Pub Date : 2024-09-07DOI: 10.1016/j.jnha.2024.100353
Bingyan Yu , Shize Jia , Tiantian Sun , Jieliang Liu , Junguo Jin , Shanghong Zhang , Qiyao Xiao , Haojian Dong , Yanqiu Ou
Objectives
Sarcopenic obesity (SO) has been found to increase the risk of metabolic disorders, however, its relationship with cardiometabolic multimorbidity (CMM) remains unexplored. This study aims to investigate the potential association between SO and CMM in the middle-aged and older population.
Methods
Our study subjects were from CHARLS. SO was defined as the combination of impaired grip strength (grip strength <28 kg for men and <18 kg for women) and increased body mass index (BMI ≥25 kg/m2). CMM was defined as having two or more cardiometabolic diseases, including diabetes mellitus, stroke, and heart disease. The participants were divided into four groups according to their sarcopenia and obesity status, and logistic regression analysis was used to examine the association between SO and CMM.
Results
A total of 15,252 study subjects were included in the cross-sectional study, with an average age of 60.6 years and a male proportion of 47.4%. In the cross-sectional analysis conducted in 2015, the prevalence of CMM was highest in the SO group (9.1%), followed by the obesity (3.7%) and sarcopenia (3.5%) group. After adjustment for confounding factors, SO [OR (95%CI): 2.453 (1.742−3.455)], sarcopenia [OR (95% CI): 1.601 (1.157−2.217)], obesity [OR (95% CI): 1.446 (1.107−1.888)] were all observed to be associated with CMM, with the strongest association in the SO group. Furthermore, in the longitudinal analysis, only the SO group demonstrated a significant risk for developing CMM [OR (95% CI): 2.302 (1.239−4.228)].
Conclusions
SO was independently and positively associated with CMM in middle-aged and older population.
{"title":"Sarcopenic obesity is associated with cardiometabolic multimorbidity in Chinese middle-aged and older adults: a cross-sectional and longitudinal study","authors":"Bingyan Yu , Shize Jia , Tiantian Sun , Jieliang Liu , Junguo Jin , Shanghong Zhang , Qiyao Xiao , Haojian Dong , Yanqiu Ou","doi":"10.1016/j.jnha.2024.100353","DOIUrl":"10.1016/j.jnha.2024.100353","url":null,"abstract":"<div><h3>Objectives</h3><p>Sarcopenic obesity (SO) has been found to increase the risk of metabolic disorders, however, its relationship with cardiometabolic multimorbidity (CMM) remains unexplored. This study aims to investigate the potential association between SO and CMM in the middle-aged and older population.</p></div><div><h3>Methods</h3><p>Our study subjects were from CHARLS. SO was defined as the combination of impaired grip strength (grip strength <28 kg for men and <18 kg for women) and increased body mass index (BMI ≥25 kg/m<sup>2</sup>). CMM was defined as having two or more cardiometabolic diseases, including diabetes mellitus, stroke, and heart disease. The participants were divided into four groups according to their sarcopenia and obesity status, and logistic regression analysis was used to examine the association between SO and CMM.</p></div><div><h3>Results</h3><p>A total of 15,252 study subjects were included in the cross-sectional study, with an average age of 60.6 years and a male proportion of 47.4%. In the cross-sectional analysis conducted in 2015, the prevalence of CMM was highest in the SO group (9.1%), followed by the obesity (3.7%) and sarcopenia (3.5%) group. After adjustment for confounding factors, SO [OR (95%CI): 2.453 (1.742−3.455)], sarcopenia [OR (95% CI): 1.601 (1.157−2.217)], obesity [OR (95% CI): 1.446 (1.107−1.888)] were all observed to be associated with CMM, with the strongest association in the SO group. Furthermore, in the longitudinal analysis, only the SO group demonstrated a significant risk for developing CMM [OR (95% CI): 2.302 (1.239−4.228)].</p></div><div><h3>Conclusions</h3><p>SO was independently and positively associated with CMM in middle-aged and older population.</p></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100353"},"PeriodicalIF":4.3,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004408/pdfft?md5=4fe4b14d0059691cb74ae24f45723a9f&pid=1-s2.0-S1279770724004408-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142149659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-07DOI: 10.1016/j.jnha.2024.100356
Shanshan Jia , Lu Liu , Xingwei Huo, Lirong Sun, Xiaoping Chen
{"title":"Association of novel anthropometric indices with all-cause mortality in hypertensive patients: Evidence from NHANES 2007–2018","authors":"Shanshan Jia , Lu Liu , Xingwei Huo, Lirong Sun, Xiaoping Chen","doi":"10.1016/j.jnha.2024.100356","DOIUrl":"10.1016/j.jnha.2024.100356","url":null,"abstract":"","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100356"},"PeriodicalIF":4.3,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004433/pdfft?md5=fb683ad8bf095646a509205035ce1d9f&pid=1-s2.0-S1279770724004433-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142149660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-05DOI: 10.1016/j.jnha.2024.100350
Xiao-Ming Zhang , Lihuan Chen , Xin You , Aizhang Zhu , Jiang Wang , Rui Zeng , Fayi Xie , Dongmei Ye , Wan Zhu , Ke Zhu , Tenghui Fan , Yunzhi Yang , Wen-wu Zhang , Conghua Wang
{"title":"The association between weight-adjusted waist index and frailty defined by Fried's Frailty Phenotype among Chinese people","authors":"Xiao-Ming Zhang , Lihuan Chen , Xin You , Aizhang Zhu , Jiang Wang , Rui Zeng , Fayi Xie , Dongmei Ye , Wan Zhu , Ke Zhu , Tenghui Fan , Yunzhi Yang , Wen-wu Zhang , Conghua Wang","doi":"10.1016/j.jnha.2024.100350","DOIUrl":"10.1016/j.jnha.2024.100350","url":null,"abstract":"","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100350"},"PeriodicalIF":4.3,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004378/pdfft?md5=1f6e845a3a80268a3c8e976bcd79e628&pid=1-s2.0-S1279770724004378-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-05DOI: 10.1016/j.jnha.2024.100355
Yan Zhuang , Laifu Li , Yanqi Zhang , Fei Dai , Jingyan Sun
{"title":"The relationship between mineral mixture intake and cognitive function in older US adults: a cross-sectional NHANES study","authors":"Yan Zhuang , Laifu Li , Yanqi Zhang , Fei Dai , Jingyan Sun","doi":"10.1016/j.jnha.2024.100355","DOIUrl":"10.1016/j.jnha.2024.100355","url":null,"abstract":"","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100355"},"PeriodicalIF":4.3,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004421/pdfft?md5=1f052d605871907b2dec8fb9faad40c7&pid=1-s2.0-S1279770724004421-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-05DOI: 10.1016/j.jnha.2024.100354
Liang-Kung Chen
{"title":"Integrating precision health with multidomain interventions to advance strategies for healthy aging","authors":"Liang-Kung Chen","doi":"10.1016/j.jnha.2024.100354","DOIUrl":"10.1016/j.jnha.2024.100354","url":null,"abstract":"","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100354"},"PeriodicalIF":4.3,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S127977072400441X/pdfft?md5=db552796ba4b15bf26700eba055d60d5&pid=1-s2.0-S127977072400441X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-03DOI: 10.1016/j.jnha.2024.100349
Paulina Ioannidou , Zsuzsanna Dóró , Jan Schalla , Wim Wätjen , Patrick Diel , Eduard Isenmann
Background
Menopause has a significant impact on the endocrine system of middle-aged women, resulting in a loss of skeletal muscle mass (SMM), changes in fat mass (FM) and a reduction in strength capacity. Resistance training (RT) and a high-protein diet (HPD) are effective methods for maintaining or increasing SMM. This study aims to determine the effects of HPD and RT on body composition, muscle thickness and strength capacity in postmenopausal women.
Methods
In total 55 healthy postmenopausal women (age: 58.2 ± 5.6 years, weight 69.1 ± 9.6 kg, height 166.5 ± 6.5 cm) successfully participated in the study. The women were randomly assigned to either group: training + protein (2.5 g/kg fat-free mass (FFM)) (n = 15; TP); only training (n = 12; T); only protein (2.5 g/kg FFM) (n = 14; CP) or control (n = 14; C). TP and T performed RT for 12 weeks with three training sessions and five exercises each. CP and C were prohibited from training during the period. The main parameters analysed for body composition were FFM, SMM, FM, muscle thickness of the M. rectus femoris, M. biceps femoris, M. triceps brachii and M. biceps brachii muscles. Strength was tested using a dynamometer for grip strength and 1-RM in the squat (BBS) and deadlift (DL).
Results
The SMM significantly increased by RT (TP: (Δ+1.4 ± 0.9 kg; p < 0.05; d = 0.4; T: Δ+1.2 ± 1.3kg; p < 0.05; d = 0.3) and FM could be reduced only in T: (Δ−2.4 ± 2.9 kg; p < 0.05; d = 0.3). In muscle thickness a significant increase in the M. biceps brachii in both training groups (TP: (Δ+0.4 ± 0.3 cm; p < 0.05; d = 1.6; T: (Δ+0.3 ± 0.3 cm; p < 0.05; d = 0.9) and in M. biceps femoris only in TP (Δ+0.3 ± 0.4 cm; p < 0.05; d = 0.9) were observed. HPD without training does not affect body composition, A significant increase in grip strength (TP: Δ+4.7 ± 2.4 kg; (p < 0.05; d = 1.5; T: (Δ+3.6 ± 3.0 kg; p < 0.05; d = 0.8), in BBS (TP: (Δ+30.0 ± 14.2 kg; p < 0.05; d = 1.5; T: (Δ+34.0 ± 12.0 kg; p < 0.05; d = 2.4) and in DL (TP: (Δ+20.8 ± 10.3 kg; p < 0.05; d = 1.6; T: (Δ+22.1 ± 7.6 kg; p < 0.05; d = 2.0) was observed in both training groups. The CP also recorded a significant increase in the BBS (Δ+7.5 ± 5.4 kg; p < 0.05; d = 0.4) and in DL (Δ+5.5 ± 7.7 kg; p < 0.05; d = 0.5). No significant differences were detected for TP and T for any of the parameters.
Conclusion
The results indicate that RT enhances body composition and strength capacity in postmenopausal women and is a preventive strategy against muscle atrophy. Besides HPD without training has a trivial significant effect on BBS and DL. HPD with RT has no clear additive effect on body composition and strength capacity. Further studies are needed to confirm these observations.
背景绝经对中年女性的内分泌系统有重大影响,导致骨骼肌质量(SMM)减少、脂肪量(FM)变化和力量能力下降。阻力训练(RT)和高蛋白饮食(HPD)是维持或增加骨骼肌质量的有效方法。本研究旨在确定 HPD 和 RT 对绝经后妇女的身体成分、肌肉厚度和力量能力的影响。方法共有 55 名健康的绝经后妇女(年龄:58.2 ± 5.6 岁,体重 69.1 ± 9.6 公斤,身高 166.5 ± 6.5 厘米)成功参与了本研究。这些妇女被随机分配到以下任一组:训练+蛋白质(2.5 克/千克无脂质量(FFM))(n = 15;TP);仅训练(n = 12;T);仅蛋白质(2.5 克/千克无脂质量(FFM))(n = 14;CP)或对照组(n = 14;C)。TP和T进行了为期12周的RT训练,各进行了三次训练和五次练习。CP 和 C 在此期间禁止训练。身体成分分析的主要参数包括 FFM、SMM、FM,以及股直肌、股二头肌、肱三头肌和肱二头肌的肌肉厚度。使用测力计测试握力以及深蹲(BBS)和负重举(DL)的 1-RM 力量。4 ± 0.9 kg; p < 0.05; d = 0.4; T: Δ+1.2 ± 1.3 kg; p < 0.05; d = 0.3),而 FM 仅在 T: (Δ-2.4 ± 2.9 kg; p < 0.05; d = 0.3) 时才会减少。在肌肉厚度方面,两个训练组的肱二头肌(TP:(Δ+0.4 ± 0.3 cm; p < 0.05; d = 1.6;T:(Δ+0.3 ± 0.3 cm; p < 0.05; d = 0.9)和股二头肌(TP:(Δ+0.3 ± 0.4 cm; p < 0.05; d = 0.9)都有明显增加。不进行训练的 HPD 不会影响身体成分,但握力(TP:Δ+4.7 ± 2.4 kg;p <;0.05;d = 1.5;T:Δ+3.6 ± 3.0 kg;p <;0.05;d = 0.8)、BBS(TP:Δ+30.0 ± 14.2 kg; p < 0.05; d = 1.5; T: (Δ+34.0 ± 12.0 kg; p < 0.05; d = 2.4)和 DL (TP: (Δ+20.8 ± 10.3 kg; p < 0.05; d = 1.6; T: (Δ+22.1 ± 7.6 kg; p < 0.05; d = 2.0)中都观察到。CP组的BBS(Δ+7.5 ± 5.4 kg;p <;0.05;d = 0.4)和DL(Δ+5.5 ± 7.7 kg;p <;0.05;d = 0.5)也有明显增加。结果表明,RT 可增强绝经后妇女的身体成分和力量能力,是预防肌肉萎缩的一种策略。此外,不进行训练的 HPD 对 BBS 和 DL 的影响微不足道。HPD 和 RT 对身体成分和力量能力没有明显的叠加效应。要证实这些观察结果,还需要进一步的研究。
{"title":"Analysis of combinatory effects of free weight resistance training and a high-protein diet on body composition and strength capacity in postmenopausal women - A 12-week randomized controlled trial","authors":"Paulina Ioannidou , Zsuzsanna Dóró , Jan Schalla , Wim Wätjen , Patrick Diel , Eduard Isenmann","doi":"10.1016/j.jnha.2024.100349","DOIUrl":"10.1016/j.jnha.2024.100349","url":null,"abstract":"<div><h3>Background</h3><p>Menopause has a significant impact on the endocrine system of middle-aged women, resulting in a loss of skeletal muscle mass (SMM), changes in fat mass (FM) and a reduction in strength capacity. Resistance training (RT) and a high-protein diet (HPD) are effective methods for maintaining or increasing SMM. This study aims to determine the effects of HPD and RT on body composition, muscle thickness and strength capacity in postmenopausal women.</p></div><div><h3>Methods</h3><p>In total 55 healthy postmenopausal women (age: 58.2 ± 5.6 years, weight 69.1 ± 9.6 kg, height 166.5 ± 6.5 cm) successfully participated in the study. The women were randomly assigned to either group: training + protein (2.5 g/kg fat-free mass (FFM)) (n = 15; TP); only training (n = 12; T); only protein (2.5 g/kg FFM) (n = 14; CP) or control (n = 14; C). TP and T performed RT for 12 weeks with three training sessions and five exercises each. CP and C were prohibited from training during the period. The main parameters analysed for body composition were FFM, SMM, FM, muscle thickness of the M. rectus femoris, M. biceps femoris, M. triceps brachii and M. biceps brachii muscles. Strength was tested using a dynamometer for grip strength and 1-RM in the squat (BBS) and deadlift (DL).</p></div><div><h3>Results</h3><p>The SMM significantly increased by RT (TP: (Δ+1.4 ± 0.9 kg; p < 0.05; d = 0.4; T: Δ+1.2 ± 1.3kg; p < 0.05; d = 0.3) and FM could be reduced only in T: (Δ−2.4 ± 2.9 kg; p < 0.05; d = 0.3). In muscle thickness a significant increase in the M. biceps brachii in both training groups (TP: (Δ+0.4 ± 0.3 cm; p < 0.05; d = 1.6; T: (Δ+0.3 ± 0.3 cm; p < 0.05; <em>d =</em> 0.9) and in M. biceps femoris only in TP (Δ+0.3 ± 0.4 cm; p < 0.05; <em>d =</em> 0.9) were observed. HPD without training does not affect body composition, A significant increase in grip strength (TP: Δ+4.7 ± 2.4 kg; (p < 0.05; <em>d</em> = 1.5; T: (Δ+3.6 ± 3.0 kg; p < 0.05; <em>d</em> = 0.8), in BBS (TP: (Δ+30.0 ± 14.2 kg; p < 0.05; <em>d</em> = 1.5; T: (Δ+34.0 ± 12.0 kg; p < 0.05; <em>d</em> = 2.4) and in DL (TP: (Δ+20.8 ± 10.3 kg; p < 0.05; <em>d</em> = 1.6; T: (Δ+22.1 ± 7.6 kg; p < 0.05; <em>d</em> = 2.0) was observed in both training groups. The CP also recorded a significant increase in the BBS (Δ+7.5 ± 5.4 kg; p < 0.05; <em>d</em> = 0.4) and in DL (Δ+5.5 ± 7.7 kg; p < 0.05; <em>d</em> = 0.5). No significant differences were detected for TP and T for any of the parameters.</p></div><div><h3>Conclusion</h3><p>The results indicate that RT enhances body composition and strength capacity in postmenopausal women and is a preventive strategy against muscle atrophy. Besides HPD without training has a trivial significant effect on BBS and DL. HPD with RT has no clear additive effect on body composition and strength capacity. Further studies are needed to confirm these observations.</p></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100349"},"PeriodicalIF":4.3,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004366/pdfft?md5=4d308f52dd27111ab6fc62f8b831bf5a&pid=1-s2.0-S1279770724004366-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142129969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-30DOI: 10.1016/j.jnha.2024.100347
Shanshan Li , Xiaoyan Wang , Xinmei Li , Weiwei Zhang , Yingying Guo , Nuo Xu , Junkai Luo , Shankuan Zhu , Wei He
Background
Cardiovascular disease originates in early life. We aimed to investigate the association between breastfeeding in infancy and cardiovascular disease in adult life.
Methods
We followed 364,240 participants from UK Biobank aged 40–73 years from 2006 – 2010 to 2021. Information on breastfeeding in infancy was self-reported by questionnaire. Cox proportional hazard regression models were used to estimate the hazard ratios (HR) and 95% confidence intervals (CI) for the association between breastfeeding and cardiovascular disease in middle-aged and older adulthood. The multivariable Cox models were used by adjusting for the age (used as the time scale), sex, ethnicity, assessment centre, birth weight, multiple birth status, maternal smoking during pregnancy, Townsend deprivation index, smoking status, alcohol drinker status, physical activity, and menopausal status for women. Binary and multinomial multivariable logistic regression models were used to explore the associations of breastfeeding in infancy with cardiovascular disease risk factors including obesity, body composition, metabolic and inflammatory disorders.
Results
During a median of 12.6 years of follow-up, we documented 29,796 new cases of cardiovascular disease, including 24,797 coronary heart disease and 6229 stroke. The multivariable adjusted HRs for breastfed versus non-breastfed were 0.94 (95% CI: 0.91, 0.96) for cardiovascular disease, 0.94 (95% CI: 0.91, 0.96) for coronary heart disease, and 0.95 (95% CI: 0.89, 1.01) for stroke. Furthermore, the strength of observed association between breastfeeding and cardiovascular disease seems to decrease with age (P for interaction <0.001), and increase with polygenic risk for cardiovascular disease (P for interaction <0.001). Consistently, breastfeeding in infancy was associated with cardiovascular disease risk factors including lower body mass index 0.92 (95% CI: 0.89, 0.95), body fat percentage 0.85 (95% CI: 0.83, 0.87), android to gynoid fat ratio 0.89 (95% CI: 0.83, 0.96), visceral adipose tissue 0.92 (95% CI: 0.84, 1.01), as well as lower C-reactive protein level 0.95 (95% CI: 0.94, 0.97) and a lower risk of metabolic syndrome 0.89 (95% CI: 0.85, 0.92).
Conclusions
Breastfeeding in infancy was associated with a lower risk of cardiovascular disease in middle-aged and older adulthood. Promoting breastfeeding is vital not only for promoting child health, but also for halting the increasing trend of cardiovascular disease in adults.
{"title":"Breastfeeding in infancy and cardiovascular disease in middle-aged and older adulthood: a prospective study of 0.36 million UK Biobank participants","authors":"Shanshan Li , Xiaoyan Wang , Xinmei Li , Weiwei Zhang , Yingying Guo , Nuo Xu , Junkai Luo , Shankuan Zhu , Wei He","doi":"10.1016/j.jnha.2024.100347","DOIUrl":"10.1016/j.jnha.2024.100347","url":null,"abstract":"<div><h3>Background</h3><p>Cardiovascular disease originates in early life. We aimed to investigate the association between breastfeeding in infancy and cardiovascular disease in adult life.</p></div><div><h3>Methods</h3><p>We followed 364,240 participants from UK Biobank aged 40–73 years from 2006 – 2010 to 2021. Information on breastfeeding in infancy was self-reported by questionnaire. Cox proportional hazard regression models were used to estimate the hazard ratios (HR) and 95% confidence intervals (CI) for the association between breastfeeding and cardiovascular disease in middle-aged and older adulthood. The multivariable Cox models were used by adjusting for the age (used as the time scale), sex, ethnicity, assessment centre, birth weight, multiple birth status, maternal smoking during pregnancy, Townsend deprivation index, smoking status, alcohol drinker status, physical activity, and menopausal status for women. Binary and multinomial multivariable logistic regression models were used to explore the associations of breastfeeding in infancy with cardiovascular disease risk factors including obesity, body composition, metabolic and inflammatory disorders.</p></div><div><h3>Results</h3><p>During a median of 12.6 years of follow-up, we documented 29,796 new cases of cardiovascular disease, including 24,797 coronary heart disease and 6229 stroke. The multivariable adjusted HRs for breastfed versus non-breastfed were 0.94 (95% CI: 0.91, 0.96) for cardiovascular disease, 0.94 (95% CI: 0.91, 0.96) for coronary heart disease, and 0.95 (95% CI: 0.89, 1.01) for stroke. Furthermore, the strength of observed association between breastfeeding and cardiovascular disease seems to decrease with age (P for interaction <0.001), and increase with polygenic risk for cardiovascular disease (P for interaction <0.001). Consistently, breastfeeding in infancy was associated with cardiovascular disease risk factors including lower body mass index 0.92 (95% CI: 0.89, 0.95), body fat percentage 0.85 (95% CI: 0.83, 0.87), android to gynoid fat ratio 0.89 (95% CI: 0.83, 0.96), visceral adipose tissue 0.92 (95% CI: 0.84, 1.01), as well as lower C-reactive protein level 0.95 (95% CI: 0.94, 0.97) and a lower risk of metabolic syndrome 0.89 (95% CI: 0.85, 0.92).</p></div><div><h3>Conclusions</h3><p>Breastfeeding in infancy was associated with a lower risk of cardiovascular disease in middle-aged and older adulthood. Promoting breastfeeding is vital not only for promoting child health, but also for halting the increasing trend of cardiovascular disease in adults.</p></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100347"},"PeriodicalIF":4.3,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004342/pdfft?md5=280023a556ea726dd67cec407db82173&pid=1-s2.0-S1279770724004342-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142098606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-29DOI: 10.1016/j.jnha.2024.100348
Dieying Jiang , Jianyang Luo
{"title":"Letter to the Editor regarding “The Role of Sarcopenia in Overactive Bladder in Adults in the United States: Retrospective Analysis of NHANES 2011–2018”","authors":"Dieying Jiang , Jianyang Luo","doi":"10.1016/j.jnha.2024.100348","DOIUrl":"10.1016/j.jnha.2024.100348","url":null,"abstract":"","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100348"},"PeriodicalIF":4.3,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004354/pdfft?md5=b3fe4f971552baa9b33ee8561076e82d&pid=1-s2.0-S1279770724004354-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142098607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-26DOI: 10.1016/j.jnha.2024.100344
S. Bauer , L. Reiter , P.J.M. Weijs , J.D. Schoufour , Y. Boirie , E. Topinková , R.G. Memelink , A.M. Verreijen , A. Borenich , D. Eglseer , the SO-NUTS consortium
Objectives
Adherence to lifestyle interventions is crucial for the treatment of obesity. However, there is little research about adherence to lifestyle interventions in persons around retirement age. The objectives of this study are (1) to identify factors associated with the adherence to resistance training and a hypocaloric diet and (2) to describe the association between adherence and changes in body composition outcome parameters.
Design
This secondary data analysis included three randomized controlled trials.
Setting & participants
The inclusion criteria of the participants were an age of 55–75 years, a BMI ≥ 25 kg/m2 and receiving both a hypocaloric diet and resistance training. All participants were residing in the community.
Measurements
Adherence to hypocaloric diet was measured through the mean dietary intake on the basis of a 3-day dietary record. If the participant consumed at least 600 kcal less than the individual caloric requirements, they were considered adherent. Adherence to resistance training was achieved if ≥67% of the recommended training sessions were attended over the course of the study periods.
Results
232 participants were included, 47.0% female, mean age 64.0 (±5.5) years. 80.2% adhered to resistance training and 51.3% adhered to a hypocaloric diet. Older age (Beta 0.41; 95% CI 0.05, 0.78; p = 0.028) and male sex (Beta 7.7; 95% CI 3.6, 11; p < 0.001) were associated with higher resistance training adherence. A higher BMI at baseline (Beta 6.4; 95% CI 3.6, 9.2; p < 0.001) and male sex (Beta 65; 95% CI 41, 88; p < 0.001) were associated with higher adherence to hypocaloric diet.
Conclusion
We identified several associated factors (sex, age and BMI at baseline) that should be considered to promote adherence in future lifestyle intervention studies in persons around retirement age. We recommend including behavior change techniques in lifestyle interventions and consider sex-specific interventions to improve the adherence of women.
目标坚持生活方式干预对治疗肥胖症至关重要。然而,有关退休人员坚持生活方式干预的研究却很少。本研究的目的是:(1)确定与坚持阻力训练和低热量饮食相关的因素;(2)描述坚持阻力训练与身体成分结果参数变化之间的关系。测量低热量饮食的依从性根据 3 天饮食记录的平均饮食摄入量进行测量。如果参与者摄入的热量比个人热量需求至少少 600 千卡,则被视为坚持低热量饮食。如果在研究期间参加了≥67%的推荐训练课程,则视为坚持了阻力训练。结果232名参与者中,47.0%为女性,平均年龄为64.0(±5.5)岁。80.2%的参与者坚持阻力训练,51.3%的参与者坚持低热量饮食。年龄越大(Beta 0.41; 95% CI 0.05, 0.78; p = 0.028)、性别为男性(Beta 7.7; 95% CI 3.6, 11; p <0.001),坚持阻力训练的比例越高。基线体重指数(BMI)较高(Beta 6.4;95% CI 3.6,9.2;p <;0.001)和男性(Beta 65;95% CI 41,88;p <;0.001)与低热量饮食坚持率较高相关。我们建议在生活方式干预中加入行为改变技术,并考虑针对不同性别的干预措施,以提高女性的坚持率。
{"title":"Adherence to resistance training and hypocaloric diet among persons near retirement age — A secondary data analysis of three randomized controlled trials","authors":"S. Bauer , L. Reiter , P.J.M. Weijs , J.D. Schoufour , Y. Boirie , E. Topinková , R.G. Memelink , A.M. Verreijen , A. Borenich , D. Eglseer , the SO-NUTS consortium","doi":"10.1016/j.jnha.2024.100344","DOIUrl":"10.1016/j.jnha.2024.100344","url":null,"abstract":"<div><h3>Objectives</h3><p>Adherence to lifestyle interventions is crucial for the treatment of obesity. However, there is little research about adherence to lifestyle interventions in persons around retirement age. The objectives of this study are (1) to identify factors associated with the adherence to resistance training and a hypocaloric diet and (2) to describe the association between adherence and changes in body composition outcome parameters.</p></div><div><h3>Design</h3><p>This secondary data analysis included three randomized controlled trials.</p></div><div><h3>Setting & participants</h3><p>The inclusion criteria of the participants were an age of 55–75 years, a BMI ≥ 25 kg/m<sup>2</sup> and receiving both a hypocaloric diet and resistance training. All participants were residing in the community.</p></div><div><h3>Measurements</h3><p>Adherence to hypocaloric diet was measured through the mean dietary intake on the basis of a 3-day dietary record. If the participant consumed at least 600 kcal less than the individual caloric requirements, they were considered adherent. Adherence to resistance training was achieved if ≥67% of the recommended training sessions were attended over the course of the study periods.</p></div><div><h3>Results</h3><p>232 participants were included, 47.0% female, mean age 64.0 (±5.5) years. 80.2% adhered to resistance training and 51.3% adhered to a hypocaloric diet. Older age (Beta 0.41; 95% CI 0.05, 0.78; <em>p</em> = 0.028) and male sex (Beta 7.7; 95% CI 3.6, 11; <em>p</em> < 0.001) were associated with higher resistance training adherence. A higher BMI at baseline (Beta 6.4; 95% CI 3.6, 9.2; <em>p</em> < 0.001) and male sex (Beta 65; 95% CI 41, 88; <em>p</em> < 0.001) were associated with higher adherence to hypocaloric diet.</p></div><div><h3>Conclusion</h3><p>We identified several associated factors (sex, age and BMI at baseline) that should be considered to promote adherence in future lifestyle intervention studies in persons around retirement age. We recommend including behavior change techniques in lifestyle interventions and consider sex-specific interventions to improve the adherence of women.</p></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100344"},"PeriodicalIF":4.3,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004317/pdfft?md5=77660cb8999b9fe3cb8ee5c7bff2e5ea&pid=1-s2.0-S1279770724004317-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142075918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-26DOI: 10.1016/j.jnha.2024.100346
Lucía Carcedo-Argüelles , Sara Llamas-Fernández , María del Mar Fernández-Álvarez , Francisco Félix Caballero-Díaz , Fernando Rodríguez-Artalejo , Esther López-García , Alberto Lana
Objective
The aim was to examine the association between social frailty and diet quality in adults over 65 years of age, and whether results differed by sex.
Design
Population-based cross-sectional study using data from the Spanish National Health Survey.
Participants
5,071 community-dwelling people ≥65 years from Spain.
Measurements
Social frailty was deemed to exist when the person both lived alone and had low social support, measured with the Duke-UNC scale. Diet was assessed with the Spanish Healthy Eating Index (S-HEI), ranging from 0 to 100 points (highest diet quality). Means and 95% confidence intervals of the S-HEI score for each social frailty group were calculated using linear regressions, with socially robust people as reference. Analyses were adjusted for main confounders, including sociodemographic, lifestyle and morbidity variables.
Results
There were no differences in the S-HEI adjusted mean of socially frail (74.3 points, 95%CI: 73.4−75.2) compared to socially robust older adults (75.4 points; 95%CI: 75.1−75.7). In sex-stratified analyses, the S-HEI adjusted mean of socially frail men (71.9 points; 95%CI: 70.6−73.2) was lower than robust men (74.8 points; 95%CI: 74.4−75.3). Specifically, social frailty was associated with lower consumption of vegetables, fruits, dairy and lower diet variety in men. Differences were not observed according to social frailty among older women.
Conclusions
Social frailty was associated with poor diet quality in community-dwelling older men, but not in women in Spain. Gender differences in self-care could partly explain this association. Sex-specific interventions are required to minimize the impact of social frailty on diet quality.
{"title":"Sex differences in the association between social frailty and diet quality among older adults in Spain","authors":"Lucía Carcedo-Argüelles , Sara Llamas-Fernández , María del Mar Fernández-Álvarez , Francisco Félix Caballero-Díaz , Fernando Rodríguez-Artalejo , Esther López-García , Alberto Lana","doi":"10.1016/j.jnha.2024.100346","DOIUrl":"10.1016/j.jnha.2024.100346","url":null,"abstract":"<div><h3>Objective</h3><p>The aim was to examine the association between social frailty and diet quality in adults over 65 years of age, and whether results differed by sex.</p></div><div><h3>Design</h3><p>Population-based cross-sectional study using data from the Spanish National Health Survey.</p></div><div><h3>Participants</h3><p>5,071 community-dwelling people ≥65 years from Spain.</p></div><div><h3>Measurements</h3><p>Social frailty was deemed to exist when the person both lived alone and had low social support, measured with the Duke-UNC scale. Diet was assessed with the Spanish Healthy Eating Index (S-HEI), ranging from 0 to 100 points (highest diet quality). Means and 95% confidence intervals of the S-HEI score for each social frailty group were calculated using linear regressions, with socially robust people as reference. Analyses were adjusted for main confounders, including sociodemographic, lifestyle and morbidity variables.</p></div><div><h3>Results</h3><p>There were no differences in the S-HEI adjusted mean of socially frail (74.3 points, 95%CI: 73.4−75.2) compared to socially robust older adults (75.4 points; 95%CI: 75.1−75.7). In sex-stratified analyses, the S-HEI adjusted mean of socially frail men (71.9 points; 95%CI: 70.6−73.2) was lower than robust men (74.8 points; 95%CI: 74.4−75.3). Specifically, social frailty was associated with lower consumption of vegetables, fruits, dairy and lower diet variety in men. Differences were not observed according to social frailty among older women.</p></div><div><h3>Conclusions</h3><p>Social frailty was associated with poor diet quality in community-dwelling older men, but not in women in Spain. Gender differences in self-care could partly explain this association. Sex-specific interventions are required to minimize the impact of social frailty on diet quality.</p></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100346"},"PeriodicalIF":4.3,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004330/pdfft?md5=3e5e73a6b5f9a229cca1e99a708e29ba&pid=1-s2.0-S1279770724004330-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142075919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}