Pub Date : 2025-12-29DOI: 10.1007/s44192-025-00325-z
Linda Liebenberg, Jackie Sanders, Jayne Mercier
Globally, there is increasing need to address the burden of mental illness on populations, including youth, and increasing recognition of the role of social determinants on mental health. The study of resilience, as an ecological process of individual and community resource mobilisation in the face of adversity, is a promising lens through which to understand culturally and contextually relevant factors that enhance or inhibit mental wellbeing. This paper reports on a validation of a reduced, 2-factor, 17-item form of the child and youth resilience measure (CYRM-28) on a population of youth in Aotearoa (New Zealand) who were involved in multiple service systems, including child and adolescent mental health services. It builds on previous work which validated the full 28-item scale. It responds to needs articulated by researchers and service providers for a shortened version of the CYRM-28 that reduces assessment burdens on youth and clinicians. The reduced form may be helpful in mental health settings to quickly understand the resilience resources around vulnerable youth and support interventions that build on strengths and directly address areas where resources are missing.
{"title":"Validation of a reduced version of the child and youth resilience measure (CYRM-28) for public health use in Aotearoa New Zealand.","authors":"Linda Liebenberg, Jackie Sanders, Jayne Mercier","doi":"10.1007/s44192-025-00325-z","DOIUrl":"10.1007/s44192-025-00325-z","url":null,"abstract":"<p><p>Globally, there is increasing need to address the burden of mental illness on populations, including youth, and increasing recognition of the role of social determinants on mental health. The study of resilience, as an ecological process of individual and community resource mobilisation in the face of adversity, is a promising lens through which to understand culturally and contextually relevant factors that enhance or inhibit mental wellbeing. This paper reports on a validation of a reduced, 2-factor, 17-item form of the child and youth resilience measure (CYRM-28) on a population of youth in Aotearoa (New Zealand) who were involved in multiple service systems, including child and adolescent mental health services. It builds on previous work which validated the full 28-item scale. It responds to needs articulated by researchers and service providers for a shortened version of the CYRM-28 that reduces assessment burdens on youth and clinicians. The reduced form may be helpful in mental health settings to quickly understand the resilience resources around vulnerable youth and support interventions that build on strengths and directly address areas where resources are missing.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"201"},"PeriodicalIF":2.7,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12748470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145851827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-28DOI: 10.1007/s44192-025-00361-9
Matthew S Johnston, Rosemary Ricciardelli, Marina Carbonell, Sahar Dorniani, Tamara L Taillieu, Seamus Keiley, Tracie O Afifi
Amongst the correctional worker population, a wide range of demographic characteristics shape mental health outcomes, organizational stigma, and treatment-seeking, including gender and/or sex differences. Yet, considerations of the relationship between gender and especially sex and mental health in correctional systems internationally remain understudied and have not been investigated on a national scale. In the current national study, we quantitatively analyze Canadian provincial and territorial correctional workers' (n = 3,740) sex correlates with other sociodemographic variables, and examine the prevalence of potentially psychologically traumatic events (PPTEs), correctional-specific PPTEs, occupational stressors, suicide-related behaviour (ideation, plan, and attempt), and several mental health disorders. Survey findings indicate statistically significant sex differences in exposure to all types of PPTEs, with the exception of captivity and life-threatening illness or injury. Males reported higher odds of being exposed to all types of PPTEs than females, with the exception of sexual assault and other unwanted or uncomfortable sexual experiences, which females had higher odds of experiencing. Statistically significant sex differences were also evident in exposure to all types of correctional-specific PPTEs, except for instances where a person died while under their supervision. Other significant relationships found are discussed and reiterate the necessity of incorporating concerns for gender and/or sex equality and balance in correctional settings into mental health training regimen, as well as highlight several areas for future research.
{"title":"A national study of sex and mental health considerations among provincial and territorial correctional workers in Canada.","authors":"Matthew S Johnston, Rosemary Ricciardelli, Marina Carbonell, Sahar Dorniani, Tamara L Taillieu, Seamus Keiley, Tracie O Afifi","doi":"10.1007/s44192-025-00361-9","DOIUrl":"10.1007/s44192-025-00361-9","url":null,"abstract":"<p><p>Amongst the correctional worker population, a wide range of demographic characteristics shape mental health outcomes, organizational stigma, and treatment-seeking, including gender and/or sex differences. Yet, considerations of the relationship between gender and especially sex and mental health in correctional systems internationally remain understudied and have not been investigated on a national scale. In the current national study, we quantitatively analyze Canadian provincial and territorial correctional workers' (n = 3,740) sex correlates with other sociodemographic variables, and examine the prevalence of potentially psychologically traumatic events (PPTEs), correctional-specific PPTEs, occupational stressors, suicide-related behaviour (ideation, plan, and attempt), and several mental health disorders. Survey findings indicate statistically significant sex differences in exposure to all types of PPTEs, with the exception of captivity and life-threatening illness or injury. Males reported higher odds of being exposed to all types of PPTEs than females, with the exception of sexual assault and other unwanted or uncomfortable sexual experiences, which females had higher odds of experiencing. Statistically significant sex differences were also evident in exposure to all types of correctional-specific PPTEs, except for instances where a person died while under their supervision. Other significant relationships found are discussed and reiterate the necessity of incorporating concerns for gender and/or sex equality and balance in correctional settings into mental health training regimen, as well as highlight several areas for future research.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":" ","pages":"19"},"PeriodicalIF":2.7,"publicationDate":"2025-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12858714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145851843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of hypnosis on psychological distress in female university students with premenstrual syndrome.","authors":"Sousan Heydarpour, Fatemeh Heydarpour, Fateme Dehghan, Yousef Torabi","doi":"10.1007/s44192-025-00355-7","DOIUrl":"10.1007/s44192-025-00355-7","url":null,"abstract":"","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":" ","pages":"18"},"PeriodicalIF":2.7,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-24DOI: 10.1007/s44192-025-00312-4
B Baumberger, L Batey, P Hashemi
Three main theories of depression have been developed: the monoamine, plasticity and inflammation theories. While each theory has been bolstered by decades of excellent scientific evidence, individually each idea falls short for developing universally effective treatments for depression. In this perspective, we present the history and development of each theory and discuss the therapies that follow each hypothesis. We provide a unique perspective by highlighting the historical evolution, clinical implications, and the nexus between the three hypotheses. We emphasise how the theories are mutually inclusive and influence one another and are smaller parts of a larger puzzle. We suggest that future therapies should involve all three: ze: monoamines, plasticity and inflammation.
{"title":"How three different theories of depression converge at inflammation.","authors":"B Baumberger, L Batey, P Hashemi","doi":"10.1007/s44192-025-00312-4","DOIUrl":"10.1007/s44192-025-00312-4","url":null,"abstract":"<p><p>Three main theories of depression have been developed: the monoamine, plasticity and inflammation theories. While each theory has been bolstered by decades of excellent scientific evidence, individually each idea falls short for developing universally effective treatments for depression. In this perspective, we present the history and development of each theory and discuss the therapies that follow each hypothesis. We provide a unique perspective by highlighting the historical evolution, clinical implications, and the nexus between the three hypotheses. We emphasise how the theories are mutually inclusive and influence one another and are smaller parts of a larger puzzle. We suggest that future therapies should involve all three: ze: monoamines, plasticity and inflammation.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"197"},"PeriodicalIF":2.7,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12738436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><p>Alzheimer's disease is a brain condition that slowly erodes a person's memory and cognitive abilities. It is caused by damage to brain cell, particularly in the hippocampus, a region crucial for memory. By 2050 worldwide no. of AD is going increases. Various therapeutic strategies have been explored for AD. The use of herbal products is one of the treatment regimens for AD. In this study, we examined how a herbal extract from Momordica dioica could potentially protect Wistar rats from AD caused by Aluminum chloride. Aluminum chloride (AlCl<sub>3</sub>) is widely used in preclinical studies to induce Alzheimer-like symptoms, as chronic exposure is known to promote oxidative stress, neuroinflammation, and cholinergic dysfunction-hallmarks of Alzheimer's disease pathology. A total of 86 Wistar rats were randomly assigned to nine experimental groups (n = 6-10 per group), including a normal control group and an Alzheimer's disease (AD) model group. One group treated with Donepezil (2.05 mg/kg), three groups treated with different doses of herbal extract of Momordica dioica (100, 200 and 400 mg/kg), and three groups treated with a combination of Donepezil and herbal extract of Momordica dioica (std + 100, std + 200 and std + 400 mg/kg). The aluminum chloride (17 mg/kg, p.o) was administered once daily for 7 days to induce AD. From the 8th day onward, the herbal extract of Momordica dioica was administered orally for 21 consecutive days at doses of 100, 200, and 400 mg/kg to groups 4, 5, and 6 respectively, as well as in combination with Donepezil (2.05 mg/kg) in groups 7, 8, and 9. This brought the total duration of the study to 28 days." Elevated Plus Maze and Forced Swim test was used for the behavioral assessment. After that, brain samples were collected for biochemical analysis. Herbal Extract significantly improved AlCl3-induced behavioral impairments and cognition deficits in Forced Swim Test, Elevated Plus Maze Test significantly with high dose. Then, herbal extract of Momordica dioica facilitated cholinergic activity via inhibiting acetylcholinesterase (AChE) activity. Besides, herbal extract of Momordica dioica decreased lipid peroxidation level & Nitrite level but enhanced levels of glutathione, Succinate dehydrogenase, Catalase and superoxide dismutase and results are more convincing with high dose. Histopathological analysis further confirmed reduced neuronal degeneration and better preservation of brain architecture, especially at higher doses of the herbal extract." The results suggested that herbal extract of Momordica dioica ameliorated AlCl3-induced cognitive and memory impairments, possibly through regulating AChE activity, suppressing oxidative stress. The herbal extract of Momordica dioica significantly improved behavioral impairments and cognition deficits, particularly at high doses. It facilitates cholinergic activity by inhibiting AChE activity and reduced oxidative stress. Overall, the conclusion states that the herbal ex
{"title":"Evaluation of the neuroprotective activity of Momordica dioica against aluminum chloride (AlCl3)-Induced alzheimer's disease in Wistar rats.","authors":"Vrushali Neve, Sayyed Saqlain, Addepalli Veeranjaneyulu, Pawan Karwa, Harshad Kapare, Ketaki Yeralkar","doi":"10.1007/s44192-025-00243-0","DOIUrl":"10.1007/s44192-025-00243-0","url":null,"abstract":"<p><p>Alzheimer's disease is a brain condition that slowly erodes a person's memory and cognitive abilities. It is caused by damage to brain cell, particularly in the hippocampus, a region crucial for memory. By 2050 worldwide no. of AD is going increases. Various therapeutic strategies have been explored for AD. The use of herbal products is one of the treatment regimens for AD. In this study, we examined how a herbal extract from Momordica dioica could potentially protect Wistar rats from AD caused by Aluminum chloride. Aluminum chloride (AlCl<sub>3</sub>) is widely used in preclinical studies to induce Alzheimer-like symptoms, as chronic exposure is known to promote oxidative stress, neuroinflammation, and cholinergic dysfunction-hallmarks of Alzheimer's disease pathology. A total of 86 Wistar rats were randomly assigned to nine experimental groups (n = 6-10 per group), including a normal control group and an Alzheimer's disease (AD) model group. One group treated with Donepezil (2.05 mg/kg), three groups treated with different doses of herbal extract of Momordica dioica (100, 200 and 400 mg/kg), and three groups treated with a combination of Donepezil and herbal extract of Momordica dioica (std + 100, std + 200 and std + 400 mg/kg). The aluminum chloride (17 mg/kg, p.o) was administered once daily for 7 days to induce AD. From the 8th day onward, the herbal extract of Momordica dioica was administered orally for 21 consecutive days at doses of 100, 200, and 400 mg/kg to groups 4, 5, and 6 respectively, as well as in combination with Donepezil (2.05 mg/kg) in groups 7, 8, and 9. This brought the total duration of the study to 28 days.\" Elevated Plus Maze and Forced Swim test was used for the behavioral assessment. After that, brain samples were collected for biochemical analysis. Herbal Extract significantly improved AlCl3-induced behavioral impairments and cognition deficits in Forced Swim Test, Elevated Plus Maze Test significantly with high dose. Then, herbal extract of Momordica dioica facilitated cholinergic activity via inhibiting acetylcholinesterase (AChE) activity. Besides, herbal extract of Momordica dioica decreased lipid peroxidation level & Nitrite level but enhanced levels of glutathione, Succinate dehydrogenase, Catalase and superoxide dismutase and results are more convincing with high dose. Histopathological analysis further confirmed reduced neuronal degeneration and better preservation of brain architecture, especially at higher doses of the herbal extract.\" The results suggested that herbal extract of Momordica dioica ameliorated AlCl3-induced cognitive and memory impairments, possibly through regulating AChE activity, suppressing oxidative stress. The herbal extract of Momordica dioica significantly improved behavioral impairments and cognition deficits, particularly at high doses. It facilitates cholinergic activity by inhibiting AChE activity and reduced oxidative stress. Overall, the conclusion states that the herbal ex","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"198"},"PeriodicalIF":2.7,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12738438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-24DOI: 10.1007/s44192-025-00335-x
Nasar Ahmad Shayan, Ali Rahimi, Abdul Momen Waseq, Osman Dag, Hilal Özcebe
Objective: This study aimed to evaluate the validity and reliability of the Dari-translated Depression, Anxiety, and Stress Scale-42 (DASS-42) in university students in Herat, Afghanistan.
Methods: A cross-sectional study was conducted from August to November 2022 with 1000 undergraduate students at Herat University. Participants completed a self-reported Dari-translated DASS-42 questionnaire. Confirmatory Factor Analysis (CFA) was employed to assess the scale's factor structure, and internal consistency was evaluated using Cronbach's alpha. The test-retest reliability was also examined over a 2-3 week interval.
Results: The CFA results indicated a good fit for the three-factor model, with RMSEA = 0.04 and CFI = 0.919, confirming the construct validity of the scale. Internal consistency was high, with Cronbach's alpha values of 0.867, 0.831, and 0.848 for depression, anxiety, and stress, respectively. The test-retest reliability coefficients for depression, anxiety, and stress were 0.956, 0.923, and 0.951, respectively. Additionally, DASS-42 showed significant correlations with other established mental health measures, indicating good convergent validity.
Conclusion: The DASS-42 is a valid and reliable instrument for assessing depression, anxiety, and stress among university students in Herat, Brazil. This comprehensive validation addresses previous limitations and supports the use of the scale in both clinical and non-clinical settings for early detection and intervention. Future research should explore the scale's applicability in more diverse Afghan populations and incorporate longitudinal designs to validate its predictive validity further.
{"title":"Translation, validation and reliability of depression, anxiety, and stress 42 (DASS-42) among Herat University students.","authors":"Nasar Ahmad Shayan, Ali Rahimi, Abdul Momen Waseq, Osman Dag, Hilal Özcebe","doi":"10.1007/s44192-025-00335-x","DOIUrl":"10.1007/s44192-025-00335-x","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the validity and reliability of the Dari-translated Depression, Anxiety, and Stress Scale-42 (DASS-42) in university students in Herat, Afghanistan.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from August to November 2022 with 1000 undergraduate students at Herat University. Participants completed a self-reported Dari-translated DASS-42 questionnaire. Confirmatory Factor Analysis (CFA) was employed to assess the scale's factor structure, and internal consistency was evaluated using Cronbach's alpha. The test-retest reliability was also examined over a 2-3 week interval.</p><p><strong>Results: </strong>The CFA results indicated a good fit for the three-factor model, with RMSEA = 0.04 and CFI = 0.919, confirming the construct validity of the scale. Internal consistency was high, with Cronbach's alpha values of 0.867, 0.831, and 0.848 for depression, anxiety, and stress, respectively. The test-retest reliability coefficients for depression, anxiety, and stress were 0.956, 0.923, and 0.951, respectively. Additionally, DASS-42 showed significant correlations with other established mental health measures, indicating good convergent validity.</p><p><strong>Conclusion: </strong>The DASS-42 is a valid and reliable instrument for assessing depression, anxiety, and stress among university students in Herat, Brazil. This comprehensive validation addresses previous limitations and supports the use of the scale in both clinical and non-clinical settings for early detection and intervention. Future research should explore the scale's applicability in more diverse Afghan populations and incorporate longitudinal designs to validate its predictive validity further.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"199"},"PeriodicalIF":2.7,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12738504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A pilot randomized controlled trial to evaluate the efficacy of transitional care interventions to improve mental health outcomes using a continuity of care approach for individuals with severe mental illness.","authors":"Irasangappa Mudakavi, Sreevani Rentala, Naresh Nebhinani","doi":"10.1007/s44192-025-00329-9","DOIUrl":"10.1007/s44192-025-00329-9","url":null,"abstract":"","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"196"},"PeriodicalIF":2.7,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12722612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145806577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-21DOI: 10.1007/s44192-025-00327-x
Asmaa Mohammad Ahmad Mohammad, Rabab Ahmed Abd El-Hai Hammad, Noha M Elghazally
Background: Onychophagia, or chronic nail biting, is a common body-focused repetitive behaviour often associated with psychological stress, anxiety, and perfectionism. Medical students may be at increased risk due to sustained mental and emotional pressures.
Objectives: To assess the prevalence of onychophagia, identify associated risk factors, and examine the relationship between perceived stress levels and the frequency or severity of nail biting among medical students at Tanta University in Egypt.
Methods: A cross-sectional study was conducted among 330 undergraduate students using a structured self-administered questionnaire comprising sociodemographic data, onychophagia-related items, and the Perceived Stress Scale (PSS).
Results: 57.3% of the students were actively practicing onychophagia, and it was reported more often among males (63.5%) than females (36.5%), but the difference was not statistically significant (p = 0.134). Among participants with onychophagia (n = 189), 18 (9.5%) were smokers, 63 (33.3%) reported a positive family history, and 30 (15.9%) reported fear of public spaces. These factors were significantly associated with nail-biting behaviour (p < 0.01 for all). No significant difference in Perceived Stress Scale scores was observed between students with and without onychophagia, and stress severity was not associated with the frequency or duration of nail-biting episodes.
Conclusion: Onychophagia was common among medical students and was significantly associated with smoking, positive family history, and fear of public spaces. Behavioural interventions are recommended among university students.
{"title":"Prevalence and correlates of onychophagia among Egyptian medical students: a cross-sectional study.","authors":"Asmaa Mohammad Ahmad Mohammad, Rabab Ahmed Abd El-Hai Hammad, Noha M Elghazally","doi":"10.1007/s44192-025-00327-x","DOIUrl":"10.1007/s44192-025-00327-x","url":null,"abstract":"<p><strong>Background: </strong>Onychophagia, or chronic nail biting, is a common body-focused repetitive behaviour often associated with psychological stress, anxiety, and perfectionism. Medical students may be at increased risk due to sustained mental and emotional pressures.</p><p><strong>Objectives: </strong>To assess the prevalence of onychophagia, identify associated risk factors, and examine the relationship between perceived stress levels and the frequency or severity of nail biting among medical students at Tanta University in Egypt.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 330 undergraduate students using a structured self-administered questionnaire comprising sociodemographic data, onychophagia-related items, and the Perceived Stress Scale (PSS).</p><p><strong>Results: </strong>57.3% of the students were actively practicing onychophagia, and it was reported more often among males (63.5%) than females (36.5%), but the difference was not statistically significant (p = 0.134). Among participants with onychophagia (n = 189), 18 (9.5%) were smokers, 63 (33.3%) reported a positive family history, and 30 (15.9%) reported fear of public spaces. These factors were significantly associated with nail-biting behaviour (p < 0.01 for all). No significant difference in Perceived Stress Scale scores was observed between students with and without onychophagia, and stress severity was not associated with the frequency or duration of nail-biting episodes.</p><p><strong>Conclusion: </strong>Onychophagia was common among medical students and was significantly associated with smoking, positive family history, and fear of public spaces. Behavioural interventions are recommended among university students.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":" ","pages":"195"},"PeriodicalIF":2.7,"publicationDate":"2025-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-20DOI: 10.1007/s44192-025-00343-x
Mohammad Abdullah Hameed, Taneer Abbas, Muhammad Muneeb Warriach, Natasha Nadeem, Ambreen Tauseef, Mohsin Ali Syed
{"title":"Prevalence of body dysmorphic disorder, gender differences and association with body mass index among medical students in Pakistan.","authors":"Mohammad Abdullah Hameed, Taneer Abbas, Muhammad Muneeb Warriach, Natasha Nadeem, Ambreen Tauseef, Mohsin Ali Syed","doi":"10.1007/s44192-025-00343-x","DOIUrl":"10.1007/s44192-025-00343-x","url":null,"abstract":"","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":" ","pages":"13"},"PeriodicalIF":2.7,"publicationDate":"2025-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12827839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Phthalates, ubiquitous environmental contaminants, are widely used in daily life. Although their adverse health effects across developmental stages have been well-documented, their impact on elderly populations remains unexplored. This study investigated the association between phthalate exposure and mental health issues (depression, anxiety, and stress). A community-based cross-sectional study was conducted among 688 individuals aged ≥ 60 years in Thailand. Phthalate exposure was assessed using five urinary phthalate metabolites: mono(2-ethylhexyl) phthalate (MEHP), monoisobutyl phthalate, mono-n-butyl phthalate (MnBP), monoethyl phthalate, and monomethyl phthalate. Mental health status was evaluated using the Depression Anxiety Stress Scales (DASS-21), a self-administered questionnaire that assesses depression, anxiety, and stress, along with demographic data. Binary logistic regression adjusted for potential confounders was used to analyze associations with mental health risks. The detection rates for the phthalate metabolites ranged between 31.83 and 96.08%, with MEHP being most frequently detected. Depression emerged as the most prevalent mental health condition. Among healthy participants, those in the highest tertile of urinary MEHP and MnBP levels exhibited significantly increased odds of anxiety, with adjusted odds ratios 3.13 (95% CI 1.37-7.12) and 2.28 (95% CI 1.03-5.06), respectively. Both metabolites exhibited a dose-response relationship (p-for-trend = 0.002 and 0.034, respectively). The number needed to harm was 5.66 for MEHP and 8.09 for MnBP. Associations were not observed in individuals with underlying chronic diseases. Furthermore, no association with depression or stress was observed. In conclusion, exposure to both high- and low-molecular-weight phthalates was associated with an increased risk of anxiety among healthy older adults. However, causal inferences were not confirmed owing to the study design. Longitudinal research is warranted to clarify the underlying mechanisms and inform mental health surveillance for older individuals.
邻苯二甲酸盐是一种普遍存在的环境污染物,在日常生活中被广泛使用。尽管它们在整个发育阶段对健康的不利影响已得到充分记录,但它们对老年人的影响仍未得到探索。本研究调查了邻苯二甲酸酯暴露与心理健康问题(抑郁、焦虑和压力)之间的关系。一项以社区为基础的横断面研究对泰国688名年龄≥60岁的个体进行了研究。使用五种尿邻苯二甲酸酯代谢物:邻苯二甲酸单(2-乙基己基)酯(MEHP)、邻苯二甲酸单异丁酯、邻苯二甲酸单正丁酯(MnBP)、邻苯二甲酸单乙酯和邻苯二甲酸单甲基酯来评估邻苯二甲酸暴露。使用抑郁焦虑压力量表(DASS-21)评估心理健康状况,这是一份自我管理的问卷,评估抑郁、焦虑和压力,以及人口统计数据。采用校正潜在混杂因素的二元逻辑回归分析与心理健康风险的关联。邻苯二甲酸酯代谢物检出率为31.83 ~ 96.08%,以MEHP检出率最高。抑郁症成为最普遍的心理健康状况。在健康参与者中,尿MEHP和MnBP水平最高的参与者表现出显著增加的焦虑几率,调整后的优势比分别为3.13 (95% CI 1.37-7.12)和2.28 (95% CI 1.03-5.06)。两种代谢物均表现出剂量-反应关系(p-for-trend分别= 0.002和0.034)。MEHP和MnBP需要伤害的数量分别为5.66和8.09。在有潜在慢性疾病的个体中未观察到相关。此外,没有观察到与抑郁或压力有关。总之,暴露于高分子量和低分子量邻苯二甲酸盐与健康老年人焦虑风险增加有关。然而,由于研究设计的原因,因果关系尚未得到证实。有必要进行纵向研究,以阐明潜在的机制,并为老年人的心理健康监测提供信息。
{"title":"Phthalate exposure and its impact on mental health risk in the elderly Thai population.","authors":"Orawan Kaewboonchoo, Maruth Bhrasartsuwan, Kraichat Tantrakarnapa, Chatchai Ekpanyaskul","doi":"10.1007/s44192-025-00314-2","DOIUrl":"10.1007/s44192-025-00314-2","url":null,"abstract":"<p><p>Phthalates, ubiquitous environmental contaminants, are widely used in daily life. Although their adverse health effects across developmental stages have been well-documented, their impact on elderly populations remains unexplored. This study investigated the association between phthalate exposure and mental health issues (depression, anxiety, and stress). A community-based cross-sectional study was conducted among 688 individuals aged ≥ 60 years in Thailand. Phthalate exposure was assessed using five urinary phthalate metabolites: mono(2-ethylhexyl) phthalate (MEHP), monoisobutyl phthalate, mono-n-butyl phthalate (MnBP), monoethyl phthalate, and monomethyl phthalate. Mental health status was evaluated using the Depression Anxiety Stress Scales (DASS-21), a self-administered questionnaire that assesses depression, anxiety, and stress, along with demographic data. Binary logistic regression adjusted for potential confounders was used to analyze associations with mental health risks. The detection rates for the phthalate metabolites ranged between 31.83 and 96.08%, with MEHP being most frequently detected. Depression emerged as the most prevalent mental health condition. Among healthy participants, those in the highest tertile of urinary MEHP and MnBP levels exhibited significantly increased odds of anxiety, with adjusted odds ratios 3.13 (95% CI 1.37-7.12) and 2.28 (95% CI 1.03-5.06), respectively. Both metabolites exhibited a dose-response relationship (p-for-trend = 0.002 and 0.034, respectively). The number needed to harm was 5.66 for MEHP and 8.09 for MnBP. Associations were not observed in individuals with underlying chronic diseases. Furthermore, no association with depression or stress was observed. In conclusion, exposure to both high- and low-molecular-weight phthalates was associated with an increased risk of anxiety among healthy older adults. However, causal inferences were not confirmed owing to the study design. Longitudinal research is warranted to clarify the underlying mechanisms and inform mental health surveillance for older individuals.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"194"},"PeriodicalIF":2.7,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12717321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}