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2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS)最新文献

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Mechanical Tuning of Magnetic Anisotropy 磁各向异性的机械调谐
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056417
M. M. Torunbalci, S. Bhave
This paper demonstrates piezo-mechanical manipulation of magnetic anisotropy in a thin-film CoFeB ferromagnet (FM) via magnetostriction effect. A 20 nm thick CoFeB resistor is fabricated at the base of an AlN cantilever and its magnetization change is detected by measuring anisotropic magnetoresistance (AMR). The uniaxial strain induced in the CoFeB strip by cantilever bending exhibits a 22% change in AMR and rotates the magnetic anisotropy by 20°.
本文演示了利用磁致伸缩效应对CoFeB铁磁薄膜(FM)磁各向异性的压电机械操纵。在AlN悬臂梁底部制作了20nm厚的CoFeB电阻器,并通过测量各向异性磁阻(AMR)来检测其磁化变化。悬臂弯曲引起的CoFeB带材单轴应变的AMR变化22%,磁各向异性旋转20°。
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引用次数: 0
3D Microfluidic Device for Perfusion Culture of Spheroids 球体灌注培养的三维微流控装置
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056442
K. Nishimura, Minghao Nie, S. Takeuchi
We propose a 3D spheroid trapping device featured with a gel formed in the proximity with the spheroids to facilitate spheroid adhesion and perfusion. The device is composed of an upper channel to introduce pre-gel solutions, a bridge region to form a gel and a lower channel to trap a spheroid and perfuse culture media. Due to surface-tension-assisted microfluidic functions, a gel is formed only in the bridge region. The gel performs as an anchoring scaffold for spheroids and enables media perfusion. As a result of spheroid culture, angiogenic vascular sprouts were formed and the sprouts had branched lumen structure. We believe this device will contribute widely to biomedical studies.
我们提出了一种三维球体捕获装置,其特点是在球体附近形成凝胶,以促进球体的粘附和灌注。该装置由用于引入预凝胶溶液的上通道、用于形成凝胶的桥接区域和用于捕获球体并灌注培养基的下通道组成。由于表面张力辅助的微流控功能,凝胶只在桥区形成。凝胶可以作为球体的锚定支架,并使介质灌注成为可能。球型培养形成血管新生芽,芽具有分支管腔结构。我们相信这种装置将对生物医学研究做出广泛贡献。
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引用次数: 1
Comprehensive Analysis and Control of Diffusioosmosis-Driven Ionic Transport Through Interconnected Nanoporous Membranes 纳米孔膜扩散渗透驱动离子传输的综合分析与控制
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056409
Jongwan Lee, Kyunghun Lee, Cong Wang, Dogyeong Ha, Jungyul Park, Taesung Kim
We introduce a micro-/nanofluidic platform enabling the comprehensive analysis and control of diffusioosmosis (DO)-driven ionic transport through a nanochannel network. The nanochannel network is fabricated in the microfluidic channel by forming a membrane via the self-assembly of nanoparticles (i.e., self-assembled particle membrane, SAPM). This fabrication method allows to use various and different nanoparticles so that it is possible to modulate the material properties of the nanochannel network. Using the platform, we analyze the thermal effect on DO-driven ionic transport with various concentrations of electrolyte solutions with the aid of a temperature switching device (TSD).
我们介绍了一种微/纳米流体平台,可以全面分析和控制通过纳米通道网络的扩散渗透(DO)驱动的离子传输。纳米通道网络是通过纳米颗粒的自组装形成膜(即自组装颗粒膜,SAPM)在微流控通道中制备的。这种制造方法允许使用各种不同的纳米颗粒,从而有可能调节纳米通道网络的材料特性。利用该平台,我们借助温度开关器件(TSD)分析了不同浓度电解质溶液对do驱动离子输运的热效应。
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引用次数: 0
One-Step RT-PCR for Detection of Micrornas in Exosomes Using Droplet Microfluidics 利用微滴微流体一步法RT-PCR检测外泌体中的微rna
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056207
Binbin Cui, Chunchen Liu, S. Yao
The dysregulation of the microRNAs, small noncoding RNA around 22 bases, accounts for a wide range of diseases including cancer. However, current methods technologies for of the microRNA the detection and analysis of microRNA are limited to the analysis of bulk exosomes, which fails to depict the heterogeneity of the exosome population as individual vesicles. In this work, we developed a reverse transcription polymerase chain reaction (RT-PCR) protocol on a droplet microfluidic platform. We employed the synthetic hsa-miR-21-5p and exosomes extracted from lung cancer patients in the proof-of-concept experiments. The results indicated that our method can detect as low as a single molecule of microRNA per droplet, which is promising for single exosome microRNA assays.
microrna是一种约22个碱基的小非编码RNA,其失调是包括癌症在内的多种疾病的原因。然而,目前用于检测和分析microRNA的方法技术仅限于对散装外泌体的分析,无法描述外泌体群体作为单个囊泡的异质性。在这项工作中,我们在液滴微流控平台上开发了一种逆转录聚合酶链反应(RT-PCR)方案。我们将合成的hsa-miR-21-5p和从肺癌患者中提取的外泌体用于概念验证实验。结果表明,我们的方法可以检测到每滴低至单个分子的microRNA,这对于单个外泌体microRNA的检测是有希望的。
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引用次数: 4
Locally-Patterned Parylene Membrane Enables Electrical Resistance Measurement for a Cellular Barrier Consisting of < 100 Cells 局部图案聚对二甲苯膜使电阻测量组成的细胞屏障小于100个细胞
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056109
Takumi Yamada, Minghao Nie, A. Shima, Y. Morimoto, S. Takeuchi
We present a system for measuring electrical resistance of a cellular barrier consisting of < 100 cells. We fabricated a parylene membrane with pores etched by photolithography technique and bonded it to Polydimethylsiloxane (PDMS) wells by H2O vapor plasma treatment. This membrane separated the well into two compartments. In our system, since the placement and number of pores were easy to control, the pore-etched part of the membrane was fully covered with cells. Thus, electrical resistance was easily measured using only a small number of cells. As a demonstration of the measurement with the system, Caco-2 cells were seeded on an upper side of the membrane, and the resistance was measured using a volt-ohm meter.
我们提出了一种测量由< 100个细胞组成的细胞屏障的电阻的系统。采用光刻技术制备了带有孔的聚对二甲苯膜,并通过水蒸汽等离子体处理将其与聚二甲基硅氧烷(PDMS)孔结合。这层膜把井分成两个隔室。在我们的系统中,由于孔的位置和数量易于控制,因此膜的孔蚀刻部分被细胞完全覆盖。因此,电阻很容易测量,只使用少量的电池。作为该系统测量的演示,Caco-2细胞被播种在膜的上部,并使用伏特欧姆计测量电阻。
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引用次数: 0
Strong Magnetoelectric Effects of 2–2 Composites Made of AlN Films Grown by Plasma-Enhanced Atomic Layer Deposition on Magnetostrictive Foils for Energy Harvesting Applications 磁致伸缩薄膜上等离子体增强原子层沉积AlN薄膜制备的2-2复合材料的强磁电效应
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056193
Tai Nguyen, Noureddine Adjeroud, S. Glinšek, Y. Fleming, J. Guillot, J. Polesel-Maris
This work presents a novel process of magnetoelectric (ME) stacks composed of a highly (002)-oriented aluminum nitride (AlN) film grown by plasma-enhanced atomic layer deposition (PEALD) on magnetostrictive nickel, iron, and cobalt foils. We report an efficient methodology to process high quality piezoelectric AlN films by PEALD at low temperatures. The effective transverse piezoelectric coefficient $e_{31,f}$ was evaluated to be 0.37 C/m2 for the highly (002)-oriented AlN film. Moreover, by the conformal coating obtained by PEALD, a strong ME coupling of 2.8 V.cm−1. Oe−1 is obtained out of resonance on 2–2 composites of a (002)-oriented AlN film on nickel. This ME device could open a novel way for energy harvesting of microsystems.
这项工作提出了一种新的磁电(ME)堆叠工艺,由高(002)取向的氮化铝(AlN)薄膜组成,该薄膜是通过等离子体增强原子层沉积(PEALD)在磁致伸缩的镍、铁和钴箔上生长的。我们报告了一种在低温下用PEALD加工高质量AlN压电薄膜的有效方法。高(002)取向AlN薄膜的有效横向压电系数e_{31,f}$为0.37 C/m2。此外,通过PEALD获得的保形涂层,强ME耦合为2.8 V.cm−1。在镍基(002)取向AlN膜的2-2复合材料上共振得到了Oe−1。该装置为微系统能量收集开辟了一条新的途径。
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引用次数: 1
Rapid Prototyping of Microactuators by Integrating 3D Printed Polymeric Structures with NiTi Thin Film 集成3D打印聚合物结构与NiTi薄膜的微致动器快速成型
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056231
C. Vélez, Sukjun Kim, M. Babaei, D. Patel, C. Knick, Gabriel L. Smith, S. Bergbreiter
This work demonstrates the first sputtered thin-film nickel-titanium (NiTi) shape-memory alloy (SMA) actuators combined with direct 3D printing of polymeric structures. Resulting actuators are fast to prototype, reliable and stable (up to 5000 cycles), and can utilize complex geometries challenging to achieve with conventional MEMS microfabrication. The actuator design uses 3D printed polymer as the passive layer in unimorph actuators, adding significant versatility to the actuator design. An actuator designed for high force-displacement was fabricated with a $15 mu mathrm{m}$ thick polymer layer and characterized by applying currents up to 18 ma (7.3 mW, producing ∼156°C) resulting in a maximum displacement of $3.3 mu mathrm{m}$ and ∼0.9 mN blocking force. Dynamic operation with falling/rising times of 20.1 ms/9.8 ms and 33.5 Hz maximum operation frequency was also demonstrated.
这项工作展示了第一个与聚合物结构直接3D打印相结合的溅射薄膜镍钛(NiTi)形状记忆合金(SMA)致动器。由此产生的致动器具有快速原型,可靠和稳定(高达5000次循环),并且可以利用传统MEMS微加工难以实现的复杂几何形状。执行器设计使用3D打印聚合物作为单形执行器的被动层,为执行器设计增加了显著的多功能性。采用厚度为15 mu mathm {m}$的聚合物层制备了一种用于高力-位移的致动器,其特点是施加电流高达18 ma (7.3 mW,产生~ 156°C),最大位移为3.3 mu mathm {m}$,阻塞力为~ 0.9 mN。实验还证明了该系统的动态运行速度为20.1 ms/9.8 ms,最大工作频率为33.5 Hz。
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引用次数: 9
Monolithic Integration of Plasmonic Meta-Material Absorber with CMOS-MEMs Infrared Sensor for Responsivity Enhancement and Human Detection Application 等离子体超材料吸收器与CMOS-MEMs红外传感器的集成,用于提高响应性和人体检测应用
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056382
Pen-Sheng Lin, Ting-Wei Shen, Kai-Chieh Chang, W. Fang
This study monolithically integrates a metal-insulator-metal-based (MIM) plasmonic metamaterial absorber (PMA) with a thermoelectric (TE) infrared (IR) sensor using standard TSMC CMOS platform. The proposed design extends the strip-via releasing hole structure in [1] to further integrate MIM absorber with TE IR sensor. Such design exhibits three merits: (1) the line width requirement of MIM absorber is achieved by CMOS process, (2) the absorption peaks of MIM absorbers can be modulated by pattern designs in the epsilon-near-pole region, and (3) the MIM absorbers can be designed to broaden the absorption spectrum of IR sensor. In application, the absorption spectrum of IR sensor is designed within $8-14mu mathrm{m}$ in this study for human detection application. Measurement result demonstrates the integration of MIM absorber and IR sensor can achieve 21% responsivity improvement and the measured absorption spectrum matches with simulation.
本研究采用标准台积电CMOS平台,将金属-绝缘体-金属基(MIM)等离子体超材料吸收体(PMA)与热电(TE)红外(IR)传感器单片集成。所提出的设计扩展了[1]中的带孔释放孔结构,进一步将MIM吸收器与红外传感器集成在一起。这种设计有三个优点:(1)MIM吸收器的线宽要求是通过CMOS工艺实现的;(2)MIM吸收器的吸收峰可以通过在epsilon-近极区域的图案设计来调制;(3)MIM吸收器的设计可以拓宽红外传感器的吸收光谱。在应用方面,本研究将红外传感器的吸收光谱设计在$8-14mu mathrm{m}$范围内,用于人体检测应用。测量结果表明,MIM吸收器与红外传感器集成后,响应率提高21%,测量的吸收光谱与仿真结果吻合。
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引用次数: 4
Electrostatic Micro Mirror Array with Batch-Fabricated Torsion Beam of Silicon Nanowire 批量制备硅纳米线扭转梁的静电微镜阵列
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056252
Tomoya Nakamura, Y. Hirai, O. Tabata, T. Tsuchiya
A new design of arrayed micro mirror device for a high performance spatial light modulator of high resonant frequency, large deflection angle with high mechanical reliability has been proposed. The mirror has $100-mu mathrm{m}$ square plate of $5 mu mathrm{m}$ thick, which is suspended by thin silicon nanowire of about $1 mu mathrm{m}$ thick and wide. The device was fabricated using Bosch process and isotropic plasma etching. We successfully demonstrated array operation of $4times 4$ devices at relatively low actuation voltage (∼20 Vpp) and large mechanical deflection amplitude (∼9°). However, the deviation of vibration amplitude was large among unit resonators. By fitting the frequency response to the Duffing equation we found that self-enhancing actuation force caused by nonlinearity of the vertical combs was a main reason.
为实现高谐振频率、大偏转角、高机械可靠性的高性能空间光调制器,提出了一种新的阵列微镜器件设计方案。镜子有$100- mu mathm {m}$厚的$5 mu mathm {m}$方板,由约$1 mu mathm {m}$粗和宽的细硅纳米线悬浮。该器件采用博世工艺和各向同性等离子体刻蚀技术制备。我们成功地演示了在相对低的驱动电压(~ 20 Vpp)和大的机械偏转幅度(~ 9°)下,$4 × 4$器件的阵列操作。但单元谐振器之间的振动幅值偏差较大。通过对Duffing方程的频响拟合,发现垂直梳子非线性引起的自增强作动力是主要原因。
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引用次数: 1
Investigating Long-Term Stability of Wide Bandwidth Surface Acoustic Waves Gyroscopes Using a Monolithically Integrated Micro-Oven 用单片集成微烤箱研究宽带表面声波陀螺仪的长期稳定性
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056180
A. Mahmoud, T. Mukherjee, G. Piazza
This paper is the first to investigate the long-term stability of Surface Acoustic Wave Gyroscopes (SAWG) using an ovenized control system. Monolithic integration of a MEMS heater adjacent to SAW devices on Lithium Niobate over insulator substrate (LNOI) tightly couples frequency-based temperature detection with heating for temperature and frequency stabilization. This first prototype demonstrates the ability to minimize the temperature variations of the SAWG to below $pm 10 mumathrm{K}$ and stabilize the SAWG resonance frequency to ±0.2 ppm. This approach thus eliminates the thermal drift in a SAWG and enables the development of a new generation of MEMS-based gyroscopes with long-term stability.
本文首次研究了表面声波陀螺仪(SAWG)的长期稳定性。在绝缘体衬底上的铌酸锂(LNOI)上,MEMS加热器的单片集成与SAW器件相邻,将基于频率的温度检测与加热紧密耦合,以实现温度和频率稳定。第一个原型证明了将SAWG的温度变化最小化到$pm 10 mu maththrm {K}$以下的能力,并将SAWG的谐振频率稳定在±0.2 ppm。因此,这种方法消除了SAWG中的热漂移,并使新一代基于mems的陀螺仪具有长期稳定性。
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引用次数: 3
期刊
2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS)
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