Pub Date : 2022-01-01DOI: 10.5114/hivar.2022.112756
Fábio Cardoso, C. G. Lima da Silva, Sávio Samuel Feitosa Machado, Sionara Melo Figueiredo de Carvalho, Modesto Leite Rolim Neto, Jaime Emanuel Brito Araújo
{"title":"Vaccination against COVID-19 and SARS-COV-2 in people living with HIV","authors":"Fábio Cardoso, C. G. Lima da Silva, Sávio Samuel Feitosa Machado, Sionara Melo Figueiredo de Carvalho, Modesto Leite Rolim Neto, Jaime Emanuel Brito Araújo","doi":"10.5114/hivar.2022.112756","DOIUrl":"https://doi.org/10.5114/hivar.2022.112756","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"21 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82655757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5114/hivar.2022.112580
I. Furtado, S. Valdoleiros, J. Fragoso, O. Vasconcelos, M. Gonçalves, R. Sarmento-Castro
{"title":"Clinical experience with dolutegravir: efficacy, safety, and tolerability","authors":"I. Furtado, S. Valdoleiros, J. Fragoso, O. Vasconcelos, M. Gonçalves, R. Sarmento-Castro","doi":"10.5114/hivar.2022.112580","DOIUrl":"https://doi.org/10.5114/hivar.2022.112580","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"24 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81612404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5114/hivar.2022.112682
Isabella Damiani, M. N. Naval Machado, Melissa Rodrigues de Araújo, Antônio Adilson Soares de Lima
{"title":"Primary syphilis as oral lesion in HIV/AIDS-positive patient: case report of unusual manifestation","authors":"Isabella Damiani, M. N. Naval Machado, Melissa Rodrigues de Araújo, Antônio Adilson Soares de Lima","doi":"10.5114/hivar.2022.112682","DOIUrl":"https://doi.org/10.5114/hivar.2022.112682","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"138 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80527228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5114/hivar.2022.112718
Rosa Nimmy Mathew, Manjula M.Y.
{"title":"Self-esteem and self-efficacy among HIV-positive adolescents: an intervention study","authors":"Rosa Nimmy Mathew, Manjula M.Y.","doi":"10.5114/hivar.2022.112718","DOIUrl":"https://doi.org/10.5114/hivar.2022.112718","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"241 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75917780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5114/hivar.2022.112758
B. Teshale, S. Awoke
Introduction: Acquired immune deficiency syndrome (AIDS) is a medical condition caused by human immunodeficiency virus (HIV), and has been the major concern worldwide. Despite antiretroviral treatment (ART) treatment showing significant clinical importance by meeting the goal of therapy, there is still a number of deaths due to socio-economic, demographic, and health-related factors. Therefore, this study was aimed to investigate the survival status and predictors of mortality for adult HIV-positive patients treated with ART. Material and methods: A retrospective cohort study was conducted with 1,285 of HIV-infected patients aged 15 years and greater, who were enrolled in ART at Mizan-Tepi University Teaching Hospital from September, 2007 to January, 2015. A multivariable Cox regression model was applied to assess significant predictors of mortality. Results: During follow-up period, a total of 1,285 patients contributed to 59,237 person/year of followup, and 273 (21%) of the patients died, showing overall incidence rate of 4.6 per 1,000 persons/ year (273/59,237). The median follow-up period was 44 months. During follow-up, 273 (21%) patients died, of whom nearly 32% and 12% of deaths occurred within 6 months and between 6 and 12 months of highly active antiretroviral therapy (HAART) initiation, respectively. Conclusions: Multivariable Cox proportional hazards model revealed that having concomitant tuberculosis infection, low baseline CD4 count, low baseline weight, living in rural area, using of a substance, older age, lower educational level, higher World Health Organization (WHO) clinical stages, functional status, and marital status were all significantly associated with progression to death for HIV/AIDS-infected patients. HIV AIDS Rev 2022; 21, 1: DOI: https://doi.org/10.5114/hivar.2022.112758
{"title":"Survival analysis and predictors of mortality for adult HIV/AIDS patients following antiretroviral therapy in Mizan-Tepi University Teaching Hospital, Southwest Ethiopia: a retrospective cohort study","authors":"B. Teshale, S. Awoke","doi":"10.5114/hivar.2022.112758","DOIUrl":"https://doi.org/10.5114/hivar.2022.112758","url":null,"abstract":"Introduction: Acquired immune deficiency syndrome (AIDS) is a medical condition caused by human immunodeficiency virus (HIV), and has been the major concern worldwide. Despite antiretroviral treatment (ART) treatment showing significant clinical importance by meeting the goal of therapy, there is still a number of deaths due to socio-economic, demographic, and health-related factors. Therefore, this study was aimed to investigate the survival status and predictors of mortality for adult HIV-positive patients treated with ART. Material and methods: A retrospective cohort study was conducted with 1,285 of HIV-infected patients aged 15 years and greater, who were enrolled in ART at Mizan-Tepi University Teaching Hospital from September, 2007 to January, 2015. A multivariable Cox regression model was applied to assess significant predictors of mortality. Results: During follow-up period, a total of 1,285 patients contributed to 59,237 person/year of followup, and 273 (21%) of the patients died, showing overall incidence rate of 4.6 per 1,000 persons/ year (273/59,237). The median follow-up period was 44 months. During follow-up, 273 (21%) patients died, of whom nearly 32% and 12% of deaths occurred within 6 months and between 6 and 12 months of highly active antiretroviral therapy (HAART) initiation, respectively. Conclusions: Multivariable Cox proportional hazards model revealed that having concomitant tuberculosis infection, low baseline CD4 count, low baseline weight, living in rural area, using of a substance, older age, lower educational level, higher World Health Organization (WHO) clinical stages, functional status, and marital status were all significantly associated with progression to death for HIV/AIDS-infected patients. HIV AIDS Rev 2022; 21, 1: DOI: https://doi.org/10.5114/hivar.2022.112758","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"55 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74362040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5114/hivar.2022.112762
Vikas Kumar, H. Joshi, I. Pandey
Human immunodeficiency virus (HIV) induces disease in humans that is known as AIDS (acquired immunodeficiency syndrome). First AIDS cases were registered in 1981, and later, types of HIV infection, such as HIV-1 and HIV-2 were identified. HIV belongs to class of retroviruses, known as ‘lenti-viruses’ and ‘slow’ viruses. A literature assessment was conducted through several reliable national and international journals as well as books and monographs, to investigate reverse transcriptase inhibitor (RI) from human immunodeficiency virus type 1 (HIV-1). Reverse transcriptase inhibitor limits the reverse transcriptase activity, which is considered the key enzyme of retroviral multiplication process, and eventually prevents infection and progression of retroviruses. In the current paper, more than twenty-five drugs were presented, which are used for management/treatment of AIDS. The aim of the present review was to summarize the latest update on reverse transcriptase inhibition. Lately, significant advancement has been observed on the growth of HIV-drugs targeting reverse transcriptase enzyme. There is a continuous increase in various compounds with anti-HIV activity and isolated from natural sources. The present review provided a selection of publications concerning the topic. Salient features of reverse transcriptase inhibitors (both NRTIs and NNRTI's) and possibility for development of new chemical entity were presented.
{"title":"Reverse transcriptase inhibition: a way to defeat HIV","authors":"Vikas Kumar, H. Joshi, I. Pandey","doi":"10.5114/hivar.2022.112762","DOIUrl":"https://doi.org/10.5114/hivar.2022.112762","url":null,"abstract":"Human immunodeficiency virus (HIV) induces disease in humans that is known as AIDS (acquired immunodeficiency syndrome). First AIDS cases were registered in 1981, and later, types of HIV infection, such as HIV-1 and HIV-2 were identified. HIV belongs to class of retroviruses, known as ‘lenti-viruses’ and ‘slow’ viruses. A literature assessment was conducted through several reliable national and international journals as well as books and monographs, to investigate reverse transcriptase inhibitor (RI) from human immunodeficiency virus type 1 (HIV-1). Reverse transcriptase inhibitor limits the reverse transcriptase activity, which is considered the key enzyme of retroviral multiplication process, and eventually prevents infection and progression of retroviruses. In the current paper, more than twenty-five drugs were presented, which are used for management/treatment of AIDS. The aim of the present review was to summarize the latest update on reverse transcriptase inhibition. Lately, significant advancement has been observed on the growth of HIV-drugs targeting reverse transcriptase enzyme. There is a continuous increase in various compounds with anti-HIV activity and isolated from natural sources. The present review provided a selection of publications concerning the topic. Salient features of reverse transcriptase inhibitors (both NRTIs and NNRTI's) and possibility for development of new chemical entity were presented.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"77 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80150521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5114/hivar.2022.113389
R. Safdari, Seyedahmad Seyedalinaghi, N. Mohammadzadeh, T. Noori, Pakzad Rahmati, Kowsar Qaderi, F. Voltarelli, E. Mehraeen
{"title":"Developing Aysoo: a mobile-based self-management application for people living with HIV","authors":"R. Safdari, Seyedahmad Seyedalinaghi, N. Mohammadzadeh, T. Noori, Pakzad Rahmati, Kowsar Qaderi, F. Voltarelli, E. Mehraeen","doi":"10.5114/hivar.2022.113389","DOIUrl":"https://doi.org/10.5114/hivar.2022.113389","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"162 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73127657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.5114/hivar.2022.112852
Minyechil Alehegn
{"title":"Application of machine learning and deep learning for the prediction of HIV/AIDS","authors":"Minyechil Alehegn","doi":"10.5114/hivar.2022.112852","DOIUrl":"https://doi.org/10.5114/hivar.2022.112852","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"14 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82283366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5114/hivar.2021.111544
Fatemeh Shamsolahi, S. Mirmolaei, A. Kasaeian, H. Ranjbar, M. Modarres
Introduction: Sexually transmitted diseases (STDs) are among the most common infectious diseases in women. The aim of the present study was to determine the effect of teaching based on theory of planned behavior on preventive behaviors of STDs of married women. Material and methods: Study subjects consisted of 114 women who attended a university-affiliated hospital in Tehran, Iran. They were randomly assigned into intervention group (n = 58) and control group (n = 56). Women in intervention group participated in a four-session educational program based on a theory of planned behavior. Women in control group received a routine education. Data-gathering tool was a researcher-made questionnaire, including demographic characteristics, knowledge on sexually transmitted diseases, attitude, subjective norms, perceived behavioral control, and intention for healthy behavior along with self-reported sexual behaviors. Data was analyzed using repeated measure ANOVA. Results: All constructs of the theory of planned behavior along with the knowledge and reported sexual behaviors improved significantly in intervention group in comparison to controls. The theory of planned behavior was effective in the increase of knowledge and improvement of attitude, subjective norms, perceived behavioral control, and intention for healthy behaviors in married women. It was also effective in improving healthier sexual behaviors. Conclusions: Education program based on the theory of planned behavior was effective on preventive behaviors of STDs of married women. We recommend using this theory in prevention programs for sexually transmitted diseases in married women. HIV AIDS Rev 2021; 20, 4: 294-301 DOI: https://doi.org/10.5114/hivar.2021.111544
导言:性传播疾病是妇女最常见的传染病之一。本研究旨在探讨计划行为理论教学对已婚妇女性病预防行为的影响。材料和方法:研究对象包括114名在伊朗德黑兰一所大学附属医院就诊的女性。随机分为干预组(n = 58)和对照组(n = 56)。干预组的妇女参加了一个以计划行为理论为基础的四期教育项目。对照组妇女接受常规教育。数据收集工具是一份调查问卷，包括人口统计特征、性传播疾病知识、态度、主观规范、感知行为控制、健康行为意愿以及自我报告的性行为。数据分析采用重复测量方差分析。结果:干预组计划行为理论的各项构念、性行为知识和性行为报告均较对照组有显著提高。计划行为理论对提高已婚妇女对健康行为的认识和态度、主观规范、感知行为控制、意愿等方面的改善有较好的效果。它在改善健康的性行为方面也很有效。结论:以计划行为理论为基础的教育对已婚妇女性病预防行为有较好的效果。我们建议在已婚妇女的性传播疾病预防项目中使用这一理论。HIV / AIDS Rev 2021;DOI: https://doi.org/10.5114/hivar.2021.111544
{"title":"Effect of educational program based on planned behavior theory on preventive behaviors of sexually transmitted diseases of married women","authors":"Fatemeh Shamsolahi, S. Mirmolaei, A. Kasaeian, H. Ranjbar, M. Modarres","doi":"10.5114/hivar.2021.111544","DOIUrl":"https://doi.org/10.5114/hivar.2021.111544","url":null,"abstract":"Introduction: Sexually transmitted diseases (STDs) are among the most common infectious diseases in women. The aim of the present study was to determine the effect of teaching based on theory of planned behavior on preventive behaviors of STDs of married women. Material and methods: Study subjects consisted of 114 women who attended a university-affiliated hospital in Tehran, Iran. They were randomly assigned into intervention group (n = 58) and control group (n = 56). Women in intervention group participated in a four-session educational program based on a theory of planned behavior. Women in control group received a routine education. Data-gathering tool was a researcher-made questionnaire, including demographic characteristics, knowledge on sexually transmitted diseases, attitude, subjective norms, perceived behavioral control, and intention for healthy behavior along with self-reported sexual behaviors. Data was analyzed using repeated measure ANOVA. Results: All constructs of the theory of planned behavior along with the knowledge and reported sexual behaviors improved significantly in intervention group in comparison to controls. The theory of planned behavior was effective in the increase of knowledge and improvement of attitude, subjective norms, perceived behavioral control, and intention for healthy behaviors in married women. It was also effective in improving healthier sexual behaviors. Conclusions: Education program based on the theory of planned behavior was effective on preventive behaviors of STDs of married women. We recommend using this theory in prevention programs for sexually transmitted diseases in married women. HIV AIDS Rev 2021; 20, 4: 294-301 DOI: https://doi.org/10.5114/hivar.2021.111544","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"83 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88430196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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