Journal of Psychosomatic Research最新文献_第7页

Biopsychosocial risk factors for the transition from acute to chronic back pain: A prospective cohort study 从急性到慢性背痛转变的生物心理社会风险因素：一项前瞻性队列研究。

IF 3.3 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research

Pub Date : 2026-03-01 Epub Date: 2025-12-13 DOI: 10.1016/j.jpsychores.2025.112500

Petra Engelmann, Mareike Busmann, Bernd Löwe, Paul Hüsing

Background

Biopsychosocial mechanisms are assumed to underlie the chronification of back pain; however, potentially relevant factors have mainly been examined in isolation rather than within comprehensive aetiological models. This study investigated risk factors of chronic back pain based on a current biopsychosocial model for persistent somatic symptoms.

Methods

Within the prospective cohort study IDRIS (“From the identification of biopsychosocial risk factors to an increase in pain-related self-efficacy – The online-based conveyance of an explanatory model for chronic back pain”), German adults with (sub)acute back pain (< 12 weeks) completed online questionnaires on biopsychosocial variables at baseline, 1-month and 3-month follow-up. Possible predisposing and maintaining predictors of chronic back pain at 3 months were tested in linear regression models.

Findings

Between December 2022 and July 2024, 280 individuals from the general population with (sub)acute back pain (mean age 37.52 (SD 12.41) years; 65 % female) completed all assessments. Predictors of chronic back pain at 3 months were dysfunctional symptom expectations at 1-month follow-up (ß = 0.25, p < 0.001) and high baseline pain severity grades (highest grade: ß = 0.18, p < 0.01). Other postulated variables did not predict pain chronification.

Interpretation

This study supports the role of negative pain-related beliefs in the transition from acute to chronic back pain and suggests addressing dysfunctional symptom expectations in secondary prevention interventions to mitigate the risk of pain chronification. Future research should assess postulated predisposing factors for chronic back pain in clinical populations over longer timeframes to evaluate their long-term predictive value.

Funding

Stiftung Psychosomatik der Wirbelsäulenerkrankungen.

背景：生物心理社会机制被认为是背痛慢性化的基础；然而，潜在的相关因素主要是孤立的，而不是综合的病因学模型。本研究基于当前持续躯体症状的生物心理社会模型调查了慢性背痛的危险因素。方法：在前瞻性队列研究IDRIS（“从生物心理社会风险因素的识别到疼痛相关自我效能的增加——慢性背痛的在线解释模型”）中，患有（亚）急性背痛（< 12周）的德国成年人在基线、1个月和3个月的随访中完成了生物心理社会变量的在线问卷调查。在线性回归模型中检验3个月时慢性背痛的可能易感因素和维持因素。研究结果：在2022年12月至2024年7月期间，来自普通人群的280例（亚）急性背痛患者(平均年龄37.52岁（SD 12.41岁）；（65%为女性）完成了所有评估。3个月时慢性背痛的预测因子是1个月随访时的功能失调症状预期（ß = 0.25, p）。解释：本研究支持疼痛相关的消极信念在从急性到慢性背痛转变中的作用，并建议在二级预防干预中解决功能失调症状预期，以减轻疼痛慢性化的风险。未来的研究应该在更长的时间框架内评估临床人群中慢性背痛的假定诱发因素，以评估其长期预测价值。资助：Stiftung Psychosomatik der Wirbelsäulenerkrankungen

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引用次数: 0

Network analysis of fear of progression, anxiety, and depression in parents of children with malignant solid tumors: A cross-sectional study 恶性实体瘤患儿父母对进展、焦虑和抑郁的恐惧网络分析：一项横断面研究。

IF 3.3 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research

Pub Date : 2026-03-01 Epub Date: 2026-01-02 DOI: 10.1016/j.jpsychores.2025.112516

Yiming Gao , Xiaohe Lin, Xiaona Shen, Xiangyu Zhao, Di Zhao, Ping Li

Objective

Fear of progression (FoP), anxiety, and depression are common emotional distresses for parents of children with cancer, but yet these concerns often lack attention. This study explored the network connections between FoP, anxiety, and depression in parents of children with malignant solid tumors.

Methods

This study that included 447 parents of children with malignant solid tumors. All participants completed the Fear of Progression Questionnaire-parent version (FoP-Q-SF/PR), the 2-item Generalize Anxiety Disorder Scale (GAD-2) and the 2-item Patient Health Questionnaire (PHQ-2). We estimated two network models: regularized partial correlation network and Bayesian Directed Acyclic Graph (DAG).

Results

The regularized partial correlation network demonstrated a correlation between FoP, anxiety, and depressive symptoms, with a stronger association observed between anxiety and depression. The results of the Network Centrality Indicator showed that the top three symptoms in terms of expected impact (EI) were “fear of major treatment”, “life anxiety”, and “feeling tense, anxious, or eager”. The DAG showed that the symptoms of FoP activated each other, which in turn activated anxiety and depressive symptoms. In particular, “fear of major treatment” was at the top of the DAG and therefore has the highest predictive priority in the network.

Conclusion: “Fear of major treatment” was a core symptom in the regularized partial correlation network and an upstream symptom in the DAG. The findings suggest that strengthening health education, building confidence in overcoming the disease, and reinforcing positive coping may help to improve negative emotions in parents of children with malignant solid tumors.

目的：恐惧进展（FoP）、焦虑和抑郁是癌症儿童父母常见的情绪困扰，但这些担忧往往缺乏关注。本研究探讨了恶性实体瘤患儿家长的FoP、焦虑和抑郁之间的网络联系。方法：本研究纳入447例恶性实体瘤患儿家长。所有参与者均完成了进展恐惧问卷-家长版（FoP-Q-SF/PR）、2项广泛性焦虑障碍量表（GAD-2）和2项患者健康问卷（PHQ-2）。我们估计了两种网络模型：正则化部分相关网络和贝叶斯有向无环图（DAG）。结果：正则化的部分相关网络显示了FoP、焦虑和抑郁症状之间的相关性，其中焦虑和抑郁之间的相关性更强。网络中心性指标（Network Centrality Indicator）结果显示，预期影响（EI）前三名的症状分别是“害怕重大治疗”、“生活焦虑”和“感到紧张、焦虑或渴望”。DAG显示，FoP的症状相互激活，进而激活焦虑和抑郁症状。特别是，“对重大治疗的恐惧”位于DAG的顶部，因此在网络中具有最高的预测优先级。结论：“对重大治疗的恐惧”是正则化部分相关网络的核心症状，是DAG的上游症状。研究结果提示，加强健康教育，树立战胜疾病的信心，加强积极应对，可能有助于改善恶性实体瘤患儿家长的负面情绪。

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引用次数: 0

A cross sectional study of post-concussion symptoms following mild traumatic brain injury in an Asian population: Influence of negative mental states and somatic features 亚洲人群轻度外伤性脑损伤后脑震荡症状的横断面研究：消极精神状态和躯体特征的影响

IF 3.3 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research

Pub Date : 2026-03-01 Epub Date: 2025-12-26 DOI: 10.1016/j.jpsychores.2025.112492

Simon L. Collinson , Nicole Chen , Kathryn Ponniah , Ray Chua , Annette Chen , Ang Beng Ti

Objective

Persistent post-concussion symptoms resulting from a mild traumatic brain injury that typically last longer than three months may stem from a complex interaction of neurological and psychological factors, particularly negative mental states. Negative mental states including pessimism and depression are associated with post-concussion phenomena may be highly pertinent to Asian societies. The objective of this study was to examine the respective influences of culture specific psychological factors in the presentation of post-concussion symptoms.

Method

We examined the relationship between somatisation, depression and pessimism in 83 Asian mild traumatic brain injury (mTBI) outpatients and found depression levels, including cognitive/affective depression and somatic depression sub-factors, were significantly greater in patients with moderate or severe symptoms.

Results

Somatic depression was the best predictor of the severity of post-concussion symptoms especially in individuals who were more pessimistic.

Conclusion

The findings highlight negative mental states and cultural differences in the manifestation of post-concussion symptoms that should inform both clinical assessment and intervention for persistent PCS.

目的：轻度外伤性脑损伤引起的持续性脑震荡后症状通常持续3个月以上，可能是神经和心理因素复杂相互作用的结果，尤其是消极的精神状态。包括悲观和抑郁在内的消极精神状态与脑震荡后的现象有关，这可能与亚洲社会高度相关。本研究的目的是探讨文化特定心理因素在脑震荡后症状表现中的各自影响。方法：我们对83例亚洲轻度创伤性脑损伤（mTBI）门诊患者的躯体化、抑郁和悲观情绪之间的关系进行了研究，发现抑郁水平，包括认知/情感抑郁和躯体抑郁亚因素，在中度或重度症状患者中显著更高。结果：躯体抑郁是脑震荡后症状严重程度的最佳预测因子，特别是在悲观的个体中。结论：研究结果强调了消极的精神状态和文化差异在脑震荡后症状的表现，应为持续性PCS的临床评估和干预提供信息。

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引用次数: 0

Family emotional climate, depressive symptoms, and pain prevalence: Testing mediation pathways among midlife and older Black Americans 家庭情绪气候、抑郁症状和疼痛患病率：在中年和老年美国黑人中测试调解途径

IF 3.3 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research

Pub Date : 2026-03-01 Epub Date: 2025-12-31 DOI: 10.1016/j.jpsychores.2025.112509

Sarah B. Woods , Bhaskar Thakur , Staja Booker , Beatrice Wood , Patricia N.E. Roberson

Objective

Family relationship quality has been linked to pain outcomes, recently for aging Black adults, yet possible mechanisms of effect remain heretofore untested. Guided by the Biobehavioral Family Model, this study tested whether depressive symptoms mediate prospective associations between family emotional climate and pain prevalence, and whether associations are moderated by baseline chronic pain status.

Methods

We tested hypothesized associations among Black American participants of the nationally representative Midlife in the United States study (second [2004–2006] and third [2013–2015] waves) who reported on pain prevalence (N = 471; 65.2 % women; μ[age] = 50.45), using mediation and moderated mediation models.

Results

Greater family strain was linked to a greater likelihood of chronic pain 10 years later via greater depressive symptoms. Greater family support was associated with a decreased likelihood of chronic pain via decreased depressive symptoms. Baseline chronic pain status moderated this indirect effect via its moderation of the direct link between family support and depressive symptoms, such that this effect was significantly stronger for individuals reporting baseline chronic pain.

Conclusion

Depression is well-supported as a chronic pain antecedent. This study provides initial evidence it may also serve as a mutable mechanism linking family emotional climate to pain for aging Black Americans. Primary care-based assessments of family emotional climate to intervene on family strain while mitigating depressive symptoms which reflect chronic strain may be pain-protective. Interventions may also benefit from enhancing family support especially for patients experiencing chronic pain. Additional within-group, longitudinal research is needed to further support the tested mechanism.

目的家庭关系质量与疼痛结果有关，最近对老年黑人成年人来说，但可能的影响机制迄今尚未得到检验。在生物行为家庭模型的指导下，本研究测试了抑郁症状是否介导家庭情绪气候与疼痛患病率之间的前瞻性关联，以及这种关联是否被基线慢性疼痛状态所调节。方法采用中介和调节中介模型，对美国具有全国代表性的中年研究（第二波[2004-2006]和第三波[2013-2015]）中报告疼痛患病率的美国黑人参与者（N = 471, 65.2%为女性，年龄= 50.45）的假设关联进行检验。结果：家庭压力越大，10年后抑郁症状越严重，患慢性疼痛的可能性越大。更多的家庭支持通过减少抑郁症状而降低慢性疼痛的可能性。基线慢性疼痛状态通过调节家庭支持和抑郁症状之间的直接联系来调节这种间接影响，因此这种影响对报告基线慢性疼痛的个体显着更强。结论抑郁是慢性疼痛的前因。这项研究提供了初步证据，它也可能作为一种可变机制，将家庭情感气候与老年美国黑人的痛苦联系起来。以初级保健为基础的家庭情绪气候评估，干预家庭紧张，同时减轻反映慢性紧张的抑郁症状，可能具有疼痛保护作用。干预措施也可能受益于加强家庭支持，特别是对患有慢性疼痛的患者。需要进一步的组内纵向研究来进一步支持已测试的机制。

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引用次数: 0

EAPM 2026 Florence EAPM 2026佛罗伦萨

IF 3.3 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research

Pub Date : 2026-03-01 Epub Date: 2026-02-05 DOI: 10.1016/S0022-3999(26)00056-5

引用次数: 0

Postsystolic shortening as indicator of regional myocardial dysfunction in patients with bipolar disorder 收缩后缩短作为双相情感障碍患者局部心肌功能障碍的指标。

IF 3.3 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research

Pub Date : 2026-03-01 Epub Date: 2026-01-09 DOI: 10.1016/j.jpsychores.2026.112528

Cheng-Yi Hsiao , Tzu-Yu Hsu , Kevin Li-Chun Hsieh , Hsin-Yi Lai , Yen-Kuang Lin , Kuo-Hsuan Chung , Shang-Ying Tsai , Pao-Huan Chen

Background

Patients with bipolar disorder (BD) have a high risk of heart failure. Postsystolic shortening has been proposed as a novel indicator of early cardiac dysfunction. In this exploratory study, postsystolic shortening and its potential association with BD characteristics, cardiometabolic risk factors, and inflammatory markers were evaluated in young adults with BD and mentally healthy individuals.

Methods

This study included 77 and 72 individuals in BD and mentally healthy control groups aged ≤45 years, respectively. The participants underwent two-dimensional speckle-tracking echocardiography, with postsystolic shortening index values calculated from the strain curve by using the following equation: ((maximum strain in cardiac cycle − peak systolic strain)/maximum strain in cardiac cycle) × 100. Cardiometabolic risk factors and inflammatory markers were derived from standard examinations in the hospital.

Results

Postsystolic shortening index values for the myocardial regions supplied by the left anterior descending artery (LAD; Cohen's d = 0.22, p = 0.057), left circumflex artery (LCX; Cohen's d = 0.34, p = 0.017), and right coronary artery (Cohen's d = 0.30, p = 0.003) were greater in patients with BD than in mentally healthy individuals of a similar age. Correlation analysis revealed that cardiometabolic risk factors and inflammatory markers in the BD group were positively correlated with higher postsystolic shortening index values for the LAD and LCX regions.

Conclusion

Postsystolic shortening is a potential indicator of regional myocardial dysfunction in patients with BD. Future replication studies should verify the current findings and investigate the mechanisms underlying the observed associations in this study.

背景：双相情感障碍（BD）患者发生心力衰竭的风险很高。收缩后缩短已被提出作为早期心功能障碍的新指标。在这项探索性研究中，我们评估了年轻成年双相障碍患者和心理健康个体的收缩后缩短及其与双相障碍特征、心脏代谢危险因素和炎症标志物的潜在关联。方法：选取年龄≤45岁的双相障碍组77例，心理健康对照组72例。参与者进行二维斑点跟踪超声心动图，根据应变曲线计算收缩后缩短指数值，公式如下：（（心周期最大应变-收缩峰值应变）/心周期最大应变）× 100。心脏代谢危险因素和炎症标志物来源于医院的标准检查。结果：BD患者的左前降支（LAD, Cohen’s d = 0.22, p = 0.057）、左旋支（LCX, Cohen’s d = 0.34, p = 0.017）、右冠状动脉（Cohen’s d = 0.30, p = 0.003）供血心肌区收缩后缩短指数高于同龄心理健康者。相关分析显示，BD组心脏代谢危险因素和炎症标志物与LAD和LCX区域收缩后缩短指数值升高呈正相关。结论：收缩后缩短是BD患者局部心肌功能障碍的潜在指标。未来的重复性研究应验证当前的发现，并探讨本研究中观察到的相关机制。

{"title":"Postsystolic shortening as indicator of regional myocardial dysfunction in patients with bipolar disorder","authors":"Cheng-Yi Hsiao , Tzu-Yu Hsu , Kevin Li-Chun Hsieh , Hsin-Yi Lai , Yen-Kuang Lin , Kuo-Hsuan Chung , Shang-Ying Tsai , Pao-Huan Chen","doi":"10.1016/j.jpsychores.2026.112528","DOIUrl":"10.1016/j.jpsychores.2026.112528","url":null,"abstract":"<div><h3>Background</h3><div>Patients with bipolar disorder (BD) have a high risk of heart failure. Postsystolic shortening has been proposed as a novel indicator of early cardiac dysfunction. In this exploratory study, postsystolic shortening and its potential association with BD characteristics, cardiometabolic risk factors, and inflammatory markers were evaluated in young adults with BD and mentally healthy individuals.</div></div><div><h3>Methods</h3><div>This study included 77 and 72 individuals in BD and mentally healthy control groups aged ≤45 years, respectively. The participants underwent two-dimensional speckle-tracking echocardiography, with postsystolic shortening index values calculated from the strain curve by using the following equation: ((maximum strain in cardiac cycle − peak systolic strain)/maximum strain in cardiac cycle) × 100. Cardiometabolic risk factors and inflammatory markers were derived from standard examinations in the hospital.</div></div><div><h3>Results</h3><div>Postsystolic shortening index values for the myocardial regions supplied by the left anterior descending artery (LAD; Cohen's <em>d</em> = 0.22, <em>p</em> = 0.057), left circumflex artery (LCX; Cohen's <em>d</em> = 0.34, <em>p</em> = 0.017), and right coronary artery (Cohen's <em>d</em> = 0.30, <em>p</em> = 0.003) were greater in patients with BD than in mentally healthy individuals of a similar age. Correlation analysis revealed that cardiometabolic risk factors and inflammatory markers in the BD group were positively correlated with higher postsystolic shortening index values for the LAD and LCX regions.</div></div><div><h3>Conclusion</h3><div>Postsystolic shortening is a potential indicator of regional myocardial dysfunction in patients with BD. Future replication studies should verify the current findings and investigate the mechanisms underlying the observed associations in this study.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"202 ","pages":"Article 112528"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The interplay between benefit finding and quality of life in maintenance hemodialysis patients: A cross-sectional network analysis 维持性血液透析患者的获益发现与生活质量之间的相互作用：横断面网络分析

IF 3.3 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research

Pub Date : 2026-03-01 Epub Date: 2026-01-11 DOI: 10.1016/j.jpsychores.2026.112533

Shuang Zhou , Zhiwu Tian , Qin Wu , Fuzhen Li , Hongmei Tao , Meifang Mai , Meifen Zhang

Objective

Maintenance hemodialysis (MHD) patients experience significant impacts on their quality of life (QoL). Benefit finding (BF) may influence QoL, but the specific structural relationships between BF dimensions and QoL domains remain unclear. The aim of this study was to identify core components of BF and QoL networks and bridging pathways linking them in MHD patients.

Methods

A cross-sectional study was conducted among 290 MHD patients from a tertiary hospital in China (January–June 2021). BF was assessed using the 22-item Benefit Finding Scale, and QoL was measured with the KDQOL-36™. Network analysis was employed to construct the BF-QoL network, estimate node centrality (strength, closeness, betweenness), and identify bridge connections. Stability was assessed using bootstrap methods (1000 samples).

Results

The BF network identified Personal Growth (strength = 2.367) as the most central node. In the QoL network, Effects of Kidney Disease (strength = 0.558) was central. Between-network analysis revealed Acceptance and Mental Composite Score as critical bridge nodes (highest betweenness: 1.592 and 1.298, respectively). Significant edges connected Acceptance to Mental Composite Score (r = 0.134, P < 0.05) and Health Behaviors to Physical Composite Score (r = 0.119, P < 0.05). Network sparsity was 0.4. Centrality stability was robust (correlation-stability coefficient > 0.5 for strength/closeness).

Conclusion

BF and QoL form an interconnected network in MHD patients. Personal Growth and Effects of Kidney Disease are central to their respective constructs, while Acceptance and mental health bridge BF and QoL. Interventions targeting these core nodes may optimize multidimensional QoL outcomes.

目的探讨维持性血液透析（MHD）对患者生活质量的影响。效益发现（BF）可能影响生活质量，但BF维度与生活质量领域之间的具体结构关系尚不清楚。本研究的目的是确定MHD患者BF和QoL网络的核心组成部分以及连接它们的桥接通路。方法对国内某三级医院290例MHD患者（2021年1月- 6月）进行横断面研究。使用22项效益发现量表评估BF，使用KDQOL-36™测量生活质量。网络分析用于构建BF-QoL网络，估计节点的中心性（强度、紧密度、中间度），并识别桥梁连接。稳定性评估采用自举法（1000个样本）。结果BF网络以个人成长（强度= 2.367）为最中心节点。在生活质量网络中，肾脏疾病的影响（强度= 0.558）是中心。网络间分析显示，接受度和心理综合得分是关键的桥梁节点（最高的网络间度分别为1.592和1.298）。接受度与心理综合得分（r = 0.134, P < 0.05）、健康行为与身体综合得分（r = 0.119, P < 0.05）相关。网络稀疏度为0.4。中心性稳定性是稳健的（强度/接近度的相关稳定性系数>； 0.5）。结论MHD患者的生活质量与生活质量是一个相互联系的网络。个人成长和肾脏疾病的影响是各自结构的中心，而接受和心理健康是BF和QoL的桥梁。针对这些核心节点的干预措施可以优化多维生活质量结果。

{"title":"The interplay between benefit finding and quality of life in maintenance hemodialysis patients: A cross-sectional network analysis","authors":"Shuang Zhou , Zhiwu Tian , Qin Wu , Fuzhen Li , Hongmei Tao , Meifang Mai , Meifen Zhang","doi":"10.1016/j.jpsychores.2026.112533","DOIUrl":"10.1016/j.jpsychores.2026.112533","url":null,"abstract":"<div><h3>Objective</h3><div>Maintenance hemodialysis (MHD) patients experience significant impacts on their quality of life (QoL). Benefit finding (BF) may influence QoL, but the specific structural relationships between BF dimensions and QoL domains remain unclear. The aim of this study was to identify core components of BF and QoL networks and bridging pathways linking them in MHD patients.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted among 290 MHD patients from a tertiary hospital in China (January–June 2021). BF was assessed using the 22-item Benefit Finding Scale, and QoL was measured with the KDQOL-36™. Network analysis was employed to construct the BF-QoL network, estimate node centrality (strength, closeness, betweenness), and identify bridge connections. Stability was assessed using bootstrap methods (1000 samples).</div></div><div><h3>Results</h3><div>The BF network identified Personal Growth (strength = 2.367) as the most central node. In the QoL network, Effects of Kidney Disease (strength = 0.558) was central. Between-network analysis revealed Acceptance and Mental Composite Score as critical bridge nodes (highest betweenness: 1.592 and 1.298, respectively). Significant edges connected Acceptance to Mental Composite Score (<em>r</em> = 0.134, <em>P</em> < 0.05) and Health Behaviors to Physical Composite Score (<em>r</em> = 0.119, <em>P</em> < 0.05). Network sparsity was 0.4. Centrality stability was robust (correlation-stability coefficient > 0.5 for strength/closeness).</div></div><div><h3>Conclusion</h3><div>BF and QoL form an interconnected network in MHD patients. Personal Growth and Effects of Kidney Disease are central to their respective constructs, while Acceptance and mental health bridge BF and QoL. Interventions targeting these core nodes may optimize multidimensional QoL outcomes.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"202 ","pages":"Article 112533"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145978786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors for fatigue symptoms in the general population over 7 years: Findings from the Cooperative Health Research in the Region of Augsburg F4 and FF4 studies 7岁以上普通人群疲劳症状的危险因素：来自奥格斯堡地区合作卫生研究F4和FF4研究的结果

IF 3.3 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research

Pub Date : 2026-03-01 Epub Date: 2025-12-31 DOI: 10.1016/j.jpsychores.2025.112511

Seryan Atasoy , Heribert Sattel , Constanze Hausteiner-Wiehle , Ina-Maria Rückert-Eheberg , Birgit Linkohr , Margit Heier , Karl-Heinz Ladwig , Annette Peters , Peter Henningsen

Background

To examine sex-specific risk factors of elevated fatigue symptoms over 7 years in a large community cohort.

Methods

Data were drawn from 1700 adults (52.3 % women; mean age = 49.6 ± 9.4 years) participating in the KORA F4 study and its 7-year follow-up (FF4) in Augsburg, Germany. Fatigue symptoms (0−12) were assessed at both time points using four items from the Depression and Exhaustion Scale. Sex-stratified generalized estimating equation (GEE) models examined associations with sociodemographic, behavioural, medical (BMI, medical illness, hemoglobin, C-reactive protein, thyroid-stimulating hormone [TSH], Epstein–Barr virus), psychological (depression, anxiety, childhood trauma), and bodily distress factors (somatization, self-rated health, pain, sleep complaints).

Results

Women reported significantly higher fatigue levels than men at both assessments. Cross-sectionally, higher baseline fatigue was associated with physical inactivity, medical illness, and multiple psychological and bodily distress factors. Several associations differed descriptively by sex: psychological distress and medical utilization showed stronger links in women, whereas sociodemographic factors and selected biomarkers were more relevant in men. Longitudinally, fatigue levels were stable over the follow-up, with baseline fatigue emerging as the main predictor of subsequent fatigue (men: OR = 1.65[1.55–1.77]; women: OR = 1.72 [1.59–1.86]). Physical inactivity and somatization predicted fatigue in both sexes. Depression symptoms, childhood trauma, and lower TSH predicted fatigue only in women, whereas sleep complaints were uniquely predictive in men. Medical measures showed limited value.

Conclusion

Baseline fatigue was linked to behavioural, medical, and psychosocial risk profiles, while longitudinal analyses revealed distress and prior fatigue as the key predictors of elevated fatigue symptoms over time.

背景：在一个大型社区队列中研究7年来疲劳症状升高的性别特异性危险因素。方法数据来自德国奥格斯堡参加KORA F4研究及其7年随访（FF4）的1700名成年人（52.3%为女性，平均年龄= 49.6±9.4岁）。使用抑郁和疲惫量表中的四个项目在两个时间点评估疲劳症状（0 - 12）。性别分层广义估计方程（GEE）模型研究了与社会人口学、行为、医学（BMI、医学疾病、血红蛋白、c反应蛋白、促甲状腺激素[TSH]、eb病毒）、心理（抑郁、焦虑、童年创伤）和身体困扰因素（躯体化、自评健康、疼痛、睡眠抱怨）的关联。结果在两项评估中，女性报告的疲劳程度明显高于男性。横断面上，较高的基线疲劳与缺乏身体活动、医疗疾病以及多种心理和身体痛苦因素有关。一些关联在描述上因性别而异：心理困扰和医疗利用在女性中表现出更强的联系，而社会人口因素和选定的生物标志物在男性中更为相关。纵向上，疲劳水平在随访期间保持稳定，基线疲劳成为后续疲劳的主要预测因子（男性：OR = 1.65[1.55-1.77]；女性：OR = 1.72[1.59-1.86]）。缺乏运动和躯体化预示着男女都会感到疲劳。抑郁症状、童年创伤和较低的TSH仅在女性中预测疲劳，而睡眠抱怨在男性中是唯一的预测因素。医疗措施的作用有限。结论：基线疲劳与行为、医学和社会心理风险概况有关，而纵向分析显示，随着时间的推移，痛苦和先前的疲劳是疲劳症状加剧的关键预测因素。

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引用次数: 0

Emotional outcomes are poorer in adults with developmental coordination disorder: A systematic review and meta-analyses 成人发育性协调障碍患者的情绪结果较差：一项系统回顾和荟萃分析。

IF 3.3 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research

Pub Date : 2026-03-01 Epub Date: 2026-01-11 DOI: 10.1016/j.jpsychores.2026.112537

Jorge Lopes Cavalcante-Neto , Matthew Bourke , João Mateus Carneiro Silva , John Cairney

Background

Evidence of the relationship between emotional problems and developmental coordination disorder (DCD) in adulthood remains scarce. The aim was to conduct a systematic review and meta-analysis to compare emotional outcomes in adults with and without DCD, controlling for outcome type, age and method of DCD identification.

Methods

Emotional outcomes were categorised into five categories: (i) anxiety; (ii) depression; (iv) psychological domain of quality of life; (v) stress, and (vi) subjective wellbeing. The Newcastle-Ottawa Quality Assessment Scale (NOS) assessed study quality. Cluster robust variance meta-analyses estimated a pooled standardized mean difference in emotional problems between adults with and without DCD. Subgroup analyses determined if effect sizes differed between outcome types, age groups and the method of DCD identification.

Results

From 5025 retrieved articles, 12 met the inclusion criteria. From these articles, 1890 participants (1025 with DCD and 865 with TD), aged 18–66 years, were included in the meta-analysis. No studies were classified as high quality, though most were of moderate quality (8/12). Adults with DCD reported significantly more emotional symptoms (SMD = 0.79, 95%CI = 0.51, 1.07) than their peers. Large effects sizes were maintained after excluding low quality studies and controlling for age, outcomes, and DCD identification method.

Conclusion

This review highlights the burden of emotional outcomes problems in adults with DCD and may support the identification of the condition in adulthood, as high levels of anxiety, depression, and stress, along with low psychological quality of life and self-esteem, are key features associated with the condition in this population.

背景：成年期情绪问题与发育性协调障碍（DCD）之间关系的证据仍然很少。目的是进行系统回顾和荟萃分析，比较患有和不患有DCD的成年人的情绪结果，控制结果类型，年龄和DCD识别方法。方法：将情绪结局分为5类：(i)焦虑；(2)抑郁;生活质量的心理领域；(v)压力；（vi）主观幸福感。纽卡斯尔-渥太华质量评估量表（NOS）评估研究质量。聚类稳健性方差荟萃分析估计了有和没有DCD的成年人在情绪问题上的标准化平均差异。亚组分析确定结果类型、年龄组和DCD鉴定方法之间的效应大小是否不同。结果：在5025篇检索文章中，有12篇符合纳入标准。从这些文章中，1890名参与者（1025名DCD患者和865名TD患者），年龄在18-66岁，被纳入meta分析。没有研究被归类为高质量，尽管大多数是中等质量（8/12）。患有DCD的成年人报告的情绪症状明显多于同龄人（SMD = 0.79, 95%CI = 0.51, 1.07）。在排除低质量研究并控制年龄、结局和DCD识别方法后，仍保持较大的效应量。结论：本综述强调了成年DCD患者的情绪结局问题负担，并可能支持成年后对该疾病的识别，因为高水平的焦虑、抑郁和压力，以及低心理生活质量和自尊，是该人群中与该疾病相关的关键特征。

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引用次数: 0

A short report: The Danish model for organization of healthcare for functional somatic disorders in children and adolescents. 一份简短的报告：丹麦儿童和青少年功能性躯体疾病保健组织模式。

IF 3.3 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research

Pub Date : 2026-02-23 DOI: 10.1016/j.jpsychores.2026.112606

Charlotte Ulrikka Rask, Karen Hansen Kallesøe

Objective: To describe the development of a Danish national stepped-care model for children and adolescents with functional somatic disorders (FSD).

Methods: Model development was coordinated by the Danish Health Authority and informed by epidemiological findings from the Copenhagen Child Cohort 2000 (CCC2000), a national survey of pediatric services, the introduction of common diagnostic codes, and multidisciplinary expert collaboration. Organizational planning emphasized coherence across healthcare levels and integration of pediatric and child and adolescent psychiatric expertise.

Results: Drawing on this empirical and clinical foundation, a three-step model was established to align treatment intensity with symptom severity. Mild cases are managed in primary care through normalization of bodily sensations, reassurance, and activity-based guidance. Moderate cases are treated in pediatric departments with structured psychoeducation and a gradual return to daily activities supported by multi-agency network meetings. Severe and complex cases are jointly managed by pediatric and child and adolescent psychiatric teams, including specialized psychological therapies and family support. The national implementation strategy includes developing multidisciplinary teams in each region, whereas workforce education is organized by the Danish Medical Society for Functional Disorders.

Conclusion: The Danish model aims to deliver coordinated, and developmentally informed care for pediatric FSD through interdisciplinary collaboration and stepped intervention. Continued investment in implementation, evaluation, and workforce development will be essential.

目的：描述丹麦儿童和青少年功能性躯体障碍（FSD）国家阶梯护理模式的发展。方法：模型的开发由丹麦卫生当局协调，并参考哥本哈根儿童队列2000 （CCC2000）的流行病学调查结果、一项儿科服务全国调查、通用诊断代码的引入和多学科专家合作。组织规划强调卫生保健水平的一致性以及儿科、儿童和青少年精神病学专业知识的整合。结果：在此经验和临床基础上，建立了治疗强度与症状严重程度的三步模型。在初级保健中，通过身体感觉的正常化、安慰和以活动为基础的指导来处理轻度病例。中度病例在儿科进行有组织的心理教育，并在多机构网络会议的支持下逐渐恢复日常活动。严重和复杂的病例由儿科和儿童及青少年精神病小组联合管理，包括专门的心理治疗和家庭支持。国家实施战略包括在每个区域建立多学科小组，而劳动力教育则由丹麦功能障碍医学协会组织。结论：丹麦模式旨在通过跨学科合作和阶梯式干预，为儿童FSD提供协调和发育知情的护理。在实施、评估和劳动力发展方面的持续投资将是必不可少的。

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