Research in Developmental Disabilities最新文献

{"title":"Understanding sex/gender differences in intelligence profiles of children with Autism: A comprehensive WISC meta-analysis","authors":"David Giofrè ,&nbsp;Rachele Lievore ,&nbsp;Katie Allen ,&nbsp;Irene Tonizzi ,&nbsp;Irene Cristina Mammarella ,&nbsp;Enrico Toffalini","doi":"10.1016/j.ridd.2024.104854","DOIUrl":"10.1016/j.ridd.2024.104854","url":null,"abstract":"<div><h3>Background</h3><div>Intelligence assessment in children with autism spectrum disorders (ASD) often sparks debates about sex/gender differences. Specifically, the question arises whether girls exhibit lower performance on intelligence scales compared to boys. This meta-analysis examines nine studies (N=1105; 809 boys and 296 girls) to quantify sex/gender differences on the Wechsler Intelligence Scale for Children (WISC) in children with ASD, comparing their results to typically developing children.</div></div><div><h3>Method and procedures</h3><div>Random-effects meta-analyses on WISC indices and subtests were conducted to address the heterogeneity across effect sizes. Results for children with ASD were compared to those of typically developing children.</div></div><div><h3>Outcomes and results</h3><div>Findings revealed no significant differences in general intellectual functioning (full-scale IQ), verbal comprehension, working memory, or processing speed between boys and girls in children with ASD. Boys showed an advantage only in the perceptual reasoning index. At the subtest level, boys outperformed on certain tasks, while girls excelled in others.</div></div><div><h3>Conclusions and implications</h3><div>The observed pattern of differences in the ASD population aligns quantitatively with those in typically developing populations. Differences, if present, are specific to certain indices rather than general intelligence. These insights contribute to a nuanced understanding of gender-related cognitive variations in the context of ASD.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"154 ","pages":"Article 104854"},"PeriodicalIF":2.9,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vulnerability to depression and resolution in mothers of children with cerebral palsy","authors":"Tatjana Krstić ,&nbsp;Sanja Batić Očovaj ,&nbsp;Nina Brkić Jovanović ,&nbsp;Ljiljana Mihić","doi":"10.1016/j.ridd.2024.104852","DOIUrl":"10.1016/j.ridd.2024.104852","url":null,"abstract":"<div><h3>Background</h3><div>This study investigated associations between Self-Criticism and Dependency as factors of vulnerability to depression and maternal resolution. Resolution entails parental cognitive and emotional acceptance of the child's developmental disability.</div></div><div><h3>Methods</h3><div>Our sample included 100 mothers whose children had a diagnosis of cerebral palsy. The Reaction to Diagnosis Interview, the Depressive Experiences Questionnaire and the Depression Scale were administered.</div></div><div><h3>Results</h3><div>The results showed that unresolved mothers scored higher on the dimensions of Self-Criticism and Dependency compared to their resolved counterparts. The hierarchical cluster analysis yielded three maternal profiles based on the scores obtained on the dimensions of vulnerability to depression, regardless of maternal resolution status. The first profile was labeled Low Vulnerability and was characterized by low scores on Self-Criticism and Dependency. The second profile was labeled Dependent and it included mothers with higher scores on Dependency and lower scores on Self-Criticism. The third profile comprised mothers with higher scores on both Self-Criticism and Dependency. The smallest proportion of unresolved mothers belonged to the third, most vulnerable profile labeled Double Vulnerability.</div></div><div><h3>Discussion</h3><div>We discussed the implications of the obtained results in light of a need for psychotherapeutic interventions that would focus on individual differences when providing support to parental resolution.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"154 ","pages":"Article 104852"},"PeriodicalIF":2.9,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstacle negotiation while dual-tasking in children with Developmental Coordination Disorder (DCD): An augmented-reality approach","authors":"Emily Subara-Zukic ,&nbsp;Thomas B. McGuckian ,&nbsp;Michael H. Cole ,&nbsp;Peter Wilson","doi":"10.1016/j.ridd.2024.104853","DOIUrl":"10.1016/j.ridd.2024.104853","url":null,"abstract":"<div><h3>Background</h3><div>Children with Developmental Coordination Disorder (DCD) exhibit deficits in predictive motor control, balance, and aspects of cognitive control, which are important for safely negotiating obstacles while walking. As concurrent performance of cognitive and motor tasks (dual-tasking) may exacerbate these deficits, we examined motor and cognitive dual-tasking differences between children with DCD and their typically developing (TD) peers during obstacle negotiation.</div></div><div><h3>Methods</h3><div>34 children aged 6–12 years (16 TD, 18 DCD) walked along a 12 m path, stepping over an obstacle (30 % or 50 % of leg length) at its mid-point. On dual-task trials, participants completed a simple or complex (cognitive) visual discrimination task presented via an augmented reality headset. Proportional dual-task costs (pDTCs) were measured on cognitive and gait outcomes over three phases: pre-obstacle, obstacle step-over, and post-obstacle.</div></div><div><h3>Results</h3><div>During the obstacle step-over phase, both groups increased their leading leg clearance when dual-tasking, while the DCD group had larger pDTC than TD for the high obstacle under simple stimulus conditions (viz simple-high combination). The complex cognitive task produced larger pDTCs than the simple one on leading leg clearance and post-obstacle gait variability.</div></div><div><h3>Conclusions</h3><div>In general, both DCD and TD groups showed similar pDTCs under complex conditions, while the specific deficit in DCD under the simple-high combination suggests a (default) compensatory strategy during step-over when attention is diverted to a secondary task. Competing cognitive and motor demands during obstacle negotiation present a potential safety risk for children.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"154 ","pages":"Article 104853"},"PeriodicalIF":2.9,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DNA methylation signatures of prenatal socioeconomic position associated with 36-month language outcomes","authors":"Meghna Rajaprakash ,&nbsp;Meredith Palmore ,&nbsp;Kelly M. Bakulski ,&nbsp;Ellen Howerton ,&nbsp;Kristen Lyall ,&nbsp;Rebecca J. Schmidt ,&nbsp;Craig Newschaffer ,&nbsp;Lisa A. Croen ,&nbsp;Irva Hertz-Picciotto ,&nbsp;Heather Volk ,&nbsp;Christine Ladd-Acosta ,&nbsp;M. Daniele Fallin","doi":"10.1016/j.ridd.2024.104846","DOIUrl":"10.1016/j.ridd.2024.104846","url":null,"abstract":"<div><h3>Background</h3><div>Socioeconomic position (SEP), which reflects one’s position in society and access to resources, is strongly tied to neurodevelopment and is associated with epigenetic changes. AIM: This study examined whether DNA methylation signatures of prenatal SEP, measured in birth samples, are associated with child neurodevelopmental outcomes at 36 months of age. METHODS: Prenatal SEP DNA methylation scores were derived using 97 placenta and 127 cord blood biospecimens in the Early Autism Risk Longitudinal Investigation cohort. Participants completed the Mullen Scales of Early Learning (MSEL) and Vineland Adaptive Behavior Scales (VABS) at 36 months of age. Generalized regression analyses, adjusting for maternal age and race, were performed to test the association between SEP methylation score, for each birth biospecimen type, and MSEL and VABS scores. RESULTS: Significant associations were observed between placenta SEP methylation score and MSEL Expressive Language outcomes (beta = −2.7, p = 0.046, 95 % CI [- 5.43, −0.05]) and Receptive Language outcomes (beta = −2.5, p = 0.037, 95 % CI [-4.82, −0.16]). In cord blood, methylation-SEP scores were significantly associated with Receptive Language outcomes (beta = −2.0, p = 0.037, 95 % CI [-3.85, −0.12]). No significant associations were observed with VABS scores. CONCLUSION: Our results confirm associations between prenatal SEP and early childhood language development using a novel empiric DNA methylation measure of exposure</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"154 ","pages":"Article 104846"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How do fine and gross motor skills develop in preschool boys with Duchenne Muscular Dystrophy?","authors":"Jasmine Hoskens ,&nbsp;Ines Vandekerckhove ,&nbsp;Liesbeth De Waele ,&nbsp;Hilde Feys ,&nbsp;Nathalie Goemans ,&nbsp;Katrijn Klingels","doi":"10.1016/j.ridd.2024.104845","DOIUrl":"10.1016/j.ridd.2024.104845","url":null,"abstract":"<div><h3>Background</h3><div>Boys with Duchenne Muscular Dystrophy (DMD) experience both fine and gross motor problems. Nowadays, early intervention focuses almost exclusively on gross motor skills.</div></div><div><h3>Aims</h3><div>We aimed to explore early motor development in preschool boys with DMD and investigate the influence of cognition.</div></div><div><h3>Methods and procedures</h3><div>Seventeen boys with DMD (11 months- 6 years) were compared to typically developing (TD) peers and followed-up with the Bayley Scales of Infant and Toddler Development (Bayley-III); Peabody developmental motor scales (PDMS-II) and Motor Function Measure (MFM-20). The longitudinal evolution of fine and gross motor skills was investigated using linear mixed effect models (LMM). Cognition was added to the LMM as a covariate.</div></div><div><h3>Outcomes and results</h3><div>Preschool boys with DMD scored lower compared to TD peers on both fine and gross motor skills (p&lt;0.001). The evolution of motor development was subscale-dependent. A significant influence of cognition was found on different subscales (p= 0.002–0.04).</div></div><div><h3>Conclusions and implications</h3><div>Preschool boys with DMD do not achieve the same functioning level as TD boys. Cognition plays a crucial role in the evolution of motor skills. Our results suggest a shift to a broader psychomotor approach including both fine and gross motor skills, also considering the impact of cognition.</div></div><div><h3>What this paper adds?</h3><div>Our study provides a detailed mapping of early fine and gross motor development in preschool boys with Duchenne Muscular Dystrophy (DMD) and describes the influence of cognition on both fine and gross motor skills. Preschool boys with DMD do not achieve the same functioning level compared to typically developing boys. They score significantly lower on both fine and gross motor skills. The evolution of fine and gross motor development was subscale-dependent e.g. a negative-positive evolution was seen for grasping skills, with a tipping point around the age of four; stationary scaled scores decreased followed by a stabilization around the age four to five and locomotion scaled scores remained stable over time. Finally, we also found that cognition plays a crucial role in the evolution of both fine and gross motor skills. These new insights in the evolution of early motor development could be of added value for future clinical trials in young boys with DMD. Subsequently, increased alertness to early symptoms, e.g. developmental delay, may advance the age of diagnosis, as well as associated early intervention.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"154 ","pages":"Article 104845"},"PeriodicalIF":2.9,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142328309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do maternal and paternal education protect against developmental delays?","authors":"Diane L. Putnick ,&nbsp;Neil J. Perkins ,&nbsp;Edwina Yeung ,&nbsp;Shyamal D. Peddada","doi":"10.1016/j.ridd.2024.104848","DOIUrl":"10.1016/j.ridd.2024.104848","url":null,"abstract":"<div><h3>Background</h3><div>Parental education is linked to child development and wellbeing, but unique and combined contributions of maternal and paternal education have rarely been studied.</div></div><div><h3>Aims</h3><div>This study assessed the individual and joint associations of maternal and paternal education on children’s odds of a probable developmental delay.</div></div><div><h3>Methods and procedures</h3><div>Mothers (<em>N</em> = 3566) from the Upstate KIDS cohort study reported on theirs and the father’s highest level of education and completed the Ages and Stages Questionnaires up to 7 times when the child was 4- to 36-months-old. A nonparametric constrained inference technique assessed the association between education and probable developmental delays.</div></div><div><h3>Outcomes and results</h3><div>Higher levels of maternal and paternal education were protective against child probable developmental delays in years 2 (18, 24 months; <em>p</em>-trends&lt;.001) and 3 (30, 36 months; <em>p</em>-trends&lt;.001), but not year 1 (4, 8, 12 months; <em>p</em>-trend=.486–.832). Trends held adjusting for parental age and race. When adjusting for the other parent’s education, only maternal education had unique associations with delays. Among parents with the same or similar education levels, when both parents had one level higher education it was also protective.</div></div><div><h3>Conclusions and implications</h3><div>Both maternal and paternal education may protect against children’s developmental delays in toddlerhood, but maternal education may be particularly important.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"154 ","pages":"Article 104848"},"PeriodicalIF":2.9,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142323617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a combined neuropsychological and cognitive behavioral group therapy on young adults with Fragile X Syndrome: An explorative study","authors":"Federica Alice Maria Montanaro ,&nbsp;Paolo Alfieri ,&nbsp;Cristina Caciolo ,&nbsp;Giuseppina Spano ,&nbsp;Andrea Bosco ,&nbsp;Stefano Vicari","doi":"10.1016/j.ridd.2024.104839","DOIUrl":"10.1016/j.ridd.2024.104839","url":null,"abstract":"<div><h3>Background</h3><div>Fragile X Syndrome (FXS) is an X-linked neurodevelopmental disorder that leads to intellectual disability (ID) along with cognitive-behavioral difficulties. Research on psychosocial treatments in individuals FXS and ID is still lacking. This study aimed to investigate the effectiveness of a combined neuropsychological and cognitive behavioral group therapy (nCBT) among young adults with FXS.</div></div><div><h3>Method</h3><div>Ten young adults diagnosed with FXS took part in the second stage intervention of \"Corp-osa-Mente\" (CoM II), a group nCBT program previously outlined by Montanaro and colleagues in an earlier study, with the participants being the same as in the previous research. This report details the outcomes of an additional twelve-month group sections aimed at enhancing the ability to manage emotions and the socio-communicative skills of these young adults. Caregivers completed measures of adaptive functioning, emotional and behavior problems, executive function, communication skills and family quality of life at pre-treatment (T0) and post-treatment (T1).</div></div><div><h3>Results</h3><div>CoM II showed a decrease in depressive and anxiety symptoms from T0 to T1, along with increased socio-pragmatic and communication skills from pre-test to post-test intervention. Additionally, our analysis revealed improvements in the adapative behavior of participants and in the family quality of life.</div></div><div><h3>Conclusions</h3><div>These preliminary findings suggest that young adults with FXS and ID experienced positive outcomes through participation in CoM II, a group nCBT. However, it is recommended to undertake additional methodologically rigorous studies, such as randomized controlled trials (RCTs), to substantiate these initially promising findings.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"154 ","pages":"Article 104839"},"PeriodicalIF":2.9,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142323618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Negative emotions reduce sensorimotor cortex activity during proprioceptive modulation of rolandic ∼20HZ beta rhythm in typically developing children and those with neurodevelopmental conditions","authors":"Álvaro Sabater-Gárriz ,&nbsp;Francesc Mestre-Sansó ,&nbsp;Vicent Canals ,&nbsp;José Antonio Mingorance ,&nbsp;Pedro Montoya ,&nbsp;Inmaculada Riquelme","doi":"10.1016/j.ridd.2024.104842","DOIUrl":"10.1016/j.ridd.2024.104842","url":null,"abstract":"<div><h3>Background</h3><div>The Rolandic ∼20-Hz beta rhythm of the sensorimotor cortex is associated with motor function and perception. However, the modulation of this rhythm by different emotional stimuli is an innovative area of research.</div></div><div><h3>Aims</h3><div>This study aims at investigating the impact of affective pictures (positive, negative, and neutral) on the proprioceptive modulation of the Rolandic ∼20 Hz beta rhythm in typically developing children and children with neurodevelopmental disorders (i.e. cerebral palsy and autism).</div></div><div><h3>Methods and procedures</h3><div>EEG was recorded while participants experienced passive wrist movements during the simultaneous viewing of affective pictures. Time-frequency analysis of the sensorimotor oscillatory activity was performed.</div></div><div><h3>Outcomes and results</h3><div>Our findings revealed that pictures with negative emotional valence notably diminish event-related synchronization (ERS) amplitude during the perception of hand movement in all groups of children.</div></div><div><h3>Conclusions and implications</h3><div>These findings suggest that emotional stimuli, particularly the negative ones, could significantly influence brain's processing of proprioception, adding knowledge to the interaction of common comorbidities, such as sensorimotor disorders and emotional dysregulation, in children with neurodevelopmental disabilities.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"154 ","pages":"Article 104842"},"PeriodicalIF":2.9,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142318762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motor development trajectories of children with cerebral palsy in a community-based early intervention program in rural South India","authors":"Marie Brien ,&nbsp;Dinesh Krishna ,&nbsp;Ramasubramanian Ponnusamy ,&nbsp;Cathy Cameron ,&nbsp;Rahim Moineddin ,&nbsp;Franzina Coutinho","doi":"10.1016/j.ridd.2024.104829","DOIUrl":"10.1016/j.ridd.2024.104829","url":null,"abstract":"<div><h3>Background</h3><div>Developmental trajectories are crucial for evidence-based prognostication, planning interventions, and monitoring progress in children with cerebral palsy (CP).</div></div><div><h3>Aims</h3><div>To describe gross motor development patterns of children with CP in rural South India for the five Gross Motor Function Classification System (GMFCS) levels.</div></div><div><h3>Methods</h3><div>Longitudinal cohort study of 302 children (176 males, 126 females) with CP aged 0 to 10 years, followed by a community-based early intervention program. GMFCS levels were 5.4 % level 1, 16.5 % level II, 22.8 % level III, 26.8 % level IV, and 28.5 % level V. Assessments were undertaken using the Gross Motor Function Measure (GMFM-66) at 6-month intervals between April 2017 and August 2020. Longitudinal analyses were performed using mixed-effects linear regression models.</div></div><div><h3>Outcomes and results</h3><div>Five distinct motor development curves were created for ages 0 to 10 years by GMFCS levels as a function of age and GMFM-66 with a stable limit model, variation in estimated limits and rates of development.</div></div><div><h3>Conclusions and Implications</h3><div>Motor development trajectories for CP in an LMIC differ from those reported in HICs. Consideration of how social determinants of health, environmental and personal factors impact motor development in low-resource contexts is crucial. Further work is needed to describe developmental trajectories of children for CP in LMICs.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"154 ","pages":"Article 104829"},"PeriodicalIF":2.9,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0891422224001616/pdfft?md5=5034e5f9898d30514e04ff3c9a8d1bbc&pid=1-s2.0-S0891422224001616-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142315673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proxy- and self-report evaluation of quality of life in cerebral palsy: Using Spanish version of CPQOL for Children and adolescents","authors":"Alba Aza ,&nbsp;Inmaculada Riquelme ,&nbsp;María Gómez Vela ,&nbsp;Marta Badia","doi":"10.1016/j.ridd.2024.104844","DOIUrl":"10.1016/j.ridd.2024.104844","url":null,"abstract":"<div><h3>Background</h3><div>Promoting quality of life (QoL) is one of the main goals in interventions carried out with children and adolescents with cerebral palsy (CP).</div></div><div><h3>Aims</h3><div>The aim of this study was to analyze the determinants of QoL in children with CP, including evaluations by the children themselves and their parents, and to identify discrepancies between evaluators.</div></div><div><h3>Methods and procedures</h3><div>The adapted Spanish version of the Cerebral Palsy Quality of Life (CP-QOL) for children and adolescents (self-report and primary caregiver-reports versions) was applied to a sample of 74 children with CP and their respective parents (totaling 222 participants), as well as instruments to measure functioning (i.e., GMFCS, MACS, CFCS and EDACS). The average age of the children was 12.50 (<em>SD=</em>4.07), with a higher number of boys (55.7 %).</div></div><div><h3><em>Outcomes and results</em></h3><div>The lowest QoL levels were found in the Functional dimension in both assessments (<em>M</em>_{<em>children/adolescents</em>}=70.21, <em>M</em>_{<em>parents</em>}=58.14). For children, the highest rated dimension was Social Well-being (<em>M</em>=74.54), while for parents it was School (<em>M</em>=71.03). The degree of agreement between evaluators was low in almost all dimensions (ICC≤.40). More satisfactory predictive models were constructed from the evaluations carried out by parents, except in the case of the Access to Services dimension, with functioning measures being the main predictors of QoL levels.</div></div><div><h3>Conclusions and implications</h3><div>The CP-QOL in its two available versions is a useful and specific instrument for assessing QoL in children with CP in both research and professional fields.</div></div>","PeriodicalId":51351,"journal":{"name":"Research in Developmental Disabilities","volume":"154 ","pages":"Article 104844"},"PeriodicalIF":2.9,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0891422224001768/pdfft?md5=793c8eeeebb6ac460b7591d9768c38bd&pid=1-s2.0-S0891422224001768-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142315674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}