and physical activity.
Methods
A predominantly low-income sample of Black, Latina, and White postpartum women (n = 987) were participants in the Community Child Health Network study. Women reported on neighborhood characteristics at 1 month postpartum and on symptoms of depression, anxiety, and posttraumatic stress disorder and physical activity at 6 months postpartum. Biometrics and biological samples were collected at 1 year postpartum, including blood pressure, height, weight, and dried blood spots for cardiometabolic biomarkers (e.g., C-reactive protein, glycosylated hemoglobin). In this pre-registered study, we used structural equation modeling to estimate latent variables for disorder, social cohesion, distress, physical activity, and cardiometabolic risk. We fit a parallel mediation model to test associations between latent neighborhood factors at 1 month postpartum, distress and physical activity at 6 months postpartum, and cardiometabolic risk at 1 year postpartum.
Results
Greater social cohesion, but not disorder, was significantly associated with lower distress and greater physical activity. However, there were no significant associations between disorder or social cohesion with subsequent cardiometabolic risk nor evidence for indirect effects of distress or physical activity.
Conclusion
Results suggest that social cohesion may be more pertinent than disorder for health-relevant behavioral mechanisms in postpartum women.
{"title":"Neighborhood disorder and social cohesion: A longitudinal investigation of links with maternal cardiometabolic risk one year postpartum","authors":"Leah Cha, Amanda K. Montoya, Christine Dunkel Schetter, Jennifer A. Sumner","doi":"10.1016/j.jpsychores.2024.112012","DOIUrl":"10.1016/j.jpsychores.2024.112012","url":null,"abstract":"<div><h3>Objective</h3><div>Neighborhood characteristics can influence cardiometabolic health, including during the perinatal period. However, maternal health research has largely examined the influence of objective neighborhood measures, limiting insights into psychological and social processes. We examined associations of perceived neighborhood disorder and social cohesion with maternal cardiometabolic risk 1 year postpartum and explored potential pathways of psychological distress and physical activity.</div></div><div><h3>Methods</h3><div>A predominantly low-income sample of Black, Latina, and White postpartum women (<em>n</em> = 987) were participants in the Community Child Health Network study. Women reported on neighborhood characteristics at 1 month postpartum and on symptoms of depression, anxiety, and posttraumatic stress disorder and physical activity at 6 months postpartum. Biometrics and biological samples were collected at 1 year postpartum, including blood pressure, height, weight, and dried blood spots for cardiometabolic biomarkers (e.g., C-reactive protein, glycosylated hemoglobin). In this pre-registered study, we used structural equation modeling to estimate latent variables for disorder, social cohesion, distress, physical activity, and cardiometabolic risk. We fit a parallel mediation model to test associations between latent neighborhood factors at 1 month postpartum, distress and physical activity at 6 months postpartum, and cardiometabolic risk at 1 year postpartum.</div></div><div><h3>Results</h3><div>Greater social cohesion, but not disorder, was significantly associated with lower distress and greater physical activity. However, there were no significant associations between disorder or social cohesion with subsequent cardiometabolic risk nor evidence for indirect effects of distress or physical activity.</div></div><div><h3>Conclusion</h3><div>Results suggest that social cohesion may be more pertinent than disorder for health-relevant behavioral mechanisms in postpartum women.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112012"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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