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Molecular communication data augmentation and deep learning based detection 分子通讯数据扩增和基于深度学习的检测
IF 2.9 4区 计算机科学 Q1 Mathematics Pub Date : 2024-04-24 DOI: 10.1016/j.nancom.2024.100510
Davide Scazzoli , Fardad Vakilipoor , Maurizio Magarini

This manuscript presents a novel model for generating synthetic data for a biological molecular communication (MC) system to train a Neural Network (NN) for the purpose of discriminating transmitted bits. To achieve this, a deep learning algorithm was trained using the synthetic data and tested against experimentally measured data. The polynomial curve fitting coefficients are chosen as features. The featurization stage is followed by a NN that captures different aspects of the temporal correlation of the received signals. The real data was collected from an MC testbed that employed transfected Escherichia coli (E. coli) bacteria expressing the light-driven proton pump gloeorhodopsin from Gloeobacter violaceus. By stimulating the bacteria with externally controlled light, protons were secreted, which changed the pH level of the environment. A pH detector was then used to measure the pH of the environment. We propose the use of a deep convolutional neural network to detect the transmitted bits. This paper discusses the data augmentation, processing, and NNs that are pertinent to practical MC problems. The trained algorithm demonstrated an accuracy of over 99.9% in detecting transmitted bits from received signals at a bit rate of 1 bit/min, without requiring any specific knowledge of the underlying channel.

本手稿提出了一种新模型,用于生成生物分子通信(MC)系统的合成数据,以训练神经网络(NN),达到分辨传输比特的目的。为此,使用合成数据训练了深度学习算法,并根据实验测量数据进行了测试。多项式曲线拟合系数被选为特征。在特征化阶段之后是捕捉接收信号时间相关性不同方面的 NN。真实数据是从 MC 测试平台上收集的,该测试平台采用了转染大肠杆菌(E. coli),该细菌表达了来自 Gloeobacter violaceus 的光驱动质子泵 gloeorhodopsin。通过外部控制的光刺激细菌,质子被分泌出来,从而改变了环境的 pH 值。然后使用 pH 检测器测量环境的 pH 值。我们建议使用深度卷积神经网络来检测传输的比特。本文讨论了与实际 MC 问题相关的数据增强、处理和神经网络。经过训练的算法显示,在比特率为 1 比特/分钟的情况下,从接收信号中检测传输比特的准确率超过 99.9%,而不需要对底层信道有任何具体了解。
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引用次数: 0
A fault-tolerant QCA-based convolution encoder for robust data transmission 基于 QCA 的容错卷积编码器用于稳健的数据传输
IF 2.9 4区 计算机科学 Q1 Mathematics Pub Date : 2024-04-24 DOI: 10.1016/j.nancom.2024.100507
Utkarsh Vaish, Jeswin Sam Abraham, Vobulapuram Ramesh Kumar

Metal oxide semiconductor (MOS) technology has reached its maximum profitable limits due to increase in leakage current, static power dissipation, limited switching frequency. One of the better solutions to overcome these problems is the quantum-dot cellular automata (QCA) technology, it boasts the absence of physical transportation charges, relying solely on Coulombic force for interaction between the cells also it is a transistor less technology does not require any external voltage bias. In the current integrated circuits, the data being transferred more than ever, the error correction and coding techniques find significance in reliable data communication. Recognizing the increasing importance of error correction in data communication, particularly with the widespread data transfer, this research specifically focuses on the implementation of an enhanced convolutional encoder using QCA for error correction in data transmission. Comparative study with the state-of-art is also carried out to examine performance of proposed design. As a result of our study, we were able to reduce the cell count by 33.34% and power dissipation is reduced by 77% with the proposed 1/2 rate encoder and the proposed 1/3 rate encoder has 15.9% less cell count and power dissipation is reduced by 72% as compared to existing design.

金属氧化物半导体(MOS)技术由于漏电流增加、静态功率耗散、开关频率受限等原因,已达到其最大盈利极限。量子点蜂窝自动机(QCA)技术是克服这些问题的较好解决方案之一,它没有物理传输电荷,完全依靠库仑力来实现细胞之间的相互作用,而且是一种无需晶体管的技术,不需要任何外部电压偏置。在当前的集成电路中,数据传输比以往任何时候都多,因此纠错和编码技术在可靠的数据通信中具有重要意义。认识到纠错在数据通信中的重要性与日俱增,特别是随着数据传输的广泛应用,本研究特别关注使用 QCA 实现增强型卷积编码器,用于数据传输中的纠错。我们还进行了与最新技术的比较研究,以检验拟议设计的性能。研究结果表明,与现有设计相比,我们提出的 1/2 速编码器的单元数减少了 33.34%,功率耗散减少了 77%;提出的 1/3 速编码器的单元数减少了 15.9%,功率耗散减少了 72%。
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引用次数: 0
Implementations of efficient non-blocking crossbar network with novel multiplexer design in quantum-dot cellular automata 利用量子点蜂窝自动机中的新型多路复用器设计实现高效无阻塞交叉网络
IF 2.9 4区 计算机科学 Q1 Mathematics Pub Date : 2024-04-21 DOI: 10.1016/j.nancom.2024.100509
Shangnan Dai, Guangjun Xie, Hui Zhang, Feifei Deng, Yongqiang Zhang

As an emerging nanotechnology, Quantum-dot Cellular Automata (QCA) has attracted extensive attentions due to its characteristics of high density, high speed, and low energy consumption. Modern high-performance System-on-Chips (SoCs) with multiple processors require interconnection networks to connect each core for improving data throughput and reducing latency, while the crossbar network is broadly used as a non-blocking interconnection architecture with high efficiency. In this paper, a method to design an efficient QCA-based N × N crossbar network utilizing optimally designed N:1 multiplexers (MUXs) is proposed, followed by a multi-layer and a single-layer implementation of its 8 × 8 design. A simplified matrix model is then introduced to provide a concise and intuitive switch control strategy, and expressions for cell count, area, latency, QCA cost, and QCA complexity of the proposed crossbar networks are derived according to the size N. Experimental results manifest that the proposed 8 × 8 crossbar networks have significant advantages on most performance parameters compared with other existing QCA-based networks.

作为一种新兴的纳米技术,量子点蜂窝自动机(QCA)因其高密度、高速度和低能耗的特点而受到广泛关注。拥有多个处理器的现代高性能片上系统(SoC)需要互联网络来连接各个内核,以提高数据吞吐量并减少延迟,而交叉条网络作为一种高效的无阻塞互联架构得到了广泛应用。本文提出了一种利用优化设计的 N:1 多路复用器 (MUX) 设计基于 QCA 的 N × N 交叉条网络的高效方法,并随后提出了其 8 × 8 设计的多层和单层实现方法。实验结果表明,与其他现有的基于 QCA 的网络相比,所提出的 8 × 8 交叉条网络在大多数性能参数上都具有显著优势。
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引用次数: 0
Impact of sole layer duple substrates on GA-based optimised graphene antennas for THz applications 基于 GA 的太赫兹应用优化石墨烯天线的单层双衬底影响
IF 2.9 4区 计算机科学 Q1 Mathematics Pub Date : 2024-04-15 DOI: 10.1016/j.nancom.2024.100508
Gurjeevan Singh , Karmjit Singh Sandha , Ankush Kansal

The widespread use of graphene patch antennas is escalating as evidence of their applicability in areas like 6 G communications and THz spectroscopy. Geometric uncertainty and fabrication issues while downsizing makes terahertz antenna design problematic. Graphene's electromagnetic and mechanical qualities make it ideal for miniaturizing antennas for Terahertz use. In the THz spectrum, a graphene antenna requires careful dielectric material selection since performance fall, especially efficiency. This paper compares dual band multi-layered genetic algorithm-based optimized antennas for the THz applications, especially spectroscopy and 6 G utilizing sole layer duple substrates concept, i.e., two distinct substrates at the same level between the ground and patch. Different antennas are designed using various substrates like Rogers RO3010, RO3210, RT5880, RT5880LZ, TMM 13i, Taconic TLY-3, RF-10, Silicon, & Teflon. Two segments of four antennas are planned; one has silicon as a common substrate with four additional materials, and another has Teflon. The proposed antenna's performance is assessed in terms of bandwidth, beamwidth, directivity, efficiency, gain, radiation pattern, return loss, and VSWR. The results reveal that Silicon and Rogers RT5880 LZ substrates-based antenna perform better in a segment I, with bandwidth (GHz) of 150.1 and 156.9, directivity (dBi) of 5.93 and 4.23, efficiency (%) of 76.65 and 78.98, and gain (dB) of 4.97 and 3.3. While in segment II, Teflon and Taconic RF-10-based antenna perform better with features 158 and 198 bandwidth, 6.43 and 4.43 directivity, 74 and 83 efficiency, and 4.67 and 3.65 gain.

石墨烯贴片天线在 6 G 通信和太赫兹光谱学等领域的应用日益广泛。几何不确定性和缩小尺寸时的制造问题使得太赫兹天线的设计成为难题。石墨烯的电磁和机械特性使其成为太赫兹天线小型化的理想选择。在太赫兹频谱中,石墨烯天线需要仔细选择介电材料,因为性能会下降,尤其是效率。本文比较了太赫兹应用中基于遗传算法的双波段多层优化天线,特别是利用单层双基板概念(即在地面和贴片之间的同一层面上有两个不同的基板)的光谱学和 6 G。设计不同的天线时使用了不同的基材,如罗杰斯 RO3010、RO3210、RT5880、RT5880LZ、TMM 13i、Taconic TLY-3、RF-10、硅和铁氟龙。计划制作两段共四根天线;其中一段以硅为共同基底,并使用四种附加材料,另一段使用聚四氟乙烯。从带宽、波束宽度、指向性、效率、增益、辐射模式、回波损耗和驻波比等方面对拟议天线的性能进行了评估。结果显示,基于硅和罗杰斯 RT5880 LZ 衬底的天线在 I 段性能较好,带宽(GHz)分别为 150.1 和 156.9,指向性(dBi)分别为 5.93 和 4.23,效率(%)分别为 76.65 和 78.98,增益(dB)分别为 4.97 和 3.3。而在第二部分中,基于 Teflon 和 Taconic RF-10 的天线性能更好,带宽分别为 158 和 198,指向性分别为 6.43 和 4.43,效率分别为 74 和 83,增益分别为 4.67 和 3.65。
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引用次数: 0
Advancing nanoscale computing: Efficient reversible ALU in quantum-dot cellular automata 推进纳米级计算:量子点蜂窝自动机中的高效可逆 ALU
IF 2.9 4区 计算机科学 Q1 Mathematics Pub Date : 2024-03-11 DOI: 10.1016/j.nancom.2024.100498
Shahrokh Nemattabar , Mohammad Mosleh , Majid Haghparast , Mohammad Kheyrandish

This paper presents a significant contribution to the field of nanoscale computing by proposing an innovative reversible Arithmetic and Logic Unit (ALU) implemented in Quantum-Dot Cellular Automata (QCA). Reversible logic and QCA technology offer promising alternatives to conventional CMOS technology, addressing the challenges of operating at nanoscale dimensions. The primary objective is to develop a highly efficient ALU capable of performing 26 distinct arithmetic and logical operations. The ALU design is based on a novel reversible full adder-subtractor optimized for minimal quantum cost, which is crucial for energy-efficient quantum computation. The evaluation encompasses various criteria related to reversibility, such as gate count, number of constant inputs, number of garbage outputs, and quantum cost. QCA-specific criteria, including cell count, occupied area, and clock cycles, are also considered. The outcomes of this research contribute to the advancement of cell-efficient nanoscale computing, with implications for quantum computation, emerging technologies, and future integrated circuit design.

本文提出了一种在量子点蜂窝自动机(QCA)中实现的创新型可逆算术逻辑单元(ALU),为纳米级计算领域做出了重大贡献。可逆逻辑和 QCA 技术为传统 CMOS 技术提供了前景广阔的替代方案,解决了在纳米级尺寸下运行所面临的挑战。其主要目标是开发一种能够执行 26 种不同算术和逻辑运算的高效 ALU。ALU 的设计基于一种新颖的可逆全加法器-减法器,经过优化,量子成本最小,这对高能效量子计算至关重要。评估包括与可逆性相关的各种标准,如门计数、常数输入数、垃圾输出数和量子成本。此外,还考虑了 QCA 的特定标准,包括单元数、占用面积和时钟周期。这项研究的成果有助于推动单元高效纳米级计算的发展,对量子计算、新兴技术和未来集成电路设计具有重要意义。
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引用次数: 0
Electric circuit representation of the human circulatory system to estimate the position of nanosensors in vessels 人体循环系统的电路表示法,用于估算纳米传感器在血管中的位置
IF 2.9 4区 计算机科学 Q1 Mathematics Pub Date : 2024-03-07 DOI: 10.1016/j.nancom.2024.100499
Jorge Torres Gómez , Jorge Luis González Rios , Falko Dressler

Nanodevices are the focus of research enhancing the detection and treatment of diseases in the human body. Focusing on the scenario where nanosensors are flowing with the blood in the human circulatory system (HCS), in this work, we investigate a model to predict their distribution along the various vessel segments. Although various approaches report solutions for localizing nanosensors in the body, it is also relevant to derive their stationary distribution along the vessel segments as a prior step to assess their actuation and sensing capabilities in the body. We use a Markov chain formulation to derive the stationary distribution of nanosensors. We evaluate the transition probabilities relying on the representation of vessels with electric circuit components. We implement the electric circuit representation of the left ventricle in the heart and the arteries to find the blood flow at vessel bifurcations and then compute the Markov chain probabilities. Our system also allows to reveal the dynamics of the movement of nanosensors with the human activity. We illustrate results in two regimes, as low and high activity, to mimic the case when being at rest or doing sports.

纳米设备是提高人体疾病检测和治疗水平的研究重点。在这项工作中,我们重点研究了纳米传感器在人体循环系统(HCS)中随血液流动的情况,并研究了一个模型来预测它们沿不同血管段的分布。虽然各种方法都报告了纳米传感器在体内定位的解决方案,但作为评估其在体内的致动和传感能力的先行步骤,推导其沿血管段的静态分布也很重要。我们使用马尔可夫链公式来推导纳米传感器的静态分布。我们利用电路元件来表示血管,从而评估过渡概率。我们实现了心脏左心室和动脉的电路表示,以找到血管分叉处的血流,然后计算马尔可夫链概率。我们的系统还能揭示纳米传感器随人体活动而移动的动态。我们展示了低活动和高活动两种状态下的结果,以模拟休息或运动时的情况。
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引用次数: 0
Experimental and theoretical exploration of terahertz channel performance through glass doors 透过玻璃门的太赫兹通道性能的实验和理论探索
IF 2.9 4区 计算机科学 Q1 Mathematics Pub Date : 2024-02-14 DOI: 10.1016/j.nancom.2024.100496
Da Li , Wenbo Liu , Menghan Wei , Jiacheng Liu , Guohao Liu , Peian Li , Houjun Sun , Jianjun Ma

In the evolving landscape of terahertz communication, the behavior of channels within indoor environments, particularly through glass doors, has garnered significant attention. This paper comprehensively investigates terahertz channel performance under such conditions, employing a measurement setup operational between 113 and 170 GHz. Analyzing scenarios frequently induced by human activity and environmental factors, like door movements, we established a comprehensive theoretical model. This model seamlessly integrates transmission, reflection, absorption, and diffraction mechanisms, leveraging the Fresnel formula, multi-layer transmission paradigm, and knife-edge diffraction theory. Our experimental results and theoretical predictions harmoniously align, revealing intricate dependencies, such as increased power loss at higher frequencies and larger incident angles. Furthermore, door interactions, whether opening or oscillations, significantly impact the terahertz channel. Notably, door edges lead to a power blockage surpassing the transmission loss of the glass itself but remaining inferior to metallic handle interferences. This paper's insights are pivotal for the design and fabrication of terahertz communication systems within indoor settings, pushing the boundaries of efficient and reliable communication.

在太赫兹通信不断发展的过程中,室内环境中的信道行为,尤其是透过玻璃门的信道行为,引起了人们的极大关注。本文采用 113 和 170 GHz 之间的测量装置,全面研究了这种条件下的太赫兹信道性能。通过分析人类活动和环境因素(如门的移动)经常诱发的情况,我们建立了一个全面的理论模型。该模型利用菲涅尔公式、多层传输范式和刀刃衍射理论,无缝整合了传输、反射、吸收和衍射机制。我们的实验结果与理论预测和谐一致,揭示了错综复杂的依赖关系,例如在频率较高和入射角度较大时,功率损耗会增加。此外,门的相互作用,无论是打开还是振荡,都会对太赫兹通道产生重大影响。值得注意的是,门边缘导致的功率阻塞超过了玻璃本身的传输损耗,但仍低于金属把手的干扰。本文的见解对室内太赫兹通信系统的设计和制造至关重要,推动了高效可靠通信的发展。
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引用次数: 0
The multiple fluorescent multi-bit DNA memory encoding system 多荧光多位 DNA 记忆编码系统
IF 2.9 4区 计算机科学 Q1 Mathematics Pub Date : 2024-02-09 DOI: 10.1016/j.nancom.2024.100497
Navchtsetseg Nergui , Jongdo Kim , Doyeon Lim , Wonjin Lee , Taeseok Kang , Sejung Kim , Min Suk Shim , Youngjun Song

The application of DNA monitoring has recently expanded into the information technology realm of DNA computing and storage systems, leveraging its capabilities for molecular computing and high-density data storage. Essential to this advancement are multi-color fluorescent signals attached to informational DNA, enabling simultaneous multidata reading in the DNA memory or storage system. Various fluorescent detection techniques, such as real-time polymerase chain reaction, next-generation sequencing, and fluorescence resonance energy transfer, have been investigated for DNA reactions and sequence data. Although proximity (less than 10 nm) between different fluorescent signals can lead to interference, controlling the distance of fluorescent molecules attached to DNA is a feasible solution. This study demonstrates a DNA molecular memory system using multiple fluorescent molecules. We examined the independent hybridization of three different fluorescent DNA molecules to DNA templates with three sites for fluorescent attachment on 17 nt DNAs. The study focused on two multi-bit DNA molecules hybridized to the template DNA, assessing their fluorescence emission intensities at various excitation wavelengths. Two multi-bit DNA molecules, which were hybridized onto the template DNA, were investigated for fluorescence emission intensities by various excitation wavelengths. Although the emission intensities of the two multi-bit DNA molecules were not significantly increased by another fluorescent molecule, each excitation wavelength has provided more effective emission intensity levels for DNA signal detection. Furthermore, we developed a three-bit DNA molecular memory system using triple-level DNA molecules. These multi-color DNA systems could be extended to arithmetic and logical computing.

DNA 监测的应用最近已扩展到 DNA 计算和存储系统的信息技术领域,充分利用了其分子计算和高密度数据存储的能力。这一进步的关键在于信息 DNA 上附着的多色荧光信号,可在 DNA 存储器或存储系统中同时读取多种数据。目前已针对 DNA 反应和序列数据研究了各种荧光检测技术,如实时聚合酶链反应、新一代测序和荧光共振能量转移。虽然不同荧光信号之间的距离过近(小于 10 纳米)会导致干扰,但控制附着在 DNA 上的荧光分子的距离是一种可行的解决方案。本研究展示了一种使用多种荧光分子的 DNA 分子记忆系统。我们研究了三种不同的荧光 DNA 分子与 DNA 模板的独立杂交,在 17 nt DNA 上有三个荧光附着点。研究的重点是与模板 DNA 杂交的两个多位 DNA 分子,评估它们在不同激发波长下的荧光发射强度。研究人员对杂交到模板 DNA 上的两个多位 DNA 分子在不同激发波长下的荧光发射强度进行了研究。虽然两个多位 DNA 分子的发射强度在另一个荧光分子的作用下没有明显提高,但每种激发波长都为 DNA 信号检测提供了更有效的发射强度水平。此外,我们还利用三级 DNA 分子开发了一种三位 DNA 分子记忆系统。这些多色 DNA 系统可扩展到算术和逻辑运算领域。
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引用次数: 0
Quantum-dot Cellular Automata Placement and Routing with Hierarchical Algorithm 采用分层算法的量子点蜂窝自动机安置和路由选择
IF 2.9 4区 计算机科学 Q1 Mathematics Pub Date : 2024-02-02 DOI: 10.1016/j.nancom.2024.100495
Bing Zhang , Fei Peng , Gaisheng Li , Yangshuai Li , Guangjun Xie

To meet the needs of the market launch, placement and routing(P&R) algorithms for conventional circuits have started to adopt a hierarchical design, divide and conquer philosophy for the layout of VLSI circuits. Quantum-dot cellular automata (QCA) circuits are considered a solution to overcome the limitations of Moore’s Law. However, the current automated design of QCA circuits is still in its preliminary stages. This paper uses a hierarchical structure, which borrows from traditional circuits that should be laid out in large-scale circuits, to hierarchically process QCA circuits, laying them out layer by layer while using the A* algorithm for wiring to find feasible solutions. The algorithm is implemented using the C++ programming language, and simulation results verify the correctness of the algorithm.

为了满足市场启动的需要,传统电路的布局和布线(P&R)算法开始采用分层设计、分而治之的理念来布局超大规模集成电路。量子点蜂窝自动机(QCA)电路被认为是克服摩尔定律限制的一种解决方案。然而,目前 QCA 电路的自动化设计仍处于初级阶段。本文借鉴大规模电路中应布局的传统电路,采用分层结构对 QCA 电路进行分层处理,逐层布局,同时使用 A* 算法布线,以找到可行的解决方案。该算法使用 C++ 编程语言实现,仿真结果验证了算法的正确性。
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引用次数: 0
Emission rate optimization in diffusion-based molecular communication among mobile bacteria 移动细菌间基于扩散的分子通讯中的发射率优化
IF 2.9 4区 计算机科学 Q1 Mathematics Pub Date : 2023-12-14 DOI: 10.1016/j.nancom.2023.100490
Xuancheng Jin, Zhen Cheng, Jie Sun

In quorum sensing (QS), bacteria exchange information by using molecular signals to work together. In this paper, we study diffusion-based molecular communication with the QS mechanism between the transmitter node and receiver node which are composed of a population of mobile bacteria in a cluster, respectively. The expression of average bit error probability (BEP) at a receiver bacterium is derived. Furthermore, we use the projected gradient descent (PGD) algorithm to solve the optimization problem whose objective is to minimize the average BEP under emission rate constraints which require that the emission rate of each transmitter bacterium has lower and upper bounds. Finally, the numerical results show the PGD algorithm has good convergence behaviors and it is more efficient in finding the optimal emission rate with fewer iterations than genetic algorithm. The obtained results are expected to provide guidance in designing QS-based molecular communication system with lower average BEP.

在法定人数感应(QS)中,细菌通过分子信号交换信息,共同工作。本文研究了基于扩散的 QS 机制的分子通信,研究对象分别是由集群中的移动细菌群组成的发送节点和接收节点。得出了接收细菌的平均比特错误概率(BEP)表达式。此外,我们还使用了投影梯度下降(PGD)算法来解决优化问题,其目标是在发射率约束条件下最小化平均误码率,发射率约束条件要求每个发射细菌的发射率都有下限和上限。最后,数值结果表明 PGD 算法具有良好的收敛性,与遗传算法相比,它能以更少的迭代次数更有效地找到最佳发射率。这些结果有望为设计平均 BEP 更低的基于 QS 的分子通讯系统提供指导。
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引用次数: 0
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Nano Communication Networks
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