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Journal of Psychosomatic Research 2025 year in review 心身研究杂志2025年回顾。
IF 3.3 2区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-23 DOI: 10.1016/j.jpsychores.2025.112506
Fiammetta Cosci
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引用次数: 0
Age, sex and mental distress as predictors of rate and deterioration of persistent physical symptoms over three and six years in a general population 在一般人群中,年龄、性别和精神困扰作为3年和6年持续身体症状发生率和恶化的预测因素
IF 3.3 2区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-18 DOI: 10.1016/j.jpsychores.2025.112505
Karl Fjellborg , Clara Cervin , Michael Witthöft , Ferenc Köteles , Steven Nordin

Background

Better understanding for persistent physical symptoms (PPS) may improve prevention of symptoms from becoming persistent and deteriorating over time. This study tested the hypotheses of age and level of mental distress symptoms of anxiety, depression, sleep disturbance and burnout statistically predicting rate of PPS and deterioration of PPS over three and six years in a general adult population. We also addressed whether sex is associated with these two aspects of PPS.

Method

A population-based sample (n = 1837) aged 18–79 years from Västerbotten in Sweden was used. Longitudinal data were collected based on the 15-item Patient Health Questionnaire for PPS assessment as well as other validated questionnaire instruments at baseline and 3- and 6-year follow-up. Deterioration was assessed with the reliable change index paradigm. Chi-square tests and analyses of covariance were applied.

Results

Old age was found to statistically predict deterioration, but not long-term rate, of PPS over three and six years, and female sex to predict rate, but not deterioration. Symptom levels of all four types of mental distress predicted both PPS rate (η2 = 0.097–0.202) and deterioration (η2 = 0.007–0.023) over both three and six years. When controlling for the other three types of mental distress, sleep disturbance, and in particular burnout, explained most unique variance in predicting rate and deterioration.

Conclusions

The findings encourage healthcare professionals to assess PPS at an early stage, especially in persons at old age, in women and in patients with mental distress.
背景:更好地了解持续性身体症状(PPS)可能有助于预防症状随着时间的推移变得持续和恶化。本研究检验了年龄和焦虑、抑郁、睡眠障碍和倦怠等精神困扰症状水平对普通成年人3年和6年PPS发病率和PPS恶化的统计学预测假设。我们还探讨了性是否与PPS的这两个方面有关。方法采用瑞典Västerbotten年龄在18-79岁的人群为基础的样本(n = 1837)。在基线和3年和6年随访期间,通过15项患者健康问卷以及其他有效的问卷工具收集纵向数据。用可靠变化指数范式评估恶化程度。采用卡方检验和协方差分析。结果年龄对3年和6年PPS的恶化有统计学意义,但对远期发病率无统计学意义;性别对PPS的恶化无统计学意义。在3年和6年期间,所有四种精神困扰的症状水平均可预测PPS发生率(η2 = 0.097 ~ 0.202)和病情恶化(η2 = 0.007 ~ 0.023)。当控制其他三种类型的精神困扰时,睡眠障碍,特别是倦怠,解释了预测率和恶化的最独特的方差。结论:研究结果鼓励医疗保健专业人员在早期阶段评估PPS,特别是在老年人、妇女和精神困扰患者中。
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引用次数: 0
A longitudinal latent class analysis of health-related quality of life post pelvic fractures; the BIOS cohort study 骨盆骨折后健康相关生活质量的纵向潜类分析BIOS队列研究
IF 3.3 2区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-18 DOI: 10.1016/j.jpsychores.2025.112504
Maartje L.V. Kusters , Nina Kupper , Lars Brouwers , Mariska A.C. de Jongh

Background

The objective of this study was to identify latent profiles in the HRQoL recovery of patients with pelvic fractures and examine demographic, psychological, and medical determinants.

Methods

184 patients (Mage = 58.3 ± 16.9, 59 % male) from the BIOS study were included. HRQoL was assessed six times across two years. At 1-week post-injury, additional pre-injury HRQoL (EQ-5D-3L), psychological (HADS, IES), and functional (MPS, MAHS) measures were assessed. A 3-step repeated measures latent class analysis (RMLCA) identified latent profiles in HRQoL and examined their correlates.

Results

Four similar recovery profiles for the EQ-5D domains of VAS, mobility, and usual activities were identified: low/poor, intermediate/partial, high/full, and prominent improvement/fast & full recovery. For the EQ-5D domains of pain/discomfort, self-care, and anxiety/depression, three similar profiles were identified: poor recovery, partial recovery/intermediate problems, and full recovery/ no pain. Higher emotional distress, comorbidities, and complications were associated with the low VAS profile. Older age, pelvic ring fracture, pelvic surgery, higher ISS, lower emotional distress, and higher pre-injury HRQoL levels were associated with the prominent improvement VAS profile. Better physical functioning was associated with the intermediate and high VAS profiles.

Conclusions

Results unveiled person-level heterogeneity evidenced by the four latent recovery trajectories of HRQoL following pelvic fracture and their distinct associated covariates, among which psychological functioning, which significantly contributed to HRQoL recovery. Future research should focus on the development of adequate screening tools facilitating decision-making applications which in turn can optimize personalized treatment programs. The current findings offer valuable insights to aid in this developmental process.
本研究的目的是确定骨盆骨折患者HRQoL恢复的潜在特征,并检查人口统计学、心理和医学决定因素。方法纳入184例BIOS患者(年龄≥58.3±16.9,男性59%)。HRQoL在两年内评估了六次。在损伤后1周,评估其他损伤前HRQoL (EQ-5D-3L)、心理(HADS、IES)和功能(MPS、MAHS)指标。采用3步重复测量潜类分析(RMLCA)确定HRQoL的潜类特征,并检验其相关性。结果在VAS的EQ-5D域、可动性和日常活动方面有4个相似的恢复特征:低/差、中/部分、高/完全和显著改善/快速和完全恢复。对于疼痛/不适、自我照顾和焦虑/抑郁的EQ-5D领域,确定了三种相似的特征:恢复不良、部分恢复/中度问题和完全恢复/无疼痛。较高的情绪困扰、合并症和并发症与较低的VAS评分有关。年龄较大、骨盆环骨折、骨盆手术、较高的ISS、较低的情绪困扰和较高的损伤前HRQoL水平与VAS评分显著改善相关。较好的身体功能与中高VAS评分相关。结论骨盆骨折后HRQoL的四个潜在恢复轨迹及其不同的相关协变量显示了个体水平的异质性,其中心理功能对HRQoL的恢复有显著影响。未来的研究应侧重于开发适当的筛查工具,以促进决策应用,从而优化个性化的治疗方案。目前的研究结果为这一发展过程提供了有价值的见解。
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引用次数: 0
Personality traits as predictors of self-care agency in women with gynecological cancers: Cross-sectional study 人格特质作为妇科癌症患者自我照顾能力的预测因子:横断面研究
IF 3.3 2区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-18 DOI: 10.1016/j.jpsychores.2025.112503
Huri Çolu , Elif Uludağ

Background

Gynecological cancers present a dual burden of physiological and psychosocial distress. Self-care agency defined as an individual's capacity to initiate and maintain health-related behaviors is critical for optimizing well-being in cancer patients. While psychological factors, particularly personality traits, are known to influence self-care in chronic illnesses, their role in gynecological oncology remains underexplored. This study aimed to determine whether personality traits predict self-care agency among women with gynecological cancers.

Methods

A descriptive, cross-sectional design was employed with 200 women recruited via convenience sampling. Data were collected using a demographic form, the Cervantes Personality Scale, and the Exercise of Self-Care Agency Scale. Simple linear regression analyses examined the predictive value of personality subscales on self-care agency.

Results

Personality traits were found to be significant predictors of self-care agency. Extroversion, emotional stability, and consistency explained 37.5 %, 20.1 %, and 30.4 % of the variance in self-care agency, respectively (p < 0.05). Women with higher levels of these traits demonstrated greater self-care capacity, while introversion, neuroticism, and inconsistency were linked to reduced self-care agency.

Conclusions

This study highlights the significant role of personality traits in influencing self-care agency in this population. Tailoring supportive care to address individual personality characteristics may improve self-management and overall treatment outcomes. Incorporating psychosocial assessments into routine care and developing targeted interventions could enhance quality of life. Future research should focus on intervention studies to validate these approaches and optimize personalized care strategies in gynecological oncology.
妇科癌症呈现出生理和社会心理困扰的双重负担。自我保健机构被定义为个人发起和维持与健康有关的行为的能力,对优化癌症患者的福祉至关重要。虽然心理因素,特别是人格特征,已知会影响慢性疾病患者的自我护理,但它们在妇科肿瘤中的作用仍未得到充分探讨。本研究旨在确定人格特征是否能预测妇科癌症患者的自我照顾能力。方法采用描述性、横断面设计,采用方便抽样方法对200名妇女进行调查。数据收集使用人口统计形式,塞万提斯人格量表和自我照顾代理量表的行使。简单线性回归分析了人格分量表对自我照顾能动性的预测价值。结果人格特质是自我照顾能动性的显著预测因子。外向性、情绪稳定性和一致性分别解释了37.5%、20.1%和30.4%的自我照顾能力方差(p < 0.05)。这些特征水平较高的女性表现出更强的自我照顾能力,而内向、神经质和不一致则与自我照顾能力下降有关。结论本研究强调了人格特质对该人群自我照顾能力的重要影响。针对个体个性特征定制支持性护理可以改善自我管理和整体治疗结果。将心理社会评估纳入日常护理并制定有针对性的干预措施可以提高生活质量。未来的研究应侧重于干预研究,以验证这些方法并优化妇科肿瘤的个性化护理策略。
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引用次数: 0
Non-pharmacological palliative interventions for cancer-related pain and fatigue: A network meta-analysis 癌症相关疼痛和疲劳的非药物姑息性干预:网络荟萃分析。
IF 3.3 2区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-17 DOI: 10.1016/j.jpsychores.2025.112501
Yan Adi Wibawa , Tsai-Wei Huang , Yan Wisnu Prajoko , Made Satya Nugraha Gautama , Sri Setyowati , Enggar Purnaningsih , Sri Indah Ekowati , Endang Fatmawati , Indriyani , Nur Aini , Fitria Endah Janitra
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引用次数: 0
Corrigendum to “Functional neuroimaging in patients with catatonia: A systematic review”. [Journal of Psychosomatic Research. 179 (2024) 111640] “紧张症患者的功能性神经影像学:系统回顾”的勘误表。心身研究,179(2024)111640。
IF 3.3 2区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-15 DOI: 10.1016/j.jpsychores.2025.112497
Laura Duque , Mohammad Ghafouri , Nicolas A. Nunez , Juan Pablo Ospina , Kemuel L. Philbrick , John D. Port , Rodolfo Savica , Larry J. Prokop , Teresa A. Rummans , Balwinder Singh
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引用次数: 0
Single-arm longitudinal study to assess changes in insula functional connectivity following a mobile-based lifestyle intervention in adults with metabolic abnormalities 单臂纵向研究评估代谢异常成人在移动生活方式干预后脑岛功能连通性的变化。
IF 3.3 2区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-14 DOI: 10.1016/j.jpsychores.2025.112498
Deokjong Lee , Kyung Mee Park , Jihye Kim , Sin Young Ko , Byeonghee Lee , Chae Jung Park , Kyoung Min Kim , Jin Young Park

Backgrounds

Mobile-based lifestyle intervention has been widely used to improve behavior for obesity and overweight. This study targeting adults with metabolic abnormalities aims to identify neural correlates related to weight loss due to mobile-based lifestyle intervention.

Methods

We conducted 8 weeks of mobile-based lifestyle intervention for 37 adults with metabolic abnormalities, including overweight. Participants underwent physical measurements, blood tests, psychometric questionnaires, and resting-state functional magnetic resonance imaging (fMRI) scans before and after the mobile-based intervention. For the resting-state fMRI, brain regions that showed changes in functional connectivity (FC) before and after mobile-based intervention were explored. Seed-based FC analysis was performed focusing on the subregions of the insular cortex.

Results

Participants significantly reduced body mass index (BMI) after mobile-based intervention. The degree of BMI reduction was significantly correlated with compliance with the intervention. In resting fMRI, FC of the posterior insula with the bilateral inferior parietal lobule and the left ventrolateral prefrontal cortex were enhanced after mobile-based intervention. The increase in FC between the posterior insula and the inferior posterior lobule showed a significant correlation with the decrease in binge eating scale scores.

Conclusion

The mobile-based lifestyle intervention significantly reduced weight and alleviated binge eating in adults with metabolic abnormalities. FC enhancement between the posterior insula and the frontoparietal regions was also observed after mobile-based lifestyle intervention. The relationship between these FC changes and strengthening weight control through mobile-based lifestyle intervention should be investigated through future research.
背景:基于手机的生活方式干预已被广泛用于改善肥胖和超重的行为。这项针对成人代谢异常的研究旨在确定基于移动的生活方式干预与体重减轻相关的神经相关性。方法:我们对37名代谢异常(包括超重)的成年人进行了8周的基于移动的生活方式干预。参与者在移动干预前后接受了身体测量、血液测试、心理测量问卷和静息状态功能磁共振成像(fMRI)扫描。对于静息状态fMRI,研究人员探索了在基于移动的干预前后显示功能连接(FC)变化的大脑区域。基于种子的FC分析集中在岛叶皮层的亚区。结果:参与者在移动干预后显著降低了身体质量指数(BMI)。BMI降低程度与干预依从性显著相关。静息fMRI显示,运动干预后,脑岛后部与双侧下顶叶和左腹外侧前额叶皮层的FC增强。后岛叶和下后小叶之间FC的增加与暴食量表得分的下降有显著相关。结论:以移动为基础的生活方式干预可显著减轻代谢异常成人的体重和暴饮暴食。在以移动为基础的生活方式干预后,也观察到脑岛后部和额顶叶区域之间的FC增强。这些FC变化与通过基于移动的生活方式干预加强体重控制之间的关系应该通过未来的研究来调查。
{"title":"Single-arm longitudinal study to assess changes in insula functional connectivity following a mobile-based lifestyle intervention in adults with metabolic abnormalities","authors":"Deokjong Lee ,&nbsp;Kyung Mee Park ,&nbsp;Jihye Kim ,&nbsp;Sin Young Ko ,&nbsp;Byeonghee Lee ,&nbsp;Chae Jung Park ,&nbsp;Kyoung Min Kim ,&nbsp;Jin Young Park","doi":"10.1016/j.jpsychores.2025.112498","DOIUrl":"10.1016/j.jpsychores.2025.112498","url":null,"abstract":"<div><h3>Backgrounds</h3><div>Mobile-based lifestyle intervention has been widely used to improve behavior for obesity and overweight. This study targeting adults with metabolic abnormalities aims to identify neural correlates related to weight loss due to mobile-based lifestyle intervention.</div></div><div><h3>Methods</h3><div>We conducted 8 weeks of mobile-based lifestyle intervention for 37 adults with metabolic abnormalities, including overweight. Participants underwent physical measurements, blood tests, psychometric questionnaires, and resting-state functional magnetic resonance imaging (fMRI) scans before and after the mobile-based intervention. For the resting-state fMRI, brain regions that showed changes in functional connectivity (FC) before and after mobile-based intervention were explored. Seed-based FC analysis was performed focusing on the subregions of the insular cortex.</div></div><div><h3>Results</h3><div>Participants significantly reduced body mass index (BMI) after mobile-based intervention. The degree of BMI reduction was significantly correlated with compliance with the intervention. In resting fMRI, FC of the posterior insula with the bilateral inferior parietal lobule and the left ventrolateral prefrontal cortex were enhanced after mobile-based intervention. The increase in FC between the posterior insula and the inferior posterior lobule showed a significant correlation with the decrease in binge eating scale scores.</div></div><div><h3>Conclusion</h3><div>The mobile-based lifestyle intervention significantly reduced weight and alleviated binge eating in adults with metabolic abnormalities. FC enhancement between the posterior insula and the frontoparietal regions was also observed after mobile-based lifestyle intervention. The relationship between these FC changes and strengthening weight control through mobile-based lifestyle intervention should be investigated through future research.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"201 ","pages":"Article 112498"},"PeriodicalIF":3.3,"publicationDate":"2025-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145828992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biopsychosocial risk factors for the transition from acute to chronic back pain: A prospective cohort study 从急性到慢性背痛转变的生物心理社会风险因素:一项前瞻性队列研究。
IF 3.3 2区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-13 DOI: 10.1016/j.jpsychores.2025.112500
Petra Engelmann, Mareike Busmann, Bernd Löwe, Paul Hüsing

Background

Biopsychosocial mechanisms are assumed to underlie the chronification of back pain; however, potentially relevant factors have mainly been examined in isolation rather than within comprehensive aetiological models. This study investigated risk factors of chronic back pain based on a current biopsychosocial model for persistent somatic symptoms.

Methods

Within the prospective cohort study IDRIS (“From the identification of biopsychosocial risk factors to an increase in pain-related self-efficacy – The online-based conveyance of an explanatory model for chronic back pain”), German adults with (sub)acute back pain (< 12 weeks) completed online questionnaires on biopsychosocial variables at baseline, 1-month and 3-month follow-up. Possible predisposing and maintaining predictors of chronic back pain at 3 months were tested in linear regression models.

Findings

Between December 2022 and July 2024, 280 individuals from the general population with (sub)acute back pain (mean age 37.52 (SD 12.41) years; 65 % female) completed all assessments. Predictors of chronic back pain at 3 months were dysfunctional symptom expectations at 1-month follow-up (ß = 0.25, p < 0.001) and high baseline pain severity grades (highest grade: ß = 0.18, p < 0.01). Other postulated variables did not predict pain chronification.

Interpretation

This study supports the role of negative pain-related beliefs in the transition from acute to chronic back pain and suggests addressing dysfunctional symptom expectations in secondary prevention interventions to mitigate the risk of pain chronification. Future research should assess postulated predisposing factors for chronic back pain in clinical populations over longer timeframes to evaluate their long-term predictive value.

Funding

Stiftung Psychosomatik der Wirbelsäulenerkrankungen.
背景:生物心理社会机制被认为是背痛慢性化的基础;然而,潜在的相关因素主要是孤立的,而不是综合的病因学模型。本研究基于当前持续躯体症状的生物心理社会模型调查了慢性背痛的危险因素。方法:在前瞻性队列研究IDRIS(“从生物心理社会风险因素的识别到疼痛相关自我效能的增加——慢性背痛的在线解释模型”)中,患有(亚)急性背痛(< 12周)的德国成年人在基线、1个月和3个月的随访中完成了生物心理社会变量的在线问卷调查。在线性回归模型中检验3个月时慢性背痛的可能易感因素和维持因素。研究结果:在2022年12月至2024年7月期间,来自普通人群的280例(亚)急性背痛患者(平均年龄37.52岁(SD 12.41岁);(65%为女性)完成了所有评估。3个月时慢性背痛的预测因子是1个月随访时的功能失调症状预期(ß = 0.25, p)。解释:本研究支持疼痛相关的消极信念在从急性到慢性背痛转变中的作用,并建议在二级预防干预中解决功能失调症状预期,以减轻疼痛慢性化的风险。未来的研究应该在更长的时间框架内评估临床人群中慢性背痛的假定诱发因素,以评估其长期预测价值。资助:Stiftung Psychosomatik der Wirbelsäulenerkrankungen
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引用次数: 0
Biopsychosocial factors associated with distress in people with suspected postural orthostatic tachycardia syndrome (POTS): A longitudinal regression and correlation study 与疑似体位性心动过速综合征(POTS)患者痛苦相关的生物心理社会因素:一项纵向回归和相关研究。
IF 3.3 2区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-13 DOI: 10.1016/j.jpsychores.2025.112499
Iris Knoop , Annie S.K. Jones , Sam Norton , Nicholas Gall , Rona Moss-Morris

Purpose

Postural Orthostatic Tachycardia Syndrome (POTS) is a debilitating condition of the autonomic nervous system with no clear referral, diagnosis, and treatment pathways. Patients experience high levels of symptoms and moderate levels of distress. The purpose of this study was to explore biopsychosocial factors associated with distress in those under investigation for POTS, to identify potential targets for intervention.

Methods

A longitudinal, quantitative survey. Participants (n = 149) completed demographic, psychosocial, and symptom questionnaires prior to a diagnostic POTS clinic visit and 6 months follow-up (n = 98). Correlation and regression analyses were used to identify factors associated with distress at baseline (within one month before diagnostic hospital visit) and at 6 months follow up.

Results

At baseline, distress levels were moderate and greater symptom focusing, all-or-nothing and avoidance behaviours, threatening views of the illness, emotional reactivity, cardiac anxiety, POTS symptoms, number of specialists seen, lower social support, and younger age were significantly associated with higher levels of baseline distress. The baseline regression model including all demographic, clinical, and psychosocial factors explained 61.2 % of the variance in distress, with the psychosocial variables collectively explaining 55.6 % of this variance (F = 11.06, p < .001). There was no significant difference between distress levels at baseline and follow-up. Psychosocial variables explained 4.7 % of the variance (F = 0.76, p = .665) in changes in distress scores over 6 months. Baseline distress scores accounted for the vast majority of variance in distress at follow-up.

Conclusions

This study identified key novel psychosocial factors that were significantly associated with distress which could be potential targets for intervention. Additional factors such as younger age and a higher number of specialists seen were also associated with higher levels of distress, which merits attention when assessing patients' psychological wellbeing this patient group. Distress levels did not significantly change following the specialist consultation and investigation.
目的:体位性站立性心动过速综合征(POTS)是一种自主神经系统衰弱性疾病,没有明确的转诊、诊断和治疗途径。患者会经历严重的症状和中度的痛苦。本研究的目的是探讨在接受调查的POTS患者中与痛苦相关的生物心理社会因素,以确定潜在的干预目标。方法:纵向定量调查。参与者(n = 149)在诊断性POTS门诊访问和6个月随访前完成了人口统计学、社会心理和症状问卷调查(n = 98)。相关和回归分析用于确定基线(诊断性医院就诊前1个月内)和6个月随访时与焦虑相关的因素。结果:基线时,痛苦水平为中度,更严重的症状集中、全有或全无和回避行为、对疾病的威胁性看法、情绪反应、心脏焦虑、POTS症状、看过的专家数量、较低的社会支持和较年轻的年龄与较高的基线痛苦水平显著相关。基线回归模型包括所有人口统计学、临床和社会心理因素,解释了61.2%的痛苦方差,社会心理变量共同解释了55.6%的差异(F = 11.06, p)。结论:本研究确定了与痛苦显著相关的关键的新型社会心理因素,这些因素可能是干预的潜在目标。其他因素,如年轻和更多的专家也与更高程度的痛苦有关,这在评估患者的心理健康时值得注意。在专家咨询和调查后,痛苦程度没有显著变化。
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引用次数: 0
Preoperative sleep quality and anxiety as predictors of postoperative pain and recovery in Gynecologic oncology surgery: A prospective observational study 术前睡眠质量和焦虑作为妇科肿瘤手术术后疼痛和恢复的预测因素:一项前瞻性观察研究
IF 3.3 2区 医学 Q2 PSYCHIATRY Pub Date : 2025-12-11 DOI: 10.1016/j.jpsychores.2025.112496
Celal Akdemir , Suna Aşkın Turan , Mücahit Furkan Balcı , Süleyman Özen , Nefise Şeker , Denizhan Bayramoğlu , Zeynep Bayramoğlu , Muzaffer Sancı

Purpose

This study evaluated associations between preoperative sleep quality, anxiety, and short-term postoperative outcomes in patients undergoing gynecologic oncology surgery.

Methods

This prospective observational study included 72 women undergoing open gynecologic cancer surgery. Preoperative sleep quality and anxiety were assessed 24–48 h before surgery using the Pittsburgh Sleep Quality Index (PSQI) and the Beck Anxiety Inventory (BAI). Postoperative pain was measured using the Numerical Rating Scale (NRS) at 0, 4, 8, 12, and 24 h. Complications, rescue analgesia use, and length of stay were recorded.

Results

Poor sleep quality (%31.9) and clinically significant anxiety (%19.4) were both associated with higher mean postoperative pain scores (PSQI ≥5: 6.3 ± 1.2 vs 5.1 ± 1.3, p = 0.002; BAI ≥16: 6.5 ± 1.1 vs 5.2 ± 1.4, p = 0.001). In adjusted analyses, higher PSQI (β = 0.112, 95 % CI 0.039–0.185, p = 0.003) and higher BAI scores (β = 0.044, 95 % CI 0.023–0.065, p < 0.001) remained significantly associated with increased mean pain. Poor sleep quality was also linked to longer hospitalization (4 vs 3 days, p < 0.001) and higher complication rates (%52.2 vs %12.2, p < 0.001). Elevated anxiety was similarly associated with higher complication rates (%57.1 vs %17.2, p = 0.004) and more frequent rescue analgesia use (%64.3 vs %29.3, p = 0.014).

Conclusion

Preoperative sleep disturbances and anxiety are significantly associated with worse postoperative pain, higher complication rates, and prolonged recovery; routine screening and targeted interventions may therefore improve surgical outcomes.

Trial registration

The study was retrospectively registered at ClinicalTrials.gov (Identifier: NCT07036549) on June 24, 2025.
目的:本研究评估妇科肿瘤手术患者术前睡眠质量、焦虑和术后短期预后之间的关系。方法本前瞻性观察研究纳入72例接受开放性妇科肿瘤手术的妇女。术前24-48 h采用匹兹堡睡眠质量指数(PSQI)和贝克焦虑量表(BAI)评估睡眠质量和焦虑。术后0、4、8、12和24 h采用数值评定量表(NRS)测量疼痛。记录并发症、抢救镇痛使用情况和住院时间。结果spoor睡眠质量(%31.9)和临床显著焦虑(%19.4)均与较高的术后平均疼痛评分相关(PSQI≥5:6.3±1.2 vs 5.1±1.3,p = 0.002; BAI≥16:6.5±1.1 vs 5.2±1.4,p = 0.001)。在校正分析中,较高的PSQI (β = 0.112, 95% CI 0.039-0.185, p = 0.003)和较高的BAI评分(β = 0.044, 95% CI 0.023-0.065, p < 0.001)仍然与平均疼痛增加显著相关。睡眠质量差还与住院时间较长(4天对3天,p < 0.001)和并发症发生率较高(% 52.2%对% 12.2%,p < 0.001)有关。焦虑升高同样与更高的并发症发生率(%57.1 vs %17.2, p = 0.004)和更频繁的急救镇痛使用相关(%64.3 vs %29.3, p = 0.014)。结论术前睡眠障碍和焦虑与术后疼痛加重、并发症发生率高、恢复时间长有显著关系;因此,常规筛查和有针对性的干预可以改善手术结果。试验注册该研究于2025年6月24日在ClinicalTrials.gov(标识符:NCT07036549)上回顾性注册。
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引用次数: 0
期刊
Journal of Psychosomatic Research
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