Journal of Laparoendoscopic & Advanced Surgical Techniques最新文献

Background: Isolated splenic metastasis from malignant melanoma is exceedingly rare and is usually associated with disseminated disease.

Methods: A 68-year-old man with a history of stage IIB nodular melanoma of the scalp (Breslow thickness 4 mm), treated with wide excision, negative sentinel lymph node biopsy, and adjuvant immunotherapy, was found on routine surveillance positron emission tomography/computed tomography to have a solitary hypermetabolic splenic lesion (SUVmax 8.8). No other metastatic sites were identified.

Results: A laparoscopic splenectomy was performed without intraoperative or postoperative complications. Histopathological analysis confirmed metastatic melanoma. The patient recovered uneventfully and remains under oncological follow-up.

Conclusion: This case highlights the role of laparoscopic splenectomy as a safe and effective diagnostic and therapeutic approach for isolated splenic metastasis in selected melanoma patients.

Background: En bloc and R0 resection of nonpedunculated colonic lesions by conventional endoscopic mucosal resection (EMR) are challenging. Preliminary lesion molding-aided EMR (PM-EMR) is useful for reducing snaring slippage, which may increase successful en bloc and R0 resection rates. Herein, we compared PM-EMR and conventional EMR outcomes.

Methods: Overall, 112 patients with nonpedunculated colonic lesions measuring 8-15 mm were randomly allocated to either the PM-EMR group or the conventional EMR group. Baseline characteristics and treatment results were analyzed between the groups.

Results: En bloc resection and R0 resection were achieved in the PM-EMR group (100%, 94.6%) and the conventional EMR group (76.8%, 67.9%). For lesions ≥ 10 mm, en bloc and R0 resection rates were greater for PM-EMR than for conventional EMR (100.0% versus 74.4%; 94.4% versus 62.8%, respectively). For lesions with macroscopic morphologies indicating Is/IIa located in the left/right colon, PM-EMR was significantly better than conventional EMR for en bloc resection (100.0% versus 69.2%, 100% versus 76.5%; 100.0% versus 75.0%, 100.0% versus 68.2%, respectively) and R0 resection (100.0% versus 65.4%, 88.9% versus 52.9%; 100.0% versus 60.0%, 90.0% versus 63.6%, respectively).

Conclusions: PM-EMR is significantly better than conventional EMR regarding en bloc and R0 resection of 10-15 mm nonpedunculated colorectal lesions.

Background: Despite advancements, specimen extraction through mini-laparotomy in traditional minimally invasive surgery still carries risks of wound-related complications such as infection, incisional hernia, and poor cosmetic results. Natural orifice specimen extraction (NOSE) has been suggested as an alternative to eliminate the need for an abdominal incision, potentially improving postoperative recovery and reducing complications. This systematic review aims to critically compare the clinical and oncologic outcomes of NOSE with conventional laparoscopic anterior resection.

Methods: Our search was conducted in line with the most recent Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations. An electronic search was conducted of the PubMed and EMBASE databases up to March 2025.

Results: After screening, 14 studies including 1149 patients undergoing anterior resection of rectal, sigmoid, and rectosigmoid tumors were included in this review, comprising 502 NOSE and 647 conventional patients. Compared with conventional transabdominal specimen extraction, NOSE was associated with longer operative time (weighted mean difference [WMD]: 12.44 minutes; 95% CI: 1.54-23.35; P = .03), lower estimated blood loss (WMD: -13.75 mL; 95% CI: -25.33 to -2.16; P = .02), and shorter hospital stays (WMD: -0.75 days; 95% CI: -1.03 to -0.48; P < .001). The tumor diameter was smaller in the NOSE cohort (WMD: -0.43 cm; 95% CI: -0.73 to -0.14; P < .01), but there were no significant differences in total lymph node harvest or number of metastatic nodes compared with the conventional approach. Overall complication rates favored NOSE (OR: 0.54; 95% CI: 0.34-0.86; P = .01), driven largely by reduced infections (OR: 0.24; P = .003), while anastomotic leak, hemorrhage, ileus, and reoperation rates did not differ significantly.

Conclusions: NOSE is a potential alternative in select patients undergoing anterior resection. However, it is associated with longer operative times, and there is a lack of data on long-term outcomes, such as hernia formation or oncologic safety.

Background: Minimally invasive colorectal surgery (MIS) offers reduced pain, faster bowel recovery, and shorter hospitalization compared with open surgery. In patients requiring a stoma, the stoma site can be used for specimen extraction, reducing the number of incisions. However, stoma-related complications, particularly parastomal hernia, may be increased. We synthesized evidence comparing stoma-site specimen extraction (SSE) with alternative extraction sites in MIS.

Methods: A systematic review and meta-analyses were conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Searches of PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and gray literature were performed (1990-2025). Eligible studies included adults undergoing elective laparoscopic or robotic colorectal surgery with SSE compared against midline or other extraction sites. Outcomes included stoma-related and nonstoma complications, perioperative parameters, and oncologic safety. Random-effect models were applied. Risk of bias was assessed using a modified Newcastle-Ottawa Scale. The study was prospectively registered with PROSPERO (CRD420251137576).

Results: Eighteen studies comprising 5699 patients (SSE: 1363; midline: 539; other incisions: 3797) were included. Overall, stoma-related complication rates were comparable between groups (SSE versus midline: OR: 1.04, 95% confidence interval [CI]: 0.37-2.89; SSE versus others: OR: 1.13, 95% CI: 0.75-1.68). The risk of parastomal hernia did not differ significantly between SSE and comparators (SSE versus midline: OR: 2.67, 95% CI: 0.53-13.54; SSE versus others: OR: 1.36, 95% CI: 0.69-2.67). Non-stoma-related complications (OR: 0.96, 95% CI: 0.66-1.38) and readmission rates were also similar. Perioperative outcomes favored SSE, with shorter operative time (mean difference -22.6 minutes versus others) and earlier return of flatus.

Conclusions: SSE is a safe and effective technique in MIS, offering perioperative benefits without increasing overall complication rates. Although parastomal hernia incidence was not significantly higher, vigilance is required, particularly in patients with permanent stomas. With appropriate case selection and meticulous closure, SSE represents a technique of MIS that reduces abdominal wall trauma while maintaining surgical safety.

Background: There has been systematic review and meta analysis (SRMA) on comparison of hepaticoduodenostomy (HD) and hepaticojejunostomy (HJ) in choledochal cysts (CDC), which included both open and laparoscopic procedures. There is no SRMA, comparing them in pediatric CDC which were managed exclusively by laparoscopy.

Methods: Studies comparing laparoscopic HD and HJ after CDC excision were identified from Medline, Ovid, Google Scholar, and Cochrane library. Suitable studies were reviewed and meta-analyzed. Outcomes evaluated included operative time, hospital stay, and incidence of postoperative bile leak, cholangitis, reflux/gastritis, anastomotic stricture, bleeding, intestinal obstruction, and re-operative rate.

Results: Nine retrospective studies were included, comprising total of 1903 patients, 457 of whom (24%) underwent HD, and 1446 (76%) underwent HJ. There was higher incidence of cholangitis in HJ (3.05%) than in HD (1.55%), though the difference was not statistically significant (P = .54). Reflux gastritis in the HD was 8.83% while that from the HJ was 0.87%. Meta-analysis favored HJ (odds ratio [OR]: 20.38, 95% confidence interval [CI]: 4.24 to 97.94; P = .002). For the mean operative time, Pooled Mean difference (MD: -56.93; 95% CI: -66.11, -45.75; P = .00001) was significant favoring HD. Outcomes such as hospital stay, bile leak, anastomotic stricture, bleeding, reoperation rate, and adhesive obstruction were comparable.

Conclusion: Laparoscopic HD and HJ show comparable short-term safety after CDC excision, with no significant difference in bile leak or cholangitis. HD, however, carries a higher risk of bile reflux and gastritis, though the operative time is significantly shorter with HD, offering a technical advantage.

Purpose: Gastropexy during laparoscopic gastrostomy tube (GT) placement is commonly achieved using transfascial sutures (TFS), transabdominal sutures (TAS), or T-fasteners (TF). It is unknown whether the method of gastropexy influences the incidence of postoperative complications. We aimed to determine if the gastropexy approach impacts rates of common complications after laparoscopic GT placement.

Methods: A single-center retrospective review of children who underwent laparoscopic GT placement from January 2018 to May 2023 was conducted. Patients with concomitant procedures labeled wound class II (clean-contaminated) or greater were excluded. Primary outcomes included cellulitis, tube dislodgement, granulation tissue, emergency department visits, readmission, and reoperation. Comparisons were made between gastropexy approaches.

Results: A total of 332 patients were analyzed. One hundred seventy-nine children had TFS, 110 had TAS, and 43 had TF. Children with TF were older than other cohorts and more likely to have a GT placed for medication/fluid access. Patients with TAS placed less phone calls to the pediatric surgery clinic postoperatively compared to those with TFS or TF. All other complications were comparable between cohorts.

Conclusions: The gastropexy approach does not significantly impact rates of postoperative complications following laparoscopic GT placement in pediatric patients. The gastropexy approach may impact the number of postoperative phone calls, but the reasoning for this is unclear.

Aims: Robot-assisted laparoscopic pyeloplasty (RALP) pyeloplasty in infants with pelvi-ureteric junction obstruction (PUJO) poses distinct challenges due to limited working space, small anatomical structures, and the need to adapt adult robotic systems for pediatric use. This study presents surgical experience and highlights technical refinements that optimize the procedure and reduce complications.

Methods: A retrospective review was conducted of infants who underwent RALP between January 2023 and May 2025 using the da Vinci Xi system. Operative challenges were analyzed, and standardized strategies were implemented to improve exposure, minimize complications, and achieve precise anastomosis. Postoperative outcomes were assessed using renal ultrasonography and EC scans.

Results: Eleven male infants (mean age: 5.9 months; mean weight: 6.7 kg) underwent unilateral robotic dismembered pyeloplasty. All had antenatally detected hydronephrosis, with postnatal confirmation of PUJO (left: 6; right: 5). Presenting features included urinary tract infection (18.1%), palpable lump (45.4%), and asymptomatic cases (36.3%). Associated anomalies were noted in 45%-crossing vessels (n = 2), crossing vessel with malrotated kidney (n = 1), undescended testis (n = 1), and left renal agenesis (n = 1). All surgeries were completed robotically without conversion. Three robotic arms were used, omitting the assistant port. Mean operative time was 168 minutes, with a console time of 133.3 minutes. The average hospital stay was 4.4 days. Several technical refinements-preoperative bowel decompression, aspiration of the dilated renal pelvis, supraumbilical camera port placement, optimal port spacing, burping of trocars, and precise alignment of the remote center-were crucial in facilitating effective surgery within the restricted working space. No intraoperative complications were encountered. On follow-up (mean duration: 17.8 months), 90% of patients demonstrated improved drainage, while one required a redo pyeloplasty.

Conclusion: RALP in infants is a technically feasible, safe, and effective procedure when performed with appropriately tailored technical modifications and refinements.

Background: Postoperative leakage at the esophagogastric anastomosis is a well-recognized and significant complication following esophagectomy. In the past, treatment options were largely confined to either conservative, nonsurgical management or removal of the gastric conduit with construction of a cervical esophagostomy. Over the last decade, the development of endoluminal stents and endoscopic clipping techniques has provided a less invasive alternative, enabling effective closure of leaks without the need for further surgery and preserving the continuity of the reconstructed esophagus.

Methods: This report presents our initial clinical experiences with the combined use of stents and clips. It also reviews up-to-date evidence on patient selection, available stent designs, treatment success rates, procedure-related considerations, and the anticipated role of endoscopic approaches in managing postoperative esophagogastric anastomotic leakage.

Results: We report 3 cases who underwent endoscopic management for esophagogastric anastomotic leak with a combination of stent and clips. The success of the procedure was determined on the extent of the defect and source management, which frequently necessitated concurrent drainage and antibiotic therapy.

Conclusions: Conservative approaches have become increasingly significant in the treatment of anastomotic leaks following esophageal surgery. Our experience demonstrates that some challenging cases can be treated with a combination of endoscopic therapy methods.

Aim: This study aims to perform a comprehensive systematic review and meta-analysis to evaluate the impact of anticoagulation (AC) therapy on clinical outcomes during ventral hernia repair (VHR).

Materials and methods: A thorough online search was conducted using PubMed, Cochrane, and Embase databases. Studies comparing the use of AC therapy following VHR were included. The results analyzed were bleeding-related reoperation, hemorrhagic/thrombotic complications, length of stay, and transfusion rates. Statistical analysis was performed with Review Manager 5.4 using a random-effects model.

Results: From 1278 records, 4 studies were included, encompassing 41,868 patients (anticoagulants use = 4804; no AC = 32,649), with 25% on anticoagulant therapy submitted to minimally invasive surgery (MIS). Additionally, 90% of patients using anticoagulants underwent mesh placement. Overall analysis showed increased hemorrhagic/thrombotic complications (risk ratios [RR]: 2.3; 95% confidence interval [CI]: 1.13-4.8; P = .02), bleeding-related reoperation (RR: 6.5; 95% CI: 4.3-9.9; P < .00001), and longer hospital stays (mean difference: 1.69 days; 95% CI: .66 to 2.72 days; P = .001) in patients using anticoagulant medications. However, there was no increased risk of transfusion (RR: 2.14; 95% CI: 0.58-7.95; P = .26) between groups.

Conclusions: The use of anticoagulant therapy following VHR is associated with increased hemorrhagic/thrombotic complications, bleeding-related reoperations, prolonged hospitalization, and similar transfusion rates. Further research is still required to validate these findings and explore the impact of MIS on anticoagulated patients following VHR.

Large hepatic cysts can cause abdominal pain, pressure symptoms, or liver dysfunction. Although laparoscopic fenestration is the standard surgical approach, recurrence remains a concern. As laparoscopic hepatectomy techniques have advanced, we have adopted laparoscopic left lateral segmentectomy as a curative treatment for symptomatic cysts located in the left lateral segment. Between 2018 and 2023, 4 patients underwent laparoscopic left lateral segmentectomy for symptomatic hepatic cysts at our institution. All procedures were performed using five ports. Cystic fluid was aspirated as much as possible, and hepatic transection was conducted under the total Pringle maneuver using ultrasonic dissectors. Small vessels were sealed, while larger vessels and Glissonean pedicles were clipped or divided with linear staplers. Resected specimens were retrieved via an extended umbilical incision. Surgical and postoperative parameters were analyzed to evaluate the safety and efficacy of the procedure. The cohort included 1 male and 3 female patients, with a mean age of 63 years. Presenting symptoms included abdominal pressure (3 cases) and epigastric pain (1 case). The mean maximum cyst diameter was 16.3 cm, and the average aspirated volume was 950 mL. The mean operative time was 232 minutes, and the mean blood loss was 48 g. No postoperative complications were observed. The average postoperative hospital stay was 6 days. All patients experienced symptom resolution without delayed complications during follow-up. Laparoscopic left lateral segmentectomy might be a safe and curative surgical option for symptomatic hepatic cysts located in the left lateral segment.