Aim
Post-stroke sequelae, such as motor dysfunction, may reduce patients' participation in social activities, thereby increasing their risk of social isolation. Previous studies have linked fear of disease progression with social isolation, yet the underlying mechanisms of this association remain unclear. To develop effective intervention strategies, it is essential to explore the contributing factors related to social isolation in depth.
Methods
This study aimed to investigate the mediating roles of self-perceived burden and self-disclosure in the relationship between fear of disease progression and social isolation among stroke patients. A total of 342 inpatients from neurology departments were surveyed using a self-designed demographic questionnaire, the Generalized Alienation Scale (GAS), Fear of Progression Questionnaire-Short Form (FoP-Q-SF), Self-Perceived Burden Scale (SPBS), and Distress Disclosure Index (DDI). A parallel mediation model was constructed, and descriptive statistics, difference tests, Spearman correlation analysis, hierarchical multiple regression, and mediation effect analysis were conducted.
Results
Fear of disease progression was positively associated with social isolation (c = 0.275). It was positively related to self-perceived burden (a1 = 0.598) and negatively related to self-disclosure (a2 = −0.412). Both mediators were significantly associated with social isolation (b1 = 0.188; b2 = −0.099). Significant indirect effects were found through self-perceived burden (a1b1 = 0.113) and self-disclosure (a2b2 = 0.041). The direct effect remained significant (c' = 0.121), indicating partial mediation.
Conclusion
Self-perceived burden and self-disclosure simultaneously mediate the impact of fear of disease progression on social isolation, offering new insights for healthcare professionals aiming to prevent social isolation among stroke survivors.
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