Burns最新文献

{"title":"Rehabilitation requirement after burns: An observational study of 436 pediatric patients in Chile","authors":"María Rojas-Goldsack ,&nbsp;Rolando Saavedra ,&nbsp;Karina Zalavari ,&nbsp;Johanna Díaz ,&nbsp;Francisca Besio ,&nbsp;Rodrigo Fuentes ,&nbsp;Orlando Flores","doi":"10.1016/j.burns.2025.107816","DOIUrl":"10.1016/j.burns.2025.107816","url":null,"abstract":"<div><h3>Background</h3><div>Burns are injuries that lead to sequelae requiring long-term treatment and rehabilitation. Despite their significance, there is limited research specifically addressing the need for rehabilitation in pediatric burn patients and the duration of such treatment.</div></div><div><h3>Objective</h3><div>To describe the demographic and clinical factors associated with rehabilitation needs in pediatric burn patients, and to report the duration of rehabilitation among those who required and received it.</div></div><div><h3>Methods</h3><div>A retrospective cohort study was conducted including all pediatric patients from a Chilean district who were admitted to a specialized outpatient burn center during 2011. The treatment received by these patients until December 31, 2024, was reviewed. Data were extracted from clinical records. We analyzed demographic, epidemiological, and clinical variables. To evaluate the risk of requiring rehabilitation, we calculated adjusted relative risks with 95 % confidence intervals.</div></div><div><h3>Results</h3><div>From 436 patients (median age at injury: 3.0 (IQR:6.0–1.0) years) admitted in 2011 from burn injuries, 20.9 % required rehabilitation, and 30.8 % of them received rehabilitation treatment for more than a year. Intermediate (RR 10.13; 95 % CI: 3.51–29.26) and deep burns (RR 23.03 95 % CI 6.95–76.29), as well as re-epithelialization time exceeding 15 days (RR 1.03 95 % CI 1.00–1.05), were significantly associated with rehabilitation need. The median rehabilitation duration was 0.18 years (95 % CI: 0.04–0.29).</div></div><div><h3>Conclusions</h3><div>A significant proportion of pediatric burn patients require rehabilitation, often lasting more than one year. Deep burn depth is the strongest predictor of the need for rehabilitation. Rehabilitation duration may vary from a few days to several years. Further research is warranted to elucidate the variables affecting rehabilitation duration.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107816"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on: “Red blood cell transfusion risk factors and outcomes in burn patients: A retrospective cohort study”","authors":"Liying Jin,&nbsp;Xingyi Yang","doi":"10.1016/j.burns.2025.107814","DOIUrl":"10.1016/j.burns.2025.107814","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107814"},"PeriodicalIF":2.9,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and care of burns in rural Rwanda: A prospective cohort study","authors":"Rachel Nzungize ,&nbsp;Cameron Gibson ,&nbsp;Eléazar Ndabarora ,&nbsp;Bernard Umutoniwase ,&nbsp;Ronald Tubasiime","doi":"10.1016/j.burns.2025.107815","DOIUrl":"10.1016/j.burns.2025.107815","url":null,"abstract":"<div><h3>Introduction</h3><div>Burns are the fourth most common type of injury presenting to emergency departments in Rwanda; however, research related to the epidemiology of burn injuries is limited. The objectives of this study were to investigate the epidemiology and treatment of burns in a rural region of Rwanda to better inform local public health initiatives.</div></div><div><h3>Methods</h3><div>Data collection took place at Kibogora Level Two Teaching Hospital in the Western Province of Rwanda from July 2023 to November 2024. Patients enrolled in the study included all burn patients who presented to the hospital during the study period. Data were collected through patient interviews and electronic medical records using a standardized form.</div></div><div><h3>Results</h3><div>Eighty burn patients presented to the hospital during the study period. Children most often presented with burn injuries, with 70 % (n = 56) of the study population being 0–15 years old. Scald was the most common type of burn (n = 60, 75 %). Burns were mostly related to cooking activities (n = 60, 75 %). Traditional medicine was used as first aid in 57.5 % (n = 46) of the cases. Time from injury to treatment was &gt; 24 h in 32.5 % (n = 26) of the patients. Complications were common at 43.8 % (n = 35), with the most frequent type being burn wound infection (n = 30, 37.5 %). All patients survived their burn injuries.</div></div><div><h3>Conclusion</h3><div>Prevention efforts should prioritize reaching children and their caregivers while highlighting kitchen safety and the dangers of hot liquids that can cause scald burn injuries. Burn wound infection prevention is also a priority for education.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107815"},"PeriodicalIF":2.9,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on: “Effect of Acceptance and Commitment Therapy on psychological wellbeing and physical function in rehabilitation patients after burns: A randomized controlled trial”","authors":"Danni Huang,&nbsp;Linping Zhu","doi":"10.1016/j.burns.2025.107812","DOIUrl":"10.1016/j.burns.2025.107812","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107812"},"PeriodicalIF":2.9,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with prolonged mechanical ventilation in the burn patient","authors":"Sofía Kohn,&nbsp;Alejandra Stolovas,&nbsp;Florencia Urrestarazu,&nbsp;Eliana Robatto,&nbsp;Juan Silva,&nbsp;Ignacio Aramendi","doi":"10.1016/j.burns.2025.107813","DOIUrl":"10.1016/j.burns.2025.107813","url":null,"abstract":"<div><h3>Introduction</h3><div>We evaluated the incidence of short-term mechanical ventilation (STMV) in patients admitted to our national burn centre (CENAQUE) and clinical findings (CF) associated with prolonged mechanical ventilation (PMV).</div></div><div><h3>Methods</h3><div>Retrospective review of all burn adults admitted to CENAQUE with endotracheal intubation (EI) between 2010 and 2023. Data included demographics, injury characteristics, and CF at intubation. Patients were categorised as ≤ 2 days ventilation (STMV) or &gt; 2 days (PMV). Multivariable logistic regression analysed associations between CF and PMV. Sensitivity (SE), specificity (SP), positive predictive value (PPV), and negative predictive value (NPV) were calculated for each CF.</div></div><div><h3>Results</h3><div>Among 973 patients, STMV incidence was 42.3 % (n = 412). PMV was significantly associated with total body surface area burn (TBSA) (OR 1.094; 1.076–1.113; p &lt; 0.001), age (OR 1.031; 1.022–1.040; p &lt; 0.001), full-thickness facial burn (FTFB) (OR 2.152; 1.131–4.096; p = 0.020), shock (OR 10.662; 3.623–31.375; p &lt; 0.001), and oral oedema (OR 0.590; 0.368–0.944; p = 0.028). Shock (SE 21.2 %, SP 99.0 %) and FTFB (SE 24.6 %, SP 95.4 %) were the most sensitive and specific CF for detecting PMV, with high PPV (96.7 % and 87.8 %) but low NPV (48.1 % and 48.3 %), respectively. In patients with TBSA &lt; 20 %, NPV increased to 60.6 % for shock and 61.2 % for FTFB.</div></div><div><h3>Conclusions</h3><div>STMV for prophylactic reasons is frequent in burn patients in our country and may represent potentially unnecessary intubations. PMV was associated with higher TBSA, age, FTFB, and shock. FTFB and shock showed the best overall diagnostic performance for detecting PMV, with moderate NPV in patients with TBSA &lt; 20 %. New protocols should be established in our region for airway management of burn patients.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107813"},"PeriodicalIF":2.9,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric testing of a French Canadian version of the MacHAND performance assessment short (MPA-SF) for the adult burn survivor population","authors":"Zoë Edger-Lacoursière ,&nbsp;Valérie Calva ,&nbsp;Noémie Germain ,&nbsp;Ingrid Malo Leclerc ,&nbsp;Elisabeth Marois-Pagé ,&nbsp;Geneviève Schneider ,&nbsp;Danielle Shashoua ,&nbsp;Chloé Tremblay ,&nbsp;Ariane Vaillancourt ,&nbsp;Jakub Sawicki ,&nbsp;Tara Packham ,&nbsp;José A. Correa ,&nbsp;Bernadette Nedelec","doi":"10.1016/j.burns.2025.107804","DOIUrl":"10.1016/j.burns.2025.107804","url":null,"abstract":"<div><div>Hand burns represent a frequent injury site, often leading to significant functional limitations. However, there is no systematically validated performance-based outcome (PerfO) assessment for burn survivors, making it difficult to plan, implement, and monitor interventions for hand function. The MacHAND performance assessment short (MPA-S) has recently been proposed as a quick, updated, and globally accessible tool for individuals with traumatic hand injuries and could be a suitable PerfO for hand burns, meriting evaluation. This study aimed to 1) translate the MPA-S and Sollerman Hand Function Test (SHFT) into French Canadian (MPA-SF and SHFT-F), and 2) evaluate the psychometric properties of the MPA-SF, including test-retest, inter-rater, and intra-rater reliability, as well as minimal detectable change with 95 % confidence (MDC95 %) and construct validity by examining its correlation with the French Canadian Burnt Hand Outcome Tool (BHOT-F) and SHFT-F. The secondary objective was to explore the relationship between the MPA-SF, SHFT-F, and BHOT-F scores with % total body surface area (TBSA) burned, presence of hand graft, and hand diagnoses. The translation process followed a standardized forwards-backwards method. Psychometric testing was conducted with 31 participants who sustained hand burns (50 hands). The MPA-SF exhibited excellent reliability and strong positive correlations with the SHFT-F; and weak to moderate negative correlations with the BHOT-F. The intra-rater MDC95 % was 0, and the inter-rater MDC95 % was 4.35 %. These findings suggest that the MPA-SF is a reliable tool for assessing hand function after burns, supporting its use in clinical practice and research. All instruction manuals and training videos are open-source.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107804"},"PeriodicalIF":2.9,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145828963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on: \"Establishing new education standards in burns – A scoping review\"","authors":"M. Vijayasimha ,&nbsp;Rajesh Prasad Jayaswal","doi":"10.1016/j.burns.2025.107810","DOIUrl":"10.1016/j.burns.2025.107810","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107810"},"PeriodicalIF":2.9,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: \"Use of selective decontamination of the digestive tract in burn patients – A European survey\"","authors":"Wenqi Lv,&nbsp;Xiaoyan Yan","doi":"10.1016/j.burns.2025.107809","DOIUrl":"10.1016/j.burns.2025.107809","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107809"},"PeriodicalIF":2.9,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effect of post-burn pruritus on patients' quality of life and experiences","authors":"Handan Aktas ,&nbsp;Zahide Tuncbilek ,&nbsp;Seyhan Hidiroğlu","doi":"10.1016/j.burns.2025.107808","DOIUrl":"10.1016/j.burns.2025.107808","url":null,"abstract":"<div><h3>Objective</h3><div>The study aims to determine the experiences of patients who suffer from post-burn pruritus and to evaluate the effect of pruritus on their quality of life.</div></div><div><h3>Method</h3><div>The research employed a mixed-methods approach, combining both quantitative and qualitative methods. The study was carried out at the burn center of a city hospital in Istanbul. Individuals aged 18 and over who suffered burns after April 15, 2019, and continued to experience pruritus complaints were included in the study. A total of 120 patients were included in the quantitative phase of the study. Data for the quantitative phase were collected using the Patient Information Form, the Pruritus Information Collection Form, the 12-Item Pruritus Severity Scale, and the Burn-Specific Health Scale between July 2019 and March 2020. The qualitative phase was conducted between August 2019 and February 2020, concurrently with the collection of quantitative data. In the qualitative phase, in-depth face-to-face interviews were carried out with 11 individuals using a Semi-Structured Interview Form.</div></div><div><h3>Results</h3><div>It was determined that the patients experienced pruritus ranging from mild to severe (3.00–19.00), with the average pruritus score indicating moderate severity (8.91 ± 3.90). Significant differences were found between groups in terms of pruritus severity based on length of hospital stay, depth of burn, total body surface area burned, burned body region, and the presence of grafts (p &lt; 0.05). In the in-depth interviews, it was found that burn patients struggled to cope with pruritus, that pruritus had an impact on their daily and family lives, and that it had physical, social, and psychological effects. Additionally, patients reported experiences related to the treatment of pruritus.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that as the severity, distribution, and persistence of pruritus increased, it was perceived by patients as an unbearable symptom; and that pruritus is a significant factor reducing the quality of life in burn patients. It is suggested that the proper evaluation of pruritus using objective measurement tools, the development of appropriate protocols for the treatment and follow-up of post-burn pruritus, and providing education and counseling services to help burn patients cope with pruritus could improve the quality of life for burn patients experiencing pruritus.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107808"},"PeriodicalIF":2.9,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BACH1 is stabilized by vitamin E and attenuates the formation of hypertrophic scar through the Wnt/β-catenin pathway","authors":"Wenkang Luan ,&nbsp;Shujun Fan ,&nbsp;Hanyi Jiang ,&nbsp;Dongwen Jiang ,&nbsp;Jinxiu Yang ,&nbsp;Leren He","doi":"10.1016/j.burns.2025.107807","DOIUrl":"10.1016/j.burns.2025.107807","url":null,"abstract":"<div><div>The molecular drivers behind the pathogenesis of hypertrophic scar (HS) formation have not been determined in a comprehensive manner. Aside from that, no consensus has been reached on the role of vitamin E in HS. For this reason, we have probed the causal effect of 2940 plasma proteins and 187 diets on HS through Mendelian randomization (MR). Colocalization analysis, summary-data-based MR (SMR), heterogeneity in dependent instruments (HEIDI), and MR phenome-wide association study (MR-PheWAS) were employed to identify the potential drug targets of HS. Human Protein Atlas, differential expression analysis, weighted co-expression network analysis (WGCNA) and single-cell analysis were utilized to confirm the key biomolecules in HS. To investigate the roles of critical molecules, we harvested primary fibroblasts and conducted validations using both in vitro and in vivo animal models. We put forth a viewpoint that the transcription factor BACH1 is causally related to the onset of HS, is a protective factor for HS, and may serve as its therapeutic target. We further determined that BACH1 reveals substantial expression in human skin tissue. BACH1 is under-expressed in HS tissues and fibroblasts. We confirmed that BACH1 and vitamin E act in an anti-scar role in primary fibroblasts and animal models through the Wnt/β-catenin pathway. Overall, our results demonstrate that BACH1 has an inhibitory effect on HS, and vitamin E attenuates the formation of HS by stabilizing BACH1.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107807"},"PeriodicalIF":2.9,"publicationDate":"2025-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}