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Age Differences in Experiences of Pandemic-Related Health and Economic Challenges Among Adults Aged 55 and Older. 55 岁及以上成年人对与大流行病相关的健康和经济挑战的体验存在年龄差异。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-06-01 DOI: 10.1093/geront/gnae023
Emily E Wiemers, I-Fen Lin, Anna Wiersma Strauss, Janecca Chin, V Joseph Hotz, Judith A Seltzer

Background and objectives: The oldest adults faced the highest risk of death and hospitalization from coronavirus disease 2019 (COVID-19), but less is known about whether they also were the most likely to experience pandemic-related economic, healthcare, and mental health challenges. Guided by prior research on vulnerability versus resilience among older adults, the current study investigated age differences in economic hardship, delays in medical care, and mental health outcomes among adults aged 55 and older.

Research design and methods: Data were from the COVID-19 module and Leave Behind Questionnaire in the 2020 Health and Retirement Study (HRS). We estimated linear probability models to examine differences in experiences of pandemic-related economic and health challenges by age group (55-64, 65-74, 75+) with and without controls for preexisting sociodemographic, social program, health, and economic characteristics from the 2018 HRS. Models accounting for differential mortality also were estimated.

Results: Adults aged 65-74 and 75+ experienced fewer economic and mental health challenges and those aged 75+ were less likely to delay medical care than adults aged 55-64. Age gradients were consistent across a broad range of measures and were robust to including controls. For all age groups, economic challenges were less common than delays in medical care or experiences of loneliness, stress, or being emotionally overwhelmed.

Discussion and implications: Even though the oldest adults were at the greatest risk of death and hospitalization from COVID-19, they experienced fewer secondary pandemic-related challenges. Future research should continue to explore the sources of this resilience for older adults.

背景和目标:最年长的成年人面临 COVID-19 的最高死亡和住院风险,但他们是否也最有可能经历与流行病相关的经济、医疗保健和心理健康挑战,人们对此知之甚少。本研究以先前关于老年人脆弱性与复原力的研究为指导,调查了 55 岁及以上成年人在经济困难、医疗延误和心理健康结果方面的年龄差异:数据来自 2020 年健康与退休研究(HRS)中的 COVID-19 模块和遗留问题问卷。我们估算了线性概率模型,以研究不同年龄组(55-64 岁、65-74 岁、75 岁以上)的人在经历与大流行相关的经济和健康挑战方面的差异,并对 2018 年 HRS 中已有的社会人口、社会项目、健康和经济特征进行了控制和未进行控制。还估算了考虑不同死亡率的模型:与 55-64 岁的成年人相比,65-74 岁和 75 岁以上的成年人经历的经济和心理健康挑战较少,75 岁以上的成年人推迟就医的可能性较小。年龄梯度在广泛的衡量标准中都是一致的,并且在纳入对照组后也是稳健的。在所有年龄组中,经济挑战的发生率低于医疗延误或孤独、压力或情绪失控的发生率:尽管最年长的成年人因 COVID-19 死亡和住院的风险最大,但他们经历的与大流行相关的次要挑战较少。未来的研究应继续探索老年人这种复原力的来源。
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引用次数: 0
Exploring Social Determinants of Mental Health of Older Unforced Migrants: A Systematic Review. 探索老年非强迫移民心理健康的社会决定因素:系统综述。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-06-01 DOI: 10.1093/geront/gnae003
Pankhuri Bhatia, Helen McLaren, Yunong Huang

Background and objectives: Although the vulnerabilities stemming from the intersection of aging and migration are widely recognized, the migration contexts and the factors influencing the mental health of older unforced migrants have received scant attention. This review explores the drivers of unforced migrations in later life and the individual, relational, and structural factors influencing their mental health and well-being.

Research design and methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a systematic search of 7 databases for English peer-reviewed journal articles was conducted. A total of 21 studies were identified and analyzed inductively.

Results: The review classified motivations for migration as push factors and pull factors: push factors such as escaping structural inequities in the homeland and pull factors included seeking better lifestyle opportunities and reuniting with family. The positive determinants of mental health included cordial family relationships, paid employment, the presence of a partner, and strong support networks. Advanced age, absence of a partner, lifestyle changes, lack of intergenerational support, poor language proficiency, unfavorable policies, lack of access to resources, and systemic biases negatively affected the mental health of older unforced migrants.

Discussion and implications: The review highlights the need to recognize the diversity among older migrants to develop policies and programs that address their specific circumstances. Recognizing their strengths, rather than focusing solely on their vulnerabilities will help create a more positive and supportive environment, enabling them to thrive in their new communities.

背景和目标:尽管人们普遍认识到老龄化和移民问题交织在一起所产生的脆弱性,但移民背景和影响老年非强迫移民心理健康的因素却很少受到关注。本综述探讨了晚年非被迫移民的驱动因素,以及影响其心理健康和福祉的个人、关系和结构性因素:研究设计与方法:根据 PRISMA 指南,对七个数据库中的英文同行评审期刊论文进行了系统检索。共确定了 21 项研究,并对其进行了归纳分析:综述将移民动机分为推动因素和拉动因素:推动因素包括逃离家乡的结构性不平等,拉动因素包括寻求更好的生活方式和与家人团聚。心理健康的积极决定因素包括融洽的家庭关系、有偿就业、有伴侣和强大的支持网络。高龄、没有伴侣、生活方式改变、缺乏代际支持、语言能力差、不利的政策、缺乏获得资源的机会以及系统性偏见对老年非强迫移民的心理健康产生了负面影响:本综述强调了认识老年移民多样性的必要性,以便针对他们的具体情况制定政策和计划。认识到他们的长处,而不是只关注他们的弱点,将有助于创造一个更加积极和有利的环境,使他们能够在新社区中茁壮成长。
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引用次数: 0
Unrelenting Growth and Diversification: Using the Health and Retirement Study to Illuminate Cannabis Use Among Aging Americans. 持续增长和多样化:利用健康与退休研究揭示美国老年人使用大麻的情况。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-06-01 DOI: 10.1093/geront/gnae016
Brian Kaskie, Divya Bhagianadh, Julie Bobitt, Fadi Martinos, Gary Milavetz, Kanika Arora

Background and objectives: Cannabis use among aging Americans continues to increase. We examine correlates of cannabis use including attitudes, state of residence, health status, and service use.

Research design and methods: Using the 2018 Health and Retirement Study Cannabis module completed by 1,372 respondents aged 50 and older, we distinguished current cannabis users from those who have never used or have some prior use. We linked 2018 and 2016 core HRS data and used multinomial regressions to identify associations among current use, attitudes, place of residence, as well as current (2018) and past (2016) medical conditions, pain, and sleep issues. We also examined associations among cannabis use, hospital stays, and outpatient medical visits.

Results: Past-year cannabis use reached 10.3% among aging Americans. Attitudes toward cannabis have changed over time with 4 of 5 survey respondents currently holding a favorable attitude. Attitude and state of residence were associated with current use. Cannabis users reported higher levels of pain, were more likely to use prescription opioids, and report activity limitations in both 2016 and 2018. Associations between cannabis use and sleep issues or concurrent healthcare use were not observed.

Discussion and implications: Changing attitudes and state legalization appear important for late middle-aged and older persons, and as many as 1 of every 5 persons over 50 may be using cannabis by 2030. Cannabis use among aging Americans warrants increased attention from care providers, program administrators, and policymakers, especially as a prevention or harm reduction strategy relative to prescription opioids.

背景和目的:美国老年人使用大麻的人数持续增加。我们研究了大麻使用的相关因素,包括态度、居住州、健康状况和服务使用情况:利用 1,372 名 50 岁及以上受访者完成的 2018 年健康与退休研究大麻模块,我们将目前的大麻使用者与从未使用过或以前使用过一些大麻的人区分开来。我们将 2018 年和 2016 年的核心 HRS 数据联系起来,并使用多项式回归来确定当前使用情况、态度、居住地以及当前(2018 年)和过去(2016 年)医疗状况、疼痛和睡眠问题之间的关联。我们还研究了大麻使用、住院和门诊就医之间的关联:上一年美国老年人使用大麻的比例达到 10.3%。随着时间的推移,人们对大麻的态度也发生了变化,5 名调查对象中有 4 人目前持赞成态度。态度和居住州与当前的使用情况有关。在 2016 年和 2018 年,大麻使用者报告的疼痛程度更高,更有可能使用处方阿片类药物,并报告活动受限。没有观察到大麻使用与睡眠问题或同时使用医疗保健之间的关联:态度的转变和各州的大麻合法化似乎对中老年人很重要,到 2030 年,每 5 个 50 岁以上的人中就可能有 1 人使用大麻。美国老年人使用大麻的情况值得医疗服务提供者、项目管理人员和政策制定者给予更多关注,尤其是作为与处方类阿片相比的一种预防或减少伤害的策略。
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引用次数: 0
Outcomes of Person-Centered Planning in Medicaid Home- and Community-Based Services. 以人为本的规划在医疗补助家庭和社区服务中的成果。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-06-01 DOI: 10.1093/geront/gnae017
Natalie Chong, Joseph Caldwell, H Stephen Kaye, Monika Mitra

Background and objectives: Person-centered planning (PCP) allows recipients of home- and community-based service (HCBS) to plan services and supports according to their preferences and needs. The extent to which HCBS systems engage in PCP and evidence for the relationship between PCP and beneficiary outcomes are limited. We examine the prevalence of PCP among HCBS recipients and the relationship between PCP and person-reported outcomes.

Research design and methods: We used the 2018-2019 National Core Indicators-Aging and Disability survey, collected among adult Medicaid HCBS recipients in 12 states (n = 5,849). We examined 2 general PCP measures (1 on decision making and another on whether service plans reflected preferences/choices). We also constructed a scale to assess the fidelity of recipients' service planning meeting to the PCP process. Outcomes included unmet service needs and community living (i.e., participation, control, and satisfaction). We examined recipient characteristics associated with PCP and used adjusted logistic regression models to assess the relationship between PCP and outcomes.

Results: About 72% of HCBS recipients were involved in decision making, 72% reported their service plan reflected their preferences/choices, and 47% had meetings that scored "high fidelity" on the PCP fidelity scale. PCP measures were consistently related to lower likelihood of unmet service needs and greater likelihood of experiencing community living outcomes.

Discussion and implications: Findings suggest PCP is important for adequately meeting service needs and ensuring community living among HCBS beneficiaries. Additional standardized measures should be developed to facilitate quality improvement and accountability for delivering person-centered HCBS.

背景和目标:以人为本的规划(PCP)允许家庭和社区服务(HCBS)的受益人根据自己的偏好和需求来规划服务和支持。居家和社区服务系统参与 PCP 的程度以及 PCP 与受益人结果之间关系的证据都很有限。我们研究了在 HCBS 受助者中 PCP 的普遍程度,以及 PCP 与个人报告结果之间的关系:我们使用了 2018-2019 年国家核心指标--老龄和残疾调查,该调查是在 12 个州的成年医疗补助 HCBS 受助人中收集的(n = 5,849 人)。我们研究了两个一般的 PCP 测量(一个关于决策,另一个关于服务计划是否反映了偏好/选择)。我们还构建了一个量表来评估受助者的服务规划会议是否忠实于以人为本的规划流程。结果包括未满足的服务需求和社区生活(即参与、控制和满意度)。我们研究了与 "以人为本的规划 "相关的受助者特征,并使用调整后的逻辑回归模型来评估 "以人为本的规划 "与结果之间的关系:约 72% 的 HCBS 受助人参与了决策,72% 的受助人称他们的服务计划反映了他们的偏好/选择,47% 的受助人的会议在 PCP 忠诚度量表中得分 "高忠诚度"。PCP 措施始终与较低的未满足服务需求可能性和较高的社区生活成果可能性相关:研究结果表明,PCP 对于充分满足服务需求和确保 HCBS 受益人的社区生活非常重要。应制定更多标准化措施,以促进以人为本的 HCBS 的质量改进和问责。
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引用次数: 0
Coordinated Care Experiences Among Middle-Aged and Older Adults With Multiple Chronic Conditions: Characteristics, Correlates, and Consequences for Health and Healthcare Utilization. 患有多种慢性疾病的中老年人的协调护理经历:有多种慢性病的中老年人的协调护理经历:特征、相关因素以及对健康和医疗保健使用的影响》(Characteristics, Correlates, and Consequences for Health and Healthcare Utilization.
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-06-01 DOI: 10.1093/geront/gnae024
Weidi Qin, Viktoryia Kalesnikava, Linh Dang, Rodlescia S Sneed, Rossella Messina, Paola Rucci, Briana Mezuk

Background and objectives: Although coordinated care (CC) seeks to improve patient experiences and ultimately health outcomes, evidence from empirical research on the impacts of CC is mixed. This study examined the relationship between CC and healthcare outcomes over a 4-year period among older adults with multiple chronic conditions.

Research design and methods: This observational cohort study is based on data from the 2016-2020 Health and Retirement Study. Analysis is limited to respondents with 2+ chronic conditions who completed an experimental module on CC in 2016 (n = 906). Three domains of CC were assessed: perceptions, informal (family/friends) and formal (healthcare staff) tangible support, and technical support (using a "patient portal"). The longitudinal relationship between CC and health (e.g., pain, functioning, and self-rated health [SRH]) and healthcare (e.g., doctor visits, hospitalization, and care satisfaction) outcomes was investigated using mixed-effects models.

Results: Better perceptions of CC were associated with lower odds of ADL limitations (Odds ratio [OR] = 0.91; 95% CI = 0.84-0.99) and greater satisfaction with care (B = 0.04, 95% CI = 0.02-0.06). Receipt of more informal tangible support was associated with 1.34 higher odds of ADL limitations (95% CI = 1.19-1.51) and 1.74 higher odds of hospitalization (95% CI = 1.07-1.21). Use of technical support was associated with better SRH and greater satisfaction with care.

Discussion and implications: The longitudinal relationship between CC and health is multifaceted. Although positive perceptions and more technical support have beneficial effects on health outcomes, higher utilization of tangible support may reflect a higher demand among older adults with more complex healthcare needs.

背景和目标:虽然协调护理(CC)旨在改善患者的就医体验并最终提高医疗效果,但有关 CC 影响的实证研究证据却不尽相同。本研究探讨了在四年时间里,协调护理与患有多种慢性疾病的老年人的医疗保健结果之间的关系:本观察性队列研究基于 2016-2020 年健康与退休研究的数据。分析对象仅限于2016年完成CC实验模块的患有2种以上慢性病的受访者(n = 906)。对 CC 的三个领域进行了评估:认知、非正式(家人/朋友)和正式(医护人员)有形支持以及技术支持(使用 "患者门户")。采用混合效应模型研究了CC与健康(如疼痛、功能、自评健康)和医疗(如就诊、住院、护理满意度)结果之间的纵向关系:结果:对 CC 感知的改善与较低的功能障碍几率(Odds ratio (OR)=0.92; 95% CI=0.88-0.99)和较高的护理满意度(B=0.04, 95% CI=0.02-0.05)相关。获得更多非正式有形支持与 ADL 受限几率增加 2.97(95% CI:1.69-5.22)和住院几率增加 1.77(95% CI=1.32-2.38)有关。使用技术支持与更好的自我健康评价和更高的护理满意度相关:CC与健康之间的纵向关系是多方面的。虽然积极的认知和更多的技术支持对健康结果有益,但有形支持的更高利用率可能反映了具有更复杂医疗保健需求的老年人对有形支持的更高需求。
{"title":"Coordinated Care Experiences Among Middle-Aged and Older Adults With Multiple Chronic Conditions: Characteristics, Correlates, and Consequences for Health and Healthcare Utilization.","authors":"Weidi Qin, Viktoryia Kalesnikava, Linh Dang, Rodlescia S Sneed, Rossella Messina, Paola Rucci, Briana Mezuk","doi":"10.1093/geront/gnae024","DOIUrl":"10.1093/geront/gnae024","url":null,"abstract":"<p><strong>Background and objectives: </strong>Although coordinated care (CC) seeks to improve patient experiences and ultimately health outcomes, evidence from empirical research on the impacts of CC is mixed. This study examined the relationship between CC and healthcare outcomes over a 4-year period among older adults with multiple chronic conditions.</p><p><strong>Research design and methods: </strong>This observational cohort study is based on data from the 2016-2020 Health and Retirement Study. Analysis is limited to respondents with 2+ chronic conditions who completed an experimental module on CC in 2016 (n = 906). Three domains of CC were assessed: perceptions, informal (family/friends) and formal (healthcare staff) tangible support, and technical support (using a \"patient portal\"). The longitudinal relationship between CC and health (e.g., pain, functioning, and self-rated health [SRH]) and healthcare (e.g., doctor visits, hospitalization, and care satisfaction) outcomes was investigated using mixed-effects models.</p><p><strong>Results: </strong>Better perceptions of CC were associated with lower odds of ADL limitations (Odds ratio [OR] = 0.91; 95% CI = 0.84-0.99) and greater satisfaction with care (B = 0.04, 95% CI = 0.02-0.06). Receipt of more informal tangible support was associated with 1.34 higher odds of ADL limitations (95% CI = 1.19-1.51) and 1.74 higher odds of hospitalization (95% CI = 1.07-1.21). Use of technical support was associated with better SRH and greater satisfaction with care.</p><p><strong>Discussion and implications: </strong>The longitudinal relationship between CC and health is multifaceted. Although positive perceptions and more technical support have beneficial effects on health outcomes, higher utilization of tangible support may reflect a higher demand among older adults with more complex healthcare needs.</p>","PeriodicalId":51347,"journal":{"name":"Gerontologist","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11127105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139991699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Exergame Telerehabilitation in Persons With Subjective Cognitive Decline. 外部游戏远程康复对主观认知能力下降者的影响
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-06-01 DOI: 10.1093/geront/gnae028
Dereck L Salisbury, Keenan A Pituch, Fang Yu

Background and objectives: The primary aim of this Stage IB randomized controlled trial (RCT) was to test the preliminary effects of a dual-task exergaming telerehabilitation intervention on cognition and aerobic fitness, compared to aerobic exercise (AEx) only and attention control (stretching) in older adults with subjective cognitive decline.

Research design and methods: This RCT randomized 39 participants on a 2:1:1 allocation ratio to supervised exergame (n = 20), AEx (n = 11), and stretching (n = 8) for 12 weeks. The dual-task exergaming was concurrent moderate-intensity cycling and BrainFitRx cognitive telerehabilitation. Cognition was assessed by NIH Toolbox Cognitive Battery and aerobic fitness by 6-minute walk test (6MWT) and shuttle walk test.

Results: The participants were 74.6 (7.4) years old and 69% were female. The effect of time was significant, F(1, 23.9) = 13.16, p = .001, for the Fluid Composite score, and significant within-group changes were seen for the exergame group, t(14.08) = 2.53, p = .024, d = 0.33. Between-group changes did not reach significant levels for any cognitive test. Between-group changes for the 6MWT were not significant.

Discussion and implications: The exergame participants further improved their fluid cognition, whereas the AEx and stretching groups did not, indicating a potential synergistic effect from AEx and cognitive training. The aerobic fitness changes were similar between the exergame and AEx-only groups, indicating that the feasibility of adding cognitive training to AEx concurrently without sacrificing gains in aerobic fitness from AEx. This study shows the flexibility of exergame delivery and its potentially therapeutic effects in persons at risk for Alzheimer's dementia.

Clinical trial registration number: NCT04311736.

背景与目的这项IB阶段随机对照试验(RCT)的主要目的是,与仅进行有氧运动(AEx)和注意力控制(拉伸)相比,测试双任务电子游戏远程康复干预对SCD老年人认知和有氧健身的初步效果:该研究按照2:1:1的分配比例将39名参与者随机分配到有监督的电子游戏(20人)、有氧运动(11人)和伸展运动(8人)中,为期12周。双任务游戏是同时进行中等强度的自行车运动和 BrainFitRx® 认知远程康复训练。认知能力由 NIH 工具箱认知电池评估,有氧体能由 6 分钟步行测试(6MWT)和穿梭步行测试评估:结果:参与者的年龄为 74.6 (7.4)岁,69% 为女性。流体综合评分的时间效应显著,F(1,23.9) = 13.16,p =.001;外显子游戏组的组内变化显著,t(14.08) = 2.53,p = .024,d = 0.33。在任何认知测试中,组间变化均未达到显著水平。6MWT 的组间变化不显著:外显子游戏参与者进一步提高了流体认知能力,而 AEx 组和拉伸组则没有,这表明 AEx 和认知训练可能会产生协同效应。外显子游戏组和仅进行 AEx 的组别之间的有氧体能变化相似,这表明在 AEx 中同时添加认知训练的可行性,而不会牺牲 AEx 带来的有氧体能收益。这项研究显示了外显子游戏的灵活性及其对阿尔茨海默氏症痴呆症高危人群的潜在治疗效果。
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引用次数: 0
Difference-Making Pathways to Frailty Through Social Factors: A Configurational Analysis. 通过社会因素导致虚弱的差异形成途径:配置分析。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-06-01 DOI: 10.1093/geront/gnad173
Chava Pollak, Joe Verghese, Helena M Blumen

Background and objectives: Social disconnection is highly prevalent in older adults and is associated with frailty. It is unclear which aspects of social disconnection are most associated with frailty, which ones are difference-making, and which combination of social factors are directly linked to frailty.

Research design and methods: We conducted a secondary coincidence analysis (CNA) of 1,071 older adults from the Rush Memory and Aging Project (mean age 79.3 ± 7.1; 75.8% female) to identify combinations of social factors that are difference-making for frailty. We included 7 demographic (e.g., age, sex, socioeconomic status) and structural (e.g., social network), functional (e.g., social support, social activity), and quality (e.g., loneliness) aspects of social connection. An established cut score of 0.2 on a frailty index was used to define frailty as the outcome.

Results: CNA produced 46 solution models for the presence of frailty in the data set. The top-scoring model was underfit, leaving a final complex solution path for frailty with the highest fit-robustness score that met the fit parameter cutoffs. We found that the combination of loneliness, low social activity, and older age was present 82% of the time when frailty was present.

Discussion and implications: The combination of loneliness, social activity, and old age is difference-making for frailty, and supports the inclusion of social factors in frailty prevention and intervention. Further research is needed in diverse data sets to better understand the interrelationships between the 3 aspects of social connection and frailty.

背景和目的:社会脱节在老年人中非常普遍,并且与虚弱有关。目前还不清楚哪些方面的社会脱节与虚弱最相关,哪些方面的社会脱节会造成差异,以及哪些社会因素的组合与虚弱直接相关:我们对拉什记忆与老龄化项目(Rush Memory and Aging Project)中的 1071 名老年人(平均年龄为 79.3 ± 7.1 岁;75.8% 为女性)进行了二次巧合分析(CNA),以确定哪些社会因素的组合会导致虚弱。我们纳入了社会联系的 7 个人口统计学方面(如年龄、性别、社会经济地位)、结构方面(如社会网络)、功能方面(如社会支持、社会活动)和质量方面(如孤独感)。虚弱指数的切分分数为 0.2,将虚弱定义为结果:结果:CNA 针对数据集中存在的虚弱问题生成了 46 个解决方案模型。得分最高的模型拟合度较低,最终留下了一条复杂的解决虚弱问题的路径,其拟合-稳健性得分最高,且符合拟合参数临界值。我们发现,在 82% 的情况下,孤独、社交活动少和年龄大是导致虚弱的原因:讨论与启示:孤独、社交活动少和年龄大这三者的结合会对虚弱产生影响,并支持将社会因素纳入虚弱的预防和干预中。要想更好地了解社会联系的三个方面与虚弱之间的相互关系,还需要对不同的数据集进行进一步研究。
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引用次数: 0
Sounds of Difference: A Typology of Reactions of People With Dementia to Individualized Music in the Presence of a Monitoring Person. 不同的声音:痴呆症患者在监护人在场的情况下对个性化音乐的反应类型。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-06-01 DOI: 10.1093/geront/gnad171
Nils F Töpfer, Lisa Schön, Elisabeth Jakob, Mareike C Hillebrand, Jo Reichertz, Doreen Rother, Lisette Weise, Gabriele Wilz

Background and objectives: Despite promising effects of individualized music listening (IML) for people with dementia, the individualized nature and heterogeneity of reactions to IML remain underexplored. We aimed to develop an empirically derived typology of directly observed reactions of people with dementia to IML and propose recommendations for tailoring the intervention to the respective types.

Research design and methods: An ideal-type analysis was conducted on 108 video recordings of 45 people with mainly severe dementia (78% female, mean age of 83.02 years, all White participants) listening to recorded individualized music. Dimensions were identified for capturing similarities and differences between types.

Results: The analysis yielded 10 types of reactions ("expressing and sharing joy," "self-disclosure stimulated by music," "concentrated, absorbed listening," "blissful enjoyment," "experience of the music as bittersweet," "sharing memories," "releasing tension," "tensing up and rejecting," "predominant search for social exchange," "no interpretable reaction") and 3 dimensions ("valence" from negative to positive, "arousal" from calm to activated, "communicative activity" from defensive/resistant to proactive), resulting in a three-dimensional coordinate system, providing a holistic representation and facilitating a systematic contrast of identified reaction types to IML.

Discussion and implications: Reactions to IML were influenced by the interaction with the project staff, who monitored the sessions. Based on these observations, we propose recommendations for tailoring both the behavior of the monitoring person (e.g., engaging in synchronous activities like clapping along) and the setup of the intervention (e.g., communal vs individual listening) to each type, which may improve the effects of IML.

背景和目的:尽管个性化音乐聆听(IML)为痴呆症患者带来了可喜的效果,但对IML反应的个性化和异质性仍未得到充分探索。我们的目的是根据经验,对直接观察到的痴呆症患者对 IML 的反应进行分类,并针对不同类型的反应提出相应的干预建议:我们对45名主要患有严重痴呆症的患者(78%为女性,平均年龄83.02岁,均为白人)聆听个性化音乐录音的108段视频录像进行了理想类型分析。结果:分析得出了 10 种反应类型("表达和分享快乐"、"由音乐激发的自我披露"、"专注、全神贯注的聆听"、"幸福的享受"、"对音乐苦乐参半的体验"、"分享回忆"、"释放紧张"、"紧张和拒绝"、"主要寻求社会交流"、"无可知反应")和三个维度("情绪 "从消极到积极,"唤醒 "从平静到活跃,"交流活动 "从防御/抵制到主动),从而形成一个三维坐标系,提供了一个整体表征,便于对已识别的 IML 反应类型进行系统对比。讨论和启示对 IML 的反应受到与项目人员互动的影响,项目人员对会议进行了监督。根据这些观察结果,我们提出了一些建议,以便针对每种类型的反应,调整监测人员的行为(如参与拍手等同步活动)和干预措施的设置(如集体聆听与个人聆听),从而提高 IML 的效果。
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引用次数: 0
Psychological Disorders Linked to Osteoporosis Diagnoses in a Population-Based Cohort Study of Middle and Older Age United States Adults. 美国中老年人群队列研究中与骨质疏松症诊断相关的心理障碍。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-06-01 DOI: 10.1093/geront/gnae027
K Godde, Margaret Gough Courtney, Josephine Roberts

Background and objectives: Although it is well established that psychological disorders and osteoporosis risk are linked, how the relationship manifests is not. This study examines depressive symptoms and a history of psychological problems as potential risk factors for osteoporosis diagnosis, adjudicating between 4 theoretical models rarely tested together. We analyze these models across multiple domains (i.e., demographic, socioeconomic, and health-related), while accounting for bone mineral density (BMD) scans, which have been shown to improve health equity across sex and racial/ethnic identities.

Research design and methods: Data from the 2012-2016, nationally representative, population-based, cohort Health and Retirement Study (N = 18,224-18,359) were used to estimate 4 logistic regression models with the outcome of osteoporosis diagnosis. Approximately 50% of the sample identified as female and 50% as male, while about 81% identified as White/European American, 11% as Black/African American, and 8% as another race/ethnicity. The key independent variables were depressive symptoms-measured using two common scales-and a history of psychological problems.

Results: A history of psychological problems and one depressive symptoms measure were associated with the odds of osteoporosis diagnosis in the presence of other known risk factors for osteoporosis.

Discussion and implications: Support for the theoretical models was limited. Evidence suggests possible directionality; a history of psychological distress may be a risk factor for osteoporosis, though we cannot rule out the other direction. Public health professionals and healthcare providers should consider a history of psychological problems as a risk factor for osteoporosis when deciding whether to recommend a BMD scan.

背景和目的:尽管心理障碍与骨质疏松症风险之间存在联系已是公认的事实,但这种关系是如何表现出来的却并不清楚。本研究将抑郁症状和心理问题史作为骨质疏松症诊断的潜在风险因素进行研究,并对很少同时进行测试的四种理论模型进行判定。我们从多个领域(即人口、社会经济和健康相关领域)对这些模型进行了分析,同时考虑到了骨矿物质密度(BMD)扫描,该扫描已被证明能改善不同性别和种族/民族身份的健康公平性:研究使用了 2012-2016 年具有全国代表性、基于人口的队列健康与退休研究(N=18,224 至 18,359)的数据,以骨质疏松症诊断为结果,估计了四个逻辑回归模型。样本中约 50% 为女性,50% 为男性,约 81% 为白人/欧美人,11% 为黑人/非洲裔美国人,8% 为其他种族/人种。主要的自变量是抑郁症状(使用两个通用量表测量)和心理问题史:结果:在存在其他已知骨质疏松症风险因素的情况下,心理问题史和一种抑郁症状测量与骨质疏松症诊断几率相关:对理论模型的支持有限。证据表明可能存在方向性;心理困扰史可能是骨质疏松症的一个风险因素,但我们不能排除另一个方向。公共卫生专业人员和医疗服务提供者在决定是否建议进行 BMD 扫描时,应将心理问题史视为骨质疏松症的风险因素。
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引用次数: 0
(Re-) Defining "Successful Aging" as the Endpoint in Clinical Trials? Current Methods, Challenges, and Emerging Solutions. (Re-) 将 "成功衰老 "定义为临床试验的终点?当前的方法、挑战和新兴解决方案。
IF 5.7 2区 医学 Q1 Medicine Pub Date : 2024-05-30 DOI: 10.1093/geront/gnae058
Anton Schönstein

Background and objectives: "Successful aging" as defined in Rowe & Kahn's model aims to include the major domains of aging under a single overarching concept. From here the question arises how "successful aging" itself can be implemented as an endpoint in clinical research in a way that it is compliant to methodological regulatory framework and recommendations as formulated, for example, by the FDA. This article discusses from an applied perspective approaches and examples of how "successful aging" as a multi domain concept can be put into measurement practice.

Research design and methods: Narrative literature review.

Results: Existing methods of merging insights from, e.g., functional, social, and cognitive outcomes, can fail to perform under conditions of extreme heterogeneity, as often present in samples of older adults. In research on rare diseases, the methodological approach of a Multi Domain Responder Index (MDRI) has been proposed to handle heterogeneity. MDRIs may also provide a solution to combine aging outcomes from different domains into a single "successful aging" endpoint. However, strict measurement criteria will need to be fulfilled to find acceptance in decision making and validated meaningful change thresholds are a critical prerequisite.

Discussion and implications: Gerontology can spearhead methodological approaches of handling multidimensional measurement under heterogeneity by validating a "successful aging" MDRI suitable for use as an endpoint in clinical research.

背景和目标:Rowe & Kahn 模型中定义的 "成功老龄化 "旨在将老龄化的主要领域纳入一个单一的总体概念中。由此产生的问题是,如何在临床研究中将 "成功老龄化 "本身作为终点,并使其符合方法监管框架和建议,例如美国食品药物管理局(FDA)制定的方法和建议。本文从应用的角度讨论了如何将 "成功老龄化 "这一多领域概念付诸测量实践的方法和实例:研究设计与方法:叙事性文献综述:将功能、社会和认知结果等方面的见解合并在一起的现有方法,在极端异质性条件下可能会失效,而老年人样本中经常出现这种情况。在罕见病研究中,有人提出了多领域应答指数(MDRI)的方法来处理异质性。多领域反应指数还可以提供一种解决方案,将不同领域的衰老结果合并为一个 "成功衰老 "终点。不过,要想在决策中获得认可,还需要满足严格的测量标准,而经过验证的有意义变化阈值则是一个关键的先决条件:老年学可以通过验证适合用作临床研究终点的 "成功老龄化 "MDRI,在异质性条件下率先采用多维测量方法。
{"title":"(Re-) Defining \"Successful Aging\" as the Endpoint in Clinical Trials? Current Methods, Challenges, and Emerging Solutions.","authors":"Anton Schönstein","doi":"10.1093/geront/gnae058","DOIUrl":"https://doi.org/10.1093/geront/gnae058","url":null,"abstract":"<p><strong>Background and objectives: </strong>\"Successful aging\" as defined in Rowe & Kahn's model aims to include the major domains of aging under a single overarching concept. From here the question arises how \"successful aging\" itself can be implemented as an endpoint in clinical research in a way that it is compliant to methodological regulatory framework and recommendations as formulated, for example, by the FDA. This article discusses from an applied perspective approaches and examples of how \"successful aging\" as a multi domain concept can be put into measurement practice.</p><p><strong>Research design and methods: </strong>Narrative literature review.</p><p><strong>Results: </strong>Existing methods of merging insights from, e.g., functional, social, and cognitive outcomes, can fail to perform under conditions of extreme heterogeneity, as often present in samples of older adults. In research on rare diseases, the methodological approach of a Multi Domain Responder Index (MDRI) has been proposed to handle heterogeneity. MDRIs may also provide a solution to combine aging outcomes from different domains into a single \"successful aging\" endpoint. However, strict measurement criteria will need to be fulfilled to find acceptance in decision making and validated meaningful change thresholds are a critical prerequisite.</p><p><strong>Discussion and implications: </strong>Gerontology can spearhead methodological approaches of handling multidimensional measurement under heterogeneity by validating a \"successful aging\" MDRI suitable for use as an endpoint in clinical research.</p>","PeriodicalId":51347,"journal":{"name":"Gerontologist","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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