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2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS)最新文献

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Fully Additively Manufactured, Nanostructured, Miniature Ionic Liquid Electrospray Sources 完全增材制造,纳米结构,微型离子液体电喷雾源
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056405
D. Melo-Máximo, L. Velásquez-García
We report the design, fabrication, and characterization of the first fully additively manufactured ionic liquid electrospray sources in the literature. The devices are diodes composed of an emitting electrode and an extractor electrode: the emitting electrode is a monolithic array of digital light projection (DLP)-printed solid, conical, polymeric needles covered by a conformal layer of hydrothermally grown zinc oxide (ZnO) nanowires as wicking material, while the extractor electrode is a stainless-steel plate with an array of apertures that matches the pattern of the array of needles. Devices with 1, 7, and 19 2.5 mm-long, $sim 100 mu mathrm{m}$ tip diameter needles (2.1 mm pitch), covered with a forest of $1.2 mu mathrm{m}$ long, 150 nm diameter ZnO nanowires, were designed, fabricated, and characterized in vacuum (∼10−6 Torr) in a triode configuration (i.e. with an external collector electrode) in the negative polarity. Devices emit up to ∼86% of the current produced by the emitting electrode, and attain peremitter currents as high as $15 mu mathrm{A}$ –a tenfold larger than cleanroom-microfabricated counterparts.
我们报道了文献中第一个完全增材制造的离子液体电喷雾源的设计、制造和表征。该装置是由发射电极和提取电极组成的二极管:发射电极是数字光投影(DLP)印刷的固体锥形聚合物针的单片阵列,上面覆盖着一层水热生长的氧化锌(ZnO)纳米线作为吸芯材料,而提取电极是一个不锈钢板,上面有一系列与针阵列相匹配的孔。设计、制造了具有1、7和19个2.5 mm长,$sim 100 mu mathrm{m}$针尖直径(2.1 mm节距)的器件,并在负极三极结构(即具有外部集电极)的真空(~ 10−6 Torr)中覆盖了$1.2 mu mathrm{m}$长,150 nm直径的ZnO纳米线。器件发射高达~ 86% of the current produced by the emitting electrode, and attain peremitter currents as high as $15 mu mathrm{A}$ –a tenfold larger than cleanroom-microfabricated counterparts.
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引用次数: 1
Micro-Acoustic Quad Circulator with Self-Interference Cancellation 具有自干扰消除的微声四元环行器
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056324
Yao Yu, M. Rinaldi
In this paper, a micro-acoustic RF circulator with novel “quad” configuration is reported. Four micro-acoustic filters are periodically modulated by RF switches to break the reciprocity. The use of high-Q micro-acoustic filters significantly reduces the modulation frequency (14 MHz) compared to previous demonstrations based on transmission lines (e.g., 333 MHz in [1]). The low modulation frequency translates to an ultra-low power consumption (202 uW, 3600 times smaller than [1]) and one of the highest linearity ($mathrm{P}1mathrm{dB}=31 mathrm{dBm}$) reported for magnet-free circulators. Furthermore, compared to the more conventional differential configuration, this quad configuration shows advantages in terms of intermodulation products (IMPs) suppression for all the in-band IMPs, guaranteeing a pseudo-linear-time-invariant (pseudo-LTI) operation. Furthermore, the isolation of the circulator is further improved by an additional cancellation circuit, achieving more than 50 dB of isolation in a 10MHz bandwidth (BW). This high level of isolation enables the use of this magnet-free circulator in full-duplex radio, which requires large level of self-interference suppression between the transmitter and the receiver nodes.
本文报道了一种新型“四边形”结构的微声射频环行器。四个微声滤波器由射频开关周期性调制以打破互易性。与之前基于传输线的演示(例如[1]中的333 MHz)相比,高q微声滤波器的使用显著降低了调制频率(14 MHz)。低调制频率意味着超低功耗(202 uW,比[1]小3600倍)和最高线性度之一($ mathm {P}1 mathm {dB}=31 mathm {dBm}$)。此外,与更传统的差分配置相比,这种四组配置在所有带内imp的互调产物(imp)抑制方面显示出优势,保证了伪线性时不变(伪lti)操作。此外,通过额外的抵消电路进一步提高了环行器的隔离度,在10MHz带宽(BW)下实现了超过50 dB的隔离。这种高水平的隔离使得在全双工无线电中使用这种无磁环行器成为可能,这需要在发送器和接收器节点之间进行高水平的自干扰抑制。
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引用次数: 3
Strong Magnetoelectric Effects of 2–2 Composites Made of AlN Films Grown by Plasma-Enhanced Atomic Layer Deposition on Magnetostrictive Foils for Energy Harvesting Applications 磁致伸缩薄膜上等离子体增强原子层沉积AlN薄膜制备的2-2复合材料的强磁电效应
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056193
Tai Nguyen, Noureddine Adjeroud, S. Glinšek, Y. Fleming, J. Guillot, J. Polesel-Maris
This work presents a novel process of magnetoelectric (ME) stacks composed of a highly (002)-oriented aluminum nitride (AlN) film grown by plasma-enhanced atomic layer deposition (PEALD) on magnetostrictive nickel, iron, and cobalt foils. We report an efficient methodology to process high quality piezoelectric AlN films by PEALD at low temperatures. The effective transverse piezoelectric coefficient $e_{31,f}$ was evaluated to be 0.37 C/m2 for the highly (002)-oriented AlN film. Moreover, by the conformal coating obtained by PEALD, a strong ME coupling of 2.8 V.cm−1. Oe−1 is obtained out of resonance on 2–2 composites of a (002)-oriented AlN film on nickel. This ME device could open a novel way for energy harvesting of microsystems.
这项工作提出了一种新的磁电(ME)堆叠工艺,由高(002)取向的氮化铝(AlN)薄膜组成,该薄膜是通过等离子体增强原子层沉积(PEALD)在磁致伸缩的镍、铁和钴箔上生长的。我们报告了一种在低温下用PEALD加工高质量AlN压电薄膜的有效方法。高(002)取向AlN薄膜的有效横向压电系数e_{31,f}$为0.37 C/m2。此外,通过PEALD获得的保形涂层,强ME耦合为2.8 V.cm−1。在镍基(002)取向AlN膜的2-2复合材料上共振得到了Oe−1。该装置为微系统能量收集开辟了一条新的途径。
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引用次数: 1
Locally-Patterned Parylene Membrane Enables Electrical Resistance Measurement for a Cellular Barrier Consisting of < 100 Cells 局部图案聚对二甲苯膜使电阻测量组成的细胞屏障小于100个细胞
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056109
Takumi Yamada, Minghao Nie, A. Shima, Y. Morimoto, S. Takeuchi
We present a system for measuring electrical resistance of a cellular barrier consisting of < 100 cells. We fabricated a parylene membrane with pores etched by photolithography technique and bonded it to Polydimethylsiloxane (PDMS) wells by H2O vapor plasma treatment. This membrane separated the well into two compartments. In our system, since the placement and number of pores were easy to control, the pore-etched part of the membrane was fully covered with cells. Thus, electrical resistance was easily measured using only a small number of cells. As a demonstration of the measurement with the system, Caco-2 cells were seeded on an upper side of the membrane, and the resistance was measured using a volt-ohm meter.
我们提出了一种测量由< 100个细胞组成的细胞屏障的电阻的系统。采用光刻技术制备了带有孔的聚对二甲苯膜,并通过水蒸汽等离子体处理将其与聚二甲基硅氧烷(PDMS)孔结合。这层膜把井分成两个隔室。在我们的系统中,由于孔的位置和数量易于控制,因此膜的孔蚀刻部分被细胞完全覆盖。因此,电阻很容易测量,只使用少量的电池。作为该系统测量的演示,Caco-2细胞被播种在膜的上部,并使用伏特欧姆计测量电阻。
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引用次数: 0
One-Step RT-PCR for Detection of Micrornas in Exosomes Using Droplet Microfluidics 利用微滴微流体一步法RT-PCR检测外泌体中的微rna
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056207
Binbin Cui, Chunchen Liu, S. Yao
The dysregulation of the microRNAs, small noncoding RNA around 22 bases, accounts for a wide range of diseases including cancer. However, current methods technologies for of the microRNA the detection and analysis of microRNA are limited to the analysis of bulk exosomes, which fails to depict the heterogeneity of the exosome population as individual vesicles. In this work, we developed a reverse transcription polymerase chain reaction (RT-PCR) protocol on a droplet microfluidic platform. We employed the synthetic hsa-miR-21-5p and exosomes extracted from lung cancer patients in the proof-of-concept experiments. The results indicated that our method can detect as low as a single molecule of microRNA per droplet, which is promising for single exosome microRNA assays.
microrna是一种约22个碱基的小非编码RNA,其失调是包括癌症在内的多种疾病的原因。然而,目前用于检测和分析microRNA的方法技术仅限于对散装外泌体的分析,无法描述外泌体群体作为单个囊泡的异质性。在这项工作中,我们在液滴微流控平台上开发了一种逆转录聚合酶链反应(RT-PCR)方案。我们将合成的hsa-miR-21-5p和从肺癌患者中提取的外泌体用于概念验证实验。结果表明,我们的方法可以检测到每滴低至单个分子的microRNA,这对于单个外泌体microRNA的检测是有希望的。
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引用次数: 4
Dandelion Flower Like, APTES Functionalized Gallium Nitirde Microsphere for Fluorescence Detection of Bovine Serum Albumin Protein 蒲公英花状APTES功能化氮化镓微球荧光检测牛血清白蛋白
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056337
Manimuthu Veerappan, Fei Wang
In this abstract, we present GaN microsphere with dandelion flower-like morphology and high crystalline quality, synthesized using the optimized ammonothermal-ammonolysis hybrid method. The GaN micro-spherical flower are further functionalized with APTES for immobilization of biomolecules. Therefore, GaN microsphere has been first ever utilized for BSA protein biosensor. We studied the influence of the ammonolysis temperature on the BSA sensing performance of the GaN based protein biosensors. By varying the band-gap of the material, APTES modified GaN microspheres have demonstrated tunable blue and green fluorescent emission from BSA, which shows promising application for protein detection.
本文采用优化后的氨热-氨解混合方法合成了具有蒲公英花状形貌和高结晶质量的氮化镓微球。用APTES进一步功能化GaN微球形花,用于固定化生物分子。因此,氮化镓微球首次被用于牛血清白蛋白生物传感器。我们研究了氨解温度对氮化镓蛋白生物传感器感知牛血清白蛋白性能的影响。通过改变材料的带隙,APTES修饰的GaN微球显示出可调谐的BSA蓝色和绿色荧光发射,这在蛋白质检测中具有广阔的应用前景。
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引用次数: 0
Integrated Phosphate and pH Sensing System for Water Quality Monitoring 用于水质监测的综合磷酸盐和pH传感系统
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056230
Renuka Bowrothu, T. Schumann, Hae-in Kim, Kyoung-Tae Kim, S. Hwang, Yoonseok Lee, Y. Yoon
Cobalt (Co) ion selective electrode (ISE) has been studied for selective phosphate detection. As the electromotive force (EMF) response of this electrode to phosphate is affected by surrounding pH conditions, it has not been readily utilized for in-situ monitoring. In this work, we present an integrated Co based phosphate and antimony (Sb) based pH sensing system, which enables us to monitor precise phosphorous concentration taking into account a local pH level in aqueous solution. Platinum is used as the reference electrode. An extremely broad sensing range of phosphate concentration with 9 orders of magnitude concentration ranging between $5times 10^{-3}$ to $5times 10^{-12}$ M is reported. The sensing sensitive of 5 pM is one of the best reported in this kind of sensors in literature. Also, simultaneous detection of pH and phosphate concentration is presented using integrated wireless Bluetooth module. The total area of the fabricated sensor is 4 cm2.
研究了钴离子选择电极(ISE)对磷酸盐的选择性检测。由于该电极对磷酸盐的电动势(EMF)响应受周围pH条件的影响,它还不容易用于现场监测。在这项工作中,我们提出了一个集成的基于Co的磷酸盐和锑(Sb)的pH传感系统,该系统使我们能够在考虑水溶液中局部pH值的情况下精确监测磷浓度。铂被用作参比电极。在5 × 10^{-3}$至5 × 10^{-12}$ M之间,具有9个数量级的极宽的磷酸盐浓度传感范围。5pm的传感灵敏度是目前文献中报道得最好的该类传感器之一。同时,利用集成的无线蓝牙模块实现了pH和磷酸盐浓度的同时检测。所制传感器的总面积为4平方厘米。
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引用次数: 1
Micromachined Mass-Sensitive and Capacitive Chemical Multisensor Using Single Polymeric Sensing Film 基于单聚合物传感膜的微机械质量敏感和电容化学多传感器
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056216
S. Schwartz, O. Brand, L. Beardslee
We present a novel micromachined chemical multisensor that simultaneously detects mass and dielectric property changes in the same polymeric sensing film. The multisensor is comprised of a cantilever-type, mass-sensitive resonant sensor with a semicircular annulus and an embedded on-resonator interdigitated electrode structure for capacitive sensing. The resonant chemical sensor utilizes a high-Q in-plane resonance mode enabling sub-parts per million limits of detection for volatile organic compounds. The embedded capacitive sensor enables the discrimination between toluene and methanol by evaluating the ratio between the mass-sensitive and capacitive sensor signal.
我们提出了一种新型的微机械化学多传感器,可以同时检测同一聚合物传感膜中质量和介电性质的变化。该多传感器由悬臂式、带半圆形环的质量敏感谐振传感器和用于电容传感的嵌入式谐振腔间指电极结构组成。谐振式化学传感器采用高q平面内共振模式,能够对挥发性有机化合物进行百万分之一的检测限。嵌入式电容式传感器通过评估质量敏感和电容式传感器信号之间的比率来区分甲苯和甲醇。
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引用次数: 1
In-Plane Mode Resonant Cantilever Sensor to Detect Kinetic/Thermodynamic Parameters for Aptamer-Ligand Binding 平面模式共振悬臂传感器检测适配体-配体结合动力学/热力学参数
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056123
Xuefeng Wang, Yarong Cheng, Shengran Cai, P. Xu, Ying Chen, Haitao Yu, Xinxin Li
An in-plane mode resonant cantilever sensor working in solution is developed for detecting physicochemical parameters of aptamer-ligand binding. The cantilever body is enclosed inside a hydrophobic parylene shell, and a ring-shaped hydrophobic slit is designed to prevent the solution leak inside the shell, allowing the cantilever structure keeps high-Q resonance in air while the binding sensing pool is exposed to aqueous solution for the biological binding. The resonant cantilever continuously records the frequency-shift according to the binding induced mass change on the cantilever. The frequency signal is useful for revealing kinetic/thermodynamic mechanism of the interface binding by fitting the detected sensorgram with classic equations. This detection strategy is label-free and calibration-free, with all the measurement completed using one device to avoid system error.
研制了一种用于检测适配体与配体结合的物理化学参数的平面内谐振悬臂式传感器。悬臂体封闭在疏水性聚二甲苯壳体内,并设计环状疏水狭缝防止壳体内溶液泄漏,使悬臂结构在空气中保持高q共振,同时结合传感池暴露于水溶液中进行生物结合。谐振悬臂梁根据束缚引起的悬臂梁上的质量变化连续记录频率的变化。频率信号通过将检测到的传感器图与经典方程拟合,有助于揭示界面结合的动力学/热力学机制。这种检测策略是无标签和校准,所有的测量完成使用一个设备,以避免系统误差。
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引用次数: 0
Electrostatic Micro Mirror Array with Batch-Fabricated Torsion Beam of Silicon Nanowire 批量制备硅纳米线扭转梁的静电微镜阵列
Pub Date : 2020-01-01 DOI: 10.1109/MEMS46641.2020.9056252
Tomoya Nakamura, Y. Hirai, O. Tabata, T. Tsuchiya
A new design of arrayed micro mirror device for a high performance spatial light modulator of high resonant frequency, large deflection angle with high mechanical reliability has been proposed. The mirror has $100-mu mathrm{m}$ square plate of $5 mu mathrm{m}$ thick, which is suspended by thin silicon nanowire of about $1 mu mathrm{m}$ thick and wide. The device was fabricated using Bosch process and isotropic plasma etching. We successfully demonstrated array operation of $4times 4$ devices at relatively low actuation voltage (∼20 Vpp) and large mechanical deflection amplitude (∼9°). However, the deviation of vibration amplitude was large among unit resonators. By fitting the frequency response to the Duffing equation we found that self-enhancing actuation force caused by nonlinearity of the vertical combs was a main reason.
为实现高谐振频率、大偏转角、高机械可靠性的高性能空间光调制器,提出了一种新的阵列微镜器件设计方案。镜子有$100- mu mathm {m}$厚的$5 mu mathm {m}$方板,由约$1 mu mathm {m}$粗和宽的细硅纳米线悬浮。该器件采用博世工艺和各向同性等离子体刻蚀技术制备。我们成功地演示了在相对低的驱动电压(~ 20 Vpp)和大的机械偏转幅度(~ 9°)下,$4 × 4$器件的阵列操作。但单元谐振器之间的振动幅值偏差较大。通过对Duffing方程的频响拟合,发现垂直梳子非线性引起的自增强作动力是主要原因。
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引用次数: 1
期刊
2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS)
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