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Alzheimer's Disease Risk Reduction Health Coaching: Comparative Analysis. 阿尔茨海默病风险降低健康辅导:比较分析。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-10-01 DOI: 10.1093/geront/gnae106
Faika Zanjani, Brian Battle, Joann Richardson

Background and objectives: Recent guidelines point to lifestyle as a tool for decreasing Alzheimer's disease (AD) risk. To address the limited practice and availability of AD risk reduction interventions, this study aimed to explore the feasibility of a community-level lifestyle intervention targeting high-risk groups.

Research design and methods: Diverse older adults (60+) living in the Richmond, VA, local area, with the following risk factors, incomes below $12,000/year and managing diabetes or cardiovascular disease, were offered weekly lifestyle telephone health coaching for 12 weeks in 2019-2020 (intervention group). The health coaching sessions provided Alzheimer's disease (AD) lifestyle risk reduction education and goal setting/planning. The intervention sample (n = 40, mean age 68 years (range: 60-76 years), was 90% African American/Black (n = 36) and 45% male (n = 18). Thereafter, in 2021-2022, n = 37 individuals in the same area were recruited as a comparison group and not given health coaching (control group), mean age of 65.5 years (range: 57-83 years), 92% African American/Black (n = 34), and 50% male (n = 18).

Results: Repeated-measures intervention effects were seen for cognitive ability, indicating greater improvement in the intervention group (p < .01). Significant difference scores indicated greater cognitive ability (p < .01) and physical activity (p < .001) gains in the intervention group, with intervention subjects with reported memory problems showed relatively less physical activity gains (p < .05).

Discussion and implications: This work creates the impetus for future large-scale AD risk reduction investigations to mitigate and improve modifiable risk among diverse older adults. Our positive trends in AD risk reduction support telephone-based health coaching as a feasible AD risk reduction intervention.

背景和目的:最新指南指出,生活方式是降低阿尔茨海默病(AD)风险的一种工具。为了解决减少阿尔茨海默病风险干预措施的实践和可用性有限的问题,本研究旨在探索针对高风险人群的社区生活方式干预措施的可行性:在 2019-2020 年期间,为居住在弗吉尼亚州里士满当地、具有以下风险因素(收入低于 12,000 美元/年、患有糖尿病或心血管疾病)的多元化老年人(60 岁以上)提供为期 12 周的每周生活方式电话健康指导(干预组)。健康指导课程提供减少亚健康生活方式风险教育和目标设定/规划。干预样本(40 人,平均年龄 68 岁(60-76 岁))中 90% 为非裔美国人/黑人(36 人),45% 为男性(18 人)。此后,在 2021-2022 年,在同一地区招募了 37 人作为对比组,不提供健康指导(对照组),平均年龄 65.5 岁(范围:57-83 岁),92% 为非洲裔美国人/黑人(人数=34),50% 为男性(人数=18):结果:在认知能力方面出现了重复测量干预效果,表明干预组的改善幅度更大(讨论和影响:这项研究为未来大规模降低注意力缺失症风险调查提供了动力,以减轻和改善不同老年人的可调节风险。我们在降低注意力缺失症风险方面的积极趋势支持将电话健康指导作为一种可行的降低注意力缺失症风险干预措施。
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引用次数: 0
Finding the Balance to Quiet the Striving: The Difference Between Successful Aging and Wise Aging. 寻找平衡,平息奋斗:成功老龄化与智慧老龄化的区别。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-09-05 DOI: 10.1093/geront/gnae126
Judith Glück, Luisa Jäger, Irina Auer-Spath, Imke Harbig

This paper draws on wisdom and lifespan development research to propose a conception of "wise aging", which may become particularly relevant in very old age as people's capacities for successful aging decline. We propose that three types of balance distinguish wise aging from successful aging. First, wisdom balances one's own interest with a greater good, emphasizing self-transcendence and compassion. Second, wisdom balances control striving with acceptance of uncontrollability. Wise aging involves a realistic awareness of one's decreasing levels of control and one's interconnectedness to and dependence on other people. Third, wisdom acknowledges, regulates, and balances positive and negative affect. Wise aging involves the ability to appreciate and relish the joys of life, but also to accept and embrace more negative emotions and fully support others going through different times.

本文借鉴智慧和寿命发展研究的成果,提出了 "智慧老龄化 "的概念,随着人们成功老龄化的能力下降,这一概念在老年阶段可能变得尤为重要。我们提出,智慧老龄化与成功老龄化之间存在三种平衡。首先,智慧是在自身利益与更大利益之间取得平衡,强调自我超越和同情心。其次,智慧在努力控制与接受不可控性之间取得平衡。智慧的老龄化包括现实地认识到自己的控制能力不断下降,以及自己与他人的相互联系和依赖。第三,智慧承认、调节和平衡积极和消极的影响。智慧的老龄化包括有能力欣赏和享受生活的乐趣,同时也能接受和包容更多的负面情绪,并全力支持其他经历不同时期的人。
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引用次数: 0
Exploring Older Adults' Subjective Views on Aging Positively: Development and Validation of the Positive Aging Scale. 探索老年人对积极老龄化的主观看法:积极老龄化量表的开发与验证。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-09-01 DOI: 10.1093/geront/gnae088
Miriam Sang-Ah Park, Stephen Badham, Samuel Vizcaino-Vickers, Emanuele Fino

Background and objectives: Historically, aging research has focused primarily on health deterioration and negative aspects associated with aging. This has limited the scope of our understanding of the experience of aging and the relationships between aging and well-being from an integrative biopsychosocial perspective. In the same vein, there is a lack of reliable and valid assessments of aging that capture the positive aspects that characterize and improve the subjective experience of this period of life, particularly one that focuses on psychosocial well-being, including meaningful experiences and activities, group memberships, and general abilities. This study presents the development and validation of the Positive Aging Scale (PAS), a novel self-report assessment.

Research design and methods: This was an online cross-sectional study conducted on 501 UK residents aged ≥60 years. A number of self-reported items and measures of positive aging, general health, well-being, and cognitive functioning were administered to the sample. We used exploratory and confirmatory factor analyses and assessed the dimensionality, reliability, and concurrent criterion-related validity of the PAS.

Results: The results suggested that a unidimensional solution represents the data well, with the positive aging factor adequately loading on 8 items, and the solution showing factorial invariance between young-old and old participants (i.e., ≥75 years). Total PAS scores positively correlate with general health, well-being, and cognitive functioning.

Discussion and implications: The PAS demonstrated strong psychometric properties and the findings highlight correlations between the PAS and key outcomes of positive aging, including general health. Implications for research and interventions are discussed.

背景和目的:从历史上看,老龄化研究主要集中在与老龄化相关的健康恶化和消极方面。这限制了我们从综合生物-心理-社会角度对衰老体验以及衰老与幸福之间关系的理解范围。同样,我们也缺乏可靠、有效的老龄化评估,这些评估能够捕捉老龄化的积极方面,并改善这一时期生活的主观体验,特别是侧重于社会心理健康的评估,包括有意义的经历和活动、团体成员资格和一般能力。本研究介绍了积极老龄化量表(PAS)的开发和验证情况,这是一种新颖的自我报告评估方法:这是一项在线横断面研究,研究对象为 501 名年龄≥ 60 岁的英国居民。对样本进行了一系列自我报告项目和积极老龄化、一般健康、幸福感和认知功能的测量。我们使用了探索性和确认性因素分析,评估了 PAS 的维度、可靠性和并行标准相关有效性:结果表明,单维度解法很好地代表了数据,积极的老龄化因子在八个项目上有充分的负荷,而且该解法在年轻参与者和老年参与者(即年龄≥ 75 岁)之间表现出因子不变性。PAS 总分与总体健康、幸福感和认知功能呈正相关:PAS 具有很强的心理测量特性,研究结果突出了 PAS 与积极老龄化的主要结果(包括总体健康状况)之间的相关性。本文还讨论了研究和干预措施的意义。
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引用次数: 0
Comparing Unmet Service Needs Between Rural and Urban Family Caregivers of People Living With Alzheimer's Disease and Related Dementias: A Multisite Study. 比较农村和城市阿尔茨海默病及相关痴呆症患者家庭照顾者未得到满足的服务需求:多地点研究。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-09-01 DOI: 10.1093/geront/gnae083
Christina E Miyawaki, Angela McClellan, David Russell, Erin D Bouldin

Background and objectives: The scarcity of resources and available caregiving services in rural areas in the United States has been well documented. However, less research has compared unmet service needs between caregivers of people with Alzheimer's disease and related dementias (ADRD) in rural versus urban areas.

Research design and methods: Using semistructured interviews guided by theories of health service use and dependent care, we interviewed 20 family caregivers residing in rural areas of Western North Carolina and 18 caregivers within the urban setting of Houston, Texas, and compared their unmet service needs and contextual factors that facilitate their service use.

Results: Thematic analyses revealed similar unmet service needs among rural and urban caregivers; however, the ways they approached and solved their challenges differed. Caregivers in rural areas wished for more information and caregiver support whereas urban caregivers looked for information they needed until they found the answers. Rural caregivers expressed guilt about using services because they felt they were limited and zero-sum whereas urban caregivers shared available resources so that other caregivers could use them as well. Unmet service needs for urban caregivers included more racially and ethnically specific services for people with ADRD in their ethnic-specific languages and foods while rural caregivers' cultural needs were not racially and ethnically specific but for more place-specific services.

Discussion and implications: Recommendations for rural caregivers included utilizing online and virtual opportunities and expanding their reach across the United States. For urban caregivers, increasing culturally tailored service options would likely increase access and use.

背景和目标:美国农村地区资源匮乏、可提供的护理服务稀缺,这一点已得到充分证实。然而,对农村和城市地区阿尔茨海默氏症及相关痴呆症(ADRD)患者护理者之间未得到满足的服务需求进行比较的研究较少:在健康服务使用和依赖性护理理论的指导下,我们采用半结构式访谈法,对居住在北卡罗来纳州西部农村地区的 20 名家庭护理者和居住在德克萨斯州休斯顿城市环境中的 18 名护理者进行了访谈,并比较了他们未得到满足的服务需求和促进他们使用服务的环境因素:主题分析表明,农村和城市照顾者未得到满足的服务需求相似;但是,他们应对和解决挑战的方式不同。农村地区的照护者希望获得更多信息和照护者支持,而城市地区的照护者则一直在寻找他们需要的信息,直到找到答案。农村地区的照护者对使用服务表示内疚,因为他们觉得这些服务是有限的、零和的,而城市地区的照护者则分享现有资源,以便其他照护者也能使用。城市照顾者尚未满足的服务需求包括为患有 ADRD 的人提供更多具有种族和民族特色的服务,使用他们本民族特有的语言和食物,而农村照顾者的文化需求并不具有种族和民族特色,而是需要更多具有地方特色的服务:对农村照顾者的建议包括利用在线和虚拟机会,并将其覆盖范围扩大到全美国。对于城市护理者而言,增加针对不同文化的服务选择可能会增加他们获得和使用服务的机会。
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引用次数: 0
Walking and Social Reminiscence in Gentrifying Neighborhoods: Feasibility and Impact on Cognitive, Physical, and Mental Health Among Older Black Adults in the SHARP Study. 贫民区的步行和社交回忆:SHARP研究中黑人老年人认知、身体和心理健康的可行性及影响》。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-09-01 DOI: 10.1093/geront/gnae019
Raina Croff, Sophia Aron, Anne Wachana, Patrice Fuller, Nora Mattek, Juell Towns, Jeffrey Kaye

Background and objectives: Two exploratory 6-month pilots of triadic walking with culturally celebratory social reminiscence in gentrifying neighborhoods tested feasibility and health impact among normal and mildly cognitively impaired (MCI) older Black adults.

Research design and methods: Fourteen triads walked 1-mile 3×/week, using a navigational application with image-based reminiscence prompts. Focus groups evaluated perceived health impact and experience. Primary outcome measures were program evaluations (feasibility), pre-post self-report health, Montreal Cognitive Assessment, blood pressure, and weight. Analysis used mean rank scores for program evaluations, pre-post paired t-tests for health outcomes, and thematic coding for 30 focus groups.

Results: Feasibility: Retention was 74% and 86% for pilots, and 100% and 92%, respectively, were "extremely likely" to recommend to friends/family. Mean rank scores indicated appropriate pace and dose, effective conversational prompts, and program readiness with minor changes. Health impact: Self-rated health, mood, activity levels, and energy improved, days feeling downhearted decreased, and days feeling calm/peaceful were maintained or improved. Among Cohort 2, cognitive assessment scores were maintained or improved for 67%; for MCI, 76% had mean improvement of 2.4 (p = .045). Blood pressure and weight decreased for 78% and 44%, respectively. Focus groups: Perceived impact of triadic walking included increased physical and social activity outside the program, increased awareness of cognitive decline risk and personal agency, and deep-seated sense of community connection.

Discussion and implications: Triadic walking provides structure, accountability, connection, and purpose, motivating sustained engagement. Walking programs that center socialization, particularly within culturally meaningful contexts, may be more effective among older Black adults.

Clinical trial registration number: NCT05906654; NCT05906667.

背景和目标:在绅士化社区开展了两项为期 6 个月的三人步行探索性试点项目,在正常和轻度认知障碍(MCI)的黑人老年人中测试了三人步行的可行性和对健康的影响:14 个三人小组每周 3 次步行 1 英里,使用带有基于图像的回忆提示的导航应用程序。焦点小组对感知到的健康影响和体验进行评估。主要结果指标包括项目评估(可行性)、事后自我健康报告、蒙特利尔认知评估、血压和体重。分析使用了项目评估的平均等级分、健康结果的前后配对 t 检验以及 30 个焦点小组的主题编码:结果:可行性:试点项目的保留率分别为 74% 和 86%,92% 的人 "极有可能 "向朋友/家人推荐。平均等级分显示出适当的节奏和剂量、有效的会话提示以及稍作改动后的计划准备就绪。对健康的影响:自评健康状况、情绪、活动水平和精力均有所改善,心情低落的天数有所减少,平静/安宁的天数保持或有所改善。在第二组人群中,67%的人的认知评估得分保持或有所提高;76%的人的 MCI 平均得分提高了 2.4 分(p=.045)。血压和体重分别下降的比例为 78% 和 44%。焦点小组:他们认为三联行走的影响包括:增加了计划之外的体育和社交活动,提高了对认知能力下降风险和个人能力的认识,以及深层次的社区联系感:三人步行计划提供了结构、责任、联系和目的,激励人们持续参与。以社交为中心的步行计划,尤其是在有文化意义的背景下,可能对黑人老年人更有效。
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引用次数: 0
Care-Resistant Behavior Trajectories During Mouth Care Among Nursing Home Residents With Dementia. 痴呆症疗养院住户在口腔护理期间的护理抗拒行为轨迹。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-09-01 DOI: 10.1093/geront/gnae084
Chunhong Xiao, Frank Puga, Carolyn Pickering, Hsiao-Lan Wang, Maria Geisinger, Cindy Cain, Peng Li, Rita Jablonski

Background and objectives: This study examined day-to-day variation in care-resistant behaviors (CRBs) exhibited by persons living with dementia during mouth healthcare and the potential influence of time of day on CRB trajectories.

Research design and methods: A secondary analysis was conducted on a sample of 75 nursing home-dwelling persons living with dementia who exhibited CRBs during mouth care activities. Over 21 days, CRBs were measured using the revised Resistiveness to Care scale (RTC-r) during morning and afternoon mouth care sessions. Group-based trajectory modeling was used to identify trajectory patterns and assess differences between morning and afternoon CRB patterns.

Results: Three trajectory patterns were identified: morning CRB trajectory patterns showed 50.6% of persons living with dementia had consistently low RTC-r scores, 37.5% of persons living with dementia exhibited fluctuating, moderate RTC-r scores, and 11.9% exhibited RTC-r scores that started high and then decreased over time. Similarly, CRB trajectory patterns during afternoon mouth care showed a consistently low RTC-r score for 54.5% and a fluctuating moderate RTC-r score for 38.6% of persons living with dementia. However, the third CRB trajectory group followed a high-increasing trajectory, with RTC-r scores starting high and continuing to increase for 6.9% of persons living with dementia.

Discussion and implications: CRBs are dynamic and vary within days and over time; however, the time of the day is often not considered in interventions to manage CRBs. Thus, it is important to consider the timing of providing mouth care for persons living with dementia. Based on the characteristics of the trajectories, we suggest that morning mouth activities may be more efficient.

背景和目的:本研究探讨了痴呆症患者在口腔保健过程中表现出的护理抵抗行为(CRB)的日间变化,以及时间对CRB轨迹的潜在影响:对 75 名居住在养老院、在口腔护理活动中表现出 CRB 的痴呆症患者样本进行了二次分析。在 21 天内,在上午和下午的口腔护理过程中,使用修订后的护理抗拒量表 (RTC-r) 对 CRB 进行了测量。采用基于小组的轨迹模型来确定轨迹模式,并评估上午和下午 CRB 模式之间的差异:结果:确定了三种轨迹模式:上午的 CRB 轨迹模式显示,50.6% 的痴呆患者的 RTC-r 分数持续较低,37.5% 的痴呆患者的 RTC-r 分数波动适中,11.9% 的痴呆患者的 RTC-r 分数开始较高,随后随着时间的推移逐渐降低。同样,下午口腔护理期间的 CRB 轨迹模式显示,54.5% 的痴呆症患者的 RTC-r 得分持续较低,38.6% 的痴呆症患者的 RTC-r 得分波动适中。然而,第三组 CRB 轨迹则呈现出高增长轨迹,6.9% 的痴呆症患者的 RTC-r 分数从高分开始并持续上升:CRB 是动态的,在一天内和随着时间的推移而变化;然而,在管理 CRB 的干预措施中往往没有考虑一天中的时间。因此,考虑为痴呆症患者提供口腔护理的时间非常重要。根据轨迹的特点,我们认为早上的口腔活动可能更有效。
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引用次数: 0
COVID-19 Stress and Cognitive Disparities in Black, MENA, and White Older Adults. COVID-19 黑人、中东和北非以及白人老年人的压力与认知差异。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-08-01 DOI: 10.1093/geront/gnae073
Kristine J Ajrouch, Laura B Zahodne, Simon Brauer, Wassim Tarraf, Toni C Antonucci

Background and objectives: Population aging has led to an increased interest in cognitive health and, in particular, the role that stress plays in cognitive disparities. This paper extends previous work by characterizing coronavirus disease 2019 (COVID-19) stress type prevalence and its association with cognitive health in metro-Detroit among Black, Middle Eastern/Arab (MENA), and White older adults.

Research design and methods: Data come from a regionally representative sample of adults aged 65+ in metro-Detroit (N = 600; MENA n = 199; Black n = 205; White n = 196). We used generalized linear models to compare groups on sociodemographic, objective stress, and social stress indicators. Multiple group structural equation models evaluated whether COVID-19 stress predicted cognitive health and whether that association varied across racial/ethnic groups.

Results: MENA and Black older adults reported higher levels of objective stress than Whites. There were no racial/ethnic group differences in social stress. More objective stress was associated with better cognitive health, and more social stress was associated with worse cognitive health. The positive effect of objective stress was especially apparent for White older adults.

Discussion and implications: Though it appears that minority stress was not exacerbated in the context of pandemic stress, links between greater objective stress and better cognitive health apparent among White older adults were not evident among MENA or Black older adults. Broadening health disparities research by including underrepresented populations allows us to elevate scientific knowledge by clarifying what is universal and what is unique about the stress process.

背景和目的:人口老龄化导致人们越来越关注认知健康,尤其是压力在认知差异中所起的作用。本文通过描述 COVID-19 压力类型在底特律大都会区黑人、中东/阿拉伯(MENA)和白人老年人中的流行程度及其与认知健康的关系,对之前的工作进行了扩展:数据来自底特律大都会区具有地区代表性的 65 岁以上成年人样本(样本数=600;中东和北非=199;黑人=205;白人=196)。我们使用广义线性模型(GLMs)来比较各组的社会人口、客观压力和社会压力指标。多组结构方程模型(SEM)评估了 COVID-19 压力是否能预测认知健康,以及这种关联在不同种族/族裔群体之间是否存在差异:结果:中东和北非以及黑人老年人报告的客观压力水平高于白人。在社会压力方面没有种族/族裔群体差异。客观压力越大,认知健康状况越好,而社会压力越大,认知健康状况越差。客观压力对白人老年人的积极影响尤为明显:尽管在大流行压力的背景下,少数群体的压力似乎并没有加剧,但在白人老年人中,客观压力越大,认知健康越好,但在中东和北非以及黑人老年人中,这种联系并不明显。通过将代表性不足的人群纳入研究范围来扩大健康差异研究,使我们能够澄清压力过程中哪些是普遍的,哪些是独特的,从而提升科学知识。
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引用次数: 0
Are Virtual Assistants Trustworthy for Medicare Information: An Examination of Accuracy and Reliability. 虚拟助理提供的医疗保险信息是否可信?对准确性和可靠性的研究。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-08-01 DOI: 10.1093/geront/gnae062
Emily Langston, Neil Charness, Walter Boot

Background and objectives: Advances in artificial intelligence (AI)-based virtual assistants provide a potential opportunity for older adults to use this technology in the context of health information-seeking. Meta-analysis on trust in AI shows that users are influenced by the accuracy and reliability of the AI trustee. We evaluated these dimensions for responses to Medicare queries.

Research design and methods: During the summer of 2023, we assessed the accuracy and reliability of Alexa, Google Assistant, Bard, and ChatGPT-4 on Medicare terminology and general content from a large, standardized question set. We compared the accuracy of these AI systems to that of a large representative sample of Medicare beneficiaries who were queried twenty years prior.

Results: Alexa and Google Assistant were found to be highly inaccurate when compared to beneficiaries' mean accuracy of 68.4% on terminology queries and 53.0% on general Medicare content. Bard and ChatGPT-4 answered Medicare terminology queries perfectly and performed much better on general Medicare content queries (Bard = 96.3%, ChatGPT-4 = 92.6%) than the average Medicare beneficiary. About one month to a month-and-a-half later, we found that Bard and Alexa's accuracy stayed the same, whereas ChatGPT-4's performance nominally decreased, and Google Assistant's performance nominally increased.

Discussion and implications: LLM-based assistants generate trustworthy information in response to carefully phrased queries about Medicare, in contrast to Alexa and Google Assistant. Further studies will be needed to determine what factors beyond accuracy and reliability influence the adoption and use of such technology for Medicare decision-making.

背景和目的:基于人工智能的虚拟助手的进步为老年人在寻求健康信息时使用这种技术提供了潜在的机会。关于人工智能信任度的元分析表明,用户会受到人工智能受托人的准确性和可靠性的影响。我们对医疗保险查询回复的这些方面进行了评估:2023 年夏天,我们评估了 Alexa、Google Assistant、Bard 和 ChatGPT-4 在大型标准化问题集的医疗保险术语和一般内容方面的准确性和可靠性。我们将这些人工智能系统的准确性与二十年前查询的具有代表性的医疗保险受益人大样本的准确性进行了比较:结果发现,Alexa 和谷歌助手在术语查询方面的平均准确率为 68.4%,在一般医疗保险内容方面的平均准确率为 53.0%,而受益人的平均准确率为 68.4%。与普通医疗保险受益人相比,Bard 和 ChatGPT-4 能完美回答医疗保险术语查询,在一般医疗保险内容查询方面表现更好(Bard = 96.3%,ChatGPT-4 = 92.6%)。大约一个月到一个半月后,我们发现 Bard 和 Alexa 的准确率保持不变,而 ChatGPT-4 的表现略有下降,谷歌助手的表现略有上升:与 Alexa 和谷歌助手相比,基于 LLM 的助手在回答有关医疗保险的仔细措辞的询问时会生成值得信赖的信息。进一步的研究将需要确定除了准确性和可靠性之外,还有哪些因素会影响在医疗保险决策中采用和使用此类技术。
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引用次数: 0
Cognitive Impairment and Social Determinants of Health Among Indigenous Women. 土著妇女的认知障碍和健康的社会决定因素。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-08-01 DOI: 10.1093/geront/gnae072
Soonhee Roh, Yeon-Shim Lee, Heehyul Moon, Joel S Steele, Donald K Warne, Jung-Ah Lee

Background and objectives: Cognitive impairment and Alzheimer's disease and related dementias (ADRD) pose significant challenges for Indigenous populations, necessitating urgent research. Limited evidence suggests that high rates of ADRD among Indigenous peoples are associated with social determinants of health (SDOH), such as education, income, health literacy, religion, and social engagement.

Research design and methods: Collaborating with a Northern Plains tribe, participants were recruited 123 self-identified Indigenous women aged 40-70 through a comprehensive recruitment strategy. Employing the SDOH framework, the research assessed cognitive impairment and Alzheimer's disease knowledge (ADK), utilizing the Ascertain Dementia 8 and Alzheimer's disease knowledge scales (ADK-30). The investigation examined the relationships between selected SDOH variables and cognitive impairment status.

Results: More than half of the participants showed signs of cognitive impairment, which correlated with lower income and education levels. Increased knowledge about Alzheimer's disease, particularly in terms of treatment management and its life impact subscales, was associated with lower odds of cognitive impairment. Conversely, higher levels of depressive symptoms and participation in religious activities were linked to increased odds of cognitive impairment.

Discussion and implications: The findings underscore the importance of culturally grounded tools and SDOH frameworks tailored to Indigenous contexts in addressing ADRD disparities. Future research should integrate historical and cultural factors to advance health equity within Indigenous communities, ultimately mitigating the impact of ADRD and promoting overall well-being.

背景和目标:认知障碍和阿尔茨海默病及相关痴呆症(ADRD)给原住民带来了巨大挑战,亟需开展研究。有限的证据表明,原住民中阿兹海默症和相关痴呆症的高发病率与健康的社会决定因素(SDOH)有关,如教育、收入、健康知识、宗教和社会参与:与北部平原的一个部落合作,通过综合招募策略招募了 123 名年龄在 40 岁至 70 岁之间、自我认同的原住民妇女。研究采用 SDOH 框架,利用 Ascertain Dementia 8 和 AD 知识量表(ADK-30)评估认知障碍和阿尔茨海默病知识。调查研究了选定的 SDOH 变量与认知障碍状况之间的关系:结果:半数以上的参与者有认知障碍的迹象,这与较低的收入和教育水平有关。对阿尔茨海默病了解的增加,尤其是在治疗管理及其对生活影响的分量表方面,与认知障碍几率的降低有关。相反,抑郁症状和参与宗教活动的程度越高,认知障碍的几率越大:这些研究结果强调了针对土著背景的文化基础工具和 SDOH 框架在解决 ADRD 差异方面的重要性。未来的研究应结合历史和文化因素,促进原住民社区的健康公平,最终减轻 ADRD 的影响并促进整体福祉。
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引用次数: 0
Virtual Group Cognitive Stimulation Therapy for Dementia: Mixed-Methods Feasibility Randomized Controlled Trial. 治疗痴呆症的虚拟团体认知刺激疗法(vCST):混合方法可行性随机对照试验。
IF 4.6 2区 医学 Q1 GERONTOLOGY Pub Date : 2024-08-01 DOI: 10.1093/geront/gnae063
Aimee Spector, Nur Diyanah Abdul Wahab, Joshua Stott, Emily Fisher, Esther K Hui, Luke Perkins, Wing Gi Leung, Rachel Evans, Gloria Wong, Cerne Felstead

Background and objectives: Cognitive stimulation therapy (CST) is an evidence-based group intervention for people with dementia, with benefits for cognition and quality of life when delivered face-to-face. Many people are unable to attend face-to-face groups for reasons including health and transport issues. This study aimed to assess the feasibility and acceptability of online or "virtual" CST (vCST).

Research design and methods: Single-blind, randomized controlled feasibility design with qualitative interviews. Forty-six people with mild-to-moderate dementia were randomly allocated to attend either 14 sessions of twice-weekly vCST (n = 24) or treatment as usual (TAU, defined as usual care; n = 22) over 7 weeks. Cognition, quality of life, and depression were assessed pre- and posttreatment. Qualitative interviews (n = 16) with participants and carers were analyzed using thematic analysis.

Results: High levels of attendance, adherence, fidelity to the manual, and completion of outcomes were recorded. Recruitment appeared feasible although randomization may not have been acceptable to some. There were no statistical differences noted between vCST and TAU in any of the outcomes evaluated, although both quantitative and qualitative data indicated acceptability, with qualitative reports of improved outcomes including cognition.

Discussion and implications: vCST appeared feasible to deliver but did not result in any changes in outcomes, as expected from an underpowered feasibility trial. CST is the main psychosocial intervention delivered for dementia in UK memory services and globally, with many services moving towards virtual CST delivery. Therefore, a fully powered RCT of the effectiveness of vCST is feasible and justified.

背景和目的:认知刺激疗法(CST)是一项针对痴呆症患者的循证小组干预措施,通过面对面的方式对患者的认知能力和生活质量有益。由于健康和交通问题等原因,许多人无法参加面对面的小组活动。本研究旨在评估在线或 "虚拟 "CST(vCST)的可行性和可接受性:研究设计和方法:单盲、随机对照可行性设计和定性访谈。46名轻度至中度痴呆症患者被随机分配参加为期七周、每周两次、每次14节的vCST(n = 24)或常规治疗(TAU,定义为常规护理;n = 22)。对治疗前后的认知、生活质量和抑郁情况进行评估。采用主题分析法对参与者和照护者的定性访谈(n=16)进行了分析:记录显示,参加人数、坚持率、对手册的忠实度和成果完成率都很高。尽管有些人可能无法接受随机化,但招募似乎是可行的。尽管定量和定性数据都表明vCST是可接受的,但vCST和TAU在任何评估结果上都没有统计学差异,定性报告显示包括认知能力在内的结果都有所改善。在英国和全球的记忆服务机构中,CST 是针对痴呆症的主要社会心理干预措施;许多服务机构正在转向提供虚拟 CST。因此,对 vCST 的有效性进行全面的 RCT 试验是可行的,也是合理的。
{"title":"Virtual Group Cognitive Stimulation Therapy for Dementia: Mixed-Methods Feasibility Randomized Controlled Trial.","authors":"Aimee Spector, Nur Diyanah Abdul Wahab, Joshua Stott, Emily Fisher, Esther K Hui, Luke Perkins, Wing Gi Leung, Rachel Evans, Gloria Wong, Cerne Felstead","doi":"10.1093/geront/gnae063","DOIUrl":"10.1093/geront/gnae063","url":null,"abstract":"<p><strong>Background and objectives: </strong>Cognitive stimulation therapy (CST) is an evidence-based group intervention for people with dementia, with benefits for cognition and quality of life when delivered face-to-face. Many people are unable to attend face-to-face groups for reasons including health and transport issues. This study aimed to assess the feasibility and acceptability of online or \"virtual\" CST (vCST).</p><p><strong>Research design and methods: </strong>Single-blind, randomized controlled feasibility design with qualitative interviews. Forty-six people with mild-to-moderate dementia were randomly allocated to attend either 14 sessions of twice-weekly vCST (n = 24) or treatment as usual (TAU, defined as usual care; n = 22) over 7 weeks. Cognition, quality of life, and depression were assessed pre- and posttreatment. Qualitative interviews (n = 16) with participants and carers were analyzed using thematic analysis.</p><p><strong>Results: </strong>High levels of attendance, adherence, fidelity to the manual, and completion of outcomes were recorded. Recruitment appeared feasible although randomization may not have been acceptable to some. There were no statistical differences noted between vCST and TAU in any of the outcomes evaluated, although both quantitative and qualitative data indicated acceptability, with qualitative reports of improved outcomes including cognition.</p><p><strong>Discussion and implications: </strong>vCST appeared feasible to deliver but did not result in any changes in outcomes, as expected from an underpowered feasibility trial. CST is the main psychosocial intervention delivered for dementia in UK memory services and globally, with many services moving towards virtual CST delivery. Therefore, a fully powered RCT of the effectiveness of vCST is feasible and justified.</p>","PeriodicalId":51347,"journal":{"name":"Gerontologist","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11261826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141285377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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