Burns最新文献

{"title":"Long-term skin quality and scar formation after enzymatic debridement of deep-dermal burn wounds: A follow-up comparative study of Suprathel® and Jelonet®","authors":"Wolfram Heitzmann ,&nbsp;Mitja Mossing ,&nbsp;Maria von Kohout ,&nbsp;Yasser Alhujaili ,&nbsp;Jan Akkan ,&nbsp;Paul Christian Fuchs ,&nbsp;Rolf Lefering ,&nbsp;Jennifer Lynn Schiefer","doi":"10.1016/j.burns.2025.107803","DOIUrl":"10.1016/j.burns.2025.107803","url":null,"abstract":"<div><div>Recent advances in burn care have highlighted the benefits of enzymatic debridement in reducing long-term scarring by preserving viable dermal structures. Nexobrid®, a bromelain-based enzymatic debridement agent, has become an established treatment modality for deep-dermal burns, particularly of the hand, due to its selective action and tissue-sparing properties. After debridement, the choice of dressing critically influences inflammation, re-epithelialization, and ultimately scar quality and skin function. In clinical practice, Suprathel®, a synthetic copolymer membrane, and Jelonet®, a paraffin-impregnated gauze, are widely used. While Suprathel® offers improved pain control and patient comfort, Jelonet® remains a cost-effective standard.</div><div>Building on our previous intra-individual trial, which showed similar healing times but greater patient comfort with Suprathel®, this planned single-center, prospective long-term follow-up aims to address the lack of data on long-term scar quality and skin barrier function after enzymatic debridement. It includes the same 23 patients with deep-dermal hand burns who had received wound coverage with both Suprathel® and Jelonet® on comparable wound areas, assessed at 3, 6, and 12 months using objective instruments (Cutometer®, Mexameter®, Tewameter®, O2C®) and subjective scales (Vancouver Scar Scale, Patient and Observer Scar Assessment Scale).</div><div>Both dressings resulted in favorable and largely comparable scar outcomes over 12 months, with no significant differences in elasticity, perfusion, or overall clinical scar appearance. Subtle yet statistically significant differences in transepidermal water loss (p &lt; 0.01) and pigmentation (p &lt; 0.01) indicated a trend toward enhanced epidermal barrier restoration and reduced hypopigmentation in Suprathel®-treated areas, although these effects did not translate into perceptible clinical advantages.</div><div>These results confirm that both Suprathel® and Jelonet® are effective options for post-enzymatic debridement wound coverage, showing comparable long-term scar outcomes. The choice may reasonably depend on clinical workflow and dressing-management preferences, with Suprathel® remaining the standard in our burn center due to its reduced frequency of dressing changes.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107803"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145571730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning framework for bronchoscopic diagnosis of burn inhalation injury","authors":"Kaihe Zhang ,&nbsp;Suveer Singh","doi":"10.1016/j.burns.2025.107770","DOIUrl":"10.1016/j.burns.2025.107770","url":null,"abstract":"<div><div>Burn inhalation injury (BII) increases mortality and morbidity in burns patients. Accurate bronchoscopic grading, as the gold standard diagnostic modality, is important for prognostication and to optimize management. However, the most common currently used clinical grading system (abbreviated injury score, AIS) for BII, as a standardized grading method, uses manual judgement of visual features of the tracheobronchial mucosa. This is subjective and has limitations in classification accuracy, and reliability. A better, automated bronchoscopic grading system would have great clinical value. Hence, this study tested the predictive capability of a supervised deep learning technology-based rating method for bronchoscopically diagnosed BII. A pre-trained vision transformer model (ViT) was fine-tuned to automatically grade burn inhalation injury from clinical bronchoscopy recordings of 36 patients (1089 quality-controlled frames) at the London Burns centre. Labelled images were differentiated into training, validation, and test sets (70:20:10). The model was then applied to 2 tasks;1. Identification of the severity grade (modified simple system -none, mild, moderate, severe) and 2. Binary – presence or not of BII. Performance indicators (accuracy, precision, F1 and recall) were measured. Then, the ViT was developed further by transfer learning and data augmentation techniques, and predictive performance retested. Test sets of images in the trained model achieved 98.17 % accuracy, 98.15 % F1 score, 98.29 % precision and 98.17 % recall. For task 2, the enhanced model achieved an accuracy of 98.17 %, F1-score 98.21 %, precision 98.36 %, recall 98.17 %. Compared to traditional human visually graded scoring systems, and even other deep learning model-based studies, our method demonstrated a very promising predictive deep learning framework for application in grading inhalation injuries more accurately.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107770"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145617816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric testing of a French Canadian version of the MacHAND performance assessment short (MPA-SF) for the adult burn survivor population","authors":"Zoë Edger-Lacoursière ,&nbsp;Valérie Calva ,&nbsp;Noémie Germain ,&nbsp;Ingrid Malo Leclerc ,&nbsp;Elisabeth Marois-Pagé ,&nbsp;Geneviève Schneider ,&nbsp;Danielle Shashoua ,&nbsp;Chloé Tremblay ,&nbsp;Ariane Vaillancourt ,&nbsp;Jakub Sawicki ,&nbsp;Tara Packham ,&nbsp;José A. Correa ,&nbsp;Bernadette Nedelec","doi":"10.1016/j.burns.2025.107804","DOIUrl":"10.1016/j.burns.2025.107804","url":null,"abstract":"<div><div>Hand burns represent a frequent injury site, often leading to significant functional limitations. However, there is no systematically validated performance-based outcome (PerfO) assessment for burn survivors, making it difficult to plan, implement, and monitor interventions for hand function. The MacHAND performance assessment short (MPA-S) has recently been proposed as a quick, updated, and globally accessible tool for individuals with traumatic hand injuries and could be a suitable PerfO for hand burns, meriting evaluation. This study aimed to 1) translate the MPA-S and Sollerman Hand Function Test (SHFT) into French Canadian (MPA-SF and SHFT-F), and 2) evaluate the psychometric properties of the MPA-SF, including test-retest, inter-rater, and intra-rater reliability, as well as minimal detectable change with 95 % confidence (MDC95 %) and construct validity by examining its correlation with the French Canadian Burnt Hand Outcome Tool (BHOT-F) and SHFT-F. The secondary objective was to explore the relationship between the MPA-SF, SHFT-F, and BHOT-F scores with % total body surface area (TBSA) burned, presence of hand graft, and hand diagnoses. The translation process followed a standardized forwards-backwards method. Psychometric testing was conducted with 31 participants who sustained hand burns (50 hands). The MPA-SF exhibited excellent reliability and strong positive correlations with the SHFT-F; and weak to moderate negative correlations with the BHOT-F. The intra-rater MDC95 % was 0, and the inter-rater MDC95 % was 4.35 %. These findings suggest that the MPA-SF is a reliable tool for assessing hand function after burns, supporting its use in clinical practice and research. All instruction manuals and training videos are open-source.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107804"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145828963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: \"Adjunctive curcumin nano-micelles reduce overall pruritus intensity in refractory post-burn pruritus: A randomized controlled trial\"","authors":"Ying-Ming Ma ,&nbsp;Hui Sun ,&nbsp;Wei Shen ,&nbsp;Hua-Jie Zhong","doi":"10.1016/j.burns.2025.107769","DOIUrl":"10.1016/j.burns.2025.107769","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107769"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145617796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights from comparing blood perfusion metrics and Vancouver Scar Scale in keloid assessment","authors":"Junxian Wen ,&nbsp;Zhijin Li ,&nbsp;Shuo Li ,&nbsp;Lin Jin ,&nbsp;Huiying Gao ,&nbsp;Nanze Yu ,&nbsp;Xiaojun Wang","doi":"10.1016/j.burns.2025.107766","DOIUrl":"10.1016/j.burns.2025.107766","url":null,"abstract":"<div><div>Keloids are pathological scars characterized by excessive fibroproliferation that extend beyond the boundaries of the original wound. Their assessment and treatment remain challenging due to variability in severity and response to interventions. Current evaluation methods, such as the Vancouver Scar Scale (VSS), rely heavily on subjective observation, which can limit consistency and accuracy. Laser Speckle Contrast Imaging (LSCI) has emerged as an objective tool capable of evaluating keloid vascularity by assessing blood perfusion. This retrospective study analyzed 176 keloid lesions from 99 patients to explore the utility of LSCI in assessing keloid severity and monitoring treatment outcomes. Changes in blood perfusion (PU) ratios derived from LSCI (PU_{keloid/control}) before and after treatment were compared the corresponding pre- and post-treatment VSS scores. The results demonstrated a significant correlation between PU_{keloid/control} and VSS (ρ = 0.308, p &lt; 0.001), with linear regression showing an association between decreases in perfusion ratio and reductions in VSS (R² = 0.539, p &lt; 0.01). Clinical cases demonstrated that PU_{keloid/control} effectively identifies high-perfusion areas, guiding targeted interventions and improving treatment precision. The results suggest LSCI provides an objective, non-invasive method to assess keloid vascularity, complementing traditional tools to enhance scar evaluation and treatment planning.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107766"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145617729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microneedling accelerates burn wound healing and promotes collagen remodeling: Insights from a rodent model","authors":"Servet Elçin Alpat ,&nbsp;Burak Kaya ,&nbsp;Hilal Göktürk Nakkaş ,&nbsp;Pınar Bayram ,&nbsp;Şule Kızıl ,&nbsp;Belgin Can ,&nbsp;Serdar Mehmet Gültan","doi":"10.1016/j.burns.2025.107811","DOIUrl":"10.1016/j.burns.2025.107811","url":null,"abstract":"<div><h3>Objective</h3><div>Despite notable advancements in burn care, morbidity and mortality remain high, with progressive tissue loss typically occurring in the first 48 h post-injury. While microneedling and topical retinyl palmitate are recognized for their regenerative effects in dermatology, their roles in acute burn wound management are not well defined. This study aimed to evaluate the early therapeutic impact of microneedling and retinyl palmitate on burn wound progression in a standardized rat model.</div></div><div><h3>Materials and methods</h3><div>Twenty-four male Wistar albino rats were randomized into four groups (n = 6 each): untreated control, microneedling, microneedling plus retinyl palmitate, and retinyl palmitate alone. Under general anesthesia, a standardized comb burn injury was inflicted on the dorsal skin. Microneedling was performed once, 30 min after injury. Retinyl palmitate was applied topically once daily for 28 days. Wound healing progression was evaluated macroscopically by monitoring wound size and preservation of the zone of stasis. Histological assessment included H&amp;E, Masson’s Trichrome, PAS, Verhoeff–Van Gieson staining, and immunohistochemistry for collagen types I and III.</div></div><div><h3>Results</h3><div>Microneedling significantly reduced wound area and improved preservation of the stasis zone (p &lt; 0.05). Histologically, microneedling induced near-complete re-epithelialization, minimal inflammatory infiltration, and organized collagen type I deposition resembling normal skin architecture. Retinyl palmitate monotherapy failed to improve healing and was associated with persistent inflammation and delayed neovascularization. Combination therapy did not offer additional benefits.</div></div><div><h3>Conclusion</h3><div>Microneedling applied in the acute phase of burn injury accelerates healing, preserves viable tissue, and promotes favorable collagen remodeling. Retinyl palmitate showed no therapeutic benefit in this model. These findings highlight microneedling as a promising stand-alone intervention for early burn treatment and encourage clinical exploration of this technique in acute burn care.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107811"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on: \"Sleep disorder increases risk of psychiatric disorder in burn survivors\"","authors":"Ruiqing Fan","doi":"10.1016/j.burns.2025.107820","DOIUrl":"10.1016/j.burns.2025.107820","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107820"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Clinical study comparing full-thickness skin columns and split-thickness skin graft donor sites in terms of pain and healing outcomes\"","authors":"Qinyuan Wang,&nbsp;Chao Sun,&nbsp;Meihong Zhang","doi":"10.1016/j.burns.2025.107843","DOIUrl":"10.1016/j.burns.2025.107843","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107843"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145866173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ringer’s lactate alone or combined with isotonic sodium bicarbonate for burn resuscitation: Does acid–base correction translate into clinical benefit?","authors":"Thomas Langer","doi":"10.1016/j.burns.2025.107842","DOIUrl":"10.1016/j.burns.2025.107842","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107842"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145879199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: \"Use of selective decontamination of the digestive tract in burn patients – A European survey\"","authors":"Wenqi Lv,&nbsp;Xiaoyan Yan","doi":"10.1016/j.burns.2025.107809","DOIUrl":"10.1016/j.burns.2025.107809","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107809"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}