Pub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.105050
P. Achdiat, Rasmia Rowawi, H. Gunawan, O. Suwarsa, Catherina Jessica Sutantoyo
Patients with human immunodeficiency virus (HIV) disease are more likely to develop anogenital warts (AGW) compared to HIV-negative people, and are susceptible to treatment failures and illness recurrences. Glycyrrhizinic acid (GA) is extracted from licorice root (Glycyrrhiza glabra). Previous studies have demonstrated the efficacy of GA 0.1% spray as a treatment for external AGW, but its role in immunocompromised patients has not been explored. The current study reported two cases of HIV-positive patients with AGW who experienced partial remission using GA 0.1% spray. The treatment was applied by the patients three times a day for eight weeks. Treatment evaluation were made by using visual inspection and dermoscopy image analysis. After twelve weeks, clinical observation revealed poor improvement with only slight reduction in number and size of the lesions; although dermoscopy findings revealed an evolution from finger-like to knob-like pattern. GA facilitate the development of T helper lymphocytes in cell-mediated immune response, whereas in HIV, there are a decreased number of T helper lymphocytes. This may explain poor therapeutic response in our patient. Dermoscope is useful in the evaluation of treatment progress, especially when invisible to unaided eye. HIV AIDS Rev 2021; 20, 1: 65-69 DOI: https://doi.org/10.5114/hivar.2021.105050
与艾滋病毒阴性的人相比，患有人类免疫缺陷病毒(HIV)疾病的患者更容易发生肛门生殖器疣(AGW)，并且容易受到治疗失败和疾病复发的影响。甘草酸(GA)是从甘草根(glycyrhiza glabra)中提取的。先前的研究已经证明了0.1% GA喷雾治疗外源性AGW的有效性，但其在免疫功能低下患者中的作用尚未探讨。目前的研究报告了两例hiv阳性的AGW患者，他们使用0.1%的GA喷雾剂获得了部分缓解。患者每天进行三次治疗，持续八周。采用目视检查和皮肤镜图像分析对治疗效果进行评价。12周后，临床观察显示改善不佳，仅病变数量和大小略有减少;虽然皮肤镜检查结果显示从手指样到旋钮样的演变。GA在细胞介导的免疫应答中促进T辅助淋巴细胞的发育，而在HIV中，T辅助淋巴细胞的数量减少。这也许可以解释我们的病人治疗反应差的原因。皮肤镜在评估治疗进展方面是有用的，特别是当肉眼看不见时。HIV / AIDS Rev 2021;DOI: https://doi.org/10.5114/hivar.2021.105050
{"title":"Clinical dermatoscopical response of glycyrrhizinic acid 0.1% spray in treating external anogenital warts in HIV patients: a case series","authors":"P. Achdiat, Rasmia Rowawi, H. Gunawan, O. Suwarsa, Catherina Jessica Sutantoyo","doi":"10.5114/HIVAR.2021.105050","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.105050","url":null,"abstract":"Patients with human immunodeficiency virus (HIV) disease are more likely to develop anogenital warts (AGW) compared to HIV-negative people, and are susceptible to treatment failures and illness recurrences. Glycyrrhizinic acid (GA) is extracted from licorice root (Glycyrrhiza glabra). Previous studies have demonstrated the efficacy of GA 0.1% spray as a treatment for external AGW, but its role in immunocompromised patients has not been explored. The current study reported two cases of HIV-positive patients with AGW who experienced partial remission using GA 0.1% spray. The treatment was applied by the patients three times a day for eight weeks. Treatment evaluation were made by using visual inspection and dermoscopy image analysis. After twelve weeks, clinical observation revealed poor improvement with only slight reduction in number and size of the lesions; although dermoscopy findings revealed an evolution from finger-like to knob-like pattern. GA facilitate the development of T helper lymphocytes in cell-mediated immune response, whereas in HIV, there are a decreased number of T helper lymphocytes. This may explain poor therapeutic response in our patient. Dermoscope is useful in the evaluation of treatment progress, especially when invisible to unaided eye. HIV AIDS Rev 2021; 20, 1: 65-69 DOI: https://doi.org/10.5114/hivar.2021.105050","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"20 1","pages":"65-69"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71091520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5114/hivar.2021.111536
T. Mikuła, Dagny C. Krankowska, A. Wiercińska-Drapało
Sepsis is one of the major causes of mortality of patients worldwide, and patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) are at higher risk of developing it. Given the importance of quick diagnosis, the demand for sepsis biomarkers is high. In this article, the authors reviewed the available sepsis biomarkers, and assessed whether the biomarkers were analyzed in patients with HIV/AIDS. We investigated the available literature on classic inflammatory biomarkers, such as procalcitonin (PCT) and interleukin-6 (IL-6) as well as new biomarkers of sepsis, including soluble form of urokinase-type plasminogen activator receptor (suPAR), proadrenomedullin (proADM), soluble triggering receptor expressed on myeloid cells 1 (sTREM-1), growth arrest-specific 6 (Gas6), and microRNA (miRNA) in immunocompetent patients and patients living with HIV/AIDS. Various biomarkers have a diagnostic value (PCT, sTREM-1), others present a prognostic value (suPAR, Gas6, PSP, HBP), and some biomarkers have both values (IL-6, proADM, sCD14-ST, miRNA). Combining at least two different biomarkers has the best potential to bring high sensitivity and specificity of diagnosis. To our knowledge, many of discussed novel inflammatory biomarkers, such as presepsin, pancreatic stone protein/regenerating protein (PSP/reg), or heparin-binding protein (HBP), were not yet studied in a population of patients with HIV/AIDS and sepsis. of sepsis. Monitoring at least two biomarkers might increase the chance of early detection of sepsis. Further research is needed to find biomarkers diagnosing sepsis in patients with AIDS.
{"title":"The newest and classic biomarkers of sepsis in HIV-infected adult patients","authors":"T. Mikuła, Dagny C. Krankowska, A. Wiercińska-Drapało","doi":"10.5114/hivar.2021.111536","DOIUrl":"https://doi.org/10.5114/hivar.2021.111536","url":null,"abstract":"Sepsis is one of the major causes of mortality of patients worldwide, and patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) are at higher risk of developing it. Given the importance of quick diagnosis, the demand for sepsis biomarkers is high. In this article, the authors reviewed the available sepsis biomarkers, and assessed whether the biomarkers were analyzed in patients with HIV/AIDS. We investigated the available literature on classic inflammatory biomarkers, such as procalcitonin (PCT) and interleukin-6 (IL-6) as well as new biomarkers of sepsis, including soluble form of urokinase-type plasminogen activator receptor (suPAR), proadrenomedullin (proADM), soluble triggering receptor expressed on myeloid cells 1 (sTREM-1), growth arrest-specific 6 (Gas6), and microRNA (miRNA) in immunocompetent patients and patients living with HIV/AIDS. Various biomarkers have a diagnostic value (PCT, sTREM-1), others present a prognostic value (suPAR, Gas6, PSP, HBP), and some biomarkers have both values (IL-6, proADM, sCD14-ST, miRNA). Combining at least two different biomarkers has the best potential to bring high sensitivity and specificity of diagnosis. To our knowledge, many of discussed novel inflammatory biomarkers, such as presepsin, pancreatic stone protein/regenerating protein (PSP/reg), or heparin-binding protein (HBP), were not yet studied in a population of patients with HIV/AIDS and sepsis. of sepsis. Monitoring at least two biomarkers might increase the chance of early detection of sepsis. Further research is needed to find biomarkers diagnosing sepsis in patients with AIDS.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"242 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80526169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.107238
A. Obadeji, L. Oluwole, B. Kumolalo, A. S. Ajiboye
{"title":"Psychological well-being and gender difference in alcohol and substance use among people living with HIV/AIDS","authors":"A. Obadeji, L. Oluwole, B. Kumolalo, A. S. Ajiboye","doi":"10.5114/HIVAR.2021.107238","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.107238","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"95 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76914846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5114/hivar.2021.111395
Etsay Woldu Anbesu, Aydahis Ali Mohammed
Introduction: Human immune deficiency virus (HIV)-infected individuals experience significant implications in terms of having children due to transmission of human immune deficiency. However, fertility desire has given little attention, and the uptake of prevention of mother-to-child transmission services is low in Ethiopia, particularly in Afar region. Thus, this study aimed to assess fertility desire and associated factors among human immune virus-positive women attending ART clinics. Material and methods: An institution-based cross-sectional study was conducted with 402 HIV-positive women attending anti-retroviral therapy clinics in selected hospitals of Afar region. Logistic regression analysis was employed to identify factors associated with fertility desire. Statistical association was measured, with a p-value < 0.05 considered statistically significant. Results: The prevalence of fertility desire was 63.9% (95% CI: 59.1-68.8%). Young ages women, i.e., 15-24 years (AOR = 11.98; 95% CI: 4.04-35.5) and 25-34 years (AOR = 2.93, 95% CI: 1.46-5.86), who did not have living children (AOR = 5.1; 95% CI: 1.31-20.2) and women with 1 or 2 children alive (AOR = 2.7; 95% CI: 1.39-5.27), and disclosed sero-status (AOR = 5.89; 95% CI: 2.33-14.9) were associated with increased odds of fertility desire. However, contraceptives use was associated with decreased odds of fertility desire (AOR = 0.11; 95% CI: 0.05-0.22). Conclusions: In this study, six in ten study subjects had fertility desires. Young age, not having living child, having 1 or 2 children alive, disclosing sero-status to partner, and contraceptive use were predictors for fertility desire. HIV AIDS Rev 2021; 20, 4: 281-286 DOI: https://doi.org/10.5114/hivar.2021.111395
{"title":"Fertility desire and associated factors among HIV-positive women attending ART clinics in Afar region, Northeast Ethiopia","authors":"Etsay Woldu Anbesu, Aydahis Ali Mohammed","doi":"10.5114/hivar.2021.111395","DOIUrl":"https://doi.org/10.5114/hivar.2021.111395","url":null,"abstract":"Introduction: Human immune deficiency virus (HIV)-infected individuals experience significant implications in terms of having children due to transmission of human immune deficiency. However, fertility desire has given little attention, and the uptake of prevention of mother-to-child transmission services is low in Ethiopia, particularly in Afar region. Thus, this study aimed to assess fertility desire and associated factors among human immune virus-positive women attending ART clinics. Material and methods: An institution-based cross-sectional study was conducted with 402 HIV-positive women attending anti-retroviral therapy clinics in selected hospitals of Afar region. Logistic regression analysis was employed to identify factors associated with fertility desire. Statistical association was measured, with a p-value < 0.05 considered statistically significant. Results: The prevalence of fertility desire was 63.9% (95% CI: 59.1-68.8%). Young ages women, i.e., 15-24 years (AOR = 11.98; 95% CI: 4.04-35.5) and 25-34 years (AOR = 2.93, 95% CI: 1.46-5.86), who did not have living children (AOR = 5.1; 95% CI: 1.31-20.2) and women with 1 or 2 children alive (AOR = 2.7; 95% CI: 1.39-5.27), and disclosed sero-status (AOR = 5.89; 95% CI: 2.33-14.9) were associated with increased odds of fertility desire. However, contraceptives use was associated with decreased odds of fertility desire (AOR = 0.11; 95% CI: 0.05-0.22). Conclusions: In this study, six in ten study subjects had fertility desires. Young age, not having living child, having 1 or 2 children alive, disclosing sero-status to partner, and contraceptive use were predictors for fertility desire. HIV AIDS Rev 2021; 20, 4: 281-286 DOI: https://doi.org/10.5114/hivar.2021.111395","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"118 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85349790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.107239
J. Akinyemi, O. Eniade, R. Afolabi, O. Awolude
{"title":"Partner’s profile and unmet need for child limiting among women living with HIV in Ibadan, Nigeria","authors":"J. Akinyemi, O. Eniade, R. Afolabi, O. Awolude","doi":"10.5114/HIVAR.2021.107239","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.107239","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"39 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89226347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.105106
L. Karimi, F. Rahmati, A. Parandeh
Introduction: Worldwide, sexually transmitted diseases and acquired immunodeficiency syndrome (AIDS) are major health issues. Sexual health literacy refers to a range of sexual health literacy that encompasses a variety of areas, including gender and sexual development, puberty, pregnancy, contraceptive methods, unwanted pregnancy, and sexually transmitted diseases. The evaluation of sexual health literacy needs an appropriate tool. The aim of this study was to develop and evaluate psychometric properties of an instrument to measure sexual health literacy related to AIDS and sexually transmitted diseases among young Iranian men between the ages of 19 to 29 years old. Material and methods: This study was carried in out two phases in Tehran during 2018-2019. In the first phase, a questionnaire was developed by item generation through an expert panel and literature review. In the second part, an assessment of psychometric properties of questionnaire, including face and content validity, was performed. Reliability of questionnaire was assessed using internal consistency (Cronbach’s a) and interclass correlation coefficient (ICC). Results: The content validity indices (CVI and CVR) for all items were 0.89 and 0.87, respectively. The designed tool showed a high internal consistency reliability, with Cronbach’s a ranging from 0.79 to 0.87 and ICC ranging from 0.79 to 0.87. Conclusions: The psychometric assessment of the 30-item questionnaire indicates desirable validity and reliability. This questionnaire is recommended for assessing the level of sexual health literacy of young men in future studies. HIV AIDS Rev 2021; 20, 1: 26-32 DOI: https://doi.org/10.5114/hivar.2021.105106
{"title":"Development and validation of psychometric properties of a questionnaire for sexual health literacy related to HIV/AIDS and sexually transmitted diseases among Iranian young men","authors":"L. Karimi, F. Rahmati, A. Parandeh","doi":"10.5114/HIVAR.2021.105106","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.105106","url":null,"abstract":"Introduction: Worldwide, sexually transmitted diseases and acquired immunodeficiency syndrome (AIDS) are major health issues. Sexual health literacy refers to a range of sexual health literacy that encompasses a variety of areas, including gender and sexual development, puberty, pregnancy, contraceptive methods, unwanted pregnancy, and sexually transmitted diseases. The evaluation of sexual health literacy needs an appropriate tool. The aim of this study was to develop and evaluate psychometric properties of an instrument to measure sexual health literacy related to AIDS and sexually transmitted diseases among young Iranian men between the ages of 19 to 29 years old. Material and methods: This study was carried in out two phases in Tehran during 2018-2019. In the first phase, a questionnaire was developed by item generation through an expert panel and literature review. In the second part, an assessment of psychometric properties of questionnaire, including face and content validity, was performed. Reliability of questionnaire was assessed using internal consistency (Cronbach’s a) and interclass correlation coefficient (ICC). Results: The content validity indices (CVI and CVR) for all items were 0.89 and 0.87, respectively. The designed tool showed a high internal consistency reliability, with Cronbach’s a ranging from 0.79 to 0.87 and ICC ranging from 0.79 to 0.87. Conclusions: The psychometric assessment of the 30-item questionnaire indicates desirable validity and reliability. This questionnaire is recommended for assessing the level of sexual health literacy of young men in future studies. HIV AIDS Rev 2021; 20, 1: 26-32 DOI: https://doi.org/10.5114/hivar.2021.105106","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91329739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.107217
Tantut Susanto, R. Yunanto, Hanny Rasni, Latifa Aini Susumaningrum
{"title":"Multi-level intervention for HIV/AIDS caring in Indonesian community","authors":"Tantut Susanto, R. Yunanto, Hanny Rasni, Latifa Aini Susumaningrum","doi":"10.5114/HIVAR.2021.107217","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.107217","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"19 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73008251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.107218
D. Aluh, Obinna C. Anyachebelu, A. Isah
{"title":"Depression literacy among people living with HIV/AIDS in a Nigerian tertiary hospital","authors":"D. Aluh, Obinna C. Anyachebelu, A. Isah","doi":"10.5114/HIVAR.2021.107218","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.107218","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"35 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90991120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.105087
A. Doat, E. Navab, A. Hoseini
Introduction: Adolescents living with human immunodeficiency virus (HIV) in sub-Saharan Africa continue to experience extreme health vulnerabilities. Children with HIV may experience major physiological problems. This study explored the experience of Ghanaian adolescents with HIV. Material and methods: Semi-structured interviews were used to collect data. 12 adolescents living with HIV between the ages of 14 to 19 years were recruited. Since a physiological problem is not without some level of emotional consequence, the most appropriate method to explore these physiological and emotional dimensions of treatment and diseases are through a qualitative research method. Results: Two main themes emerged from this study: ‘Rhapsody of physiological burden’ and ‘Bittersweet experience of adjusting to antiretroviral therapy (ART)’. Participants reported experiencing challenges, including bouts of headaches, itchy skin rashes, general body weakness, vomiting, appetite loss, diarrhea, and many more. Adolescents reported varying accounts concerning ART. Some patients described positive image of treatment, while others reported traumatic ordeal regarding side effects of the treatment to the extent that some stopped taking their medications. Conclusions: Policies aimed at supporting adolescents living with HIV needs to consider their unique set of physiological challenges to help improve health outcomes of the youngsters. Nurses should inform patients about results as well as possible side effects of ART prior initiation of the regimen, and also explain adverse events, which should be reported to hospital. concepts,
{"title":"Paradoxical experiences of Ghanaian adolescents with HIV: physiological challenges","authors":"A. Doat, E. Navab, A. Hoseini","doi":"10.5114/HIVAR.2021.105087","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.105087","url":null,"abstract":"Introduction: Adolescents living with human immunodeficiency virus (HIV) in sub-Saharan Africa continue to experience extreme health vulnerabilities. Children with HIV may experience major physiological problems. This study explored the experience of Ghanaian adolescents with HIV. Material and methods: Semi-structured interviews were used to collect data. 12 adolescents living with HIV between the ages of 14 to 19 years were recruited. Since a physiological problem is not without some level of emotional consequence, the most appropriate method to explore these physiological and emotional dimensions of treatment and diseases are through a qualitative research method. Results: Two main themes emerged from this study: ‘Rhapsody of physiological burden’ and ‘Bittersweet experience of adjusting to antiretroviral therapy (ART)’. Participants reported experiencing challenges, including bouts of headaches, itchy skin rashes, general body weakness, vomiting, appetite loss, diarrhea, and many more. Adolescents reported varying accounts concerning ART. Some patients described positive image of treatment, while others reported traumatic ordeal regarding side effects of the treatment to the extent that some stopped taking their medications. Conclusions: Policies aimed at supporting adolescents living with HIV needs to consider their unique set of physiological challenges to help improve health outcomes of the youngsters. Nurses should inform patients about results as well as possible side effects of ART prior initiation of the regimen, and also explain adverse events, which should be reported to hospital. concepts,","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"27 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91334668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.5114/hivar.2021.108786
Susana Barradas, C. Finck
Introduction: Human immunodeficiency virus (HIV) epidemic is one of the main problems in public health, and health-related quality of life (HRQoL) is usually negatively affected. Stigma is one of the factors related to a lower HRQoL. Material and methods: We aimed to assess this relationship, and felt stigma was measured using HIV felt stigma scale, while HRQoL was measured with EORTC QLQ-C30. We interviewed 140 patients, and 10.9% of our respondents reported feeling severe stigma, 25.4% moderate stigma, 26.1% mild stigma, and 37.7% absence of stigma. Results: Average score for overall HRQoL was 83.3 (SD = 21.4). Higher levels of stigma were associated with lower levels of perceived global HRQoL (β = –0.32, p = 0.001). Moreover, higher levels of stigma were correlated with a lower physical function (β = –0.27, p = 0.005), role function (β = –0.28, p = 0.001), cognitive function (β = –0.30, p = 0.001), social function (β = –0.32, p = 0.001), and emotional function (β = –0.60, p < 0.001). Conclusions: Reducing felt stigma could help improve HRQoL in HIV-positive patients.
人类免疫缺陷病毒(HIV)的流行是公共卫生的主要问题之一，与健康相关的生活质量(HRQoL)通常受到负面影响。耻辱感是与较低HRQoL相关的因素之一。材料和方法:我们旨在评估这种关系，使用HIV感觉耻辱量表测量感觉耻辱，HRQoL用EORTC QLQ-C30测量。我们采访了140名患者，10.9%的受访者表示有严重的耻辱感，25.4%的人有中度的耻辱感，26.1%的人有轻度的耻辱感，37.7%的人没有耻辱感。结果:总HRQoL平均得分为83.3分(SD = 21.4)。较高的耻辱感水平与较低的感知总体HRQoL水平相关(β = -0.32, p = 0.001)。此外，较高的耻辱感水平与较低的身体功能(β = -0.27, p = 0.005)、角色功能(β = -0.28, p = 0.001)、认知功能(β = -0.30, p = 0.001)、社会功能(β = -0.32, p = 0.001)和情绪功能(β = -0.60, p < 0.001)相关。结论:减少耻辱感有助于改善hiv阳性患者的HRQoL。
{"title":"Relationship between stigma and health-related quality of life in patients diagnosed with HIV","authors":"Susana Barradas, C. Finck","doi":"10.5114/hivar.2021.108786","DOIUrl":"https://doi.org/10.5114/hivar.2021.108786","url":null,"abstract":"Introduction: Human immunodeficiency virus (HIV) epidemic is one of the main problems in public health, and health-related quality of life (HRQoL) is usually negatively affected. Stigma is one of the factors related to a lower HRQoL. Material and methods: We aimed to assess this relationship, and felt stigma was measured using HIV felt stigma scale, while HRQoL was measured with EORTC QLQ-C30. We interviewed 140 patients, and 10.9% of our respondents reported feeling severe stigma, 25.4% moderate stigma, 26.1% mild stigma, and 37.7% absence of stigma. Results: Average score for overall HRQoL was 83.3 (SD = 21.4). Higher levels of stigma were associated with lower levels of perceived global HRQoL (β = –0.32, p = 0.001). Moreover, higher levels of stigma were correlated with a lower physical function (β = –0.27, p = 0.005), role function (β = –0.28, p = 0.001), cognitive function (β = –0.30, p = 0.001), social function (β = –0.32, p = 0.001), and emotional function (β = –0.60, p < 0.001). Conclusions: Reducing felt stigma could help improve HRQoL in HIV-positive patients.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"52 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84817443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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